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1,3-Difluoro-2-Isothiocyanatobenzene

1,3-Difluoro-2-Isothiocyanatobenzene

Hongda Chemical

    Specifications

    HS Code

    303257

    Chemical Formula C7H3F2NS
    Molecular Weight 171.17
    Appearance Typically a liquid
    Boiling Point Specific data needed from experimental results
    Melting Point Specific data needed from experimental results
    Density Specific data needed from experimental results
    Solubility Solubility characteristics in common solvents like organic solvents need experimental determination
    Flash Point Specific data needed from experimental results
    Vapor Pressure Specific data needed from experimental results
    Pungency Likely pungent due to isothiocyanate group

    As an accredited 1,3-Difluoro-2-Isothiocyanatobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1,3 - difluoro - 2 - isothiocyanatobenzene packaged in a sealed glass bottle.
    Storage 1,3 - difluoro - 2 - isothiocyanatobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances like strong oxidizing agents, acids, and bases. Store in a tightly - sealed container to prevent leakage and exposure to air, which could lead to decomposition or reaction.
    Shipping 1,3 - difluoro - 2 - isothiocyanatobenzene is a chemical. Shipping should be in accordance with hazardous chemical regulations. Use properly labeled, leak - proof containers and ensure transportation by carriers authorized for such chemicals.
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    1,3-Difluoro-2-Isothiocyanatobenzene 1,3-Difluoro-2-Isothiocyanatobenzene
    General Information
    Historical Development
    Those who have heard the goodness of ancient times are chemical workers, in the study of materials, with great care. 1,3 - Difluoro - 2 - Isothiocyanatobenzene This thing, its beginning is also, or hidden in the dark, not known to everyone. However, those who are chemical engineers study the material properties, and study it over the years. At the beginning, I explored the method of synthesis, and tried many times, encountering all kinds of difficulties, and never slack. Gradually obtained its method, able to make this thing, although the quantity is still small, it is already the beginning. Later scholars, carry on their ambitions, follow their industry, and strive for excellence in the art of synthesis. Improve the process, increase the output, and make this thing gradually used in various fields. From this point of view, the development of 1,3 - Difluoro - 2 - Isothiocyanatobenzene really depends on the research of all the sages.
    Product Overview
    1,3-Difluoro-2-isothiocyanate benzene is also an organic compound. It has unique properties, with difluorine atoms and isothiocyanate radical groups, exquisite structure, and has attracted much attention in the field of organic synthesis.
    This compound may be light in color or different in taste. Its physical properties such as melting point and solubility are all related to the bond energy and group interaction in the molecule. Its chemical activity is derived from the activity of isothiocyanate radical groups. It can react with many nucleophiles to generate new compounds. It has potential for application in fields such as medicine, pesticide research and development, and materials science.
    The synthesis method requires fine operation and control of reaction conditions to achieve the goal of high efficiency and high purity. In-depth exploration of it may open up new frontiers for chemical research, and it is also expected to shine on the practical road and contribute to the progress of science and technology.
    Physical & Chemical Properties
    The phenyl 1,3-difluoro-2-isothiocyanate has specific physical and chemical properties. Its shape may be colorless to light yellow liquid with a pungent smell. Looking at its physical properties, the boiling point is suitable for a specific temperature. At this temperature, the substance gradually converts from liquid to gaseous state, which is the key node of its gasification. And its density is also fixed, reflecting its mass characteristics per unit volume.
    In terms of its chemical properties, it is quite active due to its isothiocyanate group. It can react with many nucleophilic reagents such as alcohols and amines. When it encounters alcohols, it may form carbamate derivatives; when it interacts with amines, it is easy to form thioureas. Due to the distribution of carbon-nitrogen double bonds and electron clouds of sulfur atoms in the isothiocyanate group, it is vulnerable to attack by nucleophiles. Such various physical and chemical properties provide opportunities for the preparation of characteristic compounds in the field of organic synthesis, and also add a lot of interest and exploration space to chemical research.
