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1,3-Bis(Trifluoromethyl)-Benzenee

1,3-Bis(Trifluoromethyl)-Benzenee

Hongda Chemical

Specifications

HS Code

259170

Chemical Formula C8H4F6
Molecular Weight 214.11
Appearance Colorless liquid
Boiling Point 140 - 142 °C
Melting Point -36 °C
Density 1.439 g/cm³
Vapor Pressure 1.4 kPa (20 °C)
Solubility In Water Insoluble
Flash Point 32 °C
Refractive Index 1.378

As an accredited 1,3-Bis(Trifluoromethyl)-Benzenee factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,3 - bis(trifluoromethyl) - benzene in 500 - gram bottles for packaging.
Storage 1,3 - bis(trifluoromethyl) - benzene should be stored in a cool, dry, well - ventilated area, away from sources of heat, ignition, and oxidizing agents. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it in a dedicated chemical storage cabinet to prevent accidental spills and ensure proper segregation from incompatible substances.
Shipping 1,3 - bis(trifluoromethyl) - benzene is a chemical. Shipping should be in accordance with hazardous chemical regulations. Use proper packaging to prevent leakage, and ensure compliance with transport safety standards during transit.
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1,3-Bis(Trifluoromethyl)-Benzenee 1,3-Bis(Trifluoromethyl)-Benzenee
General Information
Historical Development
1,3-Bis (trifluoromethyl) benzene is also a chemical substance. It began in the path of scientific research, and over the years, it has gradually become more and more important in the academic community. In the past, researchers explored its nature and characteristics in the midst of numerous experiments. At the beginning, the cognition was still shallow, and only a little knowledge of the fur. However, as time went by, the study deepened, and the understanding of its structure and reaction characteristics gradually increased. From the initial exploration of ignorance, to the ability to accurately control its participation in various reactions, the process is like seeing through the clouds. Many difficulties in the past can now be solved. In the past, it only existed in the application of ideas, but now it has gradually become a reality. It has emerged in the fields of materials, medicine, etc. Its development path is becoming more and more extensive, and the prospect is promising.
Product Overview
1,3-Bis (trifluoromethyl) benzene, this compound is a key substance in the field of organic chemistry. Its appearance is colorless and transparent to light yellow liquid with a special odor.
This substance is widely used in the chemical industry. In materials science, it can be used as a monomer for the synthesis of special polymer materials. With its unique fluorine-containing structure, it endows the material with excellent chemical stability, thermal stability and low surface energy. In the field of medicinal chemistry, it is also an important intermediate for the synthesis of drug molecules with specific physiological activities.
Preparation of 1,3-bis (trifluoromethyl) benzene often requires fine chemical processes. Using specific aromatic hydrocarbons as starting materials, trifluoromethyl groups are introduced through multi-step reactions such as halogenation and nucleophilic substitution. Each step requires precise control of reaction conditions, such as temperature, catalyst type and dosage, to ensure product purity and yield.
With the advancement of science and technology, the research and application of 1,3-bis (trifluoromethyl) benzene will continue to expand, providing key support for the development of many fields.
Physical & Chemical Properties
1,3-Bis (trifluoromethyl) benzene is also an organic compound. Its physical and chemical properties are related to chemical research. At room temperature, this substance is mostly in a liquid state and has a special odor. Looking at its physical properties, the boiling point is moderate, which is conducive to separation and purification. Its solubility, in common organic solvents, has a unique performance, either soluble or slightly soluble, which varies depending on the properties of the solvent.
In terms of its chemical properties, the benzene ring structure gives it a stable base, but the introduction of trifluoromethyl adds reactivity. It can participate in many chemical reactions, such as electrophilic substitution, and guide the direction of the reaction with its electronic effect. And because of its fluoride content, it has special chemical activity and is often a key component in the field of material synthesis and drug research and development. Researchers should study its physical and chemical properties in detail to expand its application and increase innovation for the chemical, pharmaceutical and other industries.
Technical Specifications & Labeling
Today there is a product called 1,3-bis (trifluoromethyl) -benzene. The preparation of this substance is related to technical specifications and identification (product parameters), which is quite important.
