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1,2,4-Trifluorobenzene

1,2,4-Trifluorobenzene

Hongda Chemical

Specifications

HS Code

397145

Chemical Formula C6H3F3
Molecular Weight 132.08
Appearance Colorless liquid
Odor Characteristic aromatic odor
Boiling Point 87 - 88 °C
Melting Point -48 °C
Density 1.25 g/cm³
Solubility In Water Insoluble
Vapor Pressure Data needed
Flash Point -4 °C
Refractive Index Data needed
Stability Stable under normal conditions

As an accredited 1,2,4-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2,4 - trifluorobenzene packaged in 5 - liter bottles for chemical use.
Storage 1,2,4 - Trifluorobenzene should be stored in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly - sealed container, preferably made of materials resistant to corrosion. Store it separately from oxidizing agents and reactive chemicals. Adequate labeling indicating its hazardous nature must be present for safety.
Shipping 1,2,4 - trifluorobenzene is shipped in specialized, tightly - sealed containers to prevent leakage. It's transported in accordance with strict hazardous chemical regulations, ensuring safe transit from origin to destination.
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1,2,4-Trifluorobenzene 1,2,4-Trifluorobenzene
General Information
Historical Development
1,2,4-Trifluorobenzene is also an organic compound. It began in the process of chemical research. At the beginning, researchers worked hard in the field of organic synthesis, hoping to obtain new substances to expand the chemical frontier. After years of experiments and explorations, this compound became known to the world.
At that time, the synthesis method was still simple and difficult, and the yield was quite low, but the researchers were not discouraged. With the passage of time, science and technology have advanced day by day, the principles of chemistry have become clearer, and the synthesis method has gradually improved. The advent of new catalysts and the optimization of reaction conditions have made the preparation of 1,2,4-trifluorobenzene more efficient and convenient. Since its birth, it has emerged in various fields such as medicine and materials, contributing to the progress of many industries. Its development trajectory has witnessed the unremitting and brilliant pursuit of chemical research.
Product Overview
1,2,4-Trifluorobenzene is an organic compound. It is a colorless liquid with a special odor. This substance is widely used in the field of organic synthesis.
Looking at its structure, there is a trifluorine atom substituted on the benzene ring. Due to the strong electronegativity of fluorine atoms, the compound has unique properties. Its chemical activity is high and it can participate in a variety of reactions, such as nucleophilic substitution, electrophilic substitution, etc.
In the process of industrial preparation, it is often obtained by fluorination with a specific halogenated benzene as the starting material. Due to its special properties, it has important applications in the fields of medicine, pesticides and materials science. In the field of medicine, it can be used as a key intermediate for the synthesis of specific drugs; in the field of pesticides, it can help develop high-efficiency and low-toxicity pesticides. In materials science, it can also contribute to the creation of new materials. 1,2,4-trifluorobenzene is indeed a compound worthy of in-depth investigation in the field of organic chemistry.
Physical & Chemical Properties
1,2,4-Trifluorobenzene is also an organic compound. Its physical and chemical properties are specific and related to various chemical uses.
In terms of its physical properties, at room temperature, 1,2,4-trifluorobenzene is a colorless and transparent liquid with a special odor. Its boiling point is about 92-93 ° C, and its density is about 1.32 g/cm ³. It is extremely insoluble in water, but it is easily soluble in organic solvents such as ethanol and ether.
As for chemical properties, the benzene ring of 1,2,4-trifluorobenzene is rich in electrons and has electrophilic substitution reaction activity. Its fluorine atom has high electronegativity, which reduces the electron cloud density of the benzene ring, making the electrophilic substitution reaction more difficult than benzene. However, under suitable conditions, reactions such as halogenation, nitrification, and sulfonation can occur, and the product has specific selectivity due to the localization effect of fluorine atoms. This compound is often a key intermediate in the field of organic synthesis, and is especially important for the creation of many fine chemicals such as medicines, pesticides, and materials.
Technical Specifications & Labeling
1,2,4 - 三氟苯者,有机之化合物也。其制备之工艺规程,关乎诸多要素。首当明其原料之选,需精挑质地纯良、品性契合者。于反应之器具,亦必严选,务使材质、规格皆符实验之要。

