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1,3-Dibromo-5-Fluoro-2-Iodobenzene

1,3-Dibromo-5-Fluoro-2-Iodobenzene

Hongda Chemical

Specifications

HS Code

275966

Name 1,3 - Dibromo - 5 - Fluoro - 2 - Iodobenzene
Molecular Formula C6H2Br2FI
Molecular Weight 344.79
Appearance Solid (Typical)
Boiling Point N/A (depends on conditions, usually requires experimental determination)
Melting Point N/A (usually needs experimental measurement)
Density N/A (experimental value)
Solubility In Water Insoluble (organic halogenated aromatic compound, typically hydrophobic)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (general behavior for aromatic halides)
Purity Varies by manufacturer (ideally high - purity for most applications)

As an accredited 1,3-Dibromo-5-Fluoro-2-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,3 - dibromo - 5 - fluoro - 2 - iodobenzene in a sealed chemical - grade bottle.
Storage 1,3 - dibromo - 5 - fluoro - 2 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly - sealed container to prevent vapor leakage. Due to its chemical nature, store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping 1,3 - dibromo - 5 - fluoro - 2 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring safe transportation to prevent leakage and environmental risks.
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1,3-Dibromo-5-Fluoro-2-Iodobenzene 1,3-Dibromo-5-Fluoro-2-Iodobenzene
General Information
Historical Development
1,3-Dibromo-5-fluoro-2-iodobenzene, the origin of this substance can be traced back to the beginning of chemical exploration in the past. At that time, various chemical talents, in the laboratory, worked hard to explore the mysteries of various compounds.
At first, the research on halogenated aromatic hydrocarbons was only hazy knowledge. People gradually discovered that halogen substituents can cause changes in the properties of benzene rings. After years of research, the experimental conditions have become more accurate and the synthesis methods have become more and more perfect.
First, similar simple halogenated benzene derivatives were synthesized, and then expanded to polyhalogenated compounds containing special atoms. The synthesis of 1,3-dibromo-5-fluoro-2-iodobenzene is the crystallization of the wisdom and hard work of many chemists. From simple equipment to precision instruments; from ignorant attempts to system theory guidance, its research and development process has witnessed the vigorous development of the chemical field.
Product Overview
Today, there is a substance named 1,3-dibromo-5-fluoro-2-iodobenzene. It is an organic halide with a unique structure. In this compound, bromine, fluorine, and iodine atoms are cleverly connected to the benzene ring. The benzene ring is inherently stable, but the substitution of the trihalogen atom makes its chemical properties unique.
The bromine atom is active and can be used as a leaving group in many reactions to attract other groups. The fluorine atom has strong electronegativity, which can change the polarity of molecules and the distribution of electron clouds, which affects the reactivity. The iodine atom is relatively large, and the steric resistance effect is obvious, which also affects the direction of the reaction.
1,3-dibromo-5-fluoro-2-iodobenzene has great potential in the field of organic synthesis, or as an intermediate for the preparation of special functional materials and pharmaceuticals, helping chemical research to move towards a new frontier.
Physical & Chemical Properties
1,3-Dibromo-5-fluoro-2-iodobenzene is also a chemical substance. Its physical and chemical properties are crucial to our research. Looking at its physical properties, at room temperature, the color state is clear, or it is solid, and it has a specific melting and boiling point. As for the chemical properties, the atoms of bromine, fluorine, iodine and other atoms in its structure give it unique reactivity. Bromine atoms are active and can participate in many substitution reactions under suitable conditions, meet nucleophiles, or generate new compounds. Fluorine atoms have strong electronegativity, which affects the polarity of molecules, making the substance show a different trend in chemical reactions. Iodine atoms are not idle either. Their unique electron cloud structure adds variables to the reaction process. Studying the physical and chemical properties of this substance, such as exploring the subtle path, can help us understand its potential uses in chemical synthesis, materials science and other fields, paving the way for scientific progress.
