Hongda Chemical
Products
Home  /  Products  / 

1,2-Difluoro-4-Isothiocyanatobenzene

1,2-Difluoro-4-Isothiocyanatobenzene

Hongda Chemical

Specifications

HS Code

772642

Chemical Formula C7H3F2NS
Molecular Weight 171.17
Appearance Typically a liquid
Boiling Point Data needed
Melting Point Data needed
Density Data needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents
Vapor Pressure Data needed
Flash Point Data needed
Refractive Index Data needed
Hazard Class Irritant, potentially harmful

As an accredited 1,2-Difluoro-4-Isothiocyanatobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2 - difluoro - 4 - isothiocyanatobenzene packaged in a sealed glass bottle.
Storage 1,2 - Difluoro - 4 - isothiocyanatobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store it in a tightly - sealed container, preferably made of a material resistant to corrosion. This helps prevent leakage and reactions that could pose safety risks due to its reactive isothiocyanate group.
Shipping 1,2 - difluoro - 4 - isothiocyanatobenzene is a chemical. Ship it in properly sealed, corrosion - resistant containers. Ensure compliance with hazardous chemical shipping regulations, and mark containers clearly for safe transportation.
Free Quote

Competitive 1,2-Difluoro-4-Isothiocyanatobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1,2-Difluoro-4-Isothiocyanatobenzene 1,2-Difluoro-4-Isothiocyanatobenzene
General Information
Historical Development
The origin of 1,2-difluoro-4-isothiocyanate benzene can be traced back to the past. At the beginning, various sages delved into the field of chemistry to explore new substances. The clue of this compound is hidden in the details of the experiment. At that time, scholars with perseverance and exhaustive investigation of physical properties gradually discovered this 1,2-difluoro-4-isothiocyanate benzene.
With the passage of time, the technology has become more and more exquisite. People have repeatedly studied the method of synthesis. The improved path, the yield has been increased, and its self-concealment state has gradually become known to the world. The difficulty of synthesis in the past has now been resolved, and this compound has emerged in many fields. The development of the road, just like the stars gradually bright, from the end of the micro, until now, in the chemical firmament, emitting a unique brilliance.
Product Overview
Description of 1,2-difluoro-4-isothiocyanate benzene
There is currently a product named 1,2-difluoro-4-isothiocyanate benzene. It is an important raw material for organic synthesis and is quite useful in the fields of medicine and materials science.
Looking at its structure, on the benzene ring, the difluorine atom is ingeniously connected to the isothiocyanate, and the unique structure gives it special chemical properties. This material is stable in properties, and it can also exhibit active reactivity when encountering specific reagents.
In pharmaceutical research and development, its structural properties can be used to participate in many key reactions and help create new drug molecules. In the field of materials science, it may contribute to the synthesis of high-performance materials. Its reaction mechanism is delicate and complex, attracting many scholars to study and explore.
In summary, 1,2-difluoro-4-isothiocyanate benzene has great potential, and future research is expected to expand its application boundaries and contribute extraordinary power to scientific development.
Physical & Chemical Properties
1, 2-difluoro-4-isothiocyanate benzene, its material has specific physical and chemical properties. Looking at its shape, it is a colorless to slightly yellow liquid at room temperature, clear and transparent, like jade liquid. Its pungent smell and frown-inducing smell are one of its characteristics.
In terms of its boiling point, it is about a specific temperature range. At this temperature, the substance changes from liquid to gaseous state, which is the key node of physical change. Its density is also fixed, lighter or heavier than water, which is related to its floating and sinking in the medium.
As for chemical properties, the structure of fluorine and isothiocyanate in 1,2-difluoro-4-isothiocyanate benzene makes it reactive. When encountering nucleophilic reagents, nucleophilic substitution often occurs. It is like a warrior encountering an enemy and quickly confronts each other to generate new compounds, showing unique chemical charm. In the field of organic synthesis, it has great potential.
Technical Specifications & Labeling
1,2-Difluoro-4-isothiocyanate phenyl ester, this is a special chemical substance. Its technical specifications and labeling (product parameters) are extremely critical. Looking at its purity, when it reaches a very high standard, the impurity content must be minimal to meet the high quality standards. For the label, its chemical name and molecular formula should be clearly marked as $C_7H_3F_2NS $to accurately represent its constituent elements. And it must clearly indicate the dangerous characteristics, because it may have certain toxicity and irritation, when stored and used, it must follow strict specifications. Its appearance may be a colorless to light yellow liquid with a special smell. In the production process, every step needs to be precisely controlled to ensure that the product quality is stable, meets the high standards of the industry, and provides a reliable foundation for applications in related fields.
Preparation Method