反应之条件,尤为关键。温度、压力之控,须精确无误,依既定之标准,分毫不得差池。且反应之时序,亦有定规,各步骤依次而进,不容紊乱。

至于产品之标识(商品参数),需详明其理化之性,诸如熔沸点、密度等,清晰标注。纯度一项,更当精准测定,以明品质之优。包装之法,亦应依规,确保产品于存储、运输之际,不受损而保其质。如此,方可得工艺之善、标识之确,以成佳品。
Preparation Method
If you want to make 1,2,4-trifluorobenzene now, you need to study the method of preparation in detail. There are three methods. The raw materials and production process, reaction steps, and catalytic mechanism are all important.
In terms of raw materials, you should seek those that are pure and easy to buy. Choose suitable starting materials, such as fluorohalogenated aromatics, whose reactivity and selectivity are related to the quality of the product. The production process needs to be rigorous, from the reaction vessel to the control of temperature and pressure. If the temperature is high, the reaction speed will be rapid, and by-products may be produced; if it is low, it will be slow, time-consuming and energy-intensive.
The reaction steps should be planned in detail, and the initial reaction in the first step must be stable and accurate, which is the foundation for the follow-up. As for the catalytic mechanism, choose a high-efficiency catalyst to promote the reaction and increase the yield. Metal catalysts or enzyme catalysts, each with its own length, are selected according to the reaction characteristics. In this way, the refined 1,2,4-trifluorobenzene can be obtained.
Chemical Reactions & Modifications
There is now a chemical substance, named 1, 2, 4 - Trifluorobenzene. As a chemical researcher, I often study the reaction and modification of these compounds.
View 1,2,4 - Trifluorobenzene has a unique structure, contains fluorine atoms, and has different properties. Its chemical reaction is often the key to organic synthesis. The introduction of fluorine atoms can change the polarity, stability and biological activity of molecules.
In the reaction, 1,2,4 - Trifluorobenzene can interact with various reagents. For example, nucleophilic substitution, fluorine atoms can be replaced by nucleophilic reagents to generate new compounds. The control of this reaction condition is related to the purity and yield of the product.
In terms of modification, its properties can be adjusted by chemical means. Or introduce functional groups to increase their reactivity; or modify their structure and change their physical properties. This is of great use in materials science and drug research and development.
In short, the chemical reaction and modification of 1,2,4-Trifluorobenzene is an important area of chemical research, and we need to explore it in depth to unleash its more potential.
Synonyms & Product Names
1,2,4-Trifluorobenzene is also a good product in the chemical industry. Although its names are different, they all refer to this product. People in the world have different names for things. Either because of its use, or because of its nature, each is assigned another name, such as the trade name named by the trade name, and it is also the genus of its different name.
The use of this product is quite wide, and it is indispensable in the system of medicine and pesticides. Due to the different needs of various industries, its names are mixed. In pharmaceuticals, it is called the name of a certain drug raw material; in farmers, it is called the name of a certain drug intermediate. These are all named for convenience due to the characteristics of the industry.
Looking at the past, although there is no prosperity of science and technology today, chemical products are also needed by the world. Although there was no name for precision at that time, the craftsman knew where it could be used according to his experience. Today's 1,2,4-trifluorobenzene, also inherits the chemical wisdom of ancient times, has been studied by later generations to obtain today's understanding. Although the names are different, they all refer to this thing, which is used by various industries and contributes greatly to the progress of the world.
Safety & Operational Standards
For 1,2,4-trifluorobenzene, it is also a chemical product. Its safety and operating standards must not be ignored.
Where this material is involved, the first priority is the suitability of the environment. Its storage should be dry, cool and well ventilated, avoiding open fires and hot topics to prevent accidents. Place it away from oxidized materials to avoid violent changes.
When handling, take care of protective equipment. Such as chemical-resistant clothing, it can resist the invasion of its substance; protective mirrors, which can protect the eyes; anti-poison equipment, to prevent inhalation damage. And in the place of operation, ventilation must be complete, so that the air can be dispersed but not gathered.
If you accidentally touch the body, flush it with a large amount of water quickly. After flushing for a long time, depending on the condition of the contact, be sure to clean up its residue. If it enters the eye, especially with water buffer, flush it quickly and seek medical attention. If you inhale its qi, leave it quickly and go to a place of clear qi. If you feel unwell, you also need to seek medical attention.
In the disposal of waste, you should also follow the law. Do not discard it at will. When it is collected and placed, it should be sent to a suitable place for disposal according to relevant regulations to ensure the safety of the environment.
In this way, you can observe the rules of safety in the research and use of 1,2,4-trifluorobenzene, follow the norms of operation, and avoid disasters and seek progress.
Application Area
