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1,3-Bis-Trifluoromethyl Benzene

1,3-Bis-Trifluoromethyl Benzene

Hongda Chemical

Specifications

HS Code

827502

Chemical Formula C8H4F6
Molar Mass 214.11 g/mol
Appearance Colorless liquid
Odor Characteristic odor
Density 1.374 g/cm³
Boiling Point 117 - 118 °C
Melting Point -39 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Vapor Pressure At 25 °C, relatively low vapor pressure

As an accredited 1,3-Bis-Trifluoromethyl Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,3 - bis - trifluoromethyl Benzene in 500 - mL glass bottle for chemical packaging.
Storage 1,3 - bis - trifluoromethyl benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container, preferably made of corrosion - resistant materials like stainless steel or certain polymers. Avoid storing it near oxidizing agents. Keep the storage area dry to prevent any potential hydrolysis reactions.
Shipping 1,3 - bis - trifluoromethyl Benzene is shipped in accordance with strict chemical transportation regulations. It's typically in sealed, corrosion - resistant containers, safeguarded from heat, sparks, and incompatible substances during transit.
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1,3-Bis-Trifluoromethyl Benzene 1,3-Bis-Trifluoromethyl Benzene
General Information
Historical Development
1,3-Bis-trifluoromethylbenzene, its substance is also in the field of chemistry, and it gradually shows its brilliance. In the past, many chemical sages studied the properties of substances, but did not realize that this substance was special. However, times change, science and technology are new, and many sages are exploring, but suddenly they feel that it is extraordinary.
At first, it is only known that it is an organic body with a special structure and contains trifluoromethyl. Later, it gradually became clear that it has a unique activity in the reaction and can form different bonds, opening up new ways of synthesis. With the depth of research, it has emerged in the fields of materials and medicine. It was not used in the past, but can be found everywhere today. It is a witness to the development of chemistry. From ignorance to good use, this is the development trajectory of 1,3-bis-trifluoromethylbenzene.
Product Overview
1,3-Bis (trifluoromethyl) benzene, an organic compound. It is a colorless and transparent liquid with a special odor. The boiling point is about 128-129 ° C, the density is lighter than that of water, and it is insoluble in water. It can be miscible in most organic solvents.
This compound has a wide range of uses in the field of organic synthesis. It is often used as a solvent to assist in the progress of various reactions. Due to its special structure, it can stabilize the reaction environment and improve the reaction efficiency. It is also a key raw material for the preparation of various fluorine-containing compounds, and plays an important role in the fields of medicine, pesticides, and materials science. For example, when creating new drugs, the introduction of fragments containing this structure can change the physical and chemical properties of the compound and improve its biological activity and pharmacological properties. In the development of materials, through their participation in synthesis, materials can be endowed with special electrical, optical or thermal properties to meet the needs of different scenarios.
Physical & Chemical Properties
1,3-Bis-trifluoromethylbenzene, its physical and chemical properties can be studied. Looking at its shape, at room temperature, it is a colorless and transparent liquid with a special odor. Its boiling point is about 187-188 ° C, the melting point is -57 ° C, and the density is 1.443g/cm ³. This substance is insoluble in water, but it can be miscible with most organic solvents.
In terms of its chemical properties, 1,3-bis-trifluoromethylbenzene has considerable stability. Because it contains trifluoromethyl, the density distribution of the electron cloud is specific, so its chemical activity is different from that of the general benzene series. It can be used as an intermediary in organic synthesis and is used in the fields of medicine, pesticides and materials. Due to its physical and chemical characteristics, it can exhibit unique reaction paths and products under various reaction conditions, making it an important raw material for chemical synthesis.
Technical Specifications & Labeling
Today there is a product named 1,3-Bis-trifluoromethylbenzene. To clarify its technical specifications and labels (product parameters), you should check it carefully.
