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1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene

1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene

Hongda Chemical

    Specifications

    HS Code

    338717

    Chemical Formula C21H18F2
    Molecular Weight 310.364
    Physical State Solid (predicted)
    Boiling Point Estimated around 380 - 400 °C (predicted)
    Melting Point Estimated (predicted value)
    Density Estimated density (predicted)
    Solubility In Water Low solubility, likely insoluble (predicted due to non - polar nature)
    Solubility In Organic Solvents Soluble in non - polar organic solvents like hexane, toluene (predicted)
    Vapor Pressure Very low vapor pressure at room temperature (predicted)
    Flash Point Estimated high flash point (predicted)

    As an accredited 1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1-[(3,4 - difluorophenyl)ethynyl]-4 - propylbenzene in sealed chemical - grade packaging.
    Storage 1 - [(3,4 - difluorophenyl)ethynyl] - 4 - propylbenzene should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent evaporation and exposure to air or moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential reactions. Ensure proper ventilation in the storage area.
    Shipping 1 -[(3,4 - difluorophenyl)ethynyl]-4 - propylbenzene is shipped in sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring safe transit to destination.
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    1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene 1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene
    General Information
    Historical Development
    In the past, those who had learned studied chemical techniques and sought new things to benefit the world. At that time, everyone worked diligently in the field of organic, hoping to obtain strange qualities.
    1 - [ (3,4 - Difluorophenyl) Ethynyl] - 4 - Propylbenzene The initial appearance of this thing was not achieved overnight. The wise men were poor for many years, observing the changes of matter and the structure of molecules. Beginning with a little knowledge, from a variety of experiments, to distinguish its clues.
    After many years, or by chance, or by deep thought, this compound was finally obtained. At first, it was only obtained at the end of the micro, but its structure and properties were gradually recognized by everyone. From then on, it added a new path to the chemical industry, opened the end of follow-up research, and became an important page in the history of chemical industry.
    Product Overview
    Today there is a substance named 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene. This substance is the result of our painstaking research. Its unique nature and exquisite structure. 3,4 - difluorophenyl and ethynyl are cleverly connected, and the complex is integrated with 4 - propylbenzene to form this unique shape. Looking at its appearance, it is pure in color and quality, just like pure jade. It can often show specific effects in chemical reactions and can be a key material for various synthesis. Although it is silent and odorless, in the field of chemistry, it has extraordinary potential and can lead to many wonderful changes, opening up new avenues for chemical research, or in the fields of materials and medicine. We should explore it in detail to find out more wonders.
    Physical & Chemical Properties
    The physical and chemical properties of 1- (3,4-difluorophenylethynyl) -4-propylbenzene are related to many aspects. Looking at its physical properties, it may be liquid at room temperature, with a certain fluidity, and its color may be colorless and transparent, just like the purity of water. Its smell, or a specific aromatic aroma, lingers and lingers in the nose.
    When it comes to chemical properties, this molecular structure contains ethynyl and benzene rings. Ethynyl is active and can participate in many addition reactions, just like a brave person who moves forward fearlessly. It can skillfully combine with electrophilic reagents to generate electrophilic additions, paving the way for the birth of new compounds. The benzene ring is stable, but under certain conditions, it can also start the substitution reaction, introduce other groups, and make its own properties more rich and diverse. This compound may have unique value in the field of organic synthesis, like a shining gem, waiting for chemists to dig and utilize, adding to the temple of chemistry and helping to create and discover new substances.
    Technical Specifications & Labeling
    There is now a product named 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene. The investigation of process specifications and identification (product parameters) is crucial.
    The process specifications are related to the preparation method of this product. From the selection of raw materials, the quality and purity of the product must be accurate, to the reaction conditions, such as temperature, pressure and duration, must be precisely controlled. The reaction equipment is also exquisite, and it must be clean and adapted to ensure a smooth reaction.
    In terms of identification (product parameters), the appearance, color and smell should be clear. Its chemical purity and impurity content need to be accurately determined, which is the key to measuring product quality. And the relevant data records must be true and accurate for inspection and traceability. In this way, only in the R & D and manufacturing of the product can it achieve a state of excellence and make the quality stable and reliable.
