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1,3-Dibromo-5-Fluorobenzene

1,3-Dibromo-5-Fluorobenzene

Hongda Chemical

Specifications

HS Code

256686

Chemical Formula C6H3Br2F
Molar Mass 255.9
Appearance Colorless to light yellow liquid
Boiling Point 195 - 197 °C
Density 1.944 g/mL at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Refractive Index 1.599

As an accredited 1,3-Dibromo-5-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - dibromo - 5 - fluorobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1,3 - Dibromo - 5 - fluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of a material resistant to chemical corrosion, like glass or certain plastics. This helps prevent leakage and degradation, ensuring its stability during storage.
Shipping 1,3 - Dibromo - 5 - fluorobenzene, a chemical, is shipped in specialized, leak - proof containers. Packaging ensures protection from physical damage. Shipments follow strict regulations due to its potentially hazardous nature.
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1,3-Dibromo-5-Fluorobenzene 1,3-Dibromo-5-Fluorobenzene
General Information
Historical Development
1,3-Dibromo-5-fluorobenzene is also an organic compound. At the beginning of its exploration and research, it was only one of the many chemicals. In the past, chemists were thirsty for knowledge, and they tried their best in the field of organic synthesis. At that time, although the conditions were simple, they were determined to persevere.
First, they only knew the basics of it, and then with the improvement of skills, they gradually gained insight into its structure. Scientific researchers, in the laboratory, operate day and night, or adjust the temperature, or control the pressure, and observe its changes. After years of work, they can accurately make it. This compound was originally only the object of academic research, and soon became increasingly useful in the fields of medicine and materials. It was like a pearl that had just appeared, shining brightly, opening up a new path for chemical applications, leading the direction of scientific research, and adding a strong touch to the process of chemical history.
Product Overview
1,3-Dibromo-5-fluorobenzene is a unique type of organic compound. What is its shape? It is often a colorless to light yellow liquid or solid with a special odor. The structure of this compound is quite delicate. It is based on a benzene ring, and the bromine atom and fluorine atom on it occupy a specific position, one at 1, 3, and one at 5, and the layout is well.
It has a wide range of uses and is an important intermediate in the field of organic synthesis. Chemists often use this as a basis to produce a variety of valuable products through various reactions, or in pharmaceutical research and development, to help create new drugs; or in materials science, it is a key starting point for the synthesis of special materials.
However, the preparation of this compound is not easy, and it is necessary to precisely control the reaction conditions, such as temperature, reagent ratio, etc. If there is a slight difference, it is difficult to achieve the desired result. Looking at its properties and applications, it is actually an existence that cannot be ignored in chemical research.
Physical & Chemical Properties
1,3-Dibromo-5-fluorobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, it is a colorless to light yellow liquid at room temperature, with a specific taste and certain volatility. Its boiling point is about a certain range, and its melting point also has a specific value, which is related to the transformation of its physical state.
Discuss chemical properties, because it contains bromine and fluorine atoms, it is active. Bromine atoms can participate in nucleophilic substitution reactions, and are easily replaced when encountering nucleophilic reagents. Fluorine atoms have strong electronegativity, which affects the distribution of molecular electron clouds, so that the compound exhibits unique activity in specific reactions. And its structure is stable, and it can participate in a variety of organic synthesis reactions under certain conditions. It is an important intermediate for the preparation of complex organic compounds and has a wide range of uses in the field of organic chemistry.
Technical Specifications & Labeling
1,3-Dibromo-5-fluorobenzene Technical Specifications and Labeling (Product Parameters)
There is currently 1,3-dibromo-5-fluorobenzene, and its technical regulations need to be rigorous. When preparing, the raw materials must be selected with purity and accurate proportions. The reaction conditions are also critical. The temperature should be controlled within a certain range, the fluctuation should not exceed the limit, and the pressure must be stable. The reaction time should be in sequence and should not be rushed.
In terms of labeling, the name of 1,3-dibromo-5-fluorobenzene should be prominently written on the product label. Its molecular formula, molecular weight and other parameters are clearly identifiable. Indicate the purity geometry and the impurity content geometry. It is accompanied by a warning label to inform the user of its chemical properties and the importance of protection, so that the user can understand the characteristics of this object and be cautious when operating, so that the product is excellent and safe to use.
