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1,2-Dinitro-4-Fluorobenzene

1,2-Dinitro-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

624418

Chemical Formula C6H3F(NO2)2
Molar Mass 186.09 g/mol
Appearance Yellow - orange solid
Melting Point 21 - 23 °C
Boiling Point 294 - 296 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Density 1.57 g/cm³
Vapor Pressure Low
Flash Point 145 °C
Hazardous Nature Toxic, irritant

As an accredited 1,2-Dinitro-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2 - dinitro - 4 - fluorobenzene packaged in a sealed, corrosion - resistant container.
Storage 1,2 - dinitro - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat, sparks, and open flames as it is flammable. Store it in a tightly sealed container to prevent vapor leakage. Separate it from oxidizing agents, reducing agents, and bases to avoid chemical reactions. Store at a temperature below 30°C.
Shipping 1,2 - dinitro - 4 - fluorobenzene is a hazardous chemical. Shipping requires proper packaging in accordance with regulations. It must be transported by approved carriers, with appropriate labeling indicating its dangerous nature for safe handling.
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1,2-Dinitro-4-Fluorobenzene 1,2-Dinitro-4-Fluorobenzene
General Information
Historical Development
1,2-Dinitro-4-fluorobenzene is also a chemical substance. Its origin can be traced back to the past. At the beginning, various sages studied diligently in the field of chemistry, wanting to explore the novelty of matter, and this compound gradually appeared in the world.
At that time, everyone was amazed by its unique chemical properties. After many experiments, I learned that it can play a wonderful role with other things, emerging in the field of organic synthesis.
Over the years, researchers have been unremitting, and their understanding of 1,2-dinitro-4-fluorobenzene has deepened. It has unique uses in medicine, materials, and other aspects, adding a touch of color to the progress of chemistry. It has gradually drifted away from the path of science, and its brilliance has become more and more apparent.
Product Overview
1,2-Dinitro-4-fluorobenzene is an important substance in chemical research. It is an aromatic halide with unique chemical properties. In this compound, the structure of fluorine atoms and dinitro groups makes its activity extraordinary.
In the field of organic synthesis, 1,2-dinitro-4-fluorobenzene is often used as a key intermediate. Because of its active fluorine atoms, it is easy to be replaced by nucleophiles, which can introduce various functional groups into molecules and expand the structure and properties of compounds.
Furthermore, it has applications in biochemical research. It can react with specific groups of biological macromolecules such as proteins and nucleic acids, which helps to explore the structure and function of biomolecules.
It should be noted that 1,2-dinitro-4-fluorobenzene is toxic and dangerous. When operating, strict safety procedures must be followed to prevent harm to people and the environment.
Physical & Chemical Properties
1,2-Dinitro-4-fluorobenzene is an important substance for chemical research. Its physical and chemical properties are unique and related to many chemical processes. Looking at its shape, it often takes a specific state, or is crystalline, or is a different appearance. Its color may appear, which can help researchers to distinguish it.
Regarding its physical properties, the melting point is a key characterization. Under a specific temperature, this substance undergoes a phase transition, from solid to liquid, or from liquid to gas. This temperature range reflects the strength of its intermolecular forces. Furthermore, solubility is also a key point. In different solvents, its solubility varies, either easily soluble or slightly soluble, which is closely related to the polar solvent and molecular structure.
As for chemical properties, 1,2-dinitro-4-fluorobenzene is reactive. The presence of nitro groups changes the electron cloud density of the benzene ring, making it prone to nucleophilic substitution. Fluorine atoms are also active and can interact with a variety of nucleophilic reagents to form new compounds, which are widely used in the field of organic synthesis.
Technical Specifications & Labeling
For 1,2-dinitro-4-fluorobenzene, the process specifications and identification (product parameters) are the key. Looking at this substance, the preparation process needs to be precise. At the beginning of the reaction, the proportion of all raw materials must be appropriate, such as [specific raw material 1] and [specific raw material 2], according to a specific ratio, at a suitable temperature and duration, gradually react. The control of temperature is related to success or failure, and must be between [specific temperature range], and there should be no slight deviation.
As for the identification, it should be detailed and clear. The name of the product and the chemical formula "1,2 - Dinitro-4 - Fluorobenzene" must be clearly marked. Its physical properties, such as color, odor, melting point, boiling point and other parameters, should not be omitted. The identification of chemical properties, such as stability, reactivity, etc., must be clearly stated so that the user can handle it carefully, avoid danger and ensure the smooth operation of the experiment and production.
Preparation Method
The preparation method of 1,2-dinitro-4-fluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical. When fluorobenzene is used as the starting material, this is the basis of the reaction.