This 1,3-Bis-trifluoromethylbenzene, its purity is the key. It must be tested with accurate methods, so that there are very few impurities, so that it can meet the needs. Its color should be clear, no variegated stains; the taste should be pure, no odor disturbance.
And its boiling point, melting point and other parameters also need to meet specific regulations. The boiling point is related to its gasification state; the number of melting points is determined when it coagulates.
As for the logo, it should be clear. On the packaging, the name is written in detail, marked with the chemical formula, stating its characteristics and precautions, so that the viewer knows the details and is safe to use. In this way, the main meaning of the technical specifications and labels of 1,3-bis-trifluoromethylbenzene is obtained.
Preparation Method
The method of making 1,3-bis-trifluoromethylbenzene involves raw materials and production processes, reaction steps and catalytic mechanisms. First, an appropriate amount of specific raw materials is taken, and according to the precise ratio, they are put into a special reactor. A specific catalyst is preset in the kettle, which can change the rate of chemical reaction and make the reaction proceed efficiently.
Initially, adjust the reaction to a suitable temperature and pressure, which are the key conditions for the reaction. The temperature is controlled in a certain range, and the pressure is also maintained stable, so that the raw materials can be fully reacted in the kettle. After a period of time, the reaction process is advanced in an orderly manner according to the specific reaction steps.
After the reaction is completed, the product is finely separated and purified to remove impurities and obtain pure 1,3-bis-trifluoromethylbenzene. The whole process, the selection of raw materials, the control of reaction conditions, the sequence of steps and the catalytic effect are all essential for the preparation of good products.
Chemical Reactions & Modifications
I tried to study the chemical reaction and modification of 1,3-Bis-Trifluoromethyl Benzene. The properties of this compound are different, and its chemical reaction path is worth exploring. In past experiments, according to conventional methods, the reaction results were not expected. Then I thought about changing it, and changed the reaction conditions, such as adjusting the temperature and changing the solvent. After several trials, the best path was gradually obtained. When the temperature rose to an appropriate temperature, a special solvent was used instead, and the reactivity was greatly increased, and the quality and quantity of the product were improved. When modifying, specific groups were introduced to make its performance better, and it was used in many fields or more widely. In view of it, the chemical reaction and modification were not achieved overnight, and it was necessary to study and think carefully, keep trial and error, and then we can get exquisite methods to make the best use of this compound.
Synonyms & Product Names
1,3-Bis (trifluoromethyl) benzene, this substance is also called m-bis (trifluoromethyl) benzene. Although its name is different, it is actually the same substance. I have been studying this substance for many years.
Looking at its physical properties, under room temperature, it is a colorless liquid with a special odor. Its boiling point and melting point are fixed, and it is widely used in the field of organic synthesis. It can be used as a solvent and is also a key raw material for the preparation of a variety of fine chemicals.
In the process of industrial preparation, it has undergone multiple methods. Or it is obtained from a specific halogenated aromatic hydrocarbon through complex reactions; or it is obtained by taking another starting material and transforming it according to a specific process. Although the preparation method is not the same, they all strive for high yield and excellent quality.
Although the name of this 1,3-bis (trifluoromethyl) benzene is different, its importance in the chemical industry should not be underestimated. We need to study it in depth to develop more uses and benefit the world.
Safety & Operational Standards
1,3-Bis (trifluoromethyl) benzene is a commonly used raw material in the chemical industry. It is related to the production of products in many fields. Its safety and operation standards are extremely important, and it is related to the safety of practitioners and the smooth production.
This product is toxic to a certain extent. Inhalation, ingestion or absorption through the skin can cause human damage. Light dizziness, headache, nausea, vomiting, and severe cases may affect the function of the nervous system, liver and other organs. Therefore, contact with this substance requires strict safety regulations.
When operating, the workplace must be well ventilated to reduce the concentration in the air. Practitioners wear protective clothing, protective gloves and goggles to avoid contact between skin and eyes. If it is accidentally touched, it should be flushed with a large amount of water as soon as possible. If the situation is serious, it must be urgently sent to the hospital.
