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1,3-Difluoro-5-(Trifluoromethyl)Benzene

1,3-Difluoro-5-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    715151

    Chemical Formula C7H3F5
    Molar Mass 182.09 g/mol
    Appearance Colorless liquid
    Boiling Point Around 110 - 112 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene

    As an accredited 1,3-Difluoro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,3 - difluoro - 5 - (trifluoromethyl)benzene in 500 - mL glass bottle, one per package.
    Storage 1,3 - Difluoro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of materials resistant to chemical corrosion, like stainless steel or certain plastics, to prevent leakage and maintain its chemical integrity.
    Shipping 1,3 - difluoro - 5 - (trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. Special care is taken to ensure compliance with hazardous chemical shipping regulations, with proper labeling for safe transportation.
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    1,3-Difluoro-5-(Trifluoromethyl)Benzene 1,3-Difluoro-5-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1,3-Difluoro-5- (trifluoromethyl) benzene is also an organic compound. At the beginning, various sages studied and searched in the field of chemistry, hoping to obtain this new substance. In the past, the way of chemistry was not as clear as it is today. With perseverance and wisdom, everyone used trial and error methods and research states to explore the secrets of material synthesis.
    At the beginning, it was difficult to obtain this compound. The preparation of raw materials and the control of reactions are all difficult problems. However, scholars were not discouraged and tried repeatedly for many years. Or because the conditions were not in line, the reaction was fruitless; or because the impurities were difficult to remove, the product was impure. However, his ambition became stronger and he kept exploring.
    After a long time of study, I gradually realized the reaction conditions, and the ratio of raw materials and temperature can be accurately grasped. Therefore, the preparation of 1,3-difluoro-5- (trifluoromethyl) benzene has gradually become. Since its birth, it has gradually shown its use in the fields of medicine and materials, adding a brilliant chapter to the development of chemistry.
    Product Overview
    1,3-Difluoro-5- (trifluoromethyl) benzene is also an organic compound. Its color is pure and pure, and it has unique chemical properties. Looking at its structure, fluorine and trifluoromethyl are ingeniously linked, and on the benzene ring, the structure is exquisite. The melting and boiling point of this compound is specific, and it is stable in its state under a specific temperature and pressure.
    It is active and often involved in various chemical reactions. In the field of organic synthesis, it is a key raw material. It can combine with many reagents to make novel compounds, and has a wide range of uses. Or it is used to create high-efficiency drugs and help the development of medicine; or it is involved in material research and development to give materials specific properties.
    The preparation of this compound requires precise control of the reaction conditions, and the proportion of raw materials, temperature, and duration are all key. Only with precise operation can high-purity products be obtained. Its position in the process of chemical research is significant, and it is also a tool for researchers to explore the unknown and open up new horizons.
    Physical & Chemical Properties
    1,3-Difluoro-5- (trifluoromethyl) benzene is also an organic compound. Its physical properties are colorless liquids at room temperature, with a special odor. The boiling point is moderate, about a certain value, because it can be measured. Its density is lighter than water, floating on water. In terms of solubility, it is slightly soluble in water, but it is quite soluble in organic solvents, such as alcohols and ethers.
    In terms of its chemical properties, the structure of the benzene ring gives it a certain stability. The existence of fluorine atoms and trifluoromethyl groups causes the distribution of its electron cloud to be different, which affects its reactivity. It can react with nucleophilic reagents and electrophilic reagents, and due to the characteristics of its substituents, the reaction check points and paths are regular. In the field of organic synthesis, it is an important raw material. It can construct many complex compounds through specific reactions to meet the needs of various industries such as medicine and materials.
    Technical Specifications & Labeling
    1,3-Difluoro-5- (trifluoromethyl) benzene, this chemical substance, its technical specifications and identification (product parameters) are the key. Looking at its physical properties, it is a colorless liquid with a special atmosphere and is widely used in various fields of chemical industry.
    On its technical specifications, the purity must be above 99%, and the impurity content must be strictly controlled. Its boiling point, melting point and other parameters are also accurately defined, which is related to product quality and application effectiveness.
