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1,2-Dimethyl-3-Fluoro-6-Nitrobenzene

1,2-Dimethyl-3-Fluoro-6-Nitrobenzene

Hongda Chemical

Specifications

HS Code

691461

Chemical Formula C8H8FNO2
Molar Mass 169.153 g/mol
Appearance Solid (usually)
Solubility In Water Insoluble (due to non - polar aromatic nature and lack of strong hydrophilic groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene (due to its non - polar nature)
Vapor Pressure Low (due to its relatively high molecular weight and non - volatile nature)

As an accredited 1,2-Dimethyl-3-Fluoro-6-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2 - dimethyl - 3 - fluoro - 6 - nitrobenzene packaged in a sealed glass bottle.
Storage 1,2 - dimethyl - 3 - fluoro - 6 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Separate it from oxidizing agents, reducing agents, and other incompatible substances to prevent chemical reactions.
Shipping 1,2 - dimethyl - 3 - fluoro - 6 - nitrobenzene is a chemical. Ship it in sealed, corrosion - resistant containers, following hazardous materials regulations. Ensure proper labeling and transport by approved carriers to prevent leakage and risks.
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1,2-Dimethyl-3-Fluoro-6-Nitrobenzene 1,2-Dimethyl-3-Fluoro-6-Nitrobenzene
General Information
Historical Development
In the field of chemistry, new substances are produced, and 1,2-dimethyl-3-fluoro-6-nitrobenzene is also one of them. At the beginning of its inception, chemists worked hard to find a way to synthesize. At that time, technology was not as prosperous as it is today. All kinds of experiments were repeatedly wrong, and they were unremitting.
Over the years, the principles of organic synthesis have become more and more clear, and the technology has become more and more refined. In terms of reaction conditions and raw material proportions, detailed investigation was carried out, and a good method was finally obtained, so that the yield of this product gradually increased and the quality was also excellent.
From this perspective, the development of 1,2-dimethyl-3-fluoro-6-nitrobenzene really depends on the research of chemists in the past. In the course of historical evolution, it gradually shines brightly, adding to the grand cause of chemistry and paving the way for subsequent research.
Product Overview
1,2-Dimethyl-3-fluoro-6-nitrobenzene is an organic compound. Its shape may be crystalline, its color may be light, and it has a special taste.
This compound has a wide range of uses in the field of chemical synthesis. Its unique structure, fluorine, nitro and dimethyl positions affect its properties. Fluorine has strong electronegativity, which changes the polarity of molecules and has different chemical reactivity. Nitro has strong electron absorption, which decreases the electron cloud density of the benzene ring, decreases the activity of electrophilic substitution, and increases the activity of nucleophilic substitution.
The synthesis method often starts with specific benzene derivatives and is obtained by halogenation, nitration, alkylation and other reactions. Each step of the reaction requires controlled conditions, such as temperature, reagent ratio, catalyst, etc., to achieve high yield and purity.
In the chemical industry, pharmaceutical research and development, etc., 1,2-dimethyl-3-fluoro-6-nitrobenzene is an important medium, which can be derived from a variety of compounds with biological activity or special properties, promoting the progress of the industry.
Physical & Chemical Properties
1,2-Dimethyl-3-fluoro-6-nitrobenzene, the physical and chemical properties of this substance are related to many aspects. Its appearance may take a specific form, be crystalline, or be liquid, depending on the conditions. When it comes to physical properties, the melting point is the key indicator. When it comes to the melting point, the intermolecular forces play a key role, and the strength of the interaction varies. The boiling point is also affected by similar factors, which is related to the energy required for gasification.
Its chemical properties are active due to the presence of fluorine, nitro and other groups. Nitro has strong electron absorption, which changes the electron cloud density of the benzene ring and affects the activity of electrophilic substitution. Although fluorine atoms are small and have high electronegativity, they also affect the molecular reactivity. Under certain conditions, this substance may participate in many reactions, such as substitution, addition, etc., and has potential uses in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a product named 1,2-dimethyl-3-fluoro-6-nitrobenzene. In the field of chemical industry, process specifications and identification (commodity parameters) are the key.
