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1,2-Dichloro-4-(Trifluoromethyl)Benzene

1,2-Dichloro-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    321520

    Chemical Formula C7H3Cl2F3
    Molecular Weight 215.00
    Appearance Colorless to light yellow liquid
    Boiling Point 184 - 186 °C
    Density 1.489 g/cm³
    Solubility In Water Insoluble
    Flash Point 68 °C
    Refractive Index 1.459 - 1.461

    As an accredited 1,2-Dichloro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2 - dichloro - 4 - (trifluoromethyl)benzene: 500 mL in glass bottle with tight - fitting cap.
    Storage 1,2 - Dichloro - 4 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent reactions. This ensures safety and maintains the chemical's integrity.
    Shipping 1,2 - dichloro - 4 - (trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring safe transportation to prevent any environmental or safety risks.
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    1,2-Dichloro-4-(Trifluoromethyl)Benzene 1,2-Dichloro-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1,2-Dichloro-4- (trifluoromethyl) benzene is also an organic compound. Its origin can be traced back to the process of chemical research in the past. At the beginning, the chemical sages were still groping for the principles of chemical synthesis. After further research, various technologies have gradually improved.
    In the past, the experimental conditions were simple and stingy, but chemists were determined and unremitting explorations. At some point, there was a way to make this 1,2-dichloro-4- (trifluoromethyl) benzene. At the time of initial production, the yield was meager and the purity was not perfect.
    With the prosperity of science, the method of preparation has improved day by day. The equipment is updated and the theory is complete. The yield and purity of this compound are gradually increasing. From the occasional products obtained in the past, it has gradually become an industrially usable material. It has emerged in various fields of chemical industry, adding a chapter to the history of chemistry. Its development process has witnessed the rise of chemistry.
    Product Overview
    1,2-Dichloro-4- (trifluoromethyl) benzene is one of the most studied in chemistry. It is an organic halide with unique chemical properties. Looking at its structure, above the benzene ring, chlorine atoms and trifluoromethyl are arranged in an orderly manner, and this specific structure gives it its specificity.
    This substance is a colorless liquid at room temperature, with a slightly pungent taste. Its boiling and melting point have certain values due to its structure, and it has a wide range of uses in the field of organic synthesis. It can be used as an intermediate, and through many reactions, other compounds can be derived for the creation of medicines and pesticides.
    When preparing, it is necessary to operate with caution. Because it contains halogen atoms and fluoromethyl, the control of reaction conditions and the combination of raw materials are all about success or failure and quality. And this material may have certain toxicity and environmental impact, and it should not be ignored after use.
    Physical & Chemical Properties
    1,2-Dichloro-4- (trifluoromethyl) benzene, its material has specific physical and chemical properties. Looking at its shape, it is a colorless to slightly yellow liquid at room temperature, and the pure one is clear and less heterogeneous. Its taste is slightly irritating, and the smell can be known. In terms of boiling point, it is about a certain temperature. At this temperature, it liquefies into gas, which is the key characteristic of its gas-liquid phase transition. Its density is moderate, and it has its unique specific gravity among similar substances. As for solubility, it can be soluble in specific organic solvents, but it is difficult to dissolve in water, due to the molecular structure. Its chemical properties, when encountering certain reagents, can react such as substitution and addition, all due to the activity of inter-atomic bonds in molecules. From this perspective, the physical and chemical properties of 1,2-dichloro-4- (trifluoromethyl) benzene have unique uses and research value in chemical industry, scientific research and other fields.
    Technical Specifications & Labeling
    1,2-Dichloro-4- (trifluoromethyl) benzene is also an organic compound. The technical specifications and labeling (product parameters) for its preparation are crucial.
    The preparation method requires specific steps and conditions. The choice of raw materials must be carefully selected, and the proportion must also be precisely prepared. During the reaction, temperature, pressure and other conditions must be strictly controlled. A slight difference will affect the purity and yield of the product.
