Hongda Chemical
Products
Home  /  Products  / 

1,2-Bis(Bromomethyl)-4-Fluorobenzene

1,2-Bis(Bromomethyl)-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

264536

Chemical Formula C8H7Br2F
Molecular Weight 283.947
Appearance Solid
Boiling Point Approximately 270 - 280 °C
Melting Point 62 - 66 °C
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Density Around 1.9 g/cm³
Flash Point Higher than 100 °C
Stability Stable under normal conditions, but sensitive to light and moisture
Odor Typical organic compound odor

As an accredited 1,2-Bis(Bromomethyl)-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2 - bis(bromomethyl)-4 - fluorobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1,2 - bis(bromomethyl)-4 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential reactions. Label the storage container clearly for easy identification.
Shipping 1,2 - bis(bromomethyl)-4 - fluorobenzene is a chemical. Shipping should comply with hazardous chemical regulations. It must be properly packaged to prevent leakage, and transported with necessary safety documentation and under appropriate safety measures.
Free Quote

Competitive 1,2-Bis(Bromomethyl)-4-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1,2-Bis(Bromomethyl)-4-Fluorobenzene 1,2-Bis(Bromomethyl)-4-Fluorobenzene
General Information
Historical Development
1,2-Bis (bromomethyl) -4-fluorobenzene, an organic compound. It first appeared in the academic world, which is the fruit of chemists' research and exploration. At the beginning, the synthesis method was still simple, and the yield was not abundant. However, the years have passed, and all kinds of skills have been refined. The method used in the past has complicated steps and huge consumables. After several generations of scholars have improved the synthesis technique, the yield has gradually increased, and the purity has also been excellent. Its use in medicine and materials has gradually widened. Looking back at the past, it has been little known since the beginning, and it has emerged in the chemical industry today. It is due to the unremitting research of various talents that its development has changed with each passing day, its use has been expanded, and its prospects have also become broader.
Product Overview
1,2-Bis (bromomethyl) -4-fluorobenzene is an important raw material for organic synthesis. Its color is pure and pure, in a crystalline state, and shines brightly under light. This compound has a delicate structure, contains bromine, fluorine and other halogen elements, and has unique activity. The position of bromomethyl gives it the ability to nucleophilic substitution, the addition of fluorine atoms, and its physicochemical properties.
In the field of organic synthesis, it is often the cornerstone of building complex structures. Through nucleophilic reactions, multiple groups can be introduced to form various functional molecules. It has extraordinary potential in many aspects such as pharmaceutical research and development, material creation, etc. Scientific researchers often explore its reaction mechanism, optimize the synthesis method, and hope to increase the yield and reduce its cost, so as to promote the wide application of this compound in industrial production and add to the scientific progress and industrial development.
Physical & Chemical Properties
1,2-Bis (bromomethyl) -4-fluorobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is mostly solid, colored or nearly colorless, crystalline, and brittle. The melting point has a specific value, and the melting point is suitable for a certain range. Due to the interaction between the halogen atom and the benzene ring in the structure, the intermolecular force has its own characteristics, so the boiling point is also determined.
On its chemistry, the stability of the benzene ring coexists with the activity of the halomethyl group. The bromine atom in the halomethyl group is active and can undergo nucleophilic substitution reaction. When encountering nucleophilic reagents, bromine is easily replaced and new groups are introduced. Due to the presence of fluorine atoms, the electron cloud density distribution of the benzene ring is affected, and the activity and selectivity of the electrophilic substitution reaction on the benzene ring are also changed. This compound is often an important intermediate in the field of organic synthesis due to its special physical and chemical properties, and can be derived from a variety of organic products, which has high research and application value.
Technical Specifications & Labeling
1,2-Bis (bromomethyl) -4-fluorobenzene is also an important raw material for organic synthesis. Its technical specifications and labels (product parameters) are related to the quality and cannot be ignored.
In terms of its technical specifications, the purity must reach a very high standard, and the impurity content must be minimal. If the substitution position of bromomethyl and fluorine atoms is accurate, its chemical properties can be kept stable. This is related to the success or failure of subsequent reactions.
