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1,3-Difluoro-2-Nitrobenzene

1,3-Difluoro-2-Nitrobenzene

Hongda Chemical

Specifications

HS Code

220187

Chemical Formula C6H3F2NO2
Molar Mass 159.09 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 214 - 216 °C
Melting Point 2 - 4 °C
Density 1.448 g/cm³
Flash Point 90 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Logp Around 2 (estimation for lipophilicity)

As an accredited 1,3-Difluoro-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,3 - difluoro - 2 - nitrobenzene in 1 - kg bottles, well - sealed for chemical storage.
Storage 1,3 - Difluoro - 2 - nitrobenzene should be stored in a cool, well - ventilated area away from heat and ignition sources. It should be placed in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other incompatible substances. Adequate storage facilities should be provided to handle potential spills safely.
Shipping 1,3 - Difluoro - 2 - nitrobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and environmental or safety risks during transit.
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1,3-Difluoro-2-Nitrobenzene 1,3-Difluoro-2-Nitrobenzene
General Information
Historical Development
1,3-Difluoro-2-nitrobenzene is also an important chemical product. At the beginning, the synthesis method was not good, the yield was quite low, and there were many impurities. However, the researchers were lax, and they tried their best to explore the reason. After several years, the technique has gradually refined, the yield has risen, and the quality has become purer. At first, it was a crude method, but very little was obtained. Later, it was improved, with new agents and new machinery, and the system was orderly. In the past, the synthesis was difficult, such as involving dangerous beaches, but now it is popular, and it has shown its ability in the fields of medicine and materials, and it is used more and more widely. From this perspective, the development of this thing depends on the diligence of the researchers, starting from the end of the micro, and has become prosperous today. It can be said to be the work of science and technology, making it move forward steadily in the chemical industry, with bright prospects.
Product Overview
1,3-Difluoro-2-nitrobenzene is also a chemical that I have studied with great care. What is its shape? Looking at it, it is a colorless to light yellow liquid with a clear texture. Smell it, it has a specific smell, although it is not very strong, it cannot be ignored.
The properties of this product are lively and changeable. In its molecular structure, fluorine atoms coexist with nitro groups, fluorine atoms have high electronegativity, and nitro groups have strong electron absorption. The interaction between the two makes the product highly chemically active. In the field of organic synthesis, it is often a key intermediate. It can be obtained through various reactions such as halogenation and nitrification. It plays a significant role in the preparation of fine chemicals such as pharmaceuticals and pesticides, and can pave the way for the creation of new compounds. It is an indispensable material for chemical research and industrial production.
Physical & Chemical Properties
1,3-Difluoro-2-nitrobenzene is an important substance for chemical research. Its physical properties are unique. Looking at it, it is a colorless to light yellow liquid at room temperature. It smells and has a special odor. Its boiling point is suitable, and it boils in a specific temperature range, which is conducive to separation and purification. Melting point is also one of its characteristics, which are all related to its physical state changes.
In terms of its chemical properties, it is highly active due to the presence of fluorine, nitro and other functional groups. The electronegativity of fluorine atoms is strong, causing the electron cloud density of the benzene ring to change, and the nitro group also has strong electron absorption. The synergy between the two makes the substance prone to nucleophilic substitution. In many chemical synthesis pathways, this property is the key, or in the field of medicine, pesticide creation, etc., play an indispensable role, and it is an object that cannot be ignored in the field of chemical research.
Technical Specifications & Labeling
1,3-Difluoro-2-nitrobenzene technical specifications and labeling (product parameters)
Fu 1,3-difluoro-2-nitrobenzene is an important chemical product. Its technical procedures are crucial. In the preparation process, specific steps and conditions must be strictly followed. The raw materials must be selected well and the proportions must be accurately prepared. During the reaction, factors such as temperature and pressure must be carefully controlled, so that high-purity products can be obtained.