Furthermore, the use of this product requires accurate measurement and strict operation procedures. Due to its active chemical nature, improper operation may lead to serious accidents such as combustion and explosion. When taking it, special equipment should be used, and it should be taken in accordance with regulations. And the operation process should be kept away from fire and heat sources.
Storage is also exquisite. It should be stored in a cool and ventilated warehouse, away from fire and heat sources. The storage temperature should not exceed 30 ° C. It should be stored separately from oxidants and edible chemicals, and should not be mixed. The storage area should be prepared with suitable materials to contain leaks.
In conclusion, the safety and operation specifications of 1,3-bis (trifluoromethyl) benzene are the key links in chemical production. Practitioners should be familiar with and strictly practice to ensure safe and efficient production.
Application Area
1,3-Bis-trifluoromethylbenzene has a wide range of uses. In the genus of medicinal chemistry, it can be used as a raw material for the synthesis of various drugs. With its unique structure, it can increase the fat solubility of drugs, promote their transmembrane transportation, and improve the effect of drugs. And in the production of pesticides, it also has its function. It can give pesticides good biological activity, inhibit the reproduction of pests, and protect the growth of farmers and plants. In addition, in the context of material science, it can be synthesized into special polymers, so that the material has excellent weather resistance and corrosion resistance, and is suitable for harsh environments. From this point of view, 1,3-bis-trifluoromethylbenzene is heavy in multiple domains and is indispensable for chemical research and production.
Research & Development
In recent years, I have focused on the research of 1,3-Bis-Trifluoromethyl Benzene. This substance has unique properties and great potential in many fields.
At the beginning, I explored its synthesis path, but it has been subject to many twists and turns. The traditional method is either expensive or the yield is low. I studied day and night, looking up the classics, as if I were in a fog, trying to find an exit.
Then, I tried new ideas, used other raw materials, supplemented by exquisite proportions, and finally obtained the optimization method. The yield gradually increased, and the purity was also high.
As for applications, in materials science, polymers with special properties can be produced; in the field of medicine, it is expected to become a key ingredient in innovative drugs.
Looking at it now, although this research has been successful, there is still a long way to go. Many details are yet to be perfected, and many possibilities are yet to be discovered. I will make unremitting efforts to promote the wide application of this material and contribute to the academic and industrial circles.
Toxicity Research
When I hear that there is something today, it is called "1,3-bis-trifluoromethylbenzene". Our generation of chemical researchers should study its wonders, especially its toxicity.
The toxicity of this thing is related to the health of all living beings and cannot be ignored. Examine its properties in detail. During the experiment, observe its response to various things in detail, and observe its shadow on living things. Or observe its entry into the body, the changes; or see its skin contact, the reaction.
The study of toxicity is not only about the present, but also involves the long term. If it escapes from the outside, enters rivers, lakes and seas, and seeps into soil and rock layers, it may cause ecological changes. Organisms bear its harm, the food chain is chaotic, and the ecology is difficult to balance.
We should study the toxicity of "1,3-bis-trifluoromethylbenzene" with a rigorous heart and scientific method, so that the world can understand its benefits, protect the safety of all things, and protect the ecology.
Future Prospects
With 1,3-bis-trifluoromethylbenzene, it is also a good product in chemistry. Viewing its properties, it has specific qualities, and is expected to show extraordinary uses in various fields.
Although we are in the process of research and development today, the future is bright and promising. In the field of materials, it may help to make quirky materials, increase their properties and expand their uses, and contribute to the progress of engineering and technology. On the road of medicine, or with its characteristics, explore the system of new drugs, and save the sick from the pain.
Although there may be thorns in the road ahead, we chemical researchers, with grand ambitions, must devote our efforts to investigate its secrets. Over time, make this product shine, for the progress of the world, the blessing of people, and the development of endless energy. At that time, 1,3-Bis-trifluoromethylbenzene will be a strong aid for future development and a cornerstone of our generation's scientific research.
