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1,3-Bis(Trifluoromethyl)-Benzene

1,3-Bis(Trifluoromethyl)-Benzene

Hongda Chemical

Specifications

HS Code

244123

Chemical Formula C8H4F6
Molar Mass 214.107 g/mol
Appearance Colorless liquid
Boiling Point 119 - 120 °C
Melting Point -28 °C
Density 1.435 g/cm³ at 25 °C
Vapor Pressure 12 mmHg at 25 °C
Flash Point 17 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Refractive Index 1.365 at 20 °C

As an accredited 1,3-Bis(Trifluoromethyl)-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 mL bottle of 1,3 - bis(trifluoromethyl) - benzene, well - sealed for chemical storage.
Storage 1,3 - bis(trifluoromethyl) - benzene should be stored in a cool, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Suitable storage temperatures typically range around ambient but avoid extreme temperature fluctuations.
Shipping 1,3 - bis(trifluoromethyl) - benzene is shipped in specialized, corrosion - resistant containers. Strict safety protocols are followed due to its chemical nature. Shipments are carefully monitored for temperature and handling to ensure safe transit.
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1,3-Bis(Trifluoromethyl)-Benzene 1,3-Bis(Trifluoromethyl)-Benzene
General Information
Historical Development
The historical development of 1,3-bis (trifluoromethyl) benzene has been considerable. In the past, organic chemistry was in full swing, and many wise men did not delve into fluoride. Catching up with scientific evolution, chemists worked hard to explore the properties of fluorinated compounds. In many explorations, 1,3-bis (trifluoromethyl) benzene gradually entered the field of vision. Early preparation was difficult, and the yield was low, which was only available in a few laboratories. However, scholars are reluctant to study, improve the process, and optimize the process. With the passage of time, the technology has advanced, and the preparation of this compound has gradually matured. It has emerged in the fields of medicine, materials, and other fields, and its application is increasingly widespread, adding a brilliant chapter to the development of chemistry.
Product Overview
1,3-Bis (trifluoromethyl) benzene is also an organic compound. It is a colorless and transparent liquid with a special odor. This substance has a wide range of uses in the field of organic synthesis, and can be used as an intermediary in the synthesis of medicines, pesticides and materials.
Because its molecular structure contains trifluoromethyl, it is endowed with unique physical and chemical properties. For example, it has good thermal and chemical stability, and can maintain its own structural stability in many chemical reaction environments. And in terms of solubility, it shows good solubility in common organic solvents, which is helpful for participating in various organic reactions.
On the synthesis path, it is often obtained by selecting suitable starting materials and catalysts through specific chemical reaction steps. With the advance of science and technology, the synthesis method has also been continuously optimized, aiming to increase yield, reduce costs, and reduce environmental pollution, making the production and application of this compound more efficient and green.
Physical & Chemical Properties
1,3-Bis (trifluoromethyl) benzene is an important compound in organic chemistry. Its physical and chemical properties are particularly critical. Looking at its physical properties, at room temperature, it is a colorless and transparent liquid with a special odor and strong volatility. The data of its boiling point and melting point are important parameters in chemical production and experimental operations. As for the chemical properties, because of its trifluoromethyl content, the compound has high chemical stability and electronegativity, and exhibits unique activities in many chemical reactions. It has different performances in nucleophilic substitution, electrophilic substitution and other reactions, providing a variety of paths for organic synthesis chemistry, and has broad application prospects in materials science, medicinal chemistry and other fields.
Technical Specifications & Labeling
Today there is a product named 1,3-bis (trifluoromethyl) benzene. It is my responsibility to study the technical specifications and identification (commodity parameters) of this product.
The preparation method of this 1,3-bis (trifluoromethyl) benzene requires fine rules. From the choice of raw materials, purity must be required, and the ratio between the millimeters must be checked. When reacting, temperature, pressure and other variables should be precisely controlled, such as trade-offs, and there should be no slight discrepancies.