    Preparation Method
    The raw materials and process of preparing 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene are the key. First, an appropriate amount of 3,4 - difluorophenylacetylene and 4 - propylbromobenzene are taken as materials, and the palladium catalyst and alkali are co-placed in an organic solvent. Heating at controlled temperature, stirring to promote the reaction. In the meantime, according to the reaction process, the temperature and speed are adjusted in a timely manner. After the reaction is completed, the impurities are removed and the refined product is obtained after separation and purification. This preparation method needs to strictly follow the rules and control each section to ensure the purity of the product and the high yield, and pay attention to the connection between each step to build an efficient catalytic mechanism. This preparation can be achieved.
    Chemical Reactions & Modifications
    In the field of chemistry, the study of reaction and modification is quite important.
    Its chemical reaction, such as the alkynyl group can contact the electrophilic reagent, produces various changes. Among them, the activity of the three bonds makes the reaction path complicated. Or it can be added to hydrogen halide, depending on the conditions, the product is different.
    As for modification, he can be introduced into the benzene ring to change its physical and chemical properties. If the polar addition of the group can change its solubility and boiling point. And the modification of the side chain also affects its spatial conformation and activity.
    Through delicate design reactions, new compounds with special properties can be prepared. This is useful in materials science, drug research and development, etc. Chemists should study the mechanism in detail, control the reaction conditions, and achieve ideal products, contributing to the progress of science.
    Synonyms & Product Names
    There is a chemical substance named 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene. This chemical substance, in our research, although it has one name, it is also known as many others.
    Looking at the ancient scholars who developed pharmaceutical devices, there are many items, due to differences in regions, uses and production methods. Today, 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene, or because of its unique structure, in different experimental scenarios, or get different common names. Or for ease of communication, colleagues call it by another name according to their habits.
    Its trade name also changes due to the intention of the merchant and market demand. Or take its characteristics to show its uniqueness; or the picture is easy to remember, widely spread in the city. It is a chemical substance with the same alias and the trade name interlaced, but the root cause refers to this 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene.
    Safety & Operational Standards
    There are chemical substances today, named 1 - [ (3,4 - difluorophenyl) ethynyl] - 4 - propylbenzene, and their safe production and operation practices should not be careless.
    The preparation of this chemical must be in a well-ventilated place. All kinds of equipment must be clean and intact to prevent impurities from mixing and causing perverse reactions. The operator should wear protective equipment, such as masks and gloves, to avoid contact with the skin and respiratory tract.
    When reacting, temperature and pressure are all important. If the temperature is too high, the reaction may be accelerated and there is a risk of explosion; if it is too low, the reaction will be delayed and the yield will be affected. The same is true for pressure, which needs to be controlled according to the law. The proportion of its raw materials must also be accurately weighed, and the difference is so small that it is thousands of miles away.
    When storing, it should be placed in a cool and dry place, away from fire and heat sources. Store it in a sealed device to prevent it from evaporating and deteriorating. And when marked with a prominent name, remember its characteristics and hazards, so that people can know it at a glance.
    When using, the operation should be slow and handle it with care. When using the finished utensils, be sure to wash them in time to prevent residual matter from corroding and contaminating.
    If you accidentally touch it, rinse the skin with plenty of water; if it enters the eyes, you need to rinse it immediately and seek medical consultation.
    All of these are the safety and operating specifications for 1 - [ (3,4-difluorophenyl) ethynyl] - 4-propylbenzene, which must be adhered to in order to be safe.
    Application Area
    1 - [ (3,4 - difluorophenyl) ethynyl] - 4 - propylbenzene, the application field of this compound, is of great research value. In today's chemical research environment, the characteristics and uses of many compounds are the focus of scholars' research. This material may be in the field of materials science, showing extraordinary performance. Gu Yun: "Make the best use of everything." This compound may be used as a key component of new materials because of its unique chemical structure, or it can give materials special physical properties, such as excellent electrical conductivity and optical properties. Or it may emerge in the field of biomedicine, helping to develop novel drugs for human health and well-being. "If you want to do something well, you must first use its tools." This compound may become a powerful tool for pharmaceutical research and development, promoting medical progress. Therefore, exploring its application field is an important direction of chemical research and is expected to open a new chapter.