To make this product, it is necessary to follow delicate process regulations. The choice of raw materials, when choosing pure, must be accurate. The reaction environment, temperature, pressure and other factors must be carefully controlled, the difference of the millimeter, or the change of the product.
As for the label, its characteristics, hazards and other commodity parameters should be detailed. State the chemical properties of this product, what kind of substances can react in case, whether it is toxic or corrosive, to warn everyone. In this way, it is possible to ensure the safety of this product in all aspects of production, transportation, and use, and also to ensure that the quality and application of this product are well-regulated and meet the high standards of the chemical industry.
Preparation Method
To prepare 1,2-dimethyl-3-fluoro-6-nitrobenzene, the method is as follows:
Raw materials and production process: Select xylene as the initial raw material, supplemented by fluoride, nitrifying reagents, etc. First mix in a specific ratio and prepare it in a special container.
Reaction steps: Put xylene in a reactor, control the temperature moderately, gradually add fluoride, catalyze the reaction, and obtain a fluorine-containing intermediate. After adjusting the temperature, add nitrifying reagents to introduce the nitro group into the predetermined position precisely.
Catalytic mechanism: Use a dedicated catalyst to reduce the reaction energy barrier, promote the reaction speed, and improve the product rate. Select a high-efficiency catalyst to increase the reaction activity and selectivity under mild conditions to avoid side reactions. In this way, 1,2-dimethyl-3-fluoro-6-nitrobenzene was prepared.
Chemical Reactions & Modifications
Recently, I have been researching the anti-chemical modification of 1,2-dimethyl-3-fluoro-6-nitrobenzene, and I am quite experienced. I would like to talk to you.
Those who are husband-chemical, explore the anti-chemical of matter. The anti-chemical process of this compound is like that of ancient times, and each atom and group is like that of a person, following the law. Its anti-chemical process, including nuclear substitution and addition, requires fine research, such as degree and catalysis, to obtain good results.
Modification, such as carving beautiful jade. Or introduce new radicals to reduce its properties and its new energy. With a certain catalytic system, the reaction can be made more efficient, and the properties of the substance can also be improved, the qualitative increase can be improved, and the activity can be controlled.
The wonder of the transformation is to explore the secret of the transformation of the substance, making this 1,2-dimethyl-3-fluoro-6-nitrobenzene more effective, just like the ancients did not expand the territory of the expansion.
Synonyms & Product Names
1,2-Dimethyl-3-fluoro-6-nitrobenzene, the synonym and trade name of this substance, is very important for chemical research. I have tried to study it carefully. Although the ancient books have not been accurately corresponding to the ancient name, I have deduced it from the current chemical theory. In this compound, "1,2-dimethyl" shows that there are dimethyl attached at the two positions above the benzene ring; "3-fluorine", which means that the three positions are connected by fluorine atoms; "6-nitro", indicating the existence of nitro at the six positions. Or according to its structural characteristics, the pseudo-synonym can be "dimethylfluoronitrobenzene isomer", and if the trade name is placed in the past, or according to the place where it was made and the method used, or it is intended to be "a special fluoronitroxylene in a certain place". Although there is no exact old name, it can be deduced by chemical knowledge, and it can also be briefly explored in the ancient chemical context.
Safety & Operational Standards
1,2-Dimethyl-3-fluoro-6-nitrobenzene is a chemical we are dedicated to studying. The safety and operating standards of this chemical are of paramount importance and cannot be slack.
This chemical has unique chemical properties. Its preparation, storage and use must be carried out according to precise specifications. When preparing, the ratio of various raw materials and the control of reaction conditions, such as temperature, pressure, reaction time, etc., need to be carefully controlled. A slight difference in the pool not only affects the purity and yield of the product, but also causes safety risks.
When storing, choose a suitable place. It is necessary to avoid open flames and hot topics to prevent them from being dangerous due to sudden temperature rises. And it should be placed separately from other chemicals such as oxidants and reducing agents to avoid improper contact and trigger violent reactions.
As for the use, the operator must be fully armed. Protective clothing, gloves, goggles, etc. are readily available to ensure that they are not exposed to chemicals. During the operation, the action should be steady and slow, and follow the established procedures. If there is waste generated, it should not be discarded at will. It should be properly disposed of according to environmental protection requirements to avoid polluting the environment.