    Technical Specifications & Labeling
    Technical specifications and labels for phenyl 1,3-difluoro-2-isothiocyanate (product parameters)
    Fu 1,3-difluoro-2-isothiocyanate, its technical specifications, the first purity. When measured by a precise method, the pure product should reach more than 99%, and the impurities should be fine. The color is transparent, no variegated dye, and the appearance is clear.
    As for the label, the name of the product must be stated "1,3-difluoro-2-isothiocyanate phenyl ester", and the chemical formula should be noted to make it clear at a glance. Repeat the label with the date of production and the batch number for traceability. Its packaging should also be carefully guarded to prevent it from leaking, and accompanied by warnings, saying that it is irritating to a certain extent, so that the operator knows what to avoid and avoid to ensure safety. In this way, the technical specifications and logos are ready, which is the model of good products.
    Preparation Method
    To prepare 1,3-difluoro-2-isothiocyanate benzene, the method is as follows:
    Prepare raw materials, select pure fluorobenzene, supplemented by thiocyanate and other materials. In a clean vessel, put it in sequence at a suitable temperature. First react the fluorobenzene with a specific reagent, control the temperature at [X] ° C, stir slowly, and wait for it to finish, to obtain the intermediate product.
    times, move this intermediate to another vessel, add thiocyanate, adjust the temperature to [Y] ° C, continue stirring, and over time, the reaction will gradually complete. Here, temperature control and stirring speed are both heavy, which are related to the purity and quantity of the product. After
    , it is separated by a delicate method to remove its impurities and obtain pure 1,3-difluoro-2-isothiocyanate benzene. The whole process must abide by the procedures, observe the changes, and adjust it in time to get the best product.
    Chemical Reactions & Modifications
    1,3-Difluoro-2-isothiocyanate benzene is an organic compound. In the field of chemistry, its reaction and modification are of great importance to researchers.
    Looking at its reaction, when it encounters nucleophiles, it often causes nucleophilic addition. If it encounters alcohols, it can form a new thiocarbamate. This reaction varies in speed and rate according to the properties, temperature and solvent of the reagent.
    As for modification, for better properties, its structure is often changed. Or add a group to the benzene ring to adjust its electron cloud density and change the reaction activity. Or the substituent of isothiocyanate can change its chemical activity and selectivity.
    In order to obtain better properties and reactions, researchers often explore new ways. Or seek efficient stimulants, or seek suitable reaction environments. After various explorations, it is hoped that this compound will be widely used in medicine, materials and other fields to develop its capabilities.
    Synonyms & Product Names
    Today there is a thing called 1,3-Difluoro-2-Isothiocyanatobenzene. Its synonymous name is also the subject of research. This chemical thing has its uses in various fields. Or it can be called a specific variant of phenyl difluoroisothiocyanate, which is a synonymous name. As for the name of the product, it may vary according to the manufacturer, the use, etc.
    The name of the chemical substance has many synonyms. If you want to understand its nature and know its use, you must carefully investigate its synonymous name and the name of the product. 1,3-Difluoro-2-phenyl isothiocyanate, its synonymous name can help researchers in various literature to understand the truth; the name of the product is related to its practical use and market status. In the way of my chemical research, detailed study of this equivalence and the name of the product, in order to have a complete understanding of 1,3-difluoro-2-isothiocyanate, in order to facilitate the progress of research and wide application.
    Safety & Operational Standards
    Safety and operating specifications for 1,3-difluoro-2-isothiocyanate benzene
    1,3-difluoro-2-isothiocyanate benzene, this chemical substance must be strictly followed in the experiment and production of safety and operating regulations to ensure that everything goes smoothly and personnel are safe.
    In terms of safety, the first protection. This material is toxic and irritating, and protective equipment must be adapted when it comes into contact. Experimenters should wear tight protective gloves, and the material should be selected to effectively block its erosion to prevent skin contact, allergies or burns. Eye protection is also indispensable. The goggles must be able to protect in all directions to block their splashing into the eyes and avoid damage to the vision. The mouth and nose must also be protected with suitable masks to avoid the inhalation of volatile gases and damage to the respiratory tract.
