1,3-Dimethoxy-5-Fluorobenzene

Hongda Chemical

Specifications

HS Code	990738
Chemical Formula	C8H9FO2
Molar Mass	156.154 g/mol
Appearance	Typically a colorless to light - colored liquid or solid (depending on conditions)
Boiling Point	Data may vary, but generally in a certain temperature range related to its molecular structure
Melting Point	Specific melting point value determined by its intermolecular forces
Density	Characteristic density value based on its mass - volume relationship
Solubility In Water	Low solubility as it is an organic compound with non - polar aromatic and methoxy groups
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, dichloromethane etc.
Flash Point	Value indicating the temperature at which it can form a flammable vapor - air mixture
Vapor Pressure	Pressure exerted by its vapor in equilibrium with the liquid phase at a given temperature

As an accredited 1,3-Dimethoxy-5-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1,3 - dimethoxy - 5 - fluorobenzene packaged in a sealed, chemical - resistant bottle.
Storage	1,3 - Dimethoxy - 5 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. Follow proper labeling and safety protocols for easy identification and handling.
Shipping	1,3 - Dimethoxy - 5 - fluorobenzene is shipped in well - sealed containers, compliant with chemical transport regulations. Packaging safeguards against leakage, and shipping is arranged with carriers experienced in handling such chemicals to ensure safe transit.

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General Information

Historical Development

The origin of 1,3-dimethoxy-5-fluorobenzene can be traced back to the past. At the beginning, all the sages studied and explored in the field of chemistry, and gradually touched this thing. At that time, the conditions were difficult, the equipment was simple and clumsy, but the determined ones were fearless and difficult, and they worked tirelessly.
After several generations of sages and talents, the technology has evolved and the cognition has deepened. From the initial ignorance and exploration, to the clarification of its nature and the method of its synthesis, it has been difficult step by step. In the past, there was a lack of information, and everyone relied on persistence and wisdom to find its traces in the vast sea of knowledge.
Today, 1,3-dimethoxy-5-fluorobenzene is increasingly used in the chemical industry. Looking back on the road of development in the past, it is like a long march, condensing the efforts of countless talents, and finally shining in the forest of chemistry, paving the way for more exploration in future generations.

Product Overview

1,3-Dimethoxy-5-fluorobenzene is also an organic compound. It has unique properties and is widely used in various fields of chemistry. Looking at its structure, fluorine atoms and dimethoxy groups coexist on the benzene ring, resulting in unique physical and chemical properties.
This compound is either liquid or solid at room temperature, and its color state varies according to its purity and environment. Its physical constants such as boiling point and melting point depend on the interactions within the molecule, which can be used for separation and purification.
Chemically, due to the high electronegativity of fluorine atoms, the electron cloud density distribution of benzene ring is different, which makes it exhibit special activity and selectivity in reactions such as electrophilic substitution. Dimethoxy also affects its reactivity, either assisting or inhibiting the progress of the reaction.
In the field of organic synthesis, 1,3-dimethoxy-5-fluorobenzene is often a key intermediate. It can be prepared by various paths, and each method has advantages and disadvantages. The products derived from it also have potential value in the pharmaceutical, pesticide, material and other industries, and need to be further explored by researchers to make the best use of them.

Physical & Chemical Properties

1,3-Dimethoxy-5-fluorobenzene has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless and transparent liquid with a clear texture, similar to the water of Mirror Lake. Its smell is elegant, slightly fragrant, not pungent and strong. The boiling point is quite high, about a certain temperature, which makes it difficult to evaporate and dissipate in ordinary environments. Regarding its chemistry, the presence of fluorine atoms in the molecular structure gives it special chemical activity. When it reacts with other substances, or due to the electronic effect of methoxy groups, the reaction path is slightly different from that of ordinary benzene derivatives. And because of its stable structure, it has a certain degree of resistance to change in common chemical environments, and is not easy to decompose without reason. It is like a solid fortress, keeping its essence unchanged, so that it can play a unique role in the field of chemistry.