To make this product, it is necessary to follow precise process procedures. From the selection of raw materials, it is necessary to be pure and refined, and impurities must be removed. Reaction conditions, such as temperature, pressure, and duration, must be strictly controlled. Slight temperature differences may cause reactions to be biased and the product is impure. Improper pressure also affects the quality and quantity of production.
In terms of labeling, the product parameters should be clear. The proportion and purity of the ingredients contained should be listed in detail. In this way, the user can know its characteristics and make good use of it. This technical specification and identification (product parameters) are indispensable for the production and application of 1,3-bis (trifluoromethyl) -benzene and must be treated with caution.
Preparation Method
The method of making 1,3-bis (trifluoromethyl) -benzene involves raw materials and production processes, reaction steps and catalytic mechanisms. The selection of raw materials needs to be carefully selected to ensure the quality of the material. In the production process, every step must be precisely controlled. At the beginning of the reaction step, the reactants are mixed in a specific ratio and placed in an appropriate reaction vessel. Under appropriate temperature and pressure, the reaction is initiated. In this process, the catalytic mechanism is particularly critical. The selection of a suitable catalyst can speed up the reaction process and increase the purity of the product. For example, with a special catalyst input, the reaction rate is regulated, and the reaction is advanced in an orderly manner, so that 1,3-bis (trifluoromethyl) -benzene can be efficiently prepared, providing high-quality raw materials for chemical production.
Chemical Reactions & Modifications
Taste the way of chemical industry, endless changes, material changes, related to skills and wisdom. Today there is 1,3 - Bis (Trifluoromethyl) - Benzenee, its chemical reaction and modification, I sincerely study the heart of the generation.
To view its reaction, it is necessary to examine the temperature of its environment and the nature of the medium. High temperature will cause the reaction speed, but it is easy to be messy; low temperature will slow down, or it will be difficult to form. The medium, or to help it combine, or to promote its division, is the key.
As for modification, to increase its stability, you can introduce groups to fix its structure; to change its properties, or to adjust the length and angle of its bonds. In this way, it is expected to obtain products with outstanding performance, which can be used in the fields of medicine and materials. We should make every effort to explore its subtleties in order to transform the environment, and hope that the reaction and modification of things will make breakthroughs to benefit the world.
Synonyms & Product Names
1,3-Bis (trifluoromethyl) benzene, also known as trifluoromethyl benzene isomer. Its shape is colorless and has a special odor. It is an essential material for organic synthesis. It is widely used in medicine, pesticides, materials and other fields.
Looking at its preparation, it is mostly halogenated, fluorinated and other methods. During synthesis, the ratio of raw materials, reaction temperature and duration must be controlled. Optimize conditions to improve yield and purity.
In the market, this product has different trade names, but they all refer to this product. Developers seek better synthetic paths and expand application fields, hoping to develop its potential and develop greater use in various industries.
Safety & Operational Standards
1,3-Bis (trifluoromethyl) benzene, the safe production and operation of this substance is very important.
Its special properties are important raw materials for organic synthesis. During the preparation process, the first priority is environmental safety. It is necessary to choose a well-ventilated place to prevent the accumulation of harmful gases. And the operation room should be away from fire and heat sources, because it is flammable, in case of open flame, hot topic, or risk of combustion and explosion.
When taking it, it is necessary to adapt protective equipment. Operators should wear protective gloves to prevent skin contact, because it may irritate the skin, cause discomfort and even damage. The face also needs protective gear, such as a gas mask, to avoid inhaling its volatile gas. If this gas enters the body, it may damage the respiratory tract and other organs.
When storing, it should be placed in a cool, dry and well ventilated place. The container must be well sealed to prevent leakage. If it leaks accidentally, do not panic. Small leaks should be quickly adsorbed with inert materials such as sand and vermiculite, collected in a closed container, and disposed of according to regulations. If there are large leaks, people should be evacuated quickly, the scene should be sealed, and reported to a professional emergency team for handling.
Experimental operation procedures should also be followed strictly. Before the experiment, check whether the instrument is in good condition and whether the device is tightly connected. During operation, control the temperature and speed, and follow the established steps. Do not change the process without authorization. After the reaction is completed, properly dispose of the remaining materials and do not dump them at will to prevent pollution to the environment.
