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1,3-Bis(Difluoromethoxy)Benzene

1,3-Bis(Difluoromethoxy)Benzene

Hongda Chemical

Specifications

HS Code

651586

Chemical Formula C8H6F4O2
Molar Mass 210.127 g/mol
Appearance Liquid (usually)
Boiling Point 170 - 172 °C
Density 1.34 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low
Flash Point 61 °C
Refractive Index 1.447 - 1.449

As an accredited 1,3-Bis(Difluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottles containing 1,3 - bis(difluoromethoxy)benzene, well - sealed.
Storage 1,3 - bis(difluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics, to prevent leakage and contamination.
Shipping 1,3 - bis(difluoromethoxy)benzene is shipped in accordance with chemical transport regulations. It's typically in sealed, corrosion - resistant containers to prevent leakage, and transported by specialized carriers ensuring safe handling.
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1,3-Bis(Difluoromethoxy)Benzene 1,3-Bis(Difluoromethoxy)Benzene
General Information
Historical Development
1,3-Bis (difluoromethoxy) benzene is also a product of chemistry. At the beginning of its development, the people did not know its wonders. At the beginning, there were few people who studied it, and the results were also sparse. However, as the years passed, the wise people gradually focused on its ability. Either because of its stable nature, or because of its wide range, it led to more and more research. What was explored in the past, or confined to the law, or trapped in the material, was unremitting. With the progress of technology, the material is good, the more refined the method is, and the amount of production is also increased. From little known to being used by the public, its journey has been tortuous, just like a river rushing, and finally it has become today's state. In the field of chemical industry, it gradually becomes important.
Product Overview
1,3-Bis (difluoromethoxy) benzene, an organic compound. It may be in the form of a colorless liquid with a special odor. In the field of organic synthesis, this compound has a wide range of uses.
Looking at its structure, on the benzene ring, the two and four positions are connected with difluoromethoxy groups. This unique structure gives it specific chemical properties. Because of its high electronegativity of fluorine atoms, the molecular polarity changes and the reactivity is also affected.
In the chemical industry, it is often used as an intermediate and participates in many organic reactions. With appropriate reaction conditions, it can react with many reagents such as substitution and addition to prepare various high-value-added fine chemicals. And in the field of materials science, it can be used to synthesize polymer materials with special properties. Due to the introduction of fluorine atoms, the weathering resistance and chemical stability of materials can be improved.
Physical & Chemical Properties
The physicochemical properties of 1,3-bis (difluoromethoxy) benzene are worth exploring. Looking at its properties, under room temperature, it may be a colorless and transparent liquid with a special odor. On its boiling point, it has been experimentally measured that it is about a certain temperature range, which is due to the force between molecules. Its density is also fixed, reflecting the degree of molecular compactness. In terms of solubility, in some organic solvents, it exhibits specific solubility characteristics, which is related to molecular polarity. In terms of chemical properties, it contains difluoromethoxy groups, or can participate in specific chemical reactions, such as nucleophilic substitution. This is the key to exploring the physicochemical properties of this substance, and provides a cornerstone for its further application and research.
Technical Specifications & Labeling
1,3-Bis (difluoromethoxy) benzene is also an organic compound. Technical specifications for its preparation, selection of the first raw materials. Choosing pure starting materials is a priority. The reaction conditions must also be carefully controlled. Temperature, pressure and amount of catalyst are all related to the quality and quantity of the product.
The standard of inspection is related to the purity and impurity limit. With precise instruments, such as chromatography, the purity must reach a specific value to be qualified. The type and content of impurities also need to be strictly limited to prevent affecting their performance. The specifications and labels (commodity parameters) of this product are the key to ensuring its application, and must be accurate to meet the needs of all parties.
Preparation Method
The method of making 1,3-bis (difluoromethoxy) benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First take an appropriate amount of raw materials, which need to be pure and compatible. In a special vessel, put it in a precise ratio. At the beginning, control the temperature in a suitable environment to allow it to blend slowly. Next, add a special catalyst to promote the reaction to speed up.
The reaction steps need to be careful and followed in sequence. At the beginning, the raw materials interact and gradually produce new substances. During the process, carefully observe the changes in temperature and pressure, and adjust them in a timely manner to ensure a smooth reaction. The catalytic mechanism is the key, and the catalyst can reduce the energy barrier of the reaction, increase the activity of molecules, and accelerate the synthesis.
After a multi-step reaction, the product is gradually formed. After purification by an exquisite method, the pure 1,3-bis (difluoromethoxy) benzene is obtained by removing impurities and storing essence. This method requires craftsmen to study carefully and abide by regulations before it can become a high-quality product.
Chemical Reactions & Modifications
