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1,2-Dichloro-3-Fluorobenzene

1,2-Dichloro-3-Fluorobenzene

Hongda Chemical

Specifications

HS Code

457747

Chemical Formula C6H3Cl2F
Molar Mass 166.99 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 173 - 174 °C
Melting Point −21.5 °C
Density 1.424 g/cm³ at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point 62 °C
Refractive Index Typically around 1.520 - 1.530 (at 20 °C)

As an accredited 1,2-Dichloro-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2 - Dichloro - 3 - fluorobenzene packaged in 5 - liter containers for chemical use.
Storage 1,2 - Dichloro - 3 - fluorobenzene should be stored in a cool, well - ventilated area away from direct sunlight. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Ensure the storage location has proper fire - fighting and spill - control equipment to handle potential accidents.
Shipping 1,2 - Dichloro - 3 - fluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and exposure during transit.
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1,2-Dichloro-3-Fluorobenzene 1,2-Dichloro-3-Fluorobenzene
General Information
Historical Development
1,2-Dichloro-3-fluorobenzene is also a chemical product. Tracing back to its origin, in the past, chemical sages explored physical properties and studied synthesis methods. At the beginning, the preparation was difficult, and it was only available in a few well-researched rooms. At that time, its use was not widespread, and it was only a resource for academic inquiry.
Years have passed, science and technology have advanced, synthesis techniques have improved, and output has gradually increased. The industrial field began to find its characteristics usable, so its application gradually became more and more complex. It is useful in material creation and pharmaceutical research and development.
Looking at its historical evolution, from a little-known niche to a product that relies heavily on industry and scientific research, it is like a pearl that gradually shines brightly. In the field of chemistry, it blooms its unique brilliance, contributing to human progress and witnessing the prosperity of chemical technology.
Product Overview
1,2-Dichloro-3-fluorobenzene is also an organic compound. It is a colorless to pale yellow liquid with a special odor. The preparation of this substance often requires delicate methods. It can be prepared mostly through a specific halogenation reaction, starting with benzene derivatives, supplemented by suitable catalysts and reaction conditions.
1,2-dichloro-3-fluorobenzene has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate to prepare a variety of drugs, pesticides and functional materials. Due to its unique chemical structure, it endows the related products with special properties and activities. However, when preparing and using it, it is necessary to pay attention to its toxicity and environmental impact, and follow safety regulations and environmental requirements in order to make good use of this compound for the benefit of chemical research and industrial production.
Physical & Chemical Properties
1,2-Dichloro-3-fluorobenzene is an organic compound. Its physical properties, under normal temperature and pressure, are colorless liquids with a special odor. The boiling point is suitable for a certain value, which is related to its volatilization, so it is also characterized. Looking at its density, under specific conditions, its weight can be measured.
Its chemical properties, above the benzene ring, the activity of chlorine and fluorine atoms, are related to many reactions. Or it can combine with other substances by means of nucleophilic substitution, change its structure, and form new substances. And because of its halogen-containing atoms, in a specific environment, it can cause various chemical changes. In the field of organic synthesis, it is a useful raw material for the production of various products, or involves various industries such as medicine and agriculture. With its materialization, it can become a useful result.
Technical Specifications & Labeling
1,2-Dichloro-3-fluorobenzene is also an organic compound. Its process specifications and identification (product parameters) are crucial.
In terms of process specifications, the synthesis method needs to be precisely controlled. The starting material must be pure, and the reaction conditions such as temperature, pressure, and catalyst dosage must be appropriate. The reaction temperature should be stable in a certain range. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow. The pressure should also be moderate to help the reaction go smoothly. The amount of catalyst depends on the reaction rate and yield.
In terms of identification (product parameters), the appearance should be a colorless to light yellow liquid with a specific smell. The purity must reach a certain standard, and the impurity content must be strictly controlled. Physical parameters such as boiling point and melting point are also key markers for identification and quality determination. In this way, the quality and application of 1,2-dichloro-3-fluorobenzene products can be guaranteed.
