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1,3-Dibromo-5-Fluoro-2-Nitrobenzene

1,3-Dibromo-5-Fluoro-2-Nitrobenzene

Hongda Chemical

Specifications

HS Code

503872

Chemical Formula C6H2Br2FNO2
Molecular Weight 300.9
Appearance Solid (Typical description, actual may vary)
Cas Number Specific CAS number would be needed for accurate entry
Melting Point Data - dependent on purity and experimental conditions
Density Data - requires experimental determination
Solubility In Water Low solubility (Aromatic nitro - halide compounds generally have low water solubility)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (General behavior of aromatic compounds)
Stability Stable under normal conditions, but may react with strong reducing agents or bases

As an accredited 1,3-Dibromo-5-Fluoro-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - dibromo - 5 - fluoro - 2 - nitrobenzene packaged in a sealed chemical - grade bottle.
Storage 1,3 - Dibromo - 5 - fluoro - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly - sealed container to prevent moisture and air exposure. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions.
Shipping 1,3 - Dibromo - 5 - fluoro - 2 - nitrobenzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and secure packaging to prevent leaks during transit.
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1,3-Dibromo-5-Fluoro-2-Nitrobenzene 1,3-Dibromo-5-Fluoro-2-Nitrobenzene
General Information
Historical Development
1,3-Dibromo-5-fluoro-2-nitrobenzene belongs to the genus of chemical substances. Although the historical development of its substances has not been as detailed as it is today, it is also a trace of the evolution of chemical technology. In the past, chemists studied the properties and changes of substances and explored them step by step. Initially, or only theoretically inferred the possibility of this compound, and then as experimental means gradually enriched, they began to get involved in its experimental synthesis. After various attempts, overcoming many difficulties, such as the selection of raw materials and the determination of reaction conditions, it was finally able to obtain a relatively stable system. Although the initial yield was not high, chemists were determined to continue, and through repeated improvement of the process, the synthesis method was increasingly perfected, paving the way for the in-depth study and wide application of this compound in later generations, adding a unique luster to the long river of chemical development.
Product Overview
Today there is a substance called 1,3-dibromo-5-fluoro-2-nitrobenzene. Its shape is also a chemical material, which is quite useful in the field of scientific research. Looking at its structure, bromine, fluorine, and nitro are connected to the benzene ring, and the atoms are arranged in an orderly manner and complement each other.
The properties of this substance are unique due to the characteristics of the atoms. The introduction of bromine atoms increases its reactivity; fluorine atoms also affect its chemical behavior, giving it special properties. The presence of nitro groups makes it unique in specific reactions.
In the process of experimentation, it can be prepared by various methods. Or from benzene derivatives, through halogenation, nitrification and other steps, fine operation, can be prepared. In the process of organic synthesis, it can be a key intermediate to help researchers build complex molecular structures to achieve the purpose of exploring unknown and innovative results.
Physical & Chemical Properties
1,3-Dibromo-5-fluoro-2-nitrobenzene belongs to the genus of chemical substances. Its physical properties, at room temperature, are light yellow in color, if crystalline, pure and stable in nature. The melting point is appropriate, and at a specific temperature, the state changes in an orderly manner. Its density is uniform, with a certain specific gravity. Compared with common solvents, its solubility is different. In a certain type of organic solvent, it is soluble and compatible.
In terms of its chemical properties, due to the coexistence of halogen atoms, nitro and fluorine atoms in the structure, its activity is unique. Nitro has strong electron absorption, causing the electron cloud density of the benzene ring to change, so that the orientation of electrophilic substitution reaction is regular. Halogen atoms can cause a series of nucleophilic substitution changes, fluorine atoms because of their high electronegativity, and add variables to the reaction. All these make this substance widely used in the field of organic synthesis, and it is valued by chemical researchers. It can open up new paths and promote the production of new substances.
Technical Specifications & Labeling
Today there is a product called 1,3-dibromo-5-fluoro-2-nitrobenzene. To clarify its technical specifications and identification (product parameters), it should be reviewed in detail.
Its shape is also, the color is pure and the quality is uniform, this is the logo of the appearance. As for the specifications, the ingredients contained are accurate and few impurities, which are in line with the preparation regulations. The content of 1,3-dibromo-5-fluoro-2-nitrobenzene must reach a high standard to meet various uses.
In terms of identification, on the packaging, the name is clear and the parameters are clear. From its molecular formula, we can know its chemical structure; looking at its molecular weight, we can know its quality. And there are warning words to explain the risk of its nature, so that the user can use it. In this way, the details of technical specifications and labels can make this thing good.