Since modern times, chemistry has been refined. The study of 1,3-Bis (Difluoromethoxy) Benzene is related to chemical reaction and modification, which is quite important. We study this compound and see its reaction mechanism, which often remains to be investigated. The method of the past, the reaction may not be sufficient, the yield is not ideal, and the purity of the product also has room for improvement.
We thought deeply and wanted to improve it, so we started from the reaction conditions. Adjust the temperature and pressure, and screen the suitable catalyst. After repeated tests, it was found that moderate temperature rise can promote the reaction rate; a specific catalyst can make the reaction more selective and the product purity is also increased. And try to change the ratio of reactants to achieve a delicate balance, so that the reaction proceeds in the expected direction. After this improvement, the chemical properties of 1,3-Bis (Difluoromethoxy) Benzene were significantly optimized, the yield was improved, and the quality was also improved to a higher level, paving the way for its practical application.
Synonyms & Product Names
1,3-Bis (difluoromethoxy) benzene, which is particularly important in the field of chemical research. Its synonymous name, or bis (difluoromethoxy) m-xylene, is also known as special fluoroether benzene.
This substance is widely used in the field of organic synthesis. It can be used as an active intermediate to participate in the preparation of various complex compounds. Its unique structure, containing difluoromethoxy, gives the molecule special physical and chemical properties, such as high stability and unique reactivity.
In the fine chemical industry, this material can be used as a raw material to make high-end coatings, special plastics, and improve the performance of products. It has also emerged in the field of pharmaceutical research and development, or is a key structural fragment of innovative drugs, helping to develop new drug formulations. Therefore, the research and application of 1,3-bis (difluoromethoxy) benzene has broad prospects and is of great benefit to the development of chemical industries.
Safety & Operational Standards
1,3-Bis (difluoromethoxy) benzene is also a chemical product. In the way of our generation's chemical research, its safety and operating standards are of paramount importance and importance.
The preparation of this substance should be in a well-ventilated place. Because of its volatility, if it is gathered in the room, there is a risk of accidents. And the preparation equipment must be clean and dry to prevent impurities from disturbing the reaction and causing the product to be impure.
During operation, the amount of various reagents must be accurately weighed. The difference is very small, thousands of miles, the amount is inaccurate, the reaction may not meet expectations, and the quality of the product is also affected by it. When taking the reagent, do not touch it with your bare hands when using a suitable appliance. It may be irritating to cover it, and it will be too late to hurt the skin.
When reacting, the control of temperature and time is the key to success or failure. If the temperature is too high, or the reaction is excessive, the product will decompose; if the temperature is too low, the reaction will be slow and time-consuming. And the length of time also affects the yield and purity of the product. You must follow accurate records and experience and abide by its laws.
The product is available, and the storage is also exquisite. It should be placed in a cool, dry, and dark place, sealed and stored to prevent it from contacting with air, water vapor, etc., and causing it to deteriorate.
In the laboratory, keep safety regulations in mind. In the event of an accident, such as a fire or a leak, it is necessary to calm down and deal with it quickly according to the established policy to ensure the safety of everyone and protect the experimental equipment. In this way, the goodness of 1,3-bis (difluoromethoxy) benzene products can be obtained, and the road to research and development will be smooth.
Application Area
1,3-Bis (difluoromethoxy) benzene is also a chemical product. Its application field is quite wide. In the field of pharmaceutical creation, it may be a key raw material to help synthesize special agents, heal various diseases, and solve the suffering of the world. In the world of fragrance modulation, it may also play an important role, giving spices a unique fragrance and enhancing their elegance. Furthermore, in the process of high-end material preparation, it can be an important component to improve the performance of materials and make them suitable for special scenes. For example, to create a delicate medicinal fragrance, like an ancient recipe to find seclusion; to build tough materials, like gold and stone. This is the beauty of the application of 1,3-bis (difluoromethoxy) benzene, which adds brilliance to many fields, just like the stars shining at night.
Research & Development
1,3-Bis (difluoromethoxy) benzene is also a chemical substance. I have studied it for many years. At the beginning, explore its structure, analyze its properties, and understand its role in the reaction.
Study its synthesis method, try various paths, or gain or lose. After repeated adjustment, a better method can be obtained. Although the process is difficult, every progress is gratifying.
Looking at its application prospects, it can be used in the fields of medicine and materials. In medicine, new drugs may be formed; in materials, special materials may be created.
I will make unremitting efforts to develop the potential of this substance and contribute to the development of chemistry and the well-being of mankind.
Toxicity Research
1,3-Bis (difluoromethoxy) benzene is also a chemical product. It is quite important for toxicity research.
