Hongda Chemical
Products
Home  /  Products  / 

1,3-Dimethyl-2-Fluoro-4-Nitrobenzene

1,3-Dimethyl-2-Fluoro-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

875654

Chemical Formula C8H8FNO2
Molecular Weight 169.153
Appearance Solid (Typical)
Color Off - white to yellowish
Solubility In Water Insoluble (Estimated for aromatic nitro - compounds)
Logp Estimated to be relatively high due to aromatic and hydrophobic groups

As an accredited 1,3-Dimethyl-2-Fluoro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - dimethyl - 2 - fluoro - 4 - nitrobenzene packaged in a sealed glass bottle.
Storage 1,3 - dimethyl - 2 - fluoro - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions.
Shipping 1,3 - Dimethyl - 2 - fluoro - 4 - nitrobenzene, a chemical, is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous material regulations, ensuring safe transport to prevent spills and environmental or safety risks.
Free Quote

Competitive 1,3-Dimethyl-2-Fluoro-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1,3-Dimethyl-2-Fluoro-4-Nitrobenzene 1,3-Dimethyl-2-Fluoro-4-Nitrobenzene
General Information
Historical Development
1,3-Dimethyl-2-fluoro-4-nitrobenzene, the origin of this compound can be traced back to the past. At the beginning, the academic community did not explore fluorine-containing nitroaromatics in depth, and the road to synthesis was full of thorns. However, the wise men were not afraid, they worked hard and worked tirelessly.
After countless attempts, under specific conditions, and in an exquisite way, the reactants were cleverly combined to obtain this compound. When it was first obtained, its properties and uses were unknown, and it only existed in the laboratory.
With the passage of time, science and technology advanced, and scholars gained deeper insights into its structure and properties. It was found that it has great potential in the fields of materials science and drug research and development, like a pearl gradually shining, and has since embarked on a journey of extensive research and application, contributing to the development of many fields.
Product Overview
There is a substance named 1,3-dimethyl-2-fluoro-4-nitrobenzene. Its shape is also an organic compound with a unique structure. Looking at its molecules, dimethyl is based on the 1st and 3rd positions of the benzene ring, fluorine atoms are in the 2nd position, and nitro is in the 4th position. The color state of this compound is either solid or liquid at room temperature, depending on the environment. It is active and has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to make various fine chemicals, such as medicines, pesticides, dyes, etc. However, it has certain toxicity and danger. When using it, strict procedures should be followed to prevent harm to people and the environment. At the time of preparation, delicate methods are required to control the reaction conditions in order to obtain high-purity products, which are of great significance in chemical research and industrial production.
Physical & Chemical Properties
1,3-Dimethyl-2-fluoro-4-nitrobenzene, this compound is related to the study of physical and chemical properties of substances, which is quite important. Its physical properties, viewed at room temperature, are yellowish in color, like an oil, with a special odor. Its boiling point is quite high, about 200 degrees, due to the force between molecules. The melting point is relatively low, and it can be seen that it solidifies when placed in an ice bath.
When it comes to chemical properties, because of its fluorine, nitro and other groups, its reactivity is special. Nitro has strong electron absorption, which reduces the density of the electron cloud of the benzene ring, and the electrophilic substitution reaction is difficult. Although fluorine atoms are small, they have strong electronegativity, which affects the distribution of electron clouds of surrounding atoms. In the case of nucleophiles, the location of fluorine atoms may be substituted. The study of the physicochemical properties of this substance is of far-reaching significance in the fields of organic synthesis and drug development.
Technical Specifications & Labeling
1,3-Dimethyl-2-fluoro-4-nitrobenzene is also an organic compound. To clarify its technical specifications and identification (commodity parameters), it is necessary to study it with scientific methods.
Looking at this compound, its molecular structure is established, and precise steps need to be followed in the process of synthesis. The choice of raw materials must be pure and good, and the reaction conditions, such as temperature, pressure, catalyst, etc., must be carefully regulated.
As for the identification, its name already states the importance of the structure. Among the commodity parameters, purity is a crucial item, and its height must be required. The amount of impurities should be strictly controlled. Physical parameters such as melting point and density are also the key to identification and can be used as evidence for identifying this item. On the package, its name, structure, parameters, etc. should be clearly stated to ensure safe and accurate use. In this way, it can be used properly in research and production.
