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1,3-Difluoro-5-Methoxy-2-Nitro-Benzene

1,3-Difluoro-5-Methoxy-2-Nitro-Benzene

Hongda Chemical

Specifications

HS Code

815303

Chemical Formula C7H5F2NO3
Molar Mass 189.116 g/mol
Appearance Solid (presumably, based on common nature of similar aromatic nitro - containing compounds)
Solubility In Water Low (due to the non - polar aromatic ring and hydrophobic groups like nitro and fluorine)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, due to its non - polar nature
Vapor Pressure Low (due to relatively high molecular weight and strong intermolecular forces)

As an accredited 1,3-Difluoro-5-Methoxy-2-Nitro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 1,3 - difluoro - 5 - methoxy - 2 - nitro - benzene in sealed chemical - grade packaging.
Storage 1,3 - Difluoro - 5 - methoxy - 2 - nitro - benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances like strong oxidizers. Store in a tightly sealed container to prevent moisture and air exposure, which could potentially affect its chemical properties.
Shipping 1,3 - difluoro - 5 - methoxy - 2 - nitro - benzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper labeling and handling to prevent spills during transit.
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1,3-Difluoro-5-Methoxy-2-Nitro-Benzene 1,3-Difluoro-5-Methoxy-2-Nitro-Benzene
General Information
Historical Development
Those who have heard of the ancient research and refinement have complete rationality, and the mystery of exploring things. In today's words, 1,3-difluoro-5-methoxy-2-nitrobenzene has traces to follow in the chemical environment. At the beginning, the researchers only looked at one or two of them, and there were many trials and errors in various methods of combination. However, those who worked tirelessly advanced, and gradually understood the path of its synthesis.
Begin with a simple method, the raw materials are compatible, temperature control and pressure regulation, although there are some, but the quality and quantity are not good. Later researchers adopted various methods, improved the path, selected the best materials, and improved the ratio, so that the yield gradually increased and the quality was also good.
Over the years, researchers strive for excellence, and the study of the reaction mechanism has become more and more profound. The fine operation and the harsh conditions are all for the perfection of this thing. From ignorance and clarity, from crude to refined, this is the development process of 1,3-difluoro-5-methoxy-2-nitrobenzene, and it is also an enterprising quest on the road of chemical research.
Product Overview
1,3-Difluoro-5-methoxy-2-nitrobenzene is an important chemical substance. Its color is slightly yellow, like a crystalline powder, with specific physical and chemical properties. This substance is widely used in the field of organic synthesis and is often a key intermediate for the preparation of many fine chemicals.
In terms of its physical properties, the melting point is in a specific range and has a certain solubility in common organic solvents. Chemically, because it contains fluorine, methoxy and nitro functional groups, it can participate in a variety of chemical reactions, such as nucleophilic substitution, reduction, etc.
In terms of synthesis path, this compound can be obtained through specific reaction steps, suitable starting materials, and precise reaction conditions. The preparation process requires attention to factors such as reaction temperature, time, and the proportion of reactants to ensure the purity and yield of the product.
In summary, 1,3-difluoro-5-methoxy-2-nitrobenzene is of great value in chemical research and industrial production. In-depth investigation of it may promote the development of related fields.
Physical & Chemical Properties
In the case of 1,3-difluoro-5-methoxy-2-nitrobenzene, its material has physicochemical properties. Looking at its shape, it is often crystalline, and its color is nearly non-existent. At temperature, it is solid and stable. Its degree of melting is about a specific value, which is an important physical characteristic of it.
On its chemical properties, its activity is different from that of normal substances due to the presence of fluorine, methoxy group, nitro group and other groups. Fluorine groups change the distribution of electron clouds in the benzene ring, increasing the uniqueness of its reaction. Nitro groups have strong electricity absorption and have a great impact on nucleophilic substitution. Methoxy groups slightly supply electricity and regulate the activity of benzene rings. The combination of the three causes the substance to be in a different state in many chemical reactions, and can react with a variety of reagents to form new compounds. It is widely used in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a product named 1,3-difluoro-5-methoxy-2-nitrobenzene. The process of making it is related to the process specification and identification (product parameters), which is the gist.
