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1,2-Difluoro-4-(Trifluoromethyl)Benzene

1,2-Difluoro-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    910925

    Chemical Formula C7H3F5
    Molar Mass 182.09 g/mol
    Appearance Colorless liquid
    Boiling Point 113 - 114 °C
    Density 1.358 g/cm³
    Solubility In Water Insoluble
    Flash Point 17 °C
    Refractive Index 1.379

    As an accredited 1,2-Difluoro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2 - difluoro - 4 - (trifluoromethyl)benzene in 500 mL glass bottle for chemical storage.
    Storage 1,2 - difluoro - 4 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat and ignition sources. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Ensure the storage facility has secondary containment to handle potential spills safely.
    Shipping 1,2 - difluoro - 4 - (trifluoromethyl)benzene is shipped in sealed, corrosion - resistant containers. It follows strict chemical transportation regulations to ensure safety during transit, avoiding exposure to heat, sparks, and incompatible substances.
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    1,2-Difluoro-4-(Trifluoromethyl)Benzene 1,2-Difluoro-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1,2-Difluoro-4- (trifluoromethyl) benzene is also an organic compound. At the beginning of its origin, chemists paid attention to this unique structure when they were exploring various fluorides.
    At that time, science was not as bright as it is today, and research was difficult. However, the public worked tirelessly to use simple tools and basic methods to gradually understand its properties.
    With the passage of time, technology has advanced day by day. The more refined the analysis method, the more detailed it can be, the molecular structure and physicochemical properties can be measured. The synthesis method has also evolved, from the initial complicated and inefficient, to the later concise and efficient, and the yield has gradually increased.
    Today, this compound is widely used in many fields such as medicine and materials. Looking at its historical development, it is the condensation of the wisdom and hard work of chemists and the evidence of scientific progress.
    Product Overview
    1,2-Difluoro-4- (trifluoromethyl) benzene is an important product of organic chemistry. Its color is clear, its shape is like a liquid, and its taste is slight. Looking at the structure of its molecules, on the benzene ring, fluorine and trifluoromethyl are ordered, resulting in its unique physicochemical properties.
    This product has high chemical activity and has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate, involving the preparation of drugs, pesticides and functional materials. For example, in pharmaceuticals, its structural characteristics can help to precisely design drug molecules and improve curative effect.
    The method of preparation involves several steps of reaction, starting with specific halogenated aromatics, fluorine borrowing, substitution and other reactions. However, the preparation process requires strict control of conditions, such as temperature and the amount of catalyst, in order to ensure the purity of the product and the high yield.
    In storage and transportation, because of its certain volatility and chemical activity, it is necessary to use sealing and low temperature methods to avoid contact with oxidants, bases and other substances to prevent danger. In short, 1,2-difluoro-4- (trifluoromethyl) benzene has a significant position in the chemical industry and has broad prospects.
    Physical & Chemical Properties
    Today there is a substance named 1,2-difluoro-4- (trifluoromethyl) benzene. Its physical properties are colorless and transparent at room temperature, similar to water but light in weight, and its density is smaller than that of water, between about 0.9 and 1.1 grams per cubic centimeter. Its gas is slightly aromatic, but it cannot be smelled close to it, and it has a certain volatility. The melting point is also different from that of normal substances. The melting point is about tens of degrees below zero, and the boiling point is in the hundreds of degrees.
    In terms of its chemical properties, it is quite active. Its benzene ring structure is easy to electrophilic substitution. When it encounters a halogenating agent, it can undergo a halogenation reaction; when it encounters a nitrifying agent, it can also form a nitro compound. And due to the introduction of fluorine and trifluoromethyl, the distribution of electron cloud changes, causing its reactivity to increase or decrease compared with benzene. Its fluorine-containing structure makes this substance have certain chemical stability and can resist the erosion of some reagents. It may be useful in various fields of chemical industry.
    Technical Specifications & Labeling
    Technical specifications and labeling (product parameters) of 1,2-difluoro-4- (trifluoromethyl) benzene
    There are currently 1,2-difluoro-4- (trifluoromethyl) benzene, and the technical specifications are related to the preparation method. When using pure raw materials, according to precise proportions, under suitable temperature and pressure conditions, it is prepared with a delicate reaction process. The reaction process must be strictly monitored to ensure that the reaction is complete and impurities are not present.
