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1,2-Difluoro-3-Iodobenzene

1,2-Difluoro-3-Iodobenzene

Hongda Chemical

Specifications

HS Code

495901

Chemical Formula C6H3F2I
Molecular Weight 254.0
Appearance Liquid (usually)
Boiling Point Approx. 190 - 192 °C
Density Approx. 2.03 - 2.05 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Stability Stable under normal conditions, but reactive with strong oxidants

As an accredited 1,2-Difluoro-3-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2 - difluoro - 3 - iodobenzene packaged in a sealed glass bottle.
Storage 1,2 - difluoro - 3 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent vapor leakage. As it is a chemical, store it separately from oxidizing agents, reducing agents, and other incompatible substances to avoid potential reactions. Label the storage container clearly for easy identification and safety.
Shipping 1,2 - difluoro - 3 - iodobenzene is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. These containers safeguard the chemical during transit, ensuring safety and preventing leakage.
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1,2-Difluoro-3-Iodobenzene 1,2-Difluoro-3-Iodobenzene
General Information
Historical Development
1,2-Difluoro-3-iodobenzene is also an organic compound. At the beginning, chemists worked hard to explore the method of synthesis. At the beginning, the technology was not ready, the synthesis was difficult, and the obtained product was impure and the amount was scarce.
As the years passed, all kinds of technologies became more and more exquisite. Chemists worked tirelessly on reaction conditions and catalysts. Gradually, the synthesis path can be optimized to improve the purity and yield of the product. In the past, synthesis required complicated steps, which took a long time and cost. Today is different from the past, with new techniques, simplified steps, and greatly increased efficiency.
Looking at its use, it has emerged in the fields of pharmaceutical research and development, materials science, etc. From this perspective, since the birth of 1,2-difluoro-3-iodobenzene, through the efforts of chemists, in the evolution of technology, the use has become wider and the prospect has become brighter.
Product Overview
Today there is a substance called 1,2-difluoro-3-iodobenzene. Its shape is an organic compound with a delicate structure. Looking at the structure of its molecule, the difluoro atom and the iodine atom each occupy a specific position in the benzene ring, which makes this compound unique.
This substance is widely used in the field of organic synthesis. It can be used as a key intermediate to assist in the construction of many complex organic molecules. With its special chemical activity, it can react with a variety of reagents, opening the door to a variety of synthesis paths.
The preparation method often requires exquisite chemical skills and specific reaction conditions. In a suitable solvent, the corresponding raw materials can be gradually converted according to the established reaction mechanism to obtain this pure product. However, the preparation process requires strict control of various variables to ensure the quality and yield of the product.
Physical & Chemical Properties
1,2-Difluoro-3-iodobenzene is also a chemical substance. Its physical and chemical properties are related to the research. Looking at its shape, at room temperature, or as a colorless liquid, its quality is pure and stable. Its boiling point, due to the attractive force between molecules, has a specific number, which is the key characteristic of the gasification of substances. As for the melting point, it also has characteristics, which is the boundary between the transition of solid and liquid states.
Its solubility, in organic solvents, or in a good state, according to the principle of similar compatibility, is compatible with organic molecules. In terms of chemical activity, the position of fluorine and iodine makes it capable of participating in many reactions. Fluorine has strong electronegativity and iodine has great polarizability. The synergy between the two makes this compound useful in organic synthesis, or as a starting material for reactions, leading to a variety of chemical changes. It is useful in the fields of chemical and pharmaceutical research and development.
Technical Specifications & Labeling
Today there is a product named 1,2-difluoro-3-iodobenzene. Its process specifications and identification (product parameters) are the key. Looking at this substance, its color is pure and uniform, and when it meets specific purity standards, the impurity content must be minimal. Its properties are stable, and it is not easy to combine with others in conventional environments. The physical and chemical characteristics are in line with the regulations.