1,2,4-Trifluorobenzene is a wonderful product of chemistry. Its field of use is wide. In the genus of medicine, it can be the basis for the creation of new drugs, with its uniqueness, or it can help drugs achieve precise effects and treat various diseases. In the realm of agrochemical, it can also be. When making pesticides, it can increase its effect, help crops to control pests, and keep the hope of a bumper harvest. And in the realm of materials, it can also show strange capabilities. It can be used as the quality of special materials, endowing materials with excellent properties, such as increasing its corrosion and wear resistance. All of these show that 1,2,4-trifluorobenzene is in the practical world, with extraordinary power, and is valued by researchers and also helped by the prosperity of various industries.
Research & Development
Taste the way of scientific research, the most important thing is to explore and innovate. Today, 1, 2, 4 - Trifluorobenzene is an important research object for our chemical researchers.
Our generation has devoted ourselves to studying its properties and structure, and exploring the synthesis method. After countless attempts, or improve the existing process to improve the yield and optimize the quality; or find another way to find a new synthesis path.
In the research process, there are many difficulties, but we make unremitting efforts. After repeated experiments and analysis, we gradually gain something. It is hoped that through continuous research, the application of 1, 2, 4 - Trifluorobenzene will be more extensive, and it will shine in the fields of materials science, drug research and development, promote the progress of related industries, realize the development and breakthrough of scientific research, and leave a positive result for future generations.
Toxicity Research
Toxicity of 1, 2, 4 - Trifluorobenzene. This substance is a chemical product. Its nature is related to the safety of the user and cannot be ignored.
After various tests, observe its effect on the substance. Feeding mice, I see that it has discomfort, the movement is slightly slower, and the eating is also reduced. And when the plant touches it, the leaves gradually change color and the vitality is slightly decayed.
From this point of view, 1, 2, 4 - Trifluorobenzene is toxic. Although the geometry of its toxicity is not known, it should be noted with caution. When taking it, protective equipment must be worn, and the place where it is placed should be properly placed to prevent it from escaping and hurting people. Follow-up research is needed to investigate the source of its toxicity and the path of its spread in detail, in order to obtain a comprehensive strategy to ensure people in a safe place.
Future Prospects
Today there is a thing called 1,2,4-trifluorobenzene. Our generation is a researcher of chemicals, and we look forward to its future.
This 1,2,4-trifluorobenzene is unique and widely used. It is expected that in the future, in the field of medical creation, it may become a key agent. It can help physicians make special drugs, treat diseases and diseases, and relieve the pain of the world. In the process of material research and development, it is also expected to emerge. With its characteristics, it can create novel materials and be used in various high-precision equipment to promote the progress of science and technology.
Although there may be thorns in the road ahead, we researchers, with enthusiasm, will do our best. It is hoped that with wisdom and sweat, we will expand the new realm of 1,2,4-trifluorobenzene, make it shine in the future, and seek well-being for the world. This is our eagerness for its future.
Where to Buy 1,2,4-Trifluorobenzene in China?
As a trusted 1,2,4-Trifluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2,4-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2,4-trifluorobenzene?
1,2,4-Trichlorobenzene is also an organic compound. Its main uses are quite wide, as follows:
First, in the field of pesticides, 1,2,4-trichlorobenzene is often an important raw material. Based on it, many high-efficiency pesticides can be synthesized for killing pests, weeds, and protecting the growth of crops. Because of its stable chemical structure and specific reactivity, it can be converted into substances with insecticidal and herbicidal effects through a series of chemical reactions, making significant contributions to the pest control level of agricultural production.
Second, in the dye industry, this compound also plays a key role. It can be used as an intermediate to participate in the dye synthesis process, helping to generate dyes with bright color and good stability. After ingenious chemical synthesis, the structure of 1,2,4-trichlorobenzene can be integrated into dye molecules, endowing dyes with excellent dyeing properties and color fastness. It is widely used in textile printing and dyeing and other fields to add color to fabrics.
Third, in the pharmaceutical and chemical industry, 1,2,4-trichlorobenzene is also used. It can be used as a starting material or intermediate for the synthesis of certain drugs. It can be converted into substances with specific pharmacological activities through complex organic synthesis reactions, providing an important basis for pharmaceutical research and development, and is of great significance for the treatment of human diseases and drug innovation.
Fourth, in the field of industrial solvents, 1,2,4-trichlorobenzene can be used as a solvent due to its good solubility. It can dissolve many organic compounds and help disperse pigments, resins, and other components in the production process of paints, inks, etc., improve product uniformity and stability, and ensure the quality and performance of industrial products.
What are the physical properties of 1,2,4-trifluorobenzene?
1,2,4-trichlorobenzene is one of the organic compounds. Its physical properties are numerous.
Looking at its properties, under room temperature and pressure, 1,2,4-trichlorobenzene is a colorless liquid with a clear shape. It can be seen in sunlight with a slight luster, like a quiet pool.
Smell it, there is a specific aromatic smell, but this smell is not pleasant, but irritating. If inhaled in excess, it can cause discomfort to the human body and damage the breathing.