In short, in the production and operation of 1,3-bis (trifluoromethyl) benzene, all aspects must strictly abide by safety and operating standards to ensure the safety of personnel, protect the environment and promote the smooth production and scientific research.
Application Area
1,3-Bis (trifluoromethyl) benzene, which is used in many fields. In the field of pharmaceutical research and development, its unique structure can be used as a key intermediate to help create special new drugs and contribute to the treatment of diseases. In the field of materials science, with its characteristics, it can improve material properties, such as increasing its stability and weather resistance, and is used in the preparation of high-tech materials, laying the foundation for material innovation. In the field of fine chemicals, it can participate in the synthesis of high-end fine chemicals, improve product quality, and meet diverse industrial needs. With its unique properties, this compound is like a shining star in various application fields, injecting new impetus into the development of various industries, promoting the continuous progress of science and technology and industry, and paving the way for innovative development in medicine, materials and chemical industry.
Research & Development
Yu Taste is dedicated to the research of 1,3 - Bis (Trifluoromethyl) - Benzenee. The properties of this substance are unique and have potential applications in various fields of chemical industry. When I first got involved in its research, many difficulties lay ahead, such as the difficulty of purification and the harsh reaction conditions. However, I did not give up, and tried repeatedly to study the mechanism.
After months of research, I gradually gained something. Optimize the reaction process and improve the purification method, so that the purity of the product and the yield can increase. And its physicochemical properties and reactivity are clearly recognized. Looking at this achievement today, although it is still small, it is of great significance to me. It is hoped that in the future, it can further expand its application, broaden its effectiveness, and contribute to research and development, so that this material can flourish in more fields and benefit the world.
Toxicity Research
Recent studies on the toxicity of 1, 3 - Bis (Trifluoromethyl) - Benzenee are quite important. Observing the study of Fugu is all about the nature of heavy objects, and now this chemical should also be carefully observed.
After various experiments, test its effect on life. Take insects and rats as tests to observe the changes in their diet, action and reproduction. Observe that if this chemical is involved in excess, insects are easy to die, rats are also in a state of decline, and there may be damage to their organs.
And observe its nature in the environment, in water and soil, it is not easy to dissolve, or it is tired of ecology. Although there is a small amount of time, there is no serious danger for the time being, but it will accumulate for a long time, and it may become a serious harm. Therefore, its use should be used with caution, and its toxicology should be studied in detail, so as to prevent life from being destroyed and ecological disorder. In this way, the way of learning is combined to ensure the peace of the world.
Future Prospects
There is a thing now, called "1,3-bis (trifluoromethyl) benzene". The research and development of this thing is related to the future development. Our chemists, the heart is attached to it, and the ambition is also there.
Looking at this substance, its structure is unique, its characteristics are unique, and it has undiscovered potential in various fields. In industry, it may be the key to material improvement, increasing its durability and corrosion resistance; in the road of medicine, it may be used as the cornerstone of innovative drugs, opening up new paths of anti-disease treatment.
Although its application is not widespread at this moment, I firmly believe that with time, with the research of all researchers, its advantages will be fully demonstrated. In the future, 1,3-Bis (trifluoromethyl) benzene will emerge in various industries, bring new changes to the world, and become a bright pearl on our scientific research road, creating a new situation and benefiting all people.
Where to Buy 1,3-Bis(Trifluoromethyl)-Benzenee in China?
As a trusted 1,3-Bis(Trifluoromethyl)-Benzenee manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Bis(Trifluoromethyl)-Benzenee supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-bis (trifluoromethyl) benzene?
1% 2C3-bis (triethylamino) benzene is one of the organic compounds. Its main uses are quite extensive, and are described in detail as follows:
First, in the field of organic synthesis, this compound is often used as an important intermediate. Due to its unique structure, it can be converted into other complex organic molecules through many chemical reactions. For example, through nucleophilic substitution reactions, coupling reactions, etc. combined with different reagents, various organic compounds with special functions or structures are constructed, providing key raw materials for the development of organic synthesis chemistry.
