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1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene

1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

853692

Chemical Formula C6HCl2F2NO2
Molar Mass 229.97 g/mol
Appearance Solid (likely white or off - white powder)
Melting Point Data may vary, but needs research for exact value
Boiling Point Data may vary, but needs research for exact value
Solubility In Water Low solubility (organic compound, non - polar nature)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Density Data may vary, but needs research for exact value
Vapor Pressure Low vapor pressure due to its solid state at room temperature
Stability Stable under normal conditions, but reactive with strong reducing agents or bases

As an accredited 1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing Packed in 500 - gram bottles: 1,3 - dichloro - 2,4 - difluoro - 5 - nitrobenzene.
Storage 1,3 - Dichloro - 2,4 - difluoro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly - sealed container to prevent moisture absorption and vapor leakage. Label the storage clearly to ensure proper handling and safety.
Shipping 1,3 - Dichloro - 2,4 - difluoro - 5 - nitrobenzene is a chemical. It should be shipped in tightly sealed, corrosion - resistant containers, following strict hazardous materials regulations, ensuring proper labeling and safe handling during transit.
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1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene 1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene
General Information
Historical Development
1,3-Dichloro-2,4-difluoro-5-nitrobenzene is also a chemical product. At the beginning of its inception, it really relied on the research of all kinds of chemical talents. At that time, everyone worked hard to explore the origin and changes of this product by chemical methods.
In the initial stage, everyone explored and moved forward, wanting to understand its characteristics and the method of preparation. After years, countless experiments, or failures, or small achievements, but they never gave up. Gradually, progress has been made in the method of synthesis, knowing what raw materials and steps can be taken to obtain this product.
As the years pass, its use has gradually become known to the world. In the fields of chemical industry, it gradually shows its ability, either as a raw material or as a boost, contributing to the prosperity of many industries. From the initial ignorance and exploration, to the wide application today, the development of 1,3-dichloro-2,4-difluoro-5-nitrobenzene is a good example of research and progress in the field of chemistry.
Product Overview
Today, there is a substance called 1,3-dichloro-2,4-difluoro-5-nitrobenzene. This substance is color-specific and unique in nature. It is obtained from the intensive study of chemistry and has a specific structure. Viewing its shape, it is either in the form of powder or in the state of crystallization.
In the field of chemical synthesis, its effectiveness is significant. It can be used as a key raw material to help create a variety of compounds. Its reactivity is determined, and it comes into contact with various reagents, changing according to a specific mechanism, resulting in the generation of new substances.
However, this substance also needs to be handled with caution. Because it is dangerous, or harmful to the human body, or affects the surrounding environment. Therefore, when handling, we must follow the standard law and strictly observe the safety rules to ensure safety. This is a brief description of 1,3-dichloro-2,4-difluoro-5-nitrobenzene.
Physical & Chemical Properties
1,3-Dichloro-2,4-difluoro-5-nitrobenzene is also a chemical substance. Its physical and chemical properties are very important to study. Looking at its shape, at room temperature, it may be solid, colored or light yellow. Its melting and boiling point is determined by the force between molecules, and has a specific value. As for solubility, it is insoluble in organic solvents or has a certain degree of solubility, but it is insoluble in water, which is determined by its molecular polarity. Its chemical activity is unique because it contains chlorine, fluorine, nitro and other groups. The strong electron absorption of nitro groups reduces the density of electron clouds in the benzene ring, making it difficult to cause electrophilic substitution, but it is easy to cause nucleophilic substitution. Chlorine and fluorine atoms can also participate in many reactions and affect their chemical properties. In chemical research, understanding their physical and chemical properties can make good use of them, making new substances and expanding their uses. In the field of chemistry, it is of great significance.
Technical Specifications & Labeling
Today there is a product named 1,3-dichloro-2,4-difluoro-5-nitrobenzene. The method of its preparation is crucial to the technical specifications and identification (commodity parameters). To obtain this product, a certain rule must be followed. Prepare all kinds of raw materials first, according to the appropriate proportion, and combine them with precise techniques. At the time of reaction, control its temperature and adjust its pressure to ensure a smooth reaction. After the reaction is completed, it has been refined, and the impurities have been removed and kept pure to obtain a good product.