Where to Buy 1,3-Bis-Trifluoromethyl Benzene in China?
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Frequently Asked Questions

As a leading 1,3-Bis-Trifluoromethyl Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-bis (trifluoromethyl) benzene?
1% 2C3-bis (triethylamino) benzene, this substance has important uses in many fields.
In the field of organic synthesis, it can be used as a key intermediate. The triethylamino group contained in its structure has specific electronic effects and steric resistance, and can participate in many organic reactions. For example, in nucleophilic substitution reactions, the nucleophilic properties of amino groups can react with substrates such as halogenated hydrocarbons to form new carbon-nitrogen bonds, thereby synthesizing a series of nitrogen-containing organic compounds, providing key structural units for pharmaceutical chemistry, materials science and other fields.
In the field of catalysis, 1% 2C3-bis (triethylamino) benzene can be used as a ligand. After coordinating with metal ions, the formed metal complex catalyst can play a catalytic role in many chemical reactions. In some redox reactions or carbon-carbon bond formation reactions, it exhibits unique catalytic activity and selectivity, which can improve the reaction efficiency and reduce the severity of reaction conditions.
In the field of materials science, it can also play an important role. It can be used to prepare functional polymer materials. By introducing it into the polymer chain segment, the material is given specific properties, such as improving the solubility, thermal stability and electrical properties of the material. For example, in the preparation of conductive polymer materials, the introduction of 1% 2C3-bis (triethylamino) benzene may be able to optimize the electron transport properties of the materials and improve the electrical conductivity of the materials.
In addition, in the field of drug research and development, the substance may have certain biological activities due to its unique chemical structure or can be used as a modifying group of drug molecules, providing the possibility for the creation of new drugs.
To sum up, 1% 2C3-bis (triethylamino) benzene plays an indispensable role in the fields of organic synthesis, catalysis, materials science and drug development, and is of great significance to promote the development of related fields.
What are the physical properties of 1,3-bis (trifluoromethyl) benzene?
1% 2C3-bis (triethylamino) benzene, its physical properties are as follows:
The appearance of this substance is often colorless to light yellow liquid. Smell, there is a specific smell, but its taste is not pungent and intolerable, but has a certain uniqueness.
When it comes to the boiling point, under normal pressure, it is about a certain temperature range. This temperature is the critical value for the material to change from liquid to gaseous state, and has a key guiding effect on its separation and purification operations. The exact value of its boiling point varies slightly according to the fineness of the experimental conditions, but the approximate interval can be followed.
The melting point is also a specific value, which is the temperature limit for the material to change from solid to liquid state. Knowing the melting point is of great significance in determining its purity and morphology under a specific temperature environment.
Compared with water, its density has a specific specific gravity. This property is related to its floating or sinking state in liquid mixtures, and is an important consideration in chemical separation, extraction and other processes.
In terms of solubility, it shows good solubility in common organic solvents such as ethanol and ether. This is due to the interaction between the molecular structure and the organic solvent, so that the two can blend with each other. However, in water, its solubility is relatively limited, due to the difference between molecular polarity and water molecular polarity.
Refractive index is also one of its significant physical properties. When light passes through the substance, it is refracted according to a specific law. The value of this refractive index is like the unique optical fingerprint of the substance, which is an indispensable parameter in the fields of substance identification and purity detection.
In addition, the volatility of the substance is moderate, neither highly volatile and quickly dissipated, nor difficult to volatilize and long-lasting retention. This volatility has a far-reaching impact on the setting of storage and use environments.
What are the chemical properties of 1,3-bis (trifluoromethyl) benzene?
1,3-Bis (triethylamino) benzene is one of the organic compounds. Its physical properties are usually liquid at room temperature, with clear and transparent color and a slight special odor. It has good solubility in organic solvents, but poor solubility in water.
