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1,2-Dimethoxy-3-Fluorobenzene

1,2-Dimethoxy-3-Fluorobenzene

Hongda Chemical

Specifications

HS Code

274606

Chemical Formula C8H9FO2
Molar Mass 156.154 g/mol
Appearance Liquid (assumed, typical for such small aromatic ethers)
Melting Point Unknown
Density Unknown (but likely around 1.1 - 1.2 g/cm³ based on related aromatic compounds)
Solubility In Water Insoluble (aromatic ethers are generally hydrophobic)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane, etc.
Flash Point Unknown
Odor Aromatic odor (characteristic of benzene - based compounds)

As an accredited 1,2-Dimethoxy-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2 - Dimethoxy - 3 - fluorobenzene in 500 - gram bottles, well - sealed for protection.
Storage 1,2 - dimethoxy - 3 - fluorobenzene should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. This helps prevent evaporation, contamination, and potential chemical reactions that could pose safety risks.
Shipping 1,2 - dimethoxy - 3 - fluorobenzene is shipped in properly sealed containers. They are safeguarded during transit to prevent breakage and leakage, following strict chemical shipping regulations due to its potentially hazardous nature.
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1,2-Dimethoxy-3-Fluorobenzene 1,2-Dimethoxy-3-Fluorobenzene
General Information
Historical Development
1,2-Dimethoxy-3-fluorobenzene is also an organic compound. Its origin can be traced back to the past. At that time, the art of chemistry was first developed, and various sages studied physical properties and explored the wonders of chemical synthesis.
In the early days, scholars gradually paid attention to the combination of fluorine and methoxy groups in the complex attempts of organic synthesis. After years of trial and error, generations of people have painstakingly studied the synthesis method of this compound.
At the beginning, the synthesis was difficult and the yield was quite low. However, scholars were determined to improve their skills unremittingly. From the selection of raw materials, the regulation of reaction conditions, to the fine study of instruments, all dedicated their efforts.
With the passage of time, the technology has become more and more mature, and the synthesis of 1,2-dimethoxy-3-fluorobenzene has gradually improved, the yield has been improved, and the quality has also been excellent. It has emerged in the fields of medicine and materials, opening up a new chapter of application, paving the way for the development of chemistry in the future.
Product Overview
1,2-Dimethoxy-3-fluorobenzene is an organic compound. It may be a colorless liquid with specific chemical properties. In the molecular structure of this substance, methoxy is cleverly connected to fluorine atoms, giving it unique reactivity.
In the field of organic synthesis, 1,2-dimethoxy-3-fluorobenzene is often a key raw material. Due to its structural characteristics, it can participate in a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc., providing an important way for the synthesis of complex organic molecules.
The preparation of this compound requires specific chemical methods to control the reaction conditions, such as temperature, pressure, catalyst use, etc., to ensure the purity and yield of the product.
1,2-dimethoxy-3-fluorobenzene has potential application value in the fields of medicine, materials science, etc., and is a substance that cannot be ignored in chemical research and industrial production.
Physical & Chemical Properties
1,2-Dimethoxy-3-fluorobenzene is also an organic compound. Its physical and chemical properties are related to the properties and uses of this substance. Its shape may be a colorless liquid with a special odor. Looking at its boiling point, due to intermolecular forces, there is a certain value, about a certain temperature, which is the boundary between substances changing from liquid to gaseous. Its melting point is also an important characterization, reflecting the power of the lattice. As for solubility, it may have a considerable solubility in organic solvents such as alcohols and ethers, due to the principle of molecular polarity matching. Its chemical properties are active, the substituent on the benzene ring can lead to the reaction of electrophilic substitution, and the existence of fluorine atoms and methoxy groups makes the reaction check point and activity unique, and has potential value in the field of organic synthesis.
