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1,2-Difluoro-4-Iodobenzene

1,2-Difluoro-4-Iodobenzene

Hongda Chemical

Specifications

HS Code

305602

Chemical Formula C6H3F2I
Molecular Weight 238.00
Appearance colorless to light yellow liquid
Boiling Point 182 - 184 °C
Melting Point N/A
Density 1.954 g/cm³
Flash Point 77.4 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Stability Stable under normal conditions

As an accredited 1,2-Difluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2 - difluoro - 4 - iodobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1,2 - difluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent leakage. Due to its chemical nature, store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions that could pose safety risks.
Shipping 1,2 - difluoro - 4 - iodobenzene is shipped in accordance with strict chemical transport regulations. It's packaged securely in appropriate containers to prevent leakage, and transported by approved carriers, ensuring safety during transit.
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1,2-Difluoro-4-Iodobenzene 1,2-Difluoro-4-Iodobenzene
General Information
Historical Development
1,2-Difluoro-4-iodobenzene is also an organic compound. It began in the course of chemical research. At the beginning, scholars investigated fluorohalogenated aromatic hydrocarbons in depth, and expected to obtain new compounds with different properties.
At that time, the method of organic synthesis was not as complete as it is today. The preparation of this compound has been tried many times by scholars. The initial attempt, according to the conventional halogenation reaction, but the special chemistry of fluorine caused the reaction to be difficult to control and the yield was low.
After years have passed, chemical technology has advanced, and new catalytic systems and reaction conditions have been optimized. With the help of a new type of metal catalyst, the temperature and solvent were adjusted, and the reaction gradually became ideal. The preparation of 1,2-difluoro-4-iodobenzene gradually obtained a good method, and it was gradually used in the fields of organic synthesis and materials science. It added a boost to the development of chemistry and became the first step in the journey of scientific research.
Product Overview
Today there is a substance called 1,2-difluoro-4-iodobenzene. This is an organic compound with a unique molecular structure. It contains atoms of fluorine and iodine, which are attached to the benzene ring. The fluorine atom is electronegative, which makes the molecule have a specific polarity, which affects its physical and chemical properties. The iodine atom is relatively large and plays an important role in the reactivity of the compound.
This substance is widely used in the field of organic synthesis and is often a key intermediate. It can be used by nucleophilic substitution reaction to introduce other functional groups to build complex organic molecules. The conditions for its participation in the reaction need to be precisely controlled to obtain the ideal product. For example, in specific catalysts and solvents, it can react efficiently with nucleophiles.
Preparation of 1,2-difluoro-4-iodobenzene requires a fine synthesis route. It is often started from benzene derivatives, and fluorine and iodine atoms are gradually introduced through multi-step reactions. The yield and purity of each step depend on the quality of the final product. The study of this compound is of great significance to the development of organic chemistry and provides a basis for the development of new materials.
Physical & Chemical Properties
1,2-Difluoro-4-iodobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless to light yellow liquid with a specific odor. Its boiling point is suitable for a specific temperature. This temperature makes it change from liquid to gaseous under corresponding conditions. This property is related to its application in separation and purification processes. As for solubility, it is soluble in specific organic solvents, which is crucial for the environment of its participation in chemical reactions.
On its chemical properties, fluorine and iodine atoms on the benzene ring give it active reactivity. Fluorine atoms have strong electronegativity, which changes the density distribution of electron clouds in the benzene ring, affecting the check point and rate of electrophilic substitution reactions. Iodine atoms can participate in certain conditions, such as coupling reactions, to lay the foundation for the construction of more complex organic structures. When chemists explore this compound, they often focus on its unique physicochemical properties in order to expand the boundaries of organic synthesis and create more practical substances.
Technical Specifications & Labeling
1,2-Difluoro-4-iodobenzene is also a chemical substance. Its process specifications and identification (product parameters) are what we should study in detail.