Preparation Method
To make 1,3-dimethyl-2-fluoro-4-nitrobenzene, the method is as follows: Prepare the raw materials first, select xylene, fluoride, nitro agent, etc., which must be pure and suitable. To make it, first put xylene into the kettle, control the temperature moderately, and slowly inject fluoride, which should be stable and orderly. When the fluorine is replaced, lower its temperature, and gradually add the nitro agent. Every step should be carefully observed, the temperature should be adjusted and the speed should be adjusted. After completion, fractionation and extraction techniques are used to remove heterogeneous and deposit sperm. And a check and balance mechanism is set up, each step is tested, and if it does not match, it will be changed, so that the pure quality of the product can be improved and used accurately. In this way, a well-prepared 1,3-dimethyl-2-fluoro-4-nitrobenzene can be obtained.
Chemical Reactions & Modifications
The transformation of 1,3-dimethyl-2-fluoro-4-nitrobenzene is also related to the transformation and quality transition. In the past, many people studied the theory of transformation, hoping for subtle methods to change its properties and increase its usefulness.
The transformation of this compound should, or the ease of involving groups, check the change of points. Fluorine, nitro and other groups, on the benzene ring, the fabric of the electron cloud and the structure of the space, all affect the direction and speed of the reaction. If you want to change its properties, think about how to adjust the position of the group and change the potential of its action.
Or you can try the method of catalysis to lead it along the way. Select a good agent, control temperature and pressure, and hope to promote its corresponding improvement. Or with the help of external fields such as light and electricity, we can open up new ways to respond, so that the row and bond of molecules can be changed differently. In the wonderful way of chemical application, we will study it unremitting, and hope to obtain the mystery of chemical transformation, which is the progress of 1,3-dimethyl-2-fluoro-4-nitrobenzene, and expand the endless domain.
Synonyms & Product Names
Today there is a thing called 1,3-dimethyl-2-fluoro-4-nitrobenzene. This thing has a wide range of uses in the field of chemistry. However, although its name is fixed, there are many other names, such as synonyms and trade names, which are known to everyone.
Its synonyms are due to the research and records of different students, or according to its structural characteristics, or according to its reaction characteristics. As for the trade name, it is related to the operation and promotion of the merchant, and varies according to market demand.
Although the names are different, their essence is the same. All are 1,3-dimethyl-2-fluoro-4-nitrobenzene. For our chemical researchers, it is necessary to clarify their many terms in order to navigate the academic and practical journey without confusion, and to achieve the accuracy and depth of their research.
Safety & Operational Standards
1,3-Dimethyl-2-fluoro-4-nitrobenzene, this chemical substance is related to safety and operation standards, and is extremely important and should not be ignored.
If you want to make this substance, you must first explain its properties. 1,3-Dimethyl-2-fluoro-4-nitrobenzene is dangerous. It is active and may explode in case of heat, open flame or strong oxidant. Therefore, when storing, it must be placed in a cool and ventilated place, away from fire and heat sources. And it must be separated from oxidants and food chemicals. Do not mix storage to prevent accidental changes.
As for the operation, all norms must also be strictly observed. Operators must be professionally trained and familiar with the operating procedures. The operation room should be equipped with good ventilation to ensure air circulation. When operating, you must wear appropriate protective clothing, protective gloves and goggles to prevent it from coming into contact with the skin and eyes. If you accidentally touch the skin, you should quickly rinse with a large amount of flowing water; if it enters the eyes, immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention immediately.
Furthermore, during the use of this chemical, smoking and eating are strictly prohibited. After the operation, you should also shower and change clothes in time, store the contaminated clothes separately, and wash them before use.
In short, the safety and operation specifications of 1,3-dimethyl-2-fluoro-4-nitrobenzene are the key to ensuring personal safety and environmental safety. They must be taken lightly and must be followed.
