Hongda Chemical
Products
Home  /  Products  / 

1,2-Difluoro-4-(Methylsulfonyl)Benzene

1,2-Difluoro-4-(Methylsulfonyl)Benzene

Hongda Chemical

Specifications

HS Code

901844

Chemical Formula C7H6F2O2S
Molar Mass 192.183 g/mol
Appearance Solid (predicted)
Boiling Point Estimated around 300 - 350 °C
Melting Point 110 - 114 °C
Density Estimated around 1.4 - 1.6 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Very low at room temperature
Pka No acidic hydrogens (no relevant pKa value)

As an accredited 1,2-Difluoro-4-(Methylsulfonyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2 - difluoro - 4 - (methylsulfonyl)benzene packaged in 100 - gram vials.
Storage 1,2 - difluoro - 4 - (methylsulfonyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of a material resistant to chemical corrosion, like glass or some specialized plastics, to prevent leakage and maintain its chemical integrity.
Shipping 1,2 - difluoro - 4 - (methylsulfonyl)benzene is shipped in sealed, corrosion - resistant containers. Adequate cushioning is used to prevent damage. It's transported following strict chemical shipping regulations to ensure safety during transit.
Free Quote

Competitive 1,2-Difluoro-4-(Methylsulfonyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1,2-Difluoro-4-(Methylsulfonyl)Benzene 1,2-Difluoro-4-(Methylsulfonyl)Benzene
General Information
Historical Development
1,2-Difluoro-4- (methylsulfonyl) benzene is also a chemical product. At the beginning, the researchers were in the field of chemical, diligently exploring the unknown. At the beginning, the properties and systems of this thing were not well known. However, with the progress of research, various sages gradually obtained the method of making this thing in practice. Begin with a rough and simple method, and then chase after the good, so that the yield gradually increases and the quality is better. In the meantime, all the sages thought hard, observed the matching of raw materials, observed the environment of the reaction, and sought the best way. After years, from ignorance to mastery, the cognition and production of 1,2-difluoro-4- (methyl sulfonyl) benzene have made great progress, which is the work of chemical researchers over the years.
Product Overview
1,2-Difluoro-4- (methylsulfonyl) benzene is a chemical substance that I have recently studied. This substance is colorless to slightly yellow and has unique physical and chemical properties. Its melting point and boiling point have been accurately determined, and it has specific solubility in specific solvents.
Structurally, the ingenious substitution of fluorine atoms and methylsulfonyl groups on the benzene ring gives it special chemical activity. After many experiments, it has been observed that its chemical behavior under various reaction conditions, such as nucleophilic substitution, oxidation and reduction, all of which show unique characteristics.
This substance may have potential applications in materials science, drug development and other fields. I will continue to conduct in-depth research in order to clarify more of its properties and uses, so as to contribute to the development of chemistry and help it play an important role in practical applications.
Physical & Chemical Properties
1,2-Difluoro-4- (methylsulfonyl) benzene, this substance has unique physical and chemical properties. Its appearance may be colorless to slightly yellow crystals, which are relatively stable at room temperature. The melting point is about [X] ° C, and the boiling point is about [X] ° C, which determines its phase change.
From the perspective of chemical properties, it is chemically active due to its fluorine and methylsulfonyl groups. Fluorine atoms have high electronegativity, causing molecules to have polarity, which affects their solubility. It has a certain solubility in some organic solvents such as ethanol and acetone, but low solubility in water. The presence of methyl sulfonyl groups allows the substance to participate in a variety of organic reactions, such as nucleophilic substitution reactions, and is an important intermediate in organic synthesis. It may have potential application value in the fields of medicinal chemistry and materials science.
Technical Specifications & Labeling
Nowadays, there is a product called 1,2-difluoro-4- (methylsulfonyl) benzene, which is very important in the field of chemical research. Its process specifications and identification (product parameters) are related to the quality and application of this substance.
Regarding its process specifications, the method of preparation needs to be specified, the raw materials must be pure, and the steps should be careful. The temperature and time of the reaction are fixed, so that high-quality products can be obtained.
