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1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene

1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    499496

    Chemical Formula C7H2F5NO2
    Molecular Weight 227.09

    As an accredited 1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1,3 - difluoro - 4 - nitro - 2 - (trifluoromethyl)benzene in sealed chemical - grade bottle.
    Storage 1,3 - Difluoro - 4 - nitro - 2 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage and contamination. Avoid storage near incompatible substances.
    Shipping 1,3 - difluoro - 4 - nitro - 2 - (trifluoromethyl)benzene is a chemical. It should be shipped in accordance with hazardous chemical regulations, using appropriate packaging to prevent leakage and ensure safe transportation.
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    1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene 1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1,3-Difluoro-4-nitro-2- (trifluoromethyl) benzene is an important product of chemistry. At the beginning of its origin, when the exploration of chemistry was first flourishing, all the sages exhausted their wisdom to study new substances. Although the synthesis of this product was difficult at the beginning, the craftsmen were reluctant to give up their pursuit.
    With the passage of time, the chemical technology has become more and more exquisite. The complicated steps in the past were gradually simplified, and the raw materials were more convenient. People have repeatedly explored in the way of experiments, modified the synthesis method, and made its yield gradually increase.
    As for today, this product is used in many fields such as chemical industry and medicine. Looking at its historical evolution, it is like a pearl in the long river of chemistry, becoming more and more brilliant, witnessing our generation's unremitting exploration and progress in science.
    Product Overview
    1,3-Difluoro-4-nitro-2- (trifluoromethyl) benzene is a chemical product we have studied. Its color is pure and pure, and its molecular structure is specific. It is cleverly connected by fluorine, nitro and trifluoromethyl. This product has a wide range of uses in chemical fields and can be used as a key raw material for organic synthesis. In specific reactions, it is often the key substance that lays the foundation. It can be converted multiple times to derive many high-value products. Its physical properties are also unique. The melting point, boiling point and other data are accurate, providing exact guidance for practical application. Good stability, under conventional conditions, it can maintain its inherent characteristics. However, in specific environments, it also needs to be handled with caution to prevent accidents. I will explore it in depth, hoping to expand its application scope and contribute to the development of the chemical industry.
    Physical & Chemical Properties
    1,3-Difluoro-4-nitro-2- (trifluoromethyl) benzene, this material has special properties. Its color may be light and clear, and its shape is like a flowing liquid. It exists stably at room temperature. Its boiling point is fixed, reaching a certain value, and varies slightly depending on the surrounding air pressure. As for the melting point, it is also a characteristic, and the shape changes between specific temperatures.
    Looking at its chemistry, it has a lively quality. Nitro exists in the structure, causing its aerobic properties. When encountering suitable agents, it can react, change its structure, and produce new compounds. The genus of trifluoromethyl increases its ability to dissolve lipids and dissolves well in organic solvents. And the difluorine atom, in turn, changes its electron cloud, affecting the reaction path.
    The study of this physical property is of great significance in the field of chemical industry. Or it can be used to create new drugs, with its special properties, into specific targets, and treat human diseases. Or it can be used for the creation of new materials, giving them special properties, and meeting diverse needs.
    Technical Specifications & Labeling
    1,3-Difluoro-4-nitro-2- (trifluoromethyl) benzene is also a chemical that we have dedicated ourselves to researching. Its process specifications and identification (product parameters) are the key.
    The process specifications of this product need to be handled in a precise and strict manner. From the selection of raw materials, it is necessary to be pure and flawless, and to meet specific regulations. During the reaction, various conditions such as temperature and pressure should be precisely controlled, and a slight mistake will damage the quality.
    As for the identification (product parameters), it must also be clear and correct. The proportion of the elements contained, the value of purity, as well as the properties, melting point, boiling point, etc. should be recorded in detail. In this way, the user can make good use of it according to its characteristics.
    Our chemical researchers, with caution and strict adherence to process specifications, accurately establish the identification (product parameters) for the quality and application of 1,3-difluoro-4-nitro-2 - (trifluoromethyl) benzene, and make every effort.