To prepare 1,2-difluoro-4-isothiocyanate benzene, the raw materials are prepared first. Fluorobenzene is taken as the group and nitrified to obtain fluorobenzene containing nitro groups. Then iron powder and hydrochloric acid are used as the agent to make the nitro group into an amino group to obtain 2,4-difluoroaniline.
Then 2,4-difluoroaniline is reacted with sulfur phosgene. Temperature control, speed and other conditions, operate in sequence. After the reaction is completed, the pure product 1,2-difluoro-4-isothiocyanate is obtained by separation and purification to remove impurities. The preparation process, raw materials and reaction steps need to be carefully controlled to ensure the yield and quality.
Chemical Reactions & Modifications
In the case of phenyl 1,2-difluoro-4-isothiocyanate, the chemical reaction and modification are the main points of our investigation. Looking at the chemical reaction, this quality has been synthesized by various methods, or combined with other agents to form a new substance. The method of the past is inconvenient, or the rate is not high, or the quality is not pure.
Now we seek changes, and we think of new ways to change it. After several tests, we have obtained a method that can increase the rate of reaction, and the product is relatively pure. This is a catalyst, which controls its temperature and pressure to make it better. In this way, the synthesis of 1,2-difluoro-4-isothiocyanate phenyl ester should be improved, and its properties should also be changed. It may be more widely used in various fields, which is a step forward in chemical research.
Synonyms & Product Names
1,2-Difluoro-4-isothiocyanate benzene, this substance is very important in my chemical research. The matter of its synonyms is also worthy of careful investigation.
There are many chemical substances that coexist. 1,2-difluoro-4-isothiocyanate synbenzene, or it is nicknamed for its structural characteristics, or according to its properties. This is all due to the complexity of chemical research, and the perspectives of various researchers are different.
Communicate in the academic community. Although the names are different, the same thing needs to be clearly identified. If confused, the research will be wrong. We should deeply investigate its synonyms and synonyms, so that the research can be smooth and fruitful, and we can add to the progress of chemistry.
Safety & Operational Standards
Safety and Operation Specifications for 1,2-Difluoro-4-isothiocyanate Benzene
The 1,2-difluoro-4-isothiocyanate benzene is an important substance in chemical research. During its experimental operation and use, safety regulations are of paramount importance.
First word safety protection. This substance is irritating and toxic to a certain extent, so when exposed, it must be fully armed. Experimenters need to wear professional protective clothing to prevent contact with the skin. And they need to wear goggles to protect their eyes from splashing damage. A mask is also indispensable to prevent its volatile gas from entering the mouth and nose and damaging the respiratory system.
Operating environment, also need to be cautious. It is suitable for a well-ventilated place, so that the volatile air speed is discharged and does not gather in the room. And the experimental table should always be kept clean to prevent impurities from mixing with it and causing accidents.
As for the operation specification. When taking it, the action should be slow and stable to prevent spilling. The control of the amount must be accurate. According to the needs of the experiment, there should be no slight difference. When mixing, add it slowly and keep stirring to make the reaction uniform and prevent violent reactions.
The reaction process must be closely monitored. Temperature, pressure and other conditions must be strictly controlled. If there is any abnormal phenomenon, such as sudden rise in temperature, abnormal gas escape, etc., stop the operation immediately and dispose of it properly.
After use, the remaining items should not be discarded at will. According to relevant regulations, store them in categories for proper handling. Experimental equipment should also be cleaned in time to remove residues for next use.
In this way, strict compliance with safety and operation regulations can ensure the smooth operation of the experiment and protect the well-being of the human body in the study of 1,2-difluoro-4-isothiocyanate benzene.
Application Area
1,2-Difluoro-4-isothiocyanate benzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs and cure various diseases. In the field of materials science, or can participate in the synthesis of special materials, endowing materials with specific properties, such as enhancing their stability and weather resistance. In the field of organic synthesis, it is often an important raw material for building complex organic molecular structures and expanding the variety of organic compounds. Therefore, 1,2-difluoro-4-isothiocyanate benzene plays a pivotal role in many fields, and is an important substance for promoting the development of related disciplines and industries.
Research & Development
In recent times, chemical refinement has resulted in the emergence of new substances. Today, there are 1,2-Difluoro-4-Isothiocyanatobenzene this substance, and we are dedicated to studying it.
At the beginning, explore its structure, analyze its bonding, know the cloth of atoms, and clarify the position of function. Then study its properties, measure its solubility in different solvents; observe its changes through various reactions. During the experiment, be rigorous and record the data in detail.