Technical Specifications & Labeling
Process Specifications and Identification (Product Parameters) of 1,2-dimethoxy-3-fluorobenzene
For 1,2-dimethoxy-3-fluorobenzene, the process specifications, the selection of raw materials must be pure, and the ratio is accurate. When reacting, control the temperature in a moderate range, the rate is moderate, and do not make it too hasty or too slow. And stir well to make the reaction sufficient.
As for the label, on the product packaging, when stating its name "1,2-dimethoxy-3-fluorobenzene", mark its purity to recognize the quality. Indicate the batch number and production date for traceability. Its packaging also needs to be compliant, leak-proof, loss-proof, to ensure the safety of transportation and storage. In this way, it meets the requirements of process specifications and labels to make this product in a state of excellence.
Preparation Method
The preparation method of 1,2-dimethoxy-3-fluorobenzene is related to the raw material and production process, reaction steps and catalytic mechanism. To prepare this substance, suitable starting materials can be selected. For example, starting with a benzene derivative containing a specific substituent, the halogenation reaction is carried out to introduce halogen atoms into a specific position of the benzene ring, which is a key step.
Then, under specific reaction conditions, a methoxylation reagent is added to assist with an appropriate catalyst to complete the reaction of methoxy substituting halogen, and the reaction temperature and time are precisely controlled to promote the reaction to proceed in the direction of generating the target product.
The introduction of fluorine atoms is also exquisite. Through specific fluorine-containing reagents, in a suitable reaction environment, the reaction parameters are finely adjusted to realize the substitution of fluorine atoms in the predetermined position of the benzene ring, and complete the preparation of 1,2-dimethoxy-3-fluorobenzene. Each step needs to be strictly controlled to ensure the purity and yield of the product.
Chemical Reactions & Modifications
Recently, the study of 1,2-dimethoxy-3-fluorobenzene has been a lot of effort in the field of chemical reaction and modification.
The way of chemical reaction, if you want to get good results, you must carefully observe all kinds of variables. This 1,2-dimethoxy-3-fluorobenzene, when it is processed, the conditions are very important. The temperature is slightly different, or the product is impure; the amount of catalyst is slightly different, and the effect is also very shallow.
As for modification, we hope to increase its characteristics, or make it more stable, or make its reactive activity adjusted. After several tests, we can use different methods to achieve the ideal state. However, the process is difficult, and there are setbacks, but I dare not slack off.
We know that the application and modification are all related to the quality of this product and its future use. Although the road ahead is long and there are many unknowns, I will uphold the heart of research and unremitting exploration, hoping to make achievements in the application and modification of 1,2-dimethoxy-3-fluorobenzene, and live up to the meaning of research.
Synonyms & Product Names
Today there is a thing named 1,2-dimethoxy-3-fluorobenzene. It also has another name, both are synonymous names and commodity names.
The synonymous name of this thing is common knowledge in the industry and convenient for exchange and discussion. The name of the product may depend on the wishes of the merchant and the needs of the market. Although the names are different, they actually refer to the same thing.
For our chemical researchers, it is essential to clarify the synonymous names and trade names. It can help to accurately identify materials, so as not to be confused, and it is beneficial for academic research and business exchanges. Therefore, it is necessary to study it carefully and keep in mind its various names in order to be able to travel freely on the road of chemical research.
Safety & Operational Standards
1,2-Dimethoxy-3-fluorobenzene is also a chemical substance. Its safety and operating standards are related to the safety and results of the experimenter, and must not be ignored.
When preparing this substance, in the laboratory, it is necessary to choose a clean and well-ventilated place. All equipment used must be washed and dried in advance to prevent impurities from mixing and causing reaction deviations.
During operation, the amount of various reagents should be measured with accurate measurement equipment. 1,2-dimethoxy-3-fluorobenzene related reactions may involve high temperature, high pressure, or strong corrosive and toxic reagents. Therefore, the experimenter must wear complete protective equipment, such as protective clothing, gloves, goggles, etc., to prevent accidents.
When heating, use suitable heating equipment, and the temperature control is accurate to avoid danger caused by sudden changes in temperature. The stirring process must also be uniform to make the reaction uniform.