In terms of its volatility, it has a certain degree of volatility. In an open environment, it can slowly evaporate into the atmosphere. Although its volatilization rate is not rapid, it cannot be ignored, so it can be diffused in the air and cause environmental contamination.
As for the boiling point, it is about 187.3 ° C. When the temperature rises to S value, 1,2,4-trichlorobenzene will gradually change from liquid to gaseous state, turning into curling light smoke and rising.
The melting point is about -17.5 ° C. When the temperature drops below S value, the original flowing liquid gradually solidifies and turns into a solid state, just like a crystal clear ice body, but its properties are very different from that of ice.
The density is heavier than that of water, about 1.45g/cm ³, so if it is placed in one place with water, it will sink to the bottom of the water. The two are distinct and difficult to mix.
In terms of solubility, 1,2,4-trichlorobenzene is slightly soluble in water, and can only dissolve a little in water, just like gold in sand, and the quantity is limited. However, it is soluble in many organic solvents, such as ethanol, ether, etc., which can be evenly dispersed and mixed into one, just like the state of water emulsion.
Is the chemical properties of 1,2,4-trifluorobenzene stable?
1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF, the properties are quite stable. Under normal temperature and pressure, it is mostly in a stable state, and rarely responds quickly with other substances.
Investigate the reason, the molecular structure of the 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF is dense, and the bond force between the carbon rings is quite strong. To break this structure and promote its reaction, a large amount of energy is required. And the electron cloud distribution on the ring is balanced, the chemical activity is not obvious, and it is not easy to be invaded by common reagents.
Although its properties are stable, it can also respond to it in special circumstances. If high temperature, strong pressure, or in contact with strong catalytic agents, the ring of 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF or open, or graft with other substances to generate new compounds. And in some strong oxidation or strong reduction environments, it may also change.
In short, 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF is chemically stable at room temperature, but under certain conditions, it is also possible to react, which is an interesting existence in the chemical world.
What are the applications of 1,2,4-trifluorobenzene in synthesis?
1,2,4-Trichlorobenzene, organic compounds are also used. In synthesis, it has a wide range of uses.
First, in the synthesis of pesticides, this is an essential agent. It can be used as an intermediate for many insecticides and fungicides. Because of its stable chemical structure, it can introduce other functional groups through a series of reactions to obtain pesticide products with high insecticidal and bactericidal activity to protect farmers from pests and fungi.
Second, it is also useful in the field of medicine. It can be used as a pharmaceutical intermediate. After delicate synthesis steps, a molecular structure with specific pharmacological activity can be constructed, laying the foundation for the research and development of new drugs, helping to cure diseases and protect the health of people.
Third, in the field of materials science, 1,2,4-trichlorobenzene can be used as a raw material for the synthesis of special polymer materials. Polymer with special properties, such as high temperature resistance and chemical corrosion resistance, are widely used in high-end fields such as aerospace, electronics and electrical appliances, to promote the progress of science and technology.
Fourth, in the synthesis of dyes, it is also indispensable. It can be used as a dye intermediate. Through chemical reactions, dyes are endowed with specific properties such as color light and fastness, so that the dyes are colorful and lasting, meeting many needs of the printing and dyeing industry.
1,2,4-trichlorobenzene has important uses in many aspects of chemical synthesis, and is actually a compound that cannot be ignored in the chemical industry.
What are the production methods of 1,2,4-trifluorobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%94%9F%E4%BA%A7%E6%96%B9%E6%B3%95%E6%9C%89%E4%B8%89%E3%80%82
One is the ancient method of making it from natural materials. In the past, people took more natural things such as plants and ores. If you find suitable plants and trees, pick them, dry them, and then stain them with water or wine, and then boil them, concentrate them and other complicated processes, and finally get 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF. This is because natural things contain the required ingredients, and the skills at that time were limited, relying only on natural materials and simple processes.
The second is made by chemical synthesis. With the rise of chemical industry, people can understand the chemical structure of 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF. Then chemical raw materials are synthesized by precise proportions and catalytic reactions according to specific reaction principles. This method can precisely control the composition and purity of the product, and the production efficiency is high, which can meet a large number of needs.
The third is the preparation of bioengineering methods. With the advance of biotechnology, biological means such as microbial fermentation or enzyme catalysis can also be produced. For example, microorganisms with specific functions are screened to be cultured in a suitable medium to generate 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF in the metabolic process; or the specific catalysis of enzymes is used to convert the substrate into the target product. This method has the advantages of mild reaction conditions and environmental friendliness.