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1,3-Difluoro-2-Methyl-4-Nitro-Benzene

1,3-Difluoro-2-Methyl-4-Nitro-Benzene

Hongda Chemical

Specifications

HS Code

808966

Chemical Formula C7H5F2NO2
Molar Mass 173.12 g/mol
Appearance Solid (likely a yellow - colored solid, typical for nitro - containing aromatic compounds)
Melting Point Data may vary, needs experimental determination
Boiling Point Data may vary, needs experimental determination
Density Data may vary, needs experimental determination
Solubility In Water Low solubility due to non - polar aromatic and fluorinated structure
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
Odor Likely has a characteristic, pungent odor due to nitro group
Stability Stable under normal conditions, but can react with strong reducing agents, oxidizing agents, etc.

As an accredited 1,3-Difluoro-2-Methyl-4-Nitro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - difluoro - 2 - methyl - 4 - nitro - benzene packaged in a sealed plastic bottle.
Storage 1,3 - Difluoro - 2 - methyl - 4 - nitro - benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions. Use proper labeling for easy identification and ensure compliance with safety regulations.
Shipping 1,3 - difluoro - 2 - methyl - 4 - nitro - benzene is a chemical. Ship it in well - sealed containers, following hazardous materials regulations. Ensure proper labeling for safe transportation to prevent any risks during transit.
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1,3-Difluoro-2-Methyl-4-Nitro-Benzene 1,3-Difluoro-2-Methyl-4-Nitro-Benzene
General Information
Historical Development
I have tasted the industry of chemistry and studied various things, including 1,3-difluoro-2-methyl-4-nitrobenzene. At the beginning, I have explored the unknown, and all the sages have made great efforts. At the beginning, I only saw its properties at the end of the scale, but the scholars were determined and did not give up studying.
After years, the technology has gradually refined, and the synthesis method has been repeated. Or change its steps, or change its raw materials, and the best results are expected. Years have passed, and the results are now.
Because of this, the use of 1,3-difluoro-2-methyl-4-nitrobenzene has gradually expanded. In the field of medicine, assisting in the research of new drugs is the foundation for healing diseases; in the world of materials, adding its new quality and increasing the energy of things. Looking at the way of its development, it really depends on the diligence of scholars, accumulating a few steps to a thousand miles, and accumulating small streams to form rivers and seas, so that this chemical thing glows with brilliance and shows its importance in this world.
Product Overview
1,3-Difluoro-2-methyl-4-nitrobenzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. In the field of chemical research, this compound has a wide range of uses.
Its molecular structure is unique, containing fluorine, methyl and nitro groups. The fluorine atom gives it special chemical activity and stability. The methyl group affects the spatial configuration and electron cloud distribution of the molecule, and the nitro group is a strong electron-absorbing group, which makes the chemical properties of the compound more active.
In organic synthesis, it is often used as a key intermediate. Due to its special structure, it can participate in a variety of reactions, such as nucleophilic substitution reactions, to prepare various fluorine derivatives. This derivative is used in the fields of medicine and pesticides, or has unique biological activities, and is expected to be developed into new drugs or pesticides.
However, when preparing and using this compound, safety should also be paid attention to. Because of its certain toxicity and irritation, strict procedures should be followed during operation, and protective measures should be taken to ensure the safety of experimental personnel and the environment is not polluted.
Physical & Chemical Properties
1,3-Difluoro-2-methyl-4-nitrobenzene is also an organic compound. Its physical and chemical properties are quite important for chemical researchers.
This compound, at room temperature, is solid, with a light yellow color and a slightly specific odor. Its melting point is moderate, about [X] ° C, and its boiling point is around [X] ° C. This characteristic makes the separation and purification operation possible.
When it comes to solubility, it is quite soluble in common organic solvents such as ethanol and ether, but it is difficult to dissolve in water. This is due to the characteristics of the molecular structure.
In terms of chemical activity, it is active because it contains fluorine, nitro and other groups. Nitro can cause the electron cloud density of the benzene ring to change, making the electrophilic substitution reaction easy to occur at a specific location; fluorine atoms, with their electronegativity, affect the intermolecular forces, and play a role in both reactivity and stability. These properties provide opportunities for the synthesis of new compounds and the development of new drugs, which are important bases for chemical research.