Look at its logo and note all the parameters in detail. If there is a number of purity, the geometry of impurities is clear on the logo. This is the evidence for distinguishing the pros and cons, and it is also the basis for trade transactions. Merchants who hold this logo can know the quality of its high and should not use it. Therefore, technical specifications and labels (commodity parameters) are indispensable for the production and use of 1,3-dichloro-2,4-difluoro-5-nitrobenzene.
Preparation Method
The preparation method of 1,3-dichloro-2,4-difluoro-5-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical, and the commonly used ones are specific halogenated aromatics and compounds containing fluorine and nitro groups. The production process requires precise control of reaction conditions, such as temperature, pressure and reaction time.
The first step is the halogenation reaction. Under the action of suitable solvents and catalysts, halogen atoms are introduced into the aromatic hydrocarbon structure. Subsequent to the fluorination reaction, some halogen atoms are replaced by a specific fluorine source, which requires strict reaction conditions. Furthermore, the nitrogenation reaction introduces nitro groups to achieve the target molecular structure. In the
catalytic mechanism, the selection of high-efficiency catalysts can accelerate the reaction process and increase the yield. Specific metal salts or organometallic complexes are often used as catalysts, which interact with the reactants to reduce the activation energy of the reaction. Each step is closely related and needs to be carefully regulated to obtain high-purity 1,3-dichloro-2,4-difluoro-5-nitrobenzene products.
Chemical Reactions & Modifications
Today, there is a substance named 1,3-dichloro-2,4-difluoro-5-nitrobenzene. In the way of chemical research, its reaction and modification are the key.
Looking at this compound, chlorine, fluorine, nitro and other groups coexist and interact with each other, resulting in its unique reaction characteristics. Its reactivity is related to the electronic effect and steric resistance of each group. The strong electronegativity of fluorine reduces the electron cloud density of the benzene ring and increases the difficulty of electrophilic substitution reaction. Although chlorine is also electron-absorbing, it is affected differently by factors such as atomic radius. Nitro is a strong electron-absorbing group, which left and right the reaction path.
As for modification, or introduce new groups to change their physical and chemical properties. Or by substitution reaction, it is easy to remove a certain group and replace it with others to obtain the desired properties. All of this requires detailed study of the reaction mechanism and control of the reaction conditions, such as temperature, solvent, catalyst, etc., in order to achieve the purpose of optimizing modification, adding new colors to the chemical field and opening up new applications.
Synonyms & Product Names
1,3-Dichloro-2,4-difluoro-5-nitrobenzene is also the essence of chemistry. The name of this thing is different but there are many people who agree with it. Or "dichlorodifluoro-nitrobenzene", although its position order is omitted, its quality has not changed; or it is called "chlorofluoro-nitrobenzene variant", because its structure contains chlorine, fluorine and nitro groups.
The name of the goods in the market is also various. Some are named because of their nature, called "highly reactive chlorofluoro-nitrobenzene", in recognition of its active state in the process of chemical reactions; there are also names for their use, called "special chlorofluoro-nitrobenzene", indicating its ability to adapt to various domains.
Although the names are different, they are actually the same. They are all the names of this wonderful thing. Chemists distinguish their properties and study their uses. The differences in names should also be clear, so as not to be wrong.
Safety & Operational Standards
Safety and Operating Specifications for 1,3-Dichloro-2,4-difluoro-5-nitrobenzene
F 1,3-dichloro-2,4-difluoro-5-nitrobenzene is an important substance in chemical research. If you want to use this substance, the first priority is safety, and you can be safe by following the operating specifications.
In the method of storage, find a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Because it has certain chemical activity, if it is heated or exposed to open flames, it may be dangerous. And it should be stored separately from oxidizing agents, reducing agents, acids, alkalis, etc., and must not be mixed to prevent interaction and cause harm.
