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1,3-Difluoro-5-Isothiocyanatobenzene

1,3-Difluoro-5-Isothiocyanatobenzene

Hongda Chemical

Specifications

HS Code

355041

Chemical Formula C7H3F2NS
Molecular Weight 171.17
Appearance Typically a solid
Odor Pungent due to isothiocyanate group
Melting Point Data may vary, needs experimental determination
Boiling Point Data may vary, needs experimental determination
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Solubility In Water Insoluble in water
Density Data may vary, needs experimental determination
Reactivity Reactive towards nucleophiles due to isothiocyanate group

As an accredited 1,3-Difluoro-5-Isothiocyanatobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - difluoro - 5 - isothiocyanatobenzene packaged in a sealed glass bottle.
Storage 1,3 - difluoro - 5 - isothiocyanatobenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat and ignition. It must be stored in a tightly - sealed container to prevent leakage, as it is likely reactive and may pose risks. Keep it separate from incompatible substances such as oxidizing agents, acids, and bases to avoid potentially dangerous reactions.
Shipping 1,3 - difluoro - 5 - isothiocyanatobenzene is a chemical. Shipping should follow strict regulations due to its nature. It must be properly packaged to prevent leakage, and shipped with correct hazard labels via approved carriers.
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1,3-Difluoro-5-Isothiocyanatobenzene 1,3-Difluoro-5-Isothiocyanatobenzene
General Information
Historical Development
1,3-Difluorophenyl-5-isothiocyanate is also a genus of chemical products. Its origin originated from the study of scholars in the past. At that time, various sages worked hard to explore the field of chemistry, hoping to open up new frontiers. At the beginning, the understanding of this thing was still shallow, and only a few characteristics were observed.
And later, with the passage of time, the research deepened. With unremitting perseverance, the sages repeatedly operated in the laboratory to analyze its structure and explore its reaction rules. Gradually understand its ability in various chemical reactions, and its use is gradually widening. Either enter the road of organic synthesis and contribute to the production of new compounds; or emerge in the field of material science and help the creation of new materials. This phenyl 1,3-difluoro-5-isothiocyanate, through the work of many masters, has finally become an indispensable existence in the field of chemistry, shining brightly in the long river of scientific development.
Product Overview
There is a compound called 1,3-difluoro-5-isothiocyanate. It is an organic compound with a special structure. Looking at its molecule, above the benzene ring, the fluorine atom is cleverly connected to the isothiocyanate root.
This compound is quite valuable in the field of organic synthesis. The introduction of fluorine atoms gives the compound unique physical and chemical properties. It can be used as a key intermediate to create a variety of new organic materials and drugs.
The existence of isothiocyanate base gives it active reactivity. It can react with many nucleophiles to derive products with rich structures. In the field of fine chemicals, this 1,3-difluoro-5-isothiocyanate phenyl ester is an important substance that cannot be ignored, and it has contributed greatly to the progress of organic synthetic chemistry.
Physical & Chemical Properties
1,3-Difluoro-5-isothiocyanate is also an organic compound. Its physical and chemical properties are worth studying. Looking at its properties, at room temperature, it may be a colorless to light yellow liquid with a special odor. Its boiling point, melting point and other physical constants are the keys to characterizing its properties. The boiling point is related to its gasification temperature. Under a specific pressure environment, it has its inherent value, which is closely related to the intermolecular force. The melting point is also the same, reflecting the transition temperature between its solid and liquid states.
As for chemical properties, isothiocyanate groups are very active and can react with many nucleophiles. If it meets with alcohols, it can form carbamate compounds; when it interacts with amines, it can also generate corresponding thiourea derivatives. These reactions, or in the field of organic synthesis, have great potential for the preparation of various organic intermediates, and then provide important raw materials for the creation of fine chemicals such as medicine and pesticides.
Technical Specifications & Labeling
Today there is a product called phenyl 1,3-difluoro-5-isothiocyanate. It is very important to explore the process specifications and identification (product parameters).