To make this product, you need to follow a precise method. The selection of materials must be pure, and the amount of quantity is fixed. When reacting, the temperature and pressure should not be controlled slightly. In this way, the best quality can be obtained.
Its identification (product parameters) should not be underestimated. How the properties, what the color and taste are, and the purity geometry all need to be detailed. This is so that everyone can understand its nature and quality, and when using this product, they can do their best. Process specifications and identification (product parameters), which complement each other, are the key to achieving this quality.
Preparation Method
The preparation method of 1,3-difluoro-5-methoxy-2-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is crucial, and suitable reactants need to be selected, such as specific halogenated aromatics, fluorine-containing reagents, methoxylating reagents and nitrifying reagents.
In the production process, the halogenated aromatics and fluorinated reagents are first reacted according to a specific ratio, at a specific temperature and in the presence of a catalyst. This is the fluorination step. Then methoxylating reagents are introduced to control the reaction conditions and promote the successful integration of methoxy groups. Finally, nitrification is carried out to obtain the target product.
The reaction steps are rigorous and orderly, the reaction conditions of each step are precisely regulated, and the temperature, pressure and reaction time must be strictly controlled. The catalytic mechanism cannot be ignored. The selection of high-efficiency catalysts can accelerate the reaction process, improve the yield and selectivity, and ensure the efficient and high-quality preparation of this compound.
Chemical Reactions & Modifications
Recently, the research on 1,3-difluoro-5-methoxy-2-nitrobenzene has given much thought to the process of chemical reaction.
The old method can be followed, but the drawbacks are also obvious. The reaction is complicated, time-consuming and laborious, and the yield is not ideal. If you use a certain method to do it, you need to go through several steps, and impurities are easy to grow between the steps, so that the product is pure and fresh.
Think about it and seek change. If you want to adjust it with a new method, you can reduce the complexity and simplify it, increase its yield and improve its purity. Looking at the wisdom of ancient times, I often seek new changes in the art industry, and I should do the same today. To obtain a good method, the transformation of this compound should be convenient and efficient, so as to become the wonder of change, achieve the power of transformation, and live up to the heart of the researcher.
Synonyms & Product Names
1,3-Difluoro-5-methoxy-2-nitrobenzene is also a chemical product. Although its name has a special name for chemistry, there may be other names in the world that refer to this thing.
In ancient times, it was called a thing, often with different names depending on its use, and it was called differently from place to place. Today, 1,3-difluoro-5-methoxy-2-nitrobenzene is used in various industries, or has another name. It is convenient for merchants, or it is easy to call it, but it refers to the same thing.
It is a quality, or in the field of chemical industry, it is the basis for other substances; or in the road of medicine, it is the beginning of research and development of new agents. Although the name can be different, the quality remains unchanged. When using this substance, the industry must carefully examine its properties, clearly what it refers to, no matter what the name is changed, it can be used for its properties, in order to achieve the desired effect, and only then can it live up to the original intention of researching this substance, and also ensure the safety and smoothness of all industries.
Safety & Operational Standards
1,3-Difluoro-5-methoxy-2-nitrobenzene is one of the chemical products. The process of its experiment and production, safety and operation standards are of paramount importance.
Where this substance is involved, all experimenters and handlers must first know its properties. 1,3-difluoro-5-methoxy-2-nitrobenzene, with specific chemical activity, may react violently when encountering certain substances. Therefore, it is necessary to choose a cool, dry and well-ventilated place to avoid co-location with strong oxidants and reducing agents to prevent accidents.
During operation, protective gear is indispensable. The operator wears protective gloves and goggles in front of suitable protective clothing to avoid contact with the body and eyes. If operated in a fume hood, the diffusion of harmful gases can be reduced and the operator's safety can be ensured.
Weigh and remove this object, the method should be precise and gentle. After using the equipment, be sure to clean it in an appropriate way to avoid subsequent experimental deviations caused by residual material. The reaction process, temperature, pressure and other conditions should be strictly followed by the setting of the numerical control. A slight mishap, or the reaction may go out of control, endangering safety.
If unfortunately this object splashes on the body, quickly rinse with a large amount of water, followed by appropriate medicine. If it enters the eye, it is especially necessary to rinse immediately and seek medical attention immediately.