Preparation Method
The method of making 1,3-dibromo-5-fluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is the key, and the product with pure texture needs to be carefully selected. In the production process, strict procedures should be followed. First take an appropriate amount of fluorobenzene, supplemented by a specific brominating agent, and put it into the reactor according to the precise ratio. Adjust the temperature to a suitable range, which is the key to the reaction. If the temperature is high, the side will be anti-clustered, and if the temperature is low, the reaction will be slow. Stir in a timely manner to make the material blend evenly.
The reaction steps must also be cautious. In the initial stage, the brominating agent and fluorobenzene gradually react, observe the signs, and observe the changes in When the reaction is stable, fine-tune the conditions to promote it to the right path.
The catalytic mechanism is indispensable, and the catalyst can be selected to increase the production rate. The beauty of catalysis is to lower the reaction barrier, increase the molecular activity, and the collision is efficient, resulting in a smooth reaction. The 1,3-dibromo-5-fluorobenzene obtained in this way can be of high quality and meet the required standards.
Chemical Reactions & Modifications
The chemical and reverse modification of 1,3-dibromo-5-fluorobenzene is important for chemical research. In the past, in order to obtain this product, it was often used as a simple method. Its initial reaction, or according to the ancient method, with phenyl, bromination and fluorination. However, such a method has many drawbacks. The reverse parts are harsh, either high or high, and the yield is unsatisfactory. The secondary reaction is produced, and the resulting product is not low.
Today's new products are intended to be innovative. Intervention with catalysis to change the reverse route. Under the new catalytic system, the reverse parts can be mixed together, and they can also be used often. And the efficiency is greatly increased, the secondary reaction is less, and the quality of the product can be improved. This modification, in the development of 1,3-dibromo-5-fluorobenzene, is of great significance, making this product more convenient and efficient, and also developing new technologies.
Synonyms & Product Names
1,3-Dibromo-5-fluorobenzene is also a chemical substance. Its name is the same, and it is also noted by the person. This substance may have a name, and it all means the same. The ancients said: "Those who are famous, those who are not." The same name of 1,3-dibromo-5-fluorobenzene, in chemical research, if the guidance of the stars, help researchers to understand its origin. Its trade name also recognizes its value in commercial circulation. Both are the same name of this substance, and the name is the same. Communicate with those who help with the same name, and the trade name will be in the market. It is based on the same name and trade name of 1,3-dibromo-5-fluorobenzene, and the process of jointly promoting research and commercial use.
Safety & Operational Standards
1,3-Dibromo-5-fluorobenzene is also one of the chemical products. During its experiment and production, safety and operating standards are of paramount importance and cannot be ignored.
The first way to be safe is to protect. Those involved in this chemical must wear suitable protective equipment. Masks are used to protect the breath and prevent its volatilized gas from entering the body and causing respiratory diseases; gloves are used to protect the hands, avoid skin contact and avoid chemical burns; goggles are also indispensable to protect the eyes from accidental splashing.
Times and storage rules. 1,3-Dibromo-5-fluorobenzene should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent it from decomposing due to heat and causing danger. And it should be stored in separate stores with oxidants and alkalis to avoid their interaction and cause violent reactions.
As for the operation process, it is necessary to abide by the specifications. Operate in the fume hood to allow the volatile gas to be discharged in time and reduce its concentration in the air. When taking it, measure it with precise instruments, not more or less, to ensure the accuracy of the experiment, but also to avoid waste and danger. After the operation, properly clean the site, and dispose of the residue according to regulations. Do not dispose of it at will, and avoid polluting the environment.
In addition, emergency measures also need to be familiar with the heart. If the skin touches it, rinse it with a lot of water quickly, and then treat it with a medical agent; if it enters the eye, rinse it immediately and seek medical attention quickly. In case of fire, choose appropriate fire extinguishing materials according to their nature, and must not act blindly.
In short, in all matters related to 1,3-dibromo-5-fluorobenzene, safety must be taken as the priority, and operating standards must be strictly followed in order to ensure people's safety, smooth affairs, and promote the order of scientific research and production.
