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1,3,5-Trifluorobenzene

1,3,5-Trifluorobenzene

Hongda Chemical

    Specifications

    HS Code

    796225

    Chemical Formula C6H3F3
    Molar Mass 132.08 g/mol
    Appearance Colorless liquid
    Odor Characteristic
    Density 1.247 g/cm³ (at 20 °C)
    Boiling Point 89 - 91 °C
    Melting Point -48 °C
    Flash Point -1 °C
    Solubility In Water Insoluble
    Vapor Pressure 22.6 kPa (at 25 °C)
    Logp 3.17
    Refractive Index 1.399 (at 20 °C)

    As an accredited 1,3,5-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 mL of 1,3,5 - trifluorobenzene in a sealed, chemically - resistant glass bottle.
    Storage 1,3,5 - Trifluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and ignition points. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances. Use storage facilities compliant with chemical safety regulations to ensure safe containment.
    Shipping 1,3,5 - Trifluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported under regulated conditions, avoiding heat and ignition sources, ensuring safe transit due to its flammable and potentially hazardous nature.
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    1,3,5-Trifluorobenzene 1,3,5-Trifluorobenzene
    General Information
    Historical Development
    1,3,5-Trifluorobenzene is also a chemical product. The beginning of its discovery depends on the research of various sages. In the past, the public worked in the field of chemistry, searching up and down, and working hard to get this product.
    At the beginning, the preparation method was simple and clumsy, and the quality and quantity of the obtained product were not perfect. However, the researchers are determined and have not been slack. As time goes by, the technology is new, and the preparation method is becoming more and more refined. The precision of the instrument, the selection of materials, and the fineness of the steps are not comparable to the past.
    Today, 1,3,5-trifluorobenzene is useful in various fields. The path of its development, from simple to complex, from micro to the first, is really the effort of the researchers, the condensation of wisdom, and adds a brilliant chapter to the history of chemistry.
    Product Overview
    There is a substance today, named 1,3,5 - Trifluorobenzene. It is an organic compound with a unique structure. This substance is cleverly combined from carbon, hydrogen and fluorine elements. On the benzene ring, three hydrogen atoms are replaced by fluorine atoms, so this special structure is formed.
    Looking at its physical properties, it is mostly liquid at room temperature, volatile, and has a special taste. As for chemical properties, due to the existence of fluorine atoms, its activity is different from that of ordinary substances, and it can play a key role in many organic reactions.
    This compound has a wide range of uses in the chemical industry. It can be used as a raw material for the synthesis of special materials, and it has also made significant contributions to the research and development of medicine, helping to create new types of drugs. Therefore, although 1, 3, 5 - Trifluorobenzene is small, it has an extraordinary effect in the world of chemistry. It is important for our scientific researchers to explore it and hope to find more wonders for the well-being of mankind.
    Physical & Chemical Properties
    1,3,5 - Trifluorobenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, it is a colorless liquid at room temperature and pressure, with a special odor. Its boiling point is about 87-88 ° C, the melting point is -27 ° C, and the density is slightly smaller than that of water, about 0.99g/cm ³. It has little solubility in water, but it can be miscible with most organic solvents.
    Regarding chemical properties, the electron cloud density of the benzene ring of this compound changes due to the presence of fluorine atoms. The strong electron-absorbing effect of fluorine atoms reduces the electron cloud density of the benzene ring, resulting in lower electrophilic substitution reaction activity than benzene. However, under certain conditions, electrophilic substitution reactions such as halogenation, nitrification, and sulfonation can still occur, and the substitution check point is affected by the localization effect of fluorine atoms. These physicochemical properties are widely used in organic synthesis, drug research and development, and are important raw materials and intermediates for many chemical reactions.
    Technical Specifications & Labeling
    1,3,5-Trifluorobenzene is also an organic compound. The technique of its preparation is related to the subtlety of chemical industry.
    At the beginning of the technique, one must pay attention to the quality of the raw materials. The materials used should be of high accuracy, free of impurities and pure. The process of its preparation may involve chemical reactions, such as halogenation and substitution. During the reaction, the control of temperature and pressure is crucial. If the temperature is high, it will cause rapid disease, but it will not cause side effects; if the temperature is low, it will slow down, or the yield will drop. The same is true for the pressure, and it should be adjusted to the right place.