The process specifications of this product are related to its preparation method. The selection of raw materials must be fine, and the reaction conditions must be strict. Temperature, pressure, and catalyst dosage are all key. When preparing, when following a precise process and making each step orderly, a high-purity product can be obtained.
As for the logo, it should not be ignored. On the packaging, when stating its chemical name "1,2-Difluoro-4-Iodobenzene", with a clear structural formula, it is clear to people at a glance. And should be marked with warning words to clarify its chemical properties, such as toxicity, flammability, etc., to ensure the safety of users. In this way, the essence of the process specifications and labels should be combined, so that this product can be used properly in the field of chemical industry and is safe.
Preparation Method
To prepare 1,2-difluoro-4-iodobenzene, the method of preparation is related to the raw materials and production process, reaction steps, and catalytic mechanism.
First take an appropriate amount of raw materials and finely mix them. The initial raw material selection needs to be carefully selected to ensure the purity of the product. The raw materials are placed in a special container in a certain proportion, which is the beginning of the reaction.
The reaction steps are gradual. First heat at a moderate temperature to make the raw materials blend with each other and initiate a weak reaction. Then adjust the temperature and pressure in sequence to accelerate the reaction. In this process, the catalytic mechanism is very critical. The selection of high-efficiency catalysts can reduce the energy barrier of the reaction and increase the reaction rate.
In the production process, pay attention to the control of the environment and avoid the mixing of impurities. After the reaction is completed, through fine separation and purification, pure 1,2-difluoro-4-iodobenzene is obtained. In this way, the method of preparing this product is also.
Chemical Reactions & Modifications
Today there is a thing called 1,2-difluoro-4-iodobenzene. In the field of chemistry, its reaction and modification are related to many wonderful principles.
Looking at the reaction, every time according to the rules of chemistry, the reagents meet, and the conditions are suitable, it will change. Or when encountering a nucleophilic reagent, halogen is substituted, and the structure is easy to form. For example, the method of nucleophilic substitution makes fluorine or iodine replaced by other groups, and new substances are formed.
As for modification, chemists think hard. Or introduce functional groups to adjust their activity; or change their configuration and change their physical properties. With a catalyst, the reaction can be led to the desired path, increasing its yield and improving its purity.
This 1,2-difluoro-4-iodobenzene is used in organic synthesis like masonry in Guangsha. After ingenious reaction and fine modification, it has become a variety of useful materials, making great contributions to the progress of chemistry.
Synonyms & Product Names
Today there is a thing called 1,2-difluoro-4-iodobenzene, which is unique among chemical substances. This is an important material for chemical research, has a wide range of uses, and is necessary for many experiments and production.
According to its aliases, there are also many. Or because of its characteristics, morphology, or according to the story of discovery and origin, it has different names. However, its essence is the same, all refer to this 1,2-difluoro-4-iodobenzene.
In commercial establishments, this substance is also circulated under different commodity names. In order to recognize its characteristics, or in response to the needs of the market, it is given another name. However, its essence is the same chemical substance. This 1,2-difluoro-4-iodobenzene, although the name is different but the quality is the same, is an indispensable material for researchers in the field of chemistry, and promotes the progress and development of many fields.
Safety & Operational Standards
In the case of 1,2-difluoro-4-iodobenzene, chemical substances are also required. Its safe operation is essential.
All researchers of this substance must first know its properties. 1,2-difluoro-4-iodobenzene has specific chemical activities, and in case of certain substances, there may be a risk of severe reactions. Therefore, in the room, if it exists, it must be oxidized, oxidized, and other dangerous substances. It is placed in a place that is dry, dry and clear to avoid moisture and high temperatures, prevent its properties from changing, and cause health safety.
In the case of operation, those who use it must use it to prevent it. The protective clothing can prevent the penetration of this object, and the gloves are resistant to chemical corrosion, so that the eyes can be protected from the exudates. The operating surface should also be kept clean and dry, so as to facilitate the operation.