Application Area
Today there is a thing called 1,3-dibromo-5-fluorobenzene. This compound has special properties in various application fields.
In the field of pharmaceutical research and development, it can be a key intermediate. Physicians want to make special and good medicines, often rely on this to start the process of synthesis. With its unique structure, it can lead to the aggregation and order of drug molecules, so that the drug power can accurately reach the focus and remove diseases.
In the field of materials science, it is also extraordinary. It can integrate new materials, increase its stability and improve its optical properties. Such as the preparation of photoelectric materials, can make better light conduction, more colorful, for lighting, display industries, add new power.
In addition, in the field of fine chemicals, 1,3-dibromo-5-fluorobenzene is also indispensable. Help chemical craftsmen prepare delicate formulas, produce high-quality fine products, and contribute to the development of industry. It is actually an important material for a wide range of applications.
Research & Development
Wutao is dedicated to the research of 1,3-dibromo-5-fluorobenzene. This compound has unique properties and great potential in the field of organic synthesis. At the beginning, we explored the method of its preparation, but encountered various problems such as rare raw materials and harsh reaction conditions. However, we and our colleagues worked tirelessly and tried different paths repeatedly, and finally obtained the optimization method to improve the yield and purity.
Then, we considered its application and expansion. After many explorations, we found that it can play a key role in the development of new drugs and the creation of functional materials. Today, although we have achieved results, we know that the road ahead is still long. In the future, by continuously refining the preparation process, reducing costs, and exploring its potential applications, we hope to promote progress in related fields, contribute to scientific development, and make the research and development of 1,3-dibromo-5-fluorobenzene a new frontier.
Toxicity Research
Since modern times, in the field of chemistry, there is a substance called "1,3 - Dibromo - 5 - Fluorobenzene", and the investigation of its toxicity is related to many things. Our generation of chemical researchers should investigate it carefully.
This substance may have a certain appearance, but its internal toxicity must be investigated carefully. Or it has potential effects on the physiological functions of organisms. After various experiments, observe its interaction with various biological tissues and observe its reactions.
Some studies have shown that it may interfere with the normal metabolic pathways at the cellular level, causing disorders in cellular functions. Or in the whole animal body, it may cause abnormalities in physiological indicators.
Although the confirmation of toxicity still requires more rigorous experiments and demonstrations, it should not be ignored. Our chemical researchers must be cautious and continue to study, to make sure that the toxicity is clear, and to provide a detailed basis for the world to use this substance, to avoid its harm and promote its benefits, and to live up to the researcher's responsibility.
Future Prospects
Today there is a thing named 1,3-dibromo-5-fluorobenzene. Looking at this thing, although it is not in an extraordinary state at the moment, it has infinite prospects in the future.
This compound has a unique structure, and its bromine and fluorine atoms endow it with unique chemical properties. In the field of organic synthesis, it may be a key building block. In the future, with the increasing progress of organic synthesis technology, it may be possible to build many complex and delicate molecules, which can be used in medicine, or can be used as a medicine to cure diseases and save people; used in materials science, or to create new materials with excellent performance.
Although the current research is not extreme, the rapid development of science and technology, with time, the understanding of it will become more and more profound. At that time, 1,3-dibromo-5-fluorobenzene will be shining brightly, creating new trends in various fields, contributing to human well-being, and achieving extraordinary achievements. This is my vision for its future.
Where to Buy 1,3-Dibromo-5-Fluorobenzene in China?
As a trusted 1,3-Dibromo-5-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dibromo-5-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-dibromo-5-fluorobenzene?
Although 1,3-dibromo-5-chlorobenzene is not directly recorded in "Tiangong Kaiwu", it is deduced from the ancient chemical industry, medicine, dyeing and weaving industries, and its uses may have the following ends.
In chemical synthesis, it can be an important intermediate. Ancient alchemy and early pharmaceuticals were often based on various minerals and plants, and new products were prepared through complex reactions. 1,3-dibromo-5-chlorobenzene has active chemical properties, or involves aromatic ring substitution, addition and other reactions. For example, ancient pigments may need to be made from them, and through multi-step transformation, fresh and stable pigments can be obtained for calligraphy, painting, dyeing and weaving.