On the label, the ingredients are detailed to inform everyone of its chemical composition. The product parameters are also listed in detail, such as melting point, density, etc., which are all accurate and can be followed by the user. This is the essence of the process specifications and identification (product parameters), which is related to its quality. Users should carefully observe it in order to make good use of this product and make the best use of it.
Preparation Method
If you want to make 1,2-difluoro-3-iodobenzene, you should consider the preparation method in detail. The selection of raw materials is very critical, and specific compounds containing fluorine, iodine and benzene rings can be used as starting materials. The preparation process first reacts with a suitable fluorine-containing reagent and a benzene-containing ring substrate under specific conditions to introduce fluorine atoms. This step requires attention to the choice of reaction temperature, time and catalyst to ensure that the reaction proceeds in the desired direction.
After the fluorine atom is introduced, the iodine atom is introduced. The principle of halogenation reaction can be used to react with the previous product with an iodine source reagent. The reaction steps need to be gradual. After each step of the reaction is completed, the product should be properly separated and purified to remove impurities.
In order to ensure the high efficiency and stability of the reaction, a suitable catalytic mechanism can be constructed. The selection of a specific catalyst can reduce the activation energy of the reaction, improve the reaction rate and selectivity. In this way, through careful planning of raw materials and preparation processes, strict control of reaction steps and rational construction of catalytic mechanisms, it is expected to obtain the target product 1,2-difluoro-3-iodobenzene.
Chemical Reactions & Modifications
1,2-Difluoro-3-iodobenzene is also an organic compound. In the field of chemistry, it is our responsibility to explore its reaction and modification.
Looking at the reaction of this compound, the activity of fluorine and iodine atoms leads to various chemical changes. Fluorine has strong electronegativity, which changes the density of the electron cloud at the ortho position, resulting in different reactivity. Although iodine is large in volume, it has good leaving properties. It can be a key step in reactions such as nucleophilic substitution.
As for modification, chemical means can be used to adjust its functional groups, increase its stability or change its physicochemical properties. If the substituents of fluorine and iodine are changed with appropriate reagents, new derivatives can be obtained, which have different activities and uses. This is useful in creating new drugs, optimizing material properties, etc. After careful study of reaction and modification, the potential of 1,2-difluoro-3-iodobenzene will be able to be used by us to the best of our ability and contribute to the development of chemistry.
Synonyms & Product Names
1,2-Difluoro-3-iodobenzene is also a new product of chemistry. In the field of chemistry, each of these compounds has an alias and a trade name. Its alias, or according to the characteristics of its structure, or according to the rules of the past. The name of the trade, is to recognize its characteristics, and to attract the attention of the public.
1,2-difluoro-3-iodobenzene, or is called by other names, this is due to the title of the chemical world, from time to time. Although it is one thing, the name is different, but it can also see the change of the academic world and the business plan. Aliases or according to the row of molecules, the group of atoms obtained, so that the researcher can understand its structure. The name of the product is more than its merit and quality, and it is good to sell.
In the eyes of researchers, it is clear that its alias and trade name are known, but it is beneficial to know the names of this thing, which is useful for investigating texts and purchasing materials. It can avoid confusion, be accurate, and benefit research. Therefore, knowing the same name and trade name of 1,2-difluoro-3-iodobenzene is a must for chemical researchers.
Safety & Operational Standards
Safety and Operation Specifications for 1,2-Difluoro-3-iodobenzene
For those with 1,2-difluoro-3-iodobenzene, it is also a substance used in chemical research. If you want to use this product, the first priority is safety, and you must follow the operating specifications to keep it safe.
This product has certain dangers. It is chemically active and changeable. If it comes into contact with the skin, it may cause irritation, such as redness, swelling, and pain. In the eyes, the damage is especially serious, and the vision may be damaged. Therefore, when operating, be prepared with protective materials. Wear protective clothing, which is dense and strong, and can resist its damage. Wear protective gloves with suitable materials to prevent its invasion. The face is equipped with protective glasses, transparent and clear, to protect the eyes.
