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1,3-Dibromo-2-Fluorobenzene

1,3-Dibromo-2-Fluorobenzene

Hongda Chemical

Specifications

HS Code

889480

Chemical Formula C6H3Br2F
Molar Mass 255.894 g/mol
Appearance Liquid (usually)
Boiling Point Around 230 - 235 °C
Density Approx. 2.08 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low at room temperature
Odor Pungent (characteristic halogenated benzene odor)

As an accredited 1,3-Dibromo-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 1,3 - dibromo - 2 - fluorobenzene packaged in a sealed glass bottle.
Storage 1,3 - dibromo - 2 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions.
Shipping 1,3 - dibromo - 2 - fluorobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit as it's a chemical. It follows strict hazardous materials shipping regulations.
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1,3-Dibromo-2-Fluorobenzene 1,3-Dibromo-2-Fluorobenzene
General Information
Historical Development
1,3-Dibromo-2-fluorobenzene is also a chemical substance. Looking back at its historical development, in the past years, the research of chemistry has moved forward step by step. At the beginning, scholars explored the field of organic chemistry, and many substances were waiting to be revealed.
At that time, the exploration of halogenated aromatic hydrocarbons gradually flourished. Many researchers threw themselves into it, wanting to understand its properties and its uses. 1,3-dibromo-2-fluorobenzene also came into view, and everyone studied its synthesis method. The initial attempt was full of difficulties, and the road to synthesis was tortuous. However, scholars made unremitting efforts, through repeated experiments, improved the process, and gradually obtained effective methods. Its use in organic synthesis, material preparation and other fields has also become apparent with in-depth research. The historical development of this substance is one of the evidence of chemical progress, paving the way for subsequent scientific development.
Product Overview
There is a compound named 1,3-dibromo-2-fluorobenzene. It is an organic compound, either in the form of a colorless liquid or in a crystalline state, with a special odor.
In this compound, bromine and fluorine atoms are connected to the benzene ring in a specific order. Bromine is chemically active and can be used as a target for electrophilic reagents in many reactions; fluorine atoms affect the polarity and reactivity of molecules due to their strong electronegativity.
1,3-dibromo-2-fluorobenzene is widely used in the field of organic synthesis. It can be used as an intermediate to prepare various biologically active substances, such as drugs, pesticides, etc. Due to its unique structure, it can introduce other functional groups through specific chemical reactions, thus constructing more complex organic molecular structures, providing an important raw material basis for chemical research and industrial production.
Physical & Chemical Properties
1,3-Dibromo-2-fluorobenzene is an important substance in chemical research. Its physical and chemical properties are particularly critical. Looking at its physical properties, at room temperature, 1,3-dibromo-2-fluorobenzene has a specific color state, or is a colorless to light yellow liquid with a unique odor. The values of its boiling point and melting point are of great significance in chemical operation and application. The boiling point is related to its volatilization at a specific temperature, and the melting point affects its phase transition.
As for chemical properties, the presence of bromine and fluorine atoms in 1,3-dibromo-2-fluorobenzene gives it active chemical activity. Bromine atoms can participate in many substitution reactions, and the electronegativity of fluorine atoms also has a significant impact on the reactivity of molecules. In the field of organic synthesis, it is often a key intermediate. It can derive compounds with diverse structures through various chemical reactions, providing an important foundation for new drug development, materials science and many other fields.
Technical Specifications & Labeling
Today there is a product called 1,3-dibromo-2-fluorobenzene. In the field of chemistry, its technical specifications and identification (commodity parameters) are the key.
In terms of technical specifications, the preparation method needs to be strictly followed. From the selection of raw materials, it is necessary to be pure and free of impurities, and the amount should be precisely controlled, and it is not bad. The reaction conditions such as temperature, pressure, and duration are fixed, and there should be no slight excess. If the temperature is too high, side reactions will occur, and if it is too low, the reaction will be slow or even stagnant.