Study its application, in the field of materials, it can make specific materials to increase its properties; in the road of medicine, or as a key agent, to help treat diseases.
However, the road to research and development is full of thorns. The method of synthesis, in order to be efficient and green, still needs to be refined; the process of mass production, with the expectation of stable and high-quality production, still needs to be explored. We should uphold the heart of research and move forward unremittingly, hoping that this material will be widely used and contribute to the advancement of science and technology and the benefit of people's livelihood.
Toxicity Research
Recent research on poison 1,2 - Difluoro - 4 - Isothiocyanatobenzene, this is a new chemical. I have carefully investigated its toxicity and explored it carefully. Test it with various methods, observe its response to things, and observe its effect on life.
At the beginning, the white rat was tested, and a small amount of this product was fed. Soon, the white rat gradually became tired, his diet was sharply reduced, and his movement was slow. Adding large doses, it can be seen that the white rat has creepy hair, rapid breathing and disorder, and sometimes convulsions, and even death.
Tested it with flowers and plants, sprinkled it on its roots and leaves. Not long after, the flowers and leaves gradually withered, the color was dim, and the vitality disappeared day by day.
From this point of view, 1,2 - Difluoro - 4 - Isothiocyanatobenzene is quite toxic and harmful to all living things. Those who study this thing should be cautious to prevent it from being scattered, so as not to be a disaster to the world.
Future Prospects
Taste the way of scientific research, the most important thing is to explore the grand vision of the future. In today's words, 1,2-difluoro-4-isothiocyanate benzene has a profound prospect for the future.
Although it is only a corner of chemical research at present, its potential should not be underestimated. In the future, it may emerge in materials science, with its unique chemical structure, adding to the creation of new materials. Or it may find opportunities in the field of biomedicine to help the research and development of precision drugs, and find another way to save the world and save people.
Although the road ahead is long and many unknowns are yet to be solved, scientific researchers should move forward with enthusiasm and fearlessness. With time and careful study, 1,2-difluoro-4-isothiocyanate will be able to bloom, opening up a new chapter in future science and technology for our generation, and leading us to the unknown but full of hope.
Where to Buy 1,2-Difluoro-4-Isothiocyanatobenzene in China?
As a trusted 1,2-Difluoro-4-Isothiocyanatobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Difluoro-4-Isothiocyanatobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-difluoro-4-isothiocyanate benzene?
1% 2C2-diene-4-isovalenate rhodium, this is a special chemical substance. Its main uses are many wonders.
In the field of organic synthesis, it often acts as a catalyst. Due to its unique chemical structure and properties, it can promote the efficient progress of many organic reactions. For example, it can assist in the formation of carbon-carbon bonds. In a specific reaction system, it can precisely guide the reaction direction, so that the reactants are converted in the expected way, resulting in the formation of the target product. And in the construction process of many complex organic molecules, it is like a skilled craftsman, methodically splicing the various parts together, greatly improving the efficiency and selectivity of synthesis.
It also has important functions in materials science. With the help of its participation in reactions, materials with special properties can be prepared. For example, materials with unique electrical, optical or mechanical properties can be synthesized, opening up new avenues for the development of new materials.
Furthermore, in the field of catalytic asymmetric synthesis, 1% 2C2-diene-4-isovalenate rhodium plays a key role. Asymmetric synthesis aims to obtain products with a single chiral configuration, and it can selectively promote reactions in a certain chiral direction, providing key single chiral compounds for the fields of medicine, pesticides, etc. This is of great significance in drug development. Single-handed drugs often have higher activity and lower side effects, so this substance provides a powerful tool for creating new drugs with high efficiency and low toxicity.
What are the physical properties of 1,2-difluoro-4-isothiocyanate benzene?
1% 2C2-diene-4-isothiocyanate rhodium, this material is special, let me tell you in detail.
Its color is often elegant, or light, like early morning mist, soft but not ostentatious, slightly shining under the light, but not dazzling, just like a unique light hidden in the ordinary.
In terms of its state, under room temperature, it may be a delicate powder with uniform particles and a soft touch, like fine sand sliding through the fingers, but it is lighter than fine sand; or it is a thick liquid, which seems to have a satin texture in the flow, smooth and coherent.
When it comes to the melting point, its melting point is not very high, just like thin ice in winter. When it encounters a little warmth, it slowly melts and turns into a different form; the boiling point is in a specific range, and at the right temperature, it seems to be able to break free and rise and change.
Solubility is also one of its characteristics. In some organic solvents, it is like a wanderer returning home, can quietly integrate, and blend with the solvent to form a uniform state; in water, it is like oil and water that are difficult to blend, maintaining its own independent state.
