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1,2-Difluoro-3-(Trifluoromethyl)Benzene

1,2-Difluoro-3-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    470769

    Chemical Formula C7H3F5
    Molecular Weight 182.09
    Appearance Colorless liquid
    Boiling Point 107 - 109 °C
    Melting Point N/A
    Density 1.39 g/cm³
    Flash Point 15 °C
    Solubility In Water Insoluble
    Vapor Pressure N/A
    Odor Characteristic aromatic odor

    As an accredited 1,2-Difluoro-3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2 - difluoro - 3 - (trifluoromethyl)benzene in 5 - liter containers for chemical packaging.
    Storage 1,2 - difluoro - 3 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat sources and ignition sources. It should be kept in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential reactions. Use suitable storage cabinets or areas designated for hazardous chemicals.
    Shipping 1,2 - difluoro - 3 - (trifluoromethyl)benzene, a chemical, should be shipped in well - sealed, corrosion - resistant containers. Ensure compliance with hazardous materials regulations, with proper labeling for safe transportation.
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    1,2-Difluoro-3-(Trifluoromethyl)Benzene 1,2-Difluoro-3-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1,2-Difluoro-3- (trifluoromethyl) benzene is also an organic compound. Although the beginning of its product is difficult to be studied in ancient times, modern chemistry is flourishing, and many wise people are pursuing it more and more.
    In the past, chemists focused on the wonders of elemental synthesis, and in the field of halogenated aromatics, they gradually gained something. The first wise people paid attention to fluorobenzene, and after years of research, experiments were complicated, and formulas were easy, they finally obtained this 1,2-difluoro-3- (trifluoromethyl) benzene.
    At the beginning, it was difficult to prepare, and the yield was quite low. Only a small amount was occasionally obtained in the laboratory. After learning, improve the techniques and optimize the process, so that the preparation of this material gradually matures and the application gradually widens. From the initial theoretical inquiry, it was later used in medicine and materials industries. In the process of chemical history, it was like a pearl gradually appearing, promoting the chemical industry to move forward step by step, with far-reaching impact, and was the foundation of future scientific research and industry.
    Product Overview
    1,2-Difluoro-3- (trifluoromethyl) benzene is also an organic compound. Its shape is a colorless liquid with a special odor. This compound contains a large number of fluorine atoms, resulting in its unique physical and chemical properties.
    In terms of physical properties, its boiling point and melting point are different from common benzene series. Due to the high electronegativity of fluorine atoms, the intermolecular force is in a different state, and the boiling point is appropriate, which is convenient for separation and application.
    In terms of its chemical properties, due to the electron-absorbing effect of fluorine atoms, the electron cloud density of the benzene ring changes, making its reactivity different from that of benzene. During the electrophilic substitution reaction, the entry position of the substituent is affected by the distribution of fluorine atoms. And because it contains polyfluoride, it has good chemical stability and thermal stability.
    In the field of industry and scientific research, 1,2-difluoro-3- (trifluoromethyl) benzene is widely used. It can be used as an intermediary for the synthesis of medicine and pesticides. With its special structure, it can introduce specific functional groups to make special drugs and pesticides. In material science, it can also be used as a raw material for the synthesis of special polymer materials, giving materials unique properties.
    Physical & Chemical Properties
    The physicochemical properties of 1,2-difluoro-3- (trifluoromethyl) benzene are particularly important. Looking at its physical properties, at room temperature, it is colorless and transparent, like water, with a unique smell and a slightly pungent feeling. Its boiling point is moderate, about a specific value, which is convenient for separation and purification. In terms of chemical properties, this benzene compound has a unique reactivity due to the presence of fluorine and trifluoromethyl. The strong electronegativity of fluorine atoms causes the density of its adjacent and para-position electron clouds to decrease, and it presents a unique selectivity in electrophilic substitution reactions. And trifluoromethyl is a strong electron-absorbing group, which further affects its chemical activity, making it a key raw material in many organic synthesis reactions, and can derive many valuable products. It is of great significance in the research and application of organic chemistry.
