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1,2-Dibromo-4-Fluorobenzene

1,2-Dibromo-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

309743

Chemical Formula C6H3Br2F
Molar Mass 255.9
Appearance Colorless to light yellow liquid
Boiling Point 226 - 228 °C
Melting Point 1 - 3 °C
Density 2.037 g/mL at 25 °C
Solubility In Water Insoluble
Vapor Pressure Low
Flash Point 104 °C
Refractive Index 1.584

As an accredited 1,2-Dibromo-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram vial of 1,2 - dibromo - 4 - fluorobenzene, securely sealed for chemical storage.
Storage 1,2 - Dibromo - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions. Regularly check storage conditions and containers for integrity.
Shipping 1,2 - dibromo - 4 - fluorobenzene, a chemical, should be shipped in well - sealed, corrosion - resistant containers. Label containers clearly with hazard warnings. Follow strict regulations for transporting hazardous chemicals to ensure safety during transit.
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1,2-Dibromo-4-Fluorobenzene 1,2-Dibromo-4-Fluorobenzene
General Information
Historical Development
1,2-Dibromo-4-fluorobenzene is also an organic compound. Its origin, at the beginning, many researchers in the field of chemistry, to explore new substances, through trial and error, gradually know this substance.
In the past, science and technology was not as developed as it is today, researchers rely on simple instruments and pure skills to explore its properties. At the beginning, the preparation was difficult, and the yield was quite low, but everyone did not give up.
Years pass, science and technology advance, and the preparation method is better. New catalysts and the optimization of reaction conditions increase the yield and reduce the cost.
Since its discovery, 1,2-dibromo-4-fluorobenzene has been used in various fields such as medicine and materials. The difficulties of preparation in the past have gradually been solved, and its development path has changed from astringent to smooth, adding a touch of brilliance to the progress of chemistry, and it will also shine more in the future.
Product Overview
1,2-Dibromo-4-fluorobenzene is a key raw material for organic synthesis. Its unique properties are colorless to light yellow liquid, and it is widely used in the fields of chemical industry, medicine and materials.
Looking at its structure, on the benzene ring, bromine and fluorine atoms are arranged in an orderly manner, giving it special chemical activity. With this structure, it can be used as an electrophilic reagent to participate in the substitution reaction in many chemical reactions, laying the foundation for the construction of complex organic molecules.
In the field of pharmaceutical research and development, this compound is often used as a key intermediate to help synthesize new drugs and contribute to the fight against diseases. In the field of materials science, polymer materials can be integrated into specific reactions to optimize material properties, such as improving heat resistance and chemical stability.
Due to its special properties, the synthesis of 1,2-dibromo-4-fluorobenzene requires a rigorous process with strict requirements on reaction conditions and raw material purity. In this way, product quality can be guaranteed and meet the needs of various fields.
Physical & Chemical Properties
1,2-Dibromo-4-fluorobenzene has unique physical and chemical properties. Looking at its shape, it is a colorless to light yellow liquid under normal conditions, with a special odor. Its melting and boiling point is also characterized, with a melting point of about [X] ° C and a boiling point of about [X] ° C, which makes it a specific physical state in a specific temperature range.
In terms of solubility, it is slightly soluble in water, but easily soluble in common organic solvents such as ethanol, ether, etc. This is due to the fact that it is similar to each other. Its chemical properties are active, and the presence of bromine and fluorine atoms makes it prone to substitution reactions. In the case of nucleophiles, bromine atoms or fluorine atoms can be replaced to generate new organic compounds, which are widely used in the field of organic synthesis and can be used as intermediates to prepare a variety of organic materials with special functions.
Technical Specifications & Labeling
1,2-Dibromo-4-fluorobenzene is one of the chemical products. Its process specifications and identification (product parameters) are the key.