In the operating place, it must be well ventilated. If the space is blocked, the volatile gas of this object will accumulate, and it will be dangerous to explode in case of open fire or hot topic. And the operating table, when kept clean and dry, do not let debris accumulate to prevent affecting the experiment or causing accidents.
When taking 1,2-difluoro-3-iodobenzene, the action should be slow and stable. Use clean and accurate utensils and take the amount required by the experiment. Do not be greedy for too much or take less. After measuring, quickly seal the container and place it in a cool and dry place, away from heat and fire sources.
After the experiment is completed, the remnants should not be discarded at will. According to the regulations of chemical waste treatment, collect them by classification and dispose of them properly. The utensils used should be cleaned immediately to remove their residues for reuse.
In short, in the industry of 1,2-difluoro-3-iodobenzene, when you are in awe and strictly abide by safety and operating standards, you can avoid danger and move forward steadily on the road of scientific research.
Application Area
1,2-Difluoro-3-iodobenzene is also a chemical substance. Its application field is especially wide. In the field of medicinal chemistry, it can be a key intermediate to help create special new drugs, cure various diseases, and save people's suffering. In the field of materials science, it is also of great use. Based on this, novel functional materials can be developed for electronic devices to increase their performance and make them more delicate and efficient.
Looking at the past, all chemical substances have their unique uses. This 1,2-difluoro-3-iodobenzene has been studied by capable people and gradually shows its wonders. Its application in different fields is like the stars in the sky, each shining brightly. The road of medical development depends on this to explore new paths; the road of material innovation is based on it to open up avenues. It is an indispensable thing in chemical research and has far-reaching significance in many application fields. It lays the foundation and guides the direction for future development.
Research & Development
In recent years, Yu dedicated himself to the research of 1,2-difluoro-3-iodobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored the method of its preparation, tried all kinds of things, and went through hardships. The choice of raw materials and the conditions of the reaction all need to be carefully considered. If there is a slight mistake, the result will be wrong.
Continuous research, and finally achieved. Optimize the process to gradually increase the yield. Then study its reaction mechanism to show its characteristics in various reactions.
Looking at its application prospects, it can be used as a key intermediate and participate in the construction of a variety of complex organic molecules. In pharmaceutical research and development, materials science, etc., are expected to open up new trends.
I will continue to make progress, hoping to further tap its potential, promote its wide application, and contribute to the development of science and technology.
Toxicity Research
Since modern times, chemical refinement has led to the emergence of various compounds. Today, there is 1, 2 - Difluoro - 3 - Iodobenzene, and its toxicity research is of great significance.
To observe the road of toxicity investigation, it is first necessary to investigate its physicochemical properties in detail. 1, 2 - Difluoro - 3 - Iodobenzene has a unique structure. Fluorine and iodine atoms are attached to the benzene ring, or their activities are different. In various solvents, its dissolution properties may affect its transmission and distribution in organisms.
Furthermore, consider its biological effects. Take various creatures as samples to observe their reactions after ingesting this substance. Or see changes in physiological functions, damage to organs, and changes in behavior. At the cellular level, explore its effects on cell proliferation and apoptosis, and see if it interferes with the normal metabolic pathways of cells.
In the human environment, the degradation and transformation of this substance cannot be ignored. Its migration between soil and water bodies and the toxicity of degradation products are all important for toxicity research. After these investigations, a complete picture of the toxicity of 1,2-Difluoro-3-Iodobenzene can be obtained, which is the basis for protection and application.
Future Prospects
The future development is about 1,2-difluoro-3-iodobenzene, and my heart is full of expectations. Although this chemical product is currently in the realm of research, its prospects are like the beginning of the stars, and it is expected to become brighter.
Looking at the field of chemistry, new things often lead to changes. 1,2-difluoro-3-iodobenzene has emerged in many aspects such as material creation and medical research and development. In the field of materials, it may be able to generate new materials with specific properties, which will contribute to the progress of science and technology; in the road of medicine, it may become a sharp blade to overcome difficult diseases and benefit the common people.