In the field of medicine, there is also potential value. Ancient healers treated diseases, and often used herbs and golden stones as medicine. 1,3-Dibromo-5-chlorobenzene or after processing and compatibility, has the effects of sterilization and anti-inflammation. Although the ancients did not have modern precise pharmacological knowledge, they found in practice that compounds containing such structures are effective for some diseases. Such as swelling of sores and toxins, the external application of the agent participated in the preparation may inhibit the growth of bacteria and help the wound heal.
Dyeing and weaving industry, or as a mordant. In ancient dyeing cloth, in order to make the color firm and uniform, mordants were often used. 1,3-Dibromo-5-chlorobenzene may be able to combine with fabric fibers and dyes to enhance the adhesion of dyes, so that dyed fabrics can be washed in the sun without fading, and meet the needs of the ancients for the beauty and durability of clothing and fabrics.
In summary, although 1,3-dibromo-5-chlorobenzene is not detailed in "Tiangong Kaiwu", it is still based on the development of ancient technologies and the commonality of chemical substances. It may have important uses in chemical, pharmaceutical, dyeing and weaving industries, etc., adding luster to the life and production of the ancients.
What are the physical properties of 1,3-dibromo-5-fluorobenzene?
1% 2C3-dibromo-5-pentyne is an organic compound with special physical properties. Although "Tiangong Kaiwu" does not directly describe this substance, it can be described in Chinese according to the method of the ancients.
Under normal temperature and pressure, it is a colorless to light yellow liquid. It has a clear state, like morning dew condensation, and its luster is restrained. Smell it, there is a pungent smell, like being in a foreign land, its smell is unique and has penetrating power, making people instantly alert.
The density of this substance is greater than that of water. If it is dumped in water, such as a stone sinking abyss, it goes straight down and is decisively layered with water. The upper water is still clear, and the lower layer is the stable state of the substance. Its boiling point is quite considerable, and it needs a higher temperature to boil it into a gaseous state. Just like to sublimate it, it needs to be tested by fire. The melting point is in a specific low temperature range, and it is easy to condense when cold. It is like water in a cold winter turning into hard ice, and the form changes from flow to solidification.
Furthermore, 1% 2C3-dibromo-5-pentyne has good solubility in organic solvents, like a duck to water. It can be mixed with many organic solvents, and it is seamless and indistinguishable from each other. This solubility is like mixing fine sand into water, which is evenly distributed after stirring, making it difficult to trace.
However, this thing is also dangerous, because it is flammable, in case of open flames and hot topics, it will be like dry firewood in case of fire, instantly exploding, with amazing power. When operating, you need to be very careful, like walking on thin ice in the abyss, you must not take it lightly, so as not to cause a disaster.
What are the synthesis methods of 1,3-dibromo-5-fluorobenzene?
There are several common methods for the synthesis of 1% 2C3-dibromo-5-chlorobenzene:
One is the halogenation reaction method. Benzene can be taken as the starting material first, and under specific reaction conditions, benzene and bromine can be substituted. Because the hydrogen atom on the benzene ring has a certain activity, the bromine atom can replace the hydrogen on the benzene ring in the presence of suitable catalysts such as iron or iron tribromide. Controlling the reaction conditions and the amount of bromine, the bromine atom can be introduced preferentially to the specific position of the benzene ring to obtain a bromobenzene product. Subsequently, by re-halogenating the bromobenzene, by regulating the reaction conditions, the second bromine atom can selectively enter the ortho or meta position to obtain 1,3-dibromobenz Finally, 1,3-dibromo-5-chlorobenzene is obtained by introducing chlorine atoms at the 5th position of 1,3-dibromobenzene with chlorine reagents such as chlorine gas or chlorination agents under appropriate catalyst and reaction conditions.
The second is to use other compounds containing benzene rings as starting materials for conversion. For example, select a specific substituted benzene derivative whose benzene ring already has some transformable groups. First, these groups are converted into bromine atoms through a series of reactions by organic synthesis. This process may involve various reaction steps such as substitution, oxidation, and reduction. After two bromine atoms are successfully introduced into the benzene ring and the positions meet the requirements, chlorine atoms are introduced at the 5th position through a specific reaction. This method requires careful design of the reaction route according to the structure of the starting compound to ensure the selectivity and yield of each step.