Today, this product is carefully investigated. Its molecular structure is unique, contains difluoromethoxy, or causes special chemical activity. The study of its toxicity is related to the health of organisms and environmental safety.
Through various experiments, explore its impact on organisms. In animal experiments, observe its physiological changes after ingestion, observe the appearance and behavior of organs. Also consider its degradation in the environment to prevent its accumulation and harm.
Although this product may have its uses in industry, toxicity research should not be ignored. It is necessary to carefully examine its potential hazards before it is possible to take safe measures to make this chemical product useful and harmless to the world.
Future Prospects
Fu 1,3 - Bis (Difluoromethoxy) Benzene This product has extraordinary potential in the field of our chemical research. Looking at the present, although some of its characteristics and production methods have been clarified, there is still a vast future for future development.
In the future, it is expected to shine in the road of pharmaceutical creation. Its unique structure may open up a new path for the research of new drugs. It can accurately fit specific targets, heal all kinds of diseases, and save patients from pain.
And in the field of materials science, it may also emerge. With exquisite design, it may become a new material with outstanding performance, which can be used in the fields of electronics and aviation to help make a leap in science and technology.
Although there may be thorns in the road ahead, we, the scientific researchers, should have the courage to explore and study diligently, hoping to develop the potential of 1,3-Bis (Difluoromethoxy) Benzene to the fullest, for the well-being of mankind, to draw a magnificent picture to welcome the future brilliant exhibition.
Where to Buy 1,3-Bis(Difluoromethoxy)Benzene in China?
As a trusted 1,3-Bis(Difluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3-Bis(Difluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3-bis (difluoromethoxy) benzene?
1,3-Bis (diethoxysilyl) benzene, this substance has a wide range of uses. In the construction field, it can be used as a raw material for sealants and binders. Because it contains ethoxysilane, it can chemically react with the surface of a variety of materials to form stable chemical bonds, enhance sealing and bonding effects, and make building structures more durable. In the coating industry, it is often used as an additive. After adding coatings, it can improve the performance of coatings, such as improved adhesion, weather resistance and wear resistance. When coatings are formed, ethoxysilane hydrolysis and condensation form a tight connection between the coating and the substrate, making the coating more firmly adhered, resistant to environmental erosion, and extending the service life. In the field of composites, 1,3-bis (diethoxysilyl) benzene acts as a coupling agent. It can improve the compatibility between inorganic fillers and organic substrates, making the two closely bonded, and improving the mechanical properties of composites, such as strength and toughness. For example, when used in glass fiber reinforced plastics, it can enhance the bonding force between glass fibers and resin matrices, and improve the comprehensive properties of composites. In the field of electronic materials, it can be used to make electronic packaging materials. With good chemical stability and electrical insulation, it ensures the stable operation of electronic components in complex environments and prevents components from being damaged by external factors. Overall, 1,3-bis (diethoxysilyl) benzene, with its unique chemical structure and properties, plays an important role in many industries, promoting the progress and development of materials technology in various fields.
What are the physical properties of 1,3-bis (difluoromethoxy) benzene?
1% 2C3 -bis (diethoxyformyl) benzene is a kind of organic compound. Its physical properties are quite unique, let me tell you in detail.
Looking at its properties, under normal temperature and pressure, it is mostly white to light yellow crystalline powder, which is easy to store and use. As for the melting point, it is about a specific range, generally between [X] ° C and [X] ° C. This melting point characteristic is of important reference value when identifying and purifying the substance.
Its solubility also has characteristics. In common organic solvents, such as ethanol and acetone, it has a certain solubility and can be dissolved into a uniform solution. However, in water, the solubility is very small and almost insoluble, which is determined by the characteristics of its molecular structure. The groups contained in the molecule make the interaction with water molecules weak.
The density of this substance is also one of its physical properties, about [X] g/cm ³. This density data is indispensable for material calculation in chemical production and related experiments.
Furthermore, its stability is quite good under certain conditions. In normal temperature and normal storage environment, it can maintain a relatively stable chemical structure, and is not prone to spontaneous decomposition or other chemical reactions. However, under certain conditions such as high temperature and strong oxidants, the stability will be affected, or chemical reactions will be triggered, resulting in changes in its structure and properties.
1% 2C3-bis (diethoxyformyl) benzene The physical properties are of great significance in many fields such as organic synthesis and materials science. Researchers and practitioners often plan experiments and design processes according to its properties, so as to realize its application value in different fields.
What are the synthesis methods of 1,3-bis (difluoromethoxy) benzene?
1% 2C3-bis (diethoxymethyl) benzene, an important intermediate for organic synthesis. The synthesis method can be followed in many ways, as follows.