As for the identification (commodity parameters), its physical and chemical properties need to be detailed. Appearance color, odor, melting point, and solubility are all important. This is about the user's grasp of its characteristics, so that it can be applied to different scenarios. Precise technical specifications and clear identification (commodity parameters) are the foundation for the smooth development of 1,3-dibromo-2-fluorobenzene in chemical research and application.
Preparation Method
To prepare 1,3-dibromo-2-fluorobenzene, the method is as follows:
In terms of raw materials, fluorobenzene should be prepared as the base material, and an appropriate amount of bromine should be taken, supplemented by iron powder or iron tribromide as the catalyst.
In the production process, fluorobenzene is first put into the reaction kettle, and the catalyst is added in sequence, and then bromine is slowly added dropwise. The temperature is controlled in a specific range, and this reaction is appropriate to be mild to prevent side clumping.
In the reaction step, bromine and fluorobenzene are catalyzed to undergo electrophilic substitution. The bromine atom selects fluorobenzene and attacks it in the opposite position. After a series of transformations, 1,3-dibromo-2
refining mechanism, after the reaction is completed, the acid is washed with water, followed by alkali washing to adjust pH, and then distilled, rectified, etc., to purify the product to obtain high-purity 1,3-dibromo-2-fluorobenzene.
Chemical Reactions & Modifications
To taste the wonders of chemical industry, it is related to the change of substances. In the compound of 1,3-dibromo-2-fluorobenzene, the chemical reaction and modification are particularly important to our generation.
Fu 1,3-dibromo-2-fluorobenzene has a unique structure, and its bromine and fluorine atoms have different chemical activities. In conventional reactions, bromine is prone to nucleophilic substitution, while fluorine has strong electronegativity, which affects the reaction path. To modify the properties, you can borrow nucleophilic reagents to make bromine substituted with other groups, such as hydroxyl and amino groups, which are expected to obtain new functional compounds.
However, this reaction is not easy, and temperature control, solvent and catalyst selection are required. The presence of fluorine may increase the difficulty of the reaction, but it also gives the product unique properties. After optimizing the reaction, 1,3-dibromo-2-fluorobenzene can be modified, or it can be used in the fields of medicine and materials, contributing to the chemical industry.
Synonyms & Product Names
1,3-Dibromo-2-fluorobenzene is also a chemical substance. This substance is especially important in the way of my chemical research. Its synonymous name and the name of the commodity are also studied in detail by our generation.
Cover this 1,3-dibromo-2-fluorobenzene, or have another name to meet different situations and different uses. Its synonymous name refers to this specific chemical substance. Although the name is different in shape or shape, the quality it refers to is the same. As for the name of the product, the merchant may give it a special name according to its characteristics and uses, hoping to be different in the city.
When we study this object, we must study its synonymous name and the name of the commodity, in order to be able to gain knowledge in the field of chemistry, understand its nature, make good use of its capabilities, and in scientific research, we must be able to travel freely, adding bricks and mortar to the progress of chemistry.
Safety & Operational Standards
1,3-Dibromo-2-fluorobenzene, this chemical substance is essential for safety and operating standards.
In preparation and use, personal safety is the top priority. Those who handle this substance must wear complete protective equipment. Masks to prevent harmful gases from invading the mouth and nose, goggles to protect the eyes from splashing damage, and protective clothing and gloves to prevent skin contact. This is a necessary measure to avoid damage to the body.
Furthermore, the operating environment is also strictly regulated. It must be in a well-ventilated place, preferably a professional ventilation device, so that harmful volatile gases can be quickly discharged outside, so as not to accumulate in the room and endanger the person. And the operation area should be neat and orderly, and flammable and explosive objects should be kept away to prevent accidents.
When storing, caution is also required. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. The container must be tightly closed to prevent leakage from escaping. On the label, the name, characteristics, hazards and other information are readily available for easy identification and management.
