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1,2-Dichloro-4-Fluoro-5-Nitrobenzene

1,2-Dichloro-4-Fluoro-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

759621

Chemical Formula C6H2Cl2FNO2
Molecular Weight 210.0
Appearance Solid
Melting Point 67 - 69 °C
Boiling Point 265.8 °C at 760 mmHg
Density 1.665 g/cm³
Solubility In Water Insoluble
Flash Point 114.6 °C
Vapor Pressure 0.0141 mmHg at 25 °C
Logp 3.38
Refractive Index 1.569

As an accredited 1,2-Dichloro-4-Fluoro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2 - dichloro - 4 - fluoro - 5 - nitrobenzene packaged in 5 - kg containers.
Storage 1,2 - Dichloro - 4 - fluoro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and exposure to air and moisture. Label the storage clearly to avoid misidentification.
Shipping 1,2 - Dichloro - 4 - fluoro - 5 - nitrobenzene is a chemical. Shipments should follow strict hazardous material regulations. It must be properly packaged, labeled, and transported by carriers licensed for such chemicals.
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1,2-Dichloro-4-Fluoro-5-Nitrobenzene 1,2-Dichloro-4-Fluoro-5-Nitrobenzene
General Information
Historical Development
1,2-Dichloro-4-fluoro-5-nitrobenzene is also a chemical substance. Its initiation is also due to diligent research and in-depth research in the field of chemical chemistry, and it is not difficult to achieve. At the beginning, it may be difficult to obtain raw materials, or it may be difficult to refine the techniques, but they are all determined.
It has been a long time since the first generation of researchers. After years, the formula has been reviewed and considered, and the process has been refined. Or new materials can be used to replace the raw materials, or innovative methods can be used to improve the quality. As a result, the quality of this chemical product is good, and the quantity is also increasing.
In today's world, 1,2-dichloro-4-fluoro-5-nitrobenzene is used in the field of production, and it can be used in the field of production and chemical production. Following its development process, the work of researchers cannot be done, and the god of patience is also done by people.
Product Overview
Today, there is a substance named 1,2-dichloro-4-fluoro-5-nitrobenzene. Its shape is colored or crystalline. This is an organic compound with a delicate structure. Chlorine, fluorine, and nitro groups are connected to the benzene ring in a specific order.
This substance is widely used in the field of chemistry. It is often used as a raw material for the synthesis of many fine chemicals, and can be used to create pharmaceuticals, pesticides, and dyes. Its unique structure endows the reaction with unique properties and can initiate a variety of chemical reaction paths.
However, the preparation of this substance requires caution. Because some groups are active, the reaction conditions must be precisely controlled. A slight mistake may lead to impure products or unexpected changes. The research on this compound is of great significance to the development of the chemical industry, paving the way for the creation of more novel and useful things.
Physical & Chemical Properties
1,2-Dichloro-4-fluoro-5-nitrobenzene has unique physicochemical properties. Looking at its shape, it is solid under normal conditions, or light yellow in color, and the texture is uniform and dense. Its melting point is worth paying attention to, including the change of its phase state. After various studies, the melting point is located in a certain range. This value is stable and reproducible, which is one of its characteristics.
When it comes to solubility, it is slightly soluble in common organic solvents, such as ethanol and ether, but it is difficult to dissolve in water. This difference in solubility is due to its molecular structure and polarity. The presence of halogen atoms and nitro groups in its molecules makes the molecular polarity different, and the interaction with water is weak, but the force between organic solvent molecules is appropriate, so it has this state of dissolution.
Furthermore, its chemical activity is also considerable. The strong electron absorption of nitro groups reduces the electron cloud density of benzene rings and increases the activity of halogen atoms. In many chemical reactions, it is easy to cause substitution changes, which can respond to many nucleophiles. This is an important basis for the synthesis of other organic compounds.
Technical Specifications & Labeling
Technical specifications and labeling of 1,2-dichloro-4-fluoro-5-nitrobenzene (commodity parameters)
There is currently 1,2-dichloro-4-fluoro-5-nitrobenzene, and its technical specifications are crucial. Its properties must be pure, with no impurities mixed in it. The melting point should be in a specific range to meet the standard, which is the key to judging its quality.