In terms of its chemical properties, the benzene ring in this compound is aromatic and stable, and can undergo electrophilic substitution reactions under specific conditions, such as halogenation, nitrification, and sulfonation. The triethylamino group connected to the benzene ring is the power supply group, which can increase the electron cloud density of the benzene ring, thereby enhancing the activity of the electrophilic substitution reaction of the benzene ring.
The triethylamino group itself is also significantly basic, and the nitrogen atom has lone pair electrons, which can react with acids to form corresponding salts. Due to its alkalinity, 1,3-bis (triethylamino) benzene is often used as a base in the field of organic synthesis to help neutralize the acid generated during the reaction and promote the forward progress of the reaction.
Furthermore, 1,3-bis (triethylamino) benzene can participate in a variety of organic reactions, such as nucleophilic substitution with halogenated hydrocarbons to form new carbon-nitrogen bonds. This property makes it widely used in pharmaceutical chemistry, materials science and other fields.
Due to its special chemical properties, 1,3-bis (triethylamino) benzene is a useful intermediate in organic synthesis. By skillful use of its chemical properties, chemists can create many organic compounds with novel structures and unique functions.
What are the preparation methods of 1,3-bis (trifluoromethyl) benzene?
The preparation method of 1% 2C3-bis (triethylamino) benzene is not detailed in ancient books, but it can be deduced according to the current chemical principles and the variation of ancient methods.
First, using benzene as a group, first make benzene and appropriate halogenated compounds, such as halogenated ethane, under the catalysis of alkali, and introduce halogenated ethyl groups by nucleophilic substitution. Although people in the past did not have the precise catalytic means of today, they can find natural alkalis, such as plant ash and other alkali-containing substances, at a suitable temperature and time, to promote their reaction.
Then, the resulting halogenated ethylbenzene is met with triethylamine. This step also requires mild conditions, or water can be used as a medium to warm the kettle, so that the nucleophilic substitution of the two occurs, the halogen atom leaves, and the nitrogen atom of triethylamine attacks nucleophilic attack, and then becomes 1% 2C3 -bis (triethylamino) benzene. At that time, although there was no precise temperature control and separation equipment, it was possible to separate the product according to the experience of heat, with the boiling, warm, cool state of water, and the ancient methods such as static stratification and filtration.
Or find another way, first react the triethylamine with appropriate reagents to activate the nitrogen atom and enhance its nucleophilicity. Natural acids, such as acetic acid, can be found to adjust their activity. Then react with benzene derivatives. Benzene derivatives may have been pre-introduced with easy-to-leave groups, so that the target product can also be obtained by nucleophilic substitution. When operating, pay attention to the reaction environment, avoid moisture and impurities, seal the jar, and observe the reaction process according to the time and climate. Only in time can the finished product of 1% 2C3-bis (triethylamino) benzene be obtained.
What are the precautions for storing and transporting 1,3-bis (trifluoromethyl) benzene?
For 1% 2C3-bis (triethylmethyl) benzene, various precautions are especially important during storage and transportation.
When storing, choose the first environment. It must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. This is because of its flammability, high temperature or near an open flame, it may lead to fire. And humid gas can easily damage its quality, so a dry environment is indispensable. In addition, it should be placed separately from oxidizing agents, acids and other substances. Due to the active chemical nature of the substance, contact with them is prone to chemical reactions, or serious accidents such as explosion and combustion.
The transportation process also needs to be cautious. Transportation vehicles should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment, just in case. During transportation, ensure that the container does not leak, collapse, fall, or damage. When driving, you should drive slowly and avoid violent actions such as sudden braking and sharp turns to prevent the container from colliding and damaging, resulting in material leakage. At the same time, transportation personnel must undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. And transportation vehicles should follow the prescribed route and do not stay near densely populated areas and important facilities to reduce the harm of accidents.
In conclusion, in the storage and transportation of 1% 2C3-bis (triethylmethyl) benzene, all aspects must be carefully followed, and relevant norms and requirements must be followed to ensure safety.