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1,2-Difluoro-3-Methoxy-4-Nitrobenzene

1,2-Difluoro-3-Methoxy-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

543755

Chemical Formula C7H5F2NO3
Molar Mass 191.12 g/mol
Appearance Solid (presumably, based on similar compounds)
Solubility In Water Insoluble (expected for this type of aromatic nitro - fluoro - methoxy compound)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate (expected behavior)

As an accredited 1,2-Difluoro-3-Methoxy-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2 - difluoro - 3 - methoxy - 4 - nitrobenzene packaged in a sealed, labeled bottle.
Storage 1,2 - difluoro - 3 - methoxy - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent exposure to air and moisture. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions.
Shipping 1,2 - difluoro - 3 - methoxy - 4 - nitrobenzene, a chemical, is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous materials regulations to ensure safe transportation due to its potentially dangerous nature.
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1,2-Difluoro-3-Methoxy-4-Nitrobenzene 1,2-Difluoro-3-Methoxy-4-Nitrobenzene
General Information
Historical Development
Wen Fu 1, 2 - Difluoro - 3 - Methoxy - 4 - Nitrobenzene, its origin is also due to the study of all the sages. In the past, the scholars sought innovation and were different, exploring in the field of chemistry, hoping to obtain novel quality.
At the beginning, the research was still shallow, and many people were unaware of the synthesis method. However, the public was unremitting, after several years, repeated trials and errors, and finally obtained the synthesis path. Beginning with a simple method, although effective, the yield was not abundant, and the quality was not high.
After the scholars, continue the work of the past and strive for excellence. Study the mechanism of the reaction in detail, gain insight into the physical properties, improve the conditions, and optimize the steps. Therefore, the yield is gradually increasing and the quality is also good.
As for today, the preparation technology of 1,2-Difluoro-3-Methoxy-4-Nitrobenzene is quite mature. However, the road of chemistry is not endless, and scholars should still strive to promote its progress and develop its application in various fields.
Product Overview
1,2-Difluoro-3-methoxy-4-nitrobenzene is a chemical I have painstakingly researched. Its shape and color are specific, and it is in a crystalline state. Its color is nearly pure white and shimmer. Its properties are also unique. Under normal circumstances, it is quite stable. However, in case of heat, open flame or strong oxidizing agent, it will change or cause danger.
The method of synthesizing this product has been improved after several investigations. First, a specific benzene substrate is taken, accompanied by an appropriate agent, temperature control, pressure and timing. After multiple steps of delicate reactions, this product is obtained. The improvement of the yield is the focus of my research. After repeated debugging, it has now reached a considerable number.
It has a wide range of uses. In the field of medical research, it is a key raw material for the production of special drugs; in the field of agrochemistry, it is also an important role in creating high-efficiency pesticides. I hope this research can help this product develop its growth in various fields and benefit the world.
Physical & Chemical Properties
The physical and chemical properties of 1,2-difluoro-3-methoxy-4-nitrobenzene are also related to chemical research. The appearance of this compound may be in a specific state, or it may be crystalline, and the color may be different. Its melting point and boiling point are the keys to physical properties. The melting point is related to the temperature of the solid state to the liquid state, and the boiling point is the change from the liquid state to the gaseous state.
As for the chemical properties, the groups of fluorine, methoxy and nitro in its molecular structure all have unique reactivity. Fluorine atoms have high electronegativity, which affects the polarity and reaction check point of the molecule; methoxy groups have the property of supplying electrons, and nitro groups have strong electron-absorbing power. The two change the density of the electron cloud of the benzene ring in chemical reactions, causing its electrophilic and nucleophilic reactions to be different from benzene. In the field of organic synthesis, these properties can lead to various reactions and are the basis for the preparation of compounds with special structures.
Technical Specifications & Labeling
1,2-Difluoro-3-methoxy-4-nitrobenzene, its technical regulations and identification (product parameters) are related to the fine research of this product. For this product, the purity of the first raw materials in the technical regulations must be carefully selected, and impurities must be eliminated. The method of synthesis needs to be in a specific order, temperature control, speed regulation, and millimeter must be checked. When reacting, use accurate measurement to ensure the smooth process. In terms of identification, the composition and purity of the declaration should be confirmed by numbers and must not be confused. Its properties and uses should also be detailed, so that those who see it know its quality. On the packaging, mark with a warning to prevent accidental touch and misuse. In this way, with strict skills and clear analysis of the logo, we can ensure the excellence of this product and use it for all purposes, living up to the efforts of researchers.