As for the identification (product parameters), the details of the ingredients, the purity geometry, and the number of impurities should be clear. These parameters, such as the beacon on the boat, help the user to know its nature and make good use of it. Strictly adhere to the process specifications and accurately establish the identification (product parameters), so that this chemical can perform its functions in the fields of scientific research and production without error.
Preparation Method
The method of preparing 1,2-difluoro-4- (methylsulfonyl) benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be selected with high purity, such as difluorobenzene and reagents containing methylsulfonyl groups. The first condition of the reaction step is controlled, and the two are blended in a precise ratio at a specific temperature and pressure. The catalytic mechanism is also crucial, and a high-efficiency catalyst can be selected to promote the reaction rate and increase the purity of the product. Among them, the adjustment of temperature is related to the urgency of the reaction process; the control of pressure affects the activity of the substance. And the operation process needs to be in accordance with specifications and fine and minute, in order to obtain high-quality 1,2-difluoro-4- (methylsulfonyl) benzene products, which can be used in the chemical industry.
Chemical Reactions & Modifications
I tried to study 1,2 - Difluoro - 4 - (Methylsulfonyl) Benzene. It took a lot of thought to change the reaction. At the beginning, the reaction path was not smooth, the yield was flat, and the obtained product was difficult to call good.
I thought deeply about its rationale, observed the conditions of change, and studied the nature of matter. Thinking ancient people said: "If you are poor, you will change, and if you change it, you will be flexible." Then you change the temperature of the response, adjust the amount of the agent, and change the method of response.
Not long after, the fruit will be improved. The yield gradually rises, and the quality of the product is also excellent. This is the test of change, but also the experience of common. The science of chemical response is not static, and it needs to change according to things, times, and circumstances. Only those who can be fickle can master the wonders of transformation and obtain the quality they seek. Looking at the changes in material reactions, we can see that the way to transformation and adaptation lies in not following the rules and having the courage to seek changes, so as to obtain the positive results of transformation and improvement.
Synonyms & Product Names
1,2-Difluoro-4- (methylsulfonyl) benzene, which has attracted more and more attention in today's chemical research. Its synonyms and trade names are also studied in detail by our generation.
Looking at the evolution of past chemistry, the names of substances vary depending on the order, characteristics or origin of discovery. 1,2-Difluoro-4- (methylsulfonyl) benzene, or those named according to its structural characteristics, because it contains difluoro atoms and methylsulfonyl groups on the benzene ring, so it has a nickname similar to "fluorosulfonbenzene". Although it is abbreviated, it can also express its general structure.
As for the trade name, the merchant may name it according to its use and performance. In the field of material synthesis, if it can be used as a high-efficiency intermediate, or given a name such as "excellent sulfonated fluorobenzene", it will be valued by the industry and widely used in various chemical processes to promote the progress of the chemical industry.
Safety & Operational Standards
1,2-Difluoro-4- (methylsulfonyl) benzene, this chemical substance is related to safety and operation standards, and it is what our chemical researchers should carefully study.
Husband safety matters, the first protection. When handling this object, it is necessary to wear suitable protective equipment. Such as special protective clothing, it can control its quality and skin contact, and protect the skin from invasion; goggles must be clear and firm to prevent it from splashing into the eyes and damaging the eyes. Masks are also indispensable. Choose those with excellent filtration effect to block their qi from breathing and keep the lungs healthy.
Furthermore, the place of operation must be well ventilated. Set up a strong ventilation device, so that the air in the room is always fresh, and harmful air cannot accumulate. And the place where the goods are placed should be dry and cool, protected from heat and open flames, to prevent unexpected changes.
As for the operation specifications, when weighing, the utensils must be accurate. The calibration of the scale should not be ignored, so that the quantity value is correct. When dissolving, choose the appropriate solvent according to its nature, and stir it moderately to promote its dissolution without other changes. The reaction process, when strictly observed, temperature control and control, are all key. Heating and cooling, according to the rules, cannot be done carelessly.
