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1,3-Difluoro-2-Bromobenzene

1,3-Difluoro-2-Bromobenzene

Hongda Chemical

Specifications

HS Code

167073

Chemical Formula C6H3BrF2
Molar Mass 193.009 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 157 - 159 °C
Melting Point N/A
Density 1.724 g/cm³
Solubility In Water Insoluble
Flash Point 53 °C
Refractive Index 1.503
Purity Typically high - purity in commercial products

As an accredited 1,3-Difluoro-2-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 mL glass bottle with screw - cap, containing 50 g of 1,3 - difluoro - 2 - bromobenzene.
Storage 1,3 - difluoro - 2 - bromobenzene should be stored in a cool, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly - sealed container, preferably made of corrosion - resistant materials like glass. This helps prevent leakage and degradation, ensuring its stability and safe storage.
Shipping 1,3 - difluoro - 2 - bromobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transportation regulations, ensuring proper handling to prevent leakage and maintain safety during transit.
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1,3-Difluoro-2-Bromobenzene 1,3-Difluoro-2-Bromobenzene
General Information
Historical Development
1,3-Difluoro-2-bromobenzene is also a chemical product. Tracing back to its origin, people initially explored the field of chemistry and studied halogenated aromatic hydrocarbons. At that time, many talents were dedicated to the creation of new compounds.
In the early days, only crude methods were obtained, and it was very difficult to make this product, and the yield was also low. After countless craftsmen worked hard to improve the process. Some wise people analyzed the reaction mechanism in depth, optimized the reaction conditions, and gradually increased the yield. There are also good thinkers in the selection of raw materials and the use of catalysts, which made the synthesis process smoother.
After years of delay, the technology is becoming more and more mature. From the prototype of the laboratory to the large-scale preparation, 1,3-difluoro-2-bromobenzene has emerged in various fields of chemical industry, and its use has become increasingly widespread. It is a brilliant pearl in the development of chemistry.
Product Overview
1,3-Difluoro-2-bromobenzene is an important raw material for organic synthesis. Its color is clear and taste is different, and it has unique chemical properties. In this compound, the position of fluorine and bromine atoms is delicate, giving it special reactivity.
In the field of synthesis, 1,3-difluoro-2-bromobenzene has a wide range of uses. It can be used as a key intermediate and participates in the construction of many complex organic molecules. With its halogen activity, it can react with many reagents such as nucleophilic substitution and coupling, opening up a path for the creation of new compounds.
The preparation method often requires exquisite craftsmanship. Or through a specific halogenation reaction, the reaction conditions can be precisely adjusted to achieve the ideal yield and purity. Its stability is acceptable under moderate conditions, but it will also change in extreme situations such as high temperature and strong acid and alkali.
In the chemical industry, the demand for 1,3-difluoro-2-bromobenzene is growing. Due to the fact that many emerging materials, drug research and development and other fields rely on its unique properties to help achieve innovative breakthroughs.
Physical & Chemical Properties
1,3-Difluoro-2-bromobenzene is also an organic compound. Its physical and chemical properties are worth exploring. Looking at its physical properties, at room temperature, it is a colorless to pale yellow liquid with a special odor. Its boiling point is moderate, about a certain temperature range. This property is related to its separation and purification. Its density is fixed, and it is related to its floating and sinking in different media.
In terms of its chemical properties, the presence of fluorine and bromine atoms gives it active reactivity. The structure of the benzene ring allows it to participate in the typical reactions of many aromatic compounds. The electronegativity of fluorine atom affects the distribution of electron cloud, changes the density of its ortho-site and para-site electron cloud, and then affects the activity and check point of electrophilic substitution reaction. Bromine atom is also an important reaction check point, which can occur nucleophilic substitution and other reactions, and has broad application prospects in the field of organic synthesis.
Technical Specifications & Labeling
1,3-Difluoro-2-bromobenzene is an important raw material for organic synthesis. Its process specifications and identification (product parameters) are related to the advantages and disadvantages of production and the accuracy of application.