Preparation Method
To prepare 1,3-dibromo-5-fluoro-2-nitrobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First take an appropriate amount of fluorobenzene, use mixed acid (sulfuric acid and nitric acid in a specific ratio) as nitrifying reagent, and slowly add it dropwise in a low temperature environment. This step aims to introduce nitro groups accurately to generate 2-nitrofluorobenzene. After the reaction is completed, the product is purified by washing with water, liquid separation, etc.
Then, 2-nitrofluorobenzene is mixed with liquid bromine, and the bromination reaction occurs under heating conditions with iron or iron tribromide as catalyst. Bromine molecules polarize under the action of the catalyst and attack a specific position of the benzene ring to obtain the crude product of 1,3-dibromo-5-fluoro-2-nitrobenzene. It is further purified by distillation, recrystallization and other means to achieve the desired purity. In this process, the temperature, reagent dosage and reaction time need to be carefully controlled to obtain satisfactory yield and purity.
Chemical Reactions & Modifications
I have tried to study chemical substances, especially in 1,3-dibromo-5-fluoro-2-nitrobenzene. The chemical reaction of this compound is related to its qualitative change, which cannot be ignored.
The method of the past, the reaction is also often discordant. Or the yield is not as satisfactory, or the by-products are plentiful, resulting in impure quality. We devote ourselves to our research, and we want to change the good method.
is a detailed study of the classics, referred to the theory of Fang family, and practiced in the laboratory. After repeated trials and errors, the influence of temperature, solvent, catalyst and other factors is observed. In the end, the conditions of the reaction were adjusted, the ratio of the reactants was appropriate, the temperature control was accurate, and the good agent was selected as the catalyst.
As a result, the reaction of 1,3-dibromo-5-fluoro-2-nitrobenzene gradually became better, the yield was improved, and the quality was also improved. Although there are still improvements, it has paved the way for future research, and it can be expected to be improved in the future.
Synonyms & Product Names
1,3-Dibromo-5-fluoro-2-nitrobenzene, which is quite unique in my chemical research. Its aliases and trade names are also interesting. Looking at the ancient books of the past, the names of chemical substances often vary from time to time, place, and person. The same substance has many names.
1,3-dibromo-5-fluoro-2-nitrobenzene, or those who call it another name. These different names are all derived from the evolution of chemical research. When scholars from all over the world communicate, due to differences in habits and cognition, many aliases have emerged. The determination of a trade name is also related to various factors such as market and use. Either because of its characteristics or because of its use, it is named as a unique commodity.
Today, when we study this thing, we should clarify its many terms in order to be accurate and not confused among the vast chemical literature and market transactions. In this way, it will contribute to the improvement of chemical research and the expansion of product applications.
Safety & Operational Standards
Safety and Operation Specifications for 1,3-Dibromo-5-fluoro-2-nitrobenzene
F 1,3-dibromo-5-fluoro-2-nitrobenzene is an important substance in chemical research. Its unique nature is related to the safety and effectiveness of the experiment. Therefore, those who operate it should not be careless. Follow the following norms.
#1. Storage
This substance should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight to prevent its properties from mutating due to light. It is advisable to keep away from fire and heat sources, or cover them with flammable and explosive risks. Where stored, corresponding fire fighting equipment and leakage emergency treatment equipment should be prepared. And it needs to be stored separately from oxidants, reducing agents, acids, alkalis, etc., and must not be mixed to prevent dangerous chemical reactions.
#2. Rules of Operation
When operating, it must be carried out in a fume hood to ensure the safety of the experimenter's breathing and prevent its volatile gas from invading the human body. The experimenter can protect his eyes from splashing when wearing appropriate protective equipment, such as protective glasses; wear chemically resistant gloves to prevent burns caused by contact with the skin; wear protective clothing to completely block contact with the body. During the operation, the movement should be steady and slow to avoid leakage or accidents caused by violent shaking or collision. If there is a substance spilled, do not panic, should be dealt with immediately according to the established emergency procedures. First evacuate unrelated personnel, then cover the adsorption with appropriate materials, carefully collect, properly dispose of, must not be discarded at will, so as not to pollute the environment.