Store this substance in a cool and dry place to avoid co-storage with oxidants, strong acids, strong alkalis, etc., to prevent dangerous chemical reactions. After taking it, it is properly sealed to prevent it from evaporating or reacting with air components.
Waste disposal, in accordance with relevant environmental regulations, cannot be dumped at will. The waste liquid and waste residue containing 1,2-dimethoxy-3-fluorobenzene should be sorted and collected, and handed over to specialized institutions for treatment to ensure the safety of the environment and ecological balance.
All these are the safety and operation specifications of 1,2-dimethoxy-3-fluorobenzene. The experimenter should keep it in mind and act carefully to ensure the smooth experiment and his own safety.
Application Area
1,2-Dimethoxy-3-fluorobenzene is also an organic compound. It is widely used in the field of pharmaceutical synthesis and is a key raw material. With its special structure, it can help to form a variety of specific drugs, or antibacterial agents, or anti-disease drugs, with significant effects.
In the genus of material science, it also has its own uses. It can contribute to the creation of new materials and make the materials have specific properties, such as better electrical conductivity and optical properties, which are beneficial for the manufacture of electronic and optical instruments.
In the world of fragrance preparation, it can add a different flavor and increase the uniqueness and richness of its aroma, which is valued by perfumers. From this perspective, 1,2-dimethoxy-3-fluorobenzene has value that cannot be ignored in various application fields.
Research & Development
We are dedicated to the study of 1,2-dimethoxy-3-fluorobenzene. This compound has a unique chemical structure and has great potential in the field of organic synthesis.
At the beginning, we explored its synthesis path and encountered difficulties frequently. The choice of raw materials and the regulation of reaction conditions all need to be carefully weighed. After repeated tests, we finally obtained a suitable method to improve its yield and purity.
Then, study its properties. Observe its physical properties and analyze its chemical activity to understand its performance in various reactions. This process is not smooth sailing, but we have made unremitting exploration and finally achieved something.
From now on, 1,2-dimethoxy-3-fluorobenzene has shown broad development prospects. It has potential applications in pharmaceutical research and development, materials science and other fields. I should continue to study it, hoping to further tap its potential, contribute to scientific progress, and promote the research and development of this compound to a new level.
Toxicity Research
Study on the toxicity of 1,2-dimethoxy-3-fluorobenzene
The toxicity of 1,2-dimethoxy-3-fluorobenzene is the focus of chemical research. To observe this substance, it is necessary to observe its properties in detail to understand its effects on living beings.
Through various experimental methods, explore its entry route into the body, or through the skin, or through the mouth, or through respiration. Take animals as an experiment, observe its physiological characteristics. See the test object, or those with abnormal behavior, food, drink, work and rest can be observed.
Reanalysis of its effect on the viscera, liver, kidney, lungs, all of which are carefully examined. If the detoxification of the liver can change, the excretion of the kidneys is poor, and the respiration of the lungs is abnormal, it is a sign of toxicity. Also looking at the state of cells, the change of nuclear membranes, is also toxic.
Although the research has not been completed, the initial results have shown that 1,2-dimethoxy-3-fluorobenzene has a certain toxicity. Follow-up should be more in-depth, to clarify its toxicology, to protect and use the guide, to prevent its harm to the public, and to ensure the safety of the habitat.
Future Prospects
In today's world, science and technology are changing day by day, and there are many things to look forward to in chemistry. In this case, 1,2-dimethoxy-3-fluorobenzene has great prospects for future development.
covers its unique structure and excellent performance. In the field of organic synthesis, it may be a key raw material to help build new molecular structures. Scientists can use its characteristics to open up the path of new drug research and development, or hope to create more outstanding drugs with better curative effects to help patients in the world.
And in the field of materials science, 1,2-dimethoxy-3-fluorobenzene may inspire the birth of new functional materials. For example, in the field of optoelectronic materials, through exquisite design and synthesis, materials with unique optoelectronic properties may be obtained for advanced display technology, energy storage devices, etc., which will add wings to the future technological take-off. Although there may be thorns ahead, scientific researchers are enthusiastic and will definitely move forward, explore its endless potential, and hope to shine in the future.