    As for the labeling, the product should be clearly labeled with the name "1,2-difluoro-4- (trifluoromethyl) benzene" and the key product parameters should be detailed. For example, the purity must be above [X]%, and the impurity content must be strictly controlled within [specific value]. In addition, physical properties such as color, smell, melting point, boiling point, etc. should also be clearly marked so that users can know their properties in detail and make good use of them. In this way, it is in line with technical specifications and labels to ensure the quality of the product.
    Preparation Method
    The preparation method of 1,2-difluoro-4- (trifluoromethyl) benzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
    To prepare this compound, suitable starting materials can be selected. Using fluoroaromatic hydrocarbon derivatives as substrates, the target product can be reached through a specific reaction path.
    In the production process, the reaction conditions need to be precisely regulated. Under a certain temperature and pressure, with the help of suitable catalysts, the reaction can be carried out in an orderly manner. For example, metal-catalyzed halogenated aromatic hydrocarbon fluorination can be used.
    The reaction step is very critical. First, the substrate interacts with the halogenated reagent, introducing halogen atoms, and then going through the fluorination step, replacing the halogen atoms with fluorine atoms. And it is necessary to pay attention to the sequence of the reaction and the progress of each step.
    In terms of catalytic mechanism, the catalyst can effectively reduce the activation energy of the reaction, improve the reaction rate and selectivity. The reasonable combination of metal catalyst and ligand can accurately guide the reaction direction and achieve the purpose of efficient preparation of 1,2-difluoro-4- (trifluoromethyl) benzene.
    Chemical Reactions & Modifications
    The chemical reaction and change of 1,2-difluoro-4- (trifluoromethyl) benzene can be studied. The chemical reaction is the change of the interaction of substances. In the reaction of 1,2-difluoro-4- (trifluoromethyl) benzene, or the disconnection of its bonds, the heavy distribution of atoms.
    In its reaction, fluorine groups and trifluoromethyl groups have characteristics. Fluorine has strong electronegativity and special molecular activity. Or it can respond to other substances in the way of nucleophilic and electrophilic.
    Want to change it, or change the temperature and pressure of the reaction, and adjust the amount of catalyst. When the temperature rises, the molecular energy increases, and the corresponding rate is increased; the pressure changes, or the shadow gas phase is reversed. Catalyst, can reduce the energy barrier of the response, promote its speed without changing its final state.
    After various investigations, we hope to obtain the wonderful reaction of 1,2-difluoro-4- (trifluoromethyl) benzene, so as to improve its properties and be the basis for all uses.
    Synonyms & Product Names
    1,2-Difluoro-4- (trifluoromethyl) benzene, also known as fluoro-trifluorotoluene, although its name is different, it refers to the same substance. In the course of my chemical research, this substance has attracted much attention. It has various nicknames, all of which show its characteristics and structure. Although the names are different, they are actually the same. This compound has a delicate structure and a large number of fluorine atoms. It is widely used in the field of organic synthesis. It is either a key raw material for the preparation of special materials, or an important intermediate in medicinal chemistry. All the different names are named by the academic community according to its characteristics and production methods. From this perspective, although the names are different, they all refer to this unique chemical substance, 1,2-difluoro-4- (trifluoromethyl) benzene. Its function in chemistry cannot be underestimated, and there may be more wonderful applications to be explored in the future.
    Safety & Operational Standards
    1,2-Difluoro-4- (trifluoromethyl) benzene is also a chemical product. In studying its safety and operating regulations, it is important and important.
    Looking at this substance, its properties are unique and different. Before using it, it is necessary to carefully observe its chemical and physical properties. In the storage area, it should be placed in a cool, dry and common place to avoid fire and heat, so as to prevent it from becoming dangerous. The reservoir must be strong and tight to prevent it from leaking and dangerous.
    As for the rules of operation, the operator must wear appropriate protective gear. Clothes to prevent corrosion, glasses to protect the eyes, and hands to cover the touch. The operation area should also be well-ventilated, so that the air is smooth and the risk is reduced. During use, do not approach fire and heat, and take precautions against shocks and collisions to prevent them from burning and exploding.
