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1,2-Difluoro-4-Methylsulfonylbenzene

1,2-Difluoro-4-Methylsulfonylbenzene

Hongda Chemical

Specifications

HS Code

433052

Chemical Formula C7H6F2O2S
Molar Mass 194.183 g/mol
Appearance Typically a solid (description may vary based on purity and conditions)
Solubility In Water Expected to be low (due to non - polar aromatic and fluorine groups with a relatively small polar sulfonyl group)
Solubility In Organic Solvents Likely soluble in common organic solvents like dichloromethane, chloroform (due to its organic nature)
Vapor Pressure Low (as it is likely a solid at room temperature and has relatively high molecular weight)

As an accredited 1,2-Difluoro-4-Methylsulfonylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2 - difluoro - 4 - methylsulfonylbenzene: Packed in 1 - kg bottles for chemical storage.
Storage 1,2 - difluoro - 4 - methylsulfonylbenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container to prevent vapor leakage. Due to its chemical nature, it should be separated from incompatible substances to avoid potential reactions. Ensure the storage area has appropriate spill - containment measures.
Shipping 1,2 - difluoro - 4 - methylsulfonylbenzene is shipped in sealed, corrosion - resistant containers. It's handled with care, following strict regulations for chemical transportation to ensure safety during transit.
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1,2-Difluoro-4-Methylsulfonylbenzene 1,2-Difluoro-4-Methylsulfonylbenzene
General Information
Historical Development
Taste the industry of chemistry, study all kinds of things, and change with each passing day. Today there is 1,2-difluoro-4-methylsulfonylbenzene, which was not paid much attention by the academic community at first. However, as time went by, researchers continued to explore. I began to try it with a simple method, but the results were not obvious. Later, I gathered the wisdom of everyone, changed my course, and considered the reaction conditions and the ratio of raw materials in detail. After several years, a good method was obtained, the yield gradually increased, and the quality was also excellent. As a result, this product has emerged in the fields of medicine and materials, and its use is becoming more and more widespread. Looking at the course of its development, it is like a boat on the sea. Although it has gone through twists and turns, with the perseverance of the dukes, it has finally reached the other side, adding to the temple of chemistry and paving the way for future research.
Product Overview
Today there is a substance called 1,2-difluoro-4-methylsulfonylbenzene. Its shape or crystalline state, pure in color and uniform in quality. The preparation of this substance requires several reactions, and its steps, temperature, and material ratio can be controlled by fine methods.
Its properties are stable, and it is rarely phased with other substances under normal conditions. However, when it comes to strong heat and strong oxidation agents, it has a different change. In the field of organic synthesis, this product has a wide range of uses and can be used as a key intermediate, paving the way for the synthesis of many complex compounds. With its fluorine-containing and sulfonyl structure, the product is endowed with unique properties, or its stability is increased, or its activity is changed, so that the synthesized substance has specific properties, which can be used in many aspects such as medicine and materials.
Physical & Chemical Properties
1,2-Difluoro-4-methylsulfonylbenzene has special properties between matter and chemical. Its shape is solid, stable at room temperature, and then changes when heated or exposed to other agents. Looking at it, the color is transparent but the taste is light, and it can be soluble in various agents, such as alcohols and ethers. Regarding its melting and boiling, there is a fixed number. It melts at XX degrees and boils at XX degrees, which is caused by its intermolecular force.
In terms of chemical properties, the sulfonyl group and the fluorine atom give it life. The electricity of fluorine is negative, so that the electron cloud of the benzene ring is changed, and it is easy to get electrophilic. Methylsulfonyl is also an active site, which can react with many substances and form a new chemical structure. It is widely used in fields such as pharmaceutical research and material production. It is important for chemists to explore its properties and expand its use. It is expected to contribute to the development of industry and science.
Technical Specifications & Labeling
Technical specifications and labels for 1,2-difluoro-4-methylsulfonylbenzene (commodity parameters)
There is a product named 1,2-difluoro-4-methylsulfonylbenzene. The technical specifications are related to the preparation method and need to follow a specific process. The selection of raw materials, when carefully selected, must be accurate in proportion. The reaction conditions, temperature, pressure, etc. are all fixed, and a slight deviation may cause a change in quality.
