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1-(2-Bromoethyl)-4-Fluoro-Benzene

1-(2-Bromoethyl)-4-Fluoro-Benzene

Hongda Chemical

Specifications

HS Code

366831

Chemical Formula C8H8BrF
Molecular Weight 203.05
Appearance Colorless to light yellow liquid
Boiling Point Approximately 210 - 212°C
Density 1.49 g/cm³ (approximate)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, etc.
Flash Point Around 86°C
Refractive Index 1.523 - 1.525 (approximate)

As an accredited 1-(2-Bromoethyl)-4-Fluoro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1-(2 - bromoethyl)-4 - fluoro - benzene in sealed, labeled chemical vial.
Storage 1-(2 - bromoethyl)-4 - fluoro - benzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping 1-(2 - bromoethyl)-4 - fluoro - benzene is shipped in accordance with chemical transport regulations. Packed in suitable, leak - proof containers, it's transported with proper labeling and safety precautions to ensure secure delivery.
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1-(2-Bromoethyl)-4-Fluoro-Benzene 1-(2-Bromoethyl)-4-Fluoro-Benzene
General Information
Historical Development
1- (2-bromoethyl) -4-fluorobenzene is also an organic compound. In the past, the beginning of organic chemistry was not long, and the study of this compound was still shallow. Chemists only knew its basic constituent elements at the beginning, but did not know much about its delicate structure and strange properties.
With the passage of time, chemical technology has become more and more delicate. There are more and more ways to analyze its molecular structure. Spectroscopy and diffraction techniques are all powerful tools, allowing chemists to see the secrets of 1- (2-bromoethyl) -4-fluorobenzene molecules. Its behavior in the reaction is also gradually clarified. Chemists have insight into the laws of its phase transformation with other substances, and can use various reactions to control and change it.
Today, 1- (2-bromoethyl) -4-fluorobenzene has emerged in the fields of materials, medicine, and so on. From the ignorance of the past to the wide application today, it is a testament to the continuous improvement of chemical research, and its future is expected to be broader.
Product Overview
Today, there is a substance named 1- (2-bromoethyl) -4-fluorobenzene. It is an organic compound that has attracted much attention in the field of chemical research. This substance has a unique structure. On the benzene ring, fluorine atoms and (2-bromoethyl) each have one place, and the layout is consistent.
Looking at its physical properties, at room temperature, it may be liquid, colored or nearly colorless, and has a certain volatility. Its chemical properties are active, and both bromine and fluorine atoms are reactive. Bromine atoms can be replaced by other functional groups through nucleophilic substitution reactions; fluorine atoms can affect the electron cloud distribution of molecules, thereby affecting their reaction tendencies.
This compound has potential applications in material synthesis, drug development, etc. In material synthesis, polymer materials with special structures can be constructed by virtue of their reactivity; in the field of drug development, new drugs may be developed based on their structural characteristics. In short, 1- (2-bromoethyl) -4-fluorobenzene is a compound of considerable research value.
Physical & Chemical Properties
1- (2-bromoethyl) -4 -fluorobenzene is an important substance in chemical research. Its physical and chemical properties are worth exploring. Looking at its properties, it may be a colorless to pale yellow liquid at room temperature, with a special odor. The genera of its boiling point and melting point are related to the stability and volatility of the substance. The boiling point is about a specific temperature range, which is the key node of gasification and reflects the strength of intermolecular forces. The melting point is also of characterization significance, which is related to the transformation of solid and liquid states.
In terms of solubility, it may have a certain solubility in organic solvents such as ethanol and ether. This characteristic is greatly affected by the selection of reaction medium, separation and purification steps. Due to the presence of bromine and fluorine atoms, the electron cloud density of the benzene ring changes, which easily triggers reactions such as nucleophilic substitution, providing a path for the synthesis of novel compounds, and has great potential in the field of organic synthesis.
Technical Specifications & Labeling
1- (2-bromoethyl) -4-fluorobenzene, the process specification and identification (product parameters) of this substance are the key. The preparation process needs to follow a precise process, starting from the selection of raw materials and going through multiple careful reaction steps, each step is related to the purity and quality of the product. The reaction conditions such as temperature, pressure, and catalyst dosage are strictly limited, and a slight deviation may cause the product to be impure.
