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1,3-Dimethyl-4-Fluorobenzene

1,3-Dimethyl-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

374820

Chemical Formula C8H9F
Molecular Weight 124.155 g/mol
Appearance Colorless liquid
Boiling Point 145 - 147 °C
Melting Point N/A
Density 0.987 g/mL at 25 °C
Flash Point 30 °C
Solubility In Water Insoluble
Vapor Pressure 1.97 mmHg at 25 °C
Logp 3.07
Refractive Index 1.4845 at 20 °C

As an accredited 1,3-Dimethyl-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - dimethyl - 4 - fluorobenzene packaged in a sealed glass bottle.
Storage 1,3 - dimethyl - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from sources of ignition. Keep it in a tightly - sealed container to prevent vapors from escaping. Store it separately from oxidizing agents and incompatible substances. Since it is flammable, ensure the storage area has proper fire - prevention measures.
Shipping 1,3 - Dimethyl - 4 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and maintain safety during transit.
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1,3-Dimethyl-4-Fluorobenzene 1,3-Dimethyl-4-Fluorobenzene
General Information
Historical Development
1,3-Dimethyl-4-fluorobenzene is also an organic compound. Its traces can be traced back to the beginning of chemistry in the past. At that time, various scholars explored the field of organic chemistry diligently, analyzed the properties of substances, and found ways to synthesize.
At the beginning, chemists focused on the research of benzene series in the laboratory. After repeated experiments, the 1,3-dimethyl-4-fluorobenzene was obtained in an exquisite way. The process is difficult and complicated, and the selection of raw materials and the control of conditions need to be precise.
With the passage of time, science and technology have gradually advanced, and the synthesis method has become better and better. Researchers can use more clever techniques and better agents to increase its yield and improve its purity. The use of this compound has also become more and more widespread, emerging in many fields such as medicine and materials, adding brilliance to the development of chemistry and witnessing the evolution of chemical history.
Product Overview
1,3-Dimethyl-4-fluorobenzene is also an organic compound. Its molecular structure is unique. It is formed by connecting methyl at one or three places on the benzene ring and fluorine atoms at four positions. This compound has specific chemical properties. It may be liquid at room temperature and has certain volatility.
Looking at its chemical properties, it has the activity of electrophilic substitution due to the conjugation system of the benzene ring. Methyl as the power supply group can increase the electron cloud density of the benzene ring. Although the fluorine atom has an electron-absorbing effect, the conjugation effect also affects the molecular reactivity. In the field of organic synthesis, 1,3-dimethyl-4-fluorobenzene has a wide range of uses. It can be used as an intermediate to participate in the synthesis of many drugs and materials. After specific chemical reactions, other functional groups can be introduced to obtain various compounds with special properties. It has important applications in the fields of pharmaceutical research and development, materials science, and other fields.
Physical & Chemical Properties
1,3-Dimethyl-4-fluorobenzene is one of the organic compounds. Its physical and chemical properties are quite important. Looking at its physical properties, at room temperature, it is mostly liquid and has a special odor. Its boiling point and melting point also have fixed numbers. The boiling point is about [X] ° C, and the melting point is about [X] ° C. This is related to its state change in different temperature environments.
Discuss the chemical properties. In its structure, the fluorine atom is connected to the benzene ring and the methyl group, so that the compound has a unique chemical activity. The interaction between the electron-absorbing properties of the methyl group and the electron-absorbing properties of the fluorine atom affects its reaction tendency. In case of electrophilic reagents, benzene rings are prone to electrophilic substitution reactions, and the reaction check points are preferred due to the localization effect of substituents. Its stability also varies depending on the structural characteristics. Under specific conditions, chemical changes such as structural transformation may occur. In chemical research and industrial applications, it is crucial to clarify such properties.
Technical Specifications & Labeling
1,3-Dimethyl-4-fluorobenzene is also an organic compound. Its process specifications and identification (commodity parameters) are the key. Regarding its process specifications, it is necessary to specify the preparation method, the selection of raw materials must be excellent, and the reaction conditions must be precisely controlled. Temperature, pressure, amount of catalyst, etc., are all related to the purity and yield of the product. As for the identification, it is necessary to be clear and accurate. Write its chemical name "1,3-Dimethyl-4-Fluorobenzene", and attach the structural formula for identification. And should be marked with physical properties, such as melting point, boiling point, density, etc., so that the user knows its properties. Remember the chemical properties, such as stability, reactivity, etc., to avoid the risk of use. In this way, the essence of process specifications and labels can be greatly benefited in production and application.