In terms of production process, fluorobenzene is first placed in a specific reactor, and the mixed acid is slowly added dropwise under a low temperature environment. The mixed acid is prepared by the delicate ratio of concentrated nitric acid and concentrated sulfuric acid, just like the secret recipe of ancient processing. The drip addition process must be careful, just like the ancient alchemy to control the temperature and drip acceleration, to prevent unexpected changes.
The reaction steps are also exquisite. After the dropwise addition is completed, heat up to a certain range and continue to stir to make it fully react. This stage is like a slow simmer, and you need to wait patiently to make the reaction reach the best state.
In the catalytic mechanism, concentrated sulfuric acid plays an important role in this reaction, just like a wise man, speeding up the reaction process and improving the product generation efficiency. After this series of operations, 1,2-dinitro-4-fluorobenzene can be obtained. This preparation method contains many details and needs to be followed carefully to achieve a good product.
Chemical Reactions & Modifications
1,2-Dinitro-4-fluorobenzene is also an organic compound. Its chemical reaction and modification are the gist of our research.
Looking at its chemical reaction, 1,2-dinitro-4-fluorobenzene is active, and fluorine atoms are easily replaced by nucleophiles. Because of its strong electrosorption effect, the electron cloud density of the benzene ring decreases, and the electron cloud density around the fluorine atom also decreases, causing its activity to increase. If it encounters an amine nucleophile, the fluorine atom is quickly replaced by an amine group to form a new nitrogen-containing compound.
As for modification, other groups can be introduced into the benzene ring to change its properties. After modification, it can increase its stability, or change its solubility, or change its reactivity. This is useful in the creation of new materials and drug research and development fields.
We should study its chemical and modification in depth, seeking to expand the way and create more benefits in the chemical, pharmaceutical and other industries.
Synonyms & Product Names
1,2-Dinitro-4-fluorobenzene is an important chemical compound in chemical research. There are many synonyms, or 4-fluoro-1,2-dinitrobenzene, which all refer to the same thing. As for the trade name, in the chemical market, there are also different names.
This substance is often a key reagent in the field of chemical experiments. Because of its unique chemical structure, it plays an important role in organic synthesis and other aspects. When chemists explore various reaction mechanisms, 1,2-dinitro-4-fluorobenzene is often an important medium to help them understand the mysteries of chemical changes. Therefore, knowing its synonyms and trade names is an important thing for chemical researchers, so that they can use this material more accurately in academic exchanges and experimental operations, and promote the process of chemical research.
Safety & Operational Standards
1,2-Dinitro-4-fluorobenzene is also a chemical substance. Its safe production and operation specifications, we should be cautious.
This substance is dangerous and toxic. When operating, be sure to wear appropriate protective equipment, such as gas masks, protective gloves, protective clothing, etc., to prevent toxic gases from entering the body and hurting the skin.
The place where it is operated should be well ventilated, and effective ventilation devices should be installed to make harmful gases disperse quickly and not gather indoors. Furthermore, the temperature and humidity of the operating environment must also be controlled to avoid the risk of accidents due to temperature and humidity discomfort. When
is stored, it should be placed in a cool, dry and ventilated place, away from fire and heat sources, and stored separately from oxidizers and alkalis, etc., and should not be mixed to prevent interaction and cause disasters.
When taking it, it must be taken according to the precise quantity and specifications, and it must not be exceeded, nor should it be done hastily. After operation, the remnants should not be discarded at will. They need to follow specific treatment procedures and properly dispose of them, so as not to pollute the environment and cause harm to all parties.
During transportation, it is also necessary to strictly abide by the transportation rules to ensure that the packaging is intact and prevent its leakage. The escort, when familiar with the characteristics of this object and emergency methods, can deal with emergencies calmly and ensure the safety of the road.
In short, the safety and operating standards of 1,2-dinitro-4-fluorobenzene are related to human life and the environment, and we chemical researchers must abide by them without slack.
Application Area
1,2-Dinitro-4-fluorobenzene is also a chemical product. Its application field is quite extensive. In the field of pharmaceutical research and development, it is often used as a key intermediate to help the creation of new drugs, to treat various diseases and help the world's diseases. In the field of dye chemical industry, it can be used as a color-forming raw material, giving dyes unique color and properties, and increasing its application effect. It is also in the process of material science, or as a modification aid, so that materials have specific properties and are suitable for different uses. Although it is not impressive in appearance, it plays an important role in various application fields and is indispensable for chemical research and industrial production.
Research & Development
In the field of chemical industry, new products are produced, and 1,2-dinitro-4-fluorobenzene is also something we have dedicated ourselves to studying. This material is unique, related to various reaction mechanisms, and is of great value to explore.
My colleagues and I studied day and night, hoping to understand its mysteries. In the laboratory, various instruments were listed, and repeated tests were conducted to observe its changes. At the beginning, the results were not obvious, but we were not discouraged.
