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1,3-Dinitro-4-Fluorobenzene

1,3-Dinitro-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

925278

Chemical Formula C6H3F(NO2)2
Molar Mass 186.094 g/mol
Appearance Yellow - solid
Melting Point 55 - 57 °C
Boiling Point 254 - 256 °C
Density 1.624 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Flash Point 127.9 °C
Vapor Pressure Low vapor pressure at room temperature
Hazard Class Toxic, irritant

As an accredited 1,3-Dinitro-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - dinitro - 4 - fluorobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1,3 - dinitro - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. It must be kept in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to prevent chemical reactions.
Shipping 1,3 - dinitro - 4 - fluorobenzene is a hazardous chemical. It must be shipped in accordance with strict regulations. Use specialized containers, ensure proper labeling, and choose carriers experienced in handling such chemicals to guarantee safe transportation.
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1,3-Dinitro-4-Fluorobenzene 1,3-Dinitro-4-Fluorobenzene
General Information
Historical Development
1,3-Dinitro-4-fluorobenzene is also an organic compound. At the beginning of its development, chemists studied the physical properties of this substance and initially realized that the structure of this substance is specific and the reaction is unique. At that time, in the field of organic synthesis, people did not explore fluorinated nitrobenzene in depth.
After that, science and technology have gradually advanced, and instruments have been refined. Researchers have investigated its reaction mechanism in detail. After many attempts, it has been known that under specific conditions, it can be subtly changed with various reagents to form different products. This compound has made a name for itself on the road of pharmaceutical synthesis, providing a key intermediate for the creation of new drugs and helping to develop novel therapies.
Up to now, its preparation process has been continuously improved, its efficiency has increased, and its purity has also been excellent. In the field of materials science, it has also been involved in the research and development of new functional materials. Looking at its historical evolution, it has been unfamiliar since the beginning, and is now widely used in many fields. It can be said that remarkable achievements have been made, and the future development is expected to be even more brilliant.
Product Overview
1,3-Dinitro-4-fluorobenzene is an important raw material for organic synthesis. Its color is light yellow, crystalline, and has a special odor.
In this compound, the structure of nitro and fluorine atoms gives it unique chemical properties. Nitro activity is quite high, often used as a key check point in many chemical reactions, participating in nucleophilic substitution and other reactions. Fluorine atoms also make unique contributions, because of their strong electronegativity, they can affect the electron cloud distribution of molecules, which in turn affects the reaction activity and selectivity.
In the industrial field, 1,3-dinitro-4-fluorobenzene is often used in the preparation of fine chemicals, laying the foundation for the synthesis of medicines, pesticides and other products. However, it is toxic and dangerous, and it is necessary to operate with caution and follow strict safety procedures to prevent harm to people and the environment.
Physical & Chemical Properties
1,3-Dinitro-4-fluorobenzene, also an organic compound. Its color or light yellow, the shape is crystalline, and it has a pungent odor. Melts in organic solvents, but slightly soluble in water.
Due to its chemical properties, it contains nitro and fluorine atoms, which are abnormally active. Nitro has strong electron absorption, causing the electron cloud density of the benzene ring to drop, making nucleophilic substitution easy. Although fluorine atoms are small, they have strong electronegativity, which increases the reactivity.
In terms of their physical rationality, the melting point is about 27-28 ° C, and the boiling point is quite high. Because of its structure and group characteristics, it has such physical and chemical characteristics, and is widely used in organic synthesis and other fields.
Technical Specifications & Labeling
1,3-Dinitro-4-fluorobenzene is also an important substance for chemical research. Its process specifications and identification (product parameters) are very important. The preparation of this substance requires precise methods, the raw materials must be pure, and the operation should be careful. The reaction conditions should be controlled at a specific temperature and pressure. If the temperature is in a certain range, the pressure can be adjusted to prevent accidents and ensure the quality of the product.
