Hongda Chemical
Products
Home  /  Products  / 

1,3-Difluoro-4-Nitrobenzene

1,3-Difluoro-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

913060

Chemical Formula C6H3F2NO2
Molar Mass 159.09 g/mol
Appearance Yellow solid
Melting Point 44 - 46 °C
Boiling Point 210 - 212 °C
Density 1.478 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 92.2 °C
Vapor Pressure Low at room temperature

As an accredited 1,3-Difluoro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,3 - Difluoro - 4 - nitrobenzene packaged in 500 - gram bottles for chemical use.
Storage 1,3 - Difluoro - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential reactions. Follow local safety regulations for chemical storage.
Shipping 1,3 - Difluoro - 4 - nitrobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, secure packaging to prevent leakage during transit.
Free Quote

Competitive 1,3-Difluoro-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1,3-Difluoro-4-Nitrobenzene 1,3-Difluoro-4-Nitrobenzene
General Information
Historical Development
1,3-Difluoro-4-nitrobenzene is a particularly important class of chemical products. Its origins can be traced back to the past, when chemical sages worked tirelessly and hoped to gain something.
At the beginning, everyone worked hard in the laboratory to explore the synthesis method. After countless attempts, they found a feasible way. Start with ordinary materials, according to exquisite formulas, and specific processes, to obtain the prototype of this product.
The years have passed, and the synthesis method has become more and more perfect. The sages have repeatedly considered the reaction conditions, the proportion of raw materials, etc., and strived for excellence. Each improvement makes the product more pure and better in yield.
Today, 1,3-difluoro-4-nitrobenzene shines in many fields, which is the fruit of past research and the cornerstone of future chemical development.
Product Overview
1,3-Difluoro-4-nitrobenzene is a key raw material for organic synthesis. Its properties are different, it is a light yellow to light brown crystalline solid, has a special smell, and is relatively stable in air.
The preparation of this compound is often obtained by specific fluorination and nitrification reactions. Through precise control of reaction conditions, such as temperature, reagent ratio, etc., ideal yield and purity can be obtained.
It has a wide range of uses. In the field of medicine, it is often an important intermediate for the creation of new drugs, which helps to develop special agents to fight various diseases. In the field of materials science, it can also contribute to the synthesis of special performance materials and improve the physical and chemical properties of materials.
When preparing and using 1,3-difluoro-4-nitrobenzene, safety procedures must be followed. Due to its certain toxicity and irritation, it is necessary to operate in a well-ventilated place and strictly implement protective measures to avoid endangering human health and the environment.
Physical & Chemical Properties
1,3-Difluoro-4-nitrobenzene is also a chemical substance. Its properties are both physical and chemical.

























> The existence of fluorine atoms makes it unique, and the nitro group is also diverse and reactive. For example, some nuclear and biochemical reactions can be made, and the nitro group can be replaced by the original, or other compounds, etc., which shows the enrichment of the industry. In the field of chemical synthesis, there is a possibility of multiple uses.
Technical Specifications & Labeling
Technical specifications and labels of 1,3-difluoro-4-nitrobenzene (commodity parameters)
For 1,3-difluoro-4-nitrobenzene, the technical specifications are the most critical. The properties of this product are colorless to light yellow liquid, with a specific boiling point, about [specific value] ℃, and accurate control of temperature is the key to preparation.
As for the logo, first and foremost, on the package, the name "1,3-difluoro-4-nitrobenzene" should be marked in a prominent font to prevent confusion. Second, its dangerous characteristics should be clearly stated, because it has certain toxicity and corrosiveness, and users should be warned to operate with caution. Among the product parameters, the purity must be above [X]%, and the impurity content must be strictly controlled. In this way, it can ensure that this chemical can be used safely and efficiently in industrial production, scientific research experiments and other fields, and live up to expectations.
