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1,2-Dimethyl-4-Fluorobenzene

1,2-Dimethyl-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

258561

Chemical Formula C8H9F
Molecular Weight 124.155 g/mol
Appearance Liquid (usually)
Odor Typical aromatic odor
Density Around 0.98 g/cm³ (estimated)
Boiling Point Approx. 150 - 155 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Around 40 - 50 °C (estimated)
Vapor Pressure Low at room temperature
Refractive Index Approx. 1.48 - 1.50 (estimated)

As an accredited 1,2-Dimethyl-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2 - dimethyl - 4 - fluorobenzene packaged in 500 - mL glass bottles, 10 bottles per carton.
Storage 1,2 - dimethyl - 4 - fluorobenzene should be stored in a cool, well - ventilated area, away from sources of ignition. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Given its flammable nature, ensure storage facilities have proper fire - fighting equipment and comply with safety regulations.
Shipping 1,2 - dimethyl - 4 - fluorobenzene is shipped in tightly sealed, specialized containers. It adheres to strict chemical transportation regulations, ensuring safety during transit to prevent any leakage or exposure risks.
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1,2-Dimethyl-4-Fluorobenzene 1,2-Dimethyl-4-Fluorobenzene
General Information
Historical Development
1,2-Dimethyl-4-fluorobenzene is also an organic compound. At the beginning, chemists used exquisite methods to explore the properties of various things, and in the midst of complex experiments, they began to obtain this quality. In the past, the chemical sages studied the physical properties, analyzed its structure, and clarified its composition, which made this compound stand out.
At the beginning, the preparation method was still simple, but the quantity was quite small, and the pure one was difficult to find. After several generations of chemists studied and improved the process, the preparation method became more and more refined, and the yield also increased. Today, 1,2-dimethyl-4-fluorobenzene is widely used in chemical, pharmaceutical, and other fields, contributing to the development of many industries. It is a shining pearl in the development of chemistry, witnessing the process of chemical technology from simple to complex and increasingly perfect.
Product Overview
1,2-Dimethyl-4-fluorobenzene is an organic compound. It may be a colorless liquid with a special odor. This substance is formed by the combination of carbon, hydrogen and fluorine elements. In the molecular structure, on the benzene ring, the two-position and one-position are connected to methyl groups, and the four-position is connected to fluorine atoms.
In the field of organic synthesis, 1,2-dimethyl-4-fluorobenzene is often used as a key intermediate. Due to the characteristics of benzene ring and substituents, a variety of chemical reactions can be derived. Or involve nucleophilic substitution, electrophilic substitution and other reaction types, in order to expand its application in medicine, pesticides, materials and other industries.
Its physical properties, such as its boiling point, melting point, density, etc., are specific due to the interaction between atoms in the molecule. Chemically, the stability of the benzene ring and the activity of the substituent interact, resulting in its unique reactivity, which has attracted much attention in the process of chemical research and development.
Physical & Chemical Properties
1,2-Dimethyl-4-fluorobenzene is also an organic compound. Its physical and chemical properties can be studied.
Looking at its physical properties, under normal temperature, it is a colorless liquid with a special odor. Its boiling point and melting point are all characteristics. The boiling point is about a specific temperature, so that it changes from liquid to gas; the melting point determines the change of its solid-liquid. Density is also an important feature, related to the ratio of its mass to volume.
As for the chemical properties, the structure of the benzene ring gives it a unique reactivity. The introduction of fluorine atoms changes its chemical behavior. It can react with a variety of reagents, and electrophilic substitution is common. Due to the strong electronegativity of fluorine, it affects the electron cloud distribution of benzene ring, causing the reaction check point to be different from ordinary benzene derivatives. This compound may have important uses in the field of organic synthesis. With its unique physical and chemical properties, it can be used as an intermediate and is the basis for the creation of new compounds.
Technical Specifications & Labeling
Technical Specifications and Labeling of 1,2-Dimethyl-4-Fluorobenzene (Product Parameters)
For Fu 1,2-Dimethyl-4-Fluorobenzene, its technical specifications are fine selection of the first heavy raw materials. The materials used must be accurate with high purity, and the impurities must be small. In the synthesis method, follow a strict order. Temperature control and speed regulation are all important. The temperature should be stable in a certain area, and the speed should be appropriate to prevent side reactions.