As for the operation, the operator must wear appropriate protective equipment. Wear protective clothing to prevent this object from touching the skin and causing damage to the skin. Wear protective gloves to avoid direct contact. And when wearing protective glasses, protect your eyes from damage. In the operation room, ventilation equipment must be complete to make the air smooth to prevent the accumulation of harmful gases.
When taking 1,3-dichloro-2,4-difluoro-5-nitrobenzene, the action should be slow and careful. Do not shake or pour violently to avoid spilling. When weighing, be sure to use a precise instrument and take the amount according to the experimental requirements. Do not be greedy or take by mistake. If it is accidentally spilled, do not panic. Quickly evacuate unrelated personnel from the scene and turn on the ventilation device at the same time. Cover the spill with appropriate materials, such as sand, to avoid its spread. Then, in accordance with relevant regulations, properly clean up and collect, and do not discard it at will.
Furthermore, after use, the utensils used must be cleaned in time. 1,3-dichloro-2,4-difluoro-5-nitrobenzene remaining on the utensils should not be retained to prevent the next use from affecting the experimental results and preventing it from corroding the utensils.
In short, in the use of 1,3-dichloro-2,4-difluoro-5-nitrobenzene, safety and operation standards are as indispensable as the two wheels of a car and the wings of a bird. Only by following these two can the road of chemical research be stable and far-reaching.
Application Area
1,3-Dichloro-2,4-difluoro-5-nitrobenzene, this compound has a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to assist in the preparation of many specific drugs to treat various diseases and benefit patients. In the field of materials science, with its unique chemical structure, it can participate in the creation of high-performance materials, improve the characteristics of materials, such as stability and durability, so that the materials can perform well in different environments. It is also of great value in the research and development of pesticides, and may lay the foundation for the birth of new and efficient pesticides, help agricultural pests and increase production, protect crops and protect people's livelihood.
Research & Development
Today there is a product named 1,3-dichloro-2,4-difluoro-5-nitrobenzene. As a chemical researcher, I am dedicated to the research and development of this product.
Looking at the structure of this compound, chlorine, fluorine, and nitro are cleverly connected, which seems to contain endless mysteries. Its reactivity is unique, or it has extraordinary potential for the preparation of new materials and special drugs.
I often think about how to optimize the synthesis method to improve the yield and purity. After repeated experiments, adjusting the temperature, pressure, and catalyst, I have gradually gained something. Although the process is difficult, every progress is very happy.
I firmly believe that with time and in-depth investigation, this product will surely shine in the chemical industry, contribute to human well-being, promote the progress of science and technology, and open a new chapter.
Toxicity Research
Study on the toxicity of 1,3-dichloro-2,4-difluoro-5-nitrobenzene
If 1,3-dichloro-2,4-difluoro-5-nitrobenzene, it is also a chemical substance. Today to explore its toxicity, this is the work of the researchers in our chemical industry.
To observe its toxicity, chlorine, fluorine, and nitro are poly-benzene. Nitro is active and toxic, or induces protein resistance and enzyme inactivation. The base of chlorofluorine also increases its lipid solubility, and it is easy to enter the biofilm, which is the order of physiology.
It is used to replace the substance, and it is used to contain this substance. Not long after, he was tired, he ate, and his fur lost. His blood, biochemical fingers, and liver energy are good.
In addition to plants, this substance is found in the soil, its growth, color, or due to the process of photosynthesis and respiration.
Therefore, 1,3-dichloro-2,4-difluoro-5-nitrobenzene is toxic and harmful to biological life and substitution. Our researchers are cautious, seeking safety for use, and avoiding harm in the realm of living things.
Future Prospects
The chemical compound of 1,3-dichloro-2,4-difluoro-5-nitrobenzene is also a chemical compound. Today, it has general characteristics and can be used in general. In the future, there is no world.
This compound has special properties and may be used in new research. With its special manufacturing, or it can be used in a new way, it has the power to eliminate diseases and treat diseases. And in the field of materials, it is also expected to show great colors. It can be used as the cornerstone of special materials. With new energy, the material can improve its performance, corrosion resistance and other properties.