As for one end of the logo, the product parameters contained in it, such as purity geometry and properties, should be clearly displayed. The purity needs to be high, and the properties must be in line with the established standards. Only in this way can we ensure the quality of this thing, which is beneficial to the user and non-destructive to the market. The importance of technical specifications and labels is related to the success or failure of this thing.
Preparation Method
The preparation method of 1,3-bis (trifluoromethyl) -benzene is related to the raw material and production process, reaction steps and catalytic mechanism, which is the key to chemical research.
To make this product, specific raw materials can be used. The compound containing the corresponding group is selected as the starting material, such as an aromatic hydrocarbon derivative, with its specific structure to start the reaction. In the production process, in a suitable reaction vessel, adjust the temperature, pressure and other conditions.
The reaction step first re-activates the raw material, and the activity is improved by pretreatment. Next, a specific reagent is introduced to make the two react according to a specific path. For example, catalytic addition, with the power of the catalyst, the reagent is added to a specific position of the raw material in a directional manner.
The catalytic mechanism is also critical. Choose the appropriate catalyst, which can reduce the activation energy of the reaction and promote the efficient progress of the reaction. The catalyst and the reactant form an active intermediate, guide the reaction in a predetermined direction, and improve the selectivity and yield of the product, so that 1,3-bis (trifluoromethyl) -benzene can be obtained.
Chemical Reactions & Modifications
Nowadays, there is a substance called 1,3-bis (trifluoromethyl) -benzene, which is often studied in chemical research. The chemical reaction is related to this substance, which is really the key. If its reaction characteristics can be well understood, it will be of great use in all kinds of synthesis.
In the past, it is common to investigate the reactions it participates in, and the rate and yield may not be good. The reason for this is that the reaction conditions are not suitable, or the catalyst is not suitable. In order to improve, we have carefully tried to change the temperature and pressure that are easier to react, and replace the catalytic agent.
Looking at the change, the temperature rises, although the reaction rate increases, there are many side reactions; the pressure changes, but the effect is not obvious. Under the new agent, the reaction rate is greatly increased, the yield is also significantly improved, and the side reactions are greatly reduced.
From this, it can be seen that chemical reactions and physical properties are not static. Only by studying carefully and seeking progress through change can we obtain its wonders. In the process of chemical research, it is gradually moving away and reaching a good state.
Synonyms & Product Names
1,3-Bis (trifluoromethyl) benzene, its congeners and trade names have been discussed since ancient times. The subtlety of cover chemistry, the substances are different, and the names are also changeable.
1,3-Bis (trifluoromethyl) benzene, or another name, such as the variant of trifluorobenzene, the name of its product, also varies according to the origin and use. In the field of chemical industry, if you want to know its accuracy, you must check the classics in detail and visit the Fang family.
In the past, chemistry was not developed, and the identification of substances relied on intuition. Today, science and technology are prosperous, and the molecular structure can be analyzed, but the name is mixed, which is still a difficulty. This 1,3-bis (trifluoromethyl) benzene has a similar name for its congener or according to its structure; the trade name is related to the needs of the market, or to its characteristics, or to its origin.
If you want to understand the details, you must study the essence of the scientific method to obtain the true meaning of the same thing and the trade name.
Safety & Operational Standards
1,3-Bis (trifluoromethyl) benzene, this material is special, related to safety and operating standards, and should not be ignored.
At the safe end, it is volatile, and the steam may be irritating to the respiratory tract, eyes and skin. If inhaled inadvertently, move quickly to a fresh place in the air. If the discomfort is not solved, seek medical attention immediately. If it touches the skin, rinse with plenty of water immediately; if it enters the eyes, it must also be rinsed with water quickly and seek medical treatment. Because of its flammability, in case of open flames and hot topics, there is a risk of explosion. When storing, store it in a cool and ventilated place, away from fire and heat sources, and store it separately from oxidants. Do not mix storage.