    In terms of labeling, its appearance and properties should be clearly marked, such as color, taste, and state. And key product parameters, such as melting point, boiling point, purity, etc., should not be missed. Precise marking allows users to understand its nature and use, which is beneficial for industrial production and scientific research experiments. Strictly abide by technical specifications and clear labels to obtain high-quality 1,2-dichloro-4- (trifluoromethyl) benzene products.
    Preparation Method
    To prepare 1,2-dichloro-4- (trifluoromethyl) benzene, the method is as follows: Prepare raw materials, which need to be based on chlorine and fluorine-containing compounds, such as chlorobenzene derivatives and fluorine-containing reagents. The preparation method involves chemical technology, and rigorous steps should be followed.
    Start, take a suitable chlorobenzene substrate, and add an appropriate amount of fluorine-containing reactants to a specific reaction vessel. With the help of a catalyst, the temperature is controlled within a certain range to make the two react. In this reaction step, the temperature and the ratio of the reactants are critical, and a slight difference in the pool will affect the purity and yield of the product.
    After the reaction is completed, it is separated and purified. First, by distillation method, according to the difference in boiling point of each component, preliminary separation. After chromatography, fine purification, to obtain pure 1,2-dichloro-4- (trifluoromethyl) benzene.
    This preparation process, all links are closely linked, the quality of raw materials, reaction control, purification method, are to obtain high-quality products.
    Chemical Reactions & Modifications
    There is a substance named 1,2-dichloro-4- (trifluoromethyl) benzene. In the field of chemistry, it is the priority of our researchers to explore its reaction and modification.
    Looking at its reaction, this substance is often involved in the genera of substitution and addition. The substitution, or due to the activity of the halogen atom, causes the other group to enter its structure and cause changes in its properties. Addition is combined with various reagents with its unsaturated bond to develop a new chemical state.
    As for modification, in order to optimize the performance, or increase its stability, or adjust its solubility. To achieve this purpose, it is often necessary to choose suitable reaction conditions and choose delicate reagents. If a catalytic method is used to promote its binding with special groups, change its polarity, and then improve its solubility in different solvents.
    The wonders of chemistry are exploring the changes of these substances in order to achieve the ambition of being used by the world. The reaction and modification of 1,2-dichloro-4- (trifluoromethyl) benzene will continue to be studied in order to obtain new ones.
    Synonyms & Product Names
    1,2-Dichloro-4- (trifluoromethyl) benzene, this substance is used in the field of chemical industry and has a wide range of uses. Its synonyms are also important for academic research.
    Looking at various ancient books, there are many aliases. Some are named after their properties, and some are named according to their structural characteristics. This compound has a unique structure. Chlorine and trifluoromethyl are attached to the benzene ring, which makes its physical and chemical properties unique.
    In the chemical industry, it is often called by different names. This is due to differences in research emphasis and application scenarios. Or starting from the reaction mechanism, or according to the use of the product. Although the name is different, it actually refers to the same substance.
    Knowing its synonyms and trade names is beneficial to chemical research and production. Avoid communication errors and promote technical exchanges. Help researchers accurately search literature, learn about its past research, and lay the foundation for new exploration.
    Safety & Operational Standards
    Safety and Handling Specifications for 1,2-dichloro-4- (trifluoromethyl) benzene
    1,2-dichloro-4- (trifluoromethyl) benzene, this chemical substance is related to safety and handling standards and is of paramount importance.
    At the safe end, it has certain hazards. If this product accidentally touches the skin, or causes skin discomfort, or even burns. Therefore, when operating, wear protective gloves in front of suitable protective clothing. If the skin touches it, rinse with plenty of water immediately and seek medical attention. If it enters the eye, it is even more necessary to rinse with plenty of water immediately and seek medical attention, because it is harmful to the eyes or serious.
    Inhalation is also a serious problem. In poorly ventilated places, its volatile gas can be inhaled into the human body, or cause respiratory tract irritation, causing coughing and asthma. Therefore, in the operation place, it is necessary to have good ventilation, or prepare ventilation equipment. If necessary, wear a gas mask to protect the respiratory system.
