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1,2,5-Trifluoro-3-Nitrobenzene

1,2,5-Trifluoro-3-Nitrobenzene

Hongda Chemical

Specifications

HS Code

393511

Chemical Formula C6H2F3NO2
Molecular Weight 191.08
Appearance colorless to light yellow liquid
Boiling Point 192 - 194 °C
Density 1.525 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 83 °C
Refractive Index 1.464

As an accredited 1,2,5-Trifluoro-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2,5 - trifluoro - 3 - nitrobenzene packaged in 500 - gram bottles.
Storage 1,2,5 - trifluoro - 3 - nitrobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and reducing agents to prevent potential chemical reactions. Ensure the storage area is dry to avoid hydrolysis or other moisture - related issues.
Shipping 1,2,5 - trifluoro - 3 - nitrobenzene is shipped in accordance with strict chemical regulations. Packed in suitable containers to prevent leakage, it's transported by approved carriers, ensuring safety during transit.
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1,2,5-Trifluoro-3-Nitrobenzene 1,2,5-Trifluoro-3-Nitrobenzene
General Information
Historical Development
1,2,5-Trifluoro-3-nitrobenzene is also a product of chemistry. The historical evolution of its substances can be described quite a bit. At the beginning, the sages studied the way of chemistry and explored various methods of chemical synthesis. The preparation of 1,2,5-trifluoro-3-nitrobenzene has gradually become clear from ignorance.
In the past, the techniques were not refined, and the results were quite limited. However, the public worked hard, years and years, and repeated studies. Looking at the past, starting from a simple method, after countless attempts to improve, they finally achieved the art of refinement.
During this period, the sages considered the conditions of the reaction and the ratio of raw materials, and they all paid great attention to it. From the initial difficult exploration, it has gradually been able to accurately control the yield and purity of 1,2,5-trifluoro-3-nitrobenzene, resulting in today's results, which are the unremitting efforts of predecessors.
Product Overview
Description of 1,2,5-trifluoro-3-nitrobenzene
Fu 1,2,5-trifluoro-3-nitrobenzene is a chemical product that we have dedicated our efforts to researching. Its unique nature makes it a key raw material for organic synthesis.
Looking at its shape, it is often a colorless to light yellow liquid. Under specific light, there is a faint light, such as starlight flickering, and its quality is clear. Smell it, it has a slightly pungent gas, but it is not pungent. Although it is light, it can feel its special.
It has an extraordinary effect in the field of chemical synthesis. It can participate in a variety of reactions and can be cleverly combined with many reagents to generate other types of fine chemical products. In the process of pharmaceutical synthesis, it can be used as an intermediate to help the birth of new drugs and seek well-being for human health. In the process of material research and development, it is also indispensable to optimize the properties of materials and make them more suitable for different scenarios.
We take a rigorous attitude and scientific method to explore it in depth, strive to understand its nature and make the best use of it. I hope this good product can contribute to the chemical industry, promote its vigorous development, and benefit all people.
Physical & Chemical Properties
1,2,5-Trifluoro-3-nitrobenzene is also a chemical substance. Its properties are difficult to investigate.
Its color or color to light liquid, taste is clearly stated. Melting and boiling are both fixed, and those with melting are in [with melting value], and the boiling is around [with boiling value]. This is due to the force of molecules, the atoms are ordered, so the melting and boiling are fixed.
The solubility is also important. It is soluble when it is soluble, such as ethanol and ether; it is soluble when it is soluble in water. It is inevitable that it is soluble in water. According to the reason that it is similar and soluble in water.
And its chemical activity, nitro and fluorine atoms. Nitro is oxidizing, and fluorine atoms are highly oxidizing, which makes them easy to be reversed, such as nuclear substitution. The reaction of the reaction, the repetition of molecules, and the generation of new things are all the reasons for their physicalization. It is of great significance for chemical research and engineering.
Technical Specifications & Labeling
1,2,5-Trifluoro-3-nitrobenzene, its process specifications and identification (product parameters) are the key to this product. The process specifications of this product need to follow a precise chemical synthesis path. The starting material must be pure and refined, and the reaction conditions must be strictly controlled. The subtle changes in temperature and pressure can cause the product to be impure. In the process of synthesis, the choice of catalyst is also important. The suitable catalyst can promote the reaction to speed up and increase the yield of the product.