#3. Emergency measures
In case of accidental contact with the skin, you should immediately rinse with a large amount of flowing water for at least fifteen minutes, and then seek medical treatment. If it enters the eye, you must also quickly rinse with a large amount of water, blink while flushing, and then go to the ophthalmology department for treatment. If you inhale accidentally, you should immediately move to a fresh air place to keep the respiratory tract unobstructed. If you have shortness of breath or difficulty, you need to perform artificial respiration immediately and rush to the hospital.
Chemical research, safety first. In the operation of 1,3-dibromo-5-fluoro-2-nitrobenzene, strict adherence to safety and operating standards can achieve the purpose of research, ensure the well-being of personnel, and protect the cleanliness of the environment.
Application Area
Today, there is a thing named 1,3-dibromo-5-fluoro-2-nitrobenzene, which is quite wonderful in various application fields. In the field of pharmaceutical research and development, this compound can be used as a key intermediate, helping to achieve the precise effect of medicine, and contributing to the healing of diseases.
In the field of materials science, it can be applied to the synthesis of special materials, making the material have extraordinary characteristics, or increasing its toughness, or endowing it with unique optical properties to meet diverse needs.
In the field of agricultural chemistry, it can also emerge. Through ingenious creation, it can become an efficient pesticide, protect crops from pests and diseases, and ensure the harvest of five grains. This 1,3-dibromo-5-fluoro-2-nitrobenzene, in many application fields, has shown its extraordinary use, such as pearl shining, for the development of various industries, making great contributions.
Research & Development
In recent years, I have been known for chemical substances, such as 1,3-dibromo-5-fluoro-2-nitrobenzene. This substance is also unique in its properties and has a wide range of uses.
At the beginning of my research, I felt that its synthesis method was very promising. Then I dedicated myself to my research and read the classics to find the best way. In the experimental room, I tried repeatedly to observe the influence of temperature, pressure, and the ratio of reagents on its yield.
After several years, I have made some gains. Optimize the synthesis method to make the yield gradually increase. However, it is still not enough to think about the expansion of its application. Looking at today's world, the fields of electronics and medicine are developing rapidly, and this substance may emerge in it.
We are discussing with colleagues to explore the possibility of its application in new fields. After many studies and experiments, we have achieved some results. It has potential in the preparation of new electronic materials and the synthesis of specific drug intermediates.
We should continue to forge ahead and make unremitting research, hoping to make 1,3-dibromo-5-fluoro-2-nitrobenzene shine in the process of scientific research and industry, and contribute to the development of chemistry.
Toxicity Research
1,3-Dibromo-5-fluoro-2-nitrobenzene is also a chemical substance. It is crucial for toxicological research. The analysis of its toxicity is related to the safety of all living beings and the tranquility of the environment.
Looking at the structure of this compound, the functional groups of bromine, fluorine and nitro are concentrated in the benzene ring. Nitro, which is often highly oxidizing and toxic, can disturb the biochemical reactions in organisms and cause cell damage. The presence of bromine and fluorine atoms also changes their physicochemical properties, increases their fat solubility, and is easy to enter the body of organisms.
Tested in animals, or causes damage to organs, such as changes in liver and kidney function. Entering the environment, through the food chain, it is involved in high-rise organisms and endangers the ecological balance. Therefore, the study of the toxicity of this 1,3-dibromo-5-fluoro-2-nitrobenzene must be cautious and its harm must be analyzed in detail, so as to prevent the basis and ensure the safety of all things.
Future Prospects
In the future, the research of 1,3-dibromo-5-fluoro-2-nitrobenzene is of great importance to our researchers. Its unique characteristics, including bromine, fluorine, and nitro groups, are unique in nature and limited in potential.
In the field of synthesis, we hope to develop more effective methods to improve its efficiency and reduce its cost. Make the synthesis process more convenient, efficient, and harmless. It is not possible to expand the synthesis path by leveraging new technologies, such as fluidization, photocatalytic reaction, etc.
In terms of application, it may be useful for research and development. Or it can be used in new technologies to assist in the research of special effects and solve the dilemma of many diseases. It is also expected to show its skills in the materials department, and the new properties of materials can be used in materials, light, etc.

Of course, 1,3-dibromo-5-fluoro-2-nitrobenzene will be developed, which is bright and promising, waiting for our chemical researchers to unremitting exploration.
Where to Buy 1,3-Dibromo-5-Fluoro-2-Nitrobenzene in China?
As a trusted 1,3-Dibromo-5-Fluoro-2-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dibromo-5-Fluoro-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1,3-dibromo-5-fluoro-2-nitrobenzene?