Preparation Method
To prepare 1,2-difluoro-3-methoxy-4-nitrobenzene, the method is as follows:
Prepare various materials first, and select the raw materials. The starting materials are reacted by Miao Chemical. Take a certain material first, combine it with other agents, and under suitable temperature and pressure, stir slowly and respond. During this period, the heat and time need to be strictly inspected, and if there is a slight difference, it will affect the quality of the product.
Wait for the initial application to be completed, and transfer to the second process. After separation and purification, the hetero is removed and the essence is retained. Then add other agents to it, and proceed to the reaction step, control its rate, and stabilize its process.
It has been repeatedly transferred and fine-tuned. With the help of a catalytic agent, the yield is increased quickly. Finally, this product is obtained, and it is correct after inspection and meets the requirements. Every step should be recorded in detail for reference. This is the main method for preparing 1,2-difluoro-3-methoxy-4-nitrobenzene.
Chemical Reactions & Modifications
The research of modern chemistry is becoming more and more detailed in the change of things. Today there is 1,2-difluoro-3-methoxy-4-nitrobenzene, and its chemical adaptation and modification are of great importance to the academic community.
The chemical adaptation of husband is related to the clutch of molecules and the translocation of atoms. 1,2-difluoro-3-methoxy-4-nitrobenzene under various reaction conditions, or bond cracking and new formation, or group migration, resulting in its sexual transformation.
As for modification, it is intended to have better characteristics. Or increase its stability, or change its solubility, or change its inverse nature, so as to be suitable for various applications. Chemists use various methods, such as temperature change, pressure regulation, catalyst selection, etc., to achieve this purpose.
Although the research path is not smooth, but unremitting exploration will surely be able to understand its chemical application and modification, and contribute to the progress of chemistry and the wide use of materials.
Synonyms & Product Names
1,2-Difluoro-3-methoxy-4-nitrobenzene is also a chemical substance. In today's chemical research, this substance is often found. However, it is also important to find its synonymous name and the name of the commodity.
Guanfu's ancient books, although there is no such precise chemical name, in today's world, the chemical is refined, and the material name is diverse. 1,2-difluoro-3-methoxy-4-nitrobenzene, or its synonymous name, is used by researchers. And the name of the product, or according to the regulations of the manufacturer and the different uses.
In the field of research, its synonymous name can be used by all parties; knowing the name of its product, it can be purchased and applied. This is all known to chemical researchers, in order to help the progress of research and promote the progress of science.
Safety & Operational Standards
1,2-Difluoro-3-methoxy-4-nitrobenzene is also one of the chemical products. Its safe production and operation practices, we should be cautious.
The preparation of this thing must be done in a well-ventilated secret room. All operators need complete protective equipment, such as gas masks, protective gloves and protective clothing, to prevent it from contacting the skin and respiratory tract. The temperature and humidity of the room should also be carefully regulated and acted according to specific procedures, so as not to make a slight difference.
Its storage should also be in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with oxidizing agents, reducing agents, etc., for fear of violent reactions. The reservoir must be tightly sealed to prevent leakage.
If there is a leak, the first thing to do is to evacuate the surrounding people and ban all fire sources. The operator quickly uses professional protective equipment to deal with the leakage. Small leaks can be adsorbed and contained by inert materials such as sand and vermiculite; large leaks need to be built embankments or dug for containment, and professional equipment should be recycled or transported to the designated place for proper disposal.
During transportation, it is also necessary to strictly abide by the specifications. Choose suitable transportation equipment to ensure its stability. During transportation, avoid vibration, impact and friction to prevent leakage caused by damaged packaging.
In short, the safety and operation standards of 1,2-difluoro-3-methoxy-4-nitrobenzene are related to the safety of everyone and the tranquility of the environment. All practitioners should be well aware of their reasons, follow them carefully, and do not slack in the slightest.
Application Area
1,2-Difluoro-3-methoxy-4-nitrobenzene, this compound has a wide range of uses. In the field of pharmaceutical research and development, because of its unique chemical structure, it may be used as a key intermediate to help create new specific drugs and open up new paths for the treatment of diseases. In the field of materials science, with its special properties, it can participate in the synthesis of high-performance materials, such as optimizing the properties of electronic materials, so that they can play key functions in electronic devices. Or in the field of fine chemicals, it can be used to prepare high-end fine chemicals to improve product quality and characteristics. All these applications, due to the unique chemical properties of this compound, reveal extraordinary value in various fields, inject impetus into scientific research and industrial development, and lead the way forward.
Research & Development
In recent years, I have focused on the study of chemical products, focusing on 1,2-difluoro-3-methoxy-4-nitrobenzene. Its unique properties, in various reactions, often show a different state.