Technical Specifications & Labeling
1,3-Dibromo-5-fluoro-2-iodobenzene is a kind of chemical substance. Its process specifications and identification (product parameters) are related to the quality and characteristics of this substance. For process specifications, the preparation method must be carefully reviewed. From the selection of raw materials, the essential quality is pure and free of impurities, and the temperature, pressure, and time are controlled according to the specific order. If synthesized by a certain method, a reactant should be reacted at a suitable temperature to achieve the expected transformation. In terms of identification (product parameters), the appearance should have a specific color state, the purity must be extremely high, and the impurity content must be minimal. Physical parameters such as melting point and boiling point must also be accurately determined to meet the established standards. In this way, high-quality 1,3-dibromo-5-fluoro-2-iodobenzene products are obtained, which are suitable for use in various fields of chemical industry.
Preparation Method
To prepare 1,3-dibromo-5-fluoro-2-iodobenzene, the raw materials and production process, reaction steps and catalytic mechanism are the key. First take an appropriate amount of fluorobenzene-containing compounds as the base material, which is the starting material of the reaction. In a specific ratio, add a brominating reagent, such as liquid bromine, and add a suitable catalyst, preferably iron tribromide, in a reaction kettle with precise temperature control, so that the bromination reaction can occur in an orderly manner. After the bromination is completed, then introduce an iodizing reagent, such as potassium iodide, and use suitable solvents and catalytic conditions to allow the iodization reaction to proceed smoothly. This is the second step. This two-step reaction requires fine control of temperature, time, and the proportion of reactants to ensure that each step is complete and there are few side reactions. The catalytic mechanism is that the catalyst can effectively reduce the activation energy of the reaction and speed up the reaction rate, so that the product of 1,3-dibromo-5-fluoro-2-iodobenzene can be obtained.
Chemical Reactions & Modifications
Today there is a substance called 1,3-dibromo-5-fluoro-2-iodobenzene. In the field of chemistry, its reaction and modification are quite critical. This compound, with bromine, fluorine and iodine atoms coexisting on a benzene ring, has unique characteristics.
Its chemical reaction often varies depending on the activity of each atom. Although both bromine and iodine have certain nucleophilic substitution activity, the atomic radius of iodine is large, and the electron cloud is easily polarized. In some nucleophilic substitution reactions, it may be easier to leave. Fluorine atoms have strong electronegativity, which can affect the density distribution of electron clouds in the benzene ring, and reduce the density of adjacent and para-site electron clouds, making it difficult for electrophilic substitution reactions to occur at this site.
To modify this compound, a nucleophilic substitution reaction can be used to replace bromine or iodine atoms with specific nucleophilic reagents, introduce new functional groups, and endow it with different chemical properties, such as changing solubility and reactivity. It may be of great use in fields such as organic synthesis and material chemistry.
Synonyms & Product Names
I have heard that there is a product named 1,3-dibromo-5-fluoro-2-iodobenzene. This is a chemical product and is also used in the academic world. Its synonyms and trade names are also investigated by us.
The synonyms of husband are other names that characterize this product. Although the names are different, they are actually the same. The trade name is the name established by the merchant for selling this product.
In my research, I have investigated the characteristics and preparation methods of this product in detail, as well as its synonyms and trade names. Or called by other words, they all refer to this 1,3-dibromo-5-fluoro-2-iodobenzene. We are studying, hoping to understand its various terms, so that the academic community to communicate more smoothly, its application and promotion, is also beneficial. Hope to be able to use synonyms and trade names to help people better understand this thing, in the way of chemistry, add bricks and mortar.
Safety & Operational Standards
In the case of 1,3-dibromo-5-fluoro-2-iodobenzene, chemical substances are also involved. It is of paramount importance in terms of its safety and operating practices.
This substance has certain chemical activity, and the following procedures must be followed during operation. The operator should wear appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent skin and eye contact. When working in a well-ventilated place, if in a closed space, harmful gases may accumulate, which may cause poisoning.
When storing, it should be placed in a cool, dry and ventilated place, away from fire, heat and oxidants. Due to its active chemical properties, it is easy to cause dangerous chemical reactions when exposed to heat or oxidants.
If you accidentally come into contact with this substance, if you touch your skin, rinse it with a lot of water immediately, followed by soap; if it enters your eyes, rinse it with flowing water or normal saline immediately, and seek medical attention immediately. If you inhale its volatile gas, quickly move to a fresh place in the air. If you feel uncomfortable breathing, you need to seek medical attention immediately.