Preparation Method
The preparation method of 1,3-difluoro-4-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical, and it is advisable to start with specific compounds containing fluorine and nitro groups. The production process requires precise control of the reaction conditions.
At the beginning of the reaction step, the selected raw materials are mixed in a specific ratio and introduced into the reactor. Heat up to a suitable temperature, usually around [X] ° C, at which the reaction activity is better. At the same time, an appropriate amount of catalyst is added to accelerate the reaction. This catalyst may be a metal salt, with its special electronic structure, reducing the activation energy of the reaction.
During the reaction process, closely monitor the degree of reaction, and use chromatographic analysis and other means to ensure that the reaction progresses in the expected direction. After the reaction is complete, a series of separation and purification steps, such as extraction, distillation, etc., can obtain a pure 1,3-difluoro-4-nitrobenzene product. In this way, the effective preparation of this compound can be obtained.
Chemical Reactions & Modifications
The way of chemical industry is related to the change of all things. Today, there is 1,3-difluoro-4-nitrobenzene, and its chemical reaction and modification are worth exploring.
The chemical reaction is the basis for material change. 1,3-difluoro-4-nitrobenzene has a unique structure, and the position of fluorine and nitro groups makes the reactivity very different. Or in the way of nucleophilic substitution, new groups can be introduced to change its properties.
As for modification, it is aimed at better properties. Chemical modification can be used to adjust its physical and chemical properties, such as degree of melting and boiling, and ability to dissolve, making it widely used in various fields. The method of modification, or adding groups, or variable bonding, to obtain new substances in order to meet the needs of industry and scientific research.
Looking at this substance, the potential for chemical reaction and modification is profound, and we need to study it in depth to understand its rationality and make good use of it, so as to contribute to the chemical industry.
Synonyms & Product Names
1,3-Difluoro-4-nitrobenzene is also a chemical product. Although its name is the same, synonymous words and commodity names also have their own names. In Fang's research, this thing may have other names, due to differences in uses and production methods, the title has also changed.
Although ancient chemistry is not as detailed as it is today, there are also lessons to be learned from the study of physical properties. Today's 1,3-difluoro-4-nitrobenzene, or in the records of the past, is expressed in different words. Although times have changed, the signs of physical properties should be found.
When looking at this product, the synonyms are related to its structure and nature, and the name of the product is related to production, sales and application. Both are essential to identify this product, and are meaningful to the research of scholars and the business. Studying its synonyms and the name of the product is like exploring the secret, which shows that this product is in the forest of chemistry, and it is also used for future use, research, and paving the way.
Safety & Operational Standards
Safety and Handling Specifications for 1,3-Difluoro-4-nitrobenzene
1,3-Difluoro-4-nitrobenzene is a compound commonly used in chemical research. In the experimental and production process, its safety and handling standards are of paramount importance.
This compound has certain toxicity and irritation. Contact with the skin, or cause redness, swelling, itching; when it enters the eyes, it can hurt the eyes, cause severe pain, and cause blurred vision. If inhaled, it also irritates the respiratory tract, or causes cough, asthma, etc. Therefore, during operation, protective measures are indispensable.
When the operator is wearing protective clothing, choose the one with good material and good airtightness to prevent it from contacting the skin. And wear protective gloves, choose the one that is resistant to chemical corrosion, and prevent penetration. Eye protection, goggles are necessary to ensure all-round protection. Masks are also indispensable. Choose the one with good filtration effect to prevent it from inhaling.
The operating environment should be well ventilated, and ventilation equipment should be installed to expel volatile gas in time. If it is operated in a fume hood, it is safer. Keep the operating table clean, clean up sundries and other chemicals, and prevent cross-contamination and reaction.
Use 1,3-difluoro-4-nitrobenzene, and the action should be stable and accurate. Use suitable utensils and use according to the amount. Do not cause too much waste and danger. Weigh in a stable place and use precise instruments. When transferring, be careful to prevent spills. When spills, clean up quickly. Small spills, adsorbed with adsorbents, such as sand, activated carbon, collected in special containers; large spills, evacuate people, block the scene, and professionally clean up.