    In terms of labeling, on the packaging, clearly mark the name, molecular formula, warning language, etc. The warning statement indicates that it has certain hazards, such as flammability, irritation, etc., to prevent inadvertent use.
    To prepare this substance, the process is complicated, and the reaction conditions need to be carefully controlled in order to obtain high-quality 1,3-difluoro-5- (trifluoromethyl) benzene to meet the needs of all parties.
    Preparation Method
    1,3-Difluoro-5- (trifluoromethyl) benzene is also an organic compound. The method of its preparation is related to the raw materials and production process, reaction steps, and catalytic mechanism.
    To prepare this product, appropriate raw materials must be prepared first. Select a compound containing fluorine and methyl, and mix it in the reactor according to a specific ratio. Add a suitable catalyst, this catalyst can increase the reaction speed and increase its yield. Set the conditions of temperature and pressure to make the reaction proceed smoothly.
    Initially, the raw materials are combined with each other under the action of the catalyst to form an intermediate product. Then, after several steps of reaction, it is gradually converted. Each step of the reaction requires precise temperature control and pressure control to check the progress of the reaction.
    After the reaction is completed, the impurities are removed through the separation and purification process to obtain pure 1,3-difluoro-5- (trifluoromethyl) benzene. The preparation process is complicated, and each link needs to be carefully controlled to achieve the desired effect.
    Chemical Reactions & Modifications
    There is now a product named 1,3-difluoro-5- (trifluoromethyl) benzene. In the field of chemistry, its reaction and modification are crucial.
    Looking at its reaction, when it encounters various reagents, it often produces wonderful changes. Or due to the characteristics of the bond, under specific conditions, the fluorine atom is active, easy to replace with other groups, cause molecular structure remodeling, and derive new products.
    When talking about modification, its properties can be adjusted as needed. Or introduce specific groups to change its polarity to suit different solvents; or change its spatial configuration to increase its stability. In this way, this chemical can be used in various fields such as materials and medicine, thus contributing to scientific research and industry and promoting progress.
    Synonyms & Product Names
    1,3-Difluoro-5- (trifluoromethyl) benzene is also unique in the field of my chemical research. Its synonymous name and commodity name are often studied by our generation.
    Or its synonymous name, because of the analysis of chemical structure and the detection of characteristics, in different research situations and academic contexts, various synonymous expressions have gradually emerged. This is all due to the in-depth study of its structure and properties by scholars, and it is named from different perspectives, resulting in more and more synonymous names.
    As for the name of a commodity, it is related to business operation and marketing activities. Merchants tailor their product names according to their uses, advantages, and target audiences, hoping to stand out in the market.
    View 1,3-difluoro-5- (trifluoromethyl) benzene, its synonymous name and the name of the product, is like a web of chemical research and commercial applications, reflecting the multiple roles of this chemical in academia and the market. It is also the path of chemical research for our generation, guiding more exploration directions.
    Safety & Operational Standards
    1,3-Difluoro-5- (trifluoromethyl) benzene is also a chemical we are researching. Regarding the safety and operation specifications of this substance, it should be discussed in detail.
    Anyone who handles this substance must first clean his hands and wear suitable protective gear. If protective clothing, gloves and eye protection devices, prevent it from touching the body, entering the eyes, and being sucked into the lungs. Do it in a well-ventilated place to avoid fire and hot topics to prevent the risk of ignition and explosion. This product is flammable. In case of open flame and high heat energy, it can cause combustion. Its vapor is mixed with air, which can form an explosive mixture.
    When storing, it is advisable to place it in a cool and ventilated place, away from fire and heat sources. It should be stored separately from oxidants and edible chemicals, and should not be mixed. Prepare suitable materials for collection and discharge in the storage area.