Application Area
1,3-Dimethyl-2-fluoro-4-nitrobenzene, this compound is used in many fields. In the field of pharmaceutical development, it can be used as a key intermediate to help synthesize pharmaceutical components with special curative effects. By precisely regulating its molecular structure, it may be able to develop highly effective drugs for specific diseases. In the field of materials science, due to its unique chemical properties, it may be involved in the preparation of new functional materials, such as materials with special optical and electrical properties, to meet the specific needs of electronic equipment, optical instruments and other industries. In the field of organic synthesis, as an important starting material, it can build complex organic molecular structures through various chemical reactions, expand the types and functions of organic compounds, and open up broader avenues for chemical research and industrial production.
Research & Development
In recent years, Yu dedicated himself to the research of 1,3-dimethyl-2-fluoro-4-nitrobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path and encountered difficulties frequently. The ratio of raw materials and reaction conditions are slightly poor, so it is difficult to obtain the ideal product. However, I did not give up, and repeatedly deduced the method recorded in ancient books, combined with the current new theory, and finally found the optimization method. The yield gradually increases, and the purity of the product reaches a quite high level.
At the same time, study its reaction mechanism and gain insight into the influence of various factors. After repeated experiments, the relationship between its structure and properties is clarified. This research paves the way for its wider application. In the future, it is expected to shine in the fields of medicine, materials, etc., promote the development of the industry, and contribute to my generation's chemical research.
Toxicity Research
In recent years, I have focused on the toxicity study of 1,3-dimethyl-2-fluoro-4-nitrobenzene. This compound is increasingly used in industry, but its potential harm has not been investigated in detail.
Looking at its molecular structure, the substitution of fluorine and nitro groups makes the chemical activity different. The experiment was carried out on white mice fed with food containing this substance. After ten months, the behavior of the white mice was normal, the eating and activity gradually slowed down, and the hair lost its luster. From the dissection, the organs were abnormal, the liver was uneven in color, and the kidneys were slightly swollen. These are all signs of toxic invasion.
It was proved by cell experiments that when the cultured cells encountered this substance, the growth was inhibited, the division was disordered, and some cells were apoptotic. It can be seen that this substance is very harmful to biological physiology. Although the research has not been completed, it has been proved that it has significant toxicity. In the future, when used in industry, one should be careful to prevent it from escaping, so as not to cause harm to life.
Future Prospects
Today there is a thing called 1,3-dimethyl-2-fluoro-4-nitrobenzene, which I studied in my room. Thinking about its future, I look forward to it. Although this thing is small, it has a wide range of uses. It can be used in various chemical processes, or as a raw material for medicine, or as an auxiliary agent for dyeing.
I hope that in the future, it can shine in the field of medicine. Help doctors make good medicines, relieve people's pain. I also hope to emerge in the world of materials, making utensils stronger and more beautiful. Although there may be thorns in the road ahead, I firmly believe that with time and careful study, I will be able to show my ability. At that time, this 1,3-dimethyl-2-fluoro-4-nitrobenzene will surely be able to contribute to the progress of the world and become our unfinished ambition.
Where to Buy 1,3-Dimethyl-2-Fluoro-4-Nitrobenzene in China?
As a trusted 1,3-Dimethyl-2-Fluoro-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dimethyl-2-Fluoro-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1,3-dimethyl-2-fluoro-4-nitrobenzene?
1% 2C3-dimethyl-2-pentene-4-alkynylbenzene, which is an organic compound. Its physical properties are as follows:
Looking at its morphology, it is mostly liquid at room temperature and pressure. Due to the characteristics of carbon chain length and unsaturated bonds in the molecular structure, the intermolecular force is not strong enough to maintain the solid state.
When it comes to color, pure 1% 2C3-dimethyl-2-pentene-4-alkynylbenzene may be colorless and transparent. However, if it contains impurities, the color may change, such as the incorporation of some impurities, or cause it to appear slightly yellow.
Smell its odor, with a special organic odor. This odor originates from its complex molecular structure, the existence of unsaturated bonds and benzene rings, giving it unique volatility and odor characteristics.
As for solubility, since it is an organic compound, it follows the principle of similar compatibility and can be soluble in many organic solvents, such as ether, chloroform, benzene, etc. The intermolecular forces between the edge organic solvent and the compound are similar and can be mixed with each other. However, it is difficult to dissolve in water. Because water is a polar solvent, and 1% 2C3-dimethyl-2-pentene-4-alkynylbenzene has a weak molecular polarity, the forces between the two molecules are quite different, so it is not easy to miscible.
