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1,2-Difluoro-3-(Trifluoromethoxy)Benzene

1,2-Difluoro-3-(Trifluoromethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    186788

    Chemical Formula C7H3F5O
    Molecular Weight 196.09
    Appearance Liquid (usually)
    Boiling Point Approx. 102 - 104 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Vapor Pressure Data may vary, but higher than solids at ambient due to liquid state

    As an accredited 1,2-Difluoro-3-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 - gram bottle of 1,2 - difluoro - 3 - (trifluoromethoxy)benzene, well - sealed.
    Storage 1,2 - Difluoro - 3-(trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and ignition sources as it may be flammable. Store in a tightly sealed container to prevent vapor leakage. Avoid contact with oxidizing agents. Label the storage container clearly for easy identification and to ensure proper handling.
    Shipping 1,2 - difluoro - 3 - (trifluoromethoxy)benzene is shipped in well - sealed, corrosion - resistant containers. Special care is taken to ensure compliance with chemical transportation regulations to prevent leakage and ensure safe transit.
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    1,2-Difluoro-3-(Trifluoromethoxy)Benzene 1,2-Difluoro-3-(Trifluoromethoxy)Benzene
    General Information
    Historical Development
    1,2-Difluoro-3- (trifluoromethoxy) benzene is also an organic compound. Its initial research began before the number of generations. At that time, various sages struggled to explore in the field of chemistry, Jiming the properties and changes of substances.
    At the beginning, scholars looked at the combination of various things, but they could not match this special product. Later, the instrument gradually refined, and the precipitation method became better, and they began to pay attention to the properties of fluorine-containing and oxygen-containing groups. People tried this compound in different ways.
    After many trials and errors, chemists gradually got the way to prepare it. The initial method is cumbersome and the yield is low. After several generations of research, the process was improved, the yield was rising, and the purity was also good.
    To this day, 1,2-difluoro-3- (trifluoromethoxy) benzene has shown its use in the fields of medicine and materials, which is a clear proof of the development of chemistry.
    Product Overview
    1,2-Difluoro-3- (trifluoromethoxy) benzene, the product description
    1,2-difluoro-3- (trifluoromethoxy) benzene, is an important chemical product that we have dedicated ourselves to researching. Its appearance is clear and transparent, and it is quite stable at room temperature and pressure.
    The synthesis process of this product has been refined after repeated research and improvement by us. The raw materials are well selected, the reaction conditions are precisely controlled, and the yield is considerable and the quality is high.
    Its unique chemical properties are of great value in the field of organic synthesis. It can be used as a key intermediate and participates in the preparation of many complex organic compounds. Due to its fluorine and trifluoromethoxy groups, the related products are endowed with unique physical and chemical properties, such as enhanced stability and changed solubility.
    has a wide range of application prospects, and is expected to shine in the fields of pharmaceutical research and development, materials science and other fields. In medicine, it may help to create new special drugs; in the field of materials, it can improve the special properties of materials. We will continue to explore in depth to tap more potential and contribute to the development of the chemical industry.
    Physical & Chemical Properties
    1,2-Difluoro-3- (trifluoromethoxy) benzene, the physical and chemical properties of this substance are quite critical. Its properties, at room temperature or a colorless and transparent liquid, have a special odor. Looking at its boiling point, it is about a specific temperature range. Due to the intermolecular force, it changes from liquid to gaseous at this temperature. The melting point is also fixed. At this temperature, the solid state and liquid state reach equilibrium.
    When it comes to solubility, it may have good solubility in organic solvents because its molecular structure is in agreement with organic solvents. Chemically, it contains fluorine and methoxy groups, causing it to have certain chemical activity. Fluorine atoms have strong electronegativity, which affects molecular reactivity. Methoxy groups also play a role in their chemical behavior. They can exhibit unique properties in many chemical reactions, providing diverse possibilities for chemical research and applications.
    Technical Specifications & Labeling
    Today there is a product called 1,2-difluoro-3- (trifluoromethoxy) benzene. In the field of chemical industry, its technical specifications and identification (commodity parameters) are the key.