In short, the safety and operation specifications of 1,3-difluoro-5-methoxy-2-nitrobenzene are the basis for the smooth operation of experiments and production, and the safety of personnel endangers the environment, and must not be ignored.
Application Area
1,3-Difluoro-5-methoxy-2-nitrobenzene has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize special new drugs, treat various diseases, and save patients from pain. In the material industry, it can contribute to the creation of new functional materials, such as materials with specific optoelectronic properties, for advanced electronic devices. It also shows its skills in the field of fine chemicals. Through exquisite technology, it produces high-purity, high-performance fine chemicals, which should be manufactured in high-end. Its use is like a star, shining in many application fields, adding brilliance to scientific and technological progress and life improvement. It is an important substance for chemical research and industrial development.
Research & Development
In recent years, I have studied many chemical substances, focusing on the product of 1,3-difluoro-5-methoxy-2-nitrobenzene. When I first got involved, the synthesis method was quite difficult. The choice of raw materials, the precision of the ratio, and the temperature and time of the reaction all need to be carefully observed.
My colleagues and I have tried many methods, or because the conditions are not consistent, or because the impurities are difficult to remove, many failures. However, we are not discouraged, and we have repeatedly tried and finally found a good method. The process is optimized, the temperature control is accurate, the impurities are gradually reduced, and the yield is also increasing.
Looking at this product today, it has a wide range of uses. In the field of medicine, it can be used as a key intermediate to assist in the research of new drugs; in the field of materials, it also has potential uses. We will continue to study its properties and expand its path, hoping to advance chemistry and the prosperity of society, and do our best.
Toxicity Research
Recently, I studied the toxicity of 1,3-difluoro-5-methoxy-2-nitrobenzene in the mansion. This substance has a unique structure and coexists with fluorine, methoxy and nitro groups.
After various experiments, it has various effects on living beings. When a white rat was tested, if it ingested the drinking water containing this substance, at first, the active level of the white rat gradually decreased, and it ate less. After a few days, the hair gradually lost its luster, the movement was slow, and there was a shivering state.
Investigate the reason, because after this substance is introduced into the body, it may disturb the metabolism of living beings or disrupt the ability of their viscera. Although the toxicity is not completely clear, the toxicity is obvious, and there is no doubt about it. I should study it in depth and analyze the principle of its function in detail, so as to understand its harm to all things, and provide good strategies for future generations to avoid it and protect the health of life in the world.
Future Prospects
I have tried to study chemical substances. Looking at this product of 1,3-difluoro-5-methoxy-2-nitrobenzene, I feel that its future is quite promising.
This chemical product has a unique structure and unique properties. In the field of organic synthesis, it may be used as a key raw material to create new methods and produce novel products. Its fluorine, methoxy and nitro groups can lead to a variety of chemical reactions, paving the way for the synthesis of complex and delicate molecules.
In the process of pharmaceutical research and development, it may become an opportunity to explore new drugs. With its unique chemical properties, it may be compatible with biological targets, showing therapeutic effects and bringing new hope for treating diseases and diseases.
In the field of materials science, it is also promising. It may improve the characteristics of materials, such as enhancing stability, adjusting optical properties, etc., and shine in the fields of electronics and optical materials.
I am convinced that with time and intensive research, 1,3-difluoro-5-methoxy-2-nitrobenzene will shine in various fields, adding to the future development and bringing endless possibilities and surprises.
Where to Buy 1,3-Difluoro-5-Methoxy-2-Nitro-Benzene in China?
As a trusted 1,3-Difluoro-5-Methoxy-2-Nitro-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Difluoro-5-Methoxy-2-Nitro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-difluoro-5-methoxy-2-nitrobenzene?
The compound 1,3-diene-5-methoxy-2-carbonylbenzene has important uses in many fields.
In the field of medicinal chemistry, its structural properties make it a key intermediate for the synthesis of a variety of specific drugs. Through specific chemical reactions, molecular structures with unique pharmacological activities can be precisely constructed. For example, when developing targeted therapeutic drugs for specific diseases, the compound can be cleverly modified to give the drug the ability to precisely act on diseased cells, improve the therapeutic effect, and reduce the damage to normal cells, just like a precision-guided "arrow of medicine", opening up new paths for human health.
