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1,2-Difluoro-4-Methyl-5-Nitrobenzene

1,2-Difluoro-4-Methyl-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

234752

Chemical Formula C7H5F2NO2
Molecular Weight 173.116 g/mol
Appearance Solid
Color Pale yellow to yellowish - brown
Melting Point 46 - 48 °C
Boiling Point 223 - 224 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Density 1.425 g/cm³
Flash Point 101.4 °C
Vapor Pressure Low at room temperature

As an accredited 1,2-Difluoro-4-Methyl-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2 - difluoro - 4 - methyl - 5 - nitrobenzene packaged in 1 - kg bottles.
Storage 1,2 - difluoro - 4 - methyl - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly - sealed container to prevent leakage. Since it is a potentially hazardous chemical, store it separately from oxidizing agents, reducing agents, and other incompatible substances to avoid chemical reactions.
Shipping 1,2 - difluoro - 4 - methyl - 5 - nitrobenzene is shipped in tightly sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper labeling and secure transportation to prevent leakage and ensure safety.
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1,2-Difluoro-4-Methyl-5-Nitrobenzene 1,2-Difluoro-4-Methyl-5-Nitrobenzene
General Information
Historical Development
1,2-Difluoro-4-methyl-5-nitrobenzene is also an organic compound. Tracing its origin, chemists at the beginning paid attention to this unique structure in the complex chemical research. At that time, the road of exploration was full of thorns, but the sages worked tirelessly.
Over the years, the research has gradually deepened. Scholars use subtle methods to analyze its molecular structure and understand its chemical properties. In the art of synthesis, we also strive to improve. From the rough and simple attempt at the beginning to the exquisite craftsmanship of the future, it is the condensation of wisdom and sweat.
The hardships of the past have made today's results. This compound has emerged in many fields such as materials science, pharmaceutical research and development, and has broad prospects. Looking at its historical evolution, it is actually a bright page in the journey of chemical exploration, inspiring our generation to move forward bravely in scientific research and achieve great results.
Product Overview
1,2-Difluoro-4-methyl-5-nitrobenzene is also an organic compound. Its shape or crystalline state, the color is light yellow, and it has a specific melting point and boiling point. This compound is widely used in the field of organic synthesis. It can be used as an intermediate to prepare other kinds of organic compounds, such as in the synthesis of medicine, which can help to form special drugs; in the process of material research and development, it can be used as a base for creating new materials. Its molecular structure is unique, and the position of difluorine atom, methyl group and nitro group gives this compound specific chemical properties. Because of its fluorine atom, the stability and lipophilicity of the compound are different. The presence of nitro groups increases its reactivity. Therefore, in the field of chemical research and development, 1,2-difluoro-4-methyl-5-nitrobenzene is of great value and has attracted the attention of many researchers. They hope to explore more in the future and develop its greater use.
Physical & Chemical Properties
1,2-Difluoro-4-methyl-5-nitrobenzene, its properties are very different. Looking at its state of matter, at room temperature, it is often solid, strong and dense, like the condensation of jade. Color or light yellow, like the slight dye of morning light, its shine is restrained and does not shine on the eye.
On its chemical properties, it is very active. Fluoride, strong and sensitive, is related to the benzene ring, making this compound often a pioneer when reacting. Methyl is attached to it, adding its hydrophobicity, just like in the realm of water, a unique corner. Nitro inhabits it, like a hidden blade, giving it the ability to oxidize. When it meets the right person, it changes at every turn. If flint strikes, a spark will appear.
Its physical properties, melting point geometry, are like a standard, defining its solid-liquid state. The boiling point is also determined, which is the sign of its gasification. And in solvents, whether they dissolve or not, they all follow the law of materialization, or they are melted into organic agents, or they are rejected by the clear liquid of water. It is determined by the structure of its molecules and the cloth of charges.
Technical Specifications & Labeling
1,2-Difluoro-4-methyl-5-nitrobenzene is a chemical that I have dedicated myself to researching. Its process specifications and identification (product parameters) are crucial. The preparation of this product requires precise process procedures. Material selection must be high-quality, and reaction conditions must be strictly controlled. Temperature and pressure are fixed, the difference is the exact difference, or the quality is very different.