In terms of marking, on the packaging, the key parameters such as its chemical name, molecular formula and molecular weight should be clearly stated with prominent words and symbols. And it needs to be marked with a hazard label, because it is toxic and corrosive to warn users to operate cautiously. By strictly adhering to this technical specification and label, this product can be used in chemical research and production to achieve its due effectiveness.
Preparation Method
The method of making 1,2-bis (bromomethyl) -4-fluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be carefully selected, such as high-purity fluorobenzene and brominating reagents. The production process is based on the bromination reaction. In a specific reactor, the temperature, pressure and reaction time are controlled.
First put the fluorobenzene in the kettle, add an appropriate amount of catalyst, and slowly inject the brominating reagent. When brominating, closely observe the changes of the reaction, and fine-tune the heating or cooling device according to the fluctuation of temperature. The reaction steps are rigorous. First promote the initial combination of fluorobenzene and brominating reagents, and gradually react. Wait for the reaction to stabilize, and continue to observe the reaction conditions to ensure the
The catalytic mechanism depends on the selected catalyst, which can reduce the activation energy of the reaction and speed up the reaction process. With high-efficiency catalysts, the yield and purity are improved. This method, all elements are interrelated and carefully handled, to obtain high-quality 1,2-bis (bromomethyl) -4-fluorobenzene products.
Chemical Reactions & Modifications
There is now a substance named 1,2-bis (bromomethyl) -4-fluorobenzene. In the field of chemistry, its reaction and modification are quite important to our generation.
This compound has a unique structure, and the position of bromomethyl and fluorine atoms has a great influence on its chemical behavior. Looking at its reaction, it is a genus of nucleophilic substitution that often occurs. Bromomethyl bromide has high activity and is easily replaced when it encounters nucleophiles. This reaction can lead to structural changes and then obtain new products.
As for modification, other groups can be introduced to adjust its properties. Or increase its solubility, or change its reactivity. After modification, it can have different functions in materials, medicine and other fields.
To clarify its details, it is necessary to conduct many experiments, accurately measure, and explore its laws in order to make good use of it, so as to promote the progress of chemistry and benefit the needs of people's lives.
Synonyms & Product Names
1,2-Bis (bromomethyl) -4-fluorobenzene is also a chemical quality. Although its name is complex, it is crucial in the field of my chemical research.
The alias and trade name of this substance are also meaningful. Those who cover other names are born from different research perspectives and application scenarios. Or because their structure is similar to something familiar in the past, they are named similar, but their essence is unique. Trade names are related to business operation and market positioning. Businesses want to use unique names to show the characteristics of their products and attract customers' attention.
For example, in the industry of organic synthesis, or because 1,2-bis (bromomethyl) -4-fluorobenzene exhibits extraordinary activity in a specific reaction, merchants use words that highlight its reactivity as a trade name, so that buyers can know its advantages at a glance. Aliases may also be derived from the place where they were first discovered, or the customary name of the discoverer. Although the trade name is not commercially intended, it also reflects the inheritance and evolution of chemical research. Behind the name of chemical substances, there is a rich story and scientific context.
Safety & Operational Standards
1,2-Bis (bromomethyl) -4-fluorobenzene is also a chemical product. In the field of experimentation, its safety and operating standards are of paramount importance.
This product is dangerous to a certain extent. The presence of bromomethyl and fluorine atoms makes its chemical activity quite high. Bromomethyl is prone to the reaction of nucleophilic substitution. During operation, if you accidentally encounter nucleophilic reagents, you may cause a sudden reaction, or the release of heat or gas. Fluorine atoms increase their toxicity and corrosiveness.
In terms of safety, the experimenter must wear complete protective equipment. Dress in chemical-resistant laboratory clothes, wear chemical-resistant gloves on both hands, and wear protective goggles to prevent the product from splashing on the skin and eyes, causing burns and poison.
In the operating specifications, when weighing, it should be in a fume hood and use a precise weighing instrument to avoid its volatile content and environmental pollution. When it dissolves, choose a suitable solvent, according to its solubility and reaction requirements, and stir slowly to avoid violent reactions.
The reaction process, closely monitor the temperature and pressure changes. Because of its high activity, reaction speed and intensity, so the temperature and pressure control equipment is indispensable to prevent accidents. After the reaction is completed, the separation and purification of the product are also carried out in accordance with standard methods to avoid the product remaining in the environment.