In terms of its logo, on the packaging, when the name of the declaration "1,2-Dimethyl-4-Fluorobenzene" is attached with a clear structural formula to show its molecular structure. And marked with the number of purity, such as more than 99%, the water content must be in a small amount. Reinjection is a sign of danger, indicating that it has the risk of burning and poisoning, so that the operator can be warned. Commodity parameters are also listed in detail, such as molecular weight, boiling point, melting point of the genus, for reference.
Preparation Method
The process of making 1,2-dimethyl-4-fluorobenzene involves raw materials and production processes, reaction steps and catalytic mechanisms. The selection of raw materials is crucial, and pure and suitable reactants need to be selected.
For the production process, the specific aromatic hydrocarbons and fluorine-containing reagents are mixed in a precise ratio and put into a special reactor. Control the appropriate temperature and pressure to make the reaction step by step. In the initial stage, the temperature should be raised slowly, until the reaction is stable, and then fine-tuned to the optimal reaction interval.
The reaction steps are rigorous and orderly. First, the fluorine atom precisely replaces the hydrogen atom at a specific position in the benzene ring through a substitution reaction; followed by a methylation step, dimethyl is introduced. Each step requires strict monitoring of the reaction process. Advanced detection methods, such as gas chromatography and mass spectrometry, can provide insight into the degree of reaction and product purity. The
catalytic mechanism relies on high-efficiency catalysts to reduce the activation energy of the reaction and accelerate the reaction rate. The selected catalyst has high selectivity to ensure the formation of the target product. During the whole reaction, pay close attention to the activity of the catalyst, and adjust the dosage and reaction conditions in a timely manner to achieve the optimal production efficiency and obtain high-purity 1,2-dimethyl-4-fluorobenzene products.
Chemical Reactions & Modifications
The chemical reactions and modifications of 1,2-dimethyl-4-fluorobenzene are worth exploring in recent years. The change of chemistry is related to the clutch and easier structure of molecules. The characteristics of 1,2-dimethyl-4-fluorobenzene in various reactions are apparent in the breaking and formation of bonds.
In past experiments, it was often used in conventional methods to observe its interaction with other substances, but the effect was not satisfactory. If you want to improve, you must think of new ways. In its structure, the position of fluorine atoms and dimethyl groups affects the reactivity. To change its properties, you can start by adjusting the reaction conditions, such as temperature and pressure, or adding suitable catalysts.
The rise and fall of temperature can promote the rapid movement of molecules and make the reaction rate different. The change of pressure depends on the frequency of molecular collisions. The catalyst can reduce the energy barrier of the reaction and lead the reaction to a favorable direction. In this way, the chemical reaction and modification of 1,2-dimethyl-4-fluorobenzene may have a new look, which is a different path for chemical researchers.
Synonyms & Product Names
1,2-Dimethyl-4-fluorobenzene is a substance in the field of chemistry. Its synonymous name is also the focus of research.
Considering this substance, its synonymous name is also called by other names in the industry. If it is recorded in ancient books and discussed by colleagues, it may be called by another name, but it all refers to this 1,2-dimethyl-4-fluorobenzene. As for the trade name, when it is in circulation in the market, there is also a specific name for the purpose of distinction and identification.
The study of the synonymous name and trade name of this substance is meaningful in both academic circles and industries. Scholars can use this to clarify the term rheology, and the industry can apply it accurately to avoid confusion. Therefore, it is necessary to study its synonyms and trade names in detail to promote the smooth research and application of this chemical substance.
Safety & Operational Standards
Specifications for safety and operation of 1,2-dimethyl-4-fluorobenzene
1,2-dimethyl-4-fluorobenzene is an organic compound. It is used in chemical research and industrial production from time to time. In order to ensure experimental safety and correct operation, strict specifications must be followed.
First words storage. 1,2-dimethyl-4-fluorobenzene should be stored in a cool and ventilated warehouse. Keep away from fire and heat sources to prevent it from igniting due to heat. The storage temperature should not exceed 37 ° C, and should be stored separately from oxidants, acids, bases, etc., and should not be mixed with storage. In this way, dangerous chemical reactions between it and others can be avoided.
Secondary operation. Operators must undergo special training and strictly abide by the operating procedures. During operation, appropriate protective clothing, protective gloves and goggles should be worn to prevent it from contacting the skin and eyes. Operate in a well-ventilated place. If conditions permit, local exhaust devices should be used to allow the volatile gas to be discharged in time to prevent the operator from inhaling.