Second, in the field of materials science, 1% 2C3-bis (triethylamino) benzene is also of great value. It can participate in the synthesis process of polymer materials and give the material specific properties. Such as improving the solubility, thermal stability, electrical properties of the material. With the help of reasonable molecular design, it can be introduced into the polymer skeleton to prepare functional materials suitable for different scenarios, such as electronic device materials, optical materials, etc.
Third, in the field of catalysis, the compound can sometimes be used as a ligand. After coordinating with metal ions, the formed metal complexes often show unique catalytic activity and selectivity. It can be applied to various catalytic reactions, such as hydrogenation reactions, oxidation reactions, etc., to help improve the efficiency of the reaction and the purity of the product, which is of great significance for the optimization of chemical production.
Fourth, in the field of medicinal chemistry, derivatives of 1% 2C3-bis (triethylamino) benzene may have potential biological activity. By modifying and modifying its structure, it is expected to develop new drug molecules. It can be used for the binding research of drug targets, as well as the discovery and optimization of lead compounds, providing new opportunities and directions for the creation of new drugs.
In summary, 1% 2C3-bis (triethylamino) benzene plays an important role in many fields such as organic synthesis, materials science, catalysis and medicinal chemistry, and is of great significance to promote the development and practical application of related disciplines.
What are the physical properties of 1,3-bis (trifluoromethyl) benzene?
1,3-Bis (triethylamino) benzene is an organic compound. Its physical properties are quite unique and are described as follows:
Under normal temperature and pressure, it is mostly colorless to light yellow transparent liquid. Its appearance is clean and fluid, which can be regarded as a characterization. Its smell, with a special aromatic charm, is not pungent and intolerable, slightly volatile, and can be gradually diffused when placed in the air.
When it comes to solubility, this compound has good solubility in many organic solvents. Organic solvents such as common ethanol, ether, and chloroform are mixed with each other to form a uniform solution. This property is compatible with each other because the groups contained in the molecular structure can form appropriate interaction forces with organic solvent molecules, such as van der Waals forces, hydrogen bonds, etc.
As for the boiling point, its boiling point is in a specific temperature range. Due to the existence of certain interactions between molecules, in order to transform it from a liquid state to a gas state, a certain amount of energy needs to be supplied to overcome the attractive force between molecules. Specifically, its boiling point value makes the vapor pressure of the liquid equal to the external atmospheric pressure at the corresponding temperature, and then the boiling phenomenon occurs. The characteristics of this boiling point are of great significance in separation, purification and reaction operations at specific temperature conditions.
Melting point is also one of the key indicators of its physical properties. When the temperature drops to a certain level, the thermal motion of the molecules weakens, and the arrangement between them tends to be orderly. The compound solidifies from liquid to solid, and this temperature is the melting point. The exact value of the melting point reflects the strength of the binding force between molecules and the stability of the crystal structure, which can provide an important basis for the identification and purity determination of the compound.
In terms of density, it has a certain value, which indicates the mass of the substance per unit volume. The characteristics of density are indispensable in practical application scenarios such as mixing, separation, and container loading. Due to the different densities of different substances, separation operations can be achieved by methods such as centrifugation and stratification.
Is the chemical properties of 1,3-bis (trifluoromethyl) benzene stable?
1% 2C3 -bis (triethyl) benzene, its chemical properties are quite stable. Cover this kind of compound, the molecular structure contains benzene ring, benzene ring has conjugated large π bond, this structure gives it a certain stability.
The electron cloud of the benzene ring is evenly distributed, and the conjugated system can disperse electrons, so that the molecular energy is reduced, and it is not easy to react with general reagents. The substituent of triethyl also affects the properties of the benzene ring. It is the power supply group, which can increase the electron cloud density of the benzene ring, but this increase is not enough to destroy the original stable structure of the benzene ring.
Under common chemical reaction conditions, such as room temperature and pressure, without special catalysts or strong reaction conditions, 1% 2C3 -bis (triethylmethyl) benzene is difficult to undergo significant chemical changes. In the oxidation reaction, if there is no strong oxidant and specific reaction conditions, the benzene ring structure can be maintained stable. Even in the case of common electrophilic reagents, the reaction is not easy to occur due to the conjugation protection of the benzene ring electron cloud.