In terms of labeling, commodity parameters should be clear. On the packaging, it should be marked with prominent words and its name "1,2-dichloro-4-fluoro-5-nitrobenzene", and the chemical formula and molecular weight are also indispensable. The amount of content must be accurately marked so that the user can see it at a glance. In this way, it is necessary to ensure that this product is effective and safe in various applications.
Preparation Method
The method of preparing 1,2-dichloro-4-fluoro-5-nitrobenzene is essential for raw materials and processes. Take fluorobenzene as the base, and first nitrate it with mixed acid to obtain 4-fluoro-5-nitrobenzene. For mixed acids, nitric acid and sulfuric acid are matched in proportion, and temperature control is appropriate. This is the first step of the reaction.
Following chlorine gas chlorination, under a specific catalytic system, the chlorine is substituted at a specific check point of the benzene ring to form 1,2-dichloro-4-fluoro-5-nitrobenzene. The catalytic system needs to be precisely prepared, which is related to the purity and yield of the product.
The whole preparation process requires strict control of temperature, proportion of reactants, and reaction time. After each step of the reaction, the product should be properly handled. After separation and purification, impurities should be removed to obtain high-purity 1,2-dichloro-4-fluoro-5-nitrobenzene. In this way, good quality products can be obtained and used in various chemical fields.
Chemical Reactions & Modifications
There is now a thing named 1,2-dichloro-4-fluoro-5-nitrobenzene. In the field of chemistry, it is our task to explore its reaction and modification.
The reaction of this compound is related to the chemical mechanism. Its structure is unique. Chlorine, fluorine, nitro and other groups coexist and affect each other, resulting in a variable reaction path. To understand its reaction, it is necessary to study the characteristics of the group in detail, such as the strong electron absorption of nitro groups, which changes the electron cloud density of the benzene ring and affects the difficulty of electrophilic and nucleophilic reactions.
As for modification, it is designed to optimize its properties. Or introduce new groups to change their physical and chemical properties to suit various needs. Or adjust the reaction conditions, change the reaction rate and selectivity, and obtain high-purity products.
The road of chemical exploration is long and far-reaching. The reaction and modification of 1,2-dichloro-4-fluoro-5-nitrobenzene should be studied unremitting in a rigorous state, and new gains are expected, which is a building block for the progress of chemistry.
Synonyms & Product Names
1,2-Dichloro-4-fluoro-5-nitrobenzene is also a new product of chemical. The aliases and trade names of this substance are quite important to our research. Its aliases vary, depending on its structure, properties and past titles. If it is called by its chemical structure, or by the name of a similar structure, it is also called by its synthesis path and application scope.
As for the trade name, each business in the market may give its name according to its quality, use, marketing strategy, etc. The chemical research of the ancient times also often has multiple names due to the characteristics of the substance. For example, the ancient pill, the same pill formula, different refiners may have different names. Today's 1,2-dichloro-4-fluoro-5-nitrobenzene is also similar. Knowing its aliases and trade names can be exchanged in the academic community, smooth in market trade, and in chemical research. It is of great benefit.
Safety & Operational Standards
For 1,2-dichloro-4-fluoro-5-nitrobenzene, chemical substances are also used. In experiments and production, safety and operation standards are of paramount importance.
Where this substance is involved, the ventilation of the first place. The cover has a certain volatility. If the ventilation is not smooth, the gas will accumulate, which is easy to cause respiratory discomfort, or even harm health. When placed in a well-ventilated place, so that the air can circulate, and the harmful gas will not dissipate.
When taking it, protective equipment must be worn. Protective gloves must be resistant to chemical corrosion to avoid skin contact with them. Due to skin contamination, or cause allergies, burns, etc. Protective glasses are also indispensable to protect the eyes from accidental splashing.
The operating table should be clean and dry. This object encounters water or certain impurities, or reacts adversely. When operating, the action should be stable and accurate, and do not sprinkle. If there is any spill, clean it immediately according to the specifications. Cover it with an adsorbent material first, then collect it carefully, and then neutralize and treat it with appropriate chemical reagents to ensure environmental safety.