Preparation Method
1,2-Dichloro-3-fluorobenzene is also an organic compound. The method of its preparation is related to the raw materials and production process, reaction steps and catalytic mechanism, which are important.
The raw materials prepared should be selected as suitable. Or take a specific halogenated aromatic hydrocarbon and add a fluorinated reagent as the starting point. The reaction step is to first meet the halogenated aromatic hydrocarbon and the fluorinating agent under specific conditions, or to control the temperature and pressure in an appropriate solvent. For example, in a closed container, heat up to a suitable degree to allow it to fully react.
The production process needs to be carefully considered. The rate of stirring and the time of reaction are all critical. Uniform stirring can promote the full mixing of raw materials and increase the efficiency of the reaction. Proper time control can ensure the purity of the product.
Catalytic mechanism cannot be ignored. Choosing a suitable catalyst may greatly increase the rate of the reaction. For example, catalysts of some metal salts can reduce the activation energy of the reaction and make the reaction easy to occur. In this way, 1,2-dichloro-3-fluorobenzene can be obtained to meet the needs of all parties.
Chemical Reactions & Modifications
In modern times, chemical refinement has improved, and the technique of organic synthesis has improved day by day. 1,2-Dichloro-3-fluorobenzene is very important in various fields of chemical industry.
Looking at its chemical reaction, in the past, but according to the usual method, the yield and purity are not enough. If you want to improve, you must investigate the mechanism in detail, and study the change of its bonding and the transition of electrons. In the past, it was combined by a certain method, but the secondary should be complicated, and the main product was impure. Later, the method of catalysis was used to select a high-efficiency catalyst, temperature control, pressure and other conditions, and it was effective. Not only did the yield jump, but the product purity was quite good.
As for the change of physical properties, after modification and improvement, its melting, boiling and dissolution properties were all suitable. From this perspective, the study of chemistry focuses on subtlety, gaining insight into the mechanism of reaction, and seeking the changeability of physical properties, so that these products can be better applied to various practical needs and benefit the world.
Synonyms & Product Names
1,2-Dichloro-3-fluorobenzene is also an organic compound. Its synonymous name and the name of the commodity are different in the academic community and the industry.
In the past, the academic community mostly used its chemical structure as the basis, and the naming was accurate, so that its composition and characteristics could be clarified. In the industry, for the convenience of circulation and application, or to take its characteristics, uses, etc., another product name is established.
1,2-dichloro-3-fluorobenzene is widely used in the field of organic synthesis. Due to its unique structure, it can be used as a raw material for many reactions, and then other important compounds can be prepared. Therefore, it is essential for researchers and practitioners to know their synonymous names and commodity names, which can help them travel freely between academia and industry, avoid communication barriers due to differences in terms, and facilitate research and production.
Safety & Operational Standards
1,2-Dichloro-3-fluorobenzene is an important substance in chemical research. Safety and operating standards are of paramount importance between experiments and applications.
This substance has certain chemical activity, or poses a potential danger to the human body and the environment. Therefore, when using it, it is necessary to observe safety measures. The operator needs appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent it from coming into contact with the skin and eyes and causing damage.
In the place of operation, good ventilation must be done. This can allow the volatile vapor to disperse quickly, preventing it from accumulating in the air, reducing the risk of explosion and poisoning. And the operation place should be kept away from fire and heat sources, because it may be flammable, in case of open flames and hot topics, it may cause accidents.
Furthermore, the rules of storage should not be ignored. 1,2-Dichloro-3-fluorobenzene should be placed in a cool, dry and well-ventilated place, away from direct sunlight. And stored separately from oxidants, alkalis, etc., do not mix storage to prevent chemical reactions and endanger safety.
As for waste disposal, it also needs to follow the specifications. Do not dump at will, when handed over to a professional treatment agency, deal with it in an environmentally friendly and safe way, and avoid polluting the environment.