As for the labeling, the product parameters should be clearly marked. Such as purity, specific standards should be met, and the impurity content must be strictly limited. The appearance color should also be clear to ensure that the user can accurately distinguish. And on the packaging, all kinds of warning signs are indispensable to prevent accidents and ensure safe operation. In this way, the technical regulations and labeling specifications of this object are also combined.
Preparation Method
In order to prepare 1,3-difluoro-2-nitrobenzene, the method is as follows:
In terms of raw materials, select the appropriate starting reactant, which is the basis for preparation. In the synthesis process, through specific reaction steps. First make a reactant react according to specific conditions and change its structure. For example, starting with benzene derivatives, fluorine atoms are introduced through halogenation reaction, and precise control of the reaction temperature, time and ratio of reactants is one of the keys.
Subsequent nitrification reaction is added with nitro groups. During the reaction process, pay attention to the pH of the reaction environment and the use of catalysts. In this series of reaction steps, each step is closely linked, and the effect of one step is related to the follow-up.
and need to build a reasonable monitoring mechanism. After each step of the reaction, the purity and structure of the product can be detected by analytical means. If there is any deviation, the subsequent steps can be adjusted in time. In this way, it is expected to produce 1,3-difluoro-2-nitrobenzene efficiently and with high quality.
Chemical Reactions & Modifications
There is now a substance named 1,3-difluoro-2-nitrobenzene. In the field of chemistry, its reaction and modification are worth exploring.
For chemists, if they want to understand its properties, they must study its reaction. 1,3-difluoro-2-nitrobenzene, in case of nucleophiles, fluorine atoms can be replaced. This is because of the electron-withdrawing property of the nitro group, which causes the electron cloud density of the benzene ring to change. Nucleophiles, such as alkoxides and amines, can interact with it to generate new compounds.
As for modification, the method of reducing nitro groups can be used. With an appropriate reducing agent, the nitro group is changed to an amino group, so that a new substance containing an amino group can be obtained, and its properties and uses are different from before. Or modify the substituents on the benzene ring to adjust their electronic effects and spatial effects to meet different needs.
The beauty of chemistry lies in the ability to change substances, creating unprecedented things. Exploring the reaction and modification of 1,3-difluoro-2-nitrobenzene may open up new avenues for the research of new materials and new drugs.
Synonyms & Product Names
1,3-Difluoro-2-nitrobenzene is also a chemical substance. Its synonyms are diverse and complex, and it is quite important in the industry. This compound has many aliases, but they all refer to the same thing.
Looking at various ancient books, its names are different. Or because of its characteristics, or according to the method of synthesis, the names are different. The names of chemical substances often vary from time to place, but their essence remains unchanged. 1,3-Difluoro-2-nitrobenzene, in the chemical industry, has a wide range of uses. Its trade names are also many, and each merchant names it according to his own rules. However, they are all for the convenience of the market and attract attention.
We chemical researchers should carefully identify their names and make it clear that they refer to the same thing. No matter what the name is, we should understand its nature, make good use of its capabilities, and do our best for the progress of chemistry. Only in this way can we continue to move forward in the path of chemistry, explore its mysteries, and seek the well-being of the world.
Safety & Operational Standards
1,3-Difluoro-2-nitrobenzene is a chemical that I have recently studied. The safety and operation specifications of this substance are of great importance and need to be investigated in detail.
F 1,3-difluoro-2-nitrobenzene has specific chemical properties. It is active and can be used as a key raw material in many chemical reactions. However, due to its active nature, it is necessary to be cautious when operating.
When it comes to safety, store it first. Keep it in a cool, dry and well-ventilated place, away from fire and heat sources. Because it is exposed to open flames and hot topics, it may risk combustion and explosion. Packaging must also be tight to prevent leakage. If it leaks carelessly, it must be disposed of quickly according to the regulations, so as not to spread, causing environmental pollution and personal harm.
When operating, there are also many regulations. Operators must be professionally trained and familiar with the operation process. During operation, wear protective clothing, protective gloves and goggles to prevent contact with the skin and eyes. It is best to operate in the fume hood, so that the volatile gas can be discharged in time, so as not to be inhaled into the human body.