As for the logo, the product parameters are clearly marked. In terms of appearance, it should have a specific color and state, and there should be no variegated colors or foreign objects. Purity is a high standard, and the impurity content needs to be strictly controlled. Other parameters such as molecular weight, melting point, boiling point, etc., also need to be accurately marked to clarify their characteristics. In this way, it can meet the technical specifications and labels of this product, and can provide users with accurate information to suit various needs.
Preparation Method
The method of preparing 1,2-difluoro-4-methylsulfonylbenzene involves raw materials and production processes, reaction steps and catalytic mechanisms. First, take an appropriate amount of raw materials, such as fluorine-containing compounds, methylsulfonyl-related reagents, etc., and match them in precise proportions. In the reactor, control the appropriate temperature and pressure to make it react. The first step is to promote the combination of fluorine-containing groups and benzene rings. This step requires a specific catalyst to increase the reaction rate, and the catalyst is strictly selected, because different catalysts have a great impact on the selectivity and efficiency of the reaction. Second, introduce methylsulfonyl groups to precisely control the reaction conditions, such as reaction time, pH, etc. Pure 1,2-difluoro-4-methylsulfonylbenzene is obtained by separation and purification. The whole process, the proportion of raw materials, reaction conditions and catalytic mechanism are all key to the purity and yield of the product.
Chemical Reactions & Modifications
Today there is a substance called 1,2-difluoro-4-methylsulfonylbenzene. In the way of chemical research, its reaction and modification are the top priority.
Looking at this substance, in order to understand its reaction, it is necessary to explore its molecular structure and characteristics. The positions of fluorine and methylsulfonyl in this molecule have a profound impact on its reaction. Fluorine has strong electronegativity, which changes the density of the electron cloud at the ortho position, and causes nucleophilic and electrophilic reactions. Methylsulfonyl groups also have unique effects, either increasing molecular stability or changing reactivity.
As for the way of modification, new groups can be introduced through substitution reactions to adjust their physicochemical properties. Or change its solubility, or change its reactivity, in order to be suitable for various uses. It can also use addition, elimination and other reactions to expand its molecular structure and produce new compounds.
All of these are what chemical researchers should study in the reaction and modification of 1,2-difluoro-4-methylsulfonylbenzene.
Synonyms & Product Names
In modern times, there is a thing named 1,2 - Difluoro - 4 - Methylsulfonylbenzene. This thing has a wide range of uses in the chemical industry, but its name is complicated and difficult to know. Therefore, the industry often uses the name of the synonym and the name of the product, so that it can be used.
Looking at the ancient world of Fu, all kinds of utensils have different names to meet the needs of all parties. Today, this chemical thing also follows this example. Its synonymous name, either by its nature or by its construction, is designed to achieve the effect of precise expression. And the name of the product is mostly created by the merchant, who wants to show its difference and attract the attention of the public.
Such as 1,2 - Difluoro - 4 - Methylsulfonylbenzene, the name of the synonym or its chemical structure, in order to simplify its constituent elements, so that those who know its essence. Trade names are ingenious, or take auspicious meaning, or its unique function, so that it stands out in the market. This is all for the use of its spread, convenience, and prosperity in the chemical industry, which is of great benefit.
Safety & Operational Standards
Safety and Operation Specifications for 1,2-Difluoro-4-methylsulfonylbenzene
The 1,2-difluoro-4-methylsulfonylbenzene is an important substance in chemical research. To investigate its safety and operation specifications, do not be careless.
#1. Storage Regulations
This substance should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Cover its properties or be unstable due to changes in temperature and humidity, so the storage place should be carefully selected. The container should also be well sealed to avoid contact with air, moisture, etc. to cause deterioration.
#Second, the method of use
When taking 1,2-difluoro-4-methylsulfonylbenzene, be cautious. Wash your hands first, wear clean protective clothing, and wear appropriate gloves and goggles. The tools for use also need to be clean and dry to prevent impurities from mixing in. When measuring, be precise according to the needs of the experiment, and do not increase or decrease at will, so as not to affect the accuracy of the experiment.
#3. The essentials of operation
During the operation, the experimental environment must be well ventilated. If there are operations such as heating, pay more attention to the heat, slowly heat up, and closely observe the changes of the substance. Do not mix the substance with incompatible substances to prevent violent reactions. After the operation is completed, all utensils used should be cleaned up in time, and the remaining substances should be properly stored.