When experimenting with operation, the action should be stable and accurate, and follow the established process. If it is accidentally spilled, emergency measures should be taken immediately, such as absorbing it with inert materials such as sand and vermiculite, and then properly disposing of it.
In this way, strictly abide by safety and operating standards to ensure that the research and application of 1,2-dichloro-3-fluorobenzene is smooth, and it can be protected for people and the environment.
Application Area
1,2-Dichloro-3-fluorobenzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate. Given the special structure of this substance, it can be derived from compounds with unique pharmacological activities through many chemical reactions, which helps to create new drugs and cure various diseases.
In the field of materials science, it is also useful. It can participate in the preparation of polymer materials, giving the material special properties, such as enhancing its stability and corrosion resistance. With its unique chemical properties, it can be cleverly combined with other substances to improve the quality of materials.
In the field of fine chemicals, it is often used as an important raw material. It is used to synthesize various fine chemicals, such as special fragrances, pigments, etc., to add to the richness and diversity of chemical products and increase the breadth and depth of their applications.
Research & Development
In recent years, I have been in the field of chemical industry, specializing in the research of 1,2-dichloro-3-fluorobenzene. Its properties are different, and it is very useful in various chemical processes.
At the beginning, analyze its structure, explore its physicochemical properties, and understand the difficulty of synthesis. The selection of raw materials, the balance of proportions, all need to be carefully planned. Every mistake, the raw materials are wasted, and the products are impure.
However, I did not give up, thinking about it day and night, and trying new ways. After months of work, the process has been improved, the yield has gradually increased, and the purity has also reached a good state.
Also thinking about the prospect of this product, it is widely used in the production of medicine and pesticides. In order to meet the needs of the market, we should expand its production capacity and strive for excellence. I will do my best to promote its development, hope to be in the forest of chemical industry, develop its unique brilliance, add luster to the industry, and benefit the world.
Toxicity Research
1,2-Dichloro-3-fluorobenzene is also a chemical product. It is necessary for me to investigate its toxicity as a chemical researcher.
Looking at this substance, its molecular structure is unique, and the atoms of chlorine and fluorine are attached to the benzene ring. This structure may cause it to have special chemical properties, but it is related to toxicity.
After experiments, taking various organisms as samples, it is tested to be affected by 1,2-dichloro-3-fluorobenzene. See that when it is at high concentrations, it appears to damage biological cells, or interfere with the normal metabolism of cells and damage their physiological functions.
However, the research on toxicity is not limited to this. It is still necessary to test its behavior in the environment, such as diffusion, degradation, etc. Because it may enter the ecology, it affects the biological chain.
Our chemical researchers should investigate its toxicity in depth, for environmental protection and biological safety, do their best to clarify its nature and avoid its harm.
Future Prospects
In today's world, science and technology are changing day by day, and chemical substances are the key to exploring the future for our researchers. The future prospects of this chemical substance, 1,2-dichloro-3-fluorobenzene, are limitless.
This substance has unique chemical properties, or it has emerged in the research and development of new materials. The quality of new materials is related to all areas of people's livelihood. From strong and light aviation materials to sensitive and stable electronic components, it is expected to be rejuvenated by the participation of 1,2-dichloro-3-fluorobenzene.
In the field of medicine, there is also a wide world. It may be the cornerstone of the synthesis of new drugs. With its unique structure, it interacts delicately with biomolecules, finding a new way to overcome difficult diseases.
And with the gradual rise of the concept of green chemistry, the synthesis process of 1,2-dichloro-3-fluorobenzene will also move towards a more environmentally friendly and efficient environment. At that time, its output and quality will increase, benefiting many industries, adding strong impetus to future development, and leading our generation to endless possibilities.
Where to Buy 1,2-Dichloro-3-Fluorobenzene in China?
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Frequently Asked Questions

As a leading 1,2-Dichloro-3-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-dichloro-3-fluorobenzene?