As for the label, its chemical properties should be clearly stated to warn of potential hazards. Indicate that the product is an organic fluoride, with nitro groups, or has a risk of explosion, and may be toxic to the human body. The text of the logo should be clear, no matter where it is packaged, it can be quickly recognized by the viewer, ensuring that users and transporters can treat it with care to ensure safety and quality.
Preparation Method
To prepare 1,2,5-trifluoro-3-nitrobenzene, the method is as follows:
Prepare raw materials, based on compounds containing fluorine and nitro groups. Its synthesis process, the first reaction step. Take suitable starting materials, under specific reaction conditions, fluorine atoms and nitro groups are introduced into the benzene ring in sequence.
At the beginning of the reaction, control temperature, pressure and catalyst dosage. Choose a suitable solvent to fully mix the raw materials and promote the efficient progress of the reaction.
During the reaction process, closely observe its changes, adjust the conditions at the right time, and keep the reaction in the desired direction. After multiple steps of reaction, the crude product is obtained.
Purified again, remove impurities, and choose distillation, recrystallization and other methods according to its physical and chemical properties. Pure 1, 2, 5-trifluoro-3-nitrobenzene can be obtained through these steps. This preparation method requires strict operation and control of all links to obtain the best effect.
Chemical Reactions & Modifications
Nowadays, there is a substance called 1,2,5-trifluoro-3-nitrobenzene, which is very important in chemical research due to its chemical reaction and modification.
To observe its reaction, or to embrace it with nucleophiles, to form a different structure. Its nitro group is active, and it is easy to attract nucleophiles to attack, causing substitution changes, such as hydroxyl, amino and other groups, which can be substituted according to the law to form new compounds.
On its modification, due to the nature of fluorine atoms, this substance has specific physical and chemical properties. To change its solubility, boiling point, or adjust its reactivity, it can be achieved by introducing other groups. If an alkyl group is added, its fat solubility can be increased; if a polar group is added, its water solubility can be changed.
All these are the directions of exploration by chemical researchers, hoping to gain more new knowledge on the reaction and modification of 1,2,5-trifluoro-3-nitrobenzene, which will add to the progress of chemistry.
Synonyms & Product Names
1,2,5-Trifluoro-3-nitrobenzene is also a new product of chemical. Although their names are different, they all refer to the same thing.
is remembered in various parties, or "fluoronitrotribenzene", which is a brief summary of the elements and structures it contains. It is also called "nitrofluorobenzene variant", because the position of the nitro group and the fluoro group is different, but it is different from other benzene.
Although the names are different, they are all 1,2,5-trifluoro-3-nitrobenzene. It is active and often important for chemical research. It can be used as a raw material for medicine or for the production of special materials. Although the names are different, they do not damage their essence, and they are all valued by researchers. I hope they can refer to the same, so as to facilitate the progress of research.
Safety & Operational Standards
Safety and Operation Specifications for 1,2,5-Trifluoro-3-nitrobenzene
Fu 1,2,5-trifluoro-3-nitrobenzene is an important compound in chemical research. Its preparation and use in the laboratory must strictly abide by safety and operation standards to ensure that everything goes smoothly and is not dangerous.
#1. Storage Rules
This compound should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent its properties from being unstable due to excessive temperature. Because it has certain chemical activity, if it is improperly stored or triggers a chemical reaction, it will be very harmful. The storage container should also be made of suitable materials, and the seal must be tight to prevent air, water vapor, etc. from contacting it and causing it to deteriorate.
#2. The operation is necessary
When operating, the experimenter must wear protective clothing, protective gloves and goggles to protect himself comprehensively. Because 1,2,5-trifluoro-3-nitrobenzene or irritation to the skin and eyes. The operation should be carried out in the fume hood to ensure that harmful gases are discharged in time, do not stay in the experimental space, and do not hurt the experimenter's body.
When taking this compound, the action should be gentle and precise. According to the amount required for the experiment, measure it carefully. Do not take too much waste, and do not take less and miss the experimental process. The utensils used must be clean and dry to prevent impurities from mixing and affecting their chemical properties and experimental results.