At the beginning, I explored the method of its synthesis, tried many methods, or the raw materials were rare, or the steps were complicated and the results were not obvious. However, I did not give up, I devoted myself to studying, went through the classics, visited various houses, and finally obtained a method, which can be more stable.
Then, study its properties. Observe its solubility in different solvents, observe its changes when heated and exposed to light. Try to react with other substances, find its laws, and hope to expand its use.
As for the field of application, the prospect is promising. In the synthesis of medicine, it can be used as a key intermediate, which is expected to help the creation of new drugs. And in the field of materials, it may also be able to develop unique capabilities. Yu Dang unremitting, deep cultivation, hope to promote the development of this chemical, add new color to the academic industry.
Toxicity Research
There is now a substance named 1,2-difluoro-3-methoxy-4-nitrobenzene. We focus on the study of toxicants to investigate its properties in detail. This substance has a unique structure, fluorine, methoxy group and nitro group are combined in the benzene ring.
Taste its toxicity, or because of nitro groups, it has strong oxidative properties, which can disturb the balance of redox in organisms. The introduction of fluorine atoms increases its lipid solubility, easily enters the biofilm, and impairs cellular function. Methoxy groups affect the distribution of molecular charges, or involve the interaction with biological macromolecules.
However, to clarify the details, more methods are needed. To observe its effect on cell proliferation and apoptosis by cell experiments, and to explore its damage to the body's organs by animal experiments. After this study, the depth of its toxicity can be known, which provides a basis for protection and detoxification strategies, and protects life from its harm. It also has guiding benefits in the chemical and pharmaceutical industries.
Future Prospects
The vision of the future, which is of great importance to our chemical researchers. Today, there are 1,2-difluoro-3-methoxy-4-nitrobenzene, which can be used in the field of chemical production.

The combination of fluorine, methoxy and nitro groups, and its characteristics. In the future, it can be used in fine chemical synthesis, which is the cornerstone of many high-value-added products. It is expected to overcome diseases in the field of research, or through its special design, the development of new molecules.
Furthermore, in the field of materials, it may be possible to cleverly make it into a high-performance material and improve the properties of materials. However, in order to achieve this state, we still need our unremitting research, understanding its nature, and understanding its opposite principles. Only then can we fully release its unfinished power and open up a new world.
Where to Buy 1,2-Difluoro-3-Methoxy-4-Nitrobenzene in China?
As a trusted 1,2-Difluoro-3-Methoxy-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Difluoro-3-Methoxy-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1,2-difluoro-3-methoxy-4-nitrobenzene?
1% 2C2-diene-3-methoxy-4-carbonylbenzene, this is an organic compound. Looking at its structure, its physical properties are unique.
First of all, its physical state is at room temperature and pressure, or it is a solid, because of the intermolecular force. Polar groups such as carbonyl and methoxy in the molecule can cause hydrogen bonds or dipole-dipole interactions between molecules, which promote the molecules to be closely arranged and appear in a solid state.
Secondary and melting point, due to the strong intermolecular force, it takes more energy to destroy its lattice, so the melting point is relatively high. The interaction between polar groups binds the molecules in the lattice. To melt it, it needs to be heated to provide enough energy to overcome this interaction.
Re-discuss the boiling point. Also due to the strong force between molecules, the gasification needs to overcome a large resistance, and the boiling point will be quite high. To get the molecule out of the liquid phase and become the gas phase, a large amount of energy needs to be input to break the hydrogen bond and dipole-dipole interaction between molecules.
In terms of solubility, because it contains polar methoxy and carbonyl groups, it may have a certain solubility in polar solvents, such as alcohols and ketones. Interactions between polar solvent molecules and polar groups of compounds can be formed, such as hydrogen bonds, to help them dissolve. However, in non-polar solvents, such as alkanes, the solubility may be very small. Due to the weak interaction between non-polar solvents and polar compounds, it is difficult to overcome the intermolecular force of the compound to disperse it in the solvent.
The color state of this compound may be colorless or white solid, and most organic compounds with such structures have this color state. If there is no conjugate system large enough or special chromophore in the structure, it generally does not absorb visible light, so it is colorless or white.
The density may be relatively large. Due to the large relative atomic mass of carbon atoms and oxygen atoms in the molecule, and the tight molecular structure, the mass per unit volume is higher.
What are the chemical properties of 1,2-difluoro-3-methoxy-4-nitrobenzene?
1% 2C2-diene-3-methoxy-4-benzylnaphthalene is one of the organic compounds. Its chemical properties are unique and valuable to explore.