Storage is also exquisite. Store in a cool, dry and ventilated place, away from fire and heat sources. Store separately from oxidizing agents, reducing agents, etc., to prevent reactions. Store in a closed container, clearly labeled, marked with names, dangerous characteristics, etc.
Operate 1,3-difluoro-4-nitrobenzene, strictly abide by safety and operation specifications, and ensure personnel safety, experimentation, and smooth production.
Application Area
Today there is a thing called 1,3-difluoro-4-nitrobenzene. Its application is quite wide. In the field of medicine, it can be used as a raw material to help doctors make special drugs, treat various diseases and relieve the suffering of patients. In the field of agrochemical, it can also be the foundation for creating agricultural agents, protecting crops from diseases and pests, and blessing the harvest. In the research and development of materials, it can be turned into the element for constructing special materials, so that the materials have specific properties and can be used for all kinds of ingenious purposes. Looking at this 1,3-difluoro-4-nitrobenzene, it has made great achievements in the fields of medicine, agrochemical and materials, and is sincerely a useful product.
Research & Development
In recent years, in the field of organic synthesis, 1,3-difluoro-4-nitrobenzene has gradually become the focus of our chemical researchers. Its structure is unique, and the position of fluorine and nitro groups gives it a different activity.
At the beginning, the preparation method was still simple, and the yield was also low. We worked hard to explore various paths. Or change the reaction agent, or adjust the temperature and pressure, after several years, we can improve. The new method, the yield is gradually increasing, and the purity is also good.
However, the road to its application is not smooth. In drug synthesis, it is difficult to use it to build a special agent, but it is difficult to adapt. Material research and development, hoping to add energy to it, also encounter the difficulty of integration.
We have not dared to slack off and study day and night. With wisdom and perseverance, we hope to break through many difficulties, so that 1,3-difluoro-4-nitrobenzene will shine on the road of research and application, promote the progress of the chemical field, and benefit the world.
Toxicity Research
The nature of the taste of things is related to the use and harm. Now look at the toxicity of 1,3-difluoro-4-nitrobenzene, which is an important matter.
Fu 1,3-difluoro-4-nitrobenzene, color or with its own special. However, its toxicity potential cannot be ignored. After various tests, it can be known that it may invade the body of organisms. Entering the body of animals, it damages the function of the viscera and disrupts the operation of qi and blood. It also has the ability to destroy cells, causing cell abnormalities and dysfunction.
In the environment, if this thing escapes, it will harm all living things. Although it is required for the chemical industry, when it is prepared and used, it must strictly abide by the regulations to prevent it from leaking and harming. To study its toxicity, in order to reduce its harm, ensure the safety of all beings and the environment, this is the heavy responsibility of our generation of chemical researchers.
Future Prospects
1,3-Difluoro-4-nitrobenzene is also an important product in chemistry. At present, science and technology are changing day by day, and the use of this product in various fields is becoming more and more extensive. Although it is now or only seen in several industries, but looking forward to the future, its prospects are really impressive.
In the field of materials, it is expected to use its properties to make new materials, with special quality, suitable for cutting-edge technology. And in the way of pharmaceutical research and development, or with its structure, it can explore the way of new agents and solve the disease of patients.
Furthermore, with the rise of green chemistry, it is the future trend to study the new manufacturing technology of this product, reduce pollution and increase efficiency. In my opinion, with time, 1,3-difluoro-4-nitrobenzene will be used in the forest of chemical industry to rejuvenate its brilliance and develop its grand path. It will contribute to the future's business and become an extraordinary career.
Where to Buy 1,3-Difluoro-4-Nitrobenzene in China?
As a trusted 1,3-Difluoro-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Difluoro-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-difluoro-4-nitrobenzene?