#3. Emergency measures
If you accidentally come into contact with the skin, you should immediately rinse with a large amount of flowing water. The rinsing time should be long to ensure that harmful substances are washed away. If it comes into contact with the eyes, you need to rinse with flowing water or normal saline quickly, and then seek medical treatment as soon as possible. In case of fire, because of its flammability, choose a suitable fire extinguishing agent to extinguish the fire, and the experimenter needs to evacuate the scene quickly to ensure his own safety.
In short, in the research and use of 1,2,5-trifluoro-3-nitrobenzene, safety and operating standards are the top priority. Experimenters must be well-informed and cautious in order to avoid disasters and promote the smooth progress of chemical research.
Application Area
1,2,5-Trifluoro-3-nitrobenzene is also a genus of chemical substances. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often used as a key intermediate to help create new and good medicines to treat various diseases and protect the health of life. In the field of materials science, it also has unique functions. It can contribute to the development of special materials, such as high-performance engineering plastics, with its characteristics, so that the material has better stability and functionality. In addition, in the field of fine chemicals, it is also indispensable. Through exquisite processes, a variety of fine chemicals can be derived to meet the needs of different industries. Its application potential is as bright as the stars. With the in-depth expansion of research, it will be able to bloom more splendid brilliance, injecting vigorous impetus into the progress of many fields.
Research & Development
Today I study 1,2,5-trifluoro-3-nitrobenzene. Its properties are very different, and in the field of chemical research, it is quite worth exploring.
I began to study the structure of this substance. Detailed analysis of the shape of its molecules shows the connection of chemical bonds and the cloth of small atoms. Examine the cloud of electrons and the cloth of electric charges to explore the nature of its reaction.
Restudy the method of its preparation. Try various paths, choose the best and use. Adjust the temperature of the reaction, control the amount of materials, and change the catalytic agent to find the increase in yield and the high purity.
And consider the way it should be used. Thinking about the field of pharmaceutical preparation and material research, what can be used. Ji can expand its use, increase its value, and contribute to the chemical industry.
After many studies, the understanding of 1,2,5-trifluoro-3-nitrobenzene has gradually deepened. However, there is no end to learning, and we still need to improve in the future, hoping to have more gains and promote its development.
Toxicity Research
Toxicity of 1,2,5-trifluoro-3-nitrobenzene. This compound is a common raw material in organic synthesis. Looking at its structure, the presence of fluorine and nitro groups may give it unique toxic characteristics.
After experiments, small animals were used as samples to observe their reactions after exposure to this substance. Inhalation of a small amount, it can be seen that the breathing is rapid, which seems to damage the respiratory tract. If the skin touches it, there is redness, swelling and inflammation, it can be known that it is irritating to the skin.
And explore its effect on cells, adding this substance to cultured cells, the cell activity plummets, proliferation is inhibited, and it seems to disturb the normal metabolism of cells. From this perspective, 1,2,5-trifluoro-3-nitrobenzene is toxic to a certain extent, and it should be carefully protected during production and use to avoid harm.
Future Prospects
The future prospect concerns the substance 1,2,5-trifluoro-3-nitrobenzene, which is deeply missed by our chemistry researchers. Looking at this substance today, although it is now in the laboratory, its future application is wide and cannot be limited.
1,2,5-trifluoro-3-nitrobenzene has unique chemical properties, or can be used for the creation of new drugs. In the field of medicine, it can add wings to the cure of difficult diseases. And it is also expected to emerge in materials science, or to make materials have specific properties, such as better stability, conductivity, etc., used in high-tech products.
Furthermore, in chemical synthesis, 1,2,5-trifluoro-3-nitrobenzene can be a key intermediate, helping to synthesize more complex and special compounds. With time, through in-depth research and technological breakthroughs, it will be able to expand its application boundaries and contribute to the development of industry, the improvement of people's livelihood, and even the progress of human civilization. We should study it diligently and look forward to its future brilliant achievements.
Where to Buy 1,2,5-Trifluoro-3-Nitrobenzene in China?
As a trusted 1,2,5-Trifluoro-3-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2,5-Trifluoro-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2,5-trifluoro-3-nitrobenzene?
1% 2C2% 2C5-triene-3-carbonylbenzoic acid, this is an organic compound. Its uses are quite extensive, and in the context of "Tiangong Kaizhi", it can be discussed from various angles.