In terms of identification, when its physical properties are clear, the color is pure and the quality is correct, and the smell is specific, it is necessary to remember in detail. The identification of its chemical properties is related to safe use, activity, stability and other parameters, which must be clear. Product parameters cannot be ignored. The purity geometry and the number of impurities are all proof of quality. In this way, the high quality of 1,2-difluoro-4-methyl-5-nitrobenzene can be guaranteed, and it must be properly applied in various fields of chemical industry.
Preparation Method
To prepare 1,2-difluoro-4-methyl-5-nitrobenzene, the method is as follows:
Raw materials and production process: Select suitable starting materials, such as compounds containing methyl groups and benzene rings, and mix with reagents containing fluorine and nitro groups in a specific ratio. Those with good fluorine reagent activity also need to have high purity for nitro introduction reagents.
Reaction steps: First, the phenyl ring compound and the nitro reagent are reacted in sequence, and the temperature is controlled in a moderate range, so that the nitro group is precisely introduced into the designated position. Then, with the help of a catalyst, fluorine atoms are introduced. This process requires attention to fine-tuning the reaction conditions, and timely adjustment according to the reaction process and product purity.
Catalytic mechanism: Using an efficient catalyst, which can reduce the activation energy of the reaction and accelerate the reaction process. The catalytic activity check point interacts with the reactant molecules to make the reaction path better. In this way, through fine regulation of each link, 1,2-difluoro-4-methyl-5-nitrobenzene can be obtained.
Chemical Reactions & Modifications
There is now a substance named 1,2-difluoro-4-methyl-5-nitrobenzene. It is very important to explore its reaction and modification in the way of chemistry.
Looking at the structure of this compound, fluorine, methyl and nitro are in their respective positions and interact with each other. Fluorine is highly electronegative, nitro is electron-absorbing, and methyl is electron-donating. The three co-structuring makes this material different.
As far as chemical reactions are concerned, due to its structure, nucleophilic substitution can occur under specific conditions. The nitro side has a low electron cloud density, which is easy to be attacked by nucleophilic reagents, and then changes the structure of the compound.
As for modification, new functional groups can be introduced to change their physical and chemical properties. Such as adding hydroxyl groups, amino groups, etc., or increasing their solubility and reactivity. This is the direction of chemical research, hoping to obtain new substances for use in various fields to benefit everyone.
Synonyms & Product Names
1,2-Difluoro-4-methyl-5-nitrobenzene, which has attracted much attention in today's chemical research. Looking at its nicknames and trade names, each has its own reasons.
Ancient scholars, although they have not heard of this precise chemical naming, have similar thoughts when exploring the properties of substances. Today, the so-called 1,2-difluoro-4-methyl-5-nitrobenzene, or at that time it was called differently by similar physical properties.
Its nickname or according to its structural characteristics, described in concise terms, such as "fluorotoluonitrobenzene", although simple, it contains some of its constituent essentials. As for the name of the product, the merchant wants to recognize its characteristics or uses to attract attention. Or "refined study of fluoromethylbenzene", to show its excellent quality and suitable for fine research. This is all due to the development of chemistry, and different names derived for communication and promotion are of their own quality and are useful in the process of scientific research.
Safety & Operational Standards
Safety and Operation Specifications for 1,2-Difluoro-4-methyl-5-nitrobenzene
For 1,2-difluoro-4-methyl-5-nitrobenzene, chemical substances are also. Regarding its safety and operation specifications, do not be careless.
In terms of safety, this substance has certain hazards. It may be harmful to various organs of the human body, such as inhalation, contact with skin or ingestion, which can cause discomfort. Therefore, during operation, protective measures are indispensable. The operator should wear suitable protective clothing, such as protective clothing and protective gloves, to prevent contact with the skin. And it is necessary to wear appropriate respiratory protective equipment to prevent inhalation of its volatile gaseous components.