    If you are unlucky enough to vent, quickly leave the public in a safe place, and prohibit fire and electricity. The operator quickly puts on protective gear and collects the material in a suitable way. For small leaks, you can suck them up with sand or its lazy material, put them in a closed device, and then put them in a proper place. For large leaks, you should surround and control them, and report them to the special person quickly, and wait for them to be dealt with.
    All these are the safety and operation regulations for 1,2-difluoro-4- (trifluoromethyl) benzene. By following this rule, one can avoid danger, ensure safety, and protect the environment from goodness.
    Application Area
    Today there is a thing called 1,2-difluoro-4- (trifluoromethyl) benzene, which has wonderful uses in many fields. In the field of medicine, it can be used as a key intermediate to help create new medicines and cure various diseases. In the field of materials, it can add its characteristics to special materials and make them more suitable for needs.
    In the past, when there was no such thing, many things were difficult to do. Today, those who obtain it can develop new medicines and help those who are sick in the world; those who make materials can make strange materials, which can be used for utensils and fortifications, and facilitate people's livelihood. It is widely used, can make things smooth, and has extraordinary effects. It is an indispensable thing today, and it has made great contributions in the application fields of medicine and materials, benefiting the world and making our lives better.
    Research & Development
    In recent years, Yu dedicated himself to the research of 1,2-difluoro-4- (trifluoromethyl) benzene. This compound has unique properties and has great potential in many fields.
    At the beginning, I explored its synthesis method. After repeated experiments, I tried different raw material proportions and reaction conditions. In case of the dilemma of low reaction yield, or the problem of poor product purity. However, I did not give up, and devoted myself to studying, consulting ancient classics and current literature, and finally found an optimized method to improve the yield and purity.
    Its application is also studied. In the field of medicine, it can be used as a key intermediate to help the development of new drugs; in materials science, it can improve material properties. Looking to the future, we hope to use this as a foundation to expand its application scope, and work with colleagues to promote this compound to shine in more fields and realize its research and development ambitions.
    Toxicity Research
    Today, there is a thing named 1,2-difluoro-4- (trifluoromethyl) benzene, and our generation focuses on toxicity research. The properties of this thing are related to everyone's health and cannot be ignored.
    After detailed review, it has a special structure, and fluorine-containing groups are concentrated. Fluoride is active, which has a great impact on the toxicity of the thing. Or due to differences in structure, after it enters the body, it may interfere with the biochemical process.
    However, the current knowledge is still shallow, and many are unknown. In the context of experiments, it is important to observe its effect on organisms, or damage the ability of cells, and disrupt the order of metabolism. However, in order to obtain certainty, it is necessary to collect extensive data and investigate its rationale.
    The study of toxicity has a long way to go and is related to people's livelihood. We should make every effort to explore it in order to clarify its nature and protect everyone's well-being.
    Future Prospects
    Today there is a product named 1,2-difluoro-4- (trifluoromethyl) benzene. We are researchers of chemicals, and we look forward to the future of this product.
    This material is unique, or it can shine in the field of medicine. Its exquisite structure may be the basis for creating special drugs, helping physicians overcome difficult diseases and save patients from pain.
    In the field of materials, it is also expected to develop its capabilities. Or make the material have extraordinary properties, such as stronger stability and specific conductivity, which will open up a new path for the development of high-tech materials.
    Although there may be thorns in the road ahead, we uphold the heart of research and make unremitting exploration. Looking forward to the future, we must make the best use of it to bring well-being to the world and live up to our expectations for the future, so that this material can bloom brilliantly and promote the progress of the world in various fields.
    Where to Buy 1,2-Difluoro-4-(Trifluoromethyl)Benzene in China?
    As a trusted 1,2-Difluoro-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,2-Difluoro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,2-difluoro-4- (trifluoromethyl) benzene?
    1% 2C2-diene-4- (trienomethyl) naphthalene is an organic compound that has important uses in many fields.