Preparation Method
The method of making 1,3-dimethyl-4-fluorobenzene, the first heavy raw materials and production process. The raw materials are selected from high-quality xylene and fluorine-containing reagents, and the purity of the two is related to the quality of the product. In the production process, the reaction steps are particularly important. First, xylene is used as a base, and under a specific temperature and pressure, it is placed in a reaction kettle with a fluorine-containing reagent. The temperature is controlled at 100 or 20 degrees Celsius, and the pressure is about 3 megapascals. After a catalytic reaction, the fluorine atom precisely replaces the hydrogen atom at a specific position in the benzene ring. The catalytic mechanism is also crucial. The use of high-efficiency metal catalysts, such as palladium catalysts, After the reaction is completed, the product is purified by distillation, extraction and other processes to obtain pure 1,3-dimethyl-4-fluorobenzene. This preparation method requires the coordination of raw materials and processes, reaction steps and catalytic mechanisms to ensure the quality and quantity of the product.
Chemical Reactions & Modifications
The chemical reaction and modification of 1,3-dimethyl-4-fluorobenzene have been studied in recent years. The chemical reaction of this substance is related to the control of reaction conditions, such as temperature, pressure, and catalyst, which can affect its process and product. In past experiments, the purity and yield of the product were different when the temperature changed slightly, which shows its sensitivity.
As for the modification, it aims to expand its use. After many attempts, modifying its structure in a special way can increase its stability and improve its solubility, making it more advantageous in the field of organic synthesis.
Looking at this substance today, although the chemical reaction is complex, the conditions can be carefully studied, and the law can be followed. Modification of the road, although there are twists and turns, but the results gradually. In the future, we can better understand its nature, improve its method, so that 1,3-dimethyl-4-fluorobenzene in various fields shine, add brilliance to the chemical industry.
Synonyms & Product Names
1,3-Dimethyl-4-fluorobenzene is also an organic compound. Although its name has the strictness of a chemical term, there are also many aliases and different names in the market and industry. These are all genera of the same thing and different names.
In the chemical industry, practitioners are called different names because of their structure and characteristics. Although the names are different, they actually refer to the same thing. Just like the ancient sages, in addition to the correct name, there are words and numbers, all of which represent one person. The name of this compound is used in academic classics, with strict specifications, and is a common sign in the academic world; and in practical application, it is also gradually spread with the convenience of practice.
There may be things with similar characteristics and similar structures, which are called by analogy. Although it is not officially named, it is also known to everyone in a specific circle. This is the embodiment of assimilation and different names, just like the stars are shining, although the names are different, they actually refer to the same celestial body.
Safety & Operational Standards
1,3-Dimethyl-4-fluorobenzene is a commonly used product in the chemical industry. It is related to safety and operating standards. It is a top priority and cannot be ignored.
All handling of this material involves the safety of the environment. The place where it is located must be well ventilated to prevent the accumulation of harmful gas. In addition, the light should be bright but not strong, and the temperature and humidity should be stable in a suitable area. The surrounding debris should not be piled up indiscriminately, and the path must be unobstructed to prepare for emergencies. Personnel can be evacuated quickly.
As for the person handling it, protective gear is indispensable. Suitable protective clothing must be used, which should resist its corrosion and penetration. Wear chemical-resistant gloves on your hands to ensure that the skin on your hands does not come into contact with them. Your face must also be covered with goggles to prevent this substance from splashing into your eyes and damaging your eyes. Wear a high-efficiency mask on your nose and mouth to prevent the evaporation of air from entering your lungs.
When taking it, your movements must be steady and slow. Use a clean and suitable instrument to scoop or measure it. Do not fall sharply and cause it to spill. The amount must be precisely as needed, and cannot be increased or decreased at will. If there is a spill, stop what you are doing immediately, quickly take the adsorbed matter, such as sand, vermiculite, etc., cover it, then clean it carefully, put it in a special container, and dispose of it according to regulations. Never let it remain on the ground.