However, it should be noted that the stability of chemical substances is not absolute. If placed at high temperature, high pressure, or under extreme conditions such as strong oxidants, strong acids, and strong bases, its stable structure may be damaged, triggering various chemical reactions, which is no longer the case. In conclusion, the chemical properties of 1% 2C3-bis (triethylmethyl) benzene are relatively stable under conventional conditions.
What are the preparation methods of 1,3-bis (trifluoromethyl) benzene?
1% 2C3-bis (triethyl alkyl) benzene can be prepared by the following methods:
First, benzene and triethyl alkyl halide are used as materials, and the reaction of Fu-gram alkylation is catalyzed by Lewis acid. Among them, Lewis acid is commonly used such as anhydrous aluminum trichloride, ferric chloride, etc. The mechanism of the reaction is that Lewis acid interacts with the halide to dissociate the halogen atom to form an alkyl positive ion, which in turn undergoes electrophilic substitution with the benzene ring to obtain 1% 2C3-bis (triethyl alkyl) benzene. For example, benzene and 1-chloro-triethyl alkyl are catalyzed by anhydrous aluminum trichloride in a suitable solvent (such as dichloromethane), and the reaction is stirred at temperature. After post-treatment, such as separation, washing, distillation, etc., the target product can be obtained. Second, benzene and triethyl alkyl halide of one molecule are first alkylated by Fu-g to obtain a substituted product, and then the product is used as a substrate. Repeat the above-mentioned Fu-g alkylation process to obtain 1% 2C3-bis (triethyl alkyl) benzene. This way, the selectivity and yield of the target product can be improved by adjusting the reaction conditions, such as the ratio of reactants, reaction temperature, and catalyst dosage. Third, benzene and triethyl borate can be used as raw materials to carry out arylation reaction under the action of transition metal catalysts. Transition metal catalysts such as palladium catalysts, ligands such as phosphine ligands, etc. The reaction conditions are relatively mild and environmentally friendly, and it is also expected to achieve the preparation of 1% 2C3 -bis (triethyl alkyl) benzene. After the reaction, the pure product can be obtained by means of separation and purification.
What are the precautions for storing and transporting 1,3-bis (trifluoromethyl) benzene?
For 1% 2C3-bis (triethoxysilyl) benzene, many matters must be paid attention to during storage and transportation.
First, the storage place must be dry and cool. This compound is prone to hydrolysis in contact with water, causing it to deteriorate and fail. If the environment is humid, water vapor easily interacts with the ethoxy group of the silicon group, destroying its chemical structure. Therefore, it should be stored in a dryer, or sealed in a moisture-proof container, and the warehouse temperature should be controlled within an appropriate range to avoid changes in reaction activity due to excessive temperature, or crystallization due to low temperature, which affects its performance.
Second, when transporting, ensure that the packaging is tight. Due to its lively chemical properties, if it is slightly careless, it is easy to come into contact with external substances if the packaging is damaged. If the packaging material is not good, it will not only lose materials, but also cause pollution to the transportation environment and even cause safety accidents. Choose corrosion-resistant and well-sealed materials for packaging, such as special plastic drums or metal drums, and do a good job of reinforcement protection to prevent collision damage during transportation.
Furthermore, avoid mixing with oxidants, acids, alkalis and other substances. The chemical structure of 1% 2C3-bis (triethoxysilyl) benzene determines that it is prone to chemical reactions with such substances. In case of strong oxidizing agent, it may cause severe oxidation reaction, or cause combustion and explosion; in case of acid and alkali, it will also promote the hydrolysis of ethoxyl or other chemical reactions, changing its chemical properties. Therefore, during transportation and storage, it is necessary to strictly separate from the above substances.
In addition, operators should also have professional knowledge and skills. Whether it is the daily management during storage, or the transportation and loading and unloading process, personnel need to understand the characteristics of the compound and follow the correct operation process. When storing, they can detect the impact of environmental changes in time, and handle it properly during transportation and loading to avoid improper operation and damage to packaging and material leakage.