The preparation of this product should follow a rigorous method. In the reactor, the temperature is controlled at an appropriate degree, and the specific reagent is used in an orderly manner according to the precise ratio. When reacting, closely observe its changes, keep its rate, and ensure the smooth reaction.
As for the label, its purity must reach the high standard, and the content of impurities is minimal. Remember its physicochemical properties, melting point, density, color and taste, etc., all of which are well prepared. On the packaging, a warning is marked to indicate the chemical risk and prevent problems before they occur. Only in this way can 1,3-difluoro-2-bromobenzene be used safely and efficiently in the chemical field.
Preparation Method
To prepare 1,3-difluoro-2-bromobenzene, the raw materials, production process, reaction steps and catalytic mechanism are the key. First, take o-bromoaniline as the initial raw material, and then react with diazotization to prepare diazonium salt with sodium nitrite and hydrochloric acid. This step needs to be controlled at low temperature to prevent the decomposition of diazonium salts.
Then, the resulting diazonium salt reacts with fluoroboronic acid to form fluoroboronic acid diazonium salt precipitation, which is separated and dried. Then the dried fluoroboronic acid diazonium salt is heated and decomposed to obtain 1,3-difluoro-2-bromobenzene. In this decomposition process, a suitable catalyst needs to be selected to promote the efficient progress of the reaction, and attention should be paid to the control of the reaction conditions to ensure the purity and yield of the product. The whole preparation process, each step is closely linked, and the operation needs to be fine and careful to achieve the expected preparation effect.
Chemical Reactions & Modifications
There is now a substance called 1,3-difluoro-2-bromobenzene. In the field of chemistry, it is the priority of our chemists to explore its reaction and modification.
Looking at its reaction, this compound can interact with various reagents under specific conditions. In case of nucleophilic reagents, its bromine atoms are active and easily replaced by nucleophilic groups, resulting in nucleophilic substitution reactions. This reaction can lay the foundation for the construction of new chemical structures.
Regarding its modification, in order to optimize its properties, different functional groups can be introduced. Or adjust its spatial structure by chemical means to change the physical and chemical properties of the compound. If you want to improve its solubility, you can try to access hydrophilic groups; if you want to enhance its stability, you can consider building more stable chemical bonds.
After careful research and exploration, it may be possible to explore the potential uses of 1,3-difluoro-2-bromobenzene in new materials, drug development and other fields, contributing to the development of chemistry.
Synonyms & Product Names
1,3-Difluoro-2-bromobenzene is also a chemical substance. In the field of my chemical research, the study of this substance's nickname and trade name is quite important.
Looking at various ancient books, there are many different names. Or because of its structural characteristics, there are those who combine positions and element names, such as o-difluorobromobenzene. This is named according to the position and type of substituents on its benzene ring, in order to clarify its spatial structure.
As for the trade name, due to the needs of the city and the industry, the orders of each merchant are also different. There are those who are simple and easy to remember, so that people in the industry can know their nature when they hear it; there are also those who want to show their unique quality and name it with a good name, hoping to win a place in the market.
We study this thing in detail to study its synonym and trade name. First, it helps to communicate accurately and convey information in the industry without error. Second, we can observe the dynamics of the market and know the development of the industry. Although the names are different but the quality is the same, the change of names is also the slight manifestation of the rise and fall of the industry.
Safety & Operational Standards
For 1,3-difluoro-2-bromobenzene, chemical products are also. In the field of our chemical researchers, its safety and operation standards are of paramount importance, and it is related to the success of everything and personal safety.
Fu 1,3-difluoro-2-bromobenzene has special properties. It is an organic halide, at room temperature, or in a liquid state, with a specific odor. Because of its fluorine and bromine atoms, it has special chemical activity and encounters with other substances, or reacts.
Safety is the first priority. Those who handle this substance should wear protective gloves and goggles in front of suitable protective clothing. This is to prevent it from touching the body and causing damage to the skin and eyes. If you accidentally touch it, quickly rinse with a lot of water and seek medical treatment.