    Preparation Method
    To prepare 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene, the method is as follows:
    Raw materials and production process: Take an appropriate amount of fluorine, nitro and methyl compounds as the initial raw materials. Compatibility in a specific ratio, prepared by multi-step reaction.
    Reaction steps: The first step is to make the raw materials at a suitable temperature and pressure, under the action of a specific catalyst, a substitution reaction occurs, and fluorine atoms are introduced. In the second step, the reaction conditions are finely regulated, the nitrification reaction is carried out, and the nitro group is precisely positioned. Then through a special process, trifluoromethyl is introduced.
    Transformation mechanism: Each step of the reaction follows a specific chemical principle, and the substitution reaction is based on the activity of the reactants and the affinity The nitrification reaction uses a specific catalyst to guide the nitro group to the target position. The introduction of trifluoromethyl groups uses unique reagents and reaction conditions to achieve precise atomic conversion, resulting in the efficient preparation of 1,3-difluoro-4-nitro-2 - (trifluoromethyl) benzene.
    Chemical Reactions & Modifications
    Nowadays, there is a substance named 1,3-difluoro-4-nitro-2 - (trifluoromethyl) benzene, which is very important in chemical research. Its chemical reaction and modification have been studied by many scholars.
    Looking at the reaction of this compound, the conditions are different, and the products are different. Or at a certain temperature and pressure, when it encounters a certain reagent, it undergoes substitution, functional group translocation, and structural change.
    As for modification, it is designed to adjust its performance. Or increase its stability, making it difficult to decompose in complex environments; or change its activity, making the reaction easier to control. This is the gist of chemical research. After many attempts, scholars hope to use their insights into its reaction and modification to expand the application of this substance in materials, medicine and other fields, so as to benefit the world.
    Synonyms & Product Names
    Today there is a thing named 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene. This thing is very important in our chemical research. It also has many synonymous names and commodity names.
    The names of its synonyms are all given by chemists to accurately describe its chemical structure and properties. Either according to the arrangement of its atoms or according to the characteristics of its functional groups, each has its own wonders. And the name of the commodity is for the convenience of market circulation and merchants. It may show unique properties or contain commercial implications.
    When studying this substance, our chemists need to clarify its synonymous names and commodity names in order to communicate accurately and promote research. In the laboratory, to discuss its reaction mechanism and analyze its physicochemical properties, it is inseparable from the familiarity of the names of this substance. We also hope that future generations can explore the mysteries of this substance more deeply on the basis of our research, and contribute to the development of chemistry.
    Safety & Operational Standards
    Specifications for the safety and operation of 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene
    For 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene, it is also a new product. Its unique nature is related to safety and operation, and it must be subject to detailed regulations.
    In terms of safety, this material may be dangerous. When hiding, it should be placed in a cool and dry place, away from open flames and hot topics. If it is exposed to heat or explosion, it will cause catastrophe. It must also be kept away from strong oxygen agents and strong acids and alkalis to prevent its transformation from being dangerous.
    If someone touches it, wash it with large water urgently. If there is any injury, get a doctor as soon as possible. If it enters the eyes, flush it immediately with water or raw salt liquid, and also seek medical attention. If you inhale by mistake, go to a new place as soon as possible. If it is difficult to rest, apply artificial respiration and seek medical attention.
    Under the rules of operation, the operator must receive special training and be on guard. When exercising, it is appropriate to wear protective clothing, goggles and anti-poison equipment to avoid air and fog entering the body.
    The device must be grounded to prevent static combustion. When taking it, measure it carefully and do not sprinkle too much. After the operation, clean the device and the field, and keep the ring clean.
    Anyone involved in this matter should take the lead and follow the rules. In this way, you can avoid trouble and ensure people's safety and prosperity.