If you are careless, touch this thing and rinse it with a lot of water quickly. Those who enter the eyes should seek medical attention immediately after flushing; those who are stained with clothes should take off and cleanse themselves quickly.
All these are the essentials of the safety and operation of 1,2-difluoro-4- (methylsulfonyl) benzene. Our researchers should keep in mind and practice to ensure that everything goes smoothly and is safe.
Application Area
1,2-Difluoro-4- (methylsulfonyl) benzene, this chemical substance, its application field is very critical. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create novel and special drugs to treat various diseases and add a weapon for doctors to eliminate diseases. In the field of material science, it also has important uses. It can optimize the characteristics of materials, such as improving its stability, heat resistance, etc., so that the material can play a good role in different environments. This substance, in the process of industrial production, can add color to many process links, ensure product quality and improve production efficiency. Therefore, 1,2-difluoro-4- (methylsulfonyl) benzene has shown its extraordinary value in various application fields and has made great contributions to scientific progress and industrial development.
Research & Development
There is now a product named 1,2-difluoro-4- (methylsulfonyl) benzene. As a chemical researcher, I will explore its research and application. The properties of this product have a specific chemical conformation and may have unique manifestations in various chemical processes.
Our research aims to clarify its physical and chemical properties, such as degree of melting and boiling, solubility, and activity in various reactions. Examine its interaction with other products, hoping to expand its use domain.
In the way of application, or in the system of medicine, with its characteristics, it can help to form new drugs and cure various diseases; or in the field of materials, add its properties to obtain excellent materials.
Looking forward to the future, I hope to study its nature in depth and expand its application. In time, it may emerge in the forest of chemical industry, adding luster to the research industry, and promoting its progress and expansion.
Toxicity Research
Taste all kinds of substances, the study of toxicity, is related to people's health, can't be careless
The toxicity of 1, 2 - Difluoro - 4 - (Methylsulfonyl) Benzene is quite important.
The author studies its toxicity and observes its chemical properties for the first time. 1, 2 - Difluoro - 4 - (Methylsulfonyl) Benzene has a unique structure, fluorine and methyl sulfonyl group, or cause it to be metabolized in the body.
Second look at its effect on living things. Take all living things as a test and observe how the physiological functions change after contact. Or damage the viscera, or the order of metabolism is the main point of the study.
Furthermore, study its spread in the environment. If this thing enters the environment, or is dispersed through water, soil, and air, all living beings are subject to its potential danger.
The study of toxicity is not immediate. It must be rigorous, accumulated over the years, and studied carefully in order to obtain its actual situation and protect sentient beings in the future.
Future Prospects
1,2-Difluoro-4- (methylsulfonyl) benzene is gradually emerging in today's chemical research. Although its application may not be widely used at present, the future prospects are very broad.
The development of chemistry and the rise of new substances often lead to changes. 1,2-difluoro-4- (methylsulfonyl) benzene has a unique structure, and its properties may be able to be used in materials science and drug research and development.
In materials science, or with its characteristics, new functional materials can be made to meet the needs of future high-tech. The way of drug research and development may become a key building block to help the creation of new drugs and solve the suffering of diseases in the world.
Our scientific researchers, with an enterprising heart, should explore its mysteries, and hope to make 1,2-difluoro-4- (methylsulfonyl) benzene shine in the near future, adding to the well-being of mankind.
Where to Buy 1,2-Difluoro-4-(Methylsulfonyl)Benzene in China?
As a trusted 1,2-Difluoro-4-(Methylsulfonyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Difluoro-4-(Methylsulfonyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-difluoro-4- (methylsulfonyl) benzene?
1% 2C2-diene-4- (methylthiazolyl) naphthalene, this substance has important uses in many fields.
In the process of pharmaceutical research and development, it is often used as a key intermediate. Through delicate chemical transformation, complex structures and specific biological activities can be built. Taking the creation of some antiviral drugs as an example, researchers cleverly use the special structure of the substance to add specific functional groups through a series of chemical reactions to shape drug molecules that can precisely target key viral proteins, thereby effectively inhibiting the replication and spread of viruses.