First, benzaldehyde is used as the starting material and can be obtained by condensation reaction. First, benzaldehyde and triethyl orthoformate are catalyzed by acid to carry out condensation reaction. Among them, the acid can be p-toluenesulfonic acid or the like. When reacting, the temperature needs to be controlled in a suitable environment, usually in a mild heating state, between about 60-80 degrees Celsius. The two can be condensed to form a precursor of 1% 2C3-bis (diethoxymethyl) benzene, and then processed by post-treatment, such as extraction, distillation, etc., to obtain a pure product.
Second, m-xylene is used as the starting material. M-xylene is first chloromethylated to introduce chloromethyl. This reaction requires formaldehyde and hydrogen chloride as reagents, and anhydrous zinc chloride as the catalyst. After the successful introduction of chloromethyl, it undergoes a substitution reaction with sodium ethanol. Sodium ethanol has strong nucleophilicity and can replace chlorine atoms to obtain the structure of diethoxymethyl, resulting in 1% 2C3-bis (diethoxymethyl) benzene. In the reaction process, the conditions of chloromethylation are quite critical, and the temperature and the proportion of reagents need to be carefully regulated to avoid side reactions.
Third, resorcinol can also be synthesized from resorcinol. Resorcinol first reacts with chloromethyl methyl ether under basic conditions to form etherides. Then it reacts with ethanol under the action of acidic catalyst to exchange ether, thereby introducing diethoxy methyl to obtain the target product. In this synthesis route, the conversion of basic and acidic conditions and the control of reaction conditions are the keys to obtaining high-purity products.
Synthesis methods have their own advantages and disadvantages. With benzaldehyde as the raw material, the starting material is easy to obtain, but the reaction steps may be more complicated; the m-xylene route, although the steps are relatively simple, the chloromethylation reaction requires careful operation; the method of resorcinol, the raw material cost may be higher, but according to specific needs and raw materials, the appropriate method can be selected to synthesize 1% 2C3-bis (diethoxymethyl) benzene.
What are the precautions for storing and transporting 1,3-bis (difluoromethoxy) benzene?
1% 2C3-Bis (diethoxyformyl) benzene. When storing and transporting this substance, it is necessary to pay attention to many matters.
First, when storing, you should choose a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, high temperature and humid environment can easily cause deterioration. In case of hot summer, the warehouse temperature should be controlled within a specific range to prevent its properties from changing. In addition, it needs to be stored separately from oxidants, acids, alkalis and other substances. This is because of its active chemical properties. If it is mixed with the above substances, it may cause a chemical reaction, which may cause danger. Contact with strong oxidants may cause violent reactions and endanger safety.
Second, when transporting, the packaging must be tight and stable. It is necessary to choose packaging materials that meet relevant standards to ensure that they are not damaged and leaked due to vibration, collision and other factors during transportation. For example, it is packed in a special sealed container to prevent leakage. The transportation vehicle should also be clean and clean, and there should be no residual substances that react with the substance. And during transportation, it is necessary to strictly abide by transportation regulations to avoid long-term stays in densely populated areas. If the transportation route passes through the busy areas of the city or sensitive areas such as water sources, it is necessary to plan in advance and drive carefully to prevent unexpected accidents from seriously affecting the environment and personal safety. In addition, transportation personnel should also be familiar with the characteristics of the substance and emergency treatment methods. In case of emergencies such as leakage, they can respond quickly and correctly to minimize the harm.
What is the market outlook for 1,3-bis (difluoromethoxy) benzene?
1% 2C3 -bis (diethoxy methyl) benzene, in today's market, the prospect is still considerable.
This substance has a unique chemical structure and characteristics. In the field of chemical industry, it has a wide range of uses. Cover is often a key raw material in the field of organic synthesis because it contains diethoxy methyl groups, which endow it with specific reactivity and stability.
In the coating industry, it can be used as an excellent additive to help the coating improve film-forming performance, enhance adhesion, and make the coating more durable and decorative. The coatings market is large and continues to grow, and the demand for additives with excellent performance is also increasing. This provides a broad market space for 1% 2C3 -bis (diethoxymethyl) benzene.
It is also seen in the manufacture of pharmaceutical intermediates. Because it can participate in a variety of organic reactions, it provides an effective path for the synthesis of drug molecules with specific structures. The pharmaceutical industry is related to people's livelihood and is developing rapidly. There is a strong demand for various high-quality intermediates. With its characteristics, this substance has found opportunities for development in the pharmaceutical field.
Furthermore, with the progress of science and technology and the innovation of chemical technology, new application fields may continue to emerge. Developers are actively exploring its potential uses in cutting-edge fields such as new materials. If there is a breakthrough, it will open up a new market for this substance. Although competition still exists, it has a promising future by virtue of its unique advantages to gain a place in the market.