Our generation should explore its mysteries with diligence and study. With time, 1,2-difluoro-3-iodobenzene will bloom and paint a picture of the future, leading the field of chemistry to a new course.
Where to Buy 1,2-Difluoro-3-Iodobenzene in China?
As a trusted 1,2-Difluoro-3-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Difluoro-3-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-difluoro-3-iodobenzene?
1,2-Diene-3-alkynylbenzene has a wide range of main uses. In the field of organic synthesis, it is often used as a key intermediate and participates in the construction of many complex organic compounds by virtue of its unique structure. Through carefully designed chemical reactions, it can be converted into drug molecular precursors with specific biological activities, opening up new paths for drug research and development. For example, in the synthetic route exploration of some anti-tumor drugs, 1,2-diene-3-alkynylbenzene can be used as a starting material and modified by multi-step reactions to obtain compounds with potential anti-cancer activity.
In the field of materials science, it also has important applications. Due to its unique conjugate structure, it can be used to prepare materials with special photoelectric properties. For example, copolymerization with other conjugated monomers can obtain luminescent materials that can be used in organic Light Emitting Diodes (OLEDs), endowing the materials with unique luminous wavelengths and efficient luminous efficiency, and improving the display quality of OLED screens.
Furthermore, in the field of supramolecular chemistry, 1,2-diene-3-alkynylbenzene can utilize its π-π stacking action and active check points such as alkynyl groups to construct novel supramolecular structures. With this, it is expected to realize the identification and enrichment of specific molecules, and show the potential application in chemical sensors, which can sensitively detect specific substances in the environment, such as harmful gases or heavy metal ions.
What are the physical properties of 1,2-difluoro-3-iodobenzene?
1% 2C2-diene-3-naphthol is an organic compound, and its physical properties are as follows:
In terms of appearance properties, under normal conditions, 1% 2C2-diene-3-naphthol is mostly white to light yellow crystalline powder, which may gradually darken in color in light and air. This is because the naphthalene ring, alkenyl group and phenolic hydroxyl group in its molecular structure are relatively active, vulnerable to light and oxygen, triggering oxidation and other reactions, resulting in color changes.
At the melting point, the melting point of the compound is about 120-125 ° C. As an important physical property of a substance, the melting point is determined by its intermolecular forces. 1% 2C2-diene-3-naphthol molecules have van der Waals forces, hydrogen bonds and other interactions. When heated, sufficient energy is required to overcome these forces, so that the crystal lattice is destroyed, and then melted. This specific melting point range can be used as one of the basis for identifying this compound.
In terms of solubility, 1% 2C2-diene-3-naphthol is slightly soluble in water, but easily soluble in organic solvents such as ethanol, ether, and chloroform. This is because water is a polar solvent, while in 1% 2C2-diene-3-naphthol molecules, although the phenolic hydroxyl group has a certain polarity, the naphthalene ring and the alkenyl group are non-polar parts, and the overall polarity is weak. According to the principle of "similar miscibility", it has better solubility in organic solvents with low polarity.
In addition, 1% 2C2-diene-3-naphthol has sublimation properties, and can be directly converted from solid to gaseous state at specific temperatures and pressures. This property is related to intermolecular forces and vapor pressure, and it can be purified by using sublimation properties.
What are the chemical synthesis methods of 1,2-difluoro-3-iodobenzene?
There are many methods for the chemical synthesis of 1,2-diethylene-3-thiophene, each of which has its own advantages and has its own uses in different situations.
First, halogenated aromatics and thiophene derivatives are used as raw materials, and the coupling reaction is catalyzed by palladium. This is a commonly used method, such as bromoaromatics and 2-thiophene boronic acid, in the presence of palladium catalyst, base and ligand, heated in a suitable solvent, the target product can be obtained. This reaction has good selectivity and high yield, but the cost of palladium catalyst is high, or its large-scale application is limited.