In terms of identification, its name should be displayed on the packaging, accompanied by chemical formula and description of properties, such as color, taste and state. The hazard level should be clearly marked, and a warning icon should be displayed to show that it is toxic, explosive and other risks. In addition, it is necessary to specify the product parameters, such as purity and impurity limits, so that the user can clarify its characteristics for scientific research and production purposes. Only by following this specification and marking can it be used safely and effectively.
Preparation Method
The method of making 1,3-dinitro-4-fluorobenzene is related to raw materials and production process, reaction steps and catalytic mechanism. First take fluorobenzene as raw material, supplemented with concentrated nitric acid and concentrated sulfuric acid. In a suitable device, control the temperature moderately, slowly inject acid into fluorobenzene, stir well. This step needs to be cautious, because the reaction is strong, and it is easy to risk if the temperature is too high.
After nitrification, nitro groups are added to the para-position and ortho-position of fluorobenzene to generate 1,3-dinitro-4-fluorobenzene and a small amount of by-products. After the reaction is completed, neutralize with alkali solution, take the organic phase in a separate solution, and then purify the product by distillation and recrystallization. The sulfuric acid and nitric acid used in
are both nitrifiers and catalysts in the reaction to promote the rapid progress of the reaction. And precise temperature control and uniform stirring speed have a great impact on the purity and yield of the product. In this way, relatively pure 1,3-dinitro-4-fluorobenzene can be obtained for various chemical applications.
Chemical Reactions & Modifications
Nowadays, there are 1,3-dinitro-4-fluorobenzene, which can be studied in the reaction and modification of chemical. In the chemical reaction, the activity of fluorine atoms is very different, and its molecular structure can be changed due to various reactions of nucleophilic substitution.
Looking at past experiments, nucleophilic reagents were often used to attack fluorine, and fluorine was easily replaced by other groups. This is the main characteristic of its reaction. However, the control of the reaction conditions is related to the purity and rate of the product.
If you want to modify it, you can use different nucleophilic reagents to adjust its substituents to change its physical and chemical properties. Or you can start at its nitro group and perform reactions such as reduction, and you can also get products with different properties.
In summary, 1,3-dinitro-4-fluorobenzene has great potential for chemical reaction and modification, and good research will surely lead to new gains in chemical and material fields.
Synonyms & Product Names
1,3-Dinitro-4-fluorobenzene is also a chemical substance. Although its name is the same in the industry, it is also known as other people. Looking at the ancient books, or "4-fluoro-1,3-dinitrobenzene", this is based on the name of its atomic ordering, which means the same as the original name, but the expression is slightly different.
It is also known for its characteristics and uses. In the field of chemical synthesis, because of its active nature, it is often a key agent in the reaction, so it is also called "active nitrofluorobenzene". Although the names are different, they all refer to this substance. Its various aliases are for the convenience of communication in the industry, and also help to clarify the characteristics and applications of this product in different situations. However, fundamentally, they are all synonymous terms of 1,3-dinitro-4-fluorobenzene, which refer to one thing.
Safety & Operational Standards
In the case of 1,3-dinitro-4-fluorobenzene, it is also a chemical substance. It is safe and dangerous to the operation.
Where this substance is exposed, its properties must be checked first. 1,3-dinitro-4-fluorobenzene has a strong reaction activity, and its toxicity cannot be ignored. When operating, it is necessary to pass through a good place to prevent harmful evaporation and accumulation.
If you want to take it, use suitable utensils, and make it suitable, do not let it fall. If it is accidentally released, it is cleaned according to a specific method. If this object encounters fire or high temperature, there is a risk of explosion, so there must be no open flame and high temperature source around.
If it is not stored, it should be placed in the air, dry and clear, oxidized, raw materials, etc., to prevent biochemical reactions.

For those who are involved in the operation, they must be subject to the problem of hard work and are familiar with the way of emergency treatment. If the skin is accidentally connected, wash it with a large amount of water at high speed, and seek medical treatment. If inhaled, it will be moved to the air to freshen it, and artificial respiration must be performed.