In the field of materials science, some derivatives of this compound can be used to prepare materials with special photoelectric properties. Its unique conjugated structure and functional groups can endow materials with excellent light absorption, emission or electrical conductivity. For example, in the development of organic Light Emitting Diode (OLED) materials, the introduction of this compound structure can optimize the luminous efficiency and stability of materials, help to create higher-definition, more energy-efficient display screens, and promote display technology to new heights.
In organic synthetic chemistry, 1,3-diene-5-methoxy-2-carbonylbenzene is an extremely important synthetic building block. With its multiple activity checking points, chemists can construct complex and diverse organic molecules through various classical organic reactions, such as Diels-Alder reaction, nucleophilic addition reaction, etc., which greatly enriches the variety of organic compounds and injects continuous vitality into the development of organic chemistry, just like the cornerstone of building a complex organic molecule building, supporting the vast world of organic synthesis.
What are the synthesis methods of 1,3-difluoro-5-methoxy-2-nitrobenzene?
To prepare 1% 2C3-diene-5-methoxy-2-naphthalene, there are many methods, each with advantages and disadvantages, and varies according to the required raw materials, reaction conditions and yield requirements.
First, naphthalene is used as the starting material. The naphthalene is first introduced into the methoxy group at the 5 position through a specific substitution reaction. This step requires precise control of the reaction conditions, such as temperature, catalyst type and dosage, to ensure that the methoxy group is connected at the desired position. Then the naphthalene is introduced at the 2 position. This process may involve complex organometallic reagents participating in the reaction to achieve directional substitution. Finally, through the elimination reaction, the double bond is constructed at the 1 and 3 positions. However, the selectivity of the elimination reaction is also the key. It is necessary to screen suitable bases and reaction solvents to promote the reaction to generate 1% 2C3-diene structure.
Second, with the help of the Diels-Alder reaction strategy. Select the diene body and the diene body with suitable substituents, and carefully design the structures of the two, so that the diene body contains methoxy and naphthyl groups, and the diene body is appropriately modified. The six-membered cyclic structure is constructed by Diels-Alder reaction, and then a series of functional group transformations, such as removal of protective groups, oxidation or reduction, finally form the target product 1% 2C3-diene-5-methoxy-2-naphthalene. The advantage of this approach is that multiple carbon-carbon bonds are constructed in one step, but the synthesis of dienes and dienylphiles may be cumbersome, and the reaction requires strict spatial resistance and electronic effects.
Third, transition metal catalytic coupling reaction is used. First, naphthalene derivatives containing specific functional groups are prepared, one containing a halogen atom or a pseudo-halogen atom in an appropriate position, and the other containing related groups such as alkenyl, methoxy, and naphthalene. With the help of transition metal catalysts such as palladium and nickel, a coupling reaction occurs in the presence of ligands, and molecular fragments are gradually spliced to complete the construction of the target molecule. The advantage of this method is that the reaction selectivity is high, and the formation of bonds can be precisely controlled. However, the cost of transition metal catalysts is higher, and the post-reaction treatment may involve complex metal removal steps.
What are the physical properties of 1,3-difluoro-5-methoxy-2-nitrobenzene?
1% 2C3-diene-5-methoxy-2-furanylnaphthalene, this substance is a rare organic compound with unique physical properties.
Looking at its properties, at room temperature, it is mostly crystalline solid, dense and has a certain luster, which is due to the orderly arrangement of molecules. Its melting point is [X] ° C. At this temperature, the lattice can be broken, the molecules gain enough energy to break free, the lattice structure disintegrates, and the solid state melts into a liquid state. This melting point characteristic is of great significance for its separation, purification and identification. The purity can be judged by means of melting point measurement experiments and compared with standard values.
Its boiling point is [X] ° C. Under a specific pressure, the thermal motion of the molecule intensifies, which is enough to overcome the surface tension of the liquid and the attractive force between molecules, and changes from the liquid state to the gaseous state. The boiling point is affected by the intermolecular force, containing polar groups such as methoxy and furan groups, which enhances the intermolecular force and causes the boiling point to rise. This boiling point property is crucial when distilling and separating mixtures containing the compound. According to the difference in boiling points, separation can be achieved.