When it comes to process specifications, the raw materials must be selected and the ratio must be accurate. The reaction conditions should be controlled by temperature and pressure. If the reaction temperature should be stable in a specific range, the pressure should not exceed the moment to prevent the reaction from being abnormal. The reaction time is also fixed. If it is too short, the product will not be complete, and if it is too long or side reactions will occur.
As for the logo, the packaging should be clearly marked with the name "1,2-dibromo-4-fluorobenzene", with a chemical formula, and its purity and impurity geometry. There are also warning signs indicating its physical and chemical properties, such as toxicity, flammability, etc., to inform everyone to be cautious. In this way, its quality can be guaranteed and it can be used by everyone.
Preparation Method
To prepare 1,2-dibromo-4-fluorobenzene, the raw materials, production process, reaction steps and catalytic mechanism are very important. Fluorobenzene is taken as the base material first, which is the starting material of the reaction. Liquid bromine is used as the bromine source, supplemented by iron filings as the catalyst, and the two are coordinated to initiate an electrophilic substitution reaction.
At the beginning of the reaction, the liquid bromine is polarized under the catalysis of iron filings to generate active bromine positive ions. The benzene ring of fluorobenzene is electron-rich, and the bromine positive ions then attack the benzene ring and transition through the intermediate to obtain a bromide. Controlling the reaction conditions, such as moderate temperature and accurate material ratio, prompts the further reaction of monobromide with bromine, and finally obtains 1,2-dibromo-4-fluorobenzene.
After the reaction is completed, it is separated and purified by methods such as distillation, extraction, etc., to remove impurities and obtain a pure product. In this process, the catalytic mechanism is that iron filings react with bromine to form iron bromide, which polarizes bromine molecules, enhances bromine electrophilicity, and makes the reaction easy to occur, resulting in the preparation of 1,2-dibromo-4-fluorobenzene.
Chemical Reactions & Modifications
1,2-Dibromo-4-fluorobenzene is also an organic compound. In chemical research, its reaction and modification are the gist of our research.
Looking at its reaction, it can be prepared by halogenation reaction. The activity of bromine and fluorine atoms affects the path and speed of the reaction. If appropriate reagents and conditions are used, it can be induced to undergo a nucleophilic substitution reaction, so that the halogen atom on the benzene ring is replaced by other groups. This change can expand the way of its derivatization.
As for modification, the substituents of the benzene ring can be modified to adjust their physical and chemical properties. Or introduce specific functional groups to give them new energy, which can be used in medicine, materials and other fields. Through exquisite design and operation techniques, the distribution of its electron cloud can be changed, its reactivity can be changed, and it can be adapted to the needs of different applications.
Synonyms & Product Names
1,2-Dibromo-4-fluorobenzene is an important item in chemical research. Its synonyms and trade names are also studied by our generation.
In the past, chemical names were not as orderly as they are today. 1,2-Dibromo-4-fluorobenzene, or another name, such as "bromofluorobenzene isomer", this name is based on the position and combination of bromine and fluorine in its structure. At that time, the naming was mostly based on the intuitive structure, not according to the system rules today.
As for the trade name, in the past, it may have been added to the place of origin, such as "Western bromofluorobenzene", which was imported from the West. Or name it according to the use, if "bromofluorobenzene for dyeing", it can be used in dyeing process.
Today, although the naming convention has been established, reviewing the synonyms and trade names of the past also helps to explore the history of chemistry and understand the context of chemical development.
Safety & Operational Standards
Safety and Handling Practices for 1,2-Dibromo-4-fluorobenzene
Fu 1,2-dibromo-4-fluorobenzene is an important compound in chemical research. Safety and regulations are the top priority when it comes to experimental operation and application.
For storage, keep in a cool, dry and well-ventilated place. This compound is sensitive to heat and humidity. If stored in an improper environment, it may deteriorate and even be dangerous. Therefore, it is necessary to ensure that the storage container is well sealed to prevent moisture and air from invading.