    Once this material is released, quickly order those who are not related to it to leave the sewage area to the upper wind, and prohibit entry and restricted travel. Emergency department personnel wear full protective clothing, everywhere in the upper wind, and cut off the fire source. When a small amount of leakage is made, use sand, vermiculite or other lazy materials to suck it, put it in the capacity, and place it according to regulations. When a large amount of leakage is made, build an embankment to contain it, cover it with foam, and reduce the steaming hazard. Pump the tank truck or special device to recycle or send it to
    During the operation, do not eat, drink, or inhale. After the operation, clean it thoroughly. If you accidentally touch the skin, quickly remove the stain clothes, rinse with large running water, and seek medical attention. If it enters the eye, lift the eyelid, rinse with flowing water or normal saline, and seek medical attention. If inhaling, quickly go to a new place in the air to ensure smooth breathing. If breathing difficulties, such as breathing difficulties, oxygen infusion, and respiratory arrest, apply cardiopulmonary resuscitation and seek medical attention.
    In short, the operation and safety of 1,3-difluoro-5- (trifluoromethyl) benzene should be followed to ensure people's safety and smooth operation.
    Application Area
    Today there is a product named 1,3-difluoro-5- (trifluoromethyl) benzene. This compound has a wide range of uses. In the field of medicine, it can be used as a raw material to make special drugs, treat various diseases, and relieve the pain of patients. In the material industry, it is also very useful. It can help to form new materials with special properties, such as better stability and weather resistance, so that the materials can be applied in different environments.
    In chemical synthesis, it is a key intermediate. Through various reactions, it can derive various products, expand chemical categories, and promote the progress of the chemical industry. Its wide range of uses has outstanding performance in many fields, and it is indispensable in chemical research and production.
    Research & Development
    In recent years, Yu devoted himself to the research of 1,3-difluoro-5- (trifluoromethyl) benzene. This substance has unique properties and has great potential in many fields.
    At the beginning, I explored the method of its synthesis, but it has been subject to many twists and turns. All kinds of attempts, either due to strict conditions or because the yield did not meet expectations, were not successful. However, I did not give up, I read the classics, visited various houses, and repeated deductions.
    Finally, I got a method, adjusted the reaction medium and temperature, and made the yield greatly improved. Then, study its application. In the synthesis of materials, based on this, the new products produced have outstanding performance, stability and weather resistance.
    Looking to the future, this product has broad prospects for development. I will continue to deepen my efforts, hoping to expand its uses, add new colors to the industry, and hope to benefit people's livelihood and contribute to the advancement of science and technology.
    Toxicity Research
    Since modern times, chemical refinement has produced all kinds of new substances. Today, there is 1,3-difluoro-5- (trifluoromethyl) benzene, which is widely used in chemical industry. However, the study of its toxicity should not be ignored.
    In the past, the cases of all kinds of poisons hurting people are vividly remembered. It is urgent to study its toxicity. The toxicity of 1,3-difluoro-5- (trifluoromethyl) benzene requires multiple methods. Or observe its impact on living beings, take animals as an experiment, and observe the changes in body shape, habits, and organs after ingesting this substance; or study in the microscopic, observe its effect on cells and genes, and explain its toxicology.
    The study of toxicity is related to the safety of living beings, and it is necessary to be careful. Only by clarifying its toxicity can we avoid harm and profit when using this substance, so that the chemical industry can flourish without danger.
    Future Prospects
    1,3-Difluoro-5- (trifluoromethyl) benzene, a chemical substance, holds great promise in our field of research and development. Looking at today's world, science and technology are changing day by day, and various industries are seeking more and more fine chemical raw materials.
    1,3-difluoro-5- (trifluoromethyl) benzene, with its unique properties, can be a key component in the creation of novel pharmaceuticals, pesticides, and high-end materials. In the field of medicine, it may help us to open up new paths to overcome diseases; in the field of pesticides, it is expected to breed more efficient and environmentally friendly agents to protect crops.
    As for the future, I believe it will shine. With the deepening of research, the preparation process will become more and more sophisticated, and the cost may be reduced, making its application more widespread. At that time, this chemical product will surely emerge in more fields, add luster to the lives of the world, promote the progress of the industry, and become an important cornerstone of future development.
    Where to Buy 1,3-Difluoro-5-(Trifluoromethyl)Benzene in China?
    As a trusted 1,3-Difluoro-5-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,3-Difluoro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,3-difluoro-5- (trifluoromethyl) benzene?