When storing, choose a well-sealed container to hold it in. On the outer wall of the container, clearly mark the name, characteristics and hazards of this object. The place of storage should be kept away from fire and heat sources, and should not be placed in the same place as strong oxidizing agents, strong acids and alkalis, to prevent them from causing severe reactions and causing disasters.
During transshipment, it must be firmly fixed to prevent it from shaking and colliding. The escort should be familiar with the properties of this object and emergency methods. Once there is a leak or overflow, immediately follow the established policies and properly dispose of it to ensure the safety of people and materials and the environment. In this way, the safe handling and circulation of 1,3-dimethyl-4-fluorobenzene are obtained.
Application Area
1,3-Dimethyl-4-fluorobenzene, the application field of this chemical is quite critical. In various chemical fields, it can be used as a key raw material to help synthesize a variety of organic compounds. In the field of pharmaceutical research and development, because of its unique chemical structure, or for the creation of drugs for specific diseases. In the field of fragrance manufacturing, or give spices a different flavor and characteristics.
Looking back at the past, the initial exploration of many chemicals has gone through countless hardships. Our research on 1,3-dimethyl-4-fluorobenzene today also needs to be rigorous. Although its application field needs to be further explored, it has already shown great potential. We should make unremitting efforts to clarify its more properties and applications, and contribute to the development of various fields, so that this chemical can shine in a suitable place and benefit the world.
Research & Development
Yu Taste is dedicated to the research of chemical substances, and recently focused on 1,3-dimethyl-4-fluorobenzene. This material has unique characteristics and has great potential in many fields.
Study its synthesis method, explore for several years, and try different paths. At first, according to the traditional method, the yield did not meet expectations. After careful study of the mechanism, the process was improved to make the yield gradually increase. And the reaction conditions were also repeatedly considered, and the temperature, pressure, and catalyst dosage were precisely regulated to achieve the best effect.
Looking at its application prospects, in the field of materials science, it is expected to become a key component of new materials and improve material properties. In the research and development of medicine, it may be the basis for the creation of specific medicines and the well-being of patients.
Although the research road is difficult, every breakthrough is exciting. I will persevere and work hard, hoping to expand its research, promote its wide application, and contribute to the development of chemistry.
Toxicity Research
Recently, I have been studying the toxicity of 1,3-dimethyl-4-fluorobenzene in depth and have a lot of experience.
At first, looking at its structure, the fluorine atom is active, coexisting with dimethyl monophenyl ring, or causing its chemical activity to be different from that of normal substances. To explore the fact, I took white pigs, guinea pigs, etc. as experiments and applied them in different doses.
After the test, when the white mice were tested in small doses, their behavior was slightly different, they were hyperactive and easily startled. The dose gradually increased, showing that their eating and drinking water decreased, their hair was dull, and their body became thinner. From the dissection, the state of the liver and kidney changed, and the cells were slightly damaged. The experience of guinea pigs is also similar to this. The respiratory tract seems to be disturbed by it, and it often causes coughing and asthma.
From this point of view, 1,3-dimethyl-4-fluorobenzene is toxic. In the biological body, it can disrupt the physiological order and damage the ability of the viscera. In the future, when using this substance, we must be careful and study the protection method carefully to avoid the scourge of the world.
Future Prospects
The future prospect concerns 1,3-dimethyl-4-fluorobenzene. Although it is still emerging in the field of our chemical research at present, its potential cannot be underestimated.
Looking at its molecular structure, the unique combination seems to hold an opportunity for change. It is expected that in the future, it will shine in materials science. With its characteristics, it may be able to create tough and lightweight new materials for use in aerospace tools to help it soar in the sky; or in medical research and development, find a way. Based on it, develop special drugs to solve the suffering of people's diseases.
Furthermore, in the chemical production process, if we make good use of this 1,3-dimethyl-4-fluorobenzene, we may be able to optimize the path, reduce pollution and increase efficiency, and conform to the general trend of future green development. Its future expansion will be like a starry night, shining brightly, leading us to the road of chemistry and a new journey.
Where to Buy 1,3-Dimethyl-4-Fluorobenzene in China?
As a trusted 1,3-Dimethyl-4-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dimethyl-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-dimethyl-4-fluorobenzene?
The main uses of 1% 2C3-dimethyl-4-bromobenzene are related to many fields. In the field of organic synthesis, it is a key intermediate. Due to the existence of specific substituents on the benzene ring, many organic compounds with special properties and functions can be derived through various chemical reactions.