    In terms of operating specifications, environmental selection is crucial. The operation should be carried out in a well-ventilated place. It is best to be a laboratory or workshop with a perfect ventilation system, which can quickly discharge volatile harmful gases and reduce the concentration in the air. When taking it, the action must be precise and careful. Measure it with clean and dry special equipment, and measure it accurately according to the needs of the experiment or production to avoid waste and excessive risk. And during the transfer process, beware of drip. If there is any drip, clean it immediately to prevent spread.
    When storing, also pay attention to it. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Due to high temperature or open flame or its reaction, it will cause safety accidents. And it should be packed in a sealed container to prevent leakage and qualitative change caused by contact with air.
    After the experiment or production is completed, properly dispose of the residue. Do not dump at will. According to relevant regulations, collect it by classification and hand it over to professional institutions for handling to ensure that the environment is not polluted.
    In short, in the entire life cycle of 1,3-difluoro-2-isothiocyanate benzene, safety and operating norms must be kept in mind at all times to avoid danger and promote the orderly progress of scientific research and production.
    Application Area
    1,3-Difluoro-2-phenyl isothiocyanate, this chemical substance, its application field is very critical. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize special drugs to treat various diseases. In the field of materials science, it can react with other substances to obtain new materials with special properties, such as high-strength and corrosion-resistant polymers, which are widely used in industrial equipment, aerospace and other fields. In agricultural chemistry, it may participate in the synthesis of high-efficiency and low-toxicity pesticides to protect crops from pests and ensure a bumper harvest. It has significant functions in many fields and is an indispensable part of scientific research and industrial development. Like a star, it shines brightly in the scientific firmament, attracting researchers to explore and expand the vast world of its application.
    Research & Development
    Today, there is a thing named 1,3-difluoro-2-isothiocyanate phenyl ester, which is quite crucial in the field of chemical research in China. Yu et al. tried his best to explore its properties.
    At first, analyzing its structure, it was clear that the chemical bonds were connected, the atomic arrangement was known, and the molecular structure was known. Then study its reaction, explore its change with the phase and phase of various substances, and observe its transformation under different conditions. Or the rise and fall of temperature, or the increase and decrease of agents, are all studied in detail.
    After months of research, its properties and reaction mechanism have gradually gained. This gain not only enhances our knowledge, but also paves the way for its application. In the future, we can use this research to develop its applications, whether in medicine or in materials, to contribute to the progress of the world, and to promote the long-term development of this chemical material for the benefit of everyone.
    Toxicity Research
    Toxicity Study of Phenyl 1,3-Difluoro-2-isothiocyanate
    Phenyl 1,3-difluoro-2-isothiocyanate is a chemical substance. In the field of chemical research, the discussion of its toxicity is quite important.
    The toxicity of this substance has been gradually clarified after many studies. It may affect various systems of the organism. Observe its effect on cells, or it may cause changes in cell structure and function. In animal experiments, observe that after ingestion, the body may present adverse reactions, such as signs of organ damage.
    The depth of toxicity also varies depending on the dose and exposure route. A small amount of short-term exposure, or only minor discomfort; if a large amount of long-term exposure, the harm increases sharply.
    We chemical researchers should be cautious. Where it is produced and used, strict protection measures must be set to avoid harm to the human body and the environment. In this way, the safety of scientific research and production can be guaranteed, and the ecological tranquility can be protected.
    Future Prospects
    The future perspective concerns the phenyl 1,3-difluoro-2-isothiocyanate. Our generation has done our best in the research of these things. Although what we have obtained at the moment, we can see the leopard in the pipe, but what we want is the whole of it.
    Look at this phenyl 1,3-difluoro-2-isothiocyanate, which is unique in nature and has potential and great uses in many fields. The way of medicine may be able to create new ways and add powerful tools for treating diseases; the field of materials may be able to use it to give new energy and make the material more superior.
    We are determined to study, and we hope that in the near future, we can maximize its potential and explore its endless potential. At that time, phenyl 1,3-difluoro-2-isothiocyanate will be like a pearl in the dust, shining in the world, used by the world, and beneficial to all people. This is the future ambition of our researchers and their unremitting pursuit.
    Where to Buy 1,3-Difluoro-2-Isothiocyanatobenzene in China?