If a leak unfortunately occurs, do not panic. Immediately evacuate unrelated personnel from the scene and set up warning signs. The operator is in front of professional protective equipment and adopts different measures according to the degree of leakage. A small amount of leakage can be collected by adsorption of inert materials such as sand and vermiculite; a large amount of leakage needs to be contained to prevent spread, and then a professional person can properly dispose of it.
All operations involving 1,3-dibromo-2-fluorobenzene should strictly abide by safety and operating standards, and there should be no slack in order to ensure people's safety and safety.
Application Area
1,3-Dibromo-2-fluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it is often the key raw material for the synthesis of special drugs, which can help doctors cure various diseases and save people's suffering. In material science, it is also indispensable, which can contribute to the development of new materials, making the materials have unique properties and suitable for a variety of scenarios. In the field of fine chemicals, this compound can become the cornerstone of manufacturing high-end fine chemicals and improve the quality and utility of chemical products. All of these demonstrate the value of 1,3-dibromo-2-fluorobenzene in various fields, and it is an important presence in chemical research and industrial production.
Research & Development
In recent years, I have studied a lot of chemical substances, especially 1,3 - Dibromo - 2 - Fluorobenzene. Its unique nature, wide range of uses, and potential in the fields of medicine and materials, so it led me to explore.
At the beginning, I analyzed its structure, observed its bonding, and understood its molecular state. Then, I studied its synthesis method, tried various paths, and found an efficient and pure recipe. The process was difficult, encountered obstacles repeatedly, the yield was not good, and the purity was not as expected. However, I was not discouraged, and I studied the classics in detail, asked my colleagues for advice, and finally obtained an improved method.
After repeated experiments, the conditions were optimized, and the yield gradually increased, and the purity was also in line with the standard. Looking at this object now, it has taken a new step in the path of scientific research. In the future, I hope to expand its use, promote the development of related fields, and contribute to the academic community.
Toxicity Research
Recently, Yu focused on the toxicity study of 1,3-dibromo-2-fluorobenzene. This chemical has attracted much attention in our chemical research field.
After repeated experiments, its toxicity was tested by ancient methods to observe its effect on various test subjects. In small animal experiments, the reaction after ingesting this chemical was observed. At first, the action was normal, but soon after, the state of fatigue gradually appeared, and the diet was also reduced. After dissection, there were slight changes in the organs, especially the liver and kidneys, with different colors and textures.
Another experiment was done with plants. When applied to cultivated plants, it was found that the growth rate slowed down, and the leaves gradually showed withered color, which seemed to be damaged.
Overall, 1,3-dibromo-2-fluorobenzene has certain toxicity and has adverse effects on the physiological function and growth and development of organisms. Follow-up studies should further explore its poisoning mechanism to find ways to prevent and resolve it, ensure the safety of all beings, and avoid its scourge.
Future Prospects
1,3-Dibromo-2-fluorobenzene is an organic compound. In today's chemical research, its characteristics and applications have gradually attracted the attention of the public. Although it is currently known or limited, it cannot be ignored for its future development.
The research of chemical substances in the past was mostly not seen by the public at first, and then it became new in the world. This 1,3-dibromo-2-fluorobenzene may have specific chemical activity, and it may become a new path in the art of synthesis. With time, after in-depth research by various scholars, it may be able to emerge in the fields of medicine and material manufacturing.
Those of us who are seeking research should take precautions and explore its subtleties with perseverance. It is expected that in the future, 1,3-dibromo-2-fluorobenzene will be able to shine in the chemical firmament, adding to the well-being of mankind. This is our eagerness for its future.
Where to Buy 1,3-Dibromo-2-Fluorobenzene in China?
As a trusted 1,3-Dibromo-2-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Dibromo-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-dibromo-2-fluorobenzene?