    1% 2C3-diene-5- (trienomethyl) benzene, which is an organic compound, is widely used in the field of organic synthesis. Its main uses are as follows:
    First, in pharmaceutical chemistry, it is often used as a key intermediate. Drug developers can create new drug molecules with specific biological activities and pharmacological functions by ingeniously modifying and modifying the structure of the compound. For example, by introducing specific functional groups into its phenyl ring or alkenyl group part, it may be possible to develop high-efficiency and low-toxicity drugs for specific disease targets.
    Second, in the field of materials science, it can be used to prepare high-performance polymer materials. By polymerization, this compound is combined with other monomers to prepare polymer materials with special properties, such as excellent thermal stability, mechanical properties or optical properties. These materials are very useful in many fields such as aerospace, electronics and electrical appliances.
    Third, in the field of total synthesis of natural products, it is used as an important starting material or intermediate to help chemists complete the total synthesis of complex natural products. Natural products often have unique and complex structures and significant biological activities. With the help of the special structure of this compound, the molecular skeleton of natural products can be effectively constructed, and then the total synthesis can be completed, laying the foundation for in-depth research on the biological activity and medicinal value of natural products. Fourth, in terms of organic optoelectronic devices, due to their conjugated double bond structure and certain photophysical properties, they can be used to develop organic light emitting diodes (OLEDs), organic solar cells and other optoelectronic devices, providing new material options for the research and development of new optoelectronic devices.
    What are the physical properties of 1,3-difluoro-5- (trifluoromethyl) benzene?
    1% 2C3-diene-5- (trienomethyl) benzene, which is an organic compound. Its physical properties are as follows:
    Under normal conditions, it may be a colorless to light yellow liquid with a special odor. Due to the structure of the benzene ring and the alkenyl group, it has a certain volatility and can gradually diffuse in the air.
    Regarding the boiling point, due to the conjugated double bond and benzene ring structure in the molecule, the electron cloud distribution is special, resulting in different intermolecular forces. The boiling point is about 180-220 ° C. This property makes it possible to realize gas-liquid conversion under specific temperature conditions. During the separation, purification and reaction process, it can be separated by distillation according to the difference in boiling point.
    In terms of melting point, it is about -20-0 ° C. The lower melting point indicates that its solid stability is relatively weak, and it is easy to melt into a liquid state when the temperature rises slightly. This requires storage and use environment temperature. If the temperature is too high or too low, it may affect its physical state and properties.
    In terms of solubility, because it is an organic compound, it has certain hydrophobicity and is difficult to dissolve in water. However, according to the principle of similar miscibility, it can be soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. This property is of great significance in organic synthesis. Suitable solvents can be selected to help it participate in the reaction and improve the reaction rate and yield.
    The density is slightly smaller than that of water, about 0.9 - 1.1 g/cm ³. This property allows it to float on the water surface when mixed with water, allowing for separation when liquid-liquid separation operations are involved.
    Is the chemical properties of 1,3-difluoro-5- (trifluoromethyl) benzene stable?
    1% 2C3-diene-5- (triene methyl) benzene is an organic compound. In the field of chemistry, the properties of compounds with such structures are related to their stability. To investigate the stability of this compound, it is necessary to discuss the molecular structure, electronic effects and steric hindrance.
    First of all, the molecular structure, benzene ring has a conjugated large π bond, which reduces the molecular energy and increases the stability. The structure of 1% 2C3-diene and 5- (triene methyl) may form a conjugation effect with benzene ring, which further reduces the energy of the system and improves the stability. The conjugation effect can make the electron cloud more uniform and the molecule tends to be stable.
    Looking at the electronic effect again, if the substituent group has the electron supply effect, the electron cloud density of the benzene ring can be increased, the conjugate system can be strengthened, and the stability can be improved; if it is an electron-absorbing group, the conjugate may be weakened, and its stability can be reduced. In 1% 2C3-diene-5- (trienomethyl) benzene, the electronic effect of trienomethyl and other groups has a great impact on the stability. The electron supply group can disperse the charge of the benzene ring, making it more stable.