After long-term research, we gradually gained something. Knowing that it can trigger unique reactions under specific conditions is expected to be applied to the development of new pharmaceuticals. With time, careful carving may be able to add bricks and mortar to the field of medicine and promote the development of the industry, which is also the hope of our scientific researchers. Although the road ahead is long, we will uphold our original intention and unswervingly make unremitting efforts for its development.
Toxicity Research
In the case of 1,2-dinitro-4-fluorobenzene, the study of toxicology is very important. This substance is strong and highly toxic. In past experiments, we have carefully observed its signs of toxicity.
Its entry into the body, or through the skin, or through breathing, can cause harm. Taste the subject, touch it, the skin will produce erythema, blister, and pain. If you inhale its breath, the lungs will be invaded, and the symptoms of asthma and shortness of breath will occur frequently. And in the body, it can mess with the ability of the viscera and damage the organs of the liver and kidneys.
Therefore, studying its toxicity and investigating the mechanism of its harm can be used to find ways for protection and treatment. The researchers in the future will explore it more deeply, clarify the source of its poison, formulate good policies to control its harm, and ensure that everyone is born in a safe place.
Future Prospects
1,2-Dinitro-4-fluorobenzene is also a chemical substance. In today's world, its research is well-developed, but it has not yet been developed, especially in the future.
As we know, it has not been developed or can be developed in the field. With its characteristics, it may be helpful to the treatment of new diseases and general diseases. For example, some diseases may be able to solve the pain of patients by virtue of their reflexivity and the development of special effects.
And in the field of materials, it also has power. Or it can be developed through special methods to make it an essential element of a new type of material, and to give the material its unique properties, such as better quality and performance, etc., to meet different needs.
Therefore, the development of 1,2-dinitro-4-fluorobenzene has not yet been completed. Our scientific researchers have diligently explored and hope to expand its prospects.
Where to Buy 1,2-Dinitro-4-Fluorobenzene in China?
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Frequently Asked Questions

As a leading 1,2-Dinitro-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-dinitro-4-fluorobenzene?
1% 2C2-diamino-4-chlorobenzene is an important raw material for organic synthesis. It has key uses in many fields.
First, in the dye industry, it can be called the cornerstone. With this as the starting material, through a series of delicate chemical reactions, colorful and fastness dyes can be prepared. For example, the common azo dye, 1% 2C2-diamino-4-chlorobenzene, in the synthesis process, is coupled with specific diazo compounds to give the dye its unique color and properties, and is widely used in fabric printing and dyeing, making the fabric show a variety of colors.
Second, in the field of medicine, it is also indispensable. On this basis, through ingenious structural modification and synthesis, a variety of drugs with specific pharmacological activities can be developed. The synthesis of some antibacterial drugs uses 1% 2C2-diamino-4-chlorobenzene as the key intermediate, and its structural characteristics help the drug to exert antibacterial effect and escort human health.
Third, it plays an important role in pesticides. It can be used as an important raw material for synthetic pesticides to synthesize pesticide products with high insecticidal, bactericidal or herbicidal properties. The creation of some new insecticides, 1% 2C2-diamino-4-chlorobenzene, provides strong support for pest control in agricultural production and ensures the harvest of crops.
Fourth, it also has a place in the field of rubber additives. Some additives synthesized from this raw material can effectively improve the processing properties and physical properties of rubber, such as increasing the vulcanization speed of rubber, enhancing the wear resistance of rubber, etc., so that rubber products can play a better role in industry, transportation and other fields.
In short, 1% 2C2-diamino-4-chlorobenzene, with its unique chemical structure, plays a pivotal role in dyes, medicine, pesticides, rubber additives and other industries, promoting the development and progress of related industries.
What are the physical properties of 1,2-dinitro-4-fluorobenzene?
1% 2C2-diamino-4-nitrobenzene is an organic compound. Its physical properties are as follows:
This substance is mostly a yellow crystalline solid at room temperature and is quite stable. The melting point is between 174 ° C and 176 ° C. Due to factors such as intermolecular forces, the lattice structure is destroyed at this temperature and changes from solid to liquid. The boiling point is quite high, about 359.8 ° C, indicating that higher energy is required to vaporize it, reflecting the strong intermolecular forces.
Its density is about 1.47g/cm ³, which is larger than that of water. If placed in water, it will sink to the bottom. It is insoluble in water because it is an organic compound with relatively small molecular polarity, and it is difficult to form effective interactions with water molecules. However, it is soluble in organic solvents such as ethanol, ether, acetone, etc., and follows the principle of "similar phase dissolution". These organic solvents are similar to 1% 2C2-diamino-4-nitrobenzene molecules and can be well miscible.
In appearance, the morphology of yellow crystals gives it unique optical properties, which cause it to appear yellow due to the absorption and reflection of specific wavelengths of light. In addition, the substance has a certain odor, because its volatility is weak, the odor is relatively weak. The physical properties of
1% 2C2-diamino-4-nitrobenzene are of great significance in the fields of organic synthesis and dye preparation. Understanding these properties is helpful to grasp its reaction characteristics and application scenarios.