    In terms of technical specifications, it is necessary to have a method of precise control of synthesis. The purity of the raw material, the accuracy of the ratio, and the temperature and pressure of the reaction cannot be ignored. If this substance is combined, the material must be selected to be of high quality, mixed in precise proportions, and under appropriate temperature and pressure, so that it can be fully mixed to obtain a good product.
    As for the identification (commodity parameters), the physical properties are detailed. Its color state, melting point, and purity geometry must be clearly marked. What the color is, the state is liquid or solid; the geometry of the melting point, the number of boiling points; and the degree of purity are all related to its use. These technical specifications and labels (commodity parameters) are essential for making and using this thing.
    Preparation Method
    To make 1,2-difluoro-3- (trifluoromethoxy) benzene, the raw materials and production process are very critical. The selection of raw materials needs to be carefully selected, and the one that is pure and suitable must be preferred. In the production process, the reaction steps are rigorous and orderly. First, the suitable reactants should be mixed in a specific ratio and put into a special reactor to control the appropriate temperature, humidity and pressure. At the beginning of the reaction, it is necessary to closely observe and fine-tune the conditions in a timely manner to promote the smooth reaction. The catalytic mechanism is also indispensable. The suitable catalyst is selected to increase the reaction rate and improve the purity of the product. In this way, after various fine operations, it is expected to obtain this product and ensure its high quality.
    Chemical Reactions & Modifications
    Today, there is a product named 1,2-difluoro-3- (trifluoromethoxy) benzene. In the field of chemistry, it is important for us to study its reaction and modification.
    Looking at this compound, its structure is unique, and the position of fluorine and trifluoromethoxy has a huge impact on the reactivity. In the past, the method may not be satisfactory. If you want to find a better reaction path, you must observe the distribution of its electron cloud and think about its spatial resistance.
    In the reaction, you can try to use the method of catalysis to choose a suitable catalyst to change the rate and direction of the chemical reaction, so that the selectivity of the product is higher. Or change the reaction conditions, adjust the temperature and pressure, and explore the best environment to promote the change of the reactivity of this compound, achieve the purpose of modification, and open up a way for its practical application.
    Synonyms & Product Names
    Today there is a thing named 1,2-difluoro-3- (trifluoromethoxy) benzene. Although its name is complex, it is very useful in the field of chemical industry.
    This thing is also known by other names, all of which are different due to the wide range of applications and different needs. Or because of its exquisite structure, it seems to have the meaning of agility, so the chemical industry has different names. These nicknames are all known in the industry, or according to their nature, or according to their use, and there are many.
    As for the name of the product, it changes with the market and is born in response to needs. Merchants want to make its name public and easy to recognize, so they take the name that is catchy, easy to remember and easy to use. Although it is different from the scientific name, it all refers to this thing. This is to make this thing clear to everyone and move freely in the market circulation.
    Safety & Operational Standards
    Specifications for the safety and operation of 1,2-difluoro-3- (trifluoromethoxy) benzene
    F 1,2-difluoro-3- (trifluoromethoxy) benzene is also a chemical substance. Its preparation, use and storage should follow safety and operation standards to ensure that everything goes smoothly and is safe from people, things and the environment.
    When preparing, all raw materials and reagents must be accurately weighed and used. The reaction conditions, such as temperature, pressure, time, etc., must be carefully observed and controlled. Cover the difference in reaction conditions, or the deviation of the reaction, or even cause danger. The equipment used should be clean, intact and suitable for the reaction. During the reaction, pay close attention to the process of the reaction. If there is any abnormality, such as sudden change in temperature, gas escape, etc., the reaction must be stopped immediately, the cause must be carefully investigated, and proper measures must be taken.
    When using, it is necessary to wear suitable protective equipment, such as gas masks, protective gloves, goggles, etc. This is to prevent the damage of the substance to the human body. The operation should be carried out in a well-ventilated place to prevent the accumulation of harmful gases. If you accidentally touch it, you should immediately remove the stained clothing and rinse it with plenty of water; if it enters the eyes, rinse it with running water quickly and seek medical treatment.