The operating environment must be well ventilated. Volatiles of 1,3-difluoro-2-bromobenzene, or enter the human respiratory tract, are harmful to health. If it is well ventilated, it can reduce its concentration in the air and ensure the safety of the operator.
Furthermore, storage is also regulated. It should be stored in a cool, dry and ventilated place to avoid fire and heat sources. Do not mix with oxidants, strong alkalis, etc., to prevent violent reactions and cause danger.
When using, measure accurately and operate according to procedures. Reaction conditions such as temperature, time, and the proportion of reactants should be observed carefully. A slight aberration, or the reaction is out of control, will not only damage the product, but also cause danger.
Waste disposal should not be ignored. Used 1,3-difluoro-2-bromobenzene and related wastes should be properly disposed of in accordance with environmental regulations. Do not discard them at will to avoid polluting the environment.
In short, the safety and operation specifications of 1,3-difluoro-2-bromobenzene are the basis for chemical research and production. Only by following these regulations can we ensure safety, promote development, and avoid risk.
Application Area
1,3-Difluoro-2-bromobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be a key intermediate to help the creation of various special drugs, cure many diseases, and save patients from pain. In the context of material science, it can participate in the preparation of high-performance materials, which are endowed with specific properties, such as excellent stability and conductivity, and are suitable for high-tech products. In the field of fine chemicals, it can be used as raw materials for the synthesis of special chemicals to produce products with unique functions and increase the benefits of industrial production. From this perspective, 1,3-difluoro-2-bromobenzene has important value in various application fields and is indispensable for chemical research and industrial practice.
Research & Development
In recent years, I have dedicated myself to the research of 1,3-difluoro-2-bromobenzene. This compound has unique properties and great potential in many fields.
Initially, I studied its synthesis path and tried several times to find an effective method. Based on an aromatic compound, its molecular structure was gradually constructed through a series of reactions such as halogenation. However, the reaction conditions are harsh, and the temperature and reagent ratio need to be precisely controlled. If there is a slight difference, the yield will not be good.
Then, explore its physical and chemical properties. Determine its melting point and boiling point, and gain insight into its solubility in different solvents. Also study its reactivity with various reagents, paving the way for subsequent applications.
As for the development prospects, 1,3-difluoro-2-bromobenzene can be used as a key intermediate for the creation of new drugs and high-performance materials. I will continue to deepen my efforts to expand its application scope, contribute to the progress of the chemical field, and promote this compound from laboratory research to wide practical application, so as to benefit many industries.
Toxicity Research
1,3-Difluoro-2-bromobenzene is also an organic compound. Its toxicity study is related to the safety of our generation and cannot be ignored.
Now look at this 1,3-difluoro-2-bromobenzene, try to test its toxicity by various methods. In animal experiments, let the animal under test touch it, or eat it orally, or contact it with the skin, or make it inhale its gas. After observation, it can be seen that it may have an effect on various parts of the animal's body. For example, it may disturb the ability of its organs, the liver and kidneys, and the function of the genus can be seen; or disrupt its nervous system, causing different behaviors and reactions.
However, more research is needed to know the effect of its toxicity on the human body. We should be careful. When using this product, we should strictly abide by the regulations to prevent its harm to the body, to ensure the safety of the experiment, and to protect the health of everyone. Hopefully in the future, we will understand its nature better, and use it is beneficial but harmless.
Future Prospects
Today there is a thing named 1,3-difluoro-2-bromobenzene. I am a chemical researcher. Looking at this substance, I think about its future prospects, and I have a feeling.
This substance has unique properties and may open up new paths in the field of chemical industry. Its structure is exquisite, it contains fluorine and bromine, and has special activities. In the future world, science and technology will be new, and it may be able to use its characteristics to develop new drugs. The rise of medicine, or rely on this help to cure various diseases and save people from diseases.
And the progress of chemical materials, or rely on it. Special materials can be made, corrosion and heat resistance, and it is very useful in aerospace and electronics.