In general, in the research and application of 1,2-dimethyl-3-fluoro-6-nitrobenzene, safety and operation standards are always followed. Only by strictly following this path can we ensure the smooth research, personnel safety and environment worry-free.
Application Area
1,2-Dimethyl-3-fluoro-6-nitrobenzene is also an organic compound. Its application field is quite extensive. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs or have unique effects on specific diseases. In materials science, it also has its application, which can contribute to the creation of new functional materials, such as improving the stability, conductivity and other special properties of materials. In the fine chemical industry, this compound can optimize product characteristics, such as improving the color fastness of dyes, or enhancing the durability of fragrances. Its application in many fields is waiting for our chemical researchers to continue to explore and explore, so as to make the best use of it and contribute to human well-being and technological progress.
Research & Development
Yu Taste is dedicated to the study of chemical substances, and recently focused on 1,2-dimethyl-3-fluoro-6-nitrobenzene. This substance has a unique structure and specific properties.
I began to study the synthesis path of this substance, and consulted many ancient books and modern studies to find the best method. After repeated experiments, the proportion of raw materials, reaction temperature and duration were adjusted, and a stable synthesis scheme was gradually obtained.
When studying its properties, observe its physical properties, such as color, odor, melting and boiling point, etc. Also explore its chemical activity, react with various reagents, and remember the phenomenon and product in detail. Through this process, I have a deeper understanding of its reaction law.
Looking to the future, I hope to expand the application field of this substance. Or in material science, give materials new properties; or in drug research and development, seek new opportunities. Unremitting research can contribute to the development of chemistry, and promote this substance from research to wide application and use by the world.
Toxicity Research
In recent years, Yu devoted himself to the study of chemical substances, especially the investigation of the toxicity of 1,2-dimethyl-3-fluoro-6-nitrobenzene. Although this substance is widely used, its potential harm has not been investigated in detail.
Observe the structure of its molecules, the genus of fluorine and nitro, or the change of biological activity. In the experiment, various species of organisms were used as samples to measure their reactions. At low concentrations, there are also differences in biochemical indicators, and the state and metabolic process of cells are disturbed.
And it enters the environment, or accumulates in water and soil, and then enters the food chain. Although the long-term harm of this substance is not yet known, the toxicity cannot be ignored based on the current fruit. In the future, we should expand the research path, explore the principle of its function, and find ways to protect and resolve it, so as to ensure the safety of all living beings and the environment.
Future Prospects
Prospects of the future, in the 1,2-dimethyl-3-fluoro-6-nitrobenzene, it is not a problem. It has important angles in synthesis, and can develop new ways. Or in the field of research, to help research special effects, to solve the pain of disease. Or in the material industry, it is a novel thing, and the new energy of the material.
Today's research has proved that its properties are not the same. However, there is no way to do it, and there is no need to wait. Hope to be able to refine its method, improve the cost and increase the cost, and reduce the cost and increase the efficiency. We also hope to explore its new uses, so that this material can be used in more fields, shining brightly, promoting the development of science and technology, for the benefit of life, and to achieve a better environment. This is the aspiration of our researchers, and it is not yet expected.
Where to Buy 1,2-Dimethyl-3-Fluoro-6-Nitrobenzene in China?
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Frequently Asked Questions

As a leading 1,2-Dimethyl-3-Fluoro-6-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-dimethyl-3-fluoro-6-nitrobenzene?
1% 2C2-dimethyl-3-pentene-6-alkynylbenzene, which has the characteristics of alkenes and alkynes, has a wide range of uses in the field of organic synthesis.
One of them can be used as a key building block for the construction of complex organic molecules. Because its alkynyl structure is rich in reactive activity check points, chemists can skillfully integrate it into larger molecular structures through various organic reactions, such as addition and cyclization. For example, in the Diels-Alder reaction, the double bond of the compound can be cyclized and added to the conjugated diene to form a product with a special carbon ring structure. This product is often an important intermediate in the total synthesis of natural products and drug research and development.
Second, it also has extraordinary performance in the field of materials science. Due to its unique unsaturated bond structure, polymer materials with specific properties can be prepared by polymerization. For example, with an appropriate initiator, the alkyne bond can be polymerized to form a polymer with special optical and electrical properties, or it can be used in the field of optoelectronic materials, such as the manufacture of organic Light Emitting Diode (OLED), solar cells and other devices.