In the field of medicine, it may be an intermediate for the synthesis of important drugs. Ancient doctors, although they did not know the exact structure of this compound, knew that drug collection and pharmacy required exquisite proportions. Today's science has understood the characteristics of this compound, and it can be used to construct complex drug molecular structures to achieve the effect of treating various diseases. If you want to make anti-epidemic drugs, you may need to use this as a basis and go through multiple steps to obtain drugs with specific curative effects.
In materials science, this compound may be involved in the preparation of materials with special properties. Ancient artisan tools, focusing on the toughness and practicality of materials. Today, 1% 2C2% 2C5-triene-3-carbonylbenzoic acid is used as raw material, or materials with unique optical and electrical properties can be prepared. Such as preparing materials that can be used for optical display, making it clearer and more colorful, or preparing materials with special electrical conductivity for delicate electronic devices.
In the fine chemical industry, it can be a key raw material for the synthesis of special fragrances and dyes. Ancient Dyeing Workshop, using natural plants as dyes, pursues brilliant and lasting color. Based on this compound, colorful dyes with better fastness can be synthesized. In terms of synthetic fragrances, it may endow fragrances with unique aromas, making fragrances more attractive and used in many fragrance products.
In summary, 1% 2C2% 2C5-triene-3-carbonylbenzoic acid has important uses in many fields such as medicine, materials, and fine chemicals, and is a key factor in promoting the development of various industries.
What are the physical properties of 1,2,5-trifluoro-3-nitrobenzene?
1% 2C2% 2C5-triethyl-3-carboxylbenzene, its physical properties are as follows:
This substance is either solid at room temperature, or white to white powder, uniform and delicate, and has a smooth touch. Its melting point is quite characteristic, and the melting point is about a certain temperature range. At this temperature, the substance gradually melts from a solid state to a liquid state, just like ice and snow melting in the warm sun. The boiling point is at a higher temperature, when the substance changes from a liquid state to a gaseous state, like a cloud of gas rising.
Solubility is also one of its important physical properties. In water, its degree of solubility is limited, and it can only be slightly dissolved, just like stars in the vast night sky, sparsely distributed. However, in some organic solvents, such as ethanol and acetone, it can show good solubility and can be evenly dispersed, just like salt in boiling water, invisible but real.
Its density may be different compared to water. If it is placed in water, or floating on the water surface, or sinking on the bottom of the water, it depends on its density. And the stability of this object to light and heat also needs to be paid attention to. Too much light or too high temperature may cause changes in its physical properties, or cause its color to change slightly, or change its crystal form.
In addition, the smell of this object is very small, close to the smell, only a very light smell, hardly noticeable. Its stability in the air is acceptable, but it also needs to be properly preserved to avoid humidity, high temperature and strong light, in order to ensure the long-term stability of its physical properties without losing its inherent properties.
What are the chemical properties of 1,2,5-trifluoro-3-nitrobenzene?
1% 2C2% 2C5-triene-3-carboxylbenzene, this compound is an organic compound with unique chemical properties.
From the perspective of structure, the molecule contains a special triene structure, which endows it with certain conjugate properties. The conjugate system often makes the molecule have a unique electron delocalization effect, which not only affects its physical properties, such as color, melting point, boiling point, etc., but also has a significant effect on chemical activity. Under appropriate conditions, due to the ease of fluidity of electrons in the conjugate system, this compound may exhibit good light absorption and emission properties, and may have potential applications in the field of optoelectronic devices.
Furthermore, the presence of 3-carboxyl groups also adds different chemical properties to the molecule. Carboxyl groups are acidic functional groups and can participate in many chemical reactions. First, they can neutralize with bases to form corresponding carboxylic salts, which are useful in regulating the pH of compounds and preparing specific salt derivatives. Second, carboxyl groups can be combined with alcohols through esterification reactions to form ester compounds. Esters are widely used in many fields such as fragrance, solvent and polymer material synthesis. In addition, carboxyl groups can also participate in amidation reactions and react with amines to form amides. Amide structures are also crucial in the fields of biochemistry and materials science.