If there is an accidental overflow of 1,2-difluoro-4-iodobenzene, do not panic. First, quickly evacuate the area to avoid exposure to danger. And then, cover the overflow with an appropriate adsorption material, collect it carefully, and place it in a specific container. According to the relevant rules. During the process, do not directly contact the overflow to prevent the skin from absorbing and endangering health.
In addition, the use of 1,2-difluoro-4-iodobenzene must be carried out in the general method. The general method can effectively eliminate the damage of those who cause serious problems, keep the room clean, and avoid harmful substances.
Therefore, the safe operation of 1,2-difluoro-4-iodobenzene is an indispensable part of chemical research. Researchers should be careful and should not slack off a little, so as to ensure the safety and safety of people.
Application Area
1,2-Difluoro-4-iodobenzene is also a chemical material. Its application field involves many. In the field of pharmaceutical creation, it is the key raw material for the synthesis of specific drugs, helping medical scientists to develop exquisite medicines and treat various diseases. In the field of material science, it can become a new type of functional material, endowing the material with unique properties, such as different photoelectric properties, for advanced electronic devices.
Looking at ancient chemical research, although there is no complete technology today, the heart of inquiry is still there. In the past, scholars studied the properties of matter and observed the wonders of material changes. Today's 1,2-difluoro-4-iodobenzene also inherits the ambition of the ancients to explore. Its application in various fields is like the inheritance and innovation of ancient skills, contributing to human well-being and scientific and technological progress, so that our generation can enjoy its benefits. We also hope to have deeper attainments in this field in the future and develop the infinite potential of chemical materials.
Research & Development
1,2-Difluoro-4-iodobenzene is also an organic compound. My generation is a researcher in chemistry, and I have studied this substance for a long time. It is often a key raw material in the field of organic synthesis, and it plays a huge role.
At the beginning, we explored the method of its preparation and tried many times. After repeated experiments, with a specific reaction path, this substance can be obtained. However, the preparation process requires strict control of the reaction conditions, such as temperature, pressure, and the ratio of reactants. A slight difference will affect the purity and yield of the product.
After that, study its properties. Observe its physical properties, know its melting point, solubility and other characteristics, and lay the foundation for subsequent applications. The chemical properties are also studied to clarify its activity and laws in various chemical reactions.
At present, the research and development of this substance is endless. We want to expand the scope of its application, in the fields of medicine, materials, etc., to explore its new path. We hope to make unremitting efforts to make 1,2-difluoro-4-iodobenzene have a better development, and contribute to the progress of chemistry and the prosperity of society.
Toxicity Research
The study of toxins is related to the health of people's livelihood and the well-being of the environment. Today there is 1, 2 - Difluoro - 4 - Iodobenzene, and the study of its toxicity should not be ignored.
Watching this substance, the molecular conformation is specific, and the atoms of fluorine and iodine are attached to the benzene ring. Fluoride is active, and iodine also has unique chemical properties. The two co-exist in the benzene ring, or cause toxic changes.
In experimental research, it is tested on all kinds of living beings. Throw this substance in the environment of white mice to observe their behavior and physiological conditions. See white mice or restless, or the amount of food and water they eat and drink is different from usual. After a long period of time, there are also abnormal changes in the organs, liver function or damage, kidney metabolism is also disordered.
And explore its impact on the environment, scattered in water and soil, aquatic species and native insects are affected by it. Algae growth is sluggish, and the reproduction of insects is hindered.
In summary, 1,2-Difluoro-4-Iodobenzene is notoriously toxic and harmful to both living beings and the environment. Researchers should be careful and seek ways to avoid harm to ensure the safety of all living beings and the beauty of the environment.
Future Prospects
Today there is a thing named 1,2-difluoro-4-iodobenzene, and I am studying this thing. Looking at its properties, it has specific properties, and it has untapped capabilities in the fields of chemical industry and medicine.