    Technical Specifications & Labeling
    Today there is a product named 1,2-difluoro-3- (trifluoromethyl) benzene. Its technical specifications and identification (commodity parameters) are the key to our research. Looking at this substance, it is necessary to clarify its physical and chemical properties. As far as specifications are concerned, its purity should reach a very high level, and impurities need to be minimal before it can be used.
    On the label, the name should be detailed, the label should be accurate, and the molecular formula and structural formula should also be clearly presented. And it is necessary to warn it of possible dangers, such as toxicity, explosive properties, etc. In its commodity parameters, melting point, boiling point, density and other data are all key, and accurate determination can only be used. This technical specification and logo are related to the quality and application of this object, and we should treat it with caution and avoid any mistakes in order to achieve the best.
    Preparation Method
    The method of making 1,2-difluoro-3- (trifluoromethyl) benzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are selected from suitable halogenated aromatics and fluorine-containing reagents, which are related to the reaction process. The production process is controlled by precise temperature and pressure in a special reactor. First, the halogenated aromatics are mixed with fluorine-containing reagents, and a specific catalyst is used. The catalytic mechanism is that the catalyst promotes the fracture and recombination of the bonds between the two. The reaction steps gradually progress at the beginning, and they are closely observed. After the reaction is completed, the impurities are removed through the purification process to obtain pure 1,2-difluoro-3- (trifluoromethyl) benzene. In this way, the production method and the precise control of each link can effectively produce this chemical.
    Chemical Reactions & Modifications
    There is now a product named 1,2-difluoro-3- (trifluoromethyl) benzene. In the field of chemistry, we investigate its reaction and modification, which is a priority.
    Looking at the reaction, it encounters various reagents, or changes in substitution, or additions. Its structure is unique, and the position of fluorine and trifluoromethyl affects the reaction path. In case of electrophilic reagents, because of the electron-withdrawing property of fluorine atoms, the electron cloud density of the benzene ring changes, and the reaction check point is different from that of benzene.
    As for modification, other groups can be introduced to change their properties. Or increase its stability, or change its solubility to suit different needs. This substance has potential uses in the fields of materials and medicine. Therefore, studying its reaction and modification can open up a new path for the development of chemistry, benefit human life, and promote the progress of science and technology.
    Synonyms & Product Names
    1,2-Difluoro-3- (trifluoromethyl) benzene, this substance is of great significance in our chemical research. Looking at its synonyms, there are many titles, all of which are recognized by the academic community and are the basis for research and communication. And the trade name also carries a specific commercial representation, which is identified by the market place.
    The synonyms of husband are common in the academic world, so that although researchers are in different places, they can also understand what they mean. Either from the analysis of the structure, or because of the relationship between the properties, there are different titles, all of which are accurate descriptions of the characteristics of this object. As for the trade name, the merchant decides after careful consideration in order to recognize its characteristics and be different from others.
    1,2-difluoro-3- (trifluoromethyl) benzene, with its unique chemical structure, has emerged in many fields. The clarity of synonyms and trade names helps us to better study and apply this substance, open up new frontiers in the chemical world, and contribute to academic and industrial progress.
    Safety & Operational Standards
    Specifications for the safety and operation of 1,2-difluoro-3- (trifluoromethyl) benzene
    Wife 1,2-difluoro-3- (trifluoromethyl) benzene is an important substance in chemical research. In its experimental operation and use, safety is the first priority and norms must be followed.
    Looking at its physical properties, this substance has a specific state, taste and volatility. In the laboratory environment, it should always be paid attention to its diffusion to prevent it from affecting the air quality and endangering the health of the researcher.
    When operating, protective equipment is indispensable. It is recommended to wear special protective clothing, which can resist the possible erosion of the substance; wear protective gloves, the material should be able to effectively block and avoid contact with the skin. Face protection should not be ignored, and goggles should prevent it from splashing into the eyes.
    When taking it, you must follow the precise measuring device and steps. Check the required dose first, and take it with a suitable pipette or measuring cylinder. The action should be stable and accurate to avoid its spilling. If there is any spilling, dispose of it immediately according to the specifications, and do not let it go.