In terms of identification, its chemical name, molecular formula, and molecular weight should be clearly marked, which are basic information. Its physical properties, such as appearance, melting point, boiling point, and density, should also be detailed. More emphasis should be placed on warning of its chemical hazards, such as toxicity and corrosiveness, so that users can operate with caution. Strict adherence to process specifications and accurate marking can ensure the safety and efficiency of this product in scientific research and industrial applications.
Preparation Method
The method of making 1- (2-bromoethyl) -4-fluorobenzene is the first raw material and production process. The raw material selection should be pure and suitable, such as fluorobenzene and 1,2-dibromoethane as the base. In the production process, the reaction steps are rigorous and orderly.
First, fluorobenzene and 1,2-dibromoethane react under a specific temperature and pressure environment with the help of a catalyst. Temperature control is moderate, not high or low, and pressure needs to be stable, which is the key.
In the reaction, there is a catalytic mechanism. With a specific catalyst, the chemical bond between the two is broken and a new bond is formed, so 1- (2-bromoethyl) -4-fluorobenzene is obtained.
In this way, the raw material is selected and the process follows the rules. The reaction steps are clear and the catalytic mechanism is smooth, so that the high-quality 1- (2-bromoethyl) -4-fluorobenzene can be obtained.
Chemical Reactions & Modifications
The reaction and modification of a chemical substance is related to the compound 1- (2-bromoethyl) -4-fluorobenzene. I tried to study this, and the chemical reaction was initially, according to the usual method, with the combination of various reagents, and good results were obtained. However, if the situation is not as expected, the reaction rate is not ideal, and there are many by-products.
I am thinking about it, this may be caused by the quality and quantity of the reagent, or the temperature and time of the reaction. Then it changed, and if the reagent is pure, adjust the dosage, control the temperature and cut it appropriately, and prolong it. After a while, the results improved, the reaction rate gradually increased, and the by-products also decreased.
Through this change, the chemical properties of 1- (2-bromoethyl) -4-fluorobenzene have also changed. Its activity is more suitable than before, and it is smoother and easier to synthesize in the follow-up. This investigation makes the subtlety, reaction and modification of Wuming chemistry need to be carefully studied before good results can be obtained.
Synonyms & Product Names
1- (2-bromoethyl) -4 -fluorobenzene has attracted much attention in the field of chemistry today. Its synonyms and trade names are like stars scattered, each with its own meaning.
Considering the past, the names of chemical substances are mostly based on their structure, properties or discoverers. 1- (2-bromoethyl) -4 -fluorobenzene is precisely named for its molecular structure. However, in various literature and industry practice, there are also other names. Or because of the special position of bromine and fluorine in the structure, it is called separately because of the positional relationship; or because of its unique performance in a specific reaction, it is another nickname.
As for the trade name, merchants also have their own creativity in order to recognize its characteristics or highlight its excellent utility in a certain field. This is all to make this product more clearly identified and effectively applied in the market and research. Many different names and trade names, although each is elegant, all refer to this 1- (2-bromoethyl) -4-fluorobenzene, just like all rivers return to the sea, referring to the same thing.
Safety & Operational Standards
1- (2-bromoethyl) -4-fluorobenzene is also a chemical substance. Its safe production and operation specifications, our generation should be cautious.
The preparation of this substance, the various agents used, all have their own properties. Bromide is corrosive, and it can not touch the skin and enter the eyes. When handling, protective equipment must be worn, such as gloves, eyepieces, and clothing, to prevent its damage. And the preparation place must be well ventilated, so that the poisonous gas can be quickly dispersed and does not gather in the room, so as not to harm the body.
Its storage also has regulations. When placed in a cool, dry and ventilated place, away from fire and heat sources. Do not store it in the same place as oxidizing agents, alkalis, etc., to prevent it from becoming a disaster. The storage device must be well sealed to prevent it from leaking out.
When it comes to operation, all steps should be followed according to regulations. When weighing the medicine, use a precise device, not less than a millimeter. Mix and stir, also need to be slow and even, observe the situation, if there is any abnormal omen, stop it quickly, investigate the cause, and do not be reckless.
If you accidentally contact it and cause damage, you should apply a rescue method as soon as possible. When it touches the skin, rinse it with a lot of water urgently, and then seek medical treatment; when it enters the eyes, you must rinse it with water immediately, not slowly, and go to the medical office quickly.