The main use of 1,3-diene-4-cyanobenzene is particularly important. This substance is often used as a key intermediate in the field of organic synthesis. Due to its unique structure, it contains conjugated dienes and cyanobenzene groups, which can be used to construct complex organic structures through various chemical reactions.
In materials science, 1,3-diene-4-cyanobenzene also has wonderful uses. Polymer materials with specific properties can be prepared by polymerization. Such materials may have excellent mechanical properties, thermal stability, or unique properties in optics and electronics, so they are valuable in the research and development of advanced materials, such as high-performance plastics, optoelectronic device materials, etc.
Furthermore, in the field of medicinal chemistry, it can be used as a starting material for the synthesis of many drug molecules. By modifying and derivatizing its structure, or by obtaining biologically active compounds, it is expected to be used in the treatment and prevention of diseases. Its conjugated structure and cyanofunctional group provide rich possibilities for drug molecular design, helping to improve the affinity and selectivity of drugs and targets.
In summary, 1,3-diene-4-cyanobenzene has important uses in many fields such as organic synthesis, materials science, and medicinal chemistry due to its unique chemical structure, providing an indispensable material basis for the development and innovation of related fields.
What are the physical properties of 1,3-difluoro-4-nitrobenzene?
1% 2C3-diene-4-cyanobenzene, its physical properties are quite specific. This substance is mostly in a liquid state at room temperature, and it is clear and has a certain fluidity. It is like smart water, but it is not as pure and clear as water, but has its own unique texture.
Its color is often almost colorless and transparent, and under the light, there are occasional light and shadows that are slightly refracted, just like a touch of agility hidden in the ordinary. Smell it, there is a special smell, not a rich fragrance, nor a pungent smell, but a unique smell of a unique chemical substance, just like a mysterious smell under the precipitation of time.
Furthermore, the density of 1% 2C3-diene-4-cyanobenzene is slightly higher than that of ordinary water. When placed in water, it sinks slowly, showing the characteristics brought by its own density. And its boiling point and melting point are fixed. The boiling point can boil into a gaseous state at a specific temperature, and the melting point also solidifies from a liquid state to a solid state at a specific low temperature. These two temperature values are important characterizations of its physical properties.
In addition, the solubility of this substance also has characteristics. In some organic solvents, such as water, it can be evenly dispersed and dissolved, showing good miscibility; however, in water, it is difficult to blend, just like the barrier between oil and water, clear and clear. These differences in solubility are important considerations in practical applications and research. The physical properties of 1% 2C3-diene-4-cyanobenzene are so various and intertwined that they together constitute the unique physical appearance of 1% 2C3-diene-4-cyanobenzene. In many fields such as chemical industry and scientific research, they have specific uses and significance due to their properties.
What are the synthesis methods of 1,3-difluoro-4-nitrobenzene?
There are many synthesis methods of 1% 2C3-diethyl-4-cyanopyridine. The following is a detailed description for you.
One is the method of using pyridine as the starting material. First, pyridine is reacted with halogenated ethane in a strong alkali environment to introduce ethyl group to generate the corresponding ethylpyridine derivative. After that, cyanide is introduced into the molecule through a suitable cyanide reagent, such as potassium cyanide, under specific conditions, so as to achieve the synthesis of 1% 2C3-diethyl-4-cyanopyridine. This path step is relatively clear, but the regulation of the reaction activity of pyridine derivatives needs to be carefully grasped, and the cyanide reaction conditions are strict, which requires high safety operation.
The second can start from simple compounds containing ethoxy and cyano groups. For example, the condensation reaction of nitrile compounds substituted with suitable ethoxy groups with pyridine derivatives is carried out. Under the action of appropriate catalysts, a series of reactions such as condensation and cyclization are carried out to finally generate the target product. The key to this method is to optimize the condensation reaction conditions, including the selection of catalysts, the control of reaction temperature and time, in order to improve the yield and selectivity.
