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1,3,5-Tris(Trifluoromethyl)Benzene

1,3,5-Tris(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

152205

Chemical Formula C9H3F9
Molar Mass 276.107 g/mol
Appearance Colorless liquid
Boiling Point 122 - 124 °C
Melting Point -32 °C
Density 1.585 g/mL at 25 °C
Vapor Pressure 13 hPa at 20 °C
Flash Point 24 °C
Solubility In Water Insoluble
Logp 5.17
Refractive Index 1.349 (20 °C)

As an accredited 1,3,5-Tris(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,3,5 - tris(trifluoromethyl)benzene in 500 - mL glass bottle, quantity: 1 unit.
Storage 1,3,5 - tris(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources, ignition sources, and oxidizing agents. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it in a dedicated chemical storage cabinet to prevent spills and potential hazards, and ensure proper labeling for easy identification.
Shipping 1,3,5 - tris(trifluoromethyl)benzene is shipped in tightly sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring safety during transit to prevent any leakage or hazard.
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1,3,5-Tris(Trifluoromethyl)Benzene 1,3,5-Tris(Trifluoromethyl)Benzene
General Information
Historical Development
1,3,5 - Tris (Trifluoromethyl) Benzene is an important compound in the field of organic chemistry. Going back to the past, the development of chemistry has a long history. Since the early scholars first got involved in organic synthesis, they have been unremitting in exploring the preparation of novel compounds.
In the early years, due to technical and cognitive limitations, the research progress of such compounds containing special functional groups was slow. However, with the development of science and technology, the analytical methods became more and more exquisite, and the synthesis technology also made breakthroughs. After repeated experiments and research, scholars finally found a method for synthesizing 1,3,5 - Tris (Trifluoromethyl) Benzene.
At first, the synthesis yield was low and the cost was high, and it was only studied in a small scale in the laboratory. After being improved and optimized by many chemists, the process gradually matured, and it was gradually able to achieve a certain scale of preparation. This compound has emerged in the fields of materials science, drug research and development, and injected new impetus into the development of related industries. Its historical evolution has witnessed the vigorous progress of the chemical discipline.
Product Overview
Today, there is a product named 1,3,5 - Tris (Trifluoromethyl) Benzene. It is an organic compound with a colorless liquid appearance and a special odor. The fluorine-containing group of this product gives it unique physical and chemical properties. Its chemical properties are stable and weather-resistant, and it can be used as a special reaction intermediate in many organic synthesis reactions. In the field of materials science, the fluorine-containing structure can improve the chemical resistance and low surface energy of materials. In industrial production, it is often prepared by a specific organic synthesis path. Although it has a wide range of uses, it is still necessary to pay attention to its safety when operating. Because of its some characteristics or impact on the environment and human body, it must be properly handled and used in accordance with regulations in order to maximize its function and avoid its harm.
Physical & Chemical Properties
1,3,5 - Tris (Trifluoromethyl) Benzene, its physical properties are worth exploring. This material is often a transparent liquid with a clear color, and has a special taste. Its boiling temperature is special, because the molecule contains trifluoromethyl, so that the molecular force is changed, and the boiling phase is generally different from benzene derivatives. Its density is also affected by the influence, and the ordinary benzene derivatives are high, which is due to the large amount of fluorine atoms. In terms of solubility, it has good solubility in soluble solutions, such as ether, chloroform, etc. Due to the principle of similar miscibility, its non-soluble phase is compatible. In terms of chemical properties, due to the absorptive properties of trifluoromethyl, the density of benzene clouds decreases, and the reactive activity of benzene substitution decreases.
Technical Specifications & Labeling
There is a thing today, named 1, 3, 5 - Tris (Trifluoromethyl) Benzene. The method of its production is related to technical specifications and identification (product parameters), which is the most important.
The production of this thing should first follow the exquisite skills. From the selection of materials, it must comply with its regulations, check its pure quality and quantity, and do not have a difference. During operation, the degree of temperature, pressure, and the length of time must be followed. This change is subtle and complex, and if you are not careful, all previous efforts will be wasted.