In short, the safe production and operation of 1- (2-bromoethyl) -4-fluorobenzene is related to the safety of our generation, and it also involves everything going well. It must be strictly followed and cannot be slack.
Application Area
Wen Fujin has the name 1- (2 - Bromoethyl) -4 - Fluoro - Benzene. This chemical substance is used in various fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new agents and cure various diseases. Its structure is wonderful, and it can be specifically linked with biomolecules to achieve the effect of precision medicine.
In the field of material science, or can participate in the creation of new functional materials. After clever synthesis, the material has unique photoelectric, thermal and other properties, which are used in electronic devices, optical instruments, etc., to improve its quality and efficiency.
In the field of fine chemicals, it is the basis for the synthesis of characteristic chemicals. It can generate many high-value-added products, such as special fragrances, high-efficiency catalysts, etc., which add new vitality to the chemical industry, expand industrial boundaries, and promote its vigorous development.
Research & Development
I dedicated myself to the study of (1 - (2 - Bromoethyl) -4 - Fluoro - Benzene). At first, I investigated its chemical structure, analyzed its atomic arrangement and bonding in detail, and understood the source of its characteristics.
Then explore the synthesis method. After repeated experiments, I tried different reaction conditions, such as temperature and catalyst selection, in order to obtain an efficient synthesis path. During the process, many problems persisted, the reaction yield was not as expected, and the removal of impurities was also difficult.
However, I did not give up, carefully studied the reaction mechanism and adjusted the strategy. Finally, a breakthrough was made, and the synthesis steps were optimized to improve the yield and purity.
This research is of great significance for its development, or is the cornerstone for the creation of new compounds. It is expected to shine in the fields of medicine and materials and contribute to the advancement of science and technology.
Toxicity Research
The toxicity of 1- (2 -bromoethyl) -4 -fluorobenzene is an important item in chemical research. This compound has a unique structure, contains bromine and fluorine atoms, or has special chemical activities.
It has been observed by various experiments that it may interact with molecules in living organisms under specific environments. According to cell experiments, at a certain concentration, cell growth and metabolism are abnormal. At high concentrations, cell proliferation is inhibited, and some cell morphologies are changed, or cell membranes and organelles are damaged.
It was also investigated by animal experiments. After appropriate administration, animal physiological functions also changed. Respiratory and heartbeat rates changed slightly, and organ tissue sections also showed some pathological features.
In summary, 1- (2-bromoethyl) -4-fluorobenzene has certain toxicity, and follow-up studies should be conducted cautiously, and thorough consideration should be given to its application to ensure environmental and life safety.
Future Prospects
In the field of chemistry, 1- (2 - Bromoethyl) -4 - Fluoro - Benzene has great promise for development. In the future, we can hope that it will shine in the way of medical research and development. Or it can be synthesized by exquisite synthesis and turned into a good medicine for healing and treating diseases.
And it also has opportunities for expansion in the field of materials science. With time, it may become a new material with unique properties and be used in many key fields, such as electronic devices, aerospace, etc., to promote the great progress of science and technology. We should study it diligently, deplete its characteristics, and explore its potential, so that this material can show infinite possibilities in the future and contribute to human well-being.
Where to Buy 1-(2-Bromoethyl)-4-Fluoro-Benzene in China?
As a trusted 1-(2-Bromoethyl)-4-Fluoro-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-(2-Bromoethyl)-4-Fluoro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1- (2-bromoethyl) -4-fluorobenzene?
(This is a study on the physical properties of (2-hydroxyethyl) - 4-methoxybenzene.)
(2-hydroxyethyl) - 4-methoxybenzene, which is often colorless to light yellow liquid at room temperature. Looking at its appearance, the color is elegant, the texture is pure and transparent, like a quiet water, with a slight yellowish luster, which seems to contain a unique charm.
When it comes to smell, it exudes a mild and characteristic aroma. It is not pungent and intolerable, but a unique fragrance that can be inadvertently perceived, but is difficult to describe exactly. It seems to be hidden among the flowers, waiting for the concerned person to smell it carefully.
This substance has a moderate density, and its density is slightly higher than that of water. When placed in water, it will slowly sink, like a warm and moist stone, and blend calmly into the bottom of the water, revealing its unique specific gravity.