    When storing, choose a suitable container. This substance should be stored in a sealed, corrosion-resistant device, in a cool, dry and well-ventilated place, away from fire sources and oxidants, to prevent unexpected reactions.
    During the experiment, the ventilation system must be smooth. If it is operated in the fume hood, ensure its normal operation and allow the harmful gases to be discharged in time. At the same time, the temperature, pressure and other conditions of the reaction should be closely monitored and regulated according to the established procedures, and cannot be changed without authorization.
    If it is inadvertently touched, regardless of the skin or eyes, quickly rinse with a lot of water, and then according to the severity of the injury, seek professional medical help.
    In summary, in the research and application of 1,2-difluoro-3- (trifluoromethyl) benzene, strictly abide by the safety and operation standards to ensure the smooth experiment and the safety of personnel.
    Application Area
    1,2-Difluoro-3- (trifluoromethyl) benzene, this compound has a wide range of application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new specific drugs with unique curative effects for specific diseases. In the field of materials science, it can be used to prepare functional materials with special properties, such as high-performance optical materials or electronic materials, so that the materials have excellent stability and unique optical and electrical characteristics. And in the field of fine chemicals, it is also an important raw material for synthesizing high-end fine chemicals, improving product quality and performance, and is widely used in many high-end manufacturing and scientific research scenarios to promote the development and innovation of related fields, which is of great significance to the progress of various industries.
    Research & Development
    In recent years, I have been researching many chemical things, especially the product of 1,2-Difluoro-3- (Trifluoromethyl) Benzene. Its unique nature has potential in various fields, so I have devoted my efforts to studying it.
    At the beginning, I used the method of its preparation to visit various classics and try various paths. Or adjust the temperature, or change the agent, to achieve purity. Although the process is difficult, but the direction of the heart is endless.
    After obtaining it, re-study its properties. Observe its response to other things and measure its physical characteristics. Knowing its application in the field of chemical industry and medicine may be a new way.
    Looking to the future, I hope this product will be widely used. In time, if I can use it to create a good medicine or help the progress of the chemical industry, I will be fortunate to explore it. Unremitting in research, I have achieved success in the period, and I will do my best for the prosperity of chemistry.
    Toxicity Research
    Today, there is a product named 1,2-difluoro-3- (trifluoromethyl) benzene, which is common in our chemical research. The investigation of its toxicity is crucial.
    The toxicity of this product is related to the safety of living beings and environmental changes. Looking at the past, all kinds of poisons have caused disasters in the world. Or harm the lives of living beings, or upset the ecological balance. 1,2-difluoro-3- (trifluoromethyl) benzene, although it has not been seen in the public, its potential danger cannot be ignored.
    We should explore the depth of its toxicity with a rigorous heart. Observe its interaction with biological bodies, and study the influence of cells and molecules. It is also necessary to investigate the rules of migration and transformation in the environment in detail to prevent it from being invisible and causing great trouble. In this way, we can protect all things in the world, be quiet and orderly, and do not let poisons ravage and harm the common people.
    Future Prospects
    Today there is a product named 1,2-difluoro-3- (trifluoromethyl) benzene. Our generation of chemical researchers are looking forward to its future and have expectations.
    This material property is unique and can be used in various fields. Looking at today's technology, materials are seeking new quality. It may be used in the production of high-end materials. With its uniqueness, the material has excellent properties, such as toughness and corrosion resistance. It must be of great use in aviation and electronics.
    There is also dawn in the road of medicine. It may be a research foundation for new drugs, with its structure, to explore ways to fight diseases and solve the suffering of everyone.
    Although the road ahead is uncertain, I firmly believe that with time, all researchers will work together to understand its potential and develop its talents. In the future, this thing should be widely used to advance the world, contribute to the prosperity of all industries, and benefit all people.
    Where to Buy 1,2-Difluoro-3-(Trifluoromethyl)Benzene in China?
    As a trusted 1,2-Difluoro-3-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,2-Difluoro-3-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,2-difluoro-3- (trifluoromethyl) benzene?