The process specifications of this product need to clarify the method of its synthesis. From the selection of raw materials, it must be carefully selected and compatible according to specific proportions. The reaction conditions are also critical, such as temperature, pressure, and reaction time, all of which must be precisely controlled. The instruments used in the process should also be in line with the standards to ensure stable reaction.
Besides the identification (product parameters), the properties of this product should be detailed, and the color, taste, and state should be clear. Its purity geometry and impurity content are several, which are related to the quality. In addition, there are physical constants such as melting point and boiling point, which cannot be missed. In this way, the product can be based on the process specifications and identification (product parameters) to achieve a good state.
Preparation Method
To prepare 1,3-difluorobenzene-5-isothiocyanate, the method is as follows:
Raw materials and production process: Pure fluorobenzene derivatives are selected as the base material, supplemented by isothiocyanated reagents. The ratio of the two needs to be accurate, and the dosage should be determined according to its chemical properties and reaction rules.
Reaction steps: First place the reactor in a suitable temperature environment, and control it with a precision temperature-controlled device. Add fluorobenzene derivatives into the kettle, followed by isothiocyanate esterification reagent, slowly stir it, and promote it to be fully mixed. During the reaction, closely monitor the changes in temperature and pressure, and adjust it in a timely manner to ensure that the reaction goes forward.
Catalytic mechanism: The addition of a high-efficiency catalyst can reduce the energy barrier of the reaction and speed up its progress. The catalyst activity is excellent and has good compatibility with the reaction system. Through these methods, it is expected to obtain high-purity phenyl 1,3-difluoro-5-isothiocyanate.
Chemical Reactions & Modifications
Taste the technology of chemical industry, it is very delicate, and the transformation of matter is wonderful. Today there is a thing named 1,3-difluoro-5-isothiocyanate phenyl ester, which is very important in chemical research.
Its chemical reaction is related to many changes. The method of the past may not be good, the reaction efficiency is not high, and the product is impure. Therefore, scholars have worked hard to change it.
People of today study its mechanism and explore its laws. Optimize the conditions of the reaction, adjust the temperature, control the pressure, and choose the appropriate solvent and catalyst. In this way, the reaction efficiency is greatly increased, and the purity of the product is also good. This is the evolution of chemistry, in response to the needs of the times, seeking change and innovation, in order to achieve the state of refinement, for scientific research and practical, all add help, so that this substance can play a greater role.
Synonyms & Product Names
1,3-Difluoro-5-phenyl isothiocyanate, which has attracted much attention in today's chemical research. According to Guanfu's ancient books, although there is no direct name for it, it is based on the concept of chemistry. Its similar substances may be found in the past.
In the ancient chemical search, all kinds of substances are called differently. Although there is no exact name of "1,3-difluoro-5-isothiocyanate", similar fluorine-containing and thiocyanate-containing compounds may have been noticed by the Fang family.
Although there were no accurate analytical methods at that time, the ancients used simple methods to observe the properties of substances and study the principles of change. If you look back in today's perspective, or have the characteristics of this compound, it will occasionally be revealed in the accounts of the ancients.
1,3-difluoro-5-phenyl isothiocyanate is widely used in the field of current chemistry, and is either a key material in organic synthesis or plays an important role in the development of new materials. Although it was not known in detail in the past, the development of chemistry has changed from simple to complex, from obscure to bright. The appearance of this substance is also one of the evidence of the evolution of chemistry.
Safety & Operational Standards
Safety and Operation Specifications of 1,3-Difluoro-5-phenyl isothiocyanate
If 1,3-difluoro-5-phenyl isothiocyanate is one of the chemical substances. Its special nature is related to safety and operation standards, and it should not be careless.
On the safe side, this substance is dangerous. Its odor is pungent and enters the respiratory tract, which can cause discomfort or even damage the respiratory organs. Therefore, when in contact, it is necessary to use protective equipment, such as masks, to filter its gas and protect people's breathing. And it may be irritating to the skin and eyes. If it touches the skin accidentally, rinse it with a lot of water quickly to remove its residue to avoid future problems. If it enters the eye, it needs to be buffered with water immediately, and medical treatment should not be ignored.