    As a trusted 1,3-Difluoro-2-Isothiocyanatobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,3-Difluoro-2-Isothiocyanatobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of phenyl 1,3-difluoro-2-isothiocyanate
    1% 2C3-diene-2-isothiocyanate benzyl ester, which has important applications in chemical industry, medicine, agriculture and other fields.
    In the chemical industry, it is often used as a key intermediate in organic synthesis. With its special chemical structure, it can participate in the construction of many complex organic compounds. For example, in the synthesis of new polymer materials, this structural unit can be introduced through a specific chemical reaction to endow the material with special optical, electrical or mechanical properties, laying the foundation for the development of high-performance and multi-functional new materials.
    In the field of medicine, studies have found that it has certain biological activity. Some studies have shown that it has inhibitory effects on the growth and proliferation of some cancer cells, and may become a potential lead compound for the development of anti-cancer drugs. Scientists hope to develop new anti-cancer drugs with better efficacy and less side effects by modifying and optimizing their structures. At the same time, there are also explorations in antibacterial and antiviral, or have inhibitory activity on specific bacteria, providing ideas for the development of new anti-infective drugs.
    In the agricultural field, 1% 2C3-diene-2-isothiocyanate can be used as a natural pesticide. Because of its repellent or inhibitory effect on some pests and pathogens, it can be used in green agricultural production, reduce the use of chemical pesticides, reduce environmental pollution, and help to achieve sustainable agricultural development. For example, in the process of vegetable and fruit cultivation, the rational application of preparations containing this ingredient can effectively prevent and control pests and diseases, and ensure the yield and quality of crops.
    What are the physical properties of phenyl 1,3-difluoro-2-isothiocyanate?
    1% 2C3-diene-2-isopropylbutyrate naphthyl ester has unique physical properties. Its properties are usually colorless to light yellow oily liquids, which exist stably at room temperature and pressure.
    Looking at its boiling point, it is about a certain temperature range. This characteristic makes it possible to realize the transformation of gas and liquid under specific conditions, which is very critical for separation and purification processes. Its melting point is also fixed, reflecting the critical temperature of the solid-liquid transition of a substance, which helps to understand its physical form at low temperatures.
    Furthermore, density is its important property. The appropriate density makes it unique in a specific medium. It either floats above or sinks below, which is of great significance in the research and application of mixed systems.
    In terms of solubility, it is soluble in some organic solvents, such as ethanol, ether, etc., but insoluble in water. This property determines its ability to disperse and react in different solvent environments, and affects its performance in various chemical processes and industrial applications.
    In addition, its refractive index also has characteristic value. Refractive index can be used to identify purity and concentration. When light passes through the substance, it can judge the change of its composition and content according to the degree of refraction, which is significant in the field of quality control and analysis and detection.
    Its volatility is weak, and it is not easy to evaporate rapidly in the air, which brings convenience to storage and use, does not require special harsh sealing conditions, and can maintain relatively stable content and performance, which is very important in actual production and application.
    Is the chemical property of phenyl 1,3-difluoro-2-isothiocyanate stable?
    1% 2C3-diene-2-isopentenoic acid geranyl ester, this is an organic compound. Whether its chemical properties are stable needs to be analyzed in detail.
    In terms of molecular structure, the compound contains functional groups such as carbon-carbon double bonds and ester groups. Carbon-carbon double bonds have high reactivity and are prone to addition reactions, such as addition to electrophilic reagents such as halogens and hydrogen halides, and may also participate in oxidation reactions. Under appropriate conditions, they are oxidized to alters, ketones or carboxylic acids. And ester groups are not stable and can be hydrolyzed under acidic or alkaline conditions. In acidic media, hydrolysis generates corresponding acids and alcohols; under alkaline conditions, hydrolysis is more thorough, generating carboxylic salts and alcohols, which is a saponification reaction.
    However, if it is placed in a specific environment without the above-mentioned reagents that can initiate the reaction, and the temperature, light and other conditions are suitable, it can also remain relatively stable for a certain period of time. For example, in a low temperature, dark and dry inert gas protective atmosphere, the possibility of molecular structure changes will be reduced.
    Overall, 1% 2C3-diene-2-isovalerate geranyl ester is not chemically stable due to its active functional groups, but its relative stability can be maintained to a certain extent by controlling external conditions.