Third, in the field of medicinal chemistry, this compound may be used as a lead compound for structural modification and optimization. Its unsaturated bond can be used as a key part of the pharmacophore, interacting specifically with biological targets, laying the foundation for the development of new drugs. Chemists can adjust its physicochemical properties and biological activities by introducing different substituents based on this structure, hoping to obtain drugs with better efficacy and less side effects.
What are the physical properties of 1,2-dimethyl-3-fluoro-6-nitrobenzene?
1% 2C2-dimethyl-3-pentene-6-alkynylbenzene is an organic compound with unique physical properties. In the era of Tiangong Kaiwu, although it is difficult to have an accurate understanding, with today's scientific knowledge, it can be described as follows:
Its appearance may be a colorless to light yellow liquid with a special odor. Due to the double and triple bonds of carbon, it has a certain degree of unsaturation. In the molecular structure, the presence of benzene rings makes it aromatic, which affects the physical and chemical properties of the compound.
In terms of boiling point, due to intermolecular forces including van der Waals force and π-π accumulation, its boiling point may be affected by the size, shape and functional group of the molecule. Usually compounds containing such unsaturated bonds and benzene rings have boiling points or within a certain range, but the exact value varies depending on the specific structure.
In terms of solubility, according to the principle of similarity dissolution, it is a non-polar or weakly polar compound. It has good solubility in non-polar or weakly polar organic solvents such as hexane and toluene. It is difficult to dissolve in water with strong polarity because it cannot form an effective interaction with water molecules.
The density may be slightly higher than that of water. Due to the relative mass and close arrangement of carbon and hydrogen atoms in the molecule, the unit volume mass is larger.
The refractive index is also an important physical property, which is related to the distribution and structure of the electron cloud of the molecule. It can be used for the purity and identification analysis of compounds. Contains conjugated double bonds and benzene ring structure, or makes the refractive index have a specific value, reflecting the influence of molecules on the direction of light propagation.
In addition, due to unsaturated bonds, the compound has high reactivity and is prone to reactions such as addition and oxidation, which has important application value in the field of organic synthesis. Although this specific compound is not listed in "Tiangong Kaiji", it can be understood by today's scientific understanding that its physical properties provide a basis for research and application.
What is the chemical synthesis method of 1,2-dimethyl-3-fluoro-6-nitrobenzene?
To prepare 1,2-dimethyl-3-ethyl-6-isopropylbenzene, the following method can be followed.
First take a suitable aromatic hydrocarbon raw material, and choose benzene or its simple alkyl derivatives. If benzene is used as the starting point, a multi-step reaction is required to introduce the desired substituent.
The first step is to introduce ethyl. The Fu-gram alkylation reaction can be used to react chloroethane with benzene under the catalysis of anhydrous aluminum trichloride to obtain ethylbenzene. In this reaction, anhydrous aluminum trichloride acts as a catalyst to promote the electrophilic substitution of chlorine atoms and benzene rings in chloroethane, and ethyl groups are attached to the benzene rings.
The second step is to introduce isopropyl on the basis of ethylbenzene. The Fu-gram alkylation reaction is still used, and the isopropyl chloride reacts with ethylbenzene under the catalysis of anhydrous aluminum trichloride. The chlorine in the isopropyl chloride is attracted by the ethylbenzene ring, which undergoes electrophilic substitution, and the isopropyl is connected to the benzene ring to obtain ethylisopropylbenzene.
The third step is to introduce two more methyl groups. A suitable methylating agent, such as iodomethane, can be used to react with ethylisopropylbenzene under suitable basic conditions and in the presence of a catalyst. The alkali can promote the formation of carbon negative ions from methyl groups in iodomethane. This carbon negative ion undergoes nucleophilic substitution of benzene ring, and two methyl groups are introduced successively to obtain 1,2-dimethyl-3-ethyl-6-isopropylbenzene.