In this compound, the structure of 1% 2C2-diene gives it a certain activity. The carbon-carbon double bond is a reactive activity check point and is prone to addition reactions. In case of electrophilic reagents, electrophilic addition can be initiated. For addition to hydrogen halide, the halogen atom will be added to the carbon atom containing less hydrogen, following the Markov rule. And because of the structure of conjugated dienes, the Dils-Alder reaction can be carried out to form hexamembered cyclic compounds with dienophiles. This reaction is of great significance in organic synthesis and can construct complex cyclic structures. In the
3-methoxy group, the methoxy group is the power supply group, which affects the electron cloud distribution of the molecule through its induction effect and conjugation effect. In the electrophilic substitution reaction of the benzene ring, the electron cloud density of the adjacent and para-site of the benzene ring increases, and it is easier to replace in the adjacent and para-site, which can improve the reaction activity and the regioselectivity of the left and right reactions.
4-benzylnaphthalene part, the naphthalene ring is aromatic and relatively Benzyl is connected to methylene because the benzene ring, methylene hydrogen has a certain activity, can be oxidized, and can also undergo substitution reactions.
The chemical properties of this compound make it have unlimited potential in organic synthesis, medicinal chemistry and other fields. It can be used as a synthetic intermediate, and complex molecular structures can be constructed through various reactions to develop new drugs or materials, making great contributions to the development and practical application of chemical science.
What are the common methods for synthesizing 1,2-difluoro-3-methoxy-4-nitrobenzene?
The common synthesis method of 1% 2C2-diene-3-methoxy-4-acetylbenzene can be based on the principles of ancient methods and chemical regulations.
First, benzene is used as a group, and halogen atoms are introduced into the benzene ring by halogenation. If iron bromide is used as a catalyst, bromine and benzene are co-heated to obtain bromobenzene. This is a halogenation reaction. The reason is that the catalyst promotes the polarization of halogen molecules, electrophilic attacks the benzene ring, breaks its conjugate system, and forms halogenated benzene.
Then, bromobenzene is reacted with methoxylation reagents. Sodium methoxide or the like can be used, and the reaction can be heated in a suitable solvent, such as anhydrous ethyl ether. This is a nucleophilic substitution reaction. The methoxy negative ion nucleophilically attacks the halogen atom-linked carbon of bromobenzene, and the halogen ion leaves to obtain 3-methoxy bromobenzene. Because the oxygen of the methoxy group has lone pairs of electrons, it is rich in electrons, and it is easy to find electron-deficient carbon and combines with it.
Then it is acetylated. Acetyl chloride is used as the acetyl donor, anhydrous aluminum trichloride is used as the catalyst, and reacts with 3-methoxy bromobenzene at low temperature. In this case, aluminum trichloride activates acetyl chloride, making its carbonyl carbon more positively charged and vulnerable to the electron cloud attack of the benzene ring, forming 1-acetyl-3-methoxy bromobenzene. This is the application of Fu-Ke acylation reaction, with the power of the catalyst to achieve the purpose of introducing acyl groups.
After coupling reaction, a palladium catalyst, such as tetra (triphenylphosphine) palladium, reacts with a diene-containing reagent under basic conditions. The basic environment can help the palladium catalyst activate the substrate, so that the two are coupled to obtain 1% 2C2-diene-3-methoxy-4-acetylbenzene. This coupling reaction can cleverly form carbon-carbon bonds, which is a key step in the synthesis of complex structures. Each step requires temperature control, time control, and selection of appropriate solvents and catalysts to achieve the best synthesis effect.
In what fields is 1,2-difluoro-3-methoxy-4-nitrobenzene used?
1% 2C2-diene-3-methoxy-4-acetylbenzene, this substance has a wide range of uses. In the field of medicine, it can be used as a key intermediate for the synthesis of a variety of specific drugs. Due to its unique chemical structure, it can precisely combine with specific targets in organisms to help develop new drugs for specific diseases.
In the field of materials science, it also has extraordinary applications. It can participate in the preparation of high-performance polymer materials. By skillfully adjusting the reaction conditions, it can be integrated into the polymer skeleton, thereby improving the mechanical properties, thermal stability and other key characteristics of the material, and contributing to the manufacture of high-end materials.
In the fine chemical industry, it is an important raw material for the synthesis of various fine chemicals. After a series of chemical reactions, it can be converted into compounds with special functions, such as fragrances, additives, etc., which greatly enriches the variety of fine chemical products and meets the diverse needs of the market.
In terms of scientific research and exploration, researchers often conduct in-depth research on this substance, through in-depth exploration of its chemical properties and reaction laws, open up new chemical reaction paths, promote the progress of organic chemistry theory and technology, and inject vitality into the development of chemistry.
What is the approximate market price of 1,2-difluoro-3-methoxy-4-nitrobenzene?
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