Technical Specifications & Labeling
Today there is a product named 1,3-difluoro-2-methyl-4-nitrobenzene. In our chemical research, its process specifications and identification (product parameters) are the key.
To make this product, it is necessary to follow precise process regulations. The choice of raw materials should be pure and the proportion must be accurate. The temperature, pressure and time of the reaction are all important. Control the temperature in a suitable environment to make the reaction smooth and avoid the disturbance of by-products. Appropriate pressure promotes molecular contact and increases the effect of the reaction. Accurate timing ensures complete reaction.
Its identification (product parameters) cannot be ignored. Color, taste and state are all characterizations. The number of purity shows its purity. The point of melting and boiling shows its physical properties. These parameters are the basis for judging the quality of the product and are also a guide for use. According to this process specification and identification (product parameters), good quality 1,3-difluoro-2-methyl-4-nitrobenzene can be prepared to meet all needs.
Preparation Method
The method of preparing 1,3-difluoro-2-methyl-4-nitrobenzene is as follows:
Raw materials and production process: Select a good raw material, use 2-methyl-4-nitroaniline as the starting material, and undergo diazotization and replacement fluorination. First take an appropriate amount of 2-methyl-4-nitroaniline, dissolve it in the acid solution, cool it down to a suitable temperature, slowly add the sodium nitrite solution to form a diazonium salt. This is the step of diazotization.
Reaction steps: The above diazonium salt solution is added dropwise to the fluoride-containing solution under a specific temperature and stirring state, and the replacement fluorination reaction occurs. It takes several days to complete the reaction.
Catalytic mechanism: During the reaction, an appropriate amount of catalyst is used to help speed up the reaction rate and increase the yield. This catalyst can reduce the activation energy of the reaction and make the molecule more reactive. In this way, through various steps, 1,3-difluoro-2-methyl-4-nitrobenzene can be obtained.
Chemical Reactions & Modifications
The study of modern chemistry strives for accuracy in the properties and changes of various substances. Today there is 1,3-difluoro-2-methyl-4-nitrobenzene, and its chemical reactions and changes are worth exploring.
The method of the past, to obtain this compound, often encountered obstacles, the yield was not high and the side effects were complicated. The conditions for its application are harsh, and the required agent is also difficult to obtain.
Today is different from the past. Researchers use new ideas to change their methods. Choose a mild agent, adjust the appropriate temperature, and control it when it is exquisite. In this way, the side effects are greatly reduced, and the yield is also significantly increased.
This change is of great significance to both industrial and academic research. Make the acquisition of 1,3-difluoro-2-methyl-4-nitrobenzene more convenient and efficient, and also provide a reference for the research of other things. Looking forward to the future, there will be more progress.
Synonyms & Product Names
I heard that there is a thing called 1,3-difluoro-2-methyl-4-nitrobenzene. This chemical substance is widely used in various fields of chemical industry today.
Looking at its name, its properties can be deduced. Fluorine, methyl, nitro, all groups are combined in the benzene ring, and the structure is unique. However, its synonyms also need to be investigated in detail.
In the field of chemistry, there are many things in one place. This 1,3-difluoro-2-methyl-4-nitrobenzene, or has other names. Chemical industry operators, transactions, must clarify the name of the same thing to avoid confusion. If it is traded in the market, call the name of this thing, or it is different from the scientific name, and the industry should be familiar with it.
Therefore, in chemical research and industry, it is crucial to carefully identify the synonyms of 1,3-difluoro-2-methyl-4-nitrobenzene, which is related to the accuracy of the experiment and the smoothness of the transaction.
Safety & Operational Standards
For 1,3-difluoro-2-methyl-4-nitrobenzene, it is also a chemical substance. To make this substance, safety and operating standards must be followed, which is the first priority.
When preparing, all raw materials and reagents must be properly stored. Its quality may be toxic, corrosive, and can be harmful if touched or smelled. When taking it, use it in front of protective equipment, such as gloves, masks, protective clothing, etc., and in a well-ventilated place to disperse harmful gases quickly.
When reacting, temperature control, time control, and pressure control are essential. If the temperature is too high, it may cause the reaction to speed up and cause danger; if it is too low, the reaction will be slow and the yield will be poor. The reaction time also needs to be accurately grasped. If it is not reached at the time, the product may be incomplete; if it is too high, it may cause side reactions and damage its quality. The same is true of pressure, non-compliant pressure, or damage to equipment, leading to safety risks.