Technical Specifications & Labeling

Technical specification and identification of 1,3-dimethoxy-5-fluorobenzene (product parameters)
Fu 1,3-dimethoxy-5-fluorobenzene is also the chemical I am researching. Its technical regulations are related to the synthesis method. First take an appropriate amount of starting materials and put them into the reactor according to the precise ratio. Control with appropriate temperature, pressure, and a specific catalyst to make it fully react. During this period, the reaction process must be strictly observed, and various parameters must be adjusted to ensure a smooth reaction.
As for the label, the name of the product should be "1,3-dimethoxy-5-fluorobenzene", with chemical formula, molecular weight and other parameters. On the package, a warning label should be marked to indicate its physical and chemical properties and safety instructions to prevent misuse. And detailed storage conditions should be placed in a cool, dry place to avoid mixing with strong oxidants, acids, etc., to ensure the quality and safety of the product.

Preparation Method

The method of making 1,3-dimethoxy-5-fluorobenzene is the first raw material. Fluorobenzene, dimethyl sulfate, etc. need to be prepared as substances. The preparation process involves first placing fluorobenzene in the reaction kettle, adding an appropriate amount of catalyst, controlling the temperature to an appropriate level, and gradually injecting dimethyl sulfate. This reaction requires careful observation of temperature and reaction process to prevent side reactions. After the reaction is completed, the product is purified by distillation and extraction.
During distillation, fractionate according to the different boiling points of each substance to obtain the crude product. During extraction, select the appropriate solvent to extract the target substance. After further distillation, impurity removal and purification, the final pure product 1,3-dimethoxy-5-fluorobenzene is obtained. The whole process, temperature control, time control and anti-impurities mixing is necessary, so as to obtain good quality products.

Chemical Reactions & Modifications

The reaction and change of 1,3-dimethoxy-5-fluorobenzene are related to the wonders of chemistry and cannot be ignored.
Initially, the reaction of this compound, or according to the usual method, then want to change its chemical properties in order to achieve a new environment. In the way of the reaction, all conditions must be well adjusted. Temperature and solvent are the main factors. If the temperature is high, the reaction speed may be caused, and if the temperature is low, it may be slow and not reached. The nature of the solvent also affects the direction of the reaction.
We try to introduce a new agent and observe its change. Or the selectivity of the reaction can be increased and the yield also rises. And if you want to change its chemical properties, you can fine-tune the structure, introduce new groups, and explore the change of its activity.
During the
period, various methods were used to make the chemical reaction of 1,3-dimethoxy-5-fluorobenzene have a different appearance, adding new color to the research of chemistry.

Synonyms & Product Names

There is a recent product named 1,3-dimethoxy-5-fluorobenzene, which has attracted much attention in our chemical research. The synonyms and trade names of this product are also the focus of investigation.
The synonyms of husband are those that refer to more than one thing, or because of different regions, habits, or academic history, the same substance is often referred to as one thing. As for the trade name, merchants have established a separate name in order to recognize its characteristics and promote sales.
The synonyms of 1,3-dimethoxy-5-fluorobenzene are either derived from the other names of its chemical structure or derived from the old naming system. The name of the product depends on its use, quality and other characteristics, which are determined by the businessperson's ingenuity. On the occasion of research, it is helpful to distinguish its synonyms and trade names, which is helpful for accurate communication and mastery of its characteristics, and is also important to promote the progress of chemical research.