Its density is also unique. Compared with common things, it may be light or heavy, and it has its own balance. Placed in a specific container, it can show its unique position according to its own density.
This 1% 2C2-diene-4-isothiocyanate rhodium is rich in physical properties and has potential uses in many fields. Only when people explore it in depth can they understand its wonders.
Is the chemical property of 1,2-difluoro-4-isothiocyanate benzene stable?
The physical properties of 1% 2C2-diene-4-isothiocyanate benzene are still stable. Among this compound, the diene structure endows it with certain conjugate stability, while the existence of isothiocyanate has certain reactivity, but under common conditions, the molecule as a whole can maintain a relatively stable state.
From the structural point of view, the conjugate system makes the electron cloud distribution more uniform, reducing the energy of the molecule, thereby enhancing its stability. Although isothiocyanate contains atoms with different electronegativity such as nitrogen and sulfur, it can undergo nucleophilic and electrophilic reactions, but its reactivity is in a controllable range when there is no specific reagent or condition excitation.
In the general environment, when the temperature and humidity do not reach an extreme level, and there are no strong oxidizing agents or reducing agents, 1% 2C2-diene-4-isothiocyanate benzene can maintain its chemical structure and properties unchanged for a long time. However, in case of a specific chemical environment, such as strong acid, strong base or high temperature and other harsh conditions, its stability may be damaged, and chemical reactions such as addition and substitution occur to change its chemical properties and structure.
Overall, under conventional conditions, the chemical properties of 1% 2C2-diene-4-isothiocyanate benzene are relatively stable, which can provide a relatively stable basis for related chemical research and applications.
What is the preparation method of 1,2-difluoro-4-isothiocyanate benzene?
To prepare 1,2-diene-4-isothiocyanate benzene, the method is as follows:
First take an appropriate amount of benzene, place it in a clean reactor, cool it at low temperature to about -10 ° C to 0 ° C, and slowly add a halogenated reagent containing a specific ratio. The halogenated reagent needs to be prepared in a precise ratio in advance, and it needs to be continuously stirred when adding dropwise to make the reaction uniform. After the halogenation reaction is completed, heat up to room temperature, add an appropriate amount of basic substances, and promote the elimination reaction of halogen atoms to form double bonds to obtain benzene derivatives containing 1,2-diene structures.
Then, transfer the derivative to another reaction vessel and add a specific thiocyanation reagent. The amount of this reagent needs to be accurately calculated according to the amount of the derivative. The reaction temperature is controlled between 40 ° C and 50 ° C. During the reaction, a slight boiling state is maintained, and an inert gas is continuously introduced to protect the reaction system. When the reaction is sufficient, a specific organic solvent is used for extraction and separation to remove impurities, and then through fine operations such as vacuum distillation, a pure 1,2-diene-4-isothiocyanate benzene can be obtained.
In this process, the temperature, reagent dosage, reaction time, etc. of each step need to be strictly controlled. If there is a slight difference, the purity and yield of the product will be affected. Operators also need to be skilled and familiar with the characteristics of various reactions in order to produce qualified products.
What are the precautions for storing and transporting 1,2-difluoro-4-isothiocyanate benzene?
For 1% 2C2-diene-4-isothiocyanate benzene, there are things to pay attention to when hiding and losing it.
When hiding, the environment is the first priority. It is sensitive and should be placed in a cool and dry place, protected from heat and humidity. Heat is easy to promote its transformation, and moisture can also cause quality change. Therefore, it is better to keep the temperature constant at about 2-8 degrees Celsius, so that it can keep its stability and not bad for a long time.
Furthermore, the need to avoid light should not be ignored. Under light exposure, or induced by it, it will damage its quality. The container should be opaque, or stored in a darkroom, to eliminate the source of light.
Also, it must be cautious when coexisting with other things. Do not mix with alkalis, oxidizing agents, etc. These numbers are easy to react with 1% 2C2-diene-4-isothiocyanate benzene, causing it to deteriorate and lose its original use.
As for the loss, the tightness of the package is the most important. Pack it with a solid and tight device to prevent it from leaking out. The shock on the way must also be taken into account when using suitable materials to cushion the shock, so as not to break the device and prevent it from coming out.
And the temperature at the time of delivery should also be controlled. Keep it at an appropriate temperature and do not change it suddenly. The operator should be aware of its properties, and in case of abnormal conditions, it can be dealt with quickly to ensure its safety.
In short, the storage and transportation of 1% 2C2-diene-4-isothiocyanate benzene should be cautious. According to its physical properties, it can be used to prevent small and gradual progress.