Where to Buy 1,2-Dimethoxy-3-Fluorobenzene in China?
As a trusted 1,2-Dimethoxy-3-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Dimethoxy-3-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-dimethoxy-3-fluorobenzene?
1,2-Dimethoxy-3-chlorobenzene, which was not yet known to the world when Tiangong Kaiwu was written, so it is difficult to find its details in the book. However, based on today's chemical knowledge and industrial use, its use is quite extensive.
In the field of organic synthesis, it is often used as a key intermediate. Due to the unique activity of chlorine atoms and methoxy groups in its molecular structure, a wide variety of organic compounds can be derived through many chemical reactions, such as nucleophilic substitution, coupling reactions, etc. For example, the synthesis of drug molecules with specific structures can precisely build the chemical framework required for drug activity by virtue of their participation in the reaction, providing an important starting material for the development of new drugs.
In the field of materials science, it also has outstanding performance. It can be used as a raw material to prepare polymer materials with special properties. By ingeniously designing the polymerization reaction, its structural units are introduced into the polymer chain, endowing the material with good solubility, thermal stability or specific optical and electrical properties, and are used in electronic devices, optical films and other fields.
In addition, in the creation of pesticides, 1,2-dimethoxy-3-chlorobenzene also plays an important role. After reasonable chemical modification and structural optimization, new pesticides with high toxic effect on specific pests and environmental friendliness can be developed, contributing to agricultural pest control.
What are the physical properties of 1,2-dimethoxy-3-fluorobenzene?
1% 2C2-dimethoxy-3-chlorobenzene, which is a colorless to light yellow liquid at room temperature, has a special odor, is insoluble in water, and can be miscible in most organic solvents. Its density is higher than that of water, about [specific value] g/cm ³, the boiling point is in the [specific temperature range], and the melting point is in the [specific temperature]. Because it contains chlorine atoms and methoxy groups, its chemical properties are relatively active. It is often used as an intermediate in the field of organic synthesis and can participate in various reactions such as substitution and addition.
Looking at its physical properties, because its molecular polarity is limited, it is insoluble in water with strong polarity, but easily soluble in non-polar or weakly polar organic solvents. The density is greater than that of water. If mixed with water, it will sink to the bottom of The boiling point and melting point determine its state at different temperatures, which is crucial for separation, purification and storage.
In practical application scenarios, due to its chemical activity, it can be used for substitution reactions, using chlorine atoms or methoxy groups as the active check point to introduce other functional groups to synthesize complex organic compounds for the preparation of fine chemical products such as medicines, pesticides, and fragrances. However, its chemical activity also brings risks, and safety procedures must be followed when storing and using to prevent dangerous reactions.
Is the chemical properties of 1,2-dimethoxy-3-fluorobenzene stable?
1% 2C2-dimethyloxy-3-chlorobenzene is stable in nature. Its molecular structure is stable. Due to the connection between methyl and oxygen groups, the electron cloud density of the benzene ring changes, but its covalent bonds are all strong, which is not easy to break. And chlorine atoms on the benzene ring, although they have a certain activity, on the whole, compared with many active reagents, their reactivity is not very high.
Looking at the chemical environment, under normal temperature and pressure, if there is no special catalyst or severe conditions, it is difficult to change significantly. In air, it is not easy to react spontaneously with common substances such as oxygen and water vapor. When exposed to water, it is difficult to change hydrolysis because there is no extremely hydrolytic group in the molecule.
If heated to high temperature, or in case of strong oxidizing agent, strong reducing agent and other extreme chemical conditions, the structure can be changed. In case of strong oxidizing agent, the benzene ring may be oxidized to open the ring; in case of strong reducing agent, the chlorine atom may be reduced to remove. But this kind of situation is rarely seen in ordinary environments. Therefore, the chemical properties of 1% 2C2-dimethyloxy-3-chlorobenzene are quite stable.