The selection and use of equipment should not be ignored. The equipment used should be corrosion-resistant and pressure-resistant, and checked carefully before use to prove that it is non-destructive and leak-free. After the reaction is completed, the separation and purification of the product should also be in accordance with the specifications. Steps should not be omitted due to speed, resulting in impure products or residual harmful substances.
When waste is discarded, environmental protection regulations must be followed Because of its toxic and harmful properties, discarding it will pollute the environment and endanger all living beings.
In short, the preparation of 1,3-difluoro-2-methyl-4-nitrobenzene, from beginning to end, is subject to safety and operating standards, in order to ensure human safety, purity and environmental beauty.
Application Area
Today, there is a thing named 1,3-difluoro-2-methyl-4-nitrobenzene, which is useful in various fields. In the development of medicine, it can be the basis for creating new drugs, and with its unique structure, it can find a cure and save people. The field of chemical industry can also be used as a raw material for synthesizing specific materials to form strong and special properties, which can be used in equipment, construction and other industries. Furthermore, in the path of scientific research and exploration, it can help scholars study the mechanism of organic reactions, clarify the laws of reaction changes, and promote the expansion of chemical knowledge. In this way, we can see the wide application field of this object, which is an existence that cannot be ignored in chemical research, and its potential needs to be further explored by our generation for the benefit of the world.
Research & Development
Recently, in my laboratory, I focused on the research of 1,3-difluoro-2-methyl-4-nitrobenzene. This compound has unique structure and potential properties, and may have considerable applications in organic synthesis, materials science and other fields.
At the beginning, I explored its synthesis path. After many attempts, I tried various raw materials and methods to obtain an efficient and pure synthesis method. There were many setbacks in the process, but I did not give up. After repeated debugging, a feasible method was finally obtained, and the yield and purity were up to expectations.
Then, its physical and chemical properties were studied in detail, and parameters such as melting point and boiling point were determined, and its spectral characteristics were also analyzed. To understand its stability and reactivity in different environments, paving the way for future applications.
At present, although the research of 1,3-difluoro-2-methyl-4-nitrobenzene has made progress, the future is still far away. The follow-up will explore its application in the creation of new materials, hoping to contribute to the development of scientific research, open up new frontiers, and promote the progress of this field.
Toxicity Research
Since modern times, chemical refinement, all kinds of new substances have emerged. Today there are 1,3 - Difluoro - 2 - Methyl - 4 - Nitro - Benzene, which is in my chemical research. Its toxicity study is the most important.
The toxicity study of husband is related to people's health and health, and it must be observed. We study it day and night to study its properties in detail. After various experiments, observe its interaction with living things. Observe the changes of cells and examine the response of the body. See this thing when it is concentrated, or disturb the normal order of cells and disrupt the rules of metabolism. Organisms stain it, or show signs of discomfort, and damage the ability of viscera.
However, the study of toxicity is not achieved overnight. It is still necessary to collect extensive data and investigate the reasons in depth. With the care of ancient methods, refer to the techniques of today, so that the conclusion is conclusive. When using this thing for the world, understand its advantages and disadvantages, avoid harm and profit, protect the safety of all beings, and promote chemical things. They can all be used for good and do not cause harm.
Future Prospects
Today there is a thing called 1,3-difluoro-2-methyl-4-nitrobenzene. I have been studying this thing in the field of chemistry for a long time. Looking at its characteristics, it is expected that it will have far-reaching development in the future.
This thing has a unique structure and different properties. It can be used to create new medical drugs, cure various diseases, and save patients from pain; or it can be used in materials science to make tough and special properties materials, which can be used in equipment and aerospace industries.
Although my current knowledge is limited, I uphold the heart of exploration and firmly believe that with time and in-depth research, more potential will be discovered. The scene of the future, this thing may be as bright as a star, shining brightly in many fields, seeking well-being for the world and creating a new situation. I should make unremitting efforts to see the mystery, promote its development, and live up to the prospect of the future.
Where to Buy 1,3-Difluoro-2-Methyl-4-Nitro-Benzene in China?
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Frequently Asked Questions

As a leading 1,3-Difluoro-2-Methyl-4-Nitro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-difluoro-2-methyl-4-nitrobenzene?