#4. Emergency measures
If you accidentally come into contact with this substance and touch the skin, rinse it with a large amount of flowing water as soon as possible; if it enters the eye, rinse it with flowing water or normal saline immediately, and seek medical attention as soon as possible. In the event of a leak, personnel from the contaminated area should be quickly evacuated to a safe place and isolated. In the event of a small leak, it should be absorbed with inert materials such as sand and vermiculite; in the case of a large leak, it is necessary to build a dike or dig a pit for containment, transfer it to a tanker or a special collector with a pump, and recycle it or transport it to
All research operations involving 1,2-difluoro-4-methylsulfonylbenzene should strictly abide by the above safety and operation specifications to ensure the smooth operation of the experiment and the safety of personnel.
Application Area
1,2-Difluoro-4-methylsulfonylbenzene, this chemical has a wide range of application fields. In medical medicine, it can be used as a key raw material for drug synthesis. Because of its special chemical structure, it can help pharmaceutical manufacturers accurately construct drug molecules to achieve the effect of treating various diseases.
In the field of materials science, it also plays an important role. It can be used to create polymer materials with special properties, such as enhancing the stability and weather resistance of materials. Because of its unique chemical properties, it can be cleverly combined with other substances to greatly improve the properties of materials.
In the fine chemical industry, it is often the starting material for the synthesis of special chemicals. With its structural characteristics, it can generate a variety of high-value-added products, driving the development of the fine chemical industry. It is actually widely used and has promising prospects.
Research & Development
Today, there is a product named 1,2-difluoro-4-methylsulfonylbenzene. Our generation is a chemical researcher to explore its research and progress.
This substance has unique properties and may have potential uses in the fields of chemical industry and medicine. We have carefully observed its structure, and we know the wonder of its molecules. The position of fluorine and methyl sulfonyl groups gives it specific activity.
Study its synthesis method, optimize the path, and seek high-efficiency and low-consumption techniques. After repeated trials, improve the process, hope to increase its yield and reduce its cost.
Looking to the future, I hope this substance will shine in the research and development of new materials and drug creation. We should persevere, study unremitting, and promote its transformation from research to use, so as to advance science and thrive in industry.
Toxicity Research
If you taste the things in the world that are harmful to the people, you must not ignore them. Today, there is a thing named 1,2 - Difluoro - 4 - Methylsulfonylbenzene. In the field of our chemical research, its toxicity research cannot be ignored.
Observe this thing, although it has the value of chemical research, the discussion of toxicity is related to all living beings. If the toxicity is unknown, it may cause harm to people when it is applied. Therefore, it is necessary to observe its impact on the human body and the environment in detail.
When using scientific methods and rigorous states, explore its toxicity. Observe its contact route, inhalation, ingestion, skin contact, what are the harms. Also observe its long-term and short-term effects, metabolism in organisms, and impact on ecology.
It is hoped that through in-depth toxicity research, the advantages and disadvantages will be clarified, so that this substance can be used by human beings under reasonable control, and its harm can be avoided, so as to ensure the well-being of all people and the harmony of the ecology.
Future Prospects
1,2 - Difluoro - 4 - Methylsulfonylbenzene, it is also a matter of transformation. We can look forward to the development of this kind of material, or it can be used in many domains. The way of cultivation, or can help research new materials, so as to solve the diseases of the world; the field of materials, or can make special materials, it is like a need.
Those of us who are scientific researchers must exhaust our efforts and explore deeply. With the aim of intensive research, understanding its secrets, and making good use of it. Make this kind of thing, before it is widely used, and use it for the benefit of the world, so as to become the macro of our scientific research. This is our unseen prospect.
Where to Buy 1,2-Difluoro-4-Methylsulfonylbenzene in China?
As a trusted 1,2-Difluoro-4-Methylsulfonylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Difluoro-4-Methylsulfonylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-difluoro-4-methylsulfonylbenzene?
1% 2C2-diene-4-methylbenzaldehyde, which has important uses in many fields. In the field of pharmaceutical synthesis, it is often used as a key intermediate. For example, when preparing some antibacterial drugs, it can take advantage of its unique chemical structure and participate in the construction of drug molecules through a series of reactions, helping to synthesize compounds that have strong inhibitory effects on specific bacteria, broadening the path for pharmaceutical research and development.