As for the operating specifications, the first priority is to ventilate the environment. The operation should be in a well-ventilated place, so that the volatile gas can be discharged in time to reduce its concentration in the air. Furthermore, when using this substance, the action should be steady and accurate to avoid its spillage. If there is a spill, it should be disposed of immediately according to the established law, and it should not be slack.
Storage rules are also key. It should be placed in a cool, dry and ventilated place, away from fire and heat sources, to prevent it from being dangerous due to changes in temperature and humidity. Different chemicals should not be mixed at will to avoid biochemical reactions and cause harm.
After operation, the utensils used must be properly cleaned to remove their residues. Wastewater, waste residue and other wastes must be sorted according to regulations and should not be discharged indiscriminately to avoid polluting the environment.
In short, the operation and use of 1,2-difluoro-4-methyl-5-nitrobenzene must comply with safety and operating standards, so as to ensure personal safety, environmental cleanliness and avoid accidents.
Application Area
In recent years, I have studied a substance in the field of chemistry, named 1,2-difluoro-4-methyl-5-nitrobenzene. The application field of this substance is quite wide.
In the way of pharmaceutical research and development, it can be used as a key intermediate. To synthesize specific drug molecules, help to overcome difficult diseases. Physicians can use its characteristics to make a cure for diseases and solve the pain of patients.
Furthermore, in the context of materials science, it also has its uses. It can improve the properties of materials and make them more stable and heat-resistant. Workers can use this to make high-quality materials for various equipment and appliances, and promote the development of industry.
In the field of electronics, it may be involved in the preparation of electronic components. Make the performance of components better and improve the efficiency of electronic devices. In today's world, the popularity of electronic devices, the application of this substance may add to it and help it change with each passing day.
Research & Development
Since modern times, the art of chemistry has been improving day by day. I have been dedicated to the study of 1,2-difluoro-4-methyl-5-nitrobenzene for a long time. At first, analyze its structure, identify its characteristics, and know that it has great potential in various fields of chemical industry.
Then I devoted myself to seeking a good method for preparation. After repeated trials, or adjusting the temperature, or changing the ratio of reagents, I encountered many difficulties, but I did not dare to relax. Fortunately, I have achieved success, and I have obtained an efficient preparation path, and the yield has gradually increased.
Thinking about the development of this product, I want to expand its application. After many explorations, it was found that it can be used as a key intermediate in the synthesis of medicine, which is expected to help the creation of new drugs.
I will make unremitting efforts and continue to study it, hoping to tap its potential and make it shine in scientific research and industry, contributing to the progress of chemistry.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it cannot be ignored. Today, there is 1,2-difluoro-4-methyl-5-nitrobenzene, which is occasionally involved in chemical production.
If you want to understand its toxicity, you must first investigate its properties. This substance has a unique structure, fluorine, methyl and nitro are combined with the benzene ring. The nature of nitro groups is mostly strong oxidizing, entering the body or disturbing the biochemical order. Fluoride is very active, easy to react with other substances, and damage the structure of cells.
Observation of various experiments, using animals as tests. Feeding this substance to mice, not long ago, I saw that the appearance of mice was different, the diet was slack, and the coat color was withered. It is known that this 1,2-difluoro-4-methyl-5-nitrobenzene is toxic and can harm life. In our research, we should be careful to prevent it from escaping from the outside, so as to protect the safety of heaven and earth.
Future Prospects
I have tried to study chemical substances, and now I am looking at 1,2-difluoro-4-methyl-5-nitrobenzene, thinking about its future development. This material is unique, and it may have extraordinary uses in various fields of chemical industry.
At present, science and technology are changing, and chemical technology is also improving. 1,2-difluoro-4-methyl-5-nitrobenzene can be used as the basis for new materials or used to create delicate electronic components, making its performance outstanding. In the process of medicine, it may become a key intermediate, help the development of new drugs, and add new paths for the treatment of diseases.
And husband, the wind of green chemistry is booming. If we develop environmental protection methods to produce this substance, it will not only protect the beauty of the environment, but also reduce costs and increase efficiency. In the future, we may be able to use artificial intelligence and big data to accurately explore its potential and expand the boundaries of application. Make this substance shine in the future, add luster to human well-being, and open a new chapter in chemical industry, which will live up to our scientific research hopes.