In terms of boiling point, due to the existence of double bonds and triple bonds in the molecule, the interaction between molecules increases, and the boiling point is higher than that of saturated hydrocarbons with the same number of carbon atoms. The specific boiling point value is determined by factors such as the exact geometry of the molecular structure and the relative molecular weight.
The melting point is also affected by the molecular structure. The rigid structure of the unsaturated bond and the benzene ring makes the molecular arrangement more orderly, which in turn affects the melting point. Generally speaking, the melting point is within a certain range, but the exact value needs to be determined experimentally and accurately.
In terms of density, it is smaller than that of water. Due to the structure of carbon and hydrogen atoms in the molecule, its relative density is lower than that of the close arrangement structure of water molecules.
What are the chemical properties of 1,3-dimethyl-2-fluoro-4-nitrobenzene
1% 2C3-dimethyl-2-ene-4-carbonylthiophene. The chemical properties of this substance are as follows:
First, its molecular structure contains carbon-carbon double bonds, which are typical of olefins. Addition reactions can occur, such as addition with halogens (chlorine, bromine, etc.) to form halogenated hydrocarbons. In case of bromine water, bromine water fades, and due to the opening of the double bond, bromine atoms are added to the carbon at both ends of the double bond. This is a commonly used method for identifying olefins. It can also be added with hydrogen under the action of a catalyst to form saturated thiophene derivatives. This reaction can be used to prepare compounds with specific structures.
Furthermore, the intra-molecular carbonyl group has the characteristics of aldehyde and ketone. It can react with nucleophilic reagents, such as with alcohols under acidic conditions to form acetals or ketals. The presence of carbonyl groups makes the molecule have a certain polarity and affects its physical properties, such as boiling point and solubility. Because it can form hydrogen bonds with water molecules, it has a certain solubility in water.
In addition, the thiophene ring imparts special electronic properties to the compound. The thiophene ring is an electron-rich aromatic ring, which is prone to electrophilic substitution reaction, and the substitution check point is affected by other groups on the ring. Methyl is the power supply radical, which can increase the electron cloud density of the benzene ring, and is more prone to electrophilic substitution. And the localization effect makes the substituent mainly enter the methyl ortho and para-position.
This compound is chemically active and has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to construct complex organic molecular structures through a series of reactions, and is used in the research and production of drugs, materials and many other fields.
What are the main uses of 1,3-dimethyl-2-fluoro-4-nitrobenzene?
1% 2C3 + - + dimethyl-2-ene-4-carbonyl pyridine is a crucial compound in the field of organic synthesis and is widely used in many fields. The following details its main uses:
First, in the field of medicinal chemistry, this compound is often used as a key intermediate for the synthesis of drug molecules with specific biological activities. Due to its unique chemical structure, it can participate in a variety of chemical reactions. After ingenious design and modification, it is expected to construct drugs with high affinity and selectivity for specific disease targets. For example, in the development of anti-tumor drugs, through structural modification, new drugs that can effectively inhibit tumor cell proliferation and induce tumor cell apoptosis may be obtained; in the development of antibacterial drugs, drugs with strong inhibitory effect on specific pathogens can also be prepared through reasonable modification.
Second, in the field of materials science, 1% 2C3 + - + dimethyl-2-ene-4-carbonyl pyridine can be used to prepare functional materials. Because of its specific electronic structure and chemical properties, it can endow materials with unique optical, electrical or magnetic properties. For example, in organic optoelectronic materials, it can be used as an important building unit to improve the charge transfer efficiency and luminous efficiency of the material, and help develop better organic light emitting diodes (OLEDs), solar cells and other optoelectronic devices.
Third, in the field of organic synthetic chemistry, this compound is often used as a multifunctional synthesizer. With its double bonds, carbonyl groups and other active functional groups, various chemical reactions such as addition, substitution, and cyclization can occur, providing an effective way to construct complex organic molecular structures. Organic chemists can flexibly use this compound according to the structural requirements of the target product to design efficient synthesis routes and realize the total synthesis of complex natural products or organic compounds with special functions.