    Application Area
    1,3-Difluoro-4-nitro-2- (trifluoromethyl) benzene, the field of its use is quite involved. In medicine, it can be used as the raw material of medicine to help treat various diseases. Because of its unique nature, it can enter the focus and adjust the body's ability. In the industry of agriculture and planting, it can be used as an agricultural agent to prevent diseases and insect pests and protect the growth of seedlings. It is also used in fine chemicals to make special materials and excipients. Its use in various fields has gradually become more and more important. According to an ancient saying: "This chemical quality can be used in medicine, agriculture, and chemistry. It can help doctors heal diseases and cure people's diseases; it can assist farmers to protect seedlings and make crops rich; it can also be the foundation of chemical industry, creating strange materials and special things, and it can benefit the world. "
    Research & Development
    In recent years, 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene has been studied for its unique properties and wide uses. At first, analyze its structure, observe the conformation of its molecules, and know the formula of its atomic connection. Then explore the method of its synthesis, try various paths, and find the way of high efficiency and purity.
    Under the reaction conditions, carefully consider the factors of temperature, pressure, and catalyst. After repeated tests, the best environment is obtained, which greatly increases the yield and quality.
    And the field of application of this substance is studied. In medicine, it can be used as an intermediate to help create new drugs; in materials, it can change its properties and expand its uses. Looking at it, the research of 1,3-difluoro-4-nitro-2 - (trifluoromethyl) benzene has broad prospects and will surely shine in various fields in the future, promoting the progress of science and technology and promoting the prosperity of the industry.
    Toxicity Research
    In modern times, chemistry has flourished, and the study of the properties of various things has deepened. Today there is a thing named 1,3-difluoro-4-nitro-2 - (trifluoromethyl) benzene, and the study of its toxicity is quite important.
    Looking at this substance, it has a unique structure and contains fluorine, nitro and other groups. Fluorine is active and often modifies; nitro is also strongly oxidizing. The two are combined in a benzene ring, and their toxicity is abnormal.
    To understand its toxicity, it should be tested on living things. First, try it with insects to observe its behavior and growth changes. Then use mice and other animals to observe its physiological functions and organs. It is toxic if the insects are wilted, the mice are unwell, or the organs are damaged.
    It is also necessary to study the state of this substance dispersing and degrading in the environment. If it is difficult to degrade and widely distributed, it will be dangerous to the ecology. We chemical researchers must carefully investigate its toxicity, avoid harm and profit when using this substance for the world, and protect the environment and personal safety.
    Future Prospects
    I have been researching 1,3-difluoro-4-nitro-2 - (trifluoromethyl) benzene for a long time. This compound is unique in nature and has a wide range of uses. It has potential in the fields of medicine and pesticides.
    Looking at the present, although there are synthetic methods, there is still a huge room for optimization. I hope to find simpler and more efficient methods in the future to reduce costs and yield, making its preparation more convenient.
    And the exploration of its derivatives has not been completed. It is hoped that in the future, a variety of new compounds can be derived and the application scope can be expanded. Or emerge in the research and development of new materials, contributing to the progress of science and technology.
    With environmental protection in mind, I hope the synthesis path can be greener, reduce pollution, and conform to the way of nature. In this way, the future of 1,3-difluoro-4-nitro-2 - (trifluoromethyl) benzene will be bright, shining in various industries, and seeking endless benefits for human well-being.
    Where to Buy 1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene in China?
    As a trusted 1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,3-Difluoro-4-Nitro-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene?
    1% 2C3-diene-4-cyano-2- (trienomethyl) benzene, which has a wide range of uses. In the field of medicinal chemistry, it can be used as a key intermediate to synthesize drug molecules with specific biological activities. By modifying and modifying its structure, compounds with high affinity and selectivity for specific disease targets can be obtained, such as the development of anti-tumor and anti-viral drugs, which help overcome medical problems and bring good news to patients.
    In the field of materials science, it can be used to prepare functional polymer materials. Due to its unique molecular structure, it can endow polymer materials with properties such as good optical properties and thermal stability. For example, by introducing it into polymer systems, the resulting materials may be applied to optoelectronic devices, such as organic Light Emitting Diodes (OLEDs), to improve the luminous efficiency and stability of the device, and to promote the progress of display technology.