I am a research researcher, studying its properties and digging deeper. In a few days, the use of 1,3-dichloro-2,4-difluoro-5-nitrobenzene will be improved, which will benefit the world and make the unseen scene new. This is our hope.
Where to Buy 1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene in China?
As a trusted 1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dichloro-2,4-Difluoro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-dichloro-2,4-difluoro-5-nitrobenzene?
1% 2C3-dihydro-2% 2C4-diene-5-carboxybenzene has important uses in many fields.
In the field of medicinal chemistry, this compound is often used as a key intermediate. Due to its specific chemical structure, it can participate in a variety of chemical reactions and assist in the synthesis of drug molecules with unique pharmacological activities. For example, when developing some anti-tumor drugs, 1% 2C3-dihydro-2% 2C4-diene-5-carboxybenzene can be used as a starting material. Through a series of carefully designed reaction steps, other biologically active groups can be connected to construct drugs that target tumor cells and interfere with the growth, proliferation and metastasis of tumor cells.
In the field of materials science, it also plays an important role. With its special conjugate structure and functional groups, it can be used to prepare functional polymer materials. For example, polymers with photoelectric properties can be synthesized by polymerizing with specific monomers. This type of polymer can be used in organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to improve the luminous efficiency and energy conversion efficiency of the devices.
In organic synthetic chemistry, 1% 2C3-dihydro-2% 2C4-diene-5-carboxylbenzene is an extremely useful synthetic building block. Chemists use its double bond and carboxyl group reactivity to carry out various organic reactions, such as esterification reactions, nucleophilic addition reactions, etc., to construct complex and diverse organic molecules, providing a rich material basis and new synthetic paths for the development of organic synthetic chemistry.
What are the physical properties of 1,3-dichloro-2,4-difluoro-5-nitrobenzene?
1% 2C3-difluoro-2% 2C4-dichloro-5-trifluoromethylbenzene, this material has unique physical properties. It is mostly liquid at room temperature, with high volatility and rapid diffusion in the air. Due to the presence of many halogen atoms, the special forces between molecules cause the boiling point and melting point to be affected. Generally speaking, the boiling point is in a specific range, and the melting point is also in a certain range. This characteristic makes its physical state variable under different temperature conditions, which is an increasing variable for practical applications.
Its density is greater than that of common organic solvents. When mixed with water, it is stratified due to density differences. In terms of solubility, it is soluble in a variety of organic solvents, such as aromatics and halogenated hydrocarbons, but it is difficult to dissolve in water. This difference in solubility is due to the interaction between halogen atoms and organic groups in its molecular structure, which affects the interaction with different solvent molecules.
It also has low surface tension, which is easy to spread on the surface of liquids, and is useful in some scenarios that require good wettability. Its vapor pressure also has characteristics. The high vapor pressure at a specific temperature means that its evaporation rate is relatively fast. When using it, it is necessary to pay attention to this property and take protective measures to ensure safe operation. The above physical properties are of great significance in the fields of chemical synthesis, materials science, and pharmaceutical research and development. According to their characteristics, researchers can design reactions, optimize processes, and develop new materials, allowing them to emit light and heat in various fields.
What are the synthesis methods of 1,3-dichloro-2,4-difluoro-5-nitrobenzene?
There are various methods for the synthesis of 1% 2C3-dioxy-2% 2C4-diene-5-carbonylbenzene. One is to start with benzene and go through a multi-step transformation. First, the benzene is exposed to a specific acylating agent, and a suitable catalyst such as anhydrous aluminum trichloride is stored, and the Fu-gram acylation reaction is performed to obtain acylbenzene. Next, the acylbenzene is combined with a specific halogenating agent to halogenate at a specific location on the benzene ring to obtain halogenated acylbenzene. Then, the target product 1% 2C3-dioxy-2% 2C4-diene-5-carbonylbenzene can be obtained by a series of reactions such as nucleophilic substitution and cyclization under alkali catalysis.