Furthermore, in the process of using 1,3-difluoro-2-nitrobenzene, it is necessary to precisely control the reaction conditions. Temperature, pressure, proportion of reactants, etc., must be strictly controlled. A slight poor pool, or cause the reaction to go out of control, endangering safety.
Waste disposal cannot be ignored. Do not discard at will, and must be properly handled in accordance with environmental regulations to ensure that it is harmless to the environment.
In short, the safety and operation practices of 1,3-difluoro-2-nitrobenzene are related to personal safety, environmental protection and the success or failure of experiments or production. Our chemical researchers must strictly abide by the norms and operate cautiously in order to achieve the purpose of scientific research and production without worries.
Application Area
1,3-Difluoro-2-nitrobenzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help many specific drugs. For example, some antibacterial agents, with their unique structure, undergo complex reactions to achieve high antibacterial performance.
In the context of material science, it also has its own uses. It can participate in the creation of new materials, so that the materials have special electrical and optical properties. For example, it can help develop materials that are sensitive to specific wavelengths of light for optoelectronic devices.
Furthermore, it is also an important component in the preparation of pesticides. It can be derived from pesticides with strong insecticidal and weeding effects, protect farmland crops, and ensure a bumper harvest. All these show that 1,3-difluoro-2-nitrobenzene is indispensable in various application fields.
Research & Development
Modern chemistry is refined, and the categories are prosperous. 1,3-difluoro-2-nitrobenzene is gradually becoming more and more important in various fields.
I have devoted myself to studying its properties and exploring its preparation method. Looking at its physical properties, it is clear that its color state, number of melting boils, and the characteristics of its solubility. Chemistry, exploring its reaction mechanism, such as nucleophilic substitution and reduction changes, are all subject to detailed examination.
The study of the production method involves both ancient methods and new methods. Although the old method has a foundation, it may consume a lot, the yield is small, or it may be polluted in the environment. Think about the way of innovation, introduce new agents, optimize the process, and hope to improve the yield and reduce pollution.
As for the application, the prospect is also broad. In the synthesis of medicine, it can be a key intermediate to help the creation of new drugs; in the field of materials, it can also add its properties.
In the future, we should continue to deepen our cultivation, hope to expand our applications, optimize our processes, and contribute to the development of chemistry and industry.
Toxicity Research
In modern times, chemistry has flourished, and all kinds of substances have been included in the research. Today, there is 1,3-difluoro-2-nitrobenzene, and toxicity research is of paramount importance.
Looking at its structure, fluorine and nitro are combined with the benzene ring. Fluoride is active and has special effects; nitro groups also have strong chemical activity, and the two coexist, which may cause extraordinary toxicity.
Experiments have found that in biological systems, it may disturb the normal metabolism of cells and disrupt their physiological order. Oral intake may harm the digestive system; percutaneous absorption can also damage the skin and internal tissues.
Although the current research has gradually clarified the outline of its toxicity, it still needs to be further investigated. In the case of industrial preparation and use, protection measures should not be ignored, and its toxicity must be carefully reviewed to ensure the safety of the survivors and the tranquility of the environment.
Future Prospects
1,3-Difluoro-2-nitrobenzene is also a chemical substance. In today's world, the research of these substances is also in-depth. I am a researcher of chemical substances, and I often think about its undeveloped development.
1,3-difluoro-2-nitrobenzene has special properties, which can be used as a raw material for multi-chemical reactions. Not yet, or it can be used in the field of new research. With its special properties, or it can help those who can make special effects, it can save the world.
Or in the field of materials, it can be used to make a big impact. It can be based on new materials to make materials have better properties, such as durability and durability. In my hope, I hope that this transformed product will lead to new technologies and promote new technological advancements in the future, so as to benefit the world and become the vision that my researchers hope for.
Where to Buy 1,3-Difluoro-2-Nitrobenzene in China?
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Frequently Asked Questions