    1% 2C2-diene-3- (trienyl methyl) benzene-based organic compounds have various main uses and are of great value in many fields.
    In the field of organic synthesis, this compound is a key intermediate. Due to its rich conjugated dienes and benzene ring structure in its molecular structure, it has high chemical activity and can generate cyclic compounds with diverse structures through many organic reactions, such as the Diels-Alder reaction. This reaction is a classic method for constructing complex carbon ring skeletons and is widely used in total synthesis of natural products and drug synthesis. With this compound participating in the Diels-Alder reaction, cyclic intermediates with specific structures can be easily synthesized, laying the foundation for the subsequent synthesis of complex natural products or pharmaceutically active molecules.
    In the field of materials science, its conjugated structure endows materials with unique optical and electrical properties. It can be used as a raw material for the preparation of organic optoelectronic materials, such as organic Light Emitting Diode (OLED) materials. The conjugated system is conducive to electron delocalization. When excited by light or an electric field is applied, the electron transition can produce fluorescence or phosphorescent, thereby realizing the luminescent function, which is expected to improve the luminous efficiency and color purity of OLED devices. In addition, in organic solar cell materials, the conjugated structure of the compound can promote the generation and transmission of photogenerated carriers, and improve the photoelectric conversion efficiency of the battery.
    In the field of pharmaceutical chemistry, the phenyl ring and alkenyl structure provide rich modification check points for drug molecular design. By introducing different substituents, the molecular physicochemical properties and biological activities can be adjusted, which is in line with drug R & D requirements. Studies have shown that some derivatives modified by this compound as the parent show certain inhibitory or regulatory effects on specific disease targets, providing direction for the development of new drugs.
    In summary, 1% 2C2-diene-3- (trienomethyl) benzene is widely used in the fields of organic synthesis, materials science and medicinal chemistry, which is of great significance to promote the development of related fields.
    What are the physical properties of 1,2-difluoro-3- (trifluoromethyl) benzene?
    1% 2C2-diene-3- (trienomethyl) benzene is a chemical compound, and its physical properties are very special. Today, it is said in ancient Chinese.
    The color of this compound is often transparent in color, such as the clarity of a clear spring, and the dyeing of it. Its taste is slightly fragrant, but it is not rich and resistant. It is just like a secluded place, which is smooth and light.
    And the degree of melting and boiling, the melting time is low, under normal temperature, or in the form of liquid flow. If it is slightly cold, it begins to solidify, just like water meets condensation and ice. Its boiling time is also not high, the degree of heating is increased, and the steaming time is high.
    In terms of density, the water is slightly smaller. If this liquid is in water, it floats on the water surface, just like oil floats in water, and the boundary is clear. Its solubility is also special, and it can be well miscible in soluble water, such as ethanol and ether. It is like water emulsifying, and it is a natural one. However, in water, it dissolves, just like a stone entering water, and sinks to the bottom without melting.
    Furthermore, the property of this object is low, and it is open in the air, and it will not last for a long time. It will dissipate when exposed to light in the morning dew. And its refractive index also has a specific value. Light can pass through the body, and the refraction of the body is a law, so this can be done.
    Therefore, the physical rationality of 1% 2C2-diene-3- (trienomethyl) benzene is an important factor in chemical exploration and general industrial application, and it can be used to make the world a better place.
    Is the chemical property of 1,2-difluoro-3- (trifluoromethyl) benzene stable?
    1% 2C2-diethyl-3- (triethylmethyl) naphthalene This compound is relatively stable in nature. Its stability is due to various structural factors. From the perspective of naphthalene ring structure, naphthalene is fused from two benzene rings and has aromatic properties. The aromatic system has a highly delocalized π electron cloud, which can disperse the energy of the system and allow the molecule to reach a more stable state. Therefore, the naphthalene ring, as the core structure of this compound, lays the foundation for its stability.
    Side chain part, 1,2-diethyl and 3- (triethylmethyl) groups, alkyl groups have a donor electron induction effect. When these alkyl groups are connected to the naphthalene ring, they can provide electrons to the naphthalene ring through the induction effect, enhancing the electron cloud density of the naphthal The increase of electron cloud density can make the naphthalene ring more resistant to the attack of electrophilic reagents, thereby improving the stability of the whole compound.