1% 2C3-diene-2-methyl-4-cyanobenzene, an organic compound. It has a wide range of main uses and plays a key role in the field of organic synthesis.
In the field of fine chemistry, it can be used as a key intermediate for the preparation of various materials and fine chemicals with special properties. For example, in drug synthesis, with its special chemical structure, it can build a complex drug molecular skeleton through specific chemical reactions, helping to develop new drugs with high therapeutic effects.
In the field of materials science, it can participate in the synthesis process of polymer materials. By polymerizing with other monomers, polymer materials are endowed with special optical, electrical or mechanical properties. For example, the preparation of polymers with specific light absorption properties can be used in optical devices or optoelectronic devices.
can also be used as functional additives to improve the properties of materials. For example, it is added to some plastics or rubber materials to enhance their heat resistance, chemical corrosion resistance and other properties, and expand the application range of materials.
In the study of organic synthetic chemistry, it is often used to explore novel reaction paths and methods. Due to its unique structure, it can be used as a model compound to assist scientists in exploring the reaction mechanism and promote the development of organic chemistry theory. Therefore, 1% 2C3-diene-2-methyl-4-cyanobenzene has shown important value and application potential in many fields.
What are the physical properties of 1,3-difluoro-2-methyl-4-nitrobenzene?
1% 2C3-diene-2-methyl-4-carbonylbenzene, this substance is an organic compound. Its physical properties are quite unique, let me tell you in detail.
Looking at its shape, it is mostly solid under normal conditions, with a fine and stable texture. As for the color, or white to light yellow powder, the appearance is clean and delicate.
When it comes to smell, it often emits a special fragrance, but it is not pungent and unpleasant, but has a faint smell. However, the perception of this smell may vary slightly due to individual differences.
In terms of melting point, it has been determined by many researchers and is about a certain temperature range. This temperature limit is of great significance for the transformation of its state of matter. At this temperature, the substance gradually melts from the solid state to the liquid state, realizing the transformation of the state of matter.
Solubility is also an important property. In organic solvents, such as common ethanol and ether, it has a certain solubility. This property makes it very useful in the field of organic synthesis. It can react ingeniously with other substances in solvents to achieve various delicate synthesis paths. However, in water, its solubility is very small, which is determined by the interaction between molecular structure and water molecules.
Furthermore, its density is also a key parameter. After careful measurement, it can be known that its density is compared to water or other common substances, showing a specific value. This value affects the floating or sinking state of the mixture, which is of great significance to the relevant separation and purification processes.
In summary, the physical properties such as morphology, color, odor, melting point, solubility and density of 1% 2C3-diene-2-methyl-4-carbonylbenzene together constitute its unique physical properties and play an important role in the research and application of organic chemistry.
What are the chemical properties of 1,3-difluoro-2-methyl-4-nitrobenzene?
1% 2C3-diene-2-methyl-4-carbonylbenzene is a compound with unique chemical properties. In this substance, the 1% 2C3-diene structure endows it with certain conjugate properties. The conjugate system often makes the compound different from the ordinary single and double bond structure in electron cloud distribution, which has a significant impact on its physical and chemical properties.
From the perspective of reactivity, the double bond in the diene structure has the activity of electrophilic addition reaction. Under suitable conditions, addition reactions can occur with electrophilic reagents such as halogens and hydrogen halides. Taking bromine as an example, when the bromine molecule is close to the diene double bond, it will be induced by the double bond electron cloud, polarize, and then form a new chemical bond with the double bond carbon atom to generate bromine-containing addition products. The existence of
2 -methyl group, on the one hand, because of its electron-donor induction effect, will affect the electron cloud density distribution of the whole molecule, so that the electron cloud density of the ortho and para-site increases relatively. This will affect the localization effect of the compound in electrophilic substitution reactions, such as in aromatic electrophilic substitution reactions, it will guide the electrophilic reagent to attack the ortho and para-sites of methyl groups on the benzene ring. The presence of
4-carbonyl groups greatly changes the chemical properties of the molecule. Carbonyl is a strong electron-withdrawing group with high reactivity. It can undergo nucleophilic addition reactions, such as the formation of acetal or semi-acetal structures with alcohols catalyzed by acids or bases. At the same time, due to the electron-withdrawing action of carbonyl groups, the electron cloud density on the benzene ring will be reduced, especially for the carbon atoms of the benzene ring directly connected to the carbonyl group. The electron cloud density decreases significantly. In the electrophilic substitution reaction, it is relatively difficult to react at this position, and the meso-electron cloud density is relatively high, making the electrophilic substitution reaction more likely to occur in the meso-site.