    What are the synthesis methods of phenyl 1,3-difluoro-2-isothiocyanate?
    1% 2C3-diene-2-benzyl isothiocyanate, which is a very important compound in the field of organic synthesis. Its synthesis methods are diverse, and it is described in ancient Chinese.
    First, the corresponding alcohol can be started. First, take a suitable alcohol, halogenate it, and treat it with a halogenating agent, so that the hydroxyl group of the alcohol is replaced by a halogen to obtain a halogenated hydrocarbon. This halogenated hydrocarbon is an active halogen atom, which can be a key check point for subsequent reactions. Subsequently, the halogenated hydrocarbon and thiocyanate are co-placed in a suitable solvent, heated and stirred, and a nucleophilic substitution reaction occurs. The thiocyanate ion attacks the carbon atom of the halogenated hydrocarbon, and the halogen ion leaves to obtain a thiocyanyl-containing compound. Finally, through a specific dehydration or elimination reaction, a double bond is introduced to construct a 1% 2C3-diene structure, and the final result is 1% 2C3-diene-2-benzyl isothiocyanate.
    Second, an aldehyde or ketone can also be used as a raw material. First, the aldehyde or ketone undergoes a condensation reaction with a specific organic reagent to increase the carbon chain and introduce a specific functional group. For example, it reacts with a reagent such as an enol silica ether under catalytic conditions to form an intermediate with an enol structure. This intermediate is then reacted with thiocyanic acid-related reagents, such as thiocyanate under mild oxidation conditions, to transform the enol structure into an allyl structure containing thiocyanyl groups. Subsequent rearrangement or modification reactions are appropriate to optimize the double bond position and the structure of the benzyl ester moiety, so as to achieve the synthesis of 1% 2C3-diene-2-benzyl isothiocyanate.
    Third, the conversion of aromatic derivatives is used. First select the aromatic hydrocarbon containing benzyl structure, and introduce appropriate substituents at the benzyl position through Friedel-Crafts reaction, which lays the foundation for the subsequent introduction of thiocyanate and diene structures. Subsequently, through multi-step reactions, such as oxidation, nucleophilic substitution, elimination, etc., the structure of each part of the target compound is gradually constructed, and finally 1% 2C3-diene-2-benzyl isothiocyanate is synthesized. During the synthesis process, attention should be paid to the precise control of the reaction conditions, such as temperature, pH, reaction time, etc., so that the reaction can proceed in the expected direction and obtain the ideal yield and purity.
    What are the precautions for the storage and transportation of 1,3-difluoro-2-isothiocyanate phenyl ester?
    1% 2C3-diene-2-isothiocyanate phenyl ester is toxic and active. During storage and transportation, the following things must be paid attention to:
    First, the storage environment is crucial. It needs to be placed in a cool, dry and well-ventilated place. It must not be near fire or heat sources to prevent it from volatilizing or triggering chemical reactions due to excessive temperature. Because of its flammability, the storage site must strictly prohibit fireworks and be equipped with suitable fire protection facilities. At the same time, it should be stored separately from oxidants, acids, alkalis and other substances. Due to the active chemical properties of the substance, it is easy to react with the above substances, thus endangering safety.
    Second, the packaging must be tight. Suitable packaging materials need to be selected to ensure that there is no risk of leakage. Usually packaged in sealed glass bottles or metal drums, warning signs should be clearly marked on the outside of the package, such as "toxic" and "flammable", so that the contact can be seen at a glance and handled with caution.
    Third, the transportation process should not be underestimated. The transportation vehicle should have good ventilation conditions, and measures such as sun protection, rain protection, and high temperature protection should be taken. The transportation personnel must be professionally trained and familiar with the characteristics of the item and emergency treatment methods. During transportation, the condition of the goods should be checked regularly. If the packaging is found to be damaged or there are signs of leakage, corresponding measures should be taken immediately, such as transferring to a safe place and plugging the leakage.
    Fourth, the storage and transportation places should be equipped with complete emergency treatment equipment and protective equipment, such as gas masks, protective gloves, eye washers, etc. In the event of a leak or other accident, personnel can take emergency treatment in time to reduce the degree of harm.