And its identification (product parameters) should not be ignored. Understand its shape, color, and taste, and remember its qualitative characteristics, such as the temperature of melting and boiling, density, and solubility. Marked on the object, the user can see at a glance, know its nature, know its use, and be correct. In this way, the best product of 1, 3, 5 - Tris (Trifluoromethyl) Benzene is in line with the requirements of technical specifications and identification (product parameters).
Preparation Method
The method of making 1, 3, 5 - Tris (Trifluoromethyl) Benzene is quite important. Prepare all materials first, and take appropriate raw materials. The nature and quality of this raw material should be carefully reviewed to ensure purity.
As for the art of production, the first step is the reaction. According to a specific order, make the raw materials touch each other, control their temperature and pressure, so that the reaction is smooth. When reacting, observe carefully, and do not make any mistakes.
also has a catalytic mechanism. Choosing the appropriate catalyst can promote the speed of the reaction and increase the amount of yield. When using it, clarify its dosage and timing to achieve the best effect.
In this way, 1, 3, 5-Tris (Trifluoromethyl) Benzene can be obtained. However, in the process, care should be taken and each step must be accurate in order to prepare this product.
Chemical Reactions & Modifications
Taste the way of chemical industry, emphasize change and change in time. Today there is 1, 3, 5 - Tris (Trifluoromethyl) Benzene, and its chemical reaction and modification are related to many fields.
View its reaction, or due to different conditions, the effect is different. In the context of catalysis, the structure of its molecules or the rate and direction of the reaction change. To seek its best effect, various factors must be studied in detail, including temperature, pressure, and catalyst.
As for modification, it is to make the substance more suitable. Or adjust its chemical activity to make it effective in special environments; or change its physical properties to enhance stability, solubility, etc. After repeated tests and observation of its changes, we can obtain a good strategy to make 1,3,5-Tris (Trifluoromethyl) Benzene shine in the chemical industry, so as to meet the needs and create more benefits.
Synonyms & Product Names
Today there is a thing named 1, 3, 5 - Tris (Trifluoromethyl) Benzene. Its same name also has the same name. This compound is used for special reasons. In the field of work, or raw materials, it can be used to help make it; in the context of scientific research, it is also necessary for exploring new knowledge.
However, the name of this thing is very common in the world. The name of the same is the convenience of scientific research and communication. The name of its product, which means business, each has its own characteristics. However, it does not refer to any name, but refers to this specific material. Those of us who study and use things need to understand their general characteristics in order to study and use them, so as to avoid confusion. Make the name of the same product familiar with the heart, in order to help the research and development of the next step.
Safety & Operational Standards
Specifications for the safety and operation of 1,3,5-tri (trifluoromethyl) benzene
1,3,5-tri (trifluoromethyl) benzene is an important substance in chemical research. Its special nature is related to safety and operation standards, and must not be ignored.
In terms of storage, choose a cool, dry and well-ventilated place. Because it has a certain volatility, if stored in a hot and humid place, or cause volatilization to increase, and may react with certain components in the air, it should be avoided. Reservoirs must also be carefully selected, and they must be resistant to corrosion to prevent leakage.
As for the operation, the experimenter must be fully armed. Wear protective clothing to prevent it from contaminating the skin; wear special gloves on your hands to prevent it from penetrating; cover your eyes with goggles to protect your eyes from damage. Operating environment When there is a good ventilation device to drain volatile gas in time to prevent it from accumulating and causing danger.
If a leak unfortunately occurs, don't panic. First, evacuate the surrounding people quickly and set up a warning area to prevent unrelated people from approaching. Then, according to the amount of leakage, choose the appropriate method to deal with it. When the amount is small, it can be adsorbed with inert materials, such as vermiculite, sand, etc., and disposed of properly after collection. If the amount is large, a professional team needs to recycle it with special equipment to ensure environmental safety.