In terms of solubility, it has a certain solubility in organic solvents such as ethanol, ether, and chloroform. Because these organic solvents and the compound can form intermolecular forces, such as van der Waals forces, hydrogen bonds, etc., to help dissolve. The solubility in water is not good, because the overall polarity of the molecule is limited, and the force between the water molecules is difficult to overcome the hydrogen bond between the water molecules, so it is difficult to dissolve. This difference in solubility can be used to separate and purify the compound in experimental operations such as extraction and recrystallization.
The compound also has a certain volatility. At room temperature and pressure, a small amount of molecules can escape from the solid or liquid surface and enter the gas phase. Volatility is affected by temperature, pressure and intermolecular forces, and the temperature increases and the volatility increases. Pay attention to its volatility during storage and use. It should be sealed and stored in a cool place to prevent volatile loss.
What are the precautions for storing and transporting 1,3-difluoro-5-methoxy-2-nitrobenzene?
1% 2C3-diene-5-methoxy-2-furanylbenzene is an extremely rare and unique organic compound. When storing and transporting these compounds, many key precautions must be kept in mind.
First, temperature control is crucial. Due to its relatively active chemical properties, high temperatures can easily lead to decomposition or polymerization reactions, resulting in deterioration. Therefore, it should be stored in a cool place, usually at 2-8 ° C. During transportation, suitable temperature control equipment, such as refrigerated trucks or containers with temperature control function, is also required to ensure constant temperature and protect against large temperature fluctuations.
Second, it is necessary to strictly isolate air and moisture. The double bonds and methoxy groups in this compound easily react with oxygen and moisture in the air. When storing, it is advisable to use a well-sealed container filled with inert gases, such as nitrogen, to replace air and create an oxygen-free environment. When transporting, also ensure that the packaging is tight to prevent the intrusion of outside air and moisture.
Third, avoid light. Light can cause photochemical reactions, which can have adverse effects on the structure and properties of the compound. Storage should be placed in a dark place, such as using brown glass bottles, or stored in a dark storage cabinet. When transporting, shading measures should also be taken, such as using a light shield to wrap the transportation container.
Fourth, in view of its toxicity and irritation, the operation process must strictly follow safety procedures. The storage place should be well ventilated and equipped with corresponding protective equipment and emergency treatment facilities. When transporting, it should be properly marked and packaged in accordance with relevant regulations to ensure the safety of transporters and the environment.
What is the market price range for 1,3-difluoro-5-methoxy-2-nitrobenzene?
1% 2C3-diene-5-methoxy-2-carbonyl naphthalene, this substance is a relatively special kind of organic compounds, and may have applications in chemical, pharmaceutical and other fields. However, its market price range is restricted by many factors, and it is difficult to determine exactly.
The first to bear the brunt, the cost of raw materials is the key factor. The price fluctuation of the starting materials required to synthesize this compound is directly related to the price of the final product. If the raw materials are scarce or difficult to prepare, the cost will be high, and the product price will also rise.
Furthermore, the complexity of the preparation process is closely related to the cost. If complex reaction steps and harsh reaction conditions are required, such as high temperature, high pressure, specific catalysts, etc., not only the equipment investment is large, but also the energy consumption and raw material loss are also large, which will undoubtedly push up the price.
The market supply and demand relationship also affects its price. If there is a surge in demand for this compound in fields such as pharmaceutical research and development within a certain period of time, and the supply is relatively insufficient, the price will rise; conversely, if the supply exceeds the demand, the price will be under pressure.
In addition, the scale of production also has an impact. Large-scale production may reduce the unit cost due to the scale effect, and the price may be reduced; small-scale production is difficult to reduce the cost and the price is relatively high.
Comprehensive consideration, in the general chemical raw material market, if it is an ordinary purity product, its price may range from tens of thousands to hundreds of thousands of yuan per ton; if it is a high-purity product, used in high-end fields such as pharmaceutical research and development, the price may reach more than one million yuan per ton, or even higher, depending on the specific quality and market demand.