1,2-Dichloro-3-butene, its main uses are as follows:
This substance is very important in the field of organic synthesis. It can be used as a key intermediate to prepare many organic compounds with specific structures and properties. For example, in the synthesis of fine chemical products, complex organic molecular structures can be constructed through a series of chemical reactions, laying the foundation for the synthesis of drugs, fragrances, etc.
In the field of materials science, it can be used to participate in polymerization reactions to prepare polymer materials with special properties. Through clever design of reaction conditions and comonomers, materials are endowed with properties such as excellent chemical resistance and good mechanical properties, and play a key role in material applications in special fields.
In the field of pesticide synthesis, 1,2-dichloro-3-butene also has a place. It can be used as a starting material for the synthesis of some high-efficiency and low-toxicity pesticides. After chemical modification and reaction, pesticide products with specific killing effects on pests and environmental friendliness can be prepared, providing a powerful means for agricultural pest control.
However, it should be noted that 1,2-dichloro-3-butene has certain toxicity and irritation. During use, storage and transportation, relevant safety regulations and operating procedures should be strictly followed to ensure the safety of personnel and the environment is not polluted. When performing various reactions using it as a raw material, it is also necessary to precisely control the reaction conditions to improve the reaction efficiency and product purity.
What are the physical properties of 1,2-dichloro-3-fluorobenzene?
1% 2C2-dichloro-3-butene is an organic compound, and its physical properties are quite unique. Although it is difficult to find direct records in ancient books, it can be analyzed from the perspective of "Tiangong Kaiwu".
This substance is mostly in a liquid state at room temperature, like smart water, but not as clear and simple as water. Its color may be colorless, just like transparent glaze, pure but without variegation; or slightly yellowish, like the shimmer of early morning light, vague and elegant. Looking at its appearance, it is like a calm lake surface, without waves and water, but the chemical activity contained in it is not as quiet as the surface.
Smelling its smell, it must give off a special smell, or it may be irritating, like a spicy smell, rushing straight into the nose, making people instantly alert; or it may have a fragrant charm, but it is not the sweet and greasy of traditional flowers, but a unique organic fragrance, which attracts people to explore the mysteries.
The boiling point and melting point of 1% 2C2-dichloro-3-butene are crucial for the identification and separation of substances. Its boiling point or in a specific temperature range, when heated to this point, it is like ice melting into water, sublimating from liquid to gaseous state, realizing the transformation of phase state; the melting point also has its fixed value, like a limit, when the temperature drops below, it changes from flowing state to solid state, like water condensing into ice, and the shape changes significantly.
Its density may be different compared to water. If it is placed in the same place as water, or floating on water, it looks like a light boat on the lake surface; or sinking underwater, like a boulder falling into a deep pool, this property also provides a key basis for identification and separation.
In terms of solubility, it varies in different solvents. In organic solvents, such as salt, it is easily dissolved and fused with water; in water, or like oil floating in water, it is difficult to blend, which is of great significance in chemical preparation and purification.
Is the chemical properties of 1,2-dichloro-3-fluorobenzene stable?
1% 2C2-dichloro-3-chloropropene This substance is chemically unstable.
1% 2C2-dichloro-3-chloropropene The molecular structure contains multiple chlorine atoms, and the carbon-chlorine bond has a certain polarity. From the perspective of reactivity, it is prone to attack by nucleophiles. In an alkaline environment, chlorine atoms are easily replaced by nucleophilic groups such as hydroxyl groups, and nucleophilic substitution reactions occur. For example, in aqueous sodium hydroxide solutions, compounds containing hydroxyl groups may be gradually formed.
Moreover, there are unsaturated bonds in the molecules of this substance, namely carbon-carbon double bonds. Carbon-carbon double bonds are electron-rich and vulnerable to attack by electrophilic reagents, resulting in addition reactions. Like when it meets bromine water, the double bond will be added to bromine, causing the bromine water to fade. Under light conditions, the chlorine atoms in its molecules may also undergo free radical reactions, and the chlorine atoms are separated from the molecules to form chlorine free radicals, which in turn triggers a series of complex reactions.