1% 2C3-dibromo-5-pentene-2-carbonylbenzene is an organic compound, and its physical properties are as follows:
This substance is mostly crystalline solid under normal conditions, and its quality is relatively brittle. The melting point is in a specific temperature range, and its melting point value can be known through precise experimental determination. This characteristic is of great significance for the identification and purification of this substance. Because its melting point is relatively fixed, it can be distinguished from other analogs.
Looking at its color, pure 1% 2C3-dibromo-5-pentene-2-carbonyl benzene often appears white or almost white, but if it contains impurities, the color may change, from yellowish to darker tones are possible.
Smell, the compound has a special smell, this smell is unique, although it is difficult to describe accurately, but it is an intuitive way to identify it, but because it may be irritating, it needs to be handled with caution when smelling. In terms of solubility, in common organic solvents, it exhibits good solubility in some organic solvents such as dichloromethane and chloroform, and can be miscible with these solvents in a certain proportion. This property is extremely critical in the organic synthesis reaction and separation process, and its solubility can be used to achieve the extraction, separation and reaction medium selection of substances. In water, its solubility is poor and almost insoluble, which is due to the fact that its molecular structure contains fewer hydrophilic groups and a large proportion of hydrophobic parts, making it difficult to form effective interactions with water molecules.
In addition, the density of 1% 2C3-dibromo-5-pentene-2-carbonylbenzene is also an important physical property. Compared with water, its density is higher. When it comes to liquid-liquid separation and other operations, this property can be used to judge its phase distribution in the mixed system.
What are the main uses of 1,3-dibromo-5-fluoro-2-nitrobenzene?
1% 2C3-dibromo-5-pentene-2-carbonyl naphthalene, which has important uses in many fields.
In the field of medicinal chemistry, it is often a key intermediate in the synthesis of characteristic drugs. Due to its unique chemical structure, it can construct structures similar to bioactive molecules through specific reactions, helping to develop antibacterial, antiviral and even anticancer drugs. For example, in the development of some new anti-cancer drugs, this is used as a starting material to obtain compounds with activity targeting tumor cells through multi-step reactions, opening up new avenues for the development of cancer therapeutic drugs.
In the field of materials science, it can be used to prepare functional polymer materials. By ingeniously designing the polymerization reaction, 1% 2C3-dibromo-5-pentene-2-carbonyl naphthalene is introduced into the polymer chain segment, giving the material unique optical and electrical properties such as. For example, new photoelectric materials synthesized, due to the presence of this compound, exhibit excellent luminous efficiency and stability in optoelectronic devices such as organic Light Emitting Diodes (OLEDs), promoting the development of display technology.
It is an extremely important synthetic building block in the field of organic synthetic chemistry. With its multiple reactivity check points, chemists can carry out diverse organic reactions, such as nucleophilic substitution, addition reactions, etc., for the construction of complex and novel organic molecules. For example, in the total synthesis of natural products, it is introduced as a key link to help achieve the efficient synthesis of target natural products and provide a powerful tool for the study of natural product chemistry.
What is the synthesis method of 1,3-dibromo-5-fluoro-2-nitrobenzene?
The method of synthesis of 1% 2C3-dibromo-5-pentene-2-carbonyl indole can follow the following steps.
First, indole is used as the starting material, and the nitrogen atom of indole is reacted with appropriate acylating reagents through acylation. Acylating reagents can be selected from acetyl chloride, acetic anhydride, etc. Under suitable reaction conditions, such as in inert solvents (such as dichloromethane, chloroform, etc.), organic bases (such as triethylamine, pyridine, etc.) are used as acid binding agents, and the temperature is moderately controlled to fully react. The corresponding acyl indole derivatives can be obtained.
Then, the resulting acyl indole derivative is enylated. Select a suitable enylation reagent, such as allyl halide (allyl bromide, allyl chloride, etc.), under alkaline conditions, often use potassium carbonate, sodium carbonate and other inorganic bases in polar solvents (such as N, N-dimethylformamide, dimethylsulfoxide, etc.), heat and stir to introduce the alkenyl group into the specific position of the acyl indole to obtain the acyl indole intermediate containing the alkenyl group.
Bromination reaction is carried out again. Take the above intermediates and use brominating reagents, such as liquid bromine, N-bromosuccinimide (NBS), etc., in an appropriate reaction system, such as carbon tetrachloride, dichloromethane, etc., in the presence of light or initiators (such as benzoyl peroxide), the bromine atom is selectively added to the alkenyl group and other suitable reaction check points to generate 1% 2C3-dibromo-5-pentene-2-carbonyl indole product.