Furthermore, after use, its residues and waste must not be discarded at will. When in accordance with the regulations of chemical waste treatment, classified storage, unified disposal by professional institutions, so as not to pollute the environment and endanger all living beings.
In short, although 1,3,5-tri (trifluoromethyl) benzene is beneficial for scientific research, its safety and operating standards are of paramount importance. Researchers should always keep in mind that they cannot slack off.
Application Area
1,3,5-tris (trifluoromethyl) benzene is also a wonderful chemical. Its application field is particularly wide. In the field of pharmaceutical research and development, it is often used as a key intermediate to assist in the research of pharmaceutical power and improve the performance of good medicines. In materials science, it is also indispensable. Based on it, materials with specific properties can be made, or have excellent weather resistance and anti-corrosion, and can stick to their quality in extreme environments. In the electronics industry, it can be supplemented by high-end electronic components to increase their performance. Although this chemical material is small, it has extraordinary uses in many fields. It is actually a treasure of scientific research and an important tool to promote the progress of various industries.
Research & Development
I am committed to the research of 1,3,5 - Tris (Trifluoromethyl) Benzene. This substance has unique properties and has many potential applications. At the beginning, I explored the method of its synthesis, and after repeated attempts and study of ancient books, I finally found an effective path. Although the synthesis process is difficult, precise temperature control and selection of appropriate reagents are required, but unremitting efforts will eventually pay off.
Then explore its characteristics and find that under specific conditions, its stability and reactivity are characteristic. Based on this, thinking about its application prospects in the field of materials, it is expected to develop new high-performance materials. I also work with my colleagues to study and exchange experiences, hoping to further expand its application range, promote this substance from research to practical application, realize its value, and contribute to the development of academia and industry.
Toxicity Research
Taste the things in the world, and those who harm people. The study of its toxicity is related to the safety of people's livelihood. In this sentence, the study of toxicity of 1, 3, 5 - Tris (Trifluoromethyl) Benzene is very important.
Observe this substance, its molecular structure is unique, and it contains trifluoromethyl. Although it may be useful in some chemical fields, the risk of toxicity cannot be ignored. To understand its toxicity, we should use scientific methods to test various organisms, observe its physiological changes, and observe its pathological signs.
Or at the cellular level, explore its effects on cell growth and metabolism; or in animals, study its effects on organ function and behavior. After many experiments, detailed data, and careful analysis, the strength of its toxicity and the mechanism of action can be clarified.
The study of toxicity is not an overnight effort, and it must be persevered and treated strictly in order to obtain an accurate theory. When using this product for the world, it can avoid harm and profit, protect the health of life, and protect the tranquility of the environment.
Future Prospects
Today, this 1,3,5 - Tris (Trifluoromethyl) Benzene has extraordinary potential. Although the current world's understanding of it is still shallow, I firmly believe that in the future, it will shine. Its unique structure may lead to the discovery of new chemical reaction paths, and in the field of materials science, it can lead to the creation of high-performance materials beyond imagination. And in medicinal chemistry, it may be a key element in the creation of new drugs with special effects. Although the road ahead is long, it is an opportunity for future development. With advanced scientific research and skilled technology, the potential of this material will be fully released, opening up a bright road for human well-being and creating a brilliant future.
Where to Buy 1,3,5-Tris(Trifluoromethyl)Benzene in China?
As a trusted 1,3,5-Tris(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,3,5-Tris(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,3,5-tris (trifluoromethyl) benzene?
1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%A6%82%E4%B8%8B%EF%BC%9A
This compound is often used as a key intermediate in the synthesis of a variety of drug molecules with specific biological activities in the field of medicinal chemistry. Due to its unique chemical structure, it can interact with specific targets in organisms, helping to develop innovative drugs for the treatment of various diseases such as inflammation and tumors.
In the field of materials science, 1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84 special structure endows it with potential photoelectric properties. It can be used to prepare new organic photoelectric materials, such as organic Light Emitting Diode (OLED), organic solar cells, etc., which are expected to improve the photoelectric conversion efficiency and stability of these materials.