Storage methods are also exquisite. It should be placed in a cool, dry, dark place, away from fire sources and oxidants. Because of its certain chemical activity, it is dangerous to be exposed to heat, fire or mixed with oxidants.
After the experiment or production is completed, all utensils used must be carefully cleaned. Rinse with a specific solvent to remove the residue and ensure that it is safe to use next time.
In general, the safety and operation specifications of 1,2-dichloro-4-fluoro-5-nitrobenzene are related to personal safety, experimentation, and production. It must not be slack, and it must be followed without violation.
Application Area
1,2-Dichloro-4-fluoro-5-nitrobenzene is also an organic compound. Its application field is quite vast. In the field of pharmaceutical synthesis, it is often a key intermediary. With its unique structure, it can be prepared through various chemical reactions to obtain drugs with special curative effects.
It is also indispensable in the process of pesticide creation. Based on this, it can derive efficient and low-toxicity pesticides, protect crops, and drive away pests and diseases.
Furthermore, in the field of materials science, it can participate in the synthesis of special materials, so that materials can obtain unique properties, such as better stability and heat resistance.
All these show that 1,2-dichloro-4-fluoro-5-nitrobenzene has important application value in many fields, which is what should be paid attention to in chemical research and production.
Research & Development
In recent years, I have dedicated myself to the research of 1,2-dichloro-4-fluoro-5-nitrobenzene. This compound has unique properties and has great potential in many fields.
At the beginning, exploring its synthesis path encountered many obstacles. The ratio of raw materials and the control of reaction conditions all need to be carefully considered. After repeated tests, adjust the temperature, duration and catalyst dosage to obtain a better solution.
Then, explore its reactivity. Interact with different reagents, observe the reaction phenomenon, analyze the structure of the product, and understand its reaction law.
Looking to the future, we hope to optimize the synthesis process, reduce costs and increase efficiency. Expand its application scope and play a greater role in medicine, materials and other fields. With time, it will be able to promote the research and development of this compound and contribute to the academic and industrial circles.
Toxicity Research
There is a substance today, named 1,2-dichloro-4-fluoro-5-nitrobenzene. I am a chemical researcher, specializing in the toxicity of this substance. Looking at its structure, chlorine, fluorine, and nitro are all chemically active, or cause toxic changes.
In the past, the method of studying toxicity was mostly tested on animals to observe its physiological changes and judge the strength of the poison. However, although this method is intuitive, it also has shortcomings, considering both humanity and cost.
Today's research also focuses on theoretical analysis, and uses chemical models to deduce the mechanism of toxicity. In 1,2-dichloro-4-fluoro-5-nitrobenzene, the nitro group easily grabs electrons, or disturbs the electron cloud of biomolecules, causing cell dysfunction. And halogen atoms will also change the lipophilicity of molecules, help them enter the biofilm, and increase the possibility of toxicity.
However, toxicity research is not achieved overnight, and multiple methods and accurate judgments are needed to determine the harm of 1,2-dichloro-4-fluoro-5-nitrobenzene to ecology and human body, for protection and application.
Future Prospects
Looking forward to the future, I am looking forward to 1,2-dichloro-4-fluoro-5-nitrobenzene. It has great potential in the field of chemical industry.
Looking at today, although the process is gradually maturing, the road to optimization is still long. In the future, I hope to find more subtle synthesis methods, reduce consumption and improve efficiency, resulting in lower costs and higher quality. And this substance may emerge in the forefront of new material creation, pharmaceutical research and development, etc. With time, new applications will be found and new markets will be opened up. Our scientific researchers should study diligently and explore unremittingly, with the hope of advancing science and technology to help them shine, add brilliance to the industry, and benefit the world.
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Frequently Asked Questions

As a leading 1,2-Dichloro-4-Fluoro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-dichloro-4-fluoro-5-nitrobenzene?
1% 2C2 + - + dioxy + - + 4 + - + river + - + 5 + - + carbonyl indole What is the main degree of use? These four things are involved in "Tiangong Kaiwu", and each has its own use.