As a leading 1,3-Difluoro-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-difluoro-2-nitrobenzene?
1,3-Diene-2-ketonaphthalene is an important organic compound with a wide range of main uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique conjugated double bond and ketone structure, it can participate in various chemical reactions, such as Diels-Alder reaction, which can efficiently construct complex cyclic compounds, which is of great significance for the total synthesis of natural products. Many natural products and bioactive molecules have similar structural fragments. With 1,3-diene-2-ketonaphthalene as the starting material, the synthesis of target molecules can be achieved through a series of reactions.
In the field of materials science, 1,3-diene-2-ketonaphthalene and its derivatives may have special photoelectric properties. The conjugated structure endows it with good electron transport ability and fluorescence properties, which can be used to prepare organic Light Emitting Diodes (OLEDs), organic solar cells and other optoelectronic devices. After chemical modification, its molecular structure and electron cloud distribution are regulated to optimize the photoelectric properties of materials to meet different application needs.
It also has potential value in the field of medicinal chemistry. Some compounds containing 1,3-diene-2-ketonaphthalene structures have been studied to show certain biological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc. Or by interacting with specific targets in vivo, the pharmacological effect can be exerted to provide direction and lead compounds for the development of new drugs. After structure optimization and activity screening, it is expected to develop innovative drugs with high efficiency and low toxicity.
What are the physical properties of 1,3-difluoro-2-nitrobenzene?
The physical properties of 1% 2C3-diene-2-ketonaphthalene are quite unique. Looking at its shape, at room temperature, it is mostly in the shape of a solid state, and the texture is relatively solid, as if it has been condensed over time.
When it comes to color, it often shows a plain color, either white or slightly yellow, just like a clear spring in the mountains, simple and pure.
Smell its smell, faintly emitting a special fragrance, not rich and strong, but fresh and elegant, as if you are in a quiet mountain forest, it has a different charm.
The density of this substance is slightly heavier than that of water. If placed in water, it will slowly sink, just like a calm heart, neither floating nor impatient.
Its melting point also has a specific value. When the outside temperature rises to a certain precise scale, it gradually melts from solid to liquid, just like ice and snow in spring, quietly changing its form.
As for solubility, in organic solvents, such as ethanol, ether, etc., it shows good solubility and can be fused with it; however, in water, it is difficult to dissolve, just like the barrier between oil and water, which is distinct.
In addition, its crystal structure is also unique, and the internal particles are arranged in a regular and orderly manner, like a delicate chess game, containing the wonders of nature. These are the physical properties of 1% 2C3-diene-2-ketonaphthalene, each with its own rhyme, which together outline the unique appearance of this thing.
Is the chemical properties of 1,3-difluoro-2-nitrobenzene stable?
1% 2C3-diene-2-hydroxymethylnaphthalene is stable in properties. It has alkenyl groups and hydroxymethyl groups, and its structure is special. The alkenyl group is active and can participate in various reactions of formation and polymerization; hydroxymethyl groups can involve substitution and esterification.
However, this substance is still stable under suitable conditions. At room temperature and pressure, without external factors such as catalysis, light, and high temperature, its molecular structure is difficult to spontaneously change drastically. Although the alkenyl group is active, factors such as the distribution of electron clouds in the molecule and steric hindrance can inhibit its reactivity and make it more stable.
The activity of hydroxymethyl groups is also restricted by naphthalene rings and ortho groups. The naphthalene ring has a conjugated system, and the electron cloud is delocalized, which can disperse the charge of hydroxymethyl and increase its stability. And the ortho-group has a steric resistance, or can hinder the reaction of hydroxymethyl, making it difficult to react without cause.
Usually stored, if it is protected from light, hot topic, strong oxidizing agent and reducing agent, etc., the physical properties of this compound can be stable for a long time, and it can be stored stably in the general environment, and it is not easy to change. Therefore, in general, the physical properties of 1% 2C3-diene-2-hydroxymethylnaphthalene are relatively stable.
What is the production process of 1,3-difluoro-2-nitrobenzene?
The production process of 1% 2C3-diene-2-carboxybenzoic acid is quite delicate and complicated. At the beginning, it is necessary to carefully select suitable raw materials, and the purity and quality of the raw materials have a great impact on the final product.
The first step is to use a specific organic compound as the starting material, and to carry out the chemical reaction under precisely controlled temperature and pressure conditions. This reaction must be carried out in a suitable reaction vessel, and during the reaction process, close attention should be paid to the fluctuation of temperature to ensure the smooth progress of the reaction, so as not to cause the growth of side reactions due to high or low temperature, which will damage the purity and yield of the product.
Next, after the product is initially formed, it needs to be separated and purified. This process often relies on a variety of separation techniques, such as distillation, extraction, and crystallization. During distillation, the target product is separated from the reaction mixture system according to the difference in boiling points of different substances; extraction uses the different solubility of substances in different solvents to achieve the purpose of separation; crystallization uses conditions such as temperature and solvent concentration to precipitate the product in the form of crystals, thereby improving the purity.
Furthermore, the purified product needs to be carefully tested and analyzed. By means of modern analytical instruments, such as mass spectrometry, nuclear magnetic resonance, etc., the structure and purity of the product are carefully checked to ensure that it meets the established Quality Standards.
Throughout the production process, the control of reaction conditions, the quality supervision of raw materials, and the application of separation and purification technologies all need to be rigorous and precise. A slight error may affect the quality and yield of the product. Only when all links are closely interlocked and properly operated can high-quality 1% 2C3-diene-2-carboxybenzoic acid be efficiently produced.
What are the precautions for storing and transporting 1,3-difluoro-2-nitrobenzene?
1% 2C3-diene-2-carbonylphenyl needs to pay attention to many key matters during storage and transportation.
The choice of the first storage environment. It is necessary to find a cool, dry and well-ventilated place, away from fire and heat sources. This is because of its certain chemical activity, high temperature or open flame is prone to danger, such as causing combustion or even explosion, which should not be underestimated. And humid environment or cause it to react with water, resulting in quality damage.
The second is the choice of storage container. When using a corrosion-resistant, well-sealed container. The lid is due to its special chemical properties, or reacts with certain materials. If the container is not resistant to corrosion, or causes damage to the container and leaks. The seal is not tight, or it reacts with air components, which affects its chemical stability.
In addition, the transportation process also needs to be extremely cautious. According to its dangerous characteristics, relevant transportation regulations and standards should be followed. The means of transportation must be safe and reliable, and there are perfect protection and emergency measures. When loading and unloading, the operator must handle it with care to prevent package damage. If the package is damaged and leaks, it is not only wasted, but also leaked or poses a threat to the environment and personal safety.
In addition, whether it is storage or transportation, it must be strictly marked. It should clearly indicate its chemical name, dangerous nature and emergency treatment methods. In this way, in the event of an emergency, the relevant personnel can quickly know the hazard and take appropriate measures.
In conclusion, 1% 2C3-diene-2-carbonyl benzene should not be ignored when storing and transporting, and must be treated with caution to ensure safety.