For the operation of 1,3-dinitro-4-fluorobenzene, it is necessary to keep the operation safe and not slack a little, so as to ensure the safety of people and make it profitable.
Application Area
1,3-Dinitro-4-fluorobenzene is also one of the chemical products. Its application field is quite wide. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs to cure various diseases. In the field of materials science, it also has unique uses, or can improve the properties of materials to make them more suitable for specific needs.
In the past, the exploration and application of various chemical products relied on the diligent research of scholars. 1,3-dinitro-4-fluorobenzene is the same. After many experiments and analysis, its characteristics and applications are clarified. In the reaction, it often exhibits active properties and can combine with other substances to derive various products.
Today, science and technology are improving, and the application research of 1,3-dinitro-4-fluorobenzene has not stopped. Scientists hope to expand its application field and explore more potential value to benefit the world, so that this chemical product can bloom more brilliantly in various fields.
Research & Development
Wutao is dedicated to the research of 1,3-dinitro-4-fluorobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
Initially, its structure and reaction characteristics were investigated, and many experiments were conducted to clarify its chemical activity laws. During this period, the reaction phenomena under different conditions were carefully observed, the data were recorded in detail, and the reaction mechanism was analyzed.
Then, the synthesis path was tried to be optimized. After repeatedly adjusting the ratio of raw materials, the reaction temperature and time, a more efficient method was finally obtained to improve the purity and yield of the product.
And considering its application and expansion, this compound may be used to prepare new materials or emerge in the field of drug research and development. I will make unremitting efforts to promote its development and contribute to the field of chemistry, so as to promote the advancement of science and technology and benefit the world.
Toxicity Research
Since modern times, chemical refinement, and various compounds have emerged. Today, there is 1,3-dinitro-4-fluorobenzene, which has attracted much attention in our toxicological research.
1,3-dinitro-4-fluorobenzene, its strong nature and strong toxicity. After many investigations, its toxicology is complex. After entering the body, it can disturb the normal metabolism of cells. According to various experiments, cells are invaded by it, and their vitality is gradually lost, their metabolism is disordered, and their function is weakened.
And this substance is also difficult to degrade in the environment. If it persists for a long time, it may be a disaster to the ecology. Surrounding organisms are harmed by it, or their growth is blocked, or their reproduction is difficult.
We should study its toxicity in depth with caution. Strive to clarify the mechanism, find a feasible way for protection and detoxification, and protect the well-being of the people and the well-being of the ecology.
Future Prospects
There is a thing today, named 1,3-dinitro-4-fluorobenzene, which has extraordinary potential for our chemical researchers. It may emerge in various fields of chemical industry.
Looking at its characteristics, the reactivity is different, and many new paths can be opened up. In the future, it is expected to pave a way for the creation of materials. The new materials may have excellent performance, suitable for cutting-edge fields such as electronics and aerospace, and improve the performance of equipment. It is durable, lightweight and portable.
Furthermore, the way of medical research and development also has broad prospects. With its unique structure, it may be able to generate new agents, overcome difficult diseases, and seek well-being for all living beings. Although there may be thorns in the road ahead, our researchers maintain a resolute heart, explore the hidden, and hope to do their best in the unfinished time, use it for the world, and achieve unparalleled achievements, in recognition of the power of science, benefiting all people, and looking forward to the future.
Where to Buy 1,3-Dinitro-4-Fluorobenzene in China?
As a trusted 1,3-Dinitro-4-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dinitro-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-dinitro-4-fluorobenzene?
1,3-diamino-4-hydroxyquinoline is an important organic compound. It has a wide range of main uses and can be used as a key drug intermediate in the field of medicine. The synthesis of many antibacterial and anticancer drugs often relies on it as the starting material. Through a series of chemical reactions, delicate molecules are constructed to prepare drugs with specific pharmacological activities and achieve the purpose of treating diseases.