    Furthermore, the molecular spatial structure also affects the stability. Each substituent is distributed in space, forming a certain steric barrier. A larger steric barrier can prevent other molecules from approaching the reaction check point, reduce the possibility of reaction, and further stabilize the compound.
    However, although this compound has high stability, it will still react under certain conditions. For example, under extreme conditions such as strong oxidants, strong acids, and high temperatures, the aromaticity of the naphthalene ring may be destroyed, and side chains may also undergo reactions such as oxidation and substitution. However, under normal mild conditions, 1% 2C2-diethyl-3- (triethylmethyl) naphthalene can maintain a relatively stable state.
    What are the synthesis methods of 1,2-difluoro-3- (trifluoromethyl) benzene?
    The synthesis method of 1% 2C2-diene-3- (trienomethyl) benzene often involves various paths, which are described in detail below.
    First, it can be formed by electrophilic substitution reaction. With benzene as the starting material, appropriate substituents are introduced first to activate or locate the benzene ring. For example, benzene and halogenated hydrocarbons are catalyzed by Lewis acid under Fu-g alkylation reaction to introduce alkyl groups. After that, through a series of reactions such as halogenation and elimination, double bonds are formed at specific positions to gradually achieve the structure of 1% 2C2-diene-3- (trienomethyl) benzene. This path condition is relatively mild, and the raw materials are easy to obtain. However, the steps may be more complicated, and the reaction conditions and the separation and purification of the intermediates need to be carefully controlled.
    Second, the metal-organic chemical method is used. The organic metal reagent is reacted with halogenated aromatics or alkenyl halides to realize the construction of carbon-carbon bonds. For example, palladium-catalyzed cross-coupling reactions, such as Suzuki coupling, Stille coupling, etc. The alkenyl-containing borate ester or tin reagent can be reacted with halogenated benzene derivatives under the action of palladium catalyst and base to form a carbon-carbon double bond with high selectivity and few side reactions, which can effectively synthesize the target product. However, the cost of metal catalysts is higher, and the requirements for reaction equipment and operation are also strict.
    Third, it is synthesized by pericyclic reaction. For example, the Diels-Alder reaction reacts with conjugated dienes and dienophiles, and a six-membered ring structure can be constructed in one step, and a double bond can be introduced at the same time. If the appropriate conjugated dienes and dienophiles with appropriate substituents are selected, after the Diels-Alder reaction, the subsequent modification may be carried out, or 1% 2C2-diene-3- (trienylmethyl) benzene can be efficiently obtained. This method has high atomic economy and simple steps, but it requires harsh structure of the reactants, and requires the preparation of dienes and dienophiles with specific structures in advance.
    What should be paid attention to when storing and transporting 1,2-difluoro-3- (trifluoromethyl) benzene?
    1% 2C2-diene-3- (trienomethyl) naphthalene should be stored and transported with caution.
    When hiding, place the first importance on it. It is advisable to choose a cool and dry place to avoid all heat sources and open flames, because it is flammable. It should also be kept away from strong oxidizing agents, strong acids and alkalis, etc., to prevent their accidental formation. The reservoir should also be strictly selected, and it must be well airtight to prevent it from leaking outside. And there should be a clear warning mark in the storage place to make everyone aware of its danger.
    When shipping, the device used must be strong and sealed to ensure that there is no leakage on the way. The escort must know the nature of this thing and understand the emergency method. When driving, drive slowly and steadily to avoid sudden brakes and sharp shocks, so as not to damage the device and discharge the material. If you pass through a densely populated place, you need to pay more attention, and choose the right way to go. And whether the regular inspection device is complete on the way, if there is any leakage, deal with it quickly.
    Where 1% 2C2-diene-3- (trienyl methyl) naphthalene is stored and transported, it is necessary to take safety and follow all regulations, so that the disaster can be avoided in the future, and the integrity of people's wealth and the peace of the environment can be preserved.