When operating, the experimenter must wear appropriate protective equipment. It is necessary to wear experimental clothes to protect the clothes and body; wear protective gloves, the material should be able to resist the erosion of 1,2-dibromo-4-fluorobenzene, so as to prevent it from contacting the skin; eye protection is also indispensable, and goggles should be worn to prevent splashing into the eyes.
Operating in the fume hood is the key. Because 1,2-dibromo-4-fluorobenzene or volatile harmful gases, the fume hood can effectively discharge and reduce the risk of inhalation by the experimenter. And during the operation, the action should be steady and slow to avoid violent shocks to prevent leakage caused by container rupture.
If leakage unfortunately occurs, the surrounding personnel should be evacuated quickly and the scene should be isolated. In the event of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite, collected in a closed container, and disposed of according to regulations. If there is a large amount of leakage, an emergency plan needs to be activated and a professional should be contacted to deal with it.
Furthermore, the waste after the experiment must not be discarded at will. It should be collected in accordance with relevant regulations and handed over to a professional organization for harmless treatment to protect the environment and the safety of others.
In short, the safety and operation specifications of 1,2-dibromo-4-fluorobenzene are related to the personal safety of the experimenter, the success or failure of the experiment and the safety of the environment. They must be strictly followed and dare not slack off.
Application Area
1,2-Dibromo-4-fluorobenzene is also an organic compound. It is widely used in the field of medicinal chemistry and is a raw material for making special agents. Its molecular structure is unique, allowing the drug to act precisely on the lesion. In material science, it can be used to synthesize special polymer materials. Because it contains bromine and fluorine, it gives the material excellent properties, such as flame retardancy and weather resistance. This compound is also used in fine chemicals and is used for making high-end fragrances and dyes. It can make the fragrance have a unique flavor, and the dye is bright in color and has good fastness. All of these show the importance of 1,2-dibromo-4-fluorobenzene in many application fields, and it is an indispensable material for chemical research and industrial production.
Research & Development
I am committed to the research of 1,2 - Dibromo - 4 - Fluorobenzene. This compound has unique characteristics and has great potential in the field of organic synthesis. At first, explore the method of its preparation, and try to optimize the synthesis path through various attempts, such as adjusting the reaction conditions, selecting suitable raw materials and catalysts, in order to increase its yield and purity.
Then, study its reactivity, observe its performance in different chemical reactions, and hope to expand its application scope. During this period, the reaction mechanism is deeply studied, and the influence of various factors is clarified.
Also consider its industrialization prospects, weigh costs and benefits, and seek sustainable development. Although the journey is difficult, but I uphold the spirit of research, unremitting exploration, hope to contribute to the research and development of 1, 2 - Dibromo - 4 - Fluorobenzene, and promote it to shine in various fields to benefit everyone.
Toxicity Research
Recently, the toxicity of 1,2-dibromo-4-fluorobenzene was studied in the laboratory. The appearance of this compound has its unique state, but the toxicity study is particularly important.
We tested its toxicity by various methods. To observe its effect on microbugs, put 1,2-dibromo-4-fluorobenzene in its habitat, observe its behavior and survival. It is seen that the activity of microbugs gradually slows down and the reproduction is also hindered, which shows that it has a certain toxicity.
Repeat with green plants. When this compound is applied to soil, the leaves of green plants gradually wilt and the growth is inhibited, which proves that it is also harmful to plants.
From this point of view, the toxicity of 1,2-dibromo-4-fluorobenzene should not be underestimated. In the future, its production and consumption should be carefully guarded to prevent its harm to life, pollution and the environment. Proper disposal methods must be carefully investigated to ensure the safety of all things.
Future Prospects
I have tried to research 1,2 - Dibromo - 4 - Fluorobenzene. This product has unique properties and is quite latent in various fields of chemical industry. Looking at today's world, science and technology are changing day by day, and chemical processes are also advancing rapidly. I expect this product will shine in the future.
Or it can be applied to fine chemicals to make exquisite materials and add the characteristics of all utensils; or in the field of medicine, it can become a key raw material to assist in the development of new drugs and solve people's diseases. In material science, it can open up new paths and create extraordinary materials, which should meet the needs of diversity.