In the vast world of materials science, 1% 2C2-diene-4- (methylthiazolyl) naphthalene has also emerged. Due to its unique electronic structure and physical properties, it can be integrated into polymer materials. In this way, the optical properties of the material can be significantly improved, such as improving the fluorescence efficiency of the material, allowing it to bloom brighter and more stable in devices such as Light Emitting Diode (LED) and fluorescence sensors. At the same time, it can also enhance the electrical properties of the material, optimize its conductivity, and find a place in the field of organic semiconductor materials.
In the field of organic synthetic chemistry, it is like a magical key that unlocks the door to the construction of many complex organic molecules. With its lively double bonds and unique reactivity of thiazolyl groups, chemists can use various classic organic reactions, such as addition reactions, cyclization reactions, etc., to ingeniously construct organic compounds with novel structures and unique properties, injecting a steady stream of vitality into the vigorous development of organic synthetic chemistry.
What are the physical properties of 1,2-difluoro-4- (methylsulfonyl) benzene?
1% 2C2-diene-4- (methylthiazolyl) benzene, its physical properties are quite unique. This substance is usually in a solid state at room temperature, and its appearance is mostly white or white-like crystalline. The texture is more delicate and uniform.
Looking at its melting point, it is within a certain temperature range. This melting point characteristic is a key guide when identifying and purifying the substance. Its boiling point also has a corresponding range. At this temperature, the substance changes from liquid to gaseous state. The value of this boiling point is crucial for controlling its phase change in chemical processes.
When it comes to solubility, in common organic solvents, such as ethanol, ether, etc., the substance exhibits certain solubility characteristics. In ethanol, under specific temperature and concentration conditions, partial dissolution can be achieved. This dissolution property provides a lot of room for operation in related chemical reactions and preparations. In water, its solubility is relatively weak, which is closely related to the hydrophilicity and hydrophobicity of the groups contained in its molecular structure.
Furthermore, the density of the substance is also an important physical property. Compared with the density of water, its value may be different. This density difference may play an important role in the operation process such as liquid-liquid separation, which may help the development of separation and purification processes.
In addition, the stability of 1% 2C2-diene-4- (methylthiazolyl) benzene to light and heat is also one of its physical properties. In light or high temperature environments, its structure may gradually change. When storing and using this material, special attention should be paid to selecting suitable storage conditions to ensure the stability of its chemical structure and properties.
What are the chemical properties of 1,2-difluoro-4- (methylsulfonyl) benzene?
1% 2C2 -diethyl-4- (methylsulfonyl) benzene has multiple chemical properties. Its structure contains diethyl groups and methylsulfonyl groups, which give it unique reactivity.
From a nucleophilic point of view, the sulfur atom in the sulfinyl group has a lone pair of electrons, so that the compound has a certain nucleophilic ability. In a suitable reaction system, it can be used as a nucleophilic reagent to attack electrophilic substrates. For example, when reacting with halogenated hydrocarbons, the sulfur atom nucleophilic attacks the carbon atom in the halogenated hydrocarbons, and the halogen ions leave to form new sulfur-containing organic compounds.
As far as redox properties are concerned, sulfinyl groups are located between various oxidation states of sulfur elements and have certain redox activity. In case of strong oxidizing agents, sulfur atoms can be further oxidized to form higher valence sulfur oxides; in case of suitable reducing agents, they can be reduced to low-priced sulfur-containing compounds.
Its substituents also have an impact on the electron cloud distribution of the benzene ring. The diethyl group is the power supply group, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution reactions, and the substitution reactions mainly occur in the ortho and para-sites of the benzene ring; the methylsulfonyl group is the electron-withdrawing group, which can reduce the electron cloud density of the benzene ring, which affects the electrophilic sub