    As for the identification of the product, with modern instruments, such as chromatography and spectroscopy, its structure and purity can be refined. Looking at its peak shape and wavenumber, we can know the conformation and bonding of molecules. The determination of purity is related to the quality of commercial use. Impurities are inferior if they are many, and purity is excellent if they are high. According to this technique and labeling rules, good products can be obtained 1,3,5-trifluorobenzene to meet the needs of industry and scientific research.
    Preparation Method
    The method of making 1,3,5-trifluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often fluorinated compounds and related aromatic hydrocarbons. First, the aromatic hydrocarbons are mixed with specific fluorine-containing reagents in an appropriate ratio, and the reaction is carried out in a reaction kettle at a precise temperature and pressure for a specific time.
    At the beginning of the reaction step, the two interact under specific conditions to initiate chemical changes. Or through substitution and addition, it gradually becomes an intermediate product. Then, the intermediate product is converted again, and after a series of complex reactions, 1,3,5-trifluorobenzene is finally obtained.
    The catalytic mechanism is also the key. High-efficiency catalysts are often introduced to reduce the reaction energy barrier, promote the reaction rate, and increase the yield. This catalyst precisely regulates the reaction path, making the reaction progress in the expected direction and inhibiting the generation of side reactions. In this way, through raw material selection, exquisite process, orderly reaction steps and suitable catalytic mechanism, the excellent product of 1,3,5-trifluorobenzene can be obtained.
    Chemical Reactions & Modifications
    Today, we have studied 1, 3, 5 - Trifluorobenzene. We have carefully studied the chemical reaction and modification. The way of its reaction is related to many chemical principles. When this substance participates in the reaction, the fracture and formation of chemical bonds are in accordance with chemical laws.
    In order to find a way to modify it, we explore various conditions. Change the temperature to observe the difference in the reaction rate; or change the catalyst to observe the difference in the product. After repeated tests, it is known that if the temperature increases, the reaction rate may increase, but if it is too high, the product may change. The choice of catalyst is also crucial, and the appropriate agent can promote the reaction to a beneficial direction.
    After many efforts, the chemical reaction and modification of 1,3,5-Trifluorobenzene have gradually gained. It is expected that in the future, it will be more rational and make good use of it, which will contribute to the chemical industry.
    Synonyms & Product Names
    1,3,5-Trifluorobenzene is also a chemical product. In today's world, this substance has a wide range of uses, or is used in various chemical syntheses to form exquisite products. Its synonymous name, or another way of saying it, refers to all of them.
    Looking at the past, although it is not as clear as it is today, there are still related explorations. In the past, the family has gradually come to know the nature and use of things. This 1,3,5-trifluorobenzene, although its name is new, its quality may have existed in the field of chemical industry for a long time.
    The name of its commodity has also changed with the world. The name of the past may have been replaced by the different name of the present. However, it is all the same thing. Today's craftsmen and scholars study its nature and strive to develop their greatest abilities in industry and scientific research to help make things prosperous.
    Safety & Operational Standards
    1,3,5-Trifluorobenzene is also a chemical product. Safety and operating standards are of paramount importance during experimentation and production.
    It is lively and dangerous to a certain extent. To ensure safety, in the laboratory, it should be placed in a well-ventilated place. Operators must wear protective gear, such as gas masks, protective gloves, protective clothing, etc., to prevent its gas and liquid from touching the skin and respiratory tract.
    When taking it, the action should be slow and steady, and the equipment and method should be taken according to accurate measurement. Do not handle it with your bare hands, and do not make the equipment unclean and cause pollution.
    When storing, it should be in a cool, dry and ventilated place, away from fire and heat sources, and separated from oxidants, reducing agents and other foreign substances to prevent violent reactions.
    During the reaction process, close attention should be paid to changes in temperature, pressure and other conditions. If the temperature is too high, it may cause an out-of-control reaction; abnormal pressure may also cause the container to rupture. In case of emergencies, such as leaks, when evacuating personnel immediately, turn on ventilation equipment, and collect and deal with leaks in a professional way, do not panic.