What are the chemical properties of 1,2-dinitro-4-fluorobenzene?
1% 2C2-diamino-4-bromobenzene has different properties, which is related to chemistry and is quite important.
This substance has significant chemical properties. In terms of its activity, the presence of bromine atoms and amino groups makes the compound highly active. Amino is an electron-rich group, which can influence the distribution of electron clouds in the benzene ring by means of conjugation and induction effects. It can increase the density of electron clouds in the adjacent and para-sites of the benzene ring, resulting in a significant increase in the activity of electrophilic substitution reactions at this position. Although bromine atoms are halogen elements and have electron-absorbing induction effects, they also have an effect on electrophilic substitution reactions because the lone pair electrons can be conjugated with the benzene ring to stabilize the positive ion intermediate of the benzene ring to a certain extent.
When it comes to reactivity, the substance can involve a variety of reactions. Its amino group can form a salt with an acid, and can also participate in the acylation reaction, and react with an acid chloride or an acid anhydride to form an amide. Bromine atoms can be replaced by other groups through nucleophilic substitution reaction under suitable conditions. Such as reacting with nucleophiles containing hydroxyl groups and amino groups to generate new compounds.
Furthermore, its physical properties also have characteristics. In view of the existence of amino groups, the compound may have a certain water solubility, because amino groups can form hydrogen bonds with water molecules. However, bromine atoms are hydrophobic, or their water solubility is limited. And hydrogen bonds can be formed between molecules with amino groups, which affects their melting point, boiling point and other physical parameters.
This 1% 2C2-diamino-4-bromobenzene, with its unique chemical properties, has important uses in organic synthesis, drug research and development, and can provide key raw materials and intermediates for the preparation of complex organic compounds and innovative drugs.
What are the precautions for using 1,2-dinitro-4-fluorobenzene?
1% 2C2-diamino-4-bromobenzene is a commonly used chemical substance. During use, pay attention to the following things:
First, safety protection is essential. This substance is toxic and irritating to a certain extent, touching the human body or causing skin allergies, eye discomfort and even more serious health damage. Therefore, when using, be sure to wear appropriate protective equipment, such as gloves, protective glasses and masks, to prevent direct contact. In case of inadvertent contact, rinse with plenty of water immediately and seek medical treatment according to specific conditions.
Second, proper storage is crucial. It should be stored in a dry, cool and well-ventilated place, away from fire sources and oxidants. Due to its active chemical nature, improper storage or deterioration can even cause dangerous reactions. At the same time, it is necessary to ensure that the storage container is well sealed to prevent volatilization and leakage.
Third, the operating specifications cannot be ignored. During use, it is necessary to strictly follow the established experimental procedures and operating guidelines. During the chemical reaction, the reaction conditions, such as temperature, concentration and reaction time, are precisely controlled to ensure the smooth progress of the reaction and avoid accidents. After use, the relevant instruments and places are thoroughly cleaned to prevent pollution caused by residual substances.
Fourth, environmental impact also needs to be paid attention to. If this substance enters the environment, it may have an impact on the ecosystem. Therefore, during the use and disposal process, environmental protection requirements should be followed, waste should be reasonably disposed of, and waste should not be discharged at will, so as not to pollute soil, water sources and other environmental factors.
What is the preparation method of 1,2-dinitro-4-fluorobenzene?
To prepare the drug of 1,2-diamino-4-bromonaphthalene, the method is as follows:
First take an appropriate amount of naphthalene and place it in a reactor. Using bromine as a brominating agent, under appropriate catalyst and reaction conditions, the bromination reaction is carried out. The key to this step is to precisely control the amount of bromine, reaction temperature and time, so that the bromine atom just replaces the hydrogen atom at a specific position on the naphthalene ring to obtain 4-bromonaphthalene.
Then, transfer 4-bromonaphthalene into another reaction device, use an appropriate amination agent, such as liquid ammonia, and add a suitable catalyst. Under suitable temperature, pressure and other conditions, the bromine atom is replaced by an amino group. In this process, the regulation of reaction conditions is extremely important. If the temperature is too high or too low, and the pressure is improper, the reaction yield may be reduced or by-products may be formed.
After the reaction is completed, the steps of separation and purification are required. First, the reaction product is extracted with a suitable solvent to preliminarily separate the target product from the impurities. Then it is further purified by distillation, recrystallization, etc., to obtain high-purity 1,2-diamino-4-bromonaphthalene.
When operating, it is necessary to strictly abide by safety procedures, because the reagents used are often toxic, corrosive or flammable and explosive. Detailed monitoring and recording of the reaction process, and timely adjustment of the reaction parameters to ensure the smooth preparation process and qualified products.