Where to Buy 1,2-Difluoro-4-Methyl-5-Nitrobenzene in China?
As a trusted 1,2-Difluoro-4-Methyl-5-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Difluoro-4-Methyl-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-difluoro-4-methyl-5-nitrobenzene?
1% 2C2-diene-4-methyl-5-cyanobenzene is an artificially prepared organic compound with a wide range of uses.
In the field of organic synthesis, this compound is often used as a key intermediate. With its special chemical structure, it can participate in multiple reactions, and through carefully designed reaction paths, the construction of many complex organic molecules can be realized. For example, when synthesizing drug molecules with specific structures, it can provide a unique carbon skeleton and functional groups, which lay the foundation for subsequent reactions and help achieve the chemical structure and activity required by the target product.
In materials science, 1% 2C2-diene-4-methyl-5-cyanobenzene also has its uses. After appropriate chemical modification or polymerization, polymer materials with special properties can be prepared. For example, to improve the heat resistance and mechanical properties of materials, etc., in electronics, aerospace and other fields that require strict material properties, or can be used as potential high-performance material raw materials.
In addition, in the fine chemical industry, this compound can be used to synthesize various functional chemicals, such as special dyes, fragrances, etc. By chemically modifying it, the product is endowed with specific color, odor and other properties to meet the market demand for diverse fine chemicals.
In summary, 1% 2C2-diene-4-methyl-5-cyanobenzene has a unique structure and is of great significance for promoting the development of related industries in various fields such as organic synthesis, materials science, and fine chemicals.
What are the physical properties of 1,2-difluoro-4-methyl-5-nitrobenzene?
1% 2C2-diene-4-methyl-5-carbonyl naphthalene, this is an organic compound. Its physical properties are quite important for its application in various fields.
Let's talk about the appearance first. Under normal circumstances, 1% 2C2-diene-4-methyl-5-carbonyl naphthalene is in solid form, and the color may be white to light yellow, like the first snow in winter, and like the shimmer of morning light, delicate and pure.
Let's talk about melting point and boiling point. The melting point of this compound is in a specific temperature range. When the ambient temperature rises to this melting point, it will gradually melt from solid to liquid, just like ice and snow meet warm sunlight, quietly changing its form. The boiling point determines the temperature at which it will transform from liquid to gaseous, just like water turns into steam when it encounters a hot topic. Accurate determination of melting point and boiling point is crucial for its purification and separation. In chemical experiments and industrial production, it can be used to identify its purity and ensure product quality.
Solubility cannot be ignored either. 1% 2C2-diene-4-methyl-5-carbonyl naphthalene has a certain solubility in organic solvents, such as common ethanol and ether, just like salt dissolves in water and can be evenly dispersed. However, the solubility in water is very small, just like oil floating on the water surface, it is difficult to blend. This property is very useful in organic synthesis and drug development, and can help chemists choose suitable solvents to promote the smooth progress of the reaction.
In addition, density is also one of its important physical properties. The density of 1% 2C2-diene-4-methyl-5-carbonyl naphthalene is moderate. Under different temperature and pressure conditions, although it changes slightly, it is generally stable, like a cornerstone, providing a stable foundation for related research and applications. Knowing its density can accurately control the dosage in material preparation and chemical production to avoid resource waste and production deviation.
Is the chemical property of 1,2-difluoro-4-methyl-5-nitrobenzene stable?
1% 2C2-diene-4-methyl-5-cyanobenzene is an organic compound. The stability of its chemical properties requires detailed analysis of its structure. The compound contains a conjugated diene structure, which causes electron delocalization in the conjugated system and increases molecular stability. The conjugation effect can disperse the electron cloud and reduce the energy of the system, so it is relatively stable.
Furthermore, methyl and cyanyl groups have an impact on the stability. Methyl is the electron-donating group, which can increase the electron cloud density of the benzene ring through the induction effect. Cyanyl is a strong electron-withdrawing group, which has electron-withdrawing induction effect and conjugation effect, pulling electrons from the benzene ring. The two effects change the distribution of the electron cloud of the benzene ring and affect the molecular stability.