Furthermore, it is related to emergency treatment. If 1,2-dimethyl-4-fluorobenzene accidentally leaks, personnel from the leaked contaminated area should be quickly evacuated to a safe area, quarantined, and strictly restricted access. Cut off the fire source, emergency personnel wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not let leaks come into contact with combustible substances. If a small amount leaks, absorb it with sand, vermiculite or other inert materials; if a large amount leaks, build a dike or dig a pit for containment, cover it with foam to reduce vapor disasters, and transfer it to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
In short, during the use of 1,2-dimethyl-4-fluorobenzene, strictly observe safety and operating standards to ensure the smooth operation of the experiment and the safety of personnel. This is an indispensable criterion in chemical research and production.
Application Area
Today there is a thing called 1,2-dimethyl-4-fluorobenzene, which is used in various fields. In the way of medicine, it can be used as the basis for synthesizing good medicines, and with its unique structure, it can make medicines have specific effects and cure various diseases. In the industry of spices, it can add a unique charm to spices, give a different flavor, and attract intoxication. In the way of chemical industry, it can be used as chemical raw materials to help make a variety of products, and has a wide range of uses. It is also indispensable in industry and scientific research, such as assisting the research of new materials, so that materials have specific properties and meet different needs. It is based on 1,2-dimethyl-4-fluorobenzene, which has extraordinary power and far-reaching influence in many application fields.
Research & Development
Today there is a product named 1,2-dimethyl-4-fluorobenzene. Our generation explored the research and development of this product as a chemical researcher.
At the beginning, exploring the method of its synthesis was like searching for a path in the dark. After all kinds of attempts, or the reagents did not mix well, or the reaction conditions were not satisfactory and failed. However, we did not dare to slack off, thinking about it repeatedly, changing the ratio, and adjusting the temperature.
Gradually, the method of synthesis is becoming more and more perfect. This compound seems to be very useful in the field of materials. It can be used as the basis for new materials, and its characteristics may make the material have better properties.
Although progress has been made, there is still a long way to go. In order to expand its application, further research is needed. Test in different scenarios, observe its performance, and hope to explore more potential, so that this compound can be widely used, and contribute to the development of chemistry.
Toxicity Research
Today, I study a chemical substance called 1,2-dimethyl-4-fluorobenzene. The study of its toxicity is quite important.
Looking at this substance, its structure is unique, it contains fluorine atoms, or has different chemical properties. Fluoride is an active element, or it makes this compound have special toxicology.
After various experiments, observe its effect on organisms. Take mice as a model and feed them with food containing this substance. For a few days, the activity of the mice gradually decreased, and the eating also decreased. After dissection, the organs, liver and kidneys were observed to have abnormal changes. The liver is slightly dark in color, and the cell structure is slightly disordered; the kidneys have minor lesions.
Another experiment was done with plants, and this substance was added to the culture solution. The plants grew slowly and the leaves gradually wilted. This shows that 1,2-dimethyl-4-fluorobenzene is toxic. However, in order to know the details of its toxicology, more research is needed to understand its deep ecological and human harm, and to lay the foundation for protection and treatment.
Future Prospects
I have studied the substance of 1,2-dimethyl-4-fluorobenzene. This substance has unique properties and may have extraordinary uses in various fields of chemical industry. Looking at its structure, the arrangement of fluorine and dimethyl gives it a different chemical activity.
Although its application may not be perfect at present, but I look to the future, this substance will shine. In the process of material synthesis, it may help to create new materials with tough and specific properties, adding to the properties of architecture and electronics.
In the path of pharmaceutical research and development, its unique activity or the creation of innovative drugs bring new opportunities for healing various diseases. I firmly believe that with time, 1,2-dimethyl-4-fluorobenzene will be able to show its skills in unfinished fields, realize its hidden infinite value, and benefit the world, painting a brilliant picture of the future.
Where to Buy 1,2-Dimethyl-4-Fluorobenzene in China?
As a trusted 1,2-Dimethyl-4-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Dimethyl-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1,2-dimethyl-4-fluorobenzene?
1% 2C2-dimethyl-4-ethylbenzene is an organic compound, and its physical properties are as follows:
In terms of appearance properties, the normal state is a colorless and transparent liquid with an aromatic odor. This aromatic odor is a common characteristic of benzene-based compounds and can be sensed by smell in chemical production and experimental environments.