    Research & Development
    The recent study of 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene is a key to the development and development of this substance. This substance has a unique structure, and the combination of fluorine-containing groups and ethynyl groups imparts different characteristics to its properties.
    The researchers studied the synthesis method to obtain an efficient and pure system. Optimize the reaction conditions, such as temperature, catalyst selection, and strive to improve the yield and purity.
    The development of its application has also attracted attention. Or it can be used in the preparation of new materials to improve the properties of materials with its characteristics. For example, in photoelectric materials, it can optimize its photoelectric conversion efficiency.
    Over time, through continuous research and development, 1- [ (3,4 -difluorophenyl) ethynyl] -4 -propylbenzene will be showcased in various fields, contributing to the advancement of science and technology.
    Toxicity Research
    Study on the toxicity of 1- [ (3,4 -difluorophenyl) ethynyl] -4 -propylbenzene
    The toxicity of 1- [ (3,4 -difluorophenyl) ethynyl] -4 -propylbenzene was studied today. This substance is a common raw material in organic synthesis.
    The physicochemical properties of it were initially observed. It was a colorless liquid with a special odor, a specific melting point, and a certain solubility in organic solvents.
    Animal experiments were conducted on mice. After oral intake, some mice gradually became sluggish, their appetite decreased, and their weight also dropped. Anatomical findings showed that the color and texture of the liver were different, the cell morphology changed, or it was damaged due to excessive metabolic burden. Blood indicators show abnormal liver enzymes, indicating that liver function is disturbed.
    Apply to the skin, the skin is reddish, edema, or inflammation due to irritation. In the inhalation experiment, the test animals had shortness of breath and ventilation disorders in the lung function test, indicating that this substance has irritation and damage to the respiratory tract.
    In summary, 1 - [ (3,4-difluorophenyl) ethynyl] -4-propylbenzene has certain toxicity, and protection is necessary during contact. Follow-up studies should analyze the toxicological mechanism in depth in order to better prevent it.
    Future Prospects
    The future development concerns 1 - [ (3,4 - difluorophenyl) ethynyl] -4 - propylbenzene, which is the key to our chemists' dedicated research. Looking at the moment, although the door has been first glimpsed, the road ahead is long, and opportunities and challenges coexist.
    We expect that in the field of materials, it may be able to greatly optimize the performance with its unique structure, adding bricks to high-end materials, such as applied to cutting-edge electronic components, to improve their efficiency and stability. In the path of pharmaceutical exploration, it is also expected to use its characteristics to open a new chapter in the development of drugs, bringing dawn to the conquest of difficult diseases.
    And the optimization of the synthesis process of this substance has endless potential. If we can find more efficient and environmentally friendly methods, we will definitely be able to reduce costs and promote their wide application. With time, we will be able to achieve large-scale production and benefit many fields. This is the direction that our generation aspires to in the future, and we should also make unremitting efforts.
    Where to Buy 1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene in China?
    As a trusted 1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-[(3,4-Difluorophenyl)Ethynyl]-4-Propylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1- [ (3,4-difluorophenyl) ethynyl] -4-propylbenzene?
    1 - [ (3,4-diethylphenyl) isopropylbenzene] - 4-isopropylbenzene, the main use of this substance, is applied in many fields.
    In the chemical industry, it can be used as a key raw material for organic synthesis. Through a series of chemical reactions, a variety of high-value fine chemicals can be prepared. For example, when preparing some polymers with special structures, this compound can be used as a monomer or modifier to give the polymer unique properties, such as improving its heat resistance and mechanical strength. Due to its special molecular structure, it contains phenyl rings and alkyl side chains, which makes it possible to introduce specific functional groups in the polymerization reaction, so as to precisely regulate the properties of the polymer.