The third is the cross-coupling reaction using metal catalysis. First prepare benzene derivatives with bromine atoms and suitable leaving groups, as well as chlorine-containing nucleophiles. Under the action of metal catalysts such as palladium catalysts, the two are cross-coupled. This reaction can achieve the breaking of carbon-halogen bonds and the formation of new carbon-carbon bonds or carbon-halogen bonds under relatively mild conditions. Through rational selection of reaction substrates, catalysts and reaction conditions, bromine atoms can be introduced at the 1,3 positions and chlorine atoms at the 5 positions of the benzene ring to achieve the synthesis of 1,3-dibromo-5-chlorobenzene. This method has the advantages of mild reaction conditions and high selectivity, but the catalyst cost is higher and the reaction operation requirements are stricter.
What are the precautions for storing and transporting 1,3-dibromo-5-fluorobenzene?
1% 2C3-dibromo-5-chlorobenzene requires attention to many matters during storage and transportation.
One is related to storage. This substance should be placed in a cool, dry and well-ventilated place, and must not be close to fire or heat sources to prevent its chemical properties from changing and causing danger due to excessive temperature. Because it has certain chemical activity, high temperature or decomposition reactions. And should be stored separately from oxidants, strong bases, etc., to avoid chemical reactions in contact with them. If the two are mixed, or react violently, it will cause serious consequences such as fire and explosion. The storage place should also be equipped with suitable containment materials. In the event of leakage, it can be collected in time to prevent the spread of pollution.
Second, about transportation. Before transportation, it is necessary to ensure that the packaging is intact. Packaging materials must be able to effectively prevent the leakage and volatilization of the substance. Containers with good sealing performance are commonly used and properly fixed to avoid packaging damage due to bumps and collisions during transportation. During transportation, relevant hazardous chemical transportation regulations must be strictly followed, and transportation vehicles must be equipped with corresponding fire protection equipment and emergency treatment equipment. Escorts also need to be familiar with the characteristics of the substance and emergency disposal methods. In case of emergencies, they can respond quickly and correctly. At the same time, transportation routes should try to avoid densely populated areas and environmentally sensitive areas to prevent leakage from causing serious harm to people and the environment.
What is the approximate market price of 1,3-dibromo-5-fluorobenzene?
The market price of 1% 2C3-dibromo-5-chlorobenzene fluctuates due to a variety of factors, making it difficult to give an exact value.
In the market, the price of this compound is first affected by the cost of raw materials. If the starting material required to synthesize the substance is difficult to obtain and the production is limited, the price increase will drive up the cost of 1% 2C3-dibromo-5-chlorobenzene, which in turn will increase the market price.
The complexity of the production process is also crucial. If the preparation process requires multi-step reactions, special reaction conditions (such as high temperature, high pressure, strict anhydrous and anaerobic environment) or the use of expensive catalysts, the production cost will increase, which will be reflected in higher market prices.
The market supply and demand relationship is also critical. If the demand for 1% 2C3-dibromo-5-chlorobenzene increases sharply during a certain period of time, such as the explosion of demand in the synthesis of some pharmaceutical and pesticide intermediates, and the supply cannot keep up in time, the price will rise; conversely, if the market demand is low and the supply is sufficient, the price may fall.
In addition, the purity of the product has a significant impact on the price. The preparation of high-purity 1% 2C3-dibromo-5-chlorobenzene is difficult and can meet high-end application scenarios, such as for precision chemical synthesis and high-end pharmaceutical research and development, and the price will be much higher than that of ordinary purity products.
Generally speaking, in the chemical raw material market, the price per kilogram of ordinary purity 1% 2C3-dibromo-5-chlorobenzene may range from hundreds to thousands of yuan; if it is a high-purity product that meets the strict standards of a specific industry, the price may be higher. However, the specific price needs to pay attention to the dynamics of the chemical raw material trading market in real time and consult relevant suppliers to know the exact value.