After the reaction is completed, regular separation and purification methods, such as extraction, column chromatography, etc., can obtain a pure target product. The whole synthesis process requires fine regulation of reaction conditions and attention to the selectivity and yield of each step in order to achieve optimum results.
What should I pay attention to when storing and transporting 1,3-dibromo-5-fluoro-2-nitrobenzene?
1% 2C3-dibromo-5-pentene-2-ketonaphthalene is a special chemical substance. When storing and transporting, many matters must be paid attention to.
First environmental conditions. The place of storage must be cool and dry. This may be sensitive to temperature and humidity, high temperature and humid environment, which can easily cause chemical changes and affect quality. If it is placed in a hot and humid place, or causes decomposition, deterioration, etc., it will damage its inherent characteristics.
Second is packaging. Packaging must be tight and suitable. Containers of specific materials should be used to prevent leakage. If a glass or special plastic container with good sealing performance is used, ensure that the substance is effectively isolated from the external environment. Otherwise, once it leaks, it will not only waste materials, but also cause pollution to the surrounding environment, and even endanger the safety of personnel.
Furthermore, during transportation, shock and collision prevention cannot be ignored. Because of its certain sensitivity, bumps and vibrations during transportation may cause unexpected reactions. Therefore, there must be appropriate buffering devices in the transportation vehicle to firmly place the goods and avoid collisions.
In addition, during storage and transportation, it should be kept away from fire sources, heat sources and strong oxidants. This substance may be flammable or easily react violently with oxidants, causing serious accidents such as fire and explosion. Fireworks are strictly prohibited around warehouses and transportation vehicles, and dangerous goods such as oxidizers cannot be mixed with them.
In addition, relevant operators need to be professionally trained and familiar with the characteristics and safe operation procedures of the substance. Handle with care when handling to avoid package damage due to improper operation.
In this way, it can ensure safety and maintain its quality and performance during the storage and transportation of 1% 2C3-dibromo-5-pentene-2-ketonaphthalene.
What are the effects of 1,3-dibromo-5-fluoro-2-nitrobenzene on the environment and the human body?
1% 2C3-dibromo-5-chloro-2-fluorophenyl has a multifaceted impact on the environment and human body, as detailed below:
Impact on the environment
1. ** Soil pollution **: If this substance enters the soil, it is difficult to be rapidly decomposed by soil microorganisms due to its stable chemical structure, and will gradually accumulate in the soil. Over time, it will change the physical and chemical properties of the soil, affect the balance and circulation of nutrients in the soil, and then hinder the growth and development of plant roots, reduce the ability of plants to absorb nutrients and water, lead to poor growth of vegetation, and even cause changes in the structure of vegetation communities.
2. ** Water pollution **: Once it flows into the water body, it will cause harm to the aquatic ecosystem. It may interfere with the physiological functions of aquatic organisms, and cause damage to the nervous system and reproductive system of aquatic animals such as fish and shellfish. For example, it may affect the behavior patterns of fish, reducing their ability to avoid natural enemies and find food; it may also cause reproductive obstacles for aquatic organisms, resulting in a decrease in population and destroying the balance of aquatic ecosystems.
3. ** Air pollution **: Under specific conditions, such as high temperature or combustion process, the substance may evaporate into the atmosphere, participate in atmospheric chemical reactions, and have an impact on air quality. It may react with other pollutants in the atmosphere to generate secondary pollutants, further aggravate the degree of air pollution, and affect the quality and stability of the atmospheric environment.
Effects on the human body
1. ** Nervous system **: This substance has certain neurotoxicity. After entering the human body, it may reach the nervous system through blood circulation. Interferes with the transmission process of neurotransmitters, affects the normal conduction of nerve signals, and then causes symptoms such as headache, dizziness, fatigue, and memory loss. Long-term exposure may cause more serious and irreversible damage to the nervous system.
2. ** Reproductive system **: Potential harm to the human reproductive system. May interfere with the normal function of the endocrine system, affect the synthesis, secretion and regulation of hormones. If it affects the balance of sex hormones, it interferes with the production, development and maturation of germ cells, thereby reducing fertility and even increasing the risk of reproductive health problems such as fetal malformations and miscarriages.
3. ** Immune System **: It will weaken the function of the human immune system. Reducing the activity and number of immune cells makes the body less able to resist the invasion of external pathogens, resulting in the body being more susceptible to infections by pathogens such as bacteria and viruses, increasing the chance of disease, and the recovery process after disease may be slower.