Talking about the operating specifications, in the laboratory, the operator must strictly wear protective equipment, such as protective glasses, gloves, and laboratory clothes, to prevent them from contacting the body. The operating site should be well ventilated, preferably in the fume hood, to prevent the accumulation of steam. When taking it, the action should be slow and beware of water sprinkling. After the experiment, the equipment used should be cleaned in time, and the residue should also be properly disposed of in accordance with regulations, and should not be discarded at will. In industrial production, the equipment should be well sealed and have a complete ventilation and exhaust gas treatment system. Operators must be professionally trained and familiar with the operation process and emergency methods. Regular maintenance of equipment to prevent leakage. In this way, it is possible to ensure the safety of the operation of 1,3-bis (trifluoromethyl) benzene and avoid disasters.
Application Area
1,3-Bis (trifluoromethyl) benzene, the field of its use can be explored. This compound is used in the field of medicine, or as the basis for the creation of new agents. Because of its special structure, it can specifically combine with various molecules in the body, help regulate physiological functions, and treat various diseases. In the field of materials, it can be used as a raw material for the synthesis of special polymers. The resulting material may have excellent chemical stability, heat resistance, etc., and is used in fine fields such as aerospace and electronics. And in the production of pesticides, it can also be used. Pesticides can be given unique insecticidal and bacteriostatic properties to protect crops for a bumper harvest. It is widely used, and it is waiting for our generation of chemical researchers to dig deep and expand it, so as to develop its endless potential and benefit the world.
Research & Development
Since modern times, chemical refinement has resulted in the emergence of various new substances. 1,3-Bis (Trifluoromethyl) -Benzene is an important item for us to study.
We scrutinize its properties and explore the method of its synthesis. At the beginning, the path was difficult, the raw materials were rare, and the reaction was also harsh. However, we have been unremitting, trying new regulations repeatedly, hoping to improve its yield and reduce its cost.
Looking at its application, it can be used in medicine and materials. Medicine, or can help the production of new drugs, to treat human diseases; the field of materials, or can create strange qualities, to meet all needs.
We should carry forward the ambitions of our predecessors, carry forward the past and open up the future, study this thing in depth, and hope that it will shine in the future and benefit the world, so as to promote the progress of chemistry and the prosperity of mankind.
Toxicity Research
Toxicity Study of 1,3-Bis (Trifluoromethyl) Benzene
We are chemical researchers who have been dedicated to the investigation of the toxicity of various chemical substances for a long time. Today, we focus on 1,3-bis (trifluoromethyl) benzene to investigate its toxicity in detail.
Experiments have shown that this substance has a certain effect on the tested organisms under specific conditions. In cell experiments, high concentrations of 1,3-bis (trifluoromethyl) benzene can reduce cell activity and change its morphology, or suggest that it interferes with cell physiological functions.
In animal experiments, after the test animals were exposed to this chemical, the functional indicators of some organs were abnormal. Changes in the activity of metabolic enzymes in the liver and the filtration function of the kidneys are also affected, indicating that 1,3-bis (trifluoromethyl) benzene has potential toxic effects on important organs of the body.
However, more in-depth studies are needed to clarify the exact toxicity mechanism. It is necessary to explore its metabolic pathways in vivo and its effects on molecular signaling pathways in order to provide a solid basis for a comprehensive understanding of the toxicity of 1,3-bis (trifluoromethyl) benzene.
Future Prospects
Today, there is a thing named 1,3-Bis (trifluoromethyl) benzene, which is like a shining star in our chemical research, illuminating the direction of the future. This material is unique, with both strange chemical activity and stable structure.
Looking at its future, the field of application is like a vast sea, waiting for us to set sail to explore. In the study of materials, it can give birth to new profiles with extraordinary characteristics to meet the needs of ever-changing times; in the road of medicine, or as the cornerstone of the development of special and good medicines, healing all kinds of diseases.
With the development of science and technology, we uphold the ambition of research, and hope to expand the unknown with wisdom and hard work. In the near future, 1,3-Bis (trifluoromethyl) benzene will shine brightly, adding luster to human well-being, becoming a strong driving force for future development, and expanding infinite possibilities.
Where to Buy 1,3-Bis(Trifluoromethyl)-Benzene in China?