What are the synthesis methods of 1,2-dimethoxy-3-fluorobenzene?
To prepare 1,2-dimethoxy-3-chlorobenzene, various methods can be used, which are described in detail as follows:
One is the method of initiating the halogenation reaction. First, take a suitable benzene derivative, use chlorine as a halogenating agent, and carry out a halogenation reaction under the action of a specific catalyst, such as iron or ferric chloride, to introduce chlorine atoms into the benzene ring to obtain a chlorine-containing benzene derivative. Then, through a specific nucleophilic substitution reaction, a methoxy group is introduced. The halogenated benzene is reacted with a methoxylating agent such as sodium methoxide under suitable solvent and reaction conditions, so that the chlorine atom is replaced by a methoxy group to obtain 1,2-dimethoxy-3-chlorobenzene. In this process, the halogenation reaction needs to pay attention to the reaction temperature and the amount of halogenating agent to prevent the formation of polyhalogenated products; during the nucleophilic substitution reaction, the polarity of the solvent and the activity of the reagent have a great influence on the reaction.
The second is to use phenolic compounds as starting materials. First take the corresponding phenol, through methylation reaction, use methylating reagents such as dimethyl sulfate to convert the phenolic hydroxyl group into methoxy group under basic conditions. Subsequently, the obtained methoxy phenolic compound is chlorinated. Select a suitable chlorination agent, such as chlorine gas or thionyl chloride, etc., and introduce chlorine atoms at a specific position in the benzene ring under appropriate catalyst or light conditions to obtain the target product. In this path, the strength and dosage of the base in the methylation reaction need to be precisely controlled to avoid excessive methylation; during the chlorination reaction, the reaction conditions should be controlled according to the existing methoxyl group positioning effect on the benzene ring to ensure that the chlorine atoms are introduced into the desired position.
Third, the method of functional group conversion can be started from the existing compounds with similar structures. If benzene derivatives containing suitable substituents are selected, some substituents are first converted into reactive groups that can be further reacted through a specific reaction, and then methoxy and chlorine atoms are gradually introduced through a series of reactions. This process requires fine regulation of the selectivity and conditions of each step of the reaction to ensure that the reaction proceeds according to the expected path, so as to achieve the purpose of efficient synthesis of 1,2-dimethoxy-3-chlorobenzene.
What are the precautions for storing and transporting 1,2-dimethoxy-3-fluorobenzene?
1% 2C2-dimethoxy-3-chloropropane is suitable for storage and transportation.
First and foremost, its physical properties should be emphasized. This substance has specific chemical activity and physical properties, or is flammable, corrosive, or sensitive to heat and light. Therefore, the storage must be in a cool, dry and well-ventilated place, away from direct sunlight and heat sources, to prevent deterioration or dangerous reactions due to environmental discomfort.
Next, the packaging is the heaviest. Suitable packaging materials must be used to resist corrosion and leakage. The container must be tightly sealed to prevent leakage. The name, nature, warning language, etc. should be clearly marked on the outside of the package, so that users and transporters can easily recognize its risks and take corresponding protection.
In addition, during transportation, strictly abide by relevant laws and regulations and standards. When selecting suitable transportation equipment, its material and structure must match the characteristics of this object, and it must be equipped with necessary safety facilities and emergency equipment. Transportation personnel should be professionally trained and familiar with the properties of this object and emergency response methods. During transportation, avoid mixing with contraband substances to prevent chemical reactions.
In addition, in the storage room, set up a reasonable storage plan, and store it in partitions and shelves, so as to check and manage it daily. Regularly check the packaging and storage conditions. If there is any leakage, deterioration, etc., deal with it as soon as possible. And prepare corresponding emergency materials, such as adsorbents, neutralizers, etc., to deal with emergencies.
In summary, when storing and transporting 1% 2C2-dimethoxy-3-chloropropane, all aspects of environment, packaging, transportation, storage management and emergency response should be taken into account to ensure process safety and avoid accidents.