    In organic synthetic chemistry, as a highly active organic reagent, it can participate in a variety of chemical reactions, such as cyclization reactions, addition reactions, etc., providing an effective way to construct complex organic molecular structures, enabling organic chemists to create organic compounds with novel structures and unique properties, expanding the research boundaries of organic chemistry, and laying the foundation for the development of new materials and new drugs.
    What are the physical properties of 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene?
    1% 2C3-diene-4-cyano-2- (trienyl methyl) benzene is one of the organic compounds. Its physical properties are diverse and it plays an important role in the chemical industry.
    Looking at its physical state, under normal temperature and pressure, this compound is often in a liquid state. Its texture is relatively viscous, and it flows slowly like a stream, with a certain fluidity. However, compared with common fluids such as water, its flow is slightly stagnant.
    When it comes to color, it is mostly colorless and transparent, like a pure crystal, clear and free of impurities. Under light, it can refract bright light.
    Smell its smell and exude a unique aromatic smell. However, the aroma is not rich and pungent, but milder, seemingly absent, but clearly recognizable.
    Its melting point and boiling point are also key physical properties. The melting point is about [specific value] ° C. When the temperature drops below the melting point, the substance will gradually solidify from liquid to solid state, and the molecular arrangement will change from disorder to order. The boiling point is about [specific value] ° C. If the temperature rises to the boiling point, the substance will change from liquid to gaseous state sharply, and the molecular movement will become more intense and break free from each other.
    In terms of density, it is slightly heavier than water. If it is mixed with water, it will slowly sink to the bottom of the water, like a stone sinking into an abyss.
    In terms of solubility, it has good solubility in common organic solvents such as ethanol and ether, and can be uniformly mixed with these solvents to form a uniform solution; in water, its solubility is poor, just like oil dripping into water, it is difficult to blend.
    In addition, the stability of the compound cannot be ignored. Under normal conditions, it has a certain stability and can exist relatively stably; however, in case of special conditions such as high temperature and strong oxidants, its chemical structure may change, triggering a series of chemical reactions.
    What are the chemical properties of 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene?
    1% 2C3-diene-4-cyano-2- (trienyl methyl) benzene is an organic compound. Its chemical properties are quite complex and contain unique characteristics. Let me analyze it in detail for you.
    In this compound, the 1% 2C3-diene structure endows it with remarkable conjugate properties. The conjugate system allows the electron cloud to be delocalized, which in turn has a significant impact on the stability of the compound and the properties of the electron spectrum. The conjugate structure often enhances the stability of the molecule and plays a key role in the process of light absorption and emission, resulting in the compound may exhibit unique optical properties.
    4 -cyano functional group is also of great significance. Cyanyl groups are strong electron-absorbing groups, which affect the distribution of electron clouds in molecules and change the polarity of molecules. This property affects the physical properties of compounds, such as boiling point, melting point and solubility. At the same time, cyanyl groups are often a key reaction check point in the field of organic synthesis, and can participate in a variety of chemical reactions, such as hydrolysis to form carboxylic acids, and addition reactions with nucleophiles.
    The 2 - (trienyl) part also adds unique properties to the molecule. The introduction of trienyl groups changes the spatial structure and electronic effects of molecules, and affects the interactions between molecules. Its steric blocking effect may affect the reactivity and selectivity of compounds. In chemical reactions, spatial factors often play a decisive role in the process of reactions and the generation of products.
    In addition, from the perspective of the overall molecular structure, the functional groups interact and cooperate with each other. The electronic effects between the conjugated system and the cyano group and the trienyl methyl group are intertwined to further shape the chemical properties of the compound. This compound may show potential application value in the fields of organic synthesis and materials science. For example, as a key intermediate for the construction of new functional materials, it is used in frontier fields such as optoelectronic materials with its unique electronic and optical properties.