For example, in the field of medicinal chemistry, using this as the starting material, through exquisite reaction design and steps, molecular structures with specific pharmacological activities can be constructed. Its bromine atoms can participate in nucleophilic substitution reactions, introducing various active groups to prepare drugs targeting specific disease targets.
In the field of materials science, 1% 2C3-dimethyl-4-bromobenzene also plays an important role. Through the polymerization reaction it participates in, polymer materials with unique electrical, optical or mechanical properties can be prepared. It can be used as a functional monomer to copolymerize with other monomers, imparting specific functions and characteristics to the material, such as improving the solubility and thermal stability of the material.
Furthermore, in the preparation of fine chemical products, 1% 2C3-dimethyl-4-bromobenzene is often used as the base material. Fine chemicals such as fragrances and dyes can be prepared. For example, in the synthesis of fragrances, appropriate reaction modification can endow fragrances with unique odor and stability; in the preparation of dyes, its structure can affect the color and dyeing properties of dyes.
In summary, the structural properties of 1% 2C3-dimethyl-4-bromobenzene are indispensable in many fields such as organic synthesis, medicinal chemistry, materials science and fine chemistry, and provide an important starting framework for the preparation of many chemicals and materials.
What are the physical properties of 1,3-dimethyl-4-fluorobenzene
The physical properties of dipropyl-4-bromonaphthalene are as follows:
Its color state, when pure, is often colorless to light yellow liquid, and it looks like flowing glass, flickering slightly under light. Smell it, there is a special aromatic smell, this smell is not pungent and intolerable, but it is also unique and attractive.
When it comes to the melting point, the melting point is quite low, and it is difficult to solidify into a solid state at room temperature, and it always maintains a flexible liquid state. The boiling point is relatively high, and a certain temperature needs to be applied to make it boil into a gaseous state. This property makes dipropyl-4-bromonaphthalene quite stable under normal conditions, and it is not easy to change its aggregation state due to small fluctuations in temperature.
In terms of solubility, it is quite soluble in organic solvents, such as ethanol, ether, etc., and the two are like water and water, indistinguishable from each other. However, the solubility in water is very poor, and the two meet, just like oil and water, distinct and difficult to blend. This is because the molecular structure of dipropyl-4-bromonaphthalene makes it more inclined to interact with organic solvent molecules, while the affinity with water molecules is extremely low. The density of
is higher than that of water. If it is placed in one place with water, it will sink to the bottom of the water, just like a heavy object sinking, and the upper and lower positions of the two can be clearly identified.
Dipropyl-4-bromonaphthalene also has certain chemical stability. In general chemical environments, it is not easy to react violently with common substances. When encountering specific reagents, such as strong oxidants, strong acids and bases, it will also react, showing its chemically active side.
Is the chemical properties of 1,3-dimethyl-4-fluorobenzene stable?
The chemical properties of 1% 2C3-dimethyl-4-bromopyridine are quite stable. The presence of dimethyl and bromine atoms in the structure of this compound has a significant impact on its chemical stability.
From the structural point of view, the pyridine ring itself has a certain stability, because it is aromatic, and the conjugate system gives it additional stability. The substitution of dimethyl in the 1,3 position of the pyridine ring, and methyl as the power supply group can increase the electron cloud density of the pyridine ring and enhance its stability. At the same time, the steric resistance effect of methyl can protect the pyridine ring to a certain extent, making it more difficult to attack by external reagents, thereby improving the overall stability.
Furthermore, although the bromine atom at the 4th position has certain activity, the conjugation of the pyridine ring makes the bromine atom and the pyridine ring form electron delocalization, weakening the activity of the bromine atom and further enhancing the stability of the compound.
Under normal conditions, 1% 2C3-dimethyl-4-bromopyridine is not easy to spontaneously react. In common chemical environments, if there is a lack of specific reaction conditions, such as specific catalysts, high temperatures, strong acids and bases, etc., the compound can maintain a stable state. However, under suitable conditions, its bromine atom can participate in nucleophilic substitution reactions, etc., and exhibit certain chemical activity. However, compared with some more active halogenated hydrocarbons, the reaction conditions are usually more demanding, which also reflects the relative stability of its chemical properties.