The first word is dioxy. Although "Tiangong Kaiwu" does not directly write the name "dioxy", the role of oxygen is looming in the changes of various things. Oxygen is essential for combustion, smelting and other processes. In the book's casting method, metal ore is smelted into pure metal, and fuel is required for combustion and heating. Oxygen supports combustion, so that the fuel can be fully burned, and it can reach high temperature to melt ore and remove impurities to obtain refined gold.
As for the "river" referred to in "4", the book is mostly used for wading in water. The river is the source of irrigation, which is related to farming. The fields depend on the river water to moisturize, and rice and wheat can grow. And the river can be boated, which is the main transportation route. The exchange of materials between the north and the south depends on the river channel, and the transportation of goods by boat, which saves manpower and has a large volume of transportation. It has great contributions to trade and cultural dissemination.
The "carbonyl indole" mentioned in "5", although "Tiangong Kaiwu" does not describe this thing in detail, it is deduced from its chemical properties. Carbonyl indole may have potential uses in dyeing, pharmaceuticals and other processes. Ancient dyeing may use natural substances containing such structures as dyes, which are colored by their special chemical structures. In pharmaceuticals, it may also be used as a raw material for drug processing or participate in the reaction process due to its chemical activity, contributing to drug efficacy.
In short, dioxygen-assisted combustion smelting, river irrigation and transportation, carbonyl indole or dyeing-related pharmaceuticals have important functions in production and life at that time.
What are the physical properties of 1,2-dichloro-4-fluoro-5-nitrobenzene?
1% 2C2 + - + dioxy + - + 4 + - + alkane + - + 5 + - + cyanopyridine are organic compounds, each with unique physical properties.
Dioxy is often colorless and transparent, and has a typical ether odor. It is a liquid at room temperature and pressure. Its boiling point is about 101.1 ° C, and its melting point is -41.4 ° C. It can be miscible with water, alcohol, ether and other solvents. Due to its moderate polarity, it is often used as an excellent solvent and is widely used in organic synthesis and extraction separation.
Alkane is also a colorless and transparent liquid with a special odor. The boiling point is about 34.6 ° C, and the melting point is -116.3 ° C. It is extremely difficult to dissolve in water, but it is easily soluble in organic solvents. Its volatility is very strong, it is a flammable liquid, steam and air can form an explosive mixture, and it is often used as a solvent and reaction intermediate in the chemical industry.
Cyanopyridine, the appearance is white to light yellow crystalline powder, the melting point is about 70-73 ° C, and the boiling point is about 201-204 ° C. Its solubility is different from different solvents, slightly soluble in water, and soluble in organic solvents such as ethanol and ether. Because its molecules contain cyano and pyridine rings, it has unique chemical activity and is widely used in the synthesis of fine chemical products such as medicines, pesticides, and dyes.
These three are of great significance in many fields of the chemical industry. However, due to their different properties, they need to be used according to their characteristics, follow safety regulations, and be properly handled and stored to avoid danger and ensure production safety and efficiency.
What are the chemical properties of 1,2-dichloro-4-fluoro-5-nitrobenzene?
1% 2C2 + - + dioxy + - + 4 + - + Jiang + - + 5 + - + aminobenzene What are the chemical properties? I will answer this question in the classical style of "Tiangong Kaiwu".
Dioxides are active in nature and often have the ability to oxidize. In various chemical reactions, they can be filled with oxidants, which can increase their price state. When encountering flammable substances, or assisting in combustion, it can cause violent changes.
As for 4, if it refers to butane and the like, it belongs to the alkane family. The properties are relatively peaceful, and it is mostly gaseous or liquid at room temperature. It is difficult to dissolve in water, but miscible with organic solvents. At high temperatures or in the presence of catalysts, reactions such as cracking and substitution can occur.
Jiang, the special name for this non-chemical substance, if it is considered in terms of river water, it is a fluid mixed with many things, containing various minerals, microorganisms, etc. Its chemical properties vary from region to region and environment, but it is generally neutral or slightly alkaline.
5, the reference is not detailed, if it is a specific organic number, its properties can only be discussed in detail according to its structure.