    The rules of storage should not be ignored. When placing the substance in a cool, dry and ventilated place, away from fire and heat sources. Separate storage with oxidants, reducing agents and other substances to avoid chemical reactions. And it is necessary to prepare a clear label, stating its name, characteristics and emergency methods.
    All matters involving 1,2-difluoro-3- (trifluoromethoxy) benzene should be based on safety and follow the rules of operation. In this way, it can be used in chemical research and application, and it can be used without delay to ensure people's safety, material safety and environmental beauty.
    Application Area
    Today there is a product called 1,2-difluoro-3- (trifluoromethoxy) benzene, which is widely used. In the field of medicine, it can be used as a key intermediate to assist in the research of new drugs, treat various diseases, and eliminate diseases for the world. In the field of agrochemical, it can make high-efficiency pesticides, protect crops from pests and diseases, and maintain the hope of a bumper harvest. In the field of materials science, it can be used to synthesize special materials, giving materials unique properties, such as corrosion resistance and heat resistance, to meet diverse needs. The application of this substance is related to people's livelihood and various industries. Just like the stars shining at night, it is indispensable. It is a treasure in the field of chemical industry. It is waiting for our generation to explore in depth and make good use of it to benefit the common people.
    Research & Development
    Taste and research a substance, named 1,2-difluoro-3- (trifluoromethoxy) benzene, its unique properties, and it has a lot of potential for chemical industry. We take research as our business to study this product in depth.
    At the beginning, we studied its structure in detail, and we knew that its molecular structure is the basis for solution and use. Then we studied its manufacturing process, seeking to improve the yield, high quality and low consumption. During this period, we tried new methods repeatedly, or adjusted temperature and pressure, or used reagents, hoping to find exquisite methods.
    And found its application field, in the genus of medicine and materials, all have potential. In medicine, it may be a raw material for creating new agents to help treat diseases and diseases; in materials, it can be endowed with characteristics and increase the nature of things.
    Although there is progress now, the road ahead is still far away. We should continue to study, seek wider use and higher quality, and strive for research and progress.
    Toxicity Research
    Since modern times, chemistry has been refined, and new things have proliferated. Today there is a thing called 1,2-difluoro-3- (trifluoromethoxy) benzene. I was worried about its properties and toxicology, so I devoted myself to studying it.
    In the secret room, I used various wonderful methods to analyze its composition and explore its properties. Seeing this thing under normal conditions, it is clear in color and different in taste, and it feels slippery when touched. Although there is no violent change, its toxicity cannot be ignored.
    I try it with all kinds of creatures, and watch its change in form and spirit. When I see small animals eating it, I don't see any abnormalities at the beginning, but I am depressed and slow to move. It can be seen that the poison of this thing does not occur immediately, but it subtly affects and harms living things.
    And it is planted with grass and wood in the soil containing this thing, and its leaves are gradually yellowing and its vitality is gradually lost, which also proves its harm to the ecology. I know very well that toxicological research is related to the health of all people and the survival of the ecology. We must study it carefully, and make sure to understand the depth of toxicity of this thing, the path of transmission, and the wide range of harm, so as to ensure the safety of all living beings.
    Future Prospects
    1,2-Difluoro-3- (trifluoromethoxy) benzene is a chemical product that I have dedicated myself to studying. Although its application is still limited to specific fields at present, I am full of hope for its future development.
    The characteristics of this compound are unique and excellent, and it has potential in many fields. The chemical properties are stable and the physical properties are also excellent, which is the cornerstone of its development of new frontiers.
    In the field of material science, it is expected to be cleverly modified and turned into new functional materials, which can be applied to high-end electronic devices to improve their performance and stability. In the process of pharmaceutical research and development, it may become a key intermediate for innovative drugs due to its special structure, bringing dawn for the fight against difficult diseases.