In the field of organic synthetic chemistry, it is an extremely important building block. With its three specific sites of active groups, complex organic molecular structures can be constructed through a variety of organic reactions, such as substitution reactions, addition reactions, etc., providing organic synthesis chemists with rich strategies and possibilities to help expand the structural diversity of organic compounds and promote the development and innovation of organic synthetic chemistry.
In short, 1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84 plays an indispensable role in many important scientific fields, and is of key significance to the progress of scientific research and the expansion of practical applications in related fields.
What are the physical properties of 1,3,5-tris (trifluoromethyl) benzene?
1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%E6%89%80%E8%BF%B0:
The outer surface of this compound is often black to blue, with a special smell. Its melting temperature is low, around -60 ° C, which makes it liquid in normal environments. The boiling temperature is high, probably around 200-220 ° C. This characteristic makes it able to maintain the physical stability of the phase at a certain degree of temperature.
In terms of density, the 1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84 density is slightly higher than that of water, < 1.0-1.1 g/cm ³, which means that it will sink in water. In terms of solubility, the compound is soluble in water, and it is soluble in water, such as ethanol, ether, etc. This is because it is soluble. The molecular force is more compatible, and it conforms to the principle of similar miscibility.
Its chemical properties are low, and it is not easy to quickly dissipate under normal conditions. In addition, the chemical properties have a certain degree of certainty, and in general conditions, the chemical properties are determined, and it is not easy to produce strong reactions. However, in the presence of specific materials, such as high temperature, acid, acid or catalyst, it may also lead to chemical reactions and exhibit different chemical activities. In addition, the physical nature of 1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF makes it have a specific value in multiple domains, and also lays the foundation for its chemical reactions.
Is 1,3,5-tris (trifluoromethyl) benzene chemically stable?
1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%9D%A6%E7%A8%B3%E5%AE%9A%E4%B9%8B%E7%89%A9. Among this substance, its molecular structure is unique, and the structure of tri (triethoxy methyl) benzene makes its chemical activity subtle.
From the perspective of chemical bonds, the benzene ring is a stable conjugated system, and the triethoxy methyl group connected to it is connected to the benzene ring by a carbon-oxygen bond. This carbon-oxygen bond has a certain polarity, resulting in different electron cloud distributions. However, due to the conjugation effect of the benzene ring, its chemical stability can still be preserved.
In common chemical environments, if the temperature does not reach a certain threshold and there is no strong chemical agent intervention, this substance can maintain a relatively stable state. It has a certain tolerance to the general weak acid-base environment, just like the city wall to resist the invasion of ordinary wind and rain.
When encountering strong oxidants, the carbon-hydrogen bonds on the ethoxy methyl group can be oxidized or cause structural changes. In the case of high temperature and the presence of special catalysts, the substituents on the benzene ring may undergo reactions such as rearrangement, and the stability will be destroyed.
In summary, 1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF most common conditions, the chemical properties are relatively stable, but in extreme or special chemical environments, the stability may be challenged.
What are the methods for synthesizing 1,3,5-tris (trifluoromethyl) benzene?
1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84%E5%90%88%E6%88%90%E6%96%B9%E6%B3%95%E6%9C%89%E4%B8%8B%E5%88%97%E5%87%A0%E7%A7%8D%EF%BC%9A
- **%E4%BB%A5%E4%B8%89%E6%B0%9F%E7%94%B2%E9%85%8D%E4%BD%93%E4%B8%BA%E5%8E%9F%E6%9D%90%E7%9A%84%E6%96%B9%E6%B3%95**
- **%E5%85%88%E5%88%9B%E5%BB%BA%E4%B8%89%E6%B0%9F%E7%94%B2%E7%9A%84%E5%9F%BA%E7%A1%80%E5%8D%95%E5%85%83**: The Grignard reagent can be prepared by the reaction of halogenated ethane and magnesium in anhydrous ether, such as $C_2H_5Br + Mg\ xrightarrow [] {anhydrous ether} C_2H_5MgBr $. The Grignard reagent can be reacted with formaldehyde to introduce a hydroxyethyl group, and then the ethanol derivative is obtained by subsequent treatment, and then the halogenated ethanol derivative is obtained by halogenation reaction. After that, the halogenated ethanol derivative can be reacted with magnesium to obtain a new Grignard reagent, and then reacted with ethylene oxide to increase the carbon chain and introduce suitable functional groups. After multi-step reaction treatment, a compound containing three hydroxyethyl groups is obtained.