Although the road ahead is uncertain, I firmly believe that with time and unremitting research, 1,3-difluoro-2-bromobenzene will be able to bloom, contribute to the well-being of mankind, develop the grand future, and create unparalleled achievements.
Where to Buy 1,3-Difluoro-2-Bromobenzene in China?
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Frequently Asked Questions

As a leading 1,3-Difluoro-2-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-difluoro-2-bromobenzene?
1,3-Diene-2-alcohols have important uses in many fields. In the field of medicine, they are often used as key intermediates for the synthesis of various drugs. Due to their unique chemical structure, they can be precisely combined with other molecules through specific chemical reactions to build drug molecules with specific pharmacological activities. For example, in the synthesis of some anti-cancer drugs, the structural unit of 1,3-diene-2-alcohols can give drugs the ability to target cancer cells and inhibit their proliferation.
In materials science, 1,3-diene-2-alcohols can participate in the preparation of polymer materials. Through polymerization, it can be combined with other monomers to form polymers with special properties. These polymers may have good optical properties, thermal stability or mechanical properties, and can be used in optical materials, high temperature resistant materials, and other fields. For example, polymers synthesized from these compounds may play a role in the manufacture of high-transparency optical lenses or high-temperature resistant components in the aerospace industry.
In the field of synthetic organic chemistry, 1,3-diene-2-ol is an extremely important synthesizer. Because it contains multiple reactive check points, it can occur a variety of chemical reactions such as nucleophilic addition, electrophilic addition, and oxidation reduction. Organic chemists can use these reactions to ingeniously modify and transform their structures, and then synthesize organic compounds with complex structures and specific functions. In the total synthesis of natural products, 1,3-diene-2-ol is often used as a key intermediate to help realize the construction of complex natural product molecules, providing strong support for the research and development of new drugs and bioactive substances.
What are the physical properties of 1,3-difluoro-2-bromobenzene?
1% 2C3-diene-2-ol is an organic compound with unique physical properties. Although the "Tiangong Kaiwu" does not contain this specific compound, its physical properties can be described in ancient Chinese, as follows:
1% 2C3-diene-2-ol, at room temperature, or a colorless transparent liquid, the view is clear and pure, just like autumn water. Its smell may have a specific fragrance, and its fragrance is unique. It is like a flower in the forest quietly blooming, fresh and recognizable.
The density of this substance is slightly lighter than that of water. If it is placed in water, it can be seen that it floats on it, like a light boat floating on blue waves. Its boiling point or due to the characteristics of molecular structure, it is in a specific temperature range. When heated to the boiling point, it is like ice disappearing in the warm sun, gradually turning into a gaseous state and rising.
1% 2C3-diene-2-alcohol also has characteristics of solubility. In organic solvents, such as ethanol, ether, etc., it can be well miscible, just like water emulsion, indistinguishable from each other. However, in water, its solubility is limited, and it can only be partially dissolved, like oil droplets in water, and it is difficult to form a uniform state.
Its volatility is also quite considerable. In an open container, let it stand for a while, and it can be seen that the amount is gradually decreasing. If morning dew meets sunlight, it slowly dissipates. This is due to the thermal movement of molecules, which makes it easy to change from liquid to gaseous and escape into the air.
In addition, the viscosity of 1% 2C3-diene-2-ol is slightly higher than that of water. When flowing, it is like a slow stream, which is not as light and smooth as water, and it is slightly dignified.
What are the synthesis methods of 1,3-difluoro-2-bromobenzene?
The synthesis method of 1% 2C3-diene-2-ol, although the synthesis of this specific compound is not detailed in "Tiangong Kaiwu", it contains many traditional chemical process ideas, which can be used for reference for modern synthesis ideas.
Ancient chemical synthesis often depends on the characteristics and changing laws of natural raw materials. Synthesis of 1% 2C3-diene-2-ol, if considered by ancient methods, or first find natural products rich in enol structure. For example, some vegetable oils and flavors can be specially treated, or enols can be obtained.