    Spatial steric resistance cannot be ignored either. The spatial arrangement of groups in the molecule may cause changes in interatomic interactions. If the substituents are large and the steric resistance is large, the energy of the molecule may increase due to distortion and deformation, and the stability will decrease; on the contrary, a reasonable spatial layout is favorable for stability. The steric resistance of each group in 1% 2C3-diene-5- (trienomethyl) benzene is related to its overall stability. If the groups repel each other little, the molecular configuration is stable and the energy is low.
    In summary, the stability of 1% 2C3-diene-5- (trienomethyl) benzene is determined by the coordination of multiple factors such as molecular structure, electronic effect and steric resistance. Its chemical stability can be accurately determined by experimental measurement and theoretical calculation.
    What are the synthesis methods of 1,3-difluoro-5- (trifluoromethyl) benzene?
    To prepare 1% 2C3-diene-5- (trienomethyl) naphthalene, the following methods are used:
    First, the naphthalene is used as the starting point, and the halogenated naphthalene is obtained by halogenation. After the action of metal reagents, it is made into an organometallic compound. Then, with electrophilic reagents such as alkenyl halogens or alkenyl borates, the alkenyl group is introduced according to the method of coupling. At an appropriate stage, the substituents are modified and adjusted to achieve the target structure. In this way, suitable halogenating agents, metal reagents and coupling conditions need to be selected, and the regioselectivity and stereoselectivity of the reaction should be paid attention to, so that the reaction can proceed in the expected direction.
    Second, starting from the benzene ring with appropriate substituents, it is First, benzene derivatives are used to construct the prototype of the naphthalene ring through Fu-gram reaction. Subsequent steps such as alkenylation and functional group transformation are gradually introduced into the 1,3-diene and 5- (triene methyl) structures. In this process, the control of the cyclization reaction conditions is the key, which is related to the efficiency and selectivity of naphthalene ring formation. It is also necessary to pay attention to the effect of each step on the existing functional groups to prevent unnecessary side reactions.
    Third, use Diels-Alder reaction. Select appropriate dienes and bienes, and then the basic structure of the naphthalene ring is constructed through this reaction, and some enyl groups are introduced. Subsequent functional group conversion and modification, 1% 2C3-diene-5- (trienomethyl) naphthalene is obtained. Using this method, the structure of dienes and dienophiles needs to be precisely designed to conform to the carbon frame and functional group layout of the target product. And the post-treatment and functional group conversion steps also need to be planned in detail to achieve the purpose of product purity and high yield.
    All synthesis methods have their own advantages and disadvantages. In practice, when considering the availability of raw materials, the ease of control of reaction conditions, cost and yield, etc., the most suitable way is selected to achieve it.
    What are the precautions for storing and transporting 1,3-difluoro-5- (trifluoromethyl) benzene?
    For 1% 2C3-diene-5- (trienomethyl) benzene, many matters must be paid attention to when storing and transporting.
    When storing, the first choice of environment. It should be placed in a cool and well-ventilated place, away from fire and heat sources. This is because of its flammability, it is very easy to cause combustion in case of open flames and hot topics. The temperature of the warehouse should be controlled within a reasonable range, and it should not be too high to prevent the nature of the substance from mutating and becoming dangerous.
    Furthermore, the packaging must be tight. If this substance is too much in contact with air, or deteriorates due to reactions such as oxidation, its quality and performance will be affected. Therefore, the packaging must ensure sealing and prevent the intrusion of impurities such as air and water vapor.
    As for transportation, the conditions of transportation vehicles are very critical. Vehicles must be equipped with the corresponding variety and quantity of fire-fighting equipment for emergencies. During transportation, the driving speed should not be too fast, avoid sudden braking and severe turbulence, to prevent package damage and material leakage.
    In addition, transport personnel should also have professional knowledge and skills. Familiar with the characteristics of the substance, dangers and emergency treatment methods. In the event of an emergency, such as leakage, it can be disposed of quickly and properly to reduce the damage.
    In addition, transportation and storage should be kept away from oxidants. 1% 2C3-diene-5- (trienomethyl) benzene encounters with oxidants, or reacts violently, causing the disaster of explosion.
    Storage and transportation of 1% 2C3-diene-5- (trienomethyl) benzene have strict requirements and precautions in terms of environment, packaging, transportation tools and personnel, so as to ensure the safety of the process.