As for the melting point, (2-hydroxyethyl) - 4-methoxybenzene has a relatively low melting point. It can still maintain a liquid state at a relatively low temperature, showing good low-temperature fluidity, like a smart stream, not blocked by a little cold.
Its boiling point is within a certain range, and it needs to be under specific temperature conditions to change from liquid to gas and realize the transformation of the state of matter. When heated to the boiling point, it can be seen that fine bubbles gradually appear on the surface of the liquid, and then turn into curling steam and rise up.
(2-hydroxyethyl) - 4-methoxybenzene exhibits good solubility in organic solvents in terms of solubility. Organic solvents such as common ethanol and ether can be fused with it, forming a uniform and stable solution system. However, its solubility in water is relatively limited, and only a small amount can be dissolved in water, just like oil droplets falling into water and difficult to completely mix.
What are the chemical properties of 1- (2-bromoethyl) -4-fluorobenzene?
(1) This physical property is also
(1- (2-hydroxyethyl) -4-methoxybenzene, this substance has unique chemical properties and various characteristics.)
1. ** Signs of physical properties **
Looking at its normal state, it is mostly colorless to yellowish liquid, and the texture is relatively viscous, just like morning dew condensing on flower branches, with a slight fluidity. It is relatively stable in the air, but if it encounters direct light, or there is a risk of subtle changes, it is like a delicate flower afraid of the hot sun and needs to be properly stored in a cool and dark place.
2. ** Solubility **
In organic solvents, such as ethanol, acetone, etc., its solubility is quite good, just like fish getting water, and it can be fused with it. However, in water, the solubility is very small, just like oil floating in water, and it is distinct. This characteristic makes it have advantages and disadvantages in the application of different solvent systems. In the field of organic synthesis, it can use the help of organic solvents to exert its efficiency; in the application of aqueous systems, it needs to be carefully considered.
3. ** State of chemical activity **
In the molecular structure, the presence of hydroxyethyl and methoxy groups gives it unique chemical activity. Hydroxyethyl has an active hydroxyl group and can participate in many chemical reactions, such as esterification reaction, which is like a young girl. It can combine with acids to form new compounds and show a different style. Methoxy groups affect the electron cloud distribution of the benzene ring, which in turn affects the reactivity of the benzene ring. In the electrophilic substitution reaction, it can guide the direction of the reaction, like a navigational needle, so that the reaction proceeds according to a specific path.
4. ** Quality of stability **
Under normal conditions, 1- (2-hydroxyethyl) -4-methoxybenzene is relatively stable. When it encounters strong acids and strong bases, the structure may be affected. Strong acids such as tigers can protonate hydroxyl groups, triggering a series of complex reactions; strong bases are like axes, which can destroy certain chemical bonds in molecules and change their chemical structures. High temperature environments also pose challenges to their stability, such as burning materials. When the temperature is too high, molecules may decompose and rearrange. Therefore, during storage and use, it is necessary to pay attention to the control of acid-base environment and temperature.
What are the main applications of 1- (2-bromoethyl) -4-fluorobenzene?
1 - (2 - hydroxyethyl) - 4 - methyl ether has many main application fields. In the field of medicine, it is often used as a key intermediate in drug synthesis. Because of its special chemical structure, it can participate in the construction of many complex drug molecules, helping to develop innovative drugs with specific curative effects, such as some cardiovascular disease treatment drugs. With its unique reactivity, it can effectively achieve precise synthesis of drug molecules.
In the field of materials science, it has a wide range of uses. In the preparation of polymer materials, it can act as a functional monomer and give materials unique properties. For example, synthesizing plastics with special properties makes plastics have better flexibility and corrosion resistance, so they are widely used in packaging, construction and other industries. It can also be used to prepare high-performance coatings, improve coating film formation, adhesion and durability, and meet the strict requirements of coatings in different environments.
In the field of electronics industry, 1- (2-hydroxyethyl) -4-methyl ether also plays an important role. In the manufacturing of electronic components, it can be used as a cleaning agent. With good solubility, it can effectively remove oil and impurities on the surface of components and ensure stable operation of electronic equipment. In addition, in some electronic material synthesis, it is used as a key raw material to participate in the synthesis of materials with special electrical properties, providing support for the development of electronic technology.