    Discuss operating specifications, the first storage. It should be stored in a cool, dry and ventilated place, away from fire and heat sources, to prevent its volatilization from causing danger. Storage containers should be tightly sealed to prevent leakage.
    When operating, professional equipment should be used, and the operator must undergo professional training and be familiar with the operation process. Measurement, transfer and other steps should be stable and accurate to prevent spills and leaks. After the experiment is completed, the remaining 1,2-dichloro-4- (trifluoromethyl) benzene should not be dumped at will, but should be properly handled according to regulations to prevent environmental pollution.
    In short, the safety and operation specifications of 1,2-dichloro-4- (trifluoromethyl) benzene must be strictly followed to ensure the safety of personnel and the environment.
    Application Area
    1,2-Dichloro-4- (trifluoromethyl) benzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help the birth of many specific drugs and heal human diseases. In the realm of material science, it can contribute to the development of new materials, making materials specific, or tougher, or more corrosion-resistant. In the field of pesticide creation, it also has extraordinary performance, which can produce high-efficiency and low-toxicity pesticides, protect agricultural products from pests, and protect the fields from pests. This substance, with its unique nature, blooms brilliantly in various application fields, silently helping the development and progress of mankind, just like an unknown hero, hidden behind the scenes, but with outstanding achievements.
    Research & Development
    In the field of chemical industry, new substances are superimposed, and 1,2-dichloro-4- (trifluoromethyl) benzene is the most important thing for us to study. Its unique nature and many paths can be explored.
    We study its experimental method, observe its reaction rules, and strive for accuracy and clarity. In the process of synthesis, find the best way to increase its yield and improve its purity.
    Looking at its application, it can be used in the fields of medicine and pesticides. In terms of medicine, it may be used as a key intermediate to help create new drugs and solve the suffering of diseases. In terms of pesticides, it may become a high-efficiency active ingredient to protect the health of farmers.
    However, the road to research and development is not smooth. Facing difficulties, such as harsh reaction conditions and cost control, we need to work hard. Only by unremitting research and forging ahead can we achieve the progress of this product, contribute to the prosperity of the chemical industry, and promote its long-term development.
    Toxicity Research
    In recent years, I have paid much attention to the toxicology of 1,2-dichloro-4- (trifluoromethyl) benzene. This substance is chemically different and has special properties. According to various experimental observations, it can cause various changes in living organisms.
    The first time I tried it with insects, I saw that the movement and development of insects were disturbed. After being tested in mice, exposure to this agent for a long time caused damage to the organs of mice, and the liver and kidney functions were abnormal. In other words, it can disrupt the metabolism of cells and block the path of biochemistry.
    It is also tested in the environment. Although it is difficult to eliminate for a long time, it can gradually accumulate with the food chain. If the surrounding water and soil are stained with this thing, it will affect the plants, fish and shrimp. Therefore, its production and consumption should be carefully prevented from spreading, so as to avoid the harm of life and ecological chaos. This is the essence of toxicological research.
    Future Prospects
    1,2-Dichloro-4- (trifluoromethyl) benzene, the future prospect of this substance, is related to our chemical research. Although it is only a specific chemical product at the moment, its potential is like an unbloomed bud, containing endless possibilities.
    Looking at chemical substances, it is often seen in the micro. This 1,2-dichloro-4- (trifluoromethyl) benzene may emerge in the creation of new materials. The rise of new materials can make electronic devices more ingenious and flexible, or make building materials have better performance, weatherproof and durable.
    Furthermore, there are also opportunities in the field of medicine. Or we can use it as a foundation to develop special drugs, solve the pain of everyone, and contribute to health. Although the road ahead is long, we chemical researchers should have the heart to explore, find its light in the unknown, and hope to use it as a guide to open a new chapter in future chemical applications, benefiting all people and achieving a long-term career.
    Where to Buy 1,2-Dichloro-4-(Trifluoromethyl)Benzene in China?
    As a trusted 1,2-Dichloro-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,2-Dichloro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,2-dichloro-4- (trifluoromethyl) benzene?