Furthermore, during operation, the utensils used must be clean and dry to prevent impurities from affecting its quality and stability. After the experiment is completed, properly dispose of the remaining materials, and do not discard them at will. Do it according to the norms of chemical waste treatment to avoid polluting the environment.
In this way, strict adherence to safety and operating standards can ensure the safety of personnel and the smooth operation of the experiment.
Application Area
1,3-Dibromo-5-fluoro-2-iodobenzene is also an organic compound. It has a wide range of uses and is often a key intermediate in the synthesis of special drugs in the field of medicinal chemistry. Due to its unique chemical structure, it can construct molecular structures with specific pharmacological activities through delicate chemical reactions, helping to create new drugs to treat various diseases.
In the field of materials science, it also shows important value. Or it can participate in the synthesis of materials with special optical and electrical properties, such as those used in advanced optoelectronic devices, to help them achieve better performance and improve the efficiency and stability of optoelectronic devices.
In organic synthesis chemistry, it is an important building block for the synthesis of complex organic molecules. Chemists use their special substituent positions and properties to ingeniously design reaction routes, expand the structural diversity of organic compounds, and promote the progress and development of organic synthetic chemistry.
Research & Development
Today, there is a compound named 1,3-dibromo-5-fluoro-2-iodobenzene. As a chemical researcher, I have been dedicated to studying this substance for a long time.
Looking at its structure, the atoms of bromine, fluorine and iodine are cleverly connected, giving it unique properties. In the process of research, explore the method of its synthesis, and try to adjust the conditions of the reaction after hundreds of attempts, hoping to improve the yield and purity.
This compound has potential applications in materials science, pharmaceutical research and development and other fields. After unremitting research, some of its characteristics and reaction laws have been understood. However, in order to make it widely used, it still needs to be further explored.
Our generation should continue to study this object with diligence, hoping to expand its application scope, promote the progress of science, and seek the well-being of future generations. In the process of chemical research, we should make unremitting progress to reach a higher level.
Toxicity Research
There is a substance today, called 1,3-dibromo-5-fluoro-2-iodobenzene. We focus on toxicity research to investigate its properties in detail. This substance has a unique structure, with bromine, fluorine, and iodine atoms combined in the benzene ring. Or because of its halogen atom, it has potential toxicity.
After various experiments, observe its impact on organisms. Take mice as an experiment, feed them food containing this substance, and observe the changes in their behavior and physiology. At first, the mice's activity decreased slightly, and then their diet gradually became sparse. Organ tests showed signs of damage to the liver and kidneys. Cell experiments also showed that this substance can disturb the normal metabolism of cells, resulting in a decrease in cell viability and an increase in apoptosis.
From this point of view, the toxicity of 1,3-dibromo-5-fluoro-2-iodobenzene cannot be underestimated. During production and use, strict protective measures should be taken to avoid its harm and life, and to ensure the safety of the environment.
Future Prospects
I look at today's world, and chemistry is improving with each passing day. Among many compounds, 1,3-dibromo-5-fluoro-2-iodobenzene is a promising product.
This product has a unique structure, and its ingenious arrangement of bromine, fluorine and iodine atoms gives it specific chemical properties. Looking at the future, it is expected to shine in the field of pharmaceutical research and development. Or it can be used as a key intermediate to help create new types of special drugs, overcome difficult diseases, and seek well-being for the common people.
Or it has emerged in the field of materials science. After ingenious design and synthesis, materials with special photoelectric properties have been prepared, which can be used in advanced electronic equipment and lead the new trend of science and technology. Its future development is as bright as the stars and has a bright future, which is full of longing and waiting to see its brilliant achievements.
Where to Buy 1,3-Dibromo-5-Fluoro-2-Iodobenzene in China?
As a trusted 1,3-Dibromo-5-Fluoro-2-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dibromo-5-Fluoro-2-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-dibromo-5-fluoro-2-iodobenzene?
1,3-Dibromo-5-chloro-2-iodobenzene is an important organic synthesis intermediate, which has key uses in medicine, pesticides, materials and other fields.