In the fragrance preparation industry, 1% 2C2-diene-4-methylbenzaldehyde can impart a unique flavor to fragrances due to its special aroma. Or it can be cleverly matched with other fragrance ingredients to create a rich and unique fragrance, which is widely used in perfumes, air fresheners and other products to enhance its aroma quality and uniqueness.
In the field of materials science, it also has its place. It can participate in the synthesis of specific polymers or functional materials. With its active groups, it can react with other monomers to give materials special physical or chemical properties, such as improving the optical properties of materials and enhancing the stability of materials, etc., promoting innovation and development in the field of materials science.
In summary, 1% 2C2-diene-4-methylbenzaldehyde plays an important role in many fields such as medicine, fragrances, materials, etc., and is of great significance to the development of related industries.
What are the physical properties of 1,2-difluoro-4-methylsulfonylbenzene?
1% 2C2-diene-4-methyl-3-pentenonitrile, this is an organic compound. Its physical properties are as follows:
Viewed at room temperature and pressure, or a colorless to light yellow liquid, clear and translucent, without impurities visible to the naked eye.
Smell, or have a special pungent odor, this odor may be caused by the characteristics of nitrile groups and unsaturated bonds in the molecular structure. Such odors can be used as a basis for identifying the substance to a certain extent, but because of their irritation, special care should be taken when smelling to avoid harming the respiratory tract.
When it comes to boiling points, due to the presence of conjugated dienes and nitrile groups in molecules, the intermolecular forces are more complex, resulting in boiling points in a specific range. Specifically, about a certain temperature value (because the exact value is affected by many experimental conditions, it is difficult to give the exact value here). This boiling point characteristic makes it possible to achieve by distillation and other means according to the difference in boiling points during separation and purification.
Its melting point also has a certain value due to structural characteristics. The regularity of molecules and the action force work together to determine the melting point range. This property is of great significance for the storage and use of substances and solid states.
As for the density, it may be different from water. In general, due to its molecular composition and structural characteristics, the density may be slightly greater than that of water, so when mixed with water, it will sink to the bottom. This density characteristic plays an important role in operations such as phase separation.
In terms of solubility, in view of the properties of its organic compounds, it may have good solubility in organic solvents such as ethanol, ether, acetone, etc. Due to the principle of "similar phase solubility", its molecules and organic solvent molecules can form a certain force to promote dissolution. However, in water, the solubility is poor, because there are differences in the polarity of molecules and water molecules, it is difficult to form effective interactions with water.
Is the chemical properties of 1,2-difluoro-4-methylsulfonylbenzene stable?
The chemical stability of 1% 2C2-diene-4-methyl-3-nitrobenzoylbenzene depends on many chemical principles and actual conditions. Let me explain in detail.
From a structural point of view, the compound contains carbon-carbon double bonds, methyl groups, nitro groups and other groups. The carbon-carbon double bonds have high reactivity. Due to the exposure of the π bond electron cloud, it is vulnerable to the attack of electrophilic reagents and an addition reaction occurs. For example, with the addition of hydrogen halide, the electron cloud density at the double bond is high, and the positively charged part of the hydrogen halide is easy to combine with it, thereby changing the molecular structure, which has an impact on the stability of the compound.
methyl group is the power supply, which can affect the electron cloud distribution of benzene ring through induction effect, so that the electron cloud density of benzene ring ortho-para is increased, and the electrophilic substitution reaction is more likely to occur, which may cause the compound to change under specific conditions and affect the stability.
Nitro group is a strong electron-absorbing group, which reduces the electron cloud density of benzene ring, especially the ortho-para is obviously reduced. Although the electrophilic substitution activity of benzene ring is reduced, it changes the molecular charge distribution, enhances the molecular polarity, or affects its stability in different solvents, and the nitro group is oxidizing. Under appropriate conditions, it can participate in the redox reaction and change the structure of the compound.
In addition, the compound contains multiple groups, and each group affects each other, such as conjugation effect, steric The conjugation effect may reduce the molecular energy and enhance the stability; when the steric resistance is large, the groups repel each other, affecting the molecular configuration and also having an effect on the stability.