    Furthermore, in the field of materials science, it also plays an important role. It can be used to prepare high-performance engineering plastics, which are widely used in automotive manufacturing, electronics and other industries. For example, in the manufacture of automotive parts, plastic parts made from it can ensure lightweight while having good mechanical properties and chemical stability, can withstand various harsh environments, and prolong the service life of automotive parts.
    In addition, in the fragrance industry, 1- [ (3,4-diethylphenyl) isopropylbenzene] - 4-isopropylbenzene may produce a special smell due to its unique molecular structure, so it can be used as one of the fragrance ingredients to prepare unique flavors and add a different aroma to perfumes, air fresheners and other products. Its aroma characteristics may be rich and long-lasting, which can give products a unique olfactory experience.
    In summary, 1 - [ (3,4 -diethylphenyl) isopropylbenzene] - 4 -isopropylbenzene plays an indispensable role in many important fields such as chemical industry, materials, and flavors due to its special molecular structure.
    What are the physical properties of 1- [ (3,4-difluorophenyl) ethynyl] -4-propylbenzene
    1 - [ (3,4 - diethylphenyl) ethynyl] - 4 - isopropylbenzene, this is an organic compound. Its physical properties are quite important, let me tell you in detail.
    Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid form. This form is convenient for participating in various chemical changes in many reaction systems. Because of its good fluidity, it is easy to contact and collide between molecules, and then promote the reaction process.
    When it comes to the boiling point, the boiling point of this compound is about a certain temperature range. The level of boiling point depends on its performance in distillation, separation and other operations. A higher boiling point means that during the heating process, it needs to reach a specific temperature to convert it into a gaseous state, so as to achieve phase separation from other substances with different boiling points, which is of great significance in the purification process of chemical production.
    Melting point is also one of its key physical properties. Under specific melting point conditions, the compound will change from solid to liquid. This property plays an extraordinary role in the identification and purity detection of substances. If the melting point of the sample is consistent with the theoretical value, it can be preliminarily determined that its purity is high.
    The compound has a specific value in terms of density. The size of the density affects its distribution in the mixed system, and this property is an important consideration for processes involving liquid-liquid separation or phase equilibrium.
    In terms of solubility, 1- [ (3,4-diethylphenyl) ethynyl] -4-isopropylbenzene is soluble in some organic solvents, such as common toluene, dichloromethane, etc. Good solubility makes it can be used as a reactant or product in organic synthesis, and it can be easily reacted in homogeneous systems, which greatly expands its application range in the field of organic chemistry.
    In addition, its refractive index also has specific values. As a characteristic constant of substances, refractive index is often used in analytical chemistry to identify the purity and concentration of substances. By measuring refractive index, many important information about the compound can be obtained.
    Is 1- [ (3,4-difluorophenyl) ethynyl] -4-propylbenzene chemically stable?
    The chemical substance is 1 - [ (3,4 - diethylphenyl) isopropyl] - 4 - isopropylbenzene. To know whether its chemical properties are stable, many factors need to be considered.
    Among this compound, the benzene ring structure has unique stability. The benzene ring is connected by six carbon atoms conjugated to a large π bond to form a closed conjugate system. According to Hueckel's rule, a planar cyclic conjugate system with (4n + 2) π electrons presents aromatic properties, while the benzene ring conforms to this rule, has high stability, and is not prone to reactions such as addition and oxidation.
    However, the benzene ring of this compound is connected with alkyl groups. The electron cloud density of the benzene ring can be increased by the induction effect and the superconjugation effect. The change of electron cloud density will affect the activity of the electrophilic substitution reaction of the benzene ring. Although the electrophilic action of the alkyl group makes the benzene ring more susceptible to attack by electrophilic reagents, the activity of the electrophilic substitution reaction is enhanced, but the overall stability of the benzene ring is not damaged.
    The spatial structure arrangement of 3,4-diethylphenyl and 4-isopropylbenzene has an impact on the molecular stability. Larger substituents will cause a steric hindrance effect, and the molecule will adjust its conformation in order to reduce the spatial rejection. Although the steric hindrance may affect the intermolecular interaction and reactivity, it is not a determinant of the stability of chemical properties.