Safety & Operational Standards

For 1,3-dimethoxy-5-fluorobenzene, it is also a kind of chemical preparation. It is really something that our researchers should pay close attention to when it comes to the safety and operation specifications of this thing.
Before taking it, its physical properties must be carefully inspected. 1,3-dimethoxy-5-fluorobenzene has special chemical properties, and it may be different from others. In storage regulations, when looking for a cool, dry and well-ventilated place, avoid co-storage with strong oxidation and strong reduction to prevent unexpected changes. The reservoir also needs to be carefully selected to keep the air tight and prevent its volatilization and leakage.
During operation, protective equipment is indispensable. It is advisable to wear professional laboratory clothes, wear chemical-resistant gloves, and goggles to prevent them from splashing on the body surface and eyes. Act in the fume hood so that the scattered gas can be dispersed in time, so as not to gather in the room and endanger the person.
If the operation is wrong, causing it to leak, do not panic. Cut off the fire source first to prevent the risk of explosion. For small leaks, you can cover them with inert substances such as sand and vermiculite and put them in a special device; when there is a large leak, quickly disperse others and set up a warning area, which will be disposed of by professionals in accordance with regulations.
Furthermore, after the experiment, the remaining materials and utensils need to be properly disposed of. The remaining materials should not be disposed of at will, and should be recycled or destroyed in accordance with regulations. The equipment needs to be cleaned to remove residues, so as not to affect the next experiment, and to ensure safety.
In short, the safety and operation specifications of 1,3-dimethoxy-5-fluorobenzene are the top priority throughout the research and use. We should strictly abide by it and not slack off.

Application Area

1,3-Dimethoxy-5-fluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help the development of many new drugs. Because of its unique chemical structure, it can participate in various reactions, paving the way for the synthesis of drug molecules with specific curative effects.
In the field of materials science, it also shows unique advantages. Through specific processes, new materials can be incorporated to improve the properties of materials, such as improving their stability, conductivity, etc., making materials more practical in electronic devices and other aspects.
In the field of fine chemicals, as an important raw material, it helps to synthesize high value-added fine chemicals, increases the quality and function of products, and contributes to the development of the fine chemical industry. From this point of view, 1,3-dimethoxy-5-fluorobenzene has an important position in various field applications and has broad prospects.

Research & Development

Today, there is a product called 1,3-dimethoxy-5-fluorobenzene, which is very important in our field of chemical research. We have dedicated ourselves to exploring its properties, preparation methods and various applications.
Looking at its structure, it is unique and exquisite, and this unique structure gives it a different chemical activity. We use a variety of experimental methods to observe its reaction under different conditions. After repeated trials, we gradually understand the best way of its synthesis, and strive to improve the yield and optimize the quality.
As for the application, the prospect is quite broad. It can be used to create new drugs to treat various diseases in the world; or it can emerge in the field of materials science, contributing to the research and development of new materials. We should make unremitting efforts and delve deeper into it, with the hope of expanding the boundaries of its application and making it contribute more to human well-being.

Toxicity Research

Those who try to study poisons need to be cautious. Today, there is 1,3-dimethoxy-5-fluorobenzene, and the research on its toxicity is related to everyone's safety.
When studying the toxicity of this substance, observe its physical and chemical properties in detail, and observe its response to other things. Test it by various methods, observe the effect of its entry into the body, and the impact on life and rest. It may cause damage to the viscera, disturb the luck of qi and blood, and disrupt the peace of mind.
However, the research on toxicity is not done overnight, and it must be accumulated in a few steps, and it will accumulate small streams. According to the scientific method, do it rigorously, and record the results in detail for future reference. With detailed research, it is hoped to clarify the mystery of its toxicity, provide evidence for the way of protection and use, and ensure the safety of all living beings and avoid the invasion of poison.

Future Prospects

1,3-Dimethoxy-5-fluorobenzene is also an organic compound. In today's field of chemical research, its emerging and promising prospects.
This compound, in a corner of material chemistry, or a fertile new material, has an exquisite structure and seems to have endless potential. Due to its characteristics, in the future in the field of electronic materials, it may be able to add new substances to the conductive medium, making the efficiency of electron conduction better, so that the device can be advanced.
In the field of pharmaceutical chemistry, there is also high hope. Its molecular configuration may be the basis for the creation of new drugs, targeting diseases and eliminating diseases. Or it can open up a new path in the research of anti-cancer drugs, and use precise effects to control the ravages of cancer cells.
In the genus of fragrance chemistry, or endow fragrances with unique fragrance, adding new color to the fragrant world. Although the current knowledge is not complete, its future development, such as the early rise of the morning sun, is full of hope, and will surely bloom in various fields and create a new situation.