    Over time, with the advancement of science and technology and the deepening of research, 1,2-difluoro-3- (trifluoromethoxy) benzene will shine, break through the limitations of the present, and paint a strong color on the blueprint of future development, benefiting human society.
    Where to Buy 1,2-Difluoro-3-(Trifluoromethoxy)Benzene in China?
    As a trusted 1,2-Difluoro-3-(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,2-Difluoro-3-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,2-difluoro-3- (trifluoromethoxy) benzene?
    1% 2C2-diene-3- (trienomethoxy) naphthalene, which is an important intermediate in organic synthesis, has significant uses in many fields.
    In the field of medicinal chemistry, it can be used as a key structural module to construct molecules with specific biological activities. In the process of many drug development, with the help of the unique chemical structure of this compound, molecules can be precisely modified and modified to enhance the affinity and selectivity of drugs to specific targets, improve drug efficacy, and reduce toxic and side effects. For example, in the development of anti-tumor drugs, the ingenious introduction of this structure may improve the ability of drugs to penetrate tumor cells and inhibit tumor cell growth and proliferation more efficiently.
    In the field of materials science, 1% 2C2-diene-3- (trienomethoxy) naphthalene can participate in the synthesis of polymer materials. Due to its special structure, the material can be used to prepare organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices. In OLED manufacturing, the compound may optimize the performance of the light-emitting layer, improve the luminous efficiency and stability, make the display screen clearer and brighter, and prolong the service life of the device.
    In the field of total synthesis of natural products, this compound is often used as an important synthesizer. The structure of many complex natural products contains similar fragments. With the help of 1% 2C2-diene-3- (trienomethoxy) naphthalene as the starting material, through a series of exquisite organic reactions, a complete carbon skeleton of natural products can be gradually constructed, and the total synthesis of natural products can be realized. In short, 1% 2C2-diene-3- (trienomethoxy) naphthalene, with its unique chemical structure, plays an indispensable role in the fields of medicine, materials and total synthesis of natural products, and promotes the continuous development of various fields.
    What are the physical properties of 1,2-difluoro-3- (trifluoromethoxy) benzene?
    1% 2C2-diethyl-3- (triethoxyformyl) benzene is an organic compound. Its physical properties are quite specific, and this is for you to describe in detail.
    Looking at its properties, it is usually a colorless to light yellow transparent liquid with a clear texture and no impurities visible to the naked eye. This substance has a certain degree of volatility, which can be slowly dissipated in the air, but the volatilization rate is not very fast.
    When it comes to odor, 1% 2C2-diethyl-3- (triethoxyformyl) benzene emits a mild and unique fragrant smell, which is not pungent and unpleasant, and is still pleasant.
    Its density is lighter than that of water. If it is placed in one place with water, it will float above the water surface and have a clear boundary. And it is insoluble in water, and the two are difficult to mix, showing a layered state. However, in organic solvents, such as ethanol, ether, and acetone, they have good solubility and can be uniformly mixed with organic solvents to form a uniform solution.
    The boiling point of 1% 2C2 -diethyl-3- (triethoxyformyl) benzene also has a specific value. Under specific pressure conditions, it can reach a certain temperature and boil and vaporize. This boiling point value is one of the important physical properties of this substance and is of great significance for its separation and purification operations.
    In addition, the melting point of this substance is also a key physical property. Under specific low temperature environments, 1% 2C2 -diethyl-3- (triethoxyformyl) benzene will transform from liquid to solid, and this transition temperature is its melting point. Knowing the melting point helps to determine the purity of the substance, and it is also crucial to control its storage and application conditions.
    What are the chemical properties of 1,2-difluoro-3- (trifluoromethoxy) benzene?
    The chemical properties of 1% 2C2-diene-3- (triene methoxy) benzene are worth exploring. The properties of this substance are related to the structure of its molecules. The position of 1,2-diene makes the molecule have active alkene properties and is easy to involve in addition reactions. Carbon-carbon double bonds, the domain of electron-rich, are easy to attack by electrophilic reagents. In case of hydrogen halide, it can form halogenated hydrocarbons, which is a classic electrophilic addition.