    In the production process, equipment must be regularly inspected and maintained to prevent aging and damage and leakage. Operating procedures, when strictly formulated and implemented, each step has a fixed method and cannot be changed at will. In this way, we can ensure safety in the research and production of 1,3,5-trifluorobenzene, so that everything goes smoothly and achieves the desired goals without the risk of accidents.
    Application Area
    1,3,5-Trifluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to assist in the creation of new drugs, or involved in the research and development of antibacterial and anti-cancer drugs. With its unique chemical structure, the drug has better activity and selectivity.
    In materials science, it can be a raw material for the synthesis of special functional materials. If high-performance polymers are prepared, such polymers may have excellent heat resistance and chemical corrosion resistance, and can be used in high-end fields such as aerospace and electronics.
    In the development of pesticides, 1,3,5-trifluorobenzene can also be used. It can help develop high-efficiency and low-toxicity pesticides, improve the resistance of crops to pests and diseases, ensure a bumper agricultural harvest, and reduce environmental pollution. All of these can be seen in the important value of the application of 1,3,5-trifluorobenzene in various fields.
    Research & Development
    In recent years, Yu dedicated himself to the research of 1,3,5 - Trifluorobenzene. This material is special and has great prospects in various fields. At first, analyze its structure, explore its physicochemical properties, and examine the reaction mechanism in detail.
    During the experiment, many difficulties were encountered. The purity of raw materials and the control of conditions all need to be fine. However, Yu and colleagues are determined to try again and again, and finally get the best method. Optimize the process, improve its yield, and improve its quality.
    Today 1,3,5 - Trifluorobenzene has been gradually used in medicine, materials and other industries, with significant efficacy. Looking at its development, the prospect is vast. Yu and others will also continue to study and expand its new applications, with the aim of advancing the industry and promoting the prosperity of the world. They will do their best to promote its growth in more fields and create new trends.
    Toxicity Research
    "On the Toxicity of 1,3,5-Trifluorobenzene"
    The toxicity of 1,3,5-trifluorobenzene is related to people's health and cannot be ignored. Observe its properties, colorless liquid, pungent smell.
    According to various methods, if inhaled or touched by the skin in the animal body, there is a bad response. Inhaled, it can cause respiratory diseases, lung and lobes are invaded; when touched by the skin, it can make the skin red, swollen and itchy.
    The reason is that when this substance enters the body, it can disturb the normal flow of cells and disrupt the order of metabolism. Or due to the characteristics of fluoride, it will react with various substances in the body and cause damage to the function.
    Although the toxicity is known today, in the long run, further research is needed to clarify the degree of harm and find solutions to ensure that people are born without danger and promote the stability of chemical industry.
    Future Prospects
    1,3,5 - Trifluorobenzene is a strange substance. Looking at it at the moment, although it has not yet shown extraordinary capabilities, our generation of chemical researchers can see the bright future in it.
    This object has a unique structure, and the arrangement of fluorine atoms hides mysteries. At present, or just an exquisite research object in the laboratory, I am convinced that with time, it will shine.
    In the field of materials, 1,3,5 - Trifluorobenzene may give rise to new types of polymeric materials. The properties of its fluorine atoms can give materials excellent weather resistance and corrosion resistance, making it suitable for harsh environments, such as deep sea and extreme cold places.
    Furthermore, in pharmaceutical chemistry, it can be used as a key synthetic building block. Based on it, specific drug molecules can be constructed to overcome difficult diseases and seek well-being for human health.
    Although there may be thorns in the future, we researchers should have great ambitions and explore unremitting. We firmly believe that the future of 1,3,5 - Trifluorobenzene will be like the dawn of dawn, illuminating many fields and adding new color to the world.
    Where to Buy 1,3,5-Trifluorobenzene in China?
    As a trusted 1,3,5-Trifluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,3,5-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,3,5-trifluorobenzene?