Where to Buy 1,3-Dimethoxy-5-Fluorobenzene in China?

As a trusted 1,3-Dimethoxy-5-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1,3-Dimethoxy-5-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-dimethoxy-5-fluorobenzene?

1% 2C3-dimethoxy-5-fluorobenzene, although this substance is not directly mentioned in "Tiangongkai", it is widely used in the current era based on ancient chemical processes and medicinal knowledge.
In the field of medicine, this compound is often a key intermediate. Due to its unique chemical structure, the introduction of fluorine atoms endows the molecule with specific biological activity and stability. Pharmaceuticals use this to synthesize many drugs or act on specific targets to treat diseases. For example, the development of some anti-cancer drugs uses their structural properties to precisely attack cancer cells and improve their efficacy.
In the field of materials science, it also has extraordinary performance. With its own chemical properties, it can participate in the synthesis of polymer materials and improve material properties. Or enhance the material's heat resistance and chemical corrosion resistance, so that the material remains stable in extreme environments, and is widely used in high-end fields such as aerospace and electronic equipment manufacturing.
Although this material is not included in "Tiangong Kaiwu", looking at the current scientific development, 1% 2C3-dimethoxy-5-fluorobenzene has a significant position in the field of medicine and materials, and has made great contributions to promoting modern scientific and technological progress.

What are the physical properties of 1,3-dimethoxy-5-fluorobenzene?

1,3-Dimethoxy-5-ethylbenzene is a synthetic organic compound. Its physical properties are as follows:
Under normal conditions, this compound is mostly a colorless to light yellow transparent liquid, clear and free of impurities. Under light, it can be seen that its surface refracts a soft light.
Smell it, it has a special aromatic smell. This smell is not pungent and evil, but it is not as pleasant as common flowers. It is a unique organic aromatic smell. If smelled for a long time, it may cause discomfort.
When it comes to volatility, it has a certain volatility due to the characteristics of its molecular structure. Under normal temperature and pressure, it can evaporate slowly into the surrounding air. Although the volatilization rate is not extremely fast, if it is placed in an open space and the time is slightly longer, its amount will also be reduced.
The boiling point has been determined by many Fangjia experiments and is within a certain temperature range. The value of this boiling point makes it change from liquid to gaseous under specific temperature conditions. When heated to near the boiling point, bubbles begin to form inside the liquid, which then tumble violently, and eventually all vaporize.
In terms of solubility, 1,3-dimethoxy-5-ethylbenzene is insoluble in water. The polarity of water is very different from the non-polar structure of this compound, just like oil and water, the two are difficult to blend. However, it is soluble in a variety of organic solvents, such as ethanol, ether, etc. In organic solvents, it can be uniformly dispersed to form a uniform solution system. This property makes it possible to achieve dissolution and separation processes with the help of organic solvents in organic synthesis and related chemical operations.
The density is slightly smaller than that of water. If it is placed in the same container as water, it can be seen that it floats on the water surface. The two layers are clearly delineated and the boundaries are distinct. This is due to the difference in density between the two.

Is the chemical properties of 1,3-dimethoxy-5-fluorobenzene stable?

The chemical properties of 1% 2C3-dimethoxy-5-fluorobenzene are quite stable under normal conditions. In this compound, the structure of the benzene ring endows it with a certain degree of stability. Because the benzene ring has a conjugated system, the electron cloud distribution is relatively uniform, which reduces the molecular energy and improves the stability.
methyl is connected to the benzene ring, and methyl is the power supply subgroup, which can provide electrons to the benzene ring through induction effect and superconjugation effect, which in turn affects the electron cloud density distribution of the benzene ring and enhances the stability of the molecule to a certain extent. The methoxy group is also the power supply subgroup. When it is connected to the benzene ring, it can increase the electron cloud density of the benzene ring through the conjugation effect, which Furthermore, although fluorine atoms have strong electron-withdrawing properties, when they are connected to the benzene ring, they will form p-π conjugation with the benzene ring due to the lone pair electrons of the fluorine atom, which also stabilizes the molecular structure to a certain extent.
However, this stability is not absolute. Under specific reaction conditions, in case of extreme environments such as strong oxidants, strong acids, strong bases or high temperatures, its chemical properties will also change. For example, under the action of strong oxidants, methyl or methoxy groups may be oxidized; in strong acid environments, methoxy groups may undergo reactions such as protonation, which in turn affects the structure and stability of the entire molecule. However, in the normal storage and general chemical operating environment, the chemical properties of 1% 2C3-dimethoxy-5-fluorobenzene are relatively stable, and it can maintain a relatively stable state without significant chemical changes.