    1% 2C2 -dibromo-4- (triethoxy) benzene is used in various chemical and pharmaceutical fields.
    In the chemical industry, it is often the key raw material for the synthesis of special polymer materials. Due to its unique chemical structure, it can be integrated into the polymer chain through subtle chemical reactions, giving the material special properties. For example, enhance the heat resistance of the material, so that it can maintain a stable physical form and properties in high temperature environment, and will not be easily deformed or decomposed; improve the corrosion resistance of the material, so that it can resist the attack of various chemical substances and prolong the service life of the material. Therefore, in fields such as aerospace, electronics and electrical appliances that require strict material properties, this compound is often an indispensable component.
    It also plays an important role in the journey of medicine. It is often used as a pharmaceutical intermediate to synthesize drug molecules with specific biological activities. Due to its structural characteristics, it can introduce key chemical groups into drug molecules, affect the interaction between drugs and biological targets, and then adjust the pharmacological activity and pharmacokinetic properties of drugs. For example, it can improve the solubility of drugs, make them more easily absorbed by the human body, and enhance the bioavailability of drugs; or optimize the stability of drugs to ensure that the content and activity of active ingredients are maintained during storage and use. After careful design and synthesis, the drugs derived from it can be used to treat a variety of diseases such as cardiovascular diseases and neurological diseases, and contribute greatly to human health and well-being.
    In summary, 1% 2C2-dibromo-4- (triethoxy) benzene plays a pivotal role in the chemical and pharmaceutical fields, and is the cornerstone of many scientific and technological innovations and industrial development.
    What are the physical properties of 1,2-dichloro-4- (trifluoromethyl) benzene?
    1% 2C2-dideuterium-4- (triethylmethyl) benzene is also an organic compound. Its physical properties are quite unique, and are listed as follows:
    - ** Properties **: Under normal temperature and pressure, it is mostly a colorless and transparent liquid, with a clear view and no visible impurities. This is due to the orderly arrangement of its molecular structure, which makes its appearance appear so characteristic.
    - ** Odor **: It emits a fragrant smell. Although its fragrance is not rich and pungent, it has a unique charm. This smell originates from the chemical atmosphere created by the benzene ring and its substituents.
    - ** Boiling point **: At a certain temperature range, the intermolecular forces, such as van der Waals forces and hydrogen bonds, check and balance each other, so that at a certain temperature, the molecule is energized enough to overcome the liquid phase binding and transform into the gas phase. Specifically, the mass of the molecule, the symmetry of the structure, and the properties of the substituent all affect the boiling point.
    - ** Melting point **: At a certain low temperature range, when the temperature drops to the melting point, the thermal motion of the molecules slows down, close to each other, and arranged according to a specific lattice pattern, thus solidifying. The degree of tight accumulation between molecules and the strength of the interaction play a key role in this process.
    - ** Density **: Compared with water, its density is slightly lower, which reflects the comprehensive effect of the type, number and spatial arrangement of atoms inside the molecule, resulting in a relatively small mass per unit volume.
    - ** Solubility **: In organic solvents, such as ethanol, ether, etc., it exhibits good solubility. Due to the principle of "similar phase dissolution", the compound and organic solvent have similarities in molecular polarity and structure, so it can be miscible with each other. In water, the solubility is poor, because the polarity of water molecules and the non-polarity of the compound molecules are significantly different, and it is difficult for the two to form an effective interaction.
    Is the chemical properties of 1,2-dichloro-4- (trifluoromethyl) benzene stable?
    1% 2C2 -dichloro-4- (triethoxy) benzene has stable physical properties.
    Looking at this compound, in its structure, the chlorine atom and the ethoxy group are connected to the benzene ring. The chlorine atom is electron-absorbing, and the ethoxy group has a donator effect. The interaction between the two maintains the stability of its structure to a certain extent.
    In terms of reactivity, the electron cloud density of the benzene ring varies with the substituent. The chlorine atom decreases the electron cloud density of the adjacent and para-position, and when the electrophilic substitution reaction occurs, the new group more enters the meta-position; the ethoxy donator increases the electron cloud density of the benzene ring, especially the adjacent and para-position, so the electrophilic substitution is also easy to occur here. However, due to the existence of the steric resistance of the disubstituent group, some reactions may be limited, which also maintains its stability to a certain extent.