As a trusted 1,3-Bis(Trifluoromethyl)-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Bis(Trifluoromethyl)-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-bis (trifluoromethyl) benzene?
1% 2C3-bis (triethyl) benzene has a wide range of uses. This substance is often a key raw material in the field of organic synthesis. Due to its structural characteristics, it can be derived from a variety of organic compounds through many chemical reactions, making great contributions to the fine chemical industry.
In the field of pharmaceutical chemistry, 1% 2C3-bis (triethyl) benzene also plays an important role. Because it has specific chemical activities and molecular configurations, or can participate in the construction of drug molecules, it provides an opportunity for the development of new drugs. By chemically modifying and modifying it, it is expected to create drugs with better efficacy and less side effects.
In the field of materials science, this compound can be used to prepare high-performance materials. For example, copolymerization with other monomers can improve the mechanical properties and thermal stability of materials. Due to its unique chemical structure, it can endow materials with special physical and chemical properties, suitable for high-end fields such as aerospace and electronic information.
Furthermore, 1% 2C3-bis (triethylmethyl) benzene is also used in dyes, fragrances and other industries. It can be used as an intermediate for the synthesis of specific dyes and fragrances to help prepare products with brilliant colors and unique aromas to meet the diverse needs of the market.
In conclusion, 1% 2C3-bis (triethylmethyl) benzene, with its special chemical structure, has shown important uses in many fields such as organic synthesis, medicine, materials, dyes and fragrances, and plays an important role in promoting the development of various related industries.
What are the physical properties of 1,3-bis (trifluoromethyl) benzene?
1% 2C3-Bis (triethoxypropyl) silicon, which has complex and diverse physical properties. Its shape is mostly colorless, transparent or yellowish liquid at room temperature, which is lighter and flows smoothly, just like smart water.
Looking at its solubility, it can be well miscible in many organic solvents such as toluene and ethanol, just like fish entering water and blending seamlessly. This property makes it easy to mix with other ingredients when preparing paints and adhesives, ensuring that the system is uniform and stable, just like a craftsman blending pigments, with uniform colors.
When it comes to boiling point, the value is quite high, and it needs to be hot to boil and convert into gas phase. This hot topic stability allows it to maintain its own structural stability in a high temperature environment and not easily decompose and deteriorate. Just like the rock, it is still as strong as ever after being roasted by fire.
Besides its chemical activity, the siloxane base is lively, like a lively and active child, and is easy to react with hydroxyl, carboxyl and other groups. With this characteristic, it can greatly change the surface properties of materials in the field of surface modification, such as imparting hydrophobic properties, so that water on its surface resembles water droplets on a lotus leaf, rolling and sliding.
Its hydrolysis cannot be ignored. When exposed to water, the siloxane group will slowly hydrolyze to form a silanol group, which can then be condensed and crosslinked. This process is like building a building block, gradually building a three-dimensional network structure, which greatly enhances the cohesion and mechanical properties of the material, making it more durable.
In short, 1% 2C3-bis (triethoxy propyl) silicon has unique physical properties and is important in many fields of chemical materials. It is like a master key, opening the door to many material modifications and applications.
Is the chemical properties of 1,3-bis (trifluoromethyl) benzene stable?
1% 2C3 -bis (triethylamino) benzene, its chemical properties are quite stable. Among this substance, the benzene ring is the core structure of stability, giving it considerable stability. The triethylamino group, although it has a certain activity, interacts with the benzene ring under conventional conditions, making the overall structure tend to be stable.
Looking at the chemical environment in which it is located, if it is at room temperature and pressure, and there is no strong oxidizing agent, strong reducing agent or strong acid and alkali, the substance can maintain a stable state and is not prone to spontaneous chemical reactions. Even when heated, it is difficult to have significant chemical changes without specific initiation conditions.
Furthermore, in terms of the intermolecular force, the intermolecular force is mainly van der Waals force, which is relatively weak. However, due to the regularity of the molecular structure, it maintains its own stability to a certain extent. However, in case of specific chemical reaction conditions, such as high temperature, high pressure and catalyst intervention, or when encountering matching reactants, its stability will also be damaged, and the molecular structure will undergo corresponding transformations.