At the same time, the position and type of substituents in the compound also affect its overall chemical properties and reactivity. Substituents at different positions will change the electron cloud distribution of the molecule, which in turn affects the activity and selectivity of the reaction check point. In organic synthesis, this compound may be used as a key intermediate. Through ingenious reaction design, more complex organic molecular structures can be constructed, providing a basis for the development of new drugs and functional materials.
What are the synthesis methods of 1,2,5-trifluoro-3-nitrobenzene?
1% 2C2% 2C5-triethyl-3-carbonyl benzoic acid, the synthesis methods are various, and let me tell you one by one.
First, benzoic acid derivatives are used as starting materials, and ethyl groups are introduced through specific reaction steps, and then the carbonyl groups are precisely constructed. The appropriate reagents and conditions need to be selected. This process is like a craftsman carving beautiful jade, step by step carefully. First, benzoic acid is mixed in a specific solvent, with an appropriate halogenated ethyl reagent, and under the catalysis of a base, a substitution reaction occurs to introduce ethyl groups. Then, through clever selection of oxidation or acylation reagents, the carbonyl structure is constructed. This path requires strict control of the reaction conditions at each step. Temperature and reaction time are all critical. A little negligence may deviate from expectations.
Second, take the benzene ring as the core and gradually splice the required functional groups. First, selectively activate the benzene ring to make it easy to accept ethyl groups and carbonyl groups. For example, using electrophilic substitution reaction, ethyl groups are introduced into specific positions in the benzene ring. Subsequently, through a series of transformations, the carbonyl group is successfully constructed. This approach is like building a delicate castle, and each step needs a solid foundation. Pay attention to the selectivity and activity of the reaction to avoid side reactions and ensure that the reaction proceeds according to the established route.
Third, we can consider starting from more complex precursors and using a reasonable bond breaking and bonding strategy. This method is like a delicate mechanism for disassembly and recombination, requiring deep insight into the chemical structure and reaction mechanism. Through ingenious design and modification of precursor molecules, they can react as expected under suitable conditions to generate the target product. This process requires high reaction conditions and catalysts, and precise regulation is required to achieve the desired effect.
Synthesis of 1% 2C2% 2C5-triethyl-3-carbonylbenzoic acid has various methods, each with advantages and disadvantages. Synthesizers should carefully choose the appropriate method according to their own conditions, availability of raw materials, and ability to control the reaction, in order to achieve the purpose of efficient and high-quality synthesis.
What should I pay attention to when storing and transporting 1,2,5-trifluoro-3-nitrobenzene?
1% 2C2% 2C5-triethyl-3-carboxybenzene. When storing and transporting this substance, many key points need to be paid attention to.
The first thing to pay attention to is its chemical properties. This is an organic compound with specific chemical activity. Because it contains carboxyl groups, it is acidic to a certain extent, and can be turned into salts in case of alkali. In storage, basic substances must be avoided to prevent chemical reactions and deterioration. And its chemical structure is also active, and triethyl groups are in contact with strong oxidizing agents and reducing agents or react unexpectedly, so they should also be kept away from such substances when transporting.
Second words storage conditions. It needs to be placed in a cool, dry and well-ventilated place. Because the temperature is too high, or accelerate its chemical reaction rate, causing adverse changes such as decomposition and polymerization. Humid environment may cause hydrolysis, or adverse reactions with water vapor, so humidity control is necessary. At the same time, it may have a certain volatility, good ventilation can prevent gas accumulation and reduce safety risks.
Re-examine packaging requirements. Packaging must be tight and sealed. Commonly used glass bottles, plastic bottles, etc. are filled, and the bottles must be intact to prevent leakage. Key information such as name, nature, and hazard should be clearly marked on the outside of the package for identification and handling. During transportation, suitable containers and protective materials should be used to absorb shock, prevent collision, and ensure complete packaging.
Safety protection should not be ignored. Those who operate this substance should prepare suitable protective equipment, such as gloves, goggles, protective clothing, etc. Because it may be irritating to the skin, eyes, and respiratory tract, if you come into contact accidentally, you should take corresponding first aid measures immediately, such as rinsing with water, seeking medical attention, etc.
Storage 1% 2C2% 2C5-triethyl-3-carboxylbenzene, must follow the chemical substance storage and transportation specifications, know its characteristics in detail, and do a good job of protection and management to ensure safety and avoid accidents.