As for the operating specifications, first of all, the workplace must be well ventilated to circulate the air, reduce its concentration in the air, and reduce the risk of danger. When taking it, use special equipment, measure it accurately, and do not do it at will. During the operation, strictly abide by the operating procedures, and do not slack off. After the experiment is completed, properly clean the equipment, and dispose of the remaining materials according to regulations. Do not discard it indiscriminately, so as not to pollute the environment and cause safety disasters.
All of these are essential for the safety and operation of 1,3-difluoro-5-phenyl isothiocyanate. Practitioners should adhere to regulations to ensure their own safety, protect the safety of the environment, and promote the smooth development of chemical research and production.
Application Area
1,3-Difluoro-5-phenyl isothiocyanate, this chemical substance has a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs and find new ways to heal diseases. In material science, it can be integrated into the material structure through special reactions to improve the material properties, such as enhancing its stability and functionality. Although there is no precision instrument in the chemical research of Guafu Gu, the sages also used wisdom and diligence to explore the nature of matter and find the method of chemical combination. Today's 1,3-difluoro-5-isothiocyanate phenyl ester, inheriting the legacy of ancient research, brings its brilliance to many fields, helps the progress of science and technology, and seeks for the well-being of mankind. We should continue to study the unique knowledge of the Holy Land and unremitting research, so that this chemical thing can play a greater role and benefit the world.
Research & Development
In recent years, Yu dedicated himself to the research of phenyl 1,3-difluoro-5-isothiocyanate. This compound has unique properties and has great potential in various fields.
At the beginning, the method of its synthesis was explored. After repeated tests, it was obtained by a certain method, but the yield was not ideal. Then he devoted himself to research, improved the process, optimized the conditions, and the yield gradually increased.
Then, study its properties. Observe its physical properties, such as melting point, solubility, etc.; analyze its chemical activity, and its performance in different reactions.
And observe its application prospects. In the field of medicine, it is expected to lay the foundation for the research and development of new drugs; in the field of materials, it may be used as a raw material for new materials.
Yu Shenxin believes that with time and continuous exploration, phenyl 1,3-difluoro-5-isothiocyanate will surely shine in the path of research and development, bringing new opportunities to the industry.
Toxicity Research
Since modern times, chemical refinement, all kinds of compounds are changing with each passing day. Today there are 1,3 - Difluoro - 5 - Isothiocyanatobenzene this substance, and the investigation of its toxicity is quite important.
The investigation of the toxicity of this substance is related to the safety of life and the interests of the world. When studying the toxicity of this substance, it is necessary to be cautious and thorough. First examine its chemical structure, because it contains fluorine and isothiocyanate, or has special reactivity, and it is toxic.
Then look at its behavior in different media, in water, or dissociation or reaction, and what kind of products are produced, which is also related to the toxic effect. And test the animal, observe its physiological characteristics, organ changes, and record the symptoms in detail to reveal the toxicity, such as whether there is organ damage or behavioral abnormalities.
Only through this kind of investigation can we obtain the true meaning of the toxicity of this compound, which can provide evidence for future application, protection, and protection, so as to protect the world from its harm, so that this compound can play its function in the right way and avoid its harm.
Future Prospects
I have tried to study chemical substances, and now looking at 1,3-difluoro-5-phenyl isothiocyanate, I feel that its future development is quite promising. This compound may be a key raw material in the field of organic synthesis. Its unique structure, containing fluorine and isothiocyanate groups, makes it have special chemical activity.
In materials science, or due to the characteristics of fluorine, it can help to develop high-performance polymeric materials to increase their stability and functionality. In pharmaceutical research and development, isothiocyanate may be able to specifically combine with biological macromolecules, opening up new avenues for the creation of new drugs.
Although the current research may be limited, with time and in-depth investigation, we will be able to shine in the fields of chemical engineering, medicine, etc., and contribute to the future scientific and technological progress. It will become a treasure that our generation of researchers hope for and develop endless potential.