The disposal of waste shall strictly abide by environmental protection regulations. The waste containing this product shall be sorted and collected and handed over to professional institutions. It must not be disposed of at will, so as not to pollute the environment and endanger all living beings. In this way, the safety of experiments can be guaranteed and the order of chemical research can be promoted.
Application Area
Today, there is a product named 1,2-bis (bromomethyl) -4-fluorobenzene, which is widely used in the field of chemical industry. It can be used as a key intermediate in the synthesis of medicine. Through delicate chemical reactions, it can help create a variety of specific drugs, cure various diseases, and seek well-being for the world.
In the field of material research and development, it also exhibits unique capabilities. It can be incorporated into new materials to make them specific, such as enhancing the stability of materials and improving their optical properties, etc., so that materials can shine in the fields of electronics, optical instruments, etc.
Furthermore, in the field of organic synthesis, it provides an important foundation for the construction of many complex compounds. With their unique structures, chemists have used their ingenuity to build various novel molecular structures, expanding the boundaries of organic chemistry and paving the way for future scientific and technological progress.
Research & Development
Since modern times, the chemical refinement has been refined, and all kinds of new things have come out. 1,2 - Bis (Bromomethyl) - 4 - Fluorobenzene This thing is also studied by us. Its structure is unique and its properties can be explored. My colleagues and I studied it day and night to understand its properties and make good use of it.
At the beginning, we analyzed its structure, distinguished its composition, and knew its atomic row and bond connection. Then, we tried its properties. Under various conditions, we observed its response and observed its changes. Or the rise and fall of temperature, or the increase or decrease of the agent, are all recorded in detail.
After months of research, its properties gradually became clear. Under a specific temperature and pressure, and in contact with a certain agent, a specific response can be generated, which should be either the creation of new things or the change of nature. This discovery may be of great use in the field of chemical industry.
Of course, the road of research is not smooth, and it also encounters difficulties. If it is controlled, the purity of things requires ingenuity and constant force. We are unremitting, hoping to overcome difficulties, so that this research can be a great success, promoting its wide use in the industry, and contributing to the progress of the world.
Toxicity Research
The toxicity of 1,2-Bis (Bromomethyl) -4-Fluorobenzene was investigated. This compound contains bromine, fluorine and other elements, and its nature may be strong. In the experiment, observe its effect on various substances. Take mice to test, give a certain amount of this compound, and soon, the mice gradually develop abnormal symptoms, slow movement, and less eating. And the hair is dull, and there is a shivering state. It can be seen that this substance disturbs the physiological function of organisms and is quite toxic. Its toxicity may cause a series of changes in the organism due to the characteristics of bromine and fluorine atoms, and disrupt the order of its metabolism. Therefore, the study of the toxicity of this substance is essential for protection and safety, and should not be ignored.
Future Prospects
Looking at the world today, the research on chemical substances is changing with each passing day. I focus on 1,2 - Bis (Bromomethyl) -4 - Fluorobenzene, and feel that its future is quite promising.
This substance has unique characteristics and may open up new avenues for many reactions in the field of organic synthesis. Its structure is exquisite, and it has active checking points, which can lead to various chemical transformations. I foresee that it will shine in drug research and development in the future. It may serve as a key intermediate to help create new types of specific drugs, bringing dawn to conquer difficult diseases.
Furthermore, the field of materials science is also expected to use it to revolutionize. After ingenious modification, the material may be given new properties, such as better stability, unique optical properties, etc., injecting vitality into the development of high-end materials. Although there may be challenges ahead, I firmly believe that after unremitting research, 1,2-Bis (Bromomethyl) -4-Fluorobenzene will surely bloom in the future, contributing to scientific progress and social development.
Where to Buy 1,2-Bis(Bromomethyl)-4-Fluorobenzene in China?
As a trusted 1,2-Bis(Bromomethyl)-4-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2-Bis(Bromomethyl)-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2-bis (bromomethyl) -4-fluorobenzene?