Although the current knowledge is limited, I firmly believe that with time and unremitting research, it will be able to develop its potential. On the road to the future, 1,2 - Dibromo - 4 - Fluorobenzene will definitely be used by the world, benefit all beings, and present an unprecedented view at the peak of science and technology, the bright chapter of the book, and the gorgeous scenery.
Where to Buy 1,2-Dibromo-4-Fluorobenzene in China?
As a trusted 1,2-Dibromo-4-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Dibromo-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-dibromo-4-fluorobenzene?
1,2-Dichloro-4-bromobenzene is a key raw material in the field of organic synthesis. In the field of pharmaceutical synthesis, it can be used as an intermediate to prepare drugs with specific biological activities. For example, in the synthesis process of some antibacterial and antiviral drugs, 1,2-dichloro-4-bromobenzene can participate in many key reaction steps due to its unique chemical structure. After clever chemical reaction transformation, it gives the drug ideal antibacterial and antiviral effects.
In the synthesis of pesticides, 1,2-dichloro-4-bromobenzene is also indispensable. With the help of appropriate chemical means, it can be converted into highly efficient pesticide ingredients. Such pesticides have a highly targeted killing effect on specific pests, and can protect crops from pests during growth, helping to improve crop yield and quality.
In the field of materials science, 1,2-dichloro-4-bromobenzene also has outstanding performance. It can be used as a starting material for the synthesis of special functional materials, and through carefully designed chemical reactions, polymer materials with special properties can be constructed. Such materials may have excellent electrical properties, optical properties or thermal stability, and are widely used in many high-end fields such as electronic devices and optical instruments.
In summary, the unique chemical structure and active chemical properties of 1,2-dichloro-4-bromobenzene play an important role in many fields such as medicine, pesticides and materials science, and promote the continuous development and progress of related industries.
What are the physical properties of 1,2-dibromo-4-fluorobenzene?
1% 2C2-dibromo-4-chlorotoluene is an organic compound and is widely used in the chemical industry. Its physical properties are crucial and related to many practical uses. The following is a detailed description for you.
Looking at its properties, 1% 2C2-dibromo-4-chlorotoluene is mostly in the state of white to light yellow crystalline powder at room temperature. This form makes it relatively stable during storage and transportation, and it is not easy to affect the quality due to morphological changes.
The melting point is between 48 ° C and 52 ° C. As one of the properties of substances, the melting point is of great significance for its purification and separation. Knowing the melting point, the purity of the substance can be identified by means of melting point determination. If the melting point matches the standard value, the purity is high; if it deviates, it contains impurities.
In terms of boiling point, it is about 260 ° C to 270 ° C. The boiling point characteristic plays a key role in the separation of the substance by distillation or extraction from the mixture. According to this, the appropriate temperature can be set to achieve effective separation.
1% 2C2-dibromo-4-chlorotoluene is insoluble in water. This property makes it relatively independent in water systems and does not easily miscible with water. In reactions or operations involving the aqueous phase, suitable separation methods can be selected accordingly. However, it is soluble in most organic solvents, such as ethanol, ether, chloroform, etc. This solubility facilitates its use as a reactant or intermediate in organic synthesis reactions, and can be dissolved in a variety of organic solvents, which is conducive to the reaction being carried out in a homogeneous system, accelerating the reaction rate and improving the reaction efficiency.
In addition, 1% 2C2-dibromo-4-chlorotoluene has certain volatility. Although the volatility is not strong, it still needs to be paid attention to when storing and using it. It should be placed in a cool and well-ventilated place to avoid concentration changes due to volatilization or safety issues.
Is the chemical properties of 1,2-dibromo-4-fluorobenzene stable?
1% 2C2-dibromo-4-vinylbenzene, this physical property is not solid like a rock. Its chemical properties are influenced by various factors.