In summary, the chemical properties of 1% 2C2-diene-4-methyl-3-nitrobenzoylbenzene are not stable. Under different conditions, each group may participate in a variety of reactions, resulting in structural changes of the compound. Its stability requires comprehensive consideration of specific reaction conditions and environmental factors.
What are the synthesis methods of 1,2-difluoro-4-methylsulfonylbenzene?
1% 2C2-diene-4-methyl-6-nitro-benzaldehyde. To synthesize this product, the following ancient method can be used:
First, m-toluidine is used as the starting material, and the diazonium salt is obtained by diazotization. The specific operation is: dissolve m-toluidine in dilute acid, cool it down, slowly add sodium nitrite solution dropwise, keep it low temperature, and make the diazotization complete. This step requires careful temperature control to prevent the decomposition of diazonium salts.
Then, the diazonium salt reacts with the cuprous salt, and a Sandmeier reaction occurs, introducing halogen atoms to form halogenated aromatics. During the reaction, a suitable cuprous salt, such as cuprous chloride or cuprous bromide, should be selected, depending on the desired halogen atom.
Next, the halogenated aromatic hydrocarbon is nitrified. Concentrated sulfuric acid and concentrated nitric acid are mixed to form a mixed acid, and halogenated aromatic hydrocarbons are slowly added. The reaction temperature and time are controlled, so that nitro groups are precisely introduced into specific positions to obtain aromatic hydrocarbon derivatives containing nitro and halogen atoms. This step is dangerous, the mixed acid is highly corrosive, and the operation must be cautious.
After that, use the Grignard reagent to react to form a carbon-carbon bond. The Grignard reagent for halogenated hydrocarbons is first prepared. The halogenated hydrocarbons are dissolved in anhydrous ether or tetrahydrofuran After that, the Grignard reagent is reacted with a suitable carbonyl compound and hydrolyzed to obtain an alcohol containing the target carbon chain.
Finally, the alcohol is oxidized to oxidize the alcohol to an aldehyde with a suitable oxidant, such as chromic acid or manganese dioxide, to obtain 1% 2C2-diene-4-methyl-6-nitro-benzaldehyde. The oxidation process requires the selection of the right oxidant and reaction conditions to ensure moderate oxidation and no excessive oxidation to carboxylic acids. The entire synthesis process is complicated, and the reaction conditions at each step need to be strictly controlled to obtain high-purity products.
What are the precautions for storing and transporting 1,2-difluoro-4-methylsulfonylbenzene?
1% 2C2-diene-4-methylthiazolinone This material needs to be paid attention to many key things during storage and transportation.
The first thing to pay attention to is the characteristics of its chemical properties. 1% 2C2-diene-4-methylthiazolinone has a certain chemical activity, and it is easy to react when encountering specific substances. In case of strong oxidants, or causing violent chemical reactions, there is a risk of combustion or even explosion. Therefore, when storing, it must be strictly isolated from oxidant substances, stored in separate warehouses, and must not be mixed in one place. During transportation, it is also necessary to ensure that this substance is not transported with oxidant cargo to prevent accidents.
Check its stability again. The substance is not stable under certain conditions, and changes in temperature and humidity may affect it. In high temperature environments, it may accelerate its decomposition or deterioration. When storing, a cool and dry place should be selected, and the temperature should be controlled within a suitable range, generally 5 ° C - 25 ° C. When transporting, if it is hot weather, effective cooling measures should be taken, such as the use of refrigerated transportation equipment to ensure that it is in a stable state.
Furthermore, this substance may have certain toxicity and irritation. The storage place should be well ventilated to prevent volatile gas from accumulating indoors and endangering people's health. When transporting, relevant operators must be equipped with complete protective equipment, such as gas masks, protective gloves, protective clothing, etc., to avoid direct contact. In the event of a leak, quickly evacuate the surrounding personnel and isolate the contaminated area. Emergency responders need to wear professional protective equipment to clean up to prevent the leakage from spreading and causing greater harm.
Packaging is also crucial. The packaging used for storage and transportation must be strong and well sealed, which can effectively resist the erosion of external factors and prevent leakage. The packaging material should be compatible with the substance and do not react with it. Regularly check the packaging. If there is any damage or aging, replace it in time to ensure the safety of storage and transportation.