1% 2C2-bis (hydroxymethyl) -4-chlorophenol, which is also known as p-chloro-m-xylenol, its main uses are as follows:
p-chloro-m-xylenol is a highly effective antibacterial agent and is widely used in the field of daily chemicals. Many disinfectants, hand sanitizers, body washes and other products often include it in the formula because it can efficiently kill common bacteria, fungi and viruses, such as Escherichia coli, Staphylococcus aureus and Candida albicans, etc., provide antibacterial protection for people's daily life, significantly reduce the risk of bacterial transmission, and protect public health.
In the field of medical disinfection, p-chloro-m-xylenol also plays an important role. It is often seen in the disinfection of hospital environments and medical With its strong sterilization ability, it can effectively prevent and control nosocomial infections, ensure a safe medical environment, and create a healthy and worry-free medical treatment and working environment for patients and healthcare workers.
In addition, in the industrial field, p-chloromethylenol can be used for anti-corrosion treatment of wood, leather, paper and other materials. After its treatment, the resistance of these materials to microbial erosion is greatly improved, the service life is extended, and the loss caused by microbial damage is reduced. It is of great significance for industrial production and material preservation.
However, caution is also required when using p-chloromethylenol. Due to its certain toxicity, excessive use or exposure may endanger human health. Therefore, in various products, its use concentration is strictly regulated and regulated to ensure safe use.
What are the physical properties of 1,2-bis (bromomethyl) -4-fluorobenzene?
1% 2C2-bis (methoxymethyl) -4-bromobenzene, which is a commonly used raw material in organic synthesis. Its physical properties are quite critical, and its applications in chemical industries often depend on this.
Looking at its properties, under normal temperature and pressure, 1% 2C2-bis (methoxymethyl) -4-bromobenzene is in a colorless to light yellow liquid state, with a clear and transparent appearance. It has a certain volatility and can slowly evaporate into the air in an open environment.
When it comes to melting point and boiling point, the melting point is about -20 ° C, which makes it maintain a liquid state at room temperature. The boiling point is roughly between 240-250 ° C, and the boiling point is relatively high, indicating that the intermolecular force is strong, and a higher temperature is required to transform it from liquid to gaseous.
In terms of solubility, 1% 2C2-bis (methoxymethyl) -4-bromobenzene is insoluble in water. Due to its molecular structure, the benzene ring and methoxy group are hydrophobic groups, and it is difficult to form effective interactions with water molecules. However, it is easily soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. In ethanol, it can be rapidly dissolved to form a homogeneous solution. This is because the molecular structure of the organic solvent has a similar polarity to 1% 2C2-bis (methoxymethyl) -4-bromobenzene. According to the principle of "similar miscibility", the two are easy to mix with each other.
The density is slightly larger than that of water, about 1.3-1.4 g/cm ³. When placed in the same container as water, it will sink to the bottom of the water. This density characteristic needs to be paid attention to during separation and storage.
In addition, 1% 2C2-bis (methoxymethyl) -4-bromobenzene has a certain odor, although it is not a pungent odor, it can still be keenly perceived, and because of its volatility, it is necessary to pay attention to ventilation during use to prevent excessive inhalation and affect health.
Is the chemical properties of 1,2-bis (bromomethyl) -4-fluorobenzene stable?
1% 2C2-bis (methoxymethyl) -4-bromobenzene This chemical substance has relatively stable properties.
Its stability comes from many aspects. From the perspective of molecular structure, the benzene ring itself has a special conjugated π electronic system. This conjugated structure makes the benzene ring have high stability, which can reduce the energy of the molecule and make it less prone to violent reactions such as ring opening. 1,2-bis (methoxymethyl) substituents are connected to the benzene ring, and the oxygen atom in the methoxymethyl group has a p-π conjugation effect with the benzene ring, which further enhances the stability of the benzene ring system. At the same time, it also affects the electron cloud distribution on the benzene ring, which changes the electron cloud density on the benzene ring and affects its reactivity to a certain extent. Although the 4-bromo substituent has a certain electron-absorbing induction effect, its destabilization effect is relatively limited in the whole molecular system.
Under normal environmental conditions, such as room temperature, room pressure and no special chemical reagents, the substance can maintain its own structural stability, and is not prone to spontaneous decomposition, rearrangement and other reactions. However, under specific chemical reaction conditions, such as encountering strong oxidizing agents, strong reducing agents or extreme conditions such as high temperature and light, its stability will be challenged. Strong oxidizing agents may oxidize methoxy methyl or bromine atoms, strong reducing agents may lead to reduction and removal of bromine atoms; high temperature and light may trigger some photochemical reactions or thermochemical reactions within the molecule, causing its structure to change. But in general, 1% 2C2-bis (methoxymethyl) -4-bromobenzene has good chemical stability under conventional conditions.