    1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF, that is, 1,3,5-trimethylbenzene, its main uses are as follows:
    1,3,5-trimethylbenzene is a crucial organic chemical raw material. First, in the field of synthetic resins, it can be used as a raw material for the preparation of specific high-performance resins. Gein 1,3,5-trimethylbenzene has a unique chemical structure, which is used as a starting material. After a series of delicate chemical reactions, it can synthesize resins with excellent properties, such as high temperature resistance and chemical corrosion resistance. It is very useful in aerospace, high-end electronic equipment and other fields that require strict material properties.
    Second, in the manufacture of fine chemical products, 1,3,5-trimethylbenzene is also an indispensable basic raw material. Through the various organic synthesis reactions it participates in, a variety of fine chemicals can be prepared, such as fragrances, pharmaceutical intermediates, etc. Taking fragrances as an example, through chemical modification of 1,3,5-trimethylbenzene, fragrance components with unique aromas can be obtained, which can be used in perfumes, cosmetics and other products to add to the charm of the product. In the synthesis of pharmaceutical intermediates, compounds derived from 1,3,5-trimethylbenzene can provide key structural fragments for the synthesis of many drugs and help the development and production of new drugs.
    Third, 1,3,5-trimethylbenzene can still be used as an excellent solvent. Because of its good solubility to many organic compounds, and certain chemical stability and volatility, it is widely used in coatings, inks and other industries. As a solvent in coatings, it can effectively adjust the viscosity and drying speed of coatings, making it easier for coatings to be evenly coated during construction and forming high-quality coatings; in the ink industry, as a solvent, it can ensure good printing performance of inks, making printing patterns clear and bright colors.
    In summary, 1,3,5-trimethylbenzene plays an irreplaceable role in many fields such as organic synthesis, fine chemicals and solvents due to its unique chemical properties, which is of great significance to promote the development of modern industry.
    What are the physical properties of 1,3,5-trifluorobenzene?
    1,3,5-Trimethylbenzene, also known as m-trimethylbenzene, is an aromatic organic compound. Its physical properties are quite unique, as detailed below:
    Looking at its properties, at room temperature and pressure, 1,3,5-trimethylbenzene is a colorless and transparent liquid, with a pure texture and no impurities visible to the naked eye. Its odor is specific and aromatic. Although this aromatic gas is not pungent, it is quite rich and can be easily detected in the air.
    Regarding the boiling point, the boiling point of 1,3,5-trimethylbenzene is about 164 ° C to 165 ° C. The boiling point is the critical temperature at which a substance changes from liquid to gaseous. At this temperature, the molecules of 1,3,5-trimethylbenzene are sufficiently energized to break free from the shackles of the liquid phase and escape into the gas phase.
    As for the melting point, it is about -44.7 ° C. The melting point is the temperature limit for a substance to change from a solid state to a liquid state. When the temperature drops below the melting point, the activities of 1,3,5-trimethylbenzene molecules slow down, get close to each other, arrange regularly, and become a solid state.
    1,3,5-trimethylbenzene has a density of about 0.863g/cm ³, which is slightly lighter than water. When mixed with water, it can be clearly seen that it floats on the water surface, and the boundaries between the two are clear.
    In terms of solubility, 1,3,5-trimethylbenzene is insoluble in water, because its molecular structure is very different from that of water, and it is difficult to form an effective interaction. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc. In organic solvents, 1,3,5-trimethylbenzene molecules and solvent molecules are interspersed and uniformly mixed to form a uniform and stable system.
    In addition, 1,3,5-trimethylbenzene is volatile and can slowly evaporate from a liquid state to a gaseous state at room temperature, diffusing in the air. The relative density of its vapor is higher than that of air, about 4.1, so the vapor is easily deposited in the lower part and does not accumulate.
    What are the chemical properties of 1,3,5-trifluorobenzene?
    1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF, it is an organic compound. Its chemical properties are unique and worthy of investigation.
    This compound has a certain stability. Under normal temperature and pressure, it can maintain its own structure and not easily decompose. In its molecular structure, specific chemical bonds endow it with relatively stable properties. In case of extreme conditions such as high temperature and strong oxidants, the stability will also be affected.