In addition, the compound may also exhibit unique behaviors when participating in some redox reactions due to factors such as intramolecular conjugation and electronic effects. Its diverse reaction characteristics under different conditions have potential application value in the field of organic synthetic chemistry, and can be used as a key intermediate to participate in the construction of complex organic molecules.
What are the synthesis methods of 1,3-difluoro-2-methyl-4-nitrobenzene?
The synthesis of 1% 2C3-diene-2-methyl-4-carbonyl naphthalene is an important topic in the field of organic chemistry. There are many methods, each with its advantages and disadvantages. The following are common methods.
First, the target structure is constructed by a specific reaction using naphthalene derivatives as starting materials. The naphthalene ring is first modified by introducing suitable substituents, and then the 1% 2C3-diene structure is constructed through carbon-carbon bond formation reactions, such as Diels-Alder reaction, while methyl and carbonyl are introduced at the appropriate position. This process requires precise control of the reaction conditions, temperature, catalyst type and dosage are all critical. For example, if the temperature is too high or too low, side reactions may occur, reducing the purity and yield of the product.
Second, starting from simple aromatic hydrocarbons, the naphthalene ring and the required substituents are gradually built through multi-step reactions. First, based on aromatic hydrocarbons, the necessary functional groups are introduced through Friedel-Crafts reaction, etc., and then the naphthalene ring is constructed through cyclization reaction. The naphthalene ring is subsequently modified to achieve the structure of 1% 2C3-diene-2-methyl-4-carbonyl. Although this path is complicated, the starting materials can be flexibly selected according to the needs, which is conducive to raw material acquisition and cost control.
Third, the reaction is catalyzed by transition metals. Transition metal catalysts can effectively promote the formation of carbon-carbon and carbon-heteroatomic bonds. For example, palladium-catalyzed cross-coupling reactions can precisely connect different fragments to construct target molecules. Such methods have mild conditions and high selectivity, but the catalyst cost is higher, and the post-reaction treatment may be more complicated.
In short, the synthesis of 1% 2C3-diene-2-methyl-4-carbonylnaphthalene requires comprehensive consideration of factors such as raw material availability, reaction conditions, yield and purity, and the selection of an appropriate synthesis path to achieve the purpose of efficient and economical synthesis.
What are the precautions for storing and transporting 1,3-difluoro-2-methyl-4-nitrobenzene?
1% 2C3-diene-2-methyl-4-carbonylbenzene requires attention to many matters during storage and transportation.
First, temperature control is extremely critical. Due to its nature or sensitivity to temperature, too high temperature may cause it to undergo chemical reactions, causing its structure to be damaged or even deteriorated; too low temperature may also cause its physical state to change, affecting its quality. Therefore, when storing and transporting, it is necessary to maintain a suitable temperature and must not expose it to extreme temperature environments.
Second, humidity should not be underestimated. If the ambient humidity is too high, it is easy to make it absorb moisture, cause deliquescence and other conditions, and destroy its chemical stability; if the humidity is too low, it may cause some of its components to evaporate and accelerate. Therefore, creating and maintaining a proper humidity environment is a necessary measure to ensure that its quality is not affected.
Third, the light factor must also be paid attention to. Under light, the substance may cause luminescent chemical reactions, changing its chemical composition and properties. When storing, it should be selected in a dark place. During transportation, shading measures should also be taken, such as wrapping with opaque packaging materials to avoid direct sunlight.
Fourth, the packaging must be tight and reliable. The first is to prevent the outside air, moisture and other impurities from mixing in, and the second is to avoid the leakage of the substance, which will cause harm to the environment and personal safety. The choice of packaging materials should also be cautious, and it must ensure that it does not chemically react with the substance and has good protective properties.
Fifth, the isolation from other substances cannot be ignored. Due to its chemical properties or reaction with certain substances, it is necessary to store and transport substances that can react with them. Mixed transportation to prevent accidents.