    In the field of organic synthesis, it is often used as a key intermediate. With its unique chemical structure, it can derive many organic compounds with complex structures and specific functions through various chemical reactions. For example, through electrophilic substitution reactions, various functional groups can be introduced at specific positions in the naphthalene ring to lay the foundation for the synthesis of specific biologically active drug molecules; or through cyclization reactions with alkenyne compounds, novel polycyclic compounds can be constructed, providing key raw materials for the development of new materials.
    In the field of materials science, 1% 2C2-diene-4- (trienomethyl) naphthalene also performs well. Due to its conjugated structure giving good photoelectric properties, it can be applied to the preparation of optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells. In OLEDs, it may act as a luminescent material, with unique molecular structure and energy level characteristics, to achieve high-efficiency luminescence, improve device luminescence efficiency and color purity; in organic solar cells, it may be used as an electron donor or receptor material to enhance the absorption of sunlight and charge transport efficiency, thereby improving the photoelectric conversion efficiency of batteries.
    In the field of medicinal chemistry, this compound also shows potential value. Studies have found that some compounds containing naphthalene rings and alkenyl structures have certain biological activities. 1% 2C2-diene-4- (trienomethyl) naphthalene may act on specific biological targets due to its structural characteristics, and has potential biological activities such as anti-inflammatory and anti-tumor. It provides important lead compounds for the development of new drugs. Scientists can modify and optimize its structure to develop high-efficiency and low-toxicity innovative drugs.
    In summary, 1% 2C2-diene-4- (trienomethyl) naphthalene has a wide range of uses in organic synthesis, materials science and medicinal chemistry. With in-depth research, it is expected to emerge in more fields and contribute to scientific development and technological progress.
    What are the physical properties of 1,2-difluoro-4- (trifluoromethyl) benzene?
    1% 2C2-diene-4- (trienyl methyl) naphthalene is a kind of organic compound. The physical properties of this substance are particularly important, which is related to its application in many fields.
    First of all, its properties are at room temperature and pressure, or in the appearance of a solid state. This is due to the force between molecules, resulting in a relatively stable structure. Looking at its color, it may be white to light yellow powder, like fine frost and snow, delicate and uniform.
    Times and melting point, after various experiments, its melting point is in a specific temperature range. Due to the degree of orderly arrangement of molecules and the strength of interactions, the melting point is determined. The definition of this temperature range provides an important basis for its purification and identification.
    Furthermore, when it comes to the boiling point, although it is not easy to reach the boiling point under normal conditions, the characteristics of the boiling point are highlighted in a specific high pressure environment and when the temperature rises. The value of the boiling point is also affected by the intermolecular forces and the relative molecular mass.
    In terms of solubility, it may have a certain solubility in common organic solvents such as ethanol and ether. This is because of the principle of "similar miscibility", the compatibility of molecular polarities determines whether it can be dissolved in it. In water, because of the characteristics of the molecular structure, the solubility may be quite limited.
    In addition, density is also one of its physical properties. The size of the density is related to its fluctuation in different media, and it is of great significance in chemical separation and preparation scenarios.
    The physical properties of 1% 2C2-diene-4- (trienyl methyl) naphthalene, such as properties, melting point, boiling point, solubility, density, etc., are all related and have their own uses. They are all key elements in research and application in many fields such as organic synthesis and materials science.
    Is the chemical properties of 1,2-difluoro-4- (trifluoromethyl) benzene stable?
    1% 2C2-diene-4- (trienomethyl) naphthalene This compound has a complex structure and contains multiple unsaturated bonds and specific substituents. Whether its chemical properties are stable needs to be considered from many aspects.
    From the perspective of chemical bonds, the carbon-carbon double bonds and aromatic ring structures in molecules have a great influence on its properties. Carbon-carbon double bonds have high reactivity and are prone to addition reactions. For example, when reacting with electrophilic reagents such as halogens and hydrogen halides, they are vulnerable to electrophilic reagents due to exposure to π electron clouds. Although aromatic rings have certain stability and are aromatic according to the Hocker rule, the side chain substituents will change their electron cloud distribution, making some positions of aromatic rings more prone to electrophilic substitution reactions.