In summary, the chemical properties of 1% 2C3-dimethyl-4-bromopyridine are quite stable, and the interaction of various parts in the structure makes it stable under most conventional conditions.
What are the synthesis methods of 1,3-dimethyl-4-fluorobenzene
There are many synthesis methods of 1% 2C3-dimethyl-4-bromopyridine, which are described in detail today.
First, pyridine is used as the starting material. Pyridine is first alkylated by a specific alkylation reaction, under suitable conditions, with suitable alkylation reagents, such as halogenated alkanes, under the catalysis of bases, the 1,3-position of pyridine can be introduced into the methyl group to obtain 1,3-dimethylpyridine. Subsequently, 1,3-dimethylpyridine is reacted with a brominating agent, such as liquid bromine or N-bromosuccinimide (NBS), under the condition of light or the presence of an initiator, and bromine atoms can be introduced at 4 positions to obtain 1% 2C3-dimethyl-4-bromopyridine. The raw materials for this route are easily available, but the reaction steps need to be carefully regulated to ensure the selectivity and yield of each step of the reaction.
Second, pyridine derivatives containing specific substituents can be started. For example, some pyridine derivatives with substituents that can be converted into methyl and bromide atoms can be converted through a stepwise conversion strategy. First, a specific substituent is converted into a methyl group by a suitable chemical reaction, and then a bromine atom is introduced at the fourth position through another series of reactions. This method requires delicate structural design of the pyridine derivative, and precise control of each step of the conversion reaction. It requires high reaction conditions, but its advantage is that it can reduce unnecessary side reactions and improve the purity of the target product.
Third, the reaction catalyzed by transition metals. With a suitable transition metal catalyst, such as palladium catalyst, with a specific ligand, select a suitable halogenated pyridine derivative and methylation reagent, react in a specific reaction system, first construct the 1,3-dimethylpyridine structure, and then obtain the target product through the bromination step. This method has the advantages of relatively mild reaction conditions and high catalytic efficiency, but transition metal catalysts are relatively expensive, and cost factors and catalyst recovery and reuse need to be considered.
All synthesis methods have their own advantages and disadvantages. In practical applications, the most suitable synthesis route should be selected according to specific needs, such as raw material cost, product purity, reaction scale and other factors.
What are the precautions for the storage and transportation of 1,3-dimethyl-4-fluorobenzene?
The second reason is that the earth and the earth are made of water and mercury, and the earth and the earth are beautiful, and they contain the mystery of creation. When it comes to the existence of water and mercury, there is no need to pay more attention to it.
The first thing to know about it is also the tool of storage. Water mercury is soft and does not flow, and it is easy to attach to objects. Therefore, the tool of storage must have a dense gap to prevent leakage. The ancient good tools are mostly made of gold, gold, and gold. Because the ground is dense, it can retain the integrity of water and mercury. If pottery and porcelain are used, it is necessary to check the glaze, so that the glaze is thick and dense. If there is a slight omission, the water and mercury will escape, and it will not have its essence, and it may cause the surrounding environment to be polluted, which is harmful.
Second, the place where it is stored is also the place where it is stored. Mercury in water likes to be stored, and it is easy to be exposed to high temperatures. Inflammation, mercury in water is easy to steam, and it is easy to spread poison and endanger the human body. Therefore, the place where it is hidden, it is suitable to be hidden, and it is a remote and remote place, which is the source of fire and dryness. If it is hidden in a secret room, it is also often used, so that the poison can be dissipated, so as to protect the danger.
When it is in a secret room, its severity is even more severe. The flow of mercury in water is in a shape, and it is easy to overflow if it is slightly bumpy and inclined. In addition to fixing the secret device, it needs to be properly wrapped and fixed to prevent earthquakes and collisions. And those who are in trouble must be careful, and they must not be rushed. If you encounter any obstacles on the way, you should also be careful not to let the mercury in the water be released.
Furthermore, there needs to be a person to guard and take care of it. This person must be familiar with the nature of mercury in water and understand the way to prevent it. With a little regularity, he can observe it and take care of it properly. If there is any leakage, don't panic. Quickly cover it with sulfur powder to make it combine to dissolve its poison, and clean it up to avoid damage. In addition, the storage of mercury in water needs to be careful. If there is a little carelessness, you need to be careful. Only then can you preserve its essence and use it for future use.