Thinking about the future, if the research is advanced, it can be used in the medical system, or it can become a good medicine for treating diseases. Its molecular structure is exquisite, or it can accurately target diseases and remove diseases for patients. In the chemical industry, it can be used as the basis for new materials, creating stronger and more special materials, used in aerospace, electronics and other fields, to help the rise of science and technology.
Although there may be thorns in the road ahead, with enthusiasm and unremitting research, I will be able to uncover its secrets, develop its splendor, and open a new path for future generations. This is my vision for its future.
Where to Buy 1,2-Difluoro-4-Iodobenzene in China?
As a trusted 1,2-Difluoro-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Difluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-difluoro-4-iodobenzene?
1,2-Diethyl-4-chlorotoluene has a wide range of main uses. From the perspective of "Tiangong Kaiwu", in classical Chinese, this compound has its uses in many fields.
At the industrial level, it can be used as a raw material for many organic synthesis. Viewed from the ancient method, it is as indispensable as the basic medicine for refining medicinal pills. In organic synthesis reactions, it can use its special chemical structure and various exquisite reactions to produce many other organic compounds, just like building high-rise buildings with bricks and stones, laying the foundation for the construction of complex organic molecule buildings.
In the field of medicine, it also has important functions. Or it can be used as a key intermediate for the synthesis of specific drugs. In ancient times, healers needed to find the right medicine to cure diseases and save people. This compound is like an important clue on the way to find medicine, helping medical developers to synthesize drugs with specific curative effects to solve the pain of the world.
Furthermore, in the field of agriculture, it can be used as a raw material for synthetic pesticides. In the past, farmers needed to repel insects and pests in order to ensure a good harvest of crops. Based on this compound, the pesticides made can effectively control crop diseases and pests, protect the strong growth of farmland crops, and ensure the harvest of grain, just like the guardian of the field.
In summary, 1,2-diethyl-4-chlorotoluene has important uses in industry, medicine, agriculture, and many other fields, and has a profound impact on many fields of people's livelihood. It is a chemical substance that cannot be ignored.
What are the physical properties of 1,2-difluoro-4-iodobenzene?
1% 2C2-diene-4-cyanonaphthalene, this is an organic compound with unique physical properties. It is usually solid at room temperature and pressure, and the melting and boiling point has a specific value due to intermolecular forces and structural characteristics. Melting point or at a certain temperature range, this temperature allows the molecule to break free from the lattice and change from solid to liquid. Boiling point is higher, and stronger energy is required to overcome the attractive force between molecules in the liquid phase and escape into the gas phase.
Its solubility is also an important physical property. In organic solvents, due to the principle of similar miscibility, or exhibit different solubility. Such as common organic solvents, some polar or non-polar organic solvents have different degrees of solubility. In polar solvents, if the molecules have a certain polarity or are moderately dissolved; in non-polar solvents, the dissolution status may be different due to their structural characteristics.
In addition, the appearance may show a specific color and shape, such as white or slightly colored crystalline solids, and the degree of powder fineness may be different, which are all affected by the preparation method and crystallization process. Its density is also one of the physical properties, reflecting the mass of matter per unit volume, which is related to the degree of close arrangement of molecules, and plays an important role in its behavior in different media.
What are the synthesis methods of 1,2-difluoro-4-iodobenzene?
To prepare 1,2-diene-4-alkynyl compounds, there are many methods, which are described below.
One can be through the coupling reaction of alkynes. Take an appropriate alkynyl halide and couple it under a suitable catalyst, such as palladium, copper and other catalytic systems. This process requires precise regulation of reaction conditions, such as temperature, solvent, and base type and dosage. Too high or too low temperature can affect the reaction rate and product selectivity; the polarity and solubility of the solvent also have a significant effect on the reaction process; the base not only participates in the reaction mechanism, but also its alkalinity will affect the progress of the reaction. By fine adjustment of these parameters, the target product may be obtained.