Second, it is prepared by the functionalization of thiophene rings. The thiophene is first functionalized to a specific group, and then divinyl is introduced through a series of reactions. For example, using thiophene as the starting material, bromothiophene is first brominated, and then reacted with vinyl Grignard reagent or lithium reagent to introduce vinyl. This method is slightly complicated, but the raw materials are easy to obtain, the operation is relatively simple, and it is more suitable for laboratory synthesis.
Third, the intramolecular cyclization reaction is used. Using a chain-like compound containing an appropriate functional group as the raw material, the thiophene ring is constructed by intramolecular cyclization and vinyl is introduced. This approach has high atomic economy and short steps, but it requires strict reaction conditions and precise control of reaction parameters.
Fourth, the cyclization addition reaction catalyzed by transition metals is used. For example, alkynes and nitriles are cyclized to form thiophene derivatives under the catalysis of transition metals, and then further modified to introduce vinyl. This is a new method with innovation and potential, but the reaction mechanism is complex and needs to be further studied and optimized.
What are the precautions for storing and transporting 1,2-difluoro-3-iodobenzene?
1% 2C2-diethylene-3-naphthalene anthracene is very important during storage and transportation.
First, the control of temperature. This substance is more sensitive to temperature changes, and high temperature can easily cause changes in its properties, or even cause chemical reactions. Therefore, when storing, it needs to be placed in a cool place, usually the temperature should be controlled below 20 degrees Celsius to ensure its chemical stability. During transportation, it is also necessary to beware of direct sunlight and high ambient temperature. Heat insulation equipment and cold chain transportation can be used. If conditions permit, a temperature monitoring device can be prepared for real-time monitoring. If the temperature exceeds the limit, take cooling measures in time.
Second, humidity prevention. Humid environment or cause 1% 2C2-diethylene-3-naphthalene anthracene to absorb moisture, which in turn affects its quality. The storage place should be kept dry, and the relative humidity should be maintained below 50%. A desiccant can be built into the storage space and replaced regularly to absorb water vapor. The transportation container must also ensure that it is well sealed to prevent the intrusion of external moisture.
Third, the packaging is proper. Suitable packaging materials must be selected. This substance may be corrosive or reactive to a certain extent. The packaging material should be compatible with it and do not chemically react. It is commonly used in containers made of glass, special plastics, etc., and the container should be strong to prevent damage and leakage due to collision and extrusion during transportation. Warning labels should be clearly marked on the outside of the package, such as "flammable" "harmful" and other words to remind relevant personnel to pay attention.
Fourth, isolation and protection. 1% 2C2-diethylene-3-naphthalene anthracene should not be mixed with oxidants, acids, bases and other substances. Because of its active chemical properties, contact with it or cause a violent reaction, endangering safety. Operators and transporters should be equipped with corresponding protective equipment, such as protective clothing, gloves, goggles, etc., to avoid direct contact. If they are inadvertently touched, they should immediately rinse with a large amount of water and seek medical attention in time.
What is the approximate market price of 1,2-difluoro-3-iodobenzene?
I have heard your inquiry about the approximate market price of 1,2-diethyl-3-chlorothiophene. However, the price of this chemical often varies due to time and place, supply and demand, quality and many other factors, so it is difficult to determine the exact number.
Watching the city's easy picture, if the supply of this product exceeds the demand, the price may decline; if the demand exceeds the supply, the price will rise. And the quality of its quality is also the key to pricing. It is reasonable to say that the better one has a high price, and the second one has a low price.
Furthermore, the difference in region also has an impact. The prosperous capital is Dayi, with convenient transportation, low logistics costs, and slightly different prices than remote places. And the dimension of time, different years of age, the price is also different. On the occasion of new production, the price may be flat due to large quantities; after long storage, the price may change due to wear and tear.
To know the exact market price, consult chemical market merchants, industry brokers, or refer to professional chemical market information platforms to get a near-real price.