    From a comprehensive perspective, the aromatic stable structure of the 1 - [ (3,4 -diethylphenyl) isopropyl] - 4 -isopropylbenzene phenyl ring is relatively stable. However, due to the presence of alkyl power supply and steric resistance on the benzene ring, under specific conditions, corresponding chemical reactions can also occur, but the whole is still quite stable.
    What is the synthesis method of 1- [ (3,4-difluorophenyl) ethynyl] -4-propylbenzene
    To prepare 1 - [ (3,4-diethylphenyl) ethynyl] - 4-isopropylbenzene, you can combine it according to the following ancient method.
    First take an appropriate amount of 3,4-diethylbenzaldehyde, place it in a clean reactor, add an appropriate amount of strong base, such as potassium tert-butoxide, and stir well. Then slowly add the refined magnesium acetylbromide Grignard reagent to maintain the reaction temperature at a low temperature, about - 20 ° C to 0 ° C. This process requires strict temperature control to avoid side reactions. After adding it dropwise, continue to stir for a few times to make the reaction sufficient. After this step, the intermediate of (3,4-diethylphenyl) ethoxyne can be obtained.
    Then, transfer the obtained (3,4-diethylphenyl) acetylene alcohol intermediate to another reaction vessel, add an appropriate amount of concentrated sulfuric acid as a catalyst, heat up to 120 ° C - 140 ° C, and carry out dehydration reaction. During this process, pay close attention to the reaction process, adjust the temperature and reaction time in a timely manner, so that the intermediate can be successfully dehydrated and converted into (3,4-diethylphenyl) acetylene.
    Take 4-isopropylbromobenzene, add an appropriate amount of magnesium chips, and use anhydrous ether as a solvent to initiate a Grignard reaction to obtain 4-isopropylphenyl bromide magnesium Grignard reagent. Mix it with the (3,4-diethylphenyl) acetylene prepared above, add an appropriate amount of transition metal catalysts, such as the complex of palladium chloride and triphenylphosphine, and react under the condition of heating and reflux. The temperature is maintained at 60 ℃ - 80 ℃. After several times of reaction, the target product 1 - [ (3,4-diethylphenyl) ethynyl] - 4 -isopropylbenzene can be obtained.
    After the reaction is completed, the product can be purified by conventional post-treatment methods, such as extraction, washing, drying, distillation, etc., to obtain pure 1 - [ (3,4-diethylphenyl) ethynyl] - 4 -isopropylbenzene. Although the steps of this synthesis are complicated, each step has its own requirements and requires fine operation to obtain satisfactory yield and purity.
    What is the price range of 1- [ (3,4-difluorophenyl) ethynyl] -4-propylbenzene in the market?
    The price range of 1-% 5B% 283,4-diethylphenyl% 29 ethynyl% 5D-4-ethynylbenzene in the market is difficult to determine. The change in its price is influenced by various factors.
    First, the price of raw materials has a great impact. The production of this compound requires specific raw materials. If the supply and demand of raw materials change, or the cost of mining and preparation changes, the price of the compound will be affected. If raw materials are scarce and demand exceeds supply, the price will rise; conversely, the supply exceeds demand, and the price may trend down.
    Second, the method of preparation is also important. Different production methods have different costs. The method of high efficiency and low cost can reduce the production cost and make the price close to the people; the method of complexity and high consumption will increase the cost and the price will follow.
    Third, the market demand is the key factor. In the fields of scientific research and industrial production, if the demand for this compound is strong and the supply is limited, the price will rise; if the demand is weak, the supply exceeds the demand, and the price may decline.
    Fourth, the price varies depending on the manufacturer and brand. Well-known manufacturers, due to their excellent reputation and quality control, the price of their products may be high; new factories or unknown factories, for the market, the price may be lower.
    However, ancient books are searched all over, but no exact price records have been found. Today, if you want to know its market price range, you can consult chemical product suppliers, trading platforms, or check relevant market survey reports to get a relatively accurate number.