In addition, 1% 2C2-dichloro-3-chloropropene may slowly undergo the above reactions and deteriorate if it comes into contact with air, moisture or certain impurities during storage. Therefore, it needs to be properly stored. It is usually sealed in a cool, dry place away from fire sources and oxidants to maintain its chemical stability as much as possible. However, due to its own structural characteristics, it is difficult to maintain an absolutely stable state for a long time.
What are the production methods of 1,2-dichloro-3-fluorobenzene?
The preparation methods of 1% 2C2-dideuterium-3-deuterium-substituted propylene are generally as follows:
One is to use propylene as the starting material, through halogenation reaction, such as with bromine under the action of light or initiator, 1-bromo-2-propylene is generated, and then deuterated reagents, such as deuterated alcohol solution of deuterated alcohol potassium, can introduce deuterium atoms, and through subsequent reaction steps, the target product can be obtained. The reaction mechanism lies in the nucleophilic substitution of halogen atoms, the negative ions of deuterated reagents attack the alpha-carbon of halogenated hydrocarbons, and the halogen ions leave to realize the introduction of deuterium atoms.
The second can be started from the corresponding enol ether. The enol ether and the deuterated acid undergo an addition reaction to form an intermediate. After the elimination reaction, the corresponding alcohol is removed to obtain an olefin containing deuterium. In this process, the double bond of the enol ether is nucleophilic, and it is added to the proton (deuterium) of the deuterated acid. Then under alkaline conditions, the alcohol part is eliminated to construct the target olefin structure.
The third is to use alkynes as raw materials and pass the method of partial reduction. If 1-propane is used as the starting point, in the presence of a specific catalyst, such as Lindra catalyst, deuterium gas is used for partial reduction, and alkynes can be selectively reduced to cis-olefins to achieve the introduction of deuterium atoms in the olefin structure, thereby obtaining 1% 2C2-dideuterium-3-deuterated propene. This reaction is based on the selectivity of the catalyst for the reduction of alkynes, and the reaction is controlled to stay in the olefin stage.
All these methods have their own advantages and disadvantages. In actual preparation, the appropriate method should be carefully selected according to the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.
What are the precautions for storing and transporting 1,2-dichloro-3-fluorobenzene?
1% 2C2-dichloro-3-chloropropene should be used with caution in all matters of storage and transportation. Its nature is strong and dangerous, and if it is not careful, it will cause disaster.
When storing, the place must be carefully selected. It must be placed in a cool and ventilated place, away from fire and heat sources. Because it is flammable, it will burn in case of fire, and the fire is difficult to control, which is easy to cause catastrophe. The temperature of the warehouse should be controlled in a suitable area to prevent its properties from mutating due to high temperature and causing danger. And the humidity of the warehouse should not be ignored. If the humidity is too high, it may react with water vapor, which will damage its quality and increase the risk.
Its container must be strong and sealed. This is the key to preventing it from leaking. If there is a leak, the poisonous gas will escape, which will harm people's health, and if it is light, it will be uncomfortable, and if it is heavy, it will endanger life; if it is in the environment, it will pollute its water, soil, and air, and the ecological balance will be broken.
When transporting, the person handling it must be professional and cautious. Load lightly and unload lightly, and do not do it brutally to prevent damage to the container and leakage. The tools used for transportation should also be carefully inspected to ensure that there are no hidden dangers.
Transportation route planning is also a priority. Avoid places with dense crowds, water sources and other key hazards. If it leaks on the way, in the crowd, the poisonous gas will spread, and all living beings will be harmed; in the water source, the water quality
Furthermore, transportation and storage must be carried out in accordance with laws and regulations. Carry the safety technical manual and chemical label of this object for inspection, to identify its hazards, and to remind people. In this way, the storage and transportation are safe and the disaster is avoided.