For aminobenzene, benzenecycline is alkaline because of the amino group. It can form salts with acids, and because the amino group is the power supply group, the electron cloud density of the benzene ring increases. In the electrophilic substitution reaction, the amino o and para-sites are more susceptible to attack by electrophilic reagents, which is more prone to such reactions than benzene. And aminobenzene has certain reductive properties and can be oxidized, and its oxidation products vary according to conditions.
To sum up, the chemical properties of various substances are different, or active, or peaceful, and each shows its own properties in chemical reactions. It is useful in chemical industry, scientific research and other fields.
What is the production method of 1,2-dichloro-4-fluoro-5-nitrobenzene?
To make diethylene, tetraene, and pentacyanonaphthalene, the method is as follows:
To make diethylene, the main method is often the method of reduction. In a suitable inverter, the catalytic catalyst, such as carbon, etc., containing alkylene or alkyne raw materials, is mixed in a certain proportion to control the reaction degree and reaction force. Generally, the reaction degree is in the middle of the temperature, such as 10 to 100 degrees Celsius. The reaction force is also reduced to the phase value. When the reaction is added, the catalyst promotes the addition of the atom to the mixture and the catalyst, and then the diethyl compound is obtained.
is taken from the tetraene, and more compounds containing hydrogen are produced. Multiple reactions can be used in synthesis, such as Wittig. First, replace the chemical with phosphorus-containing oil to obtain Wittig, and then make it an aldehyde or ketone reaction. Under the influence of the chemical component, the alkenylation reaction is introduced, and carbon-carbon oil is introduced. Multiple steps of this reaction, ingenious reaction way, with tetraethylenes containing tetraethylenes.
The synthesis of pentacyanonaphthalene is often the starting material of naphthalene. Naphthalene can be substituted first to introduce specific functionalities, such as atoms. In the naphthalene substitution, cyanide, such as cyanide, etc., under the action of suitable solution and catalysis, the nucleus is replaced by the anti-chemical, and the atom is replaced by the cyanide group. Multiple substitutions of the anti-chemical, fine control of the anti-chemical components, so that the cyano group is gradually introduced into the naphthalene to obtain pentacyanonaphthalene.
Where this method is used, it is necessary to control the reverse components, and the raw materials are refined. Only by following the principle of synthesis and operating with heart can the required materials be obtained.
What are the precautions for storing and transporting 1,2-dichloro-4-fluoro-5-nitrobenzene?
1% 2C2, dioxy, 4, Jiang, 5, and carbonyl naphthalenes need to pay attention to many matters during storage and transportation.
First, it is related to storage. 1% 2C2, dioxy, 4, Jiang, 5, and carbonyl naphthalenes should be stored in a cool, dry and well-ventilated place. Because they are more sensitive to heat and humidity, high temperature and high humidity environments can easily cause their properties to change, affecting quality and stability. 1% 2C2 If heated, or triggers a chemical reaction, causing the composition to change; dioxy in a humid environment, or deteriorated by moisture.
Second, it involves packaging. It must be packaged with suitable packaging materials. 1% 2C2, dioxy, etc., or corrosive, should be used to resist corrosion packaging, such as special plastic containers, glassware, etc., to prevent packaging damage and leakage. 5. Carbonyl naphthalene has strict requirements on packaging sealing, avoid excessive contact with air, to prevent oxidation and other reactions.
Third, about transportation. Avoid vibration and collision during transportation. Such substances may cause packaging to break due to violent vibration, causing danger. And the transportation tool needs to maintain a suitable temperature and humidity environment. For example, when transporting 1% 2C2, the temperature should be strictly controlled to prevent excessive temperature fluctuations from affecting its performance. 4. During transportation, it is also necessary to ensure environmental stability and avoid external factors.
Fourth, safety protection. Whether it is storage or transportation, staff should take safety precautions. Wear appropriate protective equipment, such as protective gloves, goggles, gas masks, etc. Because 1% 2C2, dioxy, etc. are toxic and irritating, once they come into contact with the human body, or cause harm.
In short, 1% 2C2, dioxy, 4, Jiang, 5, carbonyl naphthalene are stored and transported, from environmental control, packaging selection, transportation operation to personnel protection, every link cannot be ignored, so as to ensure its safety and stability.