What are the preparation methods of 1,3-dimethoxy-5-fluorobenzene?

The preparation method of 1% 2C3-diethoxy-5-bromobenzene is not directly described in "Tiangong Kaizi", but the ancient principles contained in the book on chemical and pharmaceutical industries may be used to deduce the preparation ideas of this substance.
Preparation of such organic compounds in the past, or take the raw materials containing benzene rings first, such as benzene as the beginning. Benzene is active in nature and can be introduced into bromine atoms by substitution reaction. Because the bromination reaction can be catalyzed by iron or iron tribromide, bromine and benzene react. Put benzene and an appropriate amount of liquid bromine in the reactor, and use iron filings as the catalyst, bromine atoms can replace the hydrogen on the benzene ring to generate bromobenzene. This step requires temperature control, because the temperature affects the substitution position and the purity of the product.
After obtaining bromobenzene, ethoxy is introduced, or nucleophilic substitution can be used. In the traditional method, ethanol is reacted with sodium metal to obtain sodium ethanol, which has strong nucleophilicity. Bromobenzene and sodium ethanol are mixed in a suitable solvent (such as anhydrous ethyl ether or toluene) and heated to reflux. The ethoxy negative ions in sodium ethanol attack the phenyl ring of bromobenzene, and the bromine ions leave, resulting in a precursor of 1% 2C3-diethoxy-5-bromobenzene. However, this process requires attention to the reaction conditions, and the anhydrous environment is very critical, because water reacts with sodium ethanol to reduce the concentration of nucleophilic reagents.
Or there are those who use natural products as starting materials. For example, in some plant extracts or components containing benzene rings and modifiable groups, after separation and purification, ethoxy and bromine atoms are gradually introduced by hydrolysis, esterification and other reactions. However, this approach requires a good understanding of the chemical properties of natural products, and the separation and purification steps are complicated, which requires quite high technical requirements.
In the preparation process, the ancients may also pay attention to the separation and purification of the product. Or use distillation to separate by using the difference in boiling points of each substance; or use recrystallization to select a suitable solvent to crystallize and precipitate the product in it for the purpose of purification.

What is the price range of 1,3-dimethoxy-5-fluorobenzene in the market?

1% 2C3-dimethoxy-5-chlorobenzene is in the market, and its price is variable. Due to the different market conditions, changes in supply and demand, difficulties in production, and differences in quality can all make the price different.
In the past, if the supply of this product exceeds the demand and the city is full, its price will be cheap, or it can be as low as several dollars per catty. Gai merchants want to sell inventory quickly and compete to reduce prices to win the favor of buyers.
However, if there is a surge in demand, and the production system is not enough, or the raw materials are scarce and the production is difficult, the price will rise. At that time, it was unknown how much it cost per catty.
The quality of the product is also the main reason. High purity, rare impurities of 1% 2C3-dimethoxy-5-chlorobenzene, the price must be higher than that of regular products. Because of its use in various things, such as medicinal stone refining, wonderful color dyeing, and better efficacy, buyers are willing to pay more for it.
And in four places, the price is also different. Prosperous capital, business travel converges, the flow of things is convenient, and the price is flat; while in remote areas, transshipment is difficult, and the price is high.
is because in order to know the exact price of 1% 2C3-dimethoxy-5-chlorobenzene, it is necessary to carefully observe the supply and demand of the city, examine its quality, and measure its location.