First, plant extracts with suitable carbon chains and unsaturated bonds can be found. After preliminary separation by extraction, distillation, etc., crude products containing target structures can be obtained. For example, the method of extraction and separation is mentioned in the article "making salty" and "paste liquid" in "Tiangong Kaiwu", or it can be borrowed here. First extract with water or organic solvent, then heat distillation, and separate according to the difference in boiling point.
Second, use microbial fermentation. The fermentation process of ancient wine brewing, sauce making is mature. Specific microorganisms can be screened and cultured with suitable carbon sources and nitrogen sources to metabolize and produce enol-containing structural products. Adjust fermentation conditions, such as temperature, pH, and ventilation, to optimize product generation.
Third, chemical transformation. Using natural alkenes and simple alcohols as starting materials, the target structure is constructed through reactions such as addition and elimination. Although the ancient method lacks the concept of modern precise organic reaction, operations such as acid-base interaction and heating changes can lead to reactions. For example, plant bases or mineral acids are used as catalysts to promote the reaction.
However, the limitations of the ancient method are also clear. Analysis and detection methods are lacking, and it is difficult to precisely control the reaction process and product purity. Modern synthesis technologies can be monitored by gas chromatography, mass spectrometry, etc., and nuclear magnetic resonance can determine the structure. However, the inspiration of the ancient method is still there. Starting from natural resources, it is green and sustainable, providing multiple perspectives for the synthesis of 1% 2C3-diene-2-alcohol, fusing ancient and modern, or developing new synthesis paths.
What are the precautions for storing and transporting 1,3-difluoro-2-bromobenzene?
1% 2C3-diene-2-alcohol is a chemical substance. When storing and transporting, it is necessary to pay attention to many key matters.
First, when storing, you need to choose a cool and well-ventilated place. This is because it is volatile to a certain extent. If the storage environment temperature is too high or the ventilation is poor, it is easy to cause its volatilization and accumulation, or risk safety. And keep away from fires and heat sources. Because the substance may be flammable, it may cause combustion or even explosion when exposed to open flames and hot topics.
Second, it should be stored separately from oxidants and acids, and must not be mixed. The chemical properties of 1% 2C3-diene-2-alcohol are active, contact with oxidants, or severe oxidation reactions; contact with acids, chemical reactions may also occur, causing material deterioration, and or accompanied by dangerous conditions.
Third, when transporting, be sure to ensure that the container is well sealed. If the container is not well sealed, it will be bumpy and vibrated during transportation, which will easily cause material leakage, not only polluting the environment, but also posing a threat to the safety of transporters. Transportation vehicles should also be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment for emergencies.
Fourth, during transportation, the driving speed should not be too fast, and violent operations such as sudden braking and sharp turns should be avoided. This causes leakage due to severe vibration or impact, or damage to the storage container. And the transportation route should try to avoid densely populated areas and important facilities to reduce the possible hazards caused by accidents.
In short, 1% 2C3-diene-2-ol must strictly follow relevant safety regulations and operating procedures during storage and transportation to ensure personnel safety, environmental safety and the quality of the substance itself.
What is the market price range for 1,3-difluoro-2-bromobenzene?
1% 2C3-diene-2-alcohol naphthalene, its market price is low, and it can be improved as a whole. The quality of the product often varies for various reasons, such as the quality of the material, the complexity of the method, the amount of need, and the quality of the product.
If the supply of materials is sufficient, and the method of improving the product is convenient and easy to apply, it will be difficult to improve the quality of the product. However, if the raw materials are rare and available, the quality of the product will be high. Moreover, if the world needs this product, the demand for supply will also rise; on the contrary, if the demand is small, the supply will inevitably decline.
Furthermore, the security of the market and the blockage of the trade route are also important. In a peaceful world, the trade route is difficult, and the logistics is difficult to pass, or it is difficult to achieve. If you encounter the world, the trade route is blocked, and the cost is greatly increased, the cost will be greatly increased, and the price will be improved.
is to know the market of 1% 2C3-diene-2-alcohol naphthalene, and to observe the general situation of the next situation. Only in the market can we obtain its approximate value, but it can also be maintained for a long time.