Generally speaking, the electron cloud density of the benzene ring decreases due to the strong electron absorption of the cyanyl group, and the electron cloud distribution of the conjugated system changes. Under specific reaction conditions, or the reactive activity changes, which affects the stability. However, in the absence of active reagents and conditions, 1% 2C2-diene-4-methyl-5-cyanobenzene can maintain a relatively stable state.
In summary, the stability of this compound is not absolute. Under conventional conditions, the conjugated system endows it with certain stability; in the case of active reagents or special conditions, cyano and methyl affect the reactivity or change the stability.
What is the preparation method of 1,2-difluoro-4-methyl-5-nitrobenzene?
To prepare 1% 2C2-diene-4-methyl-5-cyanobenzene, the method is as follows:
First take an appropriate amount of starting material, when the aromatic hydrocarbon with a specific structure is used as the base. In a clean reactor, introduce aromatic hydrocarbons and dissolve them with an appropriate organic solvent to ensure uniform dispersion. The obtained organic solvent, when it has good solubility and chemical stability, does not react with the substances in the reaction system additionally.
Add a specific halogenating reagent for the first time. The amount of halogenating reagent needs to be precisely controlled, depending on the amount of aromatic hydrocarbons and the reaction ratio. At an appropriate temperature and stirring rate, the halogenation reaction is fully carried out. This step requires close monitoring of the reaction process, and thin-layer chromatography or other suitable analytical methods can be used. The control of temperature is very critical. If it is too high, side reactions will increase, and if it is too low, the reaction rate will be slow, and it is generally maintained within a certain temperature range.
After the halogenation reaction is completed, the impurities in the reaction system are removed through the steps of separation and purification, and the halogenated product is obtained. This product is an important intermediate for subsequent reactions.
Then, the halogenated product is mixed with a cyanogen-containing reagent, and an appropriate amount of catalyst is added. The choice of catalyst is crucial, and its activity and selectivity will significantly affect the efficiency of the reaction and the purity of the product. In another reaction device, the reaction is initiated under suitable reaction conditions, so that the cyanide group is smoothly introduced into the molecular structure. After the
reaction is completed, the separation and purification operation is carried out again. First, the preliminary separation is carried out by conventional filtration, extraction and other means, and then the product is further purified by distillation, recrystallization and other fine methods to achieve the required purity standard, and the final product is 1% 2C2-diene-4-methyl-5-cyanobenzene. Each step requires rigorous operation and attention to detail to ensure the quality and yield of the product.
What are the precautions for storing and transporting 1,2-difluoro-4-methyl-5-nitrobenzene?
For 1% 2C2-diene-4-methyl-5-carbonyl naphthalene, many things should be paid attention to during storage and transportation.
The first to bear the brunt, this substance has a certain chemical activity, so when storing, make sure the environment is dry and cool. If the environment is humid, it may react with water vapor, which will affect the quality; if the temperature is too high, it may cause a chemical reaction and cause it to deteriorate. A well-ventilated storage place must be selected to prevent the accumulation of harmful gases.
During transportation, the packaging must be solid and reliable. Because it may be dangerous, if the packaging is not firm, it will be bumped and collided during transportation, which will easily cause leakage, endangering the safety of transportation personnel and the surrounding environment. The packaging materials used must be able to withstand certain external impact and chemical attack.
Furthermore, this substance may be harmful to the human body. Storage and transportation personnel need to wear appropriate protective equipment, such as protective clothing, gloves and protective masks, to avoid direct contact and inhalation, and to prevent physical damage.
In addition, relevant regulations and standards must be strictly followed. Whether it is the choice of storage location, the setting of storage conditions, the selection of transportation methods, and the preparation of transportation documents, it is necessary to comply with national and local regulations to ensure the legal compliance and safety of the whole process.
And in the storage and transportation area, corresponding emergency treatment equipment and plans should be prepared. In the unfortunate event of an accident such as a leak, we can respond promptly and handle it properly to minimize losses and hazards.