In the dye industry, 1,3-diamino-4-hydroxyquinoline also plays an important role. Due to its unique chemical structure, it can endow dyes with excellent dyeing properties. The dyes made on this basis have good affinity for a variety of fibrous materials, high dyeing fastness, and can dye colorful and long-lasting fabrics, meeting the needs of the textile industry for high-quality dyes.
Furthermore, in the field of materials science, it can be used to prepare functional materials. Because it contains specific functional groups, it can be chemically modified or polymerized to be introduced into the material matrix, imparting special properties such as fluorescence and adsorption to the material, and has potential applications in optical materials, adsorption and separation materials.
Although "Tiangong Kaiwu" does not directly record 1,3-diamino-4-hydroxyquinoline, it shows the ancient understanding and utilization wisdom of various substances, which is consistent with the current application concept of this compound in many fields. All are for the purpose of human beings to improve life and promote scientific and technological progress through the mastery of material properties.
What are the physical properties of 1,3-dinitro-4-fluorobenzene?
1% 2C3-diamino-4-hydroxyanthraquinone is an organic compound. Its physical properties are particularly important and it is widely used in the chemical and material fields. The following are detailed:
1. ** Appearance **: Usually a purple-red crystalline solid with bright color. This appearance feature is easy to identify in many substances. When applied in the dye industry, it can provide a unique color basis.
2. ** Melting point **: High melting point, about 243-245 ° C. This characteristic makes it stable in high temperature environments. During specific processing, it can maintain its own structure and properties, and it is not easily melted and deformed due to temperature rise, ensuring product quality and performance.
3. ** Solubility **: Slightly soluble in water, but soluble in some organic solvents, such as pyridine, nitrobenzene, etc. This solubility enables it to disperse and react in different solvent systems. During the preparation of dyes, it can be dissolved with the help of suitable organic solvents and uniformly dispersed in fabrics and other substrates to achieve the purpose of dyeing.
4. ** Density **: The density is relatively large, and the specific value will vary depending on the crystal form and purity. Greater density affects its sedimentation and dispersion behavior in the medium. In suspensions or emulsion systems, density factors need to be considered to ensure uniform dispersion.
5. ** Sublimation **: Under certain conditions, it has sublimation, that is, the solid state is directly converted into a gaseous state. This property can be used in some separation and purification processes. By controlling temperature and pressure, 1% 2C3-diamino-4-hydroxyanthraquinone is sublimated and separated from impurities to improve purity.
6. ** Hygroscopicity **: It has certain hygroscopicity and can absorb moisture in the air. When storing and using, pay attention to the ambient humidity to avoid mass changes and agglomeration caused by moisture absorption, which will affect the performance of use.
What are the chemical properties of 1,3-dinitro-4-fluorobenzene?
1,3-Diamino-4-hydroxyquinoline is an organic compound. Its chemical properties are quite unique, let me tell you in detail.
This compound is basic because it contains amino groups. The nitrogen atom in the amino group has lone pairs of electrons, which can accept protons. In acidic solutions, it is easy to combine with protons to form a genus of ammonium salts. In case of hydrochloric acid, it can form the corresponding ammonium salt, which is one of its important acid-base properties.
Furthermore, the presence of hydroxyl groups also gives it different properties. Hydroxyl groups can participate in many chemical reactions, such as esterification reactions. In the case of carboxylic acids or their derivatives, under suitable conditions, hydrogen atoms in the hydroxyl group can be replaced by acyl groups to form ester compounds. And the hydroxyl group can form hydrogen bonds, which has a deep impact on its physical properties, such as the increase of the melting boiling point and the change of solubility. In water, its solubility may be improved due to the action of hydrogen bonds.
The conjugated system of 1,3-diamino-4-hydroxyquinoline cannot be ignored. The conjugated structure of the quinoline ring makes it stable to a certain extent. At the same time, the conjugated system has a significant impact on its optical properties, or can cause it to absorb or emit at specific wavelengths, which may have potential uses in spectral analysis and other fields.