    1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF has certain reactivity. It can react with a variety of reagents. For example, it can react with halogenating agents to introduce halogen atoms on the benzene ring. This reaction is based on the electron cloud distribution characteristics of the benzene ring. The electrophilic reagents of the halogenating agent can attack the benzene ring and cause electrophilic substitution reactions.
    It can also react with some metal-organic reagents to realize the modification and modification of its structure. This reaction mostly relies on the unique reactivity of metal-organic reagents to interact with specific functional groups or benzene rings of 1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF.
    In terms of solubility, 1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF soluble in some organic solvents, such as dichloromethane, chloroform, etc. This solubility characteristic is related to the polarity of its molecules. The overall polarity of the molecule is small, so it is more soluble in non-polar or weakly polar organic solvents.
    Furthermore, 1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF in some chemical reactions, it can be used as an intermediate. Due to the particularity of its structure, it can be converted into other more complex organic compounds with special functions through a series of reaction steps.
    In short, the chemical properties of 1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF are rich and diverse, and have important potential application value in the fields of organic synthesis, and are one of the important objects of organic chemistry research.
    What are the preparation methods of 1,3,5-trifluorobenzene?
    For 1% 2C3% 2C5-tribromobenzene, there is a way to make it. One method is to start with benzene, add bromine, and use iron or iron tribromide as a catalyst to carry out a bromination reaction. The reaction formula is as follows: benzene + 3Br < 3 > $\ xrightarrow [] {FeBr} $1% 2C3% 2C5-tribromobenzene + 3HBr. In this reaction, iron or iron tribromide can promote the interaction between bromine and benzene, so that bromine atoms enter the benzene ring, and most of them concentrate at the position of 1% 2C3% 2C5.
    Another method can first use acetophenone as a raw material and nitrate to obtain m-nitroacetophenone. Further reducing agents, such as iron and hydrochloric acid, make the nitro group into an amino group to obtain m-aminoacetophenone. After bromine and it, in an acidic environment, the amino group can be introduced into the benzene ring at the position of 1% 2C3% 2C5 to obtain 3% 2C5 -dibromo-4 -aminoacetophenone. At the end of the diazotization and deamination method, the amino group can also be removed to obtain 1% 2C3% 2C5 -tribromobenzene.
    Another method, starting with m-phenylenediamine, is diazotized to obtain m-phenylenediamine diazonium salt. Then cuprous bromide is used as the catalyst, interacts with potassium bromide, and the diazo group is the bromine atom, and 1% 2C3% 2C5-tribromobenzene is obtained. These various preparation methods have their own strengths and weaknesses. In practice, according to the ease of material, the difficulty of reaction, and the high or low yield, the appropriate one should be selected.
    What are the precautions for using 1,3,5-trifluorobenzene?
    1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E5%9C%A8%E4%BD%BF%E7%94%A8%E8%BF%87%E7%A8%8B%E4%B8%AD%E5%BD%93%E8%A7%86%E4%B8%8B%E4%B8%89%E4%B8%AA%E6%B3%A8%E6%84%8F%E4%BA%8B%E9%A1%B9:
    One, this medicine is toxic, although it is a good medicine, it should not be used with caution. When taking the medicine, you must follow the doctor's instructions and must not increase or decrease the dose by yourself to prevent the risk of poisoning. If there is discomfort during the medication, such as dizziness, nausea, vomiting, etc., stop the medicine immediately and seek medical treatment immediately.
    Both, when using 1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E5%9C%A8%E4%B8%8E other medicines, you must be cautious. Because of its special ingredients, or interaction with other medicines, it can cause changes in the efficacy of the medicine, or even cause adverse reactions. Therefore, when seeking medical treatment, when truthfully telling the doctor the medicine that the doctor is taking, so that the doctor can weigh the advantages and disadvantages and determine the method of safe medication.
    Three, storage methods are also important. It should be placed in a cool, dry place that is out of reach of children. If stored improperly, such as heat or moisture, it may cause the drug to deteriorate and its efficacy to be damaged. In this way, instead of treating the disease, it may delay the disease and even cause other diseases. In short, medication is related to life. In 1%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%9A%84%E4%BD%BF%E7%94%A8, it is necessary to check the doctor's advice carefully and pay attention to the above things to ensure the safety of medication and the success of treatment.