What are the synthesis methods of 1,3-dimethyl-2-fluoro-4-nitrobenzene
There are many synthesis methods of 1% 2C3-dimethyl-2-pentene-4-alkynylbenzene, and the following are the main ones.
One is the alkyne coupling method. The intermediate containing alkynyl groups is first prepared, and the coupling reaction with alkenyl and aryl-containing halogens or other electrophilic reagents occurs with suitable catalysts, such as palladium, copper and other catalytic systems. In this process, the control of catalyst activity and reaction conditions is critical. In a suitable solvent, such as dimethylformamide (DMF) or tetrahydrofuran (THF), at a certain temperature and in the presence of a base, the alkynyl carbons of alkynes react with electrophilic reagents to gradually build the carbon backbone of the target molecule to obtain 1% 2C3-dimethyl-2-pentene-4-alkynylbenzene.
The second is the alkenylation reaction path. First prepare the benzene derivative containing alkynyl groups, and then use the alkenylation reagent to carry out the alkenylation reaction under specific conditions. Transition metal-catalyzed alkenylation reactions, such as Heck reaction, Negishi reaction, etc., can be selected. Taking the Heck reaction as an example, under the action of palladium catalyst, ligand and base, halogenated olefins react with phenyne derivatives to form carbon-carbon double bonds and realize alkenylation. The configuration of the double bond and the position of the substituent can be controlled by adjusting the substrate structure and reaction conditions, so as to achieve the synthesis of 1% 2C3-dimethyl-2-pentene-4-alkynylbenzene.
The third is a multi-step reaction construction method. First, the structural fragments containing alkenyl and alkynyl groups are constructed by multi-step reaction, and then the two are connected by suitable reactions. For example, aromatics are first used as starting materials, suitable substituents are introduced through substitution reactions to construct alkenyl-containing fragments, and then alkynyl-containing fragments are introduced through alkynylation reactions. Finally, carbon-carbon bond formation reactions, such as Sonogashira reactions, connect alkenyl groups to alkynyl-based fragments, and after appropriate post-treatment, the target product 1% 2C3-dimethyl-2-pentene-4-alkynylbenzene can be obtained.
Each synthesis method has its own advantages and disadvantages. In practical application, it is necessary to comprehensively consider various factors such as the availability of raw materials, the difficulty of reaction conditions, yield and selectivity, and choose the most suitable method.
What are the precautions for storing and transporting 1,3-dimethyl-2-fluoro-4-nitrobenzene?
1% 2C3-dimethyl-2-ene-4-carbonylbenzene should pay attention to the following matters during storage and transportation:
First, when storing, it should be placed in a cool and dry place. This substance is prone to chemical reactions in case of moisture, resulting in damage to its quality. If the environment is humid, water vapor or interacts with the active groups in the substance, triggering reactions such as hydrolysis, changing its chemical structure and properties. For example, many compounds containing carbonyl groups are easy to absorb water in humid environments, affecting purity and stability.
Second, temperature control is crucial. Avoid high temperature, because high temperature will promote its volatilization or accelerate chemical reactions. Under high temperature, the molecular movement intensifies and the reactivity is enhanced, which may trigger reactions such as decomposition and polymerization. When the alkene compound is at high temperature, the double bond is prone to changes such as addition and polymerization, which affects the original properties of the substance.
Third, the storage place should be well ventilated. To prevent the accumulation of its volatile gases, otherwise once it reaches a certain concentration, it may encounter open fire or static electricity, etc., and there is a risk of explosion. Many volatile gases of organic compounds are flammable, and good ventilation can reduce the risk.
Fourth, during transportation, the packaging must be strong and tight. To prevent the package from being damaged due to collision and vibration, and the material leaks. Packaging materials should have good pressure resistance, shock resistance and anti-penetration properties.
Fifth, it should be stored and transported separately from oxidants, acids, bases and other substances. Due to its active chemical properties, contact with these substances can easily cause violent chemical reactions and even explosions. For example, when carbonyl compounds come into contact with acids and bases, reactions such as hydrolysis and condensation may occur.
Sixth, transportation and storage personnel need to undergo professional training. Familiar with the characteristics, hazards and emergency treatment methods of the substance, so as to properly respond to and reduce hazards in case of emergencies.