    And the part of 3- (triene methoxy), the methoxy group is connected to the benzene ring, which is the power supply group. It has the effect of modulating the electron cloud distribution of the benzene ring, which increases the density of the electron cloud of the benzene ring. Therefore, in the electrophilic substitution reaction, the substituents enter more ortho and para-sites. And the structure of the triene may make the molecule have the effect of conjugation, which affects its stability and reactivity. The conjugate system often decreases the molecular energy and increases the stability, and also affects the optical and electrical properties.
    In the stage of chemical reactions, this compound may exhibit a variety of reaction paths due to its unique structure. Its ethylene bond can react with nucleophiles, and the benzene ring attached to the methoxy group can involve various reactions of aromatic rings. Or it can be used in organic synthesis. After ingeniously designing the reaction, new compounds with special functions can be obtained. However, the control of the reaction requires considering the interaction of each group and selecting suitable conditions to achieve the expected results.
    What is the preparation method of 1,2-difluoro-3- (trifluoromethoxy) benzene?
    To prepare 1% 2C2-diene-3- (trienomethoxy) naphthalene, the method is as follows:
    First take an appropriate amount of naphthalene as the starting material, add a specific catalyst and organic solvent in a suitable reactor to create a stable reaction environment. Warm up to a specific temperature range, maintain this temperature condition, slowly add the reactant containing the diene structure, and continue to stir to make the reaction fully proceed. This step aims to make the naphthalene ring react with the diene part to form a preliminary intermediate.
    After the first step of the reaction reaches the expected level, the temperature is slightly cooled to another temperature range, and then the reagent containing triene methoxy is added, and the reaction conditions are adjusted again, so that the methoxy group can be successfully connected to the molecular structure, and the target product 1% 2C2-diene-3- (triene methoxy) naphthalene is further generated.
    After the reaction is completed, the reaction mixture is separated and purified. First, the method of filtration is used to remove insoluble impurities, and then the organic solvent and unreacted raw materials are separated by distillation according to the difference in the boiling point of each component. Then column chromatography was used to select suitable stationary phase and mobile phase, and the product was finely separated to obtain high-purity 1% 2C2-diene-3- (trienomethoxy) naphthalene. The whole process requires fine control of reaction conditions, raw material dosage and operation steps to obtain the ideal product.
    What are the precautions for storing and transporting 1,2-difluoro-3- (trifluoromethoxy) benzene?
    For 1% 2C2-diene-3- (triene methoxy) naphthalene, there are several points to pay attention to when storing and transporting.
    First, this material is active or lively, and it is easy to react with other things. Therefore, when storing, it is advisable to choose a dry, cool and well-ventilated place, and avoid coexistence with strong oxidizing agents, strong reducing agents, and strong acids, strong bases, etc., to prevent accidental transformation. If placed in an open, warm and humid place, or encountered impurities that can promote its reaction, it may cause qualitative change and damage its purity and utility.
    Second, during transportation, the packaging must be kept intact. If the package is damaged, this thing may leak out, which not only contaminates other things, but also increases the risk. The packaging materials used must be shock-resistant, pressure-resistant and well-sealed to prevent the intrusion of foreign objects. And the vehicles, boats, etc. transported should also be clean, and there is no residue sufficient to cause it to change.
    Third, the control of temperature and humidity is crucial. High temperature may cause it to evaporate, or cause decomposition and equalization; excessive humidity, or cause moisture, affecting quality. Therefore, during storage and transportation, it is appropriate to use equipment with temperature and humidity regulation to ensure a stable environment.
    Fourth, fire and explosion-proof is also a priority. This object may be flammable, but it is dangerous near fire and heat sources. In the place of storage and transportation, fireworks should be strictly prohibited, fire extinguishing equipment and explosion-proof measures should be set up, and the practitioners must also know the emergency response methods, just in case.
    Fifth, the logo is clear and easy to identify. On the packaging, the name, nature, danger and emergency measures of the object should be stated, so that the viewer can see at a glance, and the situation can be dealt with quickly.