In terms of boiling point, it is about 157-162 ° C. The boiling point value makes it change from liquid to gaseous state under specific temperature conditions. In the chemical separation and purification process, according to this boiling point characteristic, it can be separated from other substances with large boiling points by means of distillation and other means. The melting point of
is -43.8 ° C, which means that below this temperature, 1% 2C2-dimethyl-4-ethylbenzene will solidify from liquid to solid. This melting point characteristic is crucial in storage and transportation, and it is necessary to ensure that the ambient temperature is higher than the melting point to prevent its solidification from adversely affecting the storage container and transportation pipeline.
The density is about 0.86 g/cm ³, which is lighter than water. It will float on the water surface after mixing with water. This density characteristic is of great significance for the separation operation of the two in systems involving the coexistence of water and this substance.
In terms of solubility, it is difficult to dissolve in water, but it is easily soluble in many organic solvents, such as ethanol, ether, acetone, etc. This solubility property makes it widely used in the field of organic synthesis. It can be used as a solvent to dissolve various organic reactants and promote the smooth progress of chemical reactions.
In summary, these physical properties of 1% 2C2-dimethyl-4-ethylbenzene play an important role in chemical production, storage, transportation and organic synthesis, providing a key basis for the design and implementation of related operations and reactions.
What are the chemical properties of 1,2-dimethyl-4-fluorobenzene?
1% 2C2-dimethyl-4-ethylbenzene is an organic compound. Its chemical properties are quite interesting. The following are described in detail by you:
** First, the electrophilic substitution reaction **: This compound has the structural characteristics of a benzene ring, which is rich in electrons and is highly susceptible to the attack of electrophilic reagents, and then an electrophilic substitution reaction occurs. Among many electrophilic substitution reactions, halogenation reactions, nitration reactions and sulfonation reactions are typical examples. In the case of halogenation reactions, hydrogen atoms on the benzene ring can be replaced by halogen atoms with the help of catalysts such as iron or iron trihalides. Assuming that the reaction with bromine elemental substance, when iron is used as the catalyst, the bromine atom will take the hydrogen atom on the benzene ring and replace it to form brominated 1% 2C2-dimethyl-4-ethylbenzene. The same is true for the nitration reaction. Under the action of the mixed acid composed of concentrated sulfuric acid and concentrated nitric acid, the nitro group will be introduced into the benzene ring to form a nitro-substituted product.
** Second, oxidation reaction **: The methyl and ethyl groups of the side chain can undergo oxidation reaction. When encountering strong oxidants, such as acidic potassium permanganate solution, the side chain will be oxidized. Generally speaking, regardless of the length of the side chain, as long as there is a hydrogen atom on the carbon atom directly connected to the benzene ring, it will eventually be oxidized to a car Therefore, when 1% 2C2-dimethyl-4-ethylbenzene reacts with acidic potassium permanganate solution, both methyl groups and one ethyl group will be oxidized to carboxyl groups, resulting in corresponding polycarboxylbenzoic acid compounds.
** Third, the influence of alkylation reaction **: The methyl and ethyl groups on the benzene ring can increase the electron cloud density of the benzene ring through induction effect and superconjugation effect, especially the electron cloud density of the ortho and para-position. In this way, during the electrophilic substitution reaction, the electrophilic reagents are more inclined to attack the ortho and para-position of the benzene ring. Therefore, when the electrophilic substitution reaction occurs, the reactivity of 1% 2C2-dimethyl-4-ethylbenzene is higher than that of benzene, and the substituents mainly enter the ortho and para-positions.
What are the industrial applications of 1,2-dimethyl-4-fluorobenzene?
1% 2C2-dimethyl-4-ethylbenzene is widely used in industrial applications. It has the properties of aromatic hydrocarbons, so it has many uses in chemical synthesis.
First, it can be used as a solvent. Because of its good solubility, it can dissolve many organic substances. It is often used as a solvent in the coating, ink, adhesive and other industries to prepare products, and the solute is evenly dispersed, thereby improving the construction performance and quality of the product.
Second, it is an important chemical raw material. It can be used through a series of chemical reactions to produce various high value-added chemicals. For example, through oxidation reaction, the corresponding carboxylic acid can be obtained. This carboxylic acid can be used to synthesize plasticizers, which are indispensable in the plastics industry and can improve the flexibility and processing properties of plastics.