    From the spatial structure analysis, the position and size of the substituents will affect the intermolecular forces and the accessibility of the reaction check point. If the substituents generate steric resistance, it will hinder some reactions, which will affect the stability. For example, a large volume of substituents may prevent the reagent from approaching the reaction check point, reduce the reactivity, and increase the stability to a certain extent; conversely, if the substituents are conducive to intermolecular interactions, such as the formation of hydrogen bonds or π-π stacking, it will also affect its stability and reactivity.
    Overall, 1% 2C2-diene-4- (trienyl methyl) naphthalene is not a chemically stable compound due to its unsaturated bonds, and it is prone to various reactions under suitable conditions to change its chemical structure.
    What is the production method of 1,2-difluoro-4- (trifluoromethyl) benzene?
    The preparation of 1% 2C2-diene-4- (trienomethyl) benzene is a delicate chemical process. To make this substance, the following steps can be used.
    First take a suitable benzene raw material, select its pure and rare impurities as the starting base. The benzene raw material should have good chemical stability and reactivity before it can proceed smoothly in the subsequent reaction.
    Next, the alkenyl group needs to be introduced. The introduction of the alkenyl group can be achieved by a specific chemical reaction. For example, the nucleophilic substitution reaction of halogenated olefins and benzene under specific catalysts and reaction conditions is carried out. The choice of this catalyst is very critical. The agent with moderate activity and good selectivity, such as some transition metal complex catalysts, can make the reaction proceed efficiently in the desired direction and introduce alkenyl groups precisely. And the reaction conditions also need to be carefully controlled. Temperature, pressure, reaction time, etc. are all factors that affect the reaction effect. If the temperature is too low, the reaction rate will be slow, and if it is too high, side reactions may breed, so it should be maintained at a suitable temperature range, about [X] to [X] degrees Celsius. The pressure should also be moderate, about [X] atmospheric pressure, and the reaction time should be [X] hours to ensure that the alkenyl group can be stably and accurately attached to the benzene ring.
    After the alkenyl group is successfully introduced, the methylation modification is carried out for a specific position. This methylation step can be completed by using methylating reagents in an appropriate reaction environment. Similarly, this process also needs to be carefully regulated for many reaction factors. The activity and selectivity of the methylating reagents used must meet the requirements of the reaction. For example, when choosing common methylating reagents such as iodomethane, suitable bases should be used to promote the reaction. The pH and temperature of the reaction environment also need to be carefully considered to achieve the best methylation effect, so that the methyl groups fall precisely at the specific position of the triene, and finally become 1% 2C2-diene-4- (trienomethyl) benzene. Throughout the preparation process, each step requires fine operation and rigorous control to achieve the desired product.
    What are the precautions for storing and transporting 1,2-difluoro-4- (trifluoromethyl) benzene?
    1% 2C2-diene-4- (trienomethyl) naphthalene is very special, and various precautions are essential during storage and transportation.
    The first thing to pay attention to is the control of temperature. This material may change due to temperature fluctuations. Under high temperature, it may cause chemical reactions or even the risk of decomposition. Therefore, it should be stored in a cool place to keep the temperature constant within a suitable range. Do not expose it to direct sunlight or high temperature environment.
    The second is the prevention of humidity. Moisture is easy to interact with this substance, or its quality may be damaged. The storage place must be kept dry, and desiccant can be placed next to it to absorb excess water vapor and avoid moisture and deterioration.
    Furthermore, the packaging also needs to be rigorous. The packaging material used should have good sealing properties, which can effectively isolate air and moisture, and the material must have no chemical reaction with the substance to prevent material leakage due to package damage.
    When transporting, stable transportation is essential. Avoid severe bumps and collisions during driving, otherwise the packaging may be damaged and cause danger. And the environment in the transportation vehicle should also be in line with the storage conditions, and keep its temperature and humidity appropriate.
    In addition, clear identification is indispensable. On the storage container and transportation vehicle, the name, characteristics and precautions of the substance should be clearly marked, so that relevant personnel can understand its risks and operate properly. In case of leakage and other emergencies, we must follow the established emergency measures to ensure safety. In this way, we must ensure that 1% 2C2-diene-4- (trienomethyl) naphthalene is safe during storage and transportation.