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Frequently Asked Questions

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What is the main use of phenyl 1,3-difluoro-5-isothiocyanate?
Menthyl 1,3-diene-5-isovalerate is an important organic compound with critical uses in a wide range of fields.
In the field of medicine, it may exhibit significant biological activity. The structure of menthyl glyceride often confers molecular-specific pharmacological properties, such as anti-inflammatory and antibacterial effects. This compound can assist in the treatment of diseases by interacting with specific targets in the body, or by modulating physiological processes. For example, its anti-inflammatory activity may relieve inflammation-related symptoms, providing ideas for the development of new anti-inflammatory drugs.
In the fragrance industry, menthyl glyceride may have a fresh and pleasant aroma. It can be used as a fragrance additive to prepare various flavors, add unique fragrance to perfumes, cosmetics, detergents and other products, enhance the olfactory experience of products, and satisfy consumers' pursuit of aroma.
In the field of organic synthesis, as an important intermediate, it has a unique structure and reactivity. Chemists can construct more complex organic molecular structures by performing specific chemical reactions on it. This provides an effective way for the synthesis of novel organic compounds, promotes the development of organic synthesis chemistry, and helps to develop new functional materials, drug lead compounds, etc.
1,3-diene-5-isovalenoic acid menthyl ester plays a significant role in the fields of medicine, fragrance, organic synthesis, etc., and is of great significance to the development of related industries.
What are the physical properties of phenyl 1,3-difluoro-5-isothiocyanate?
1% 2C3-diene-5-benzyl isopentenate is an organic compound with unique physical properties. Looking at its appearance, at room temperature and pressure, it is mostly a colorless to light yellow oily liquid, clear and transparent, under the light, or shimmering, like the twinkling dew on the lotus leaf in the morning.
When it comes to smell, this compound exudes a fragrant fragrance. Its fragrance is delicate and unique, like the fragrance of flowers mixed in a spring garden. It contains both a fresh and elegant taste and a hint of sweetness, just like the rich fragrance of many flowers intertwined, gentle and haunting, which is pleasing to the heart.
On the density, 1% 2C3-diene-5-benzyl isopentenoate is lighter than water. When it is placed in the same container as water, it can be seen that it floats lightly on the water surface, like a light feather floating on a blue wave.
In terms of solubility, it is a good friend of organic solvents. It can be miscible with common organic solvents, such as ethanol, ether, acetone, etc., just like a fish entering water, it is free. In these solvents, it can be quickly dispersed and fused. However, it is difficult to be compatible with water, and the two meet, like oil and water, they are distinct and independent.
Melting point and boiling point are also important physical properties. Its melting point is relatively low, and it is liquid at room temperature, like smart water, without a fixed shape, which changes with the shape of the container. The boiling point is higher, and it needs to be given a considerable amount of heat to make it change from liquid to gaseous. This process is like phoenix nirvana, which needs to be tested by high temperature. When heated to the boiling point, it will slowly rise like a curl of blue smoke, turning into a gaseous state and drifting into the air.
Is the chemical properties of phenyl 1,3-difluoro-5-isothiocyanate stable?
1% 2C3-diene-5-isothiocyanate phenyl ester, this is an organic compound. As for whether its chemical properties are stable, let me tell you one by one.
From the structural point of view, the compound contains carbon-carbon double bonds and isothiocyanate groups. The carbon-carbon double bond has high reactivity. Because of the exposure of π electron cloud, it is easily attacked by electrophilic reagents and triggers an addition reaction. For example, when it encounters electrophilic reagents such as halogens and hydrogen halides, the double bond is easy to react with and cause structural changes, indicating that the existence of double bonds affects the stability of the compound.
And isothiocyanate groups are not "safe". The carbon-nitrogen double bond in this group is connected to the sulfur atom. Due to the difference in electronegativity between nitrogen and sulfur, the carbon-nitrogen double bond electron cloud is unevenly distributed, and carbon is positively charged, making it vulnerable to nucleophilic reagents. Common nucleophilic reagents such as alcohols and amines are prone to nucleophilic substitution reactions once they are contacted, thereby changing the structure of the compound.