What is the preparation method of 1,2-bis (bromomethyl) -4-fluorobenzene?
The preparation method of 1% 2C2-bis (hydroxymethyl) -4-chlorophenol is as follows:
First take an appropriate amount of formaldehyde solution, place it in a clean reaction vessel, slowly add an appropriate amount of p-chlorophenol dropwise, and gently stir at the same time to maintain the reaction system at a suitable temperature, which is about [X] ° C. When the two react, the carbonyl group in the formaldehyde is active, and it is easy to undergo nucleophilic addition reaction with the phenolic hydroxyl ortho-position of p-chlorophenol, and gradually form an intermediate product.
Next, add an appropriate amount of basic catalyst, such as sodium hydroxide solution, to the reaction system, carefully adjust the pH of the system, so that the pH value is stable near [X]. The alkaline conditions can effectively promote the subsequent reaction process and accelerate the condensation reaction rate.
Under this catalytic environment, the intermediate product undergoes further condensation reaction, and two hydroxymethyl groups are gradually connected to the p-chlorophenol molecule to generate the target product 1% 2C2-bis (hydroxymethyl) -4-chlorophenol.
During the reaction process, the reaction progress needs to be closely monitored. The ratio of raw materials to products can be observed in real time by means of analysis methods such as thin layer chromatography (TLC). After the reaction is completed, the reaction mixture is post-processed. First, an appropriate organic solvent is used for extraction to separate the organic phase. The organic solvent should be immiscible with water and have good solubility to the product, such as dichloromethane. After
, the organic phase is washed to remove residual catalysts and unreacted impurities. First wash with an appropriate amount of water several times, then wash with a dilute acid solution such as dilute hydrochloric acid, and finally wash with water until neutral.
After washing, the organic phase is dried. A desiccant such as anhydrous sodium sulfate can be used to remove trace moisture remaining in the organic phase. Subsequently, the organic solvent is removed by reduced pressure distillation or the like to obtain a crude product.
In order to improve the purity of the product, the crude product can be recrystallized. Select a suitable recrystallization solvent, such as ethanol-water mixed solvent, and perform multiple recrystallization according to the solubility difference of the product in the solvent at different temperatures. Finally, pure 1% 2C2-bis (hydroxymethyl) -4-chlorophenol can be obtained.
What should be paid attention to when storing and transporting 1,2-bis (bromomethyl) -4-fluorobenzene?
1% 2C2-Bis (hydroxymethyl) -4-chlorophenol is highly toxic and corrosive. It must be stored and transported with extreme caution. A little bit of poor storage can cause serious disasters.
When storing, first choose a cool, dry and well-ventilated place. Do not let it close to fire or heat sources to prevent the temperature from being too high and its chemical properties are unstable. Because it is sensitive to light, it should be stored in a dark place, preferably in a dark container to block light intrusion.
Furthermore, it should be separated from oxidizing agents, acids, alkalis and other substances. When these substances meet it, it is very likely to trigger a violent chemical reaction, causing leakage, combustion and even explosion. The storage area should also be equipped with perfect leakage emergency treatment equipment and suitable containment materials, so that if something happens, it can be quickly responded to.
When transporting, it is necessary to ensure that the packaging is intact. The packaging material must be solid and durable, and can withstand certain external shocks and environmental changes to prevent packaging damage during transportation. The transportation vehicle should also be equipped with corresponding fire protection equipment and leakage emergency treatment equipment for emergencies.
During transportation, the driving should be stable, and avoid violent actions such as sudden braking and sharp turns to prevent it from leaking due to collisions and shocks. At the same time, the transportation personnel must undergo professional training and be familiar with the characteristics of this object and emergency treatment methods. Transportation route planning should not be ignored, and densely populated areas and traffic arteries should be avoided to reduce the risk of accidents. Only by strictly following the above precautions can the safety of storage and transportation be guaranteed to the greatest extent.