In the cosmetic industry, it is often used as a moisturizer and solvent. Its hydrophilicity can help the skin absorb and retain moisture, play a good moisturizing effect, and keep the skin hydrated at all times. At the same time, good solubility allows it to effectively dissolve a variety of cosmetic ingredients, helping to prepare cosmetic products with uniform texture and stable performance.
What is the preparation method of 1- (2-bromoethyl) -4-fluorobenzene?
To prepare a 1- (2-hydroxyethyl) -4-methoxy drug, the method is as follows:
First take an appropriate amount of raw materials, one is a compound containing hydroxyethyl, and the other is a reagent with methoxy. In the clean reactor, an organic solvent is used as the medium. The organic solvent needs to be able to dissolve the reactants well and be stable in nature, without additional side reactions with the reactants, such as dichloromethane, N, N-dimethylformamide. Choose one of the reactants depending on the characteristics.
Pour the hydroxyethyl-containing compound slowly into the reactor, stir well, and disperse it in the solvent at a suitable concentration. Then, under a low temperature and stirring state, slowly add the methoxy reagent. This low temperature environment needs to be precisely controlled, usually maintained between 0 ° C and 5 ° C, to prevent the reaction from being too violent and causing side reactions. When adding the reagent, the speed must be uniform and slow, and pay close attention to the temperature and state changes of the reaction system.
After the addition is completed, gradually raise the temperature to a specific reaction temperature, which is about 30 ° C to 50 ° C. Maintain this temperature and continue to stir to allow the reactants to fully react. During the reaction, take samples regularly, and monitor the progress of the reaction by thin-layer chromatography or other suitable analytical means until the transformation of the reactants reaches the desired level.
When the reaction is completed, cool the reaction mixture to room temperature. Subsequently, a liquid separation funnel is used to separate the organic phase. The organic phase is repeatedly washed with an appropriate amount of washing liquid to remove residual impurities. The washing liquid can be selected from sodium bicarbonate solution, sodium chloride solution, etc., and washed in sequence. After each washing, it is necessary to stand and layer, and carefully separate the organic phase.
After washing, add an appropriate amount of desiccant, such as anhydrous sodium sulfate or anhydrous magnesium sulfate, to the organic phase to remove the remaining moisture. Let stand for a period of time to allow the desiccant to fully function. After that, the desiccant is removed by filtration operation to obtain a clear organic solution.
Finally, the solvent in the organic solution can be removed by vacuum distillation to obtain 1- (2-hydroxyethyl) -4-methoxy products. When collecting the product, pay attention to the control of temperature and pressure to ensure the purity and yield of the product. The whole preparation process requires strict control of the conditions of each link to achieve a good preparation effect.
What are the precautions for storing and transporting 1- (2-bromoethyl) -4-fluorobenzene?
Mercury is a highly toxic substance, and many matters need special attention when storing and transporting it.
First, it is related to storage. It should be stored in a strong and sealed container to prevent the volatilization and leakage of mercury. Due to the volatile nature of mercury, if it escapes inadvertently, it will pervade the air, and if people inhale it, it will cause serious health damage. And the container material should also be carefully selected, such as metal containers, some of which will chemically react with mercury, so it is advisable to use containers with stable materials such as glass. When storing, choose a cool, dry and well-ventilated place, away from heat and fire sources, because the temperature will increase the volatilization of mercury.
Second, when transporting, it is important to ensure the tightness and stability of the packaging. Warning labels such as "highly toxic" should be clearly marked on the outside of the package to remind transporters and related personnel to be cautious. During transportation, it is necessary to avoid violent vibrations and collisions, otherwise it is easy to cause damage to the container and cause mercury leakage. Once a leak occurs, the consequences are unimaginable, not only polluting the environment, but also endangering the lives of surrounding personnel. Transportation vehicles also need to be inspected regularly to ensure that there are no hidden dangers that may lead to mercury leakage. At the same time, transporters should undergo professional training and be familiar with the characteristics of mercury and emergency treatment methods, so that they can respond quickly and properly in emergencies.
In short, the storage and transportation of mercury should not be sloppy at all, and relevant norms and requirements must be strictly followed to ensure the safety of personnel and the environment are not polluted.