In addition, the amino and hydroxyl groups of the compound can be used as active check points to participate in nucleophilic substitution reactions. The nitrogen atom of the amino group and the oxygen atom of the hydroxyl group have good nucleophilicity due to their lone pair electrons, which can attack suitable electrophilic reagents and generate new compounds, which have broad application prospects in the field of organic synthesis.
What is the production method of 1,3-dinitro-4-fluorobenzene?
The preparation method of 1% 2C3-dihydroxy-4-methoxybenzene is related to the technology of chemical synthesis. In the context of "Tiangong Kaiwu", although the chemical synthesis technology at that time was very different from today, there is still a lot of wisdom to learn from.
If you want to make this thing, you can first take suitable natural raw materials. Ancient craftsmen often look for opportunities for chemical changes in natural things. Or select plant rhizomes, fruits, etc. containing benzene structures, and carefully screen them to find the available ones.
The first step is to purify the selected raw materials and remove their impurities. If you need to break and grind them, you should also be careful to make the particle size of the raw materials suitable to facilitate subsequent reactions. This is like the ancient drug processing, fine operation, in order to preserve its properties.
The second rule, you can borrow the power of water and fire. In a special kettle, add an appropriate amount of water or other suitable solvents to slow down the frying. The size of the fire and the frying time need to be precisely controlled. Like the ancient alchemy, the temperature is the key to success or failure. In this process, the composition of the raw material or due to the action of solvents and heat, gradually changes, resulting in the initial product containing the target structure.
Furthermore, or the method of fractionation and extraction. Although there is no precision instrument in ancient times, there are simple means. For example, with different boiling points, the method of distillation is used to separate the product from the impurities. Extraction may use natural oils and other substances to enrich the target product by taking advantage of the difference in solubility.
In addition, or through multi-step reactions, the structure is gradually modified. Such as the introduction of hydroxyl groups, methoxy groups and other groups, or the use of acid-base agents, or the use of natural enzymes (although the name of enzymes was unknown at that time, or enzymes containing enzymes were used) to promote the reaction. Each step requires detailed observation of the reaction phenomenon, and according to its changes, the operation is adjusted to achieve the purpose of preparing 1% 2C3-dihydroxy-4-methoxylbenzene. This preparation process is actually a combination of ancient people's insights into the physical properties and changing laws of nature, and the experience and skills obtained through repeated attempts.
What are the precautions when using 1,3-dinitro-4-fluorobenzene?
When using 1% 2C3-diamino-4-hydroxybenzene, there are indeed many things to pay attention to.
First, it is related to safety protection. This substance is toxic and irritating. During operation, be sure to wear suitable protective equipment, such as gloves, goggles and gas masks. To prevent it from coming into direct contact with the skin and eyes, if inadvertently, rinse with plenty of water immediately, and seek medical attention in time depending on the situation. Inhalation of its dust or volatile gases may also endanger health, so the operation should be carried out in a well-ventilated place, or with the help of ventilation equipment, to reduce the concentration of harmful substances in the air.
Second, it involves storage points. Store it in a cool, dry and ventilated place, away from fires and heat sources. Due to its nature or instability, it may be dangerous to heat, open flames, etc. At the same time, it should be stored separately from oxidants, acids, etc., to avoid chemical reactions caused by mixed storage.
Third, about the specifications for use. When taking it, it should be strictly carried out in accordance with the specified dosage and operating procedures. Weighing should be accurate to avoid the risk of waste and excessive use. When used for specific reactions or product preparation, temperature, time and other parameters should be controlled according to the reaction conditions and requirements to ensure the smooth progress of the reaction and product quality. In addition, the waste generated during use should be properly handled in accordance with relevant environmental protection regulations and should not be discarded at will to avoid pollution to the environment.
In conclusion, the use of 1% 2C3-diamino-4-hydroxybenzene must be cautious and strictly follow all precautions to ensure personal safety, environmental safety and use effect.