Overall, 1% 2C3-diene-5-isothiocyanate phenyl ester is chemically unstable due to the high reactivity of the carbon-carbon double bond and the isothiocyanate group, and it is easy to react with various reagents under suitable conditions, resulting in its own structure changes.
What is the production method of phenyl 1,3-difluoro-5-isothiocyanate?
The preparation method of 1% 2C3-diene-5-isopentenoic acid menthyl ester is related to the technology of chemical creation. What is the method, let me tell you in detail.
The husband prepares this product, often by chemical synthesis. In the past, many sages went through several steps and performed it skillfully. First take a suitable raw material, which may have an active functional group, which can start the end of the reaction. For example, choose a compound with an alkenyl group and a derivative isopentenoic acid ester group.
The first step often involves the pretreatment of the raw material. Or make it purified to remove the disturbance of impurities and make the reaction smooth. Then, according to the principle of organic synthesis, under suitable reaction conditions, the raw materials are interacted. This condition is related to temperature, pressure, catalyst, etc.
Temperature is crucial. If it is too high, the reaction will be too fast, which is prone to by-products; if it is too low, the reaction will be slow and time-consuming. Usually, it is appropriate to be moderately warm, or between tens of degrees Celsius, depending on the specific raw materials and reaction mechanism.
The pressure should not be ignored. Moderate pressure can make the reactants come into close contact and promote the reaction. However, if the pressure is too high, special equipment is required, and the cost will increase sharply. Therefore, the state of normal pressure or slightly increased pressure is often taken.
And the catalyst is a powerful artifact for the reaction. It can reduce the activation energy of the reaction and accelerate the reaction process. Choose a suitable catalyst, such as metal salts or organic bases, etc., to make the reaction efficient and specific.
After the above reaction, the crude product is obtained. After that, it still needs to be refined. Or use distillation to separate and purify according to the boiling point of each substance; or use extraction to extract the target product by means of solvent properties. In this way, after multiple processes, 1% 2C3-diene-5-isopentenoic acid menthyl ester is finally obtained.
This is a rough preparation method, and the details need to be fine-tuned according to the actual situation to achieve perfection and obtain a pure and suitable product.
What are the precautions for the storage and transportation of phenyl 1,3-difluoro-5-isothiocyanate?
1% 2C3-diene-5-isopentenoic acid geranyl ester. During storage and transportation, many matters need to be paid attention to.
First, temperature is very important. This compound is quite sensitive to temperature, and high temperature can easily cause it to decompose or deteriorate. Therefore, when storing, it should be placed in a cool place with a temperature of 2-8 ° C. If the temperature is too high, its molecular structure will be easily damaged, which will affect its quality and efficacy. During transportation, it is also necessary to ensure cold chain conditions to prevent excessive temperature fluctuations.
Second, the influence of light should not be underestimated. Light can trigger photochemical reactions, resulting in the degradation of the substance. When storing, it should be stored in a container protected from light, such as a brown glass bottle, to reduce the influence of light. During transportation, direct sunlight should also be avoided, and light-shielding packaging materials can be used.
Third, humidity is also a key factor. High humidity environment can easily make the substance absorb moisture, or cause reactions such as hydrolysis. Storage should be kept dry, and humidity should be controlled at 40% - 60%. During transportation, moisture-proof measures should be taken, such as adding desiccant to the package.
Fourth, the packaging must be tight. Choose suitable packaging materials to ensure sealing, prevent air, moisture and other intrusion, and consider its chemical stability and do not react with the compound. During storage and transportation, it is necessary to regularly check whether the packaging is in good condition. If it is damaged, it is necessary to replace the packaging in time to prevent the material from deteriorating.
Fifth, avoid contact with oxidants, acids, bases and other substances. Such substances are chemically active, and contact with them can easily trigger chemical reactions, resulting in the deterioration of 1% 2C3-diene-5-isovalerate geranyl ester. When storing and transporting, it should be stored and transported separately from the above substances.