- **%E7%94%A8%E5%85%B6%E4%B8%8E%E8%8B%AF%E9%85%8D%E4%BD%93%E5%8F%8D%E5%BA%94**: Under suitable reaction conditions, such as alkali catalysis, the obtained compound containing three hydroxyethyl groups undergoes condensation reaction with benzaldehyde or its derivatives. The base can capture the active hydrogen in the compound to form carbon negative ions, and then undergo nucleophilic addition reaction with the carbonyl group of benzaldehyde. After dehydration and other steps, the final 1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF is formed.
- **%E4%BB%A5%E5%85%B6%E4%BB%96%E7%94%B2%E5%9F%BA%E5%8D%95%E5%85%83%E5%88%9B%E5%BB%BA%E5%90%8E%E7%BB%84%E5%90%88%E7%9A%84%E6%96%B9%E6%B3%95**
- **%E9%80%9A%E8%BF%87%E7%94%B2%E5%9F%BA%E5%8D%95%E5%85%83%E7%9A%84%E5%8F%8D%E5%BA%94%E6%9E%84%E5%BB%BA%E9%93%BE%E6%AE%B5**: Halogenated methane is used as the starting material and reacts with metal zinc to form organozinc reagents, such as $CH_3I + Zn\ xrightarrow [] {suitable conditions} CH_3ZnI $. The organozinc reagent reacts with carbonyl-containing compounds to grow carbon chains. Through a multi-step similar reaction, a suitable carbon chain structure containing three ethyl groups is gradually constructed.
- **%E8%8B%AF%E7%9A%84%E5%90%88%E6%88%90%E4%B8%8E%E7%BB%93%E5%90%88**: The constructed carbon chain structure containing three ethyl groups is reacted with the benzene ring under suitable conditions. For example, under the catalysis of Lewis acid, through the Fu-gram reaction, etc., the carbon chain structure is connected to the benzene ring, and after appropriate functional group transformation and modification, the final 1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF is obtained.
What are the precautions for storing and transporting 1,3,5-tris (trifluoromethyl) benzene?
1%2C3%2C5-%E4%B8%89%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E8%80%85 are organic compounds, and many matters need to be carefully paid attention to during storage and transportation.
Its chemical properties are lively, and it is easy to cause combustion or even explosion when exposed to heat, open flame or oxidant. Therefore, when storing, it should be placed in a cool and ventilated warehouse, away from fire and heat sources, and stored separately from oxidants and acids, and must not be mixed. The lighting, ventilation and other facilities of the warehouse must be explosion-proof. The switch should be located outside the warehouse, and there should be corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment.
When transporting, ensure that the container does not leak, collapse, fall or damage. The transportation vehicle should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. Summer transportation should be carried out in the morning and evening to avoid sun exposure. Road transportation should be carried out according to the specified route, and do not stop in residential areas and densely populated areas. When transporting by rail, it is forbidden to slip.
In addition, this compound may have certain toxicity and irritation, which can cause harm to human health. Storage and transportation personnel should take protective measures, such as wearing protective gloves, masks, goggles, etc., to prevent contact and inhalation. In the event of a leak, personnel from the contaminated area of the leak should be quickly evacuated to a safe area and quarantined to strictly restrict access. Emergency personnel must wear protective equipment and do not directly contact the leak. When a small amount of leakage occurs, it can be absorbed by inert materials such as sand and vermiculite. When a large amount of leakage occurs, a dike is built or a pit is dug for containment, covered with foam to reduce steam hazards, and then transferred to a tanker or a special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal.