As a leading 1-[4-(4-Butylcyclohexyl)Cyclohexyl]-4-Ethoxy-2,3-Difluoro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main application fields of 1- [4- (4-butylcyclohexyl) cyclohexyl] -4-ethoxy-2,3-difluorobenzene
1-% [4- (4-methylcyclohexyl) cyclohexyl] -4-ethoxy-2,3-difluorobenzene, which has important applications in medicine, materials science and other fields.
In the field of medicine, due to its unique chemical structure, it can be used as a key intermediate for the synthesis of specific targeted drugs. For example, in the development of some new anti-cancer drugs targeting specific cell receptors, the compound can construct a core structure of drug activity through a series of reactions, which can precisely act on cancer cell targets, improve drug efficacy and reduce damage to normal cells.
In materials science, it can be used to prepare high-performance liquid crystal materials. With its molecular shape and arrangement characteristics, it can regulate the liquid crystal phase transition temperature and optical properties. In new display technologies such as OLED (Organic Light Emitting Diode) and TFT-LCD (Thin Film Transistor Liquid Crystal Display), these materials are used to optimize the arrangement of the liquid crystal layer, improve the display resolution, contrast and response speed, and make the screen image clearer, more vivid colors and faster response.
At the level of scientific research and exploration, as an important substrate in organic synthetic chemistry, chemists have developed novel synthesis paths and methods by modifying and derivatization of functional groups, expanding the boundaries of organic chemistry knowledge, and providing ideas and foundations for the creation of more complex functional molecules.
What are the physical properties of 1- [4- (4-butylcyclohexyl) cyclohexyl] -4-ethoxy-2,3-difluorobenzene
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1 - [4 - (4 - cyclopropyl cyclopropane) cyclopropane] - 4 - ethoxy - 2,3 - difluorobenzene, its physical properties are quite unique.
In appearance, at room temperature, it is mostly colorless to slightly yellow transparent liquid, like a quiet water, clear and fluid, no impurities visible to the naked eye, the surface luster is delicate, and it can be seen as if it can reflect the world.
Its density is slightly larger than that of water, about [X] g/cm ³, in the container, it is calm and quiet, as if it contains endless mysteries. Just like the submerged jade contained in ancient books, although it is silent and silent, it has its own sense of heaviness.
In terms of boiling point, it is about [X] ° C. Under a specific temperature, this object will change from liquid to gaseous state, just like the change of exuberance and ascension, jumping from the liquid state to the gaseous state. When the temperature gradually rises, the thermal movement of molecules becomes more and more intense, breaking free from the shackles of the liquid phase and skyrocketing.
The melting point is about [X] ° C. When the temperature drops to this point, the molecular movement gradually slows down and gets closer to each other. It is like everything is dormant in the cold winter, arranged in an orderly manner, solidified and formed, and liquefied from agility to stability.
In terms of solubility, in common organic solvents such as ethanol and ether, the solubility is quite good, and it can be blended with them like water and water, and they are insoluble. Just like what the ancients said, "Birds of a feather flock together", in similar solvents, it shows good affinity, but in water, the solubility is very small, and the two seem to be distinct and difficult to blend.
The refractive index also has a specific value, which is about [X]. When light passes through this object, the light path will be deflected at a specific angle, just like light encounters strange forces in a mysterious environment, changing its original behavior and showing its unique optical properties, covering it with a layer of mystery, just like the strange changes of light in the illusion contained in ancient books.
What is the chemical stability of 1- [4- (4-butylcyclohexyl) cyclohexyl] -4-ethoxy-2,3-difluorobenzene?
The chemical stability of Fu 1 - [4 - (4 - methylcyclohexyl) cyclohexyl] - 4 - ethoxy - 2,3 - difluorobenzene is quite important.
The stability of this compound is related to many aspects. In terms of structure, the cyclic structure it contains imparts certain stability. The combination of methylcyclohexyl and cyclohexyl makes the molecular framework relatively stable. The carbon-carbon bond is difficult to break under normal conditions and can resist the attack of general chemical reagents.
Furthermore, the presence of ethoxy group, although the oxygen atom has a certain electronegativity, it is connected to the benzene ring and stabilizes the molecular system to a certain extent through the conjugation effect. The power supply of ethoxy group can disperse the electron cloud on the benzene ring, reducing the chance of attack by electrophilic reagents.
As for the 2,3-difluorobenzene part, the fluorine atom has strong electronegativity. Although its electron-absorbing induction effect is significant, it will reduce the electron cloud density of the benzene ring, which seems to weaken the stability of the benzene ring; however, the lone pair of electrons of the fluorine atom can be conjugated with the benzene ring, which will enhance the stability of the system to a certain extent. And after the fluorine atom is replaced, the
In common chemical environments, if there are no extreme conditions such as strong oxidizing agents, strong acids and bases, this compound should be quite stable. However, when exposed to high temperatures, strong oxidizing atmospheres or specific nucleophiles, or due to some active checking points in the structure, the stability is impaired.
In summary, 1 - [4 - (4-methylcyclohexyl) cyclohexyl] - 4 - ethoxy - 2,3 - difluorobenzene is stable under conventional conditions, but the change of its chemical stability in certain harsh environments needs to be carefully considered.
What are the preparation methods of 1- [4- (4-butylcyclohexyl) cyclohexyl] -4-ethoxy-2,3-difluorobenzene
To obtain 1 - [4- (4-methylcyclohexyl) cyclohexyl] - 4-ethoxy-2,3-difluorobenzene, the preparation method is as follows:
First, the target molecular structure can be constructed by selecting suitable starting materials through a step-by-step reaction. The benzene ring derivative containing the corresponding substituent is used as the starting material, such as the benzene compound with the appropriate halogen substitution, and the reagent containing the specific alkyl structure is reacted with the reagent.
First, the cyclohexyl-containing structure fragment is introduced by reacting the halogenated aromatic hydrocarbon with an organometallic reagent, such as Grignard reagent or lithium reagent. This step needs to be carried out under the condition of anhydrous and inert gas protection to ensure the smooth reaction. The reaction solvent is often anhydrous ether or tetrahydrofuran, and the reaction temperature is regulated according to the specific reagent and reaction activity.
Next, the intermediate that has been introduced into the structure is ethoxylated. This can be achieved by reacting sodium alcohol or sodium phenol with ethane halide under suitable alkaline conditions. The alkaline environment can promote the occurrence of nucleophilic substitution reactions to generate ethoxy groups in the target structure.
Subsequently, fluorine atoms are introduced at appropriate positions. This may require specific fluorination reagents, such as Selectfluor, etc. The fluorination reaction conditions are relatively harsh, and the reaction temperature, reagent dosage and reaction time need to be strictly controlled to ensure the accurate introduction of fluorine atoms to the 2,3-position and avoid side reactions such as excessive fluorination.
The whole synthesis process needs to be closely monitored, and the purity and structural correctness of the reaction products in each step can be confirmed by means of thin layer chromatography (TLC), nuclear magnetic resonance (NMR) and other analytical methods. At the same time, pay attention to the separation and purification operations in each step of the reaction, such as column chromatography, recrystallization method, etc., to obtain high-purity 1 - [4 - (4 - methylcyclohexyl) cyclohexyl] - 4 - ethoxy - 2,3 - difluorobenzene products.
How competitive is 1- [4- (4-butylcyclohexyl) cyclohexyl] -4-ethoxy-2,3-difluorobenzene in the market?
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1 - methyl - 4 - [4 - (4 - methylcyclohexyl) cyclohexyl] - 4 - ethoxy - 2,3 - difluorobenzene, its competitiveness in the market is also. This compound has a unique structure and contains groups such as methyl, ethoxy and fluorine atoms. The structure of methyl and cyclohexyl gives it specific spatial resistance and hydrophobicity, which can affect the interaction between molecules. The ethoxy group may change its solubility and electron cloud distribution, which has an important impact on its physical and chemical properties. The introduction of fluorine atoms significantly enhances the stability of the molecule and regulates its lipophilicity.
At the application level, due to its structure and properties, it may demonstrate advantages in the field of materials science. For example, in high-performance polymer additives, its unique molecular structure can optimize the thermal stability and mechanical properties of polymers. In electronic materials, its special electronic properties may help to improve the conductivity or dielectric properties of materials. In the field of medicine, its unique structure and properties may endow it with certain biological activities, such as as potential drug lead compounds, which can interact with specific biological targets to demonstrate the potential of treating diseases.
Looking at the market, with the development of science and technology, the demand for compounds with special properties is increasing. This 1-methyl-4- [4- (4-methylcyclohexyl) cyclohexyl] -4-ethoxy-2,3-difluorobenzene, with its unique structure-derived properties, has application prospects in materials, electronics, medicine and other fields. Therefore, it may be able to gain a place in the market competition by virtue of its characteristics and demonstrate good competitiveness in specific application scenarios.