In the past, 1,3-dibromo-2-chloropropane was mainly used as a soil fumigant to control nematodes, fungi, bacteria and other harmful organisms in the soil, and played an important role in agricultural production. Its mechanism of action is that the substance can release biologically active halogen atoms, which can chemically react with biological macromolecules such as proteins and nucleic acids in organisms, thereby destroying their structure and function, resulting in the death of harmful organisms.
However, with the passage of time and in-depth research, it has been found that 1,3-dibromo-2-chloropropane has significant hazards to the environment and human health. It has strong bioaccumulation and persistence, is difficult to degrade in soil and water, and will remain for a long time and be transmitted through the food chain, causing damage to the ecosystem. At the same time, it has potential carcinogenic, teratogenic and mutagenic effects on the human body, and may threaten human health. In view of these risks, most countries have banned or severely restricted its use.
Although 1,3-dibromo-2-chloropropane used to be helpful for agricultural pest control, it has been gradually replaced by safer and more environmentally friendly alternatives due to its many hazards. This is the inevitable result of the deepening of human understanding of chemicals and the pursuit of sustainable development.
What are the physical properties of 1,3-dibromo-2-fluorobenzene?
1% 2C3-dibromo-2-pentenal is an organic compound with unique physical properties, detailed as follows:
1. ** Appearance properties **: Under normal conditions, 1% 2C3-dibromo-2-pentenal is often liquid, and its color may be colorless to light yellow. Its appearance is affected by impurities and purity. If it contains impurities, its color may be darker and its appearance may be more cloudy. This compound is widely used in the field of organic synthesis. Its liquid properties are easy to mix with other reagents and participate in the reaction. Due to the large contact area of liquid substances, the reaction is easier to proceed.
2. ** Odor **: The compound emits a special odor. Because its structure contains bromine atoms and aldehyde groups, it has a pungent and special smell. This odor is unique. When operating and using, it needs to be carried out in a well-ventilated environment to prevent inhalation of harmful gases from damaging health.
3. ** Melting boiling point **: The melting boiling point is an important physical property of the substance. The boiling point of 1% 2C3-dibromo-2-pentenal is related to the intermolecular force. Because the molecule contains polar groups, the intermolecular force is large and the boiling point is relatively high; the melting point is related to the degree of close arrangement of molecules. The specific melting boiling point value needs to be accurately determined by experiments, and will vary slightly due to differences in experimental conditions.
4. ** Solubility **: 1% 2C3-dibromo-2-pentenal is soluble in a variety of organic solvents, such as ethanol, ether, dichloromethane, etc. This is due to the principle of similar miscibility, and its molecular structure is similar to that of organic solvents, so it can dissolve each other. However, the solubility in water is limited, because the molecular polarity is not enough to form a strong interaction with water molecules. This solubility allows it to choose a suitable solvent according to the reaction requirements in organic synthesis to create suitable conditions for the reaction.
Is the chemical properties of 1,3-dibromo-2-fluorobenzene stable?
The chemical properties of 1% 2C3-dibromo-2-pentenal are not stable in common sense. In this compound, the bromine atom coexists with the alkenal structure, and the double bond of the alkenal and the aldehyde group are both active.
The double bond of the husband has a high electron cloud density, which is easy to be attacked by electrophilic reagents, resulting in the occurrence of addition reactions. In case of electrophilic reagents such as halogens and hydrogen halides, the double bond can be added to them, causing changes in the molecular structure. The aldehyde group is also very active and reductive, and can be oxidized by weak oxidants such as Torun reagent and Feilin reagent to form corresponding carboxylic acids. And aldehyde groups can undergo nucleophilic addition reactions, such as forming acetals with alcohols, or reacting with nucleophilic reagents such as Grignard reagents to form new compounds.
And bromine atoms are connected to the carbon chain, and under appropriate conditions, a substitution reaction can occur. Due to the large electronegativity of bromine atoms, the carbon-bromine bonds connected to them have a certain polarity, which is vulnerable to nucleophilic attack, and bromine atoms are replaced to derive new compounds.