    In summary, the chemical properties of 1% 2C3-diene-4-cyano-2 - (trienomethyl) benzene are determined by the synergy of its various parts, presenting rich and unique characteristics, which hold broad research and application prospects in many fields.
    What are the synthesis methods of 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene?
    The synthesis method of 1% 2C3-diene-4-cyano-2- (trienomethyl) naphthalene can have the following methods:
    First, naphthalene is used as the initial raw material. First, a specific substitution reaction is carried out on the naphthalene, and an appropriate substituent is introduced to activate the specific position of the naphthalene ring. Selective halogenation is carried out on the naphthalene ring through carefully selected halogenation reagents to prepare for the subsequent construction of the diene and cyanyl structures. Then, with the help of metal-organic reagents, such as Grignard reagent or lithium reagent, the halogenated naphthalene is reacted to introduce the structural fragment containing the alkenyl group. At the same time, the cyanide group is introduced at the appropriate position through a nucleophilic substitution reaction using When constructing the diene structure, classical methods such as Wittig reaction or Horner-Wadsworth-Emmons reaction can be selected. The 1% 2C3-diene structure can be accurately generated by the reaction of aldehyde or ketone with phosphonylide or phosphonate.
    Second, start from a simple compound containing alkenyl groups and cyanyl groups. A suitable alkenyl halide is reacted with a nucleophile containing a naphthalene ring structure to form a carbon-carbon bond, and the surrounding structure of the naphthalene ring is gradually constructed. In this process, the protective group strategy is cleverly used to protect the sensitive group and avoid unnecessary changes in the reaction. After the surrounding structure of the naphthalene ring is basically completed, the active group is released through deprotection reaction, and further through condensation, cyclization and other reactions, a complete 1% 2C3-diene-4-cyano-2 - (trienyl methyl) naphthalene structure is constructed.
    Third, the coupling reaction catalyzed by transition metals is used. With halogenated naphthalene derivatives and alkenyl borate or alkenyl halide as raw materials, Suzuki coupling or Heck coupling reaction occurs under the action of transition metal catalysts such as palladium and nickel, and carbon-carbon double bonds can be efficiently constructed. At the same time, the precise introduction of cyanyl and trienyl methyl can be realized by controlling the appropriate reaction sequence and conditions. During the reaction process, the reaction conditions such as reaction solvent, type and amount of base, and catalyst loading need to be carefully regulated to improve the selectivity and yield of the reaction.
    What are the precautions for storing and transporting 1,3-difluoro-4-nitro-2- (trifluoromethyl) benzene?
    1% 2C3-diene-4-cyano-2- (trienyl methyl) benzene, when storing and transporting, need to pay attention to many matters.
    First, because of its active chemical properties, it has strict requirements on the temperature and humidity of the storage environment. It should be placed in a cool, dry and well-ventilated place, and the temperature should be maintained within a specific range to prevent chemical reactions caused by excessive temperature, resulting in deterioration of the substance, and even possible danger. Humidity also needs to be strictly controlled. Excessive humidity may cause it to be damp, which will affect the quality.
    Second, when transporting, be sure to ensure that the packaging is tight and firm. Appropriate packaging materials should be selected, which should have good sealing and protective properties to resist external physical impact and chemical attack, and prevent material leakage.
    Third, this substance may have certain toxicity and irritation, storage and transportation places should be away from crowded areas, and there should be significant warning signs to alert everyone. Operators need to wear professional protective equipment, such as protective clothing, gloves, protective masks, etc., to avoid direct contact with them.
    Fourth, in view of its chemical properties, it should be avoided with oxidizing substances, acidic substances, alkaline substances and other co-storage and transportation. Because of its violent chemical reaction with these substances, dangerous accidents can occur.
    Fifth, during storage and transportation, a complete monitoring and emergency response mechanism should be established. Regularly check the status of the substance, and if any abnormalities are detected, such as damaged packaging, abnormal odor, etc., emergency measures must be initiated immediately to reduce the harm.