In addition, the physical properties such as solubility of the compound are related to molecular polarity. It contains a polar sulfinyl group, which makes it have a certain solubility in polar solvents, but the diethyl group has a certain hydrophobicity, and the overall solubility will change with the properties of the solvent and the interaction of various groups in the molecular structure. In the fields of organic synthesis and medicinal chemistry, these chemical properties determine that it can participate in the construction of a variety of complex compounds as a key intermediate.
What are the preparation methods of 1,2-difluoro-4- (methylsulfonyl) benzene?
To prepare 1,2-diene-4- (methylthiazolyl) naphthalene, the following ancient methods can be used.
First, the naphthalene is used as the starting material. First, the naphthalene is subjected to a specific substitution reaction, and a suitable functional group is introduced. This functional group needs to be able to be skillfully converted in the subsequent reaction to gradually construct the target structure. The activity of the naphthalene ring can be used to introduce halogen atoms at specific positions in the naphthalene ring with suitable reagents. The introduction check point and quantity of halogen atoms must be precisely controlled, which is related to the direction and success of the subsequent reaction. After that, with the help of organometallic reagents, such as Grignard reagents, halogenated naphthalenes are coupled with alkenyl-containing halogens to form preliminary alkenyl-containing naphthalene derivatives.
Second, it is related to the introduction of thiazolyl. It can start from simple compounds containing nitrogen and sulfur, such as glyoxal, thiourea, etc. The thiazole ring precursor is reacted with thiourea under specific conditions to construct the thiazole ring precursor. After suitable functional group transformation, the thiazole ring precursor is connected to the above-mentioned enyl-containing naphthalene derivative. This connection step requires a gentle and efficient reaction path to avoid damage to the formed enyl and naphthalene ring structures. Or a coupling reaction catalyzed by transition metals can be used to carefully adjust the reaction temperature, time and reagent ratio to promote the precise combination of the two.
Third, the diene structure is constructed. When the naphthalene ring, thiazolyl and some alkenyl structures have been formed, the molecular structure needs to be further modified to obtain the 1,2-diene structure. The elimination reaction can be used to select suitable bases and reaction conditions to remove small molecules, such as hydrogen halide, from the intra-molecular localization to form carbon-carbon double bonds. In this process, it is necessary to ensure the regioselectivity and stereoselectivity of the elimination reaction, so that the double bond is formed at the target position and the configuration meets the requirements of 1,2-diene. The whole process requires fine separation and identification of the intermediate products in each step of the reaction to ensure that the final pure 1,2-diene-4- (methylthiazolyl) naphthalene can be obtained.
What are the precautions for storing and transporting 1,2-difluoro-4- (methylsulfonyl) benzene?
1% 2C2-diene-4- (methacryloyl) naphthalene requires attention to many key matters during storage and transportation.
It is an organic compound with certain chemical activity. When storing, it should be placed in a cool, dry and well-ventilated place. Because it is sensitive to heat and light, high temperature or strong light can easily cause decomposition or deterioration, so the warehouse should be shaded and the temperature should be controlled within a specific range to prevent safety hazards and quality deterioration.
Furthermore, it should be stored separately from oxidants, acids, bases, etc. Because the substance comes into contact with these chemicals, or causes severe chemical reactions, such as oxidation, acid-base neutralization, etc., fire, explosion and other serious consequences. At the same time, the storage area should be clearly marked to inform personnel of the danger.
During transportation, it is necessary to ensure that the packaging is intact. Packaging materials should be able to withstand certain external shocks and environmental changes to prevent leakage. The means of transportation should also be clean, dry, and free of other chemicals to avoid cross-contamination. And the relevant regulations and standards should be followed during transportation, and the necessary emergency treatment equipment and protective equipment should be equipped to prevent accidents from happening quickly.
In addition, whether it is storage or transportation, operators must undergo professional training and be familiar with the characteristics of the substance, safety operating procedures and emergency response methods, so as to ensure the safety and stability of 1% 2C2-diene-4- (methacryloyl) naphthalene during storage and transportation.