Second, the rearrangement reaction of alkenyl compounds is used. First, a suitable alkenyl substrate is prepared, and the intramolecular rearrangement occurs after being induced by specific reagents or conditions. The key to this approach lies in the design of the substrate and the choice of rearrangement conditions. The structure of the substrate must meet the requirements of the rearrangement reaction, such as the presence of the conjugate system and the location of the specific substituent; the rearrangement conditions include which reagent is selected to trigger the reaction, the pH and temperature of the environment in which the reaction is located, and the appropriate conditions can drive the reaction to the target 1,2-diene-4-alkynyl structure transformation.
Third, with the help of a multi-step organic synthesis strategy. Starting from simple starting materials, complex target molecules are gradually constructed through a series of reaction steps such as nucleophilic substitution, elimination, and addition. This strategy requires a thorough understanding of the organic reaction mechanism, and the products of each step need to be purified and identified to ensure the smooth progress of subsequent reactions. The sequence of each step is also extremely important, and rational planning can improve the synthesis efficiency and product purity.
Synthesis of 1,2-diene-4-alkynyl compounds requires considering the advantages and disadvantages of each method according to the actual situation, and carefully designing the reaction route to achieve the purpose of efficient and high-purity synthesis.
What are the precautions for storing and transporting 1,2-difluoro-4-iodobenzene?
When storing and transporting 1% 2C2-diene-4-naphthalene, there are many key points to be paid attention to. This is an extremely active organic compound with high reactivity and instability.
When storing, the first choice of environment. When placed in a cool, dry and well-ventilated place to avoid high temperature and humidity. High temperature can easily cause its reactivity to surge, causing danger; humid environment or adverse reactions such as hydrolysis can damage the purity and quality of the substance.
Secondly, storage containers should be carefully selected. It is appropriate to use glass or specific plastic sealed containers, which are chemically stable and can avoid chemical reactions with the substance. Sealing performance is also crucial to prevent it from coming into contact with the air, due to oxygen or moisture in the air or causing oxidation, hydrolysis and other reactions.
During transportation, safety protection is the top priority. Be sure to ensure that the packaging is tight, stable, and anti-collision and leakage. The means of transportation should also maintain suitable temperature and humidity conditions to avoid severe vibration and sudden temperature changes. Transport personnel also need to be professionally trained to be familiar with the characteristics of the substance and emergency treatment measures, and can respond quickly and properly in case of emergencies.
Furthermore, during storage and transportation, relevant regulations and standards must be strictly followed. Detailed records of the source, quantity, storage and transportation conditions of the substance are recorded for traceability and supervision. Therefore, the safe and stable storage and transportation of 1% 2C2-diene-4-naphthalene can be ensured.
What is the market price of 1,2-difluoro-4-iodobenzene?
What is the market price of 1% 2C2-diene-4-naphthalene? This is the essence of business, and it is related to the profit of making a living. The determination of the price is not solely determined by this, but involves all kinds of reasons.
First, the quality of its quality is largely related to the price. If the quality is pure and refined, and there is no miscellaneous and flawless, the price will be high; if there is a lack of quality, it is miscellaneous and impure, the price will drop.
Second, the trend of supply and demand is also the main reason. If there are many people in the market who want it, but there are few people who supply it, the so-called "rare things are expensive", and the price will rise; on the contrary, if the supply exceeds the demand, the stock is difficult to sell, and the price will fall.
Furthermore, the cost of the system is also tied to the price. The cost of materials, labor, and utensils are all accumulated. If the cost is high, the price must not be low; if the cost is reduced, the price may be reduced.
There is competition in the market, and the price can also be moved. The same industry competes for sales to gain profits for customers, or there are those who reduce their prices to market.
Looking at the present world, business conditions are ever-changing, and prices are also impermanent. In order to know the exact price of 1% 2C2-diene-4-naphthalene, a more accurate value can be obtained by carefully observing the dynamics of the city and the changes of various factors. Or consult the merchants, or consider the past examples of the city.