Furthermore, the conjugation effect within the molecule also affects its chemical properties. The conjugation system formed by the alkylene structure makes the electron cloud distribution more uniform, which affects the stability and reactivity of the molecule. Although the conjugated system can increase its stability to a certain extent, on the whole, the chemical properties of 1% 2C3-dibromo-2-pentenal due to the coexistence of multiple active groups are not stable. Under suitable conditions, it is easy to have a variety of chemical reactions and derive a variety of compounds.
What are the synthesis methods of 1,3-dibromo-2-fluorobenzene?
The synthesis methods of 1% 2C3-dibromo-2-butene generally include the following:
First, butadiene is used as the starting material. Butadiene and bromine can undergo an addition reaction under suitable reaction conditions. In this process, it is necessary to precisely control the reaction temperature, the proportion of reactants and other factors. If the reaction temperature is too high, or the amount of bromine is too high, it is easy to cause excessive addition and form polybrominated products; if the temperature is too low, the reaction rate is slow and the yield is not good. Generally speaking, at low temperatures and in the presence of suitable catalysts, the reaction can mainly generate 1% 2C3-dibromo-2-butene. The raw material butadiene of this route is easy to obtain, and the reaction mechanism is relatively clear, so it is more commonly used in industrial production and laboratory synthesis.
Second, it can be started from specific alcohol derivatives. For example, using 2-butene-1% 2C4-diol as raw material, first perform appropriate protective group operation on it, and then react with bromine-containing reagents to introduce bromine atoms. After that, the target product 1% 2C3-dibromo-2-butene is obtained through steps such as deprotection. Although this method is slightly complicated, the control of the reaction conditions is more delicate, which can effectively improve the purity and yield of the product. In the case of strict product quality requirements, this path is often used.
Third, halogenated olefins are used as starting materials. For example, selecting suitable monohalobutenes and reacting with brominating reagents under the action of catalysts to achieve the introduction of bromine atoms to construct the structure of 1% 2C3-dibromo-2-butene. This method requires careful screening of catalysts and reaction conditions according to the structural characteristics of the starting halogenated olefins to achieve the best reaction effect. Its advantage is that it can provide more strategies for synthesis by diversifying the selection of starting materials.
What are the precautions for storing and transporting 1,3-dibromo-2-fluorobenzene?
1% 2C3-dibromo-2-pentene is an organic compound. When storing and transporting, the following things should be paid attention to:
First, the storage environment must be cool and well ventilated. This substance is easy to decompose when heated, and the high temperature environment may cause it to deteriorate and even cause dangerous reactions. Therefore, heat sources and fire sources, such as boilers, heating equipment, etc., should be avoided. And good ventilation can prevent its steam from accumulating locally and reduce the risk of explosion.
Second, it needs to be strictly sealed for storage. 1% 2C3-dibromo-2-pentene is volatile, poor sealing is easy to cause volatilization loss, and its steam may be harmful to the human body. Sealed storage can avoid steam escape. Storage containers should be made of suitable materials, such as glass or specific plastic containers, to prevent chemical reactions with the container.
Third, ensure that the container is stable during transportation. Avoid collisions and vibrations to prevent leakage of 1% 2C3-dibromo-2-pentene due to container rupture. Vehicles should drive smoothly, do not brake or make sharp turns. Transportation tools should be equipped with necessary emergency equipment and protective equipment. If there is a leak, it can be dealt with in time.
Fourth, it should be stored and transported separately from oxidants, acids and other substances. 1% 2C3-dibromo-2-pentene comes into contact with these substances, or has violent chemical reactions, causing serious accidents such as fire and explosion.
Fifth, the operation and transportation personnel need to be professionally trained. Familiar with the characteristics of 1% 2C3-dibromo-2-pentene, dangerous hazards and emergency treatment measures. Wear appropriate protective equipment, such as gas masks, protective gloves, etc. during operation to ensure your own safety.