During the reaction process, attention should be paid to the control of the conditions of each step of the reaction, such as temperature and catalyst dosage, etc., to ensure that the reaction proceeds in the direction of the desired product and reduce the occurrence of side reactions. After the completion of each step of the reaction, it needs to go through steps such as separation and purification to obtain a pure product. In this way, the target compound 1,2-dimethyl-3-ethyl-6-isopropylbenzene can be synthesized according to the above method.
What are the precautions for storing and transporting 1,2-dimethyl-3-fluoro-6-nitrobenzene?
When storing and transporting 1% 2C2-dimethyl-3-chloro-6-cyanopyridine, pay extra attention to the following things:
First, the storage place should be dry and cool. This compound is susceptible to changes in properties due to water vapor. If the moisture is too heavy, or it causes chemical reactions such as hydrolysis, it will damage its quality. Therefore, it should be placed in a dryer or sealed container and stored in a well-ventilated and low temperature place to prevent its decomposition or volatilization from being exacerbated due to excessive temperature.
Second, strictly adhere to the principle of sealing. Be sure to ensure that the packaging is tight and avoid excessive contact with the air. Due to oxygen, carbon dioxide and other components in the air, or react with it. Sealed storage can reduce its interaction with external substances and ensure its chemical stability.
Third, when transporting, it is necessary to choose suitable packaging materials. According to its characteristics, choose materials with good corrosion resistance and sealing, such as special plastic containers or glass containers, and supplemented by buffer materials to prevent packaging damage and leakage caused by transportation bumps.
Fourth, classified storage and transportation. Do not mix and transport with oxidants, reducing agents, acids, alkalis and other substances. 1% 2C2-dimethyl-3-chloro-6-cyanopyridine is chemically active, contact with the above substances, or react violently, leading to safety accidents.
Fifth, follow relevant regulations and standards. Whether it is storage or transportation, it must comply with relevant national and industry norms, such as standards for the storage and transportation of hazardous chemicals, to ensure the safety of personnel and the environment from pollution.
What are the effects of 1,2-dimethyl-3-fluoro-6-nitrobenzene on the environment and human health?
1% 2C2-dimethyl-3-ethyl-6-nitropyridine This substance has various effects on the environment and human health, as detailed below:
Effect on the environment
- ** Water pollution **: If this substance flows into rivers, lakes and seas and other waters, it will persist in the water body for a long time due to its difficult degradation characteristics. It may change the chemical properties of the water body, cause the pH imbalance of the water body, and hinder the living environment of aquatic organisms. And because it is toxic, or directly poisons fish, shrimp and crabs and other aquatic animals, causing their death or sharp decline in population; it may also affect the photosynthesis and growth and reproduction of algae and other plankton, destroy the food chain and energy transfer of the aquatic ecosystem, and cause the entire aquatic ecosystem to be unbalanced.
- ** Soil pollution **: If the waste contaminated with this substance enters the soil, it will reduce soil fertility, change soil structure, and inhibit the activity and reproduction of microorganisms in the soil. If the plant root system absorbs the soil nutrients containing this substance, it will not only affect its own growth and development, but also cause slow growth, withering, etc., and may also pass through the food chain, causing indirect harm to animals and even humans that feed on plants.
- ** Air pollution **: If this substance evaporates into the atmosphere, it will photochemically react with other chemicals in the atmosphere to generate secondary pollutants, such as ozone, which will exacerbate the degree of air pollution, reduce air quality, and may also have a certain impact on the regional climate.
Effects on human health
- ** Acute poisoning **: If people inhale high concentrations of 1% 2C2-dimethyl-3-ethyl-6-nitropyridine for a short time, it can irritate the respiratory mucosa, causing cough, asthma, breathing difficulties and other symptoms. If ingested carelessly, it can damage the digestive system, causing nausea, vomiting, abdominal pain, diarrhea, etc. In severe cases, it can cause coma, shock, and life-threatening.
- ** Chronic Poisoning **: Long-term exposure to low concentrations of this substance can cause damage to the nervous system, causing headaches, dizziness, fatigue, insomnia, memory loss and other neurasthenia symptoms. At the same time, it may affect the human immune system, reduce the body's resistance, and make people more susceptible to various diseases. In addition, studies have shown that this substance may be carcinogenic, and long-term exposure will increase the risk of cancer, such as lung cancer, liver cancer, etc.