The third is the method of using transition metal catalysis. Using halogenated pyridine derivatives, halogenated ethane and cyanide reagents as raw materials, under the catalysis of transition metal catalysts such as palladium catalysts, the construction of carbon-carbon bonds and carbon-nitrogen bonds can be realized, and 1% 2C3-diethyl-4-cyanopyridine can be synthesized in one or more steps. Such methods have the advantages of high efficiency and good selectivity, but transition metal catalysts are expensive and the reaction cost is high, and the recovery and reuse of catalysts are also problems that need to be solved.
Each synthesis method has its own advantages and disadvantages. In practical application, many factors such as the availability of raw materials, cost, reaction conditions and product purity need to be considered comprehensively, and the most suitable synthesis path should be selected.
What are the precautions for storing and transporting 1,3-difluoro-4-nitrobenzene?
1% 2C3-diethyl-4-cyanobenzene needs to be carefully attended to in all matters of storage and transportation.
First, this material is chemically active, and the environment must be kept stable during storage and transportation. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. If it is in a high temperature or humid environment, it may cause chemical reactions, cause material deterioration, and even cause safety risks.
Second, its packaging must be tight. The quality of the packaging should be resistant to corrosion and well sealed to prevent leakage. If it leaks, it will not only damage the substance itself, but also cyanobenzene is toxic, or pollute the environment, endangering the surrounding people and animals. When handling, it should also be handled with care to avoid damage to the packaging.
Third, the stockist must clarify its characteristics and emergency response methods. Knowing its chemical properties, you can take appropriate measures in the event of an emergency. If there is a leak, evacuate the crowd immediately, prohibit unrelated people from approaching, and adopt effective collection and cleaning methods to dispose of the waste in accordance with relevant regulations.
Fourth, follow the regulations. Storage and transportation of chemical substances must be carried out in accordance with national and local laws. From the application for permits to the operating specifications, you must not exceed the rules. If you violate it, you will not only be punished, but also lose control safely.
In short, the storage and transportation of 1% 2C3-diethyl-4-cyanobenzene requires strict preparation in terms of environment, packaging, personnel knowledge and regulatory compliance, and must not be slack at all to ensure the safety of the process.
What are the effects of 1,3-difluoro-4-nitrobenzene on the environment and human health?
1,3-Diene-4-cyanobenzene. The effect of this substance on the environment and human health is quite complex.
At the environmental end, it may have some potential effects. If it is released into the atmosphere, its chemical structure or participates in photochemical reactions, it will play a role in the generation and reaction process of free radicals in the atmosphere, which in turn affects the delicate balance of atmospheric chemistry. Its migration and transformation between soil and water bodies also need to be carefully investigated. In soil, or adsorbed on soil particles, it affects the activity and composition of soil microbial communities. Due to its special structure, it may be toxic to some microorganisms and disturb the normal function of soil ecosystems. In water bodies, or dissolved and dispersed, it poses a threat to aquatic organisms. The cyanide group in its structure is toxic to a certain extent, or causes damage to the physiological functions of aquatic organisms such as fish and plankton, affecting their reproduction, growth and survival, and destroying the biodiversity of aquatic ecosystems.
As for human health, there are also potential hazards. Inhalation through the respiratory tract, or irritation of respiratory mucosa, can cause discomfort such as cough and asthma. Under long-term exposure, because it contains unsaturated bonds and cyanide groups, it may have a certain risk of mutation and carcinogenesis. It enters the human body through skin contact or penetrates the skin barrier, interfering with normal biochemical reactions in the body, affecting cell metabolism and function. If ingested carelessly, cyano can release toxic cyanide ions in the body, inhibit the activity of key enzymes in cell respiration, hinder the use of oxygen by cells, lead to hypoxia of tissues and organs, and cause danger to life.
1,3-diene-4-cyanobenzene poses a potential threat to the environment and human health, and it needs to be properly controlled to reduce its negative effects.