In summary, 1% 2C3 -bis (triethylamino) benzene is chemically stable under normal conditions, but in specific extreme or suitable reaction situations, the stability is different.
What are the precautions in the synthesis of 1,3-bis (trifluoromethyl) benzene?
In the synthesis of 1% 2C3-di (triethoxy) silane, there are many things to pay attention to. First of all, pay attention to the purity and quality of the raw materials. If the raw materials are pure, the product is good, and impurities are prone to side reactions, which affect the yield and purity of the product. Therefore, when purchasing, it is necessary to strictly select raw material suppliers and check the various indicators of the raw materials in detail.
The reaction conditions are also crucial. The temperature needs to be precisely controlled. If it is too high, the reaction will be too fast and it will be prone to by-products; if it is too low, the reaction will be slow and take a long time. Taking common synthesis methods as an example, the temperature is often controlled in a specific range, such as [X] ° C - [X] ° C, depending on the selected reaction path and At the same time, the reaction time should not be underestimated. If the time is too short, the reaction will not be completed; if the time is too long, it will consume resources and may lead to adverse consequences such as product decomposition.
The choice and dosage of catalyst have a profound impact on the reaction. Suitable catalysts can greatly improve the reaction rate and selectivity. Different catalysts have different activities and selectivity, and should be carefully selected according to the reaction mechanism and expected products. The dosage must also be accurate. Too much or too little is not conducive to the reaction.
In addition, the cleaning and sealing of the reaction device cannot be ignored. If the device is not clean, residual impurities will interfere with the reaction; if the sealing is not good, the reactants or products are easy to evaporate and escape, which not only wastes raw materials, but also may cause safety During the synthesis process, the reaction process should also be closely monitored, and the reaction dynamics should be grasped in real time by means such as chromatographic analysis, so as to adjust the reaction conditions in time.
The post-treatment process is also critical, and the separation and purification of the product is related to the quality of the final product. Select appropriate separation methods, such as distillation, extraction, etc., to remove impurities and improve the purity of the product. In this way, the synthesis of 1% 2C3-bis (triethoxy) silane can be ensured smoothly, and high-quality products can be obtained.
What are the environmental effects of 1,3-bis (trifluoromethyl) benzene?
1% 2C3-bis (triethylamino) benzene has a complex environmental impact and needs to be analyzed in detail.
This substance may be in a volatile state in the air. When it evaporates, it may enter the atmospheric circulation and come into contact with various substances. If this substance evaporates near the ground, or causes changes in air quality, it will disturb people's respiratory health. If people inhale these volatile ingredients, it can cause throat discomfort, itchy nose and eyebrow, severe or respiratory diseases, such as asthma, cough, and even damage lung function.
As for the water environment, if 1% 2C3-bis (triethylamino) benzene flows into rivers, lakes and seas, it may dissolve into the water body, which is quite harmful to aquatic organisms. Aquatic plankton bear the brunt, or cause its physiological disorders, affecting the population reproduction. If fish live in waters containing this substance, or cause damage to their gills, affecting respiration, or accumulating in the body, passing through the food chain, and eventually endangering higher organisms, including humans. If people eat this contaminated fish, it may cause the accumulation of toxins in the body, causing various health problems.
In soil, this substance may affect the community structure of soil microorganisms. Soil microorganisms are essential for soil fertility and material circulation. The presence of 1% 2C3-bis (triethylamino) benzene may inhibit the growth of beneficial microorganisms, hinder the decomposition and transformation of organic matter in the soil, and cause soil fertility to decline. And it may penetrate into the ground, pollute groundwater, and affect the quality of groundwater resources.
In addition, 1% 2C3-bis (triethylamino) benzene may have certain chemical activities. Under specific environmental conditions, or react with other chemical substances to form new pollutants, and its impact on the environment is more complex and unpredictable. Therefore, when using and disposing of substances containing this substance, care should be taken to reduce its harm to the environment.