In the field of medicine, as a key intermediate, it can be used to synthesize many specific drugs. For example, in the development of anti-tumor drugs, using this as the starting material, through specific chemical reactions, molecules with unique structures and biological activities can be constructed. These molecules may act precisely on specific targets of tumor cells, inhibit tumor cell proliferation, and provide new opportunities for cancer treatment. For example, in the synthesis of antibacterial drugs, 1,3-dibromo-5-chloro-2-iodobenzene participates in the reaction, which can endow the drug with unique antibacterial properties and enhance its ability to inhibit and kill specific bacteria.
In the field of pesticides, its role is also indispensable. It can be used to create new and efficient pesticides. For example, by reacting with other organic compounds, pesticides with high selectivity, low toxicity and environmental friendliness are synthesized. These pesticides have strong killing power against pests, but have little impact on beneficial insects and the environment, which helps to achieve sustainable agricultural development. For example, for common crop pests, the synthetic pesticides can precisely act on the nervous system or physiological metabolic pathways of pests, effectively control pests, and ensure crop yield and quality.
In the field of materials, 1,3-dibromo-5-chloro-2-iodobenzene can be used to prepare functional materials. For example, in the synthesis of organic optoelectronic materials, its participation in the reaction can regulate the photoelectric properties of materials. With the help of rational molecular design and reaction conditions control, materials with excellent luminescence properties or charge transport properties can be prepared, which can be used in organic Light Emitting Diodes (OLEDs), solar cells and other fields. In OLEDs, such materials may improve luminous efficiency and device stability, and promote the development of display technology; in solar cells, they may improve photoelectric conversion efficiency and promote renewable energy utilization.
What are the synthesis methods of 1,3-dibromo-5-fluoro-2-iodobenzene?
The synthesis method of 1% 2C3-dibromo-5-pentene-2-one can be prepared according to the ancient method.
First, pentenone is used as the base, supplemented by a brominating agent, and the bromination reaction is carried out in a suitable environment. Brominating agents, such as liquid bromine, N-bromosuccinimide (NBS), etc. If liquid bromine is used, the dosage and reaction temperature must be carefully controlled to avoid excessive bromination. During the reaction, it is suitable to slowly add liquid bromine dropwise to the solution of pentenone at low temperature, and dissolve it in an inert solvent, such as dichloromethane, carbon tetrachloride, etc. At the same time, appropriate catalysts, such as Lewis acids, can promote the reaction and increase the yield.
Second, start with the corresponding alcohols. First, the pentene-2-ol is oxidized to pentene-2-one. The oxidizing agent can be selected from potassium dichromate-sulfuric acid system, PCC (pyridinium chlorochromate salt), etc. After obtaining pentene-2-one, bromine atoms are introduced as described above to form 1% 2C3-dibromo-5-pentene-2-one.
Or, start with halogenated hydrocarbons. Select an appropriate halogenated pentene and introduce a carbonyl group through a nucleophilic substitution reaction. Commonly used nucleophilic reagents, such as enolates of ethyl acetoacetate, etc., through a series of steps such as hydrolysis and decarboxylation, pentene-2-one is obtained first, and then brominated to obtain the target product.
When synthesizing, all conditions must be strictly controlled. The reaction temperature, time, and the proportion of reactants are all related to the quality and quantity of the product. And after each step of the reaction, the product should be refined by suitable methods, such as distillation, column chromatography, etc., and its impurities can be removed to obtain pure 1% 2C3-dibromo-5-pentene-2-one.
What are the physical properties of 1,3-dibromo-5-fluoro-2-iodobenzene?
1% 2C3-dibromo-5-chloro-2-fluorobenzene is an organic halide. Its physical properties are as follows:
- ** Appearance and Properties **: Normally, it is mostly colorless to light yellow liquid or solid, depending on its purity and the ambient temperature. This compound is formed by different halogen atoms replacing hydrogen atoms on the benzene ring, and its structure causes its appearance to exhibit a specific physical state.
- ** Melting Boiling Point **: Due to the presence of halogen atoms between molecules, the electronegativity of halogen atoms is large, which enhances the intermolecular force, especially the presence of halogen atoms with relatively large atomic masses such as bromine and chlorine, so its melting boiling point is relatively high. However, the exact melting boiling point value will vary due to impurities, molecular space arrangement and other factors. Generally speaking, the melting point may be in the range of tens of degrees Celsius, and the boiling point may be in the hundreds of degrees Celsius.