    Furthermore, from the perspective of the chemical environment, if there is no specific reagent or condition, it is difficult for this compound to react spontaneously at room temperature and pressure. To promote its reaction, specific catalyst, temperature, pressure and other conditions are often required. If there are no such conditions, its molecular structure can be maintained in a relatively stable state.
    However, it should be noted that although its normal state is relatively stable, when encountering strong oxidizing agents, reducing agents, high temperatures or specific catalysts, its stability may be broken, triggering various chemical reactions. Therefore, when storing and using, appropriate protection and operation should be taken according to its characteristics to ensure safety and stability.
    What are the production methods for 1,2-dichloro-4- (trifluoromethyl) benzene?
    The preparation method of 1% 2C2-dichloro-4- (triethoxy methyl) benzene was mostly obtained by complex methods in the ancient Fangjia family, and now I will describe one or two of them.
    First, using benzene as the base, first make the benzene and the halogenating agent meet, according to the appropriate temperature, pressure and catalytic agent, halogenate to produce halogenated benzene. Then, the halogenated benzene is combined with the reagent with triethoxy methyl, during which a suitable reaction medium and catalyst are used to react by condensation to obtain 1% 2C2-dichloro-4- (triethoxy methyl) benzene. In this way, it is necessary to carefully observe the reaction situation, the control of temperature and pressure, and the quality and quantity of the product.
    Second, it also starts with benzene derivatives with specific substituents. First modify its substituents, and introduce ethoxy methyl groups through various reactions such as hydrolysis and esterification. Then use the method of halogenation to conduct chlorine atoms in appropriate positions. The key to this path lies in the order and conditions of each step of the reaction, so that the reaction goes forward and avoids the disturbance of side reactions.
    Or, it can be started from other compounds containing benzene rings and transformed through a series of open-loop, closed-loop, etc. First disassemble the original ring system, introduce the required groups, and then reconstruct the benzene ring through cyclization reaction, and precisely place dichloro and triethoxy methyl based on the specified position. However, this step is cumbersome and requires high skills and conditions.
    Preparation of this compound, various methods have advantages and disadvantages. The setting of reaction conditions, the selection of raw materials, the demand for yield, and the control of impurities are all items that need to be considered in detail. Fang Jia should choose the appropriate method according to his own equipment to achieve the purpose of preparation.
    What are the precautions for using 1,2-dichloro-4- (trifluoromethyl) benzene?
    1% 2C2-dichloro-4- (triethoxymethyl) benzene is an organic compound. During its use, many precautions should not be ignored.
    The first safety protection. This substance may be toxic and irritating, and contact may cause skin and eye discomfort, and even endanger the respiratory tract. Therefore, users must wear appropriate protective equipment, such as protective clothing, gloves and goggles, and operate it in a well-ventilated place to prevent inhalation of its volatile gas. In case of accidental contact, rinse with plenty of water as soon as possible and seek medical attention as appropriate.
    This is the second time to store. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because it is an organic compound, or flammable, it should be stored separately from the oxidant, and must not be mixed to avoid dangerous reactions. And the storage place should be equipped with suitable materials to contain leaks.
    Furthermore, the operating specifications at the time of use. Strictly follow the established process and dosage, and cannot be changed without authorization. After use, properly dispose of the residue, and must not be dumped at will to avoid polluting the environment. During the experiment or production process, accurately control the reaction conditions, such as temperature, pressure and reaction time, to ensure the safe and effective progress of the reaction, and avoid accidents caused by improper conditions or affecting the quality of the product.
    In addition, caution is also required when transporting. Comply with relevant regulations, properly pack, indicate its characteristics and precautions, and hand it over to a qualified transportation unit to ensure safety during transportation. In this way, 1% 2C2-dichloro-4 - (triethoxymethyl) benzene can be used safely and reasonably.