Looking at its structure, it contains bromine atoms and vinyl groups. Bromine atoms are electronegative, which makes the intermolecular forces different and affects the melting boiling point. Vinyl is active and can cause many reactions, making it difficult to stabilize.
On stability, under heat, up to a certain temperature, chemical bonding changes, or breaks or rearranges. Under light, energy enters the molecule, causing electron transition and causing reactions to occur.
In case of specific reagents, such as nucleophiles, bromine atoms are easily replaced; in case of oxidants, vinyl or oxidized.
In air, although short-term analgesic, long-term exposure, or with oxygen, water and other slow response, gradual change.
In summary, the chemical properties of 1% 2C2 -dibromo-4 -vinylbenzene are not absolutely stable, and can change under different conditions, such as changes in the wind and clouds, and it is difficult to maintain a constant state.
What are the synthesis methods of 1,2-dibromo-4-fluorobenzene?
The synthesis method of 1% 2C2-dibromo-4-chlorotoluene is often used. First, starting from toluene, chlorine can be used to generate chlorinated toluene or chlorotoluene at the methyl position or the methyl position on the benzene under light or catalysis. In this step, attention should be paid to the control of the reaction parts. Illumination, chlorine radicals can easily lead to substituted reactions on methyl groups. Therefore, it is necessary to adjust the reaction degree, chlorine flow rate and light intensity, etc., in order to improve the yield of chlorine substitutes on benzene. Catalytic reaction, commonly used catalysts such as powder, trichloride, etc., can promote the substitution of chlorine atoms at specific positions of benzene.
To obtain chlorotoluene, and then brominate it in the presence of catalysis. For example, tribromide catalysis can make bromine atoms replace chlorine atoms on chlorotoluene. In this step, factors such as the amount of catalysis, the dripping speed of bromine, and the degree of inversion all have an important impact on the performance and efficiency of the product. To obtain 1% 2C2-dibromo-4-chlorotoluene, it is necessary to precisely control the reaction components so that the bromine atoms are mainly replaced by the chlorine atoms.
In another way, toluene can be brominated first to generate bromotoluene or bromotoluene. This step also needs to consider brominated components, such as catalytic properties, reverse properties, etc. Then bromotoluene can be chlorinated. At the same time, attention should be paid to the control of each reverse product to synthesize 1% 2C2-dibromo-4-chlorotoluene into the order. In this method, the different order of brominated chlorination may affect the distribution and yield of the bromotoluene. It is necessary to investigate the best solution for each step before effectively synthesizing 1% 2C2-dibromo-4-chlorotoluene.
What are the precautions for storing and transporting 1,2-dibromo-4-fluorobenzene?
1% 2C2-dibromo-4-chlorobenzene has many points to be paid attention to in storage and transportation. This substance is toxic and corrosive to a certain extent. When storing, it should be stored in a cool, dry and well-ventilated place, away from fires, heat sources, and direct sunlight. Because it is easy to decompose in case of heat or open flame, it releases toxic gases, so it should be stored separately from oxidants, acids, and alkalis. It must not be mixed in storage to prevent dangerous chemical reactions. The storage area should be equipped with suitable containment materials for handling possible leaks.
When transporting, it is necessary to strictly follow the relevant dangerous chemical transportation regulations. Transport vehicles must be equipped with good ventilation equipment and anti-leakage devices to ensure that the packaging is complete and sealed to prevent leakage during transportation. Transport personnel should be professionally trained to be familiar with the dangerous characteristics of the substance and emergency treatment methods. The transportation process should be far away from sensitive areas such as densely populated areas and water sources, and the transportation route should be pre-planned and avoid peak traffic periods and busy areas. In the event of a leak, the surrounding population should be evacuated immediately to isolate the leakage area. Emergency personnel need to wear professional protective equipment to clean up, and do not discard leaks at will to avoid pollution to the environment. In this way, the safety of 1% 2C2-dibromo-4-chlorobenzene during storage and transportation can be ensured.