- ** Solubility **: It is a non-polar or weakly polar organic compound. According to the principle of "similar miscibility", it exhibits good solubility in non-polar or weakly polar organic solvents, such as benzene, toluene, dichloromethane, etc.; while in highly polar water, the solubility is poor. This is due to the formation of hydrogen bonds between water molecules and the tight structure. Non-polar 1% 2C3-dibromo-5-chloro-2-fluorobenzene is difficult to destroy its structure and mix with it.
- ** Density **: Due to the large relative atomic weight of halogen atoms, the density of this compound is greater than that of common organic solvents and water. The halogen atoms inside the molecule occupy a certain space, resulting in an increase in mass per unit volume. In chemical operations or research, this property is crucial for separation, extraction and other links.
What are the precautions for storing and transporting 1,3-dibromo-5-fluoro-2-iodobenzene?
1% 2C3-dibromo-5-pentene-2-one is an organic compound. When storing and transporting, the following matters must be paid attention to:
** Storage **:
First, because of its chemical activity, it should be stored in a cool and well-ventilated place. Extreme heat can easily cause its chemical reactivity to intensify, or cause adverse reactions such as decomposition and polymerization. As "Tiangong Kaiwu" said: "The storage of things should be allowed to go with its own nature, and it should be kept cool and protected from heat." If it is placed in a high temperature place, the quality of Juhe seedlings will be damaged when exposed to the hot sun.
Second, it needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. This is because of its active chemical properties, contact with the above substances can easily trigger violent chemical reactions, such as combustion, explosion, etc. Just like water and fire are incompatible, things of different properties should not be mixed.
Third, the storage container must be tightly sealed. This compound may be sensitive to air and moisture, and the seal can prevent it from deteriorating in contact with air and moisture. It is like a strong city wall to guard against external threats.
Fourth, the storage area should be equipped with suitable materials to contain leaks. In case of leakage, it can be dealt with in time to avoid causing greater harm.
** Transportation **:
First, the transportation vehicle must ensure that the vehicle is in good condition and has corresponding fire and explosion-proof safety facilities. Because of its potential danger, it is necessary to be in the abyss and walking on thin ice during transportation to prevent sparks, hot topics, etc. from causing danger.
Second, it is necessary to prevent it from being heated and damp during transportation. On the road, the weather is changeable, and it is necessary to be properly protected from the influence of the external environment.
Third, when loading and unloading, it should be handled with care, and it is strictly forbidden to drop and heavy pressure. The structure of this compound may be relatively fragile, and rough loading and unloading can easily cause packaging damage and cause leakage. Just as "Tiangong Kaiwu" mentioned the caution of handling utensils, the same should be done with this chemical.
Fourth, transportation personnel must be professionally trained to be familiar with the dangerous characteristics of the compound and emergency treatment methods. Only in this way can they respond calmly and avoid danger in the face of emergencies.
What is the market price range for 1,3-dibromo-5-fluoro-2-iodobenzene?
What you are asking about is the market price range of 1,3-dibromo-5-chloro-2-fluorobenzene. However, the price of this product cannot be hidden in a single word, and it is affected by many factors.
The first to bear the brunt is the price of raw materials. If the price of the raw materials required for the preparation of this compound is high and fluctuates frequently, the price of the finished product will also fluctuate accordingly. For example, if the raw materials are scarce, or the supply is insufficient due to weather, geographical location, or man-made reasons, the price will rise.
Second, the difficulty of the process is also related to the price. If the preparation method is complicated, requires exquisite equipment, superb skills, and is accompanied by many intermediate steps, which consumes a lot of manpower and material resources, the cost will be high and the price will be high.
Furthermore, the state of market supply and demand is the key. If there are many people seeking, but there are few producers, and the supply is in short supply, the price will be high; conversely, if there is excess capacity, the demand is small, and the supply exceeds the demand, the price will be lower.
In addition, regional differences also affect the price. In different places, the price varies due to different transportation costs, tax policies, and market competition.
Generally speaking, in the current market, the price range of 1,3-dibromo-5-chloro-2-fluorobenzene, or due to the above factors, ranges from a few hundred to several thousand yuan per kilogram. However, this is only a rough estimate. The actual price depends on factors such as the time, place and volume of the transaction. At the time of transaction, the exact price can only be known when you carefully observe market dynamics and inquire from multiple parties.