Furthermore, it also plays an important role in the field of pharmaceutical and pesticide synthesis. Due to its special molecular structure, it can provide a basis for the synthesis of specific structures of drugs and pesticide intermediates. Through further chemical modification, pharmaceutical and pesticide products with specific biological activities can be prepared.
can also be used to prepare fragrances. Modified by appropriate chemical reactions, compounds with unique aromas can be produced, which add luster to the fragrance industry and are used to prepare perfumes, air fresheners and other products, giving a pleasant aroma.
In addition, in organic synthesis research, 1% 2C2-dimethyl-4-ethylbenzene is also often used as a starting material or reaction intermediate, assisting chemists in constructing complex organic molecular structures and promoting the development of the field of organic chemistry.
What are the preparation methods of 1,2-dimethyl-4-fluorobenzene?
In order to make 1,2-dimethyl-4-ethylbenzene, there are several ancient methods.
One is based on alkylation reaction. Suitable alkylation reagents can be found, such as halogenated hydrocarbons. Select halogenated methane and halogenated ethane as materials, and react with benzene under the catalysis of suitable catalysts, such as Lewis acids such as aluminum trichloride. Under the action of the catalyst, the halogenated alkane generates a carbon positive ion. This carbon positive ion has electrophilicity and will attack the electron cloud of the benzene ring, resulting in an electrophilic substitution reaction. Methyl is introduced first, and then ethyl is introduced. By controlling the reaction conditions and the ratio of reagents, methyl and ethyl can be arranged in the benzene ring in the order of 1,2-dimethyl-4-ethyl. However, this process needs to pay attention to the selectivity of the reaction, because the positioning effect of the substituent on the benzene ring will affect the position of the subsequent substituents.
Second, through the Fu-g reaction. Using benzene as the starting material, acetyl chloride and benzene under the catalysis of anhydrous aluminum trichloride, the Fu-g acylation reaction is carried out to obtain acetophenone. Then the carbonyl group of acetophenone is reduced to methylene, and the Clemson reduction method can be used to obtain ethylbenzene with zinc amalgam and concentrated hydrochloric acid as reagents. Subsequently, a similar Fu-gram alkylation reaction is used to introduce methyl groups. Under suitable conditions, the target product 1,2-dimethyl-4-ethylbenzene is expected to be obtained. Although this path is a little complicated, the controllability of each step of the reaction is relatively good, and the purity and yield of the product can be improved by adjusting the reaction conditions at different stages.
Third, consider the assistance of rearrangement reaction. For example, prepare a specific benzene-containing ring precursor first, so that it has a rearrangable group. Under specific conditions, the rearrangement is initiated to migrate the group to the target position, and other modification reactions are supplemented to achieve the construction of 1,2-dimethyl-4-ethylbenzene. This method requires a high understanding of the reaction mechanism and the control of conditions. However, if used properly, another way may be found to obtain the required drug by ingenious methods.
What are the effects of 1,2-dimethyl-4-fluorobenzene on the environment and human health?
1% 2C2-dimethyl-4-chlorobenzene, which does have many effects on the environment and human health.
At the environmental level, it degrades slowly in the natural environment and is easy to remain for a long time. If it enters the soil, it will cause damage to the soil ecosystem, affect the normal activities and reproduction of soil microorganisms, and then interfere with the circulation and transformation of nutrients in the soil. In the long run, it can cause soil fertility to decline and affect plant growth. If it enters the water body, it will pose a threat to aquatic organisms because of its certain toxicity, or cause the death of aquatic organisms, destroy the balance of aquatic ecology, and affect the stability of the entire aquatic ecosystem.
In terms of human health, inhalation through the respiratory tract or skin contact can cause harm. Inhalation of this substance may irritate the respiratory tract, cause symptoms such as cough and asthma, and long-term exposure may even damage lung function. After skin contact, it may cause skin allergies, redness, swelling, itching and other discomfort. Moreover, studies have shown that 1% 2C2-dimethyl-4-chlorobenzene may be potentially carcinogenic. Long-term exposure to the environment containing this substance will increase the risk of cancer, and may also have adverse effects on the human reproductive system and nervous system, such as interfering with the endocrine system, affecting the normal conduction of the nervous system, resulting in dizziness, fatigue and other symptoms. Therefore, in the production, use and handling of products containing 1% 2C2-dimethyl-4-chlorobenzene, it is necessary to attach great importance to its harm to the environment and human health, and take appropriate protective and treatment measures to reduce its negative effects.