The second method can be derived from a compound with a similar structure. Take a compound containing a benzene ring and has a modifiable functional group, and protect its functional group first to prevent unnecessary side reactions during the reaction. Then use an appropriate oxidant or reducing agent to adjust the oxidation state of a specific functional group, and then go through the steps of condensation and cyclization to obtain this product. When condensing, it is necessary to pay attention to the reaction conditions, such as temperature, solvent and the ratio of reactants, to ensure that the reaction proceeds in the expected direction. The cyclization step often relies on nucleophilic attack within the molecule to form a cyclic structure of 1% 2C3-dioxy-2% 2C4-diene-5-carbonylbenzene.
And those who start with the concept of green chemistry choose mild reaction conditions and environmentally friendly reagents and solvents. For example, using water as a solvent, or using ionic liquids instead of traditional organic solvents, by enzyme catalysis or photocatalysis to promote the reaction. These new methods not only reduce waste, but also often produce products under milder conditions, avoiding harsh conditions such as high temperature and high pressure in traditional methods, and also have low equipment requirements. They are expected to create a new path for the synthesis of 1% 2C3-dioxy-2% 2C4-diene-5-carbonylbenzene.
What are the precautions for storing and transporting 1,3-dichloro-2,4-difluoro-5-nitrobenzene?
When storing and transporting 1% 2C3-dioxy-2% 2C4-diene-5-carboxybenzene, many things need to be paid attention to.
First, this substance may have an impact on the environment. When storing, be sure to choose a place far away from water sources and farmland to prevent inadvertent leakage, pollution and soil, harm and life. When transporting, also avoid passing through rivers, lakes and other water sources, and be careful to protect the safety of nature.
Second, 1% 2C3-dioxy-2% 2C4-diene-5-carboxybenzene is chemically active and dangerous when exposed to heat, open flames or oxidants. Storage should be in a cool, dry and well ventilated place, away from heat sources and fires. Transportation vehicles should be equipped with fire extinguishing and leakage emergency treatment equipment. In case of fire, appropriate fire extinguishing agents should be used to rescue.
Third, because it may be toxic and irritating, contact is harmful to the human body. Storage and transportation personnel must wear protective clothing, protective gloves and masks to prevent skin, respiratory tract and eye contact. When loading and unloading, the action should be slow to avoid leakage due to package damage.
Fourth, the storage and transportation of 1% 2C3-dioxy-2% 2C4-diene-5-carboxylbenzene are strictly regulated by regulations. Records must be kept in accordance with relevant regulations, such as quantity, source, destination, etc. Transport requires a license, following the specified route and time, to ensure the orderly compliance of the whole process. In this way, 1% 2C3-dioxy-2% 2C4-diene-5-carboxybenzene is stored and transported safely.
What is the market price of 1,3-dichloro-2,4-difluoro-5-nitrobenzene?
1% 2C3-difluoro-2% 2C4-dichloro-5-fluoromethylbenzene, the price of this compound in the market is difficult to determine. The change in its price is influenced by many reasons.
One is related to raw materials. The abundance of raw materials and the price of raw materials have a great impact on the cost of production. If the raw material is rare and expensive, the production cost of this compound will increase, and the price of the compound in the market will also rise.
Second, it involves the process. If the production process is difficult, exquisite equipment and superb skills are required, which will also increase the cost and cause the price to be high. And the refinement of the process, if it can reduce consumption and increase efficiency, it may reduce the price.
Third, it depends on demand. If the market demand for this product is strong and the supply is limited, the price will increase according to the reason of supply and demand. On the contrary, if the demand is weak and the supply is sufficient, the price may drop.
Fourth, the impact of policies and regulations cannot be ignored. The strictness of environmental regulations will affect the cost of production and the operation of enterprises, and then affect the price of this product.
Therefore, in order to determine the market price of 1% 2C3-difluoro-2% 2C4-dichloro-5-fluoromethylbenzene, it is necessary to observe the status of raw materials, the progress of the process, changes in market supply and demand, and policy guidance in real time.