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1,2,4-Trifluoro-5-Nitrobenzene

1,2,4-Trifluoro-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

294943

Chemical Formula C6H2F3NO2
Molecular Weight 181.08
Appearance Colorless to light yellow liquid or solid
Melting Point 28 - 30 °C
Boiling Point 193 - 194 °C
Density 1.559 g/cm³
Flash Point 80.5 °C
Solubility In Water Insoluble
Vapor Pressure Low
Odor Pungent

As an accredited 1,2,4-Trifluoro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 1,2,4 - trifluoro - 5 - nitrobenzene packaged in a sealed, corrosion - resistant bottle.
Storage 1,2,4 - Trifluoro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage. Since it is a hazardous chemical, ensure storage is in accordance with local safety regulations, away from incompatible substances.
Shipping 1,2,4 - Trifluoro - 5 - nitrobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported under regulated conditions, adhering to safety protocols for handling hazardous chemicals to prevent spills and ensure safe transit.
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1,2,4-Trifluoro-5-Nitrobenzene 1,2,4-Trifluoro-5-Nitrobenzene
General Information
Historical Development
1,2,4-Trifluoro-5-nitrobenzene is also an organic compound. At the beginning, chemists studied the physical properties and explored the preparation method. At the beginning, the preparation was difficult and the yield was quite low. However, scholars made unremitting efforts to study and improve.
After years, the technology has gradually matured. In the past, it was subject to conditions, the raw materials were rare and the reactions were complicated. After new techniques emerged, the raw materials were easy to make and the process was simplified. This compound has gradually shown its ability in the fields of medicine and materials, adding wings to scientific research and industry. Looking at its development, from the initial ignorance, it has been widely used today, just like a long river rushing forward, and it has become an indispensable existence in the field of chemistry. It is expected to show greater capabilities in the future.
Product Overview
The description of 1,2,4-trifluoro-5-nitrobenzene
There is a substance named 1,2,4-trifluoro-5-nitrobenzene. It is an organic compound with unique chemical properties. Looking at its structure, fluorine atoms and nitro groups are cleverly arranged on the benzene ring. Fluorine atoms have strong electronegativity, giving this substance a special electronic effect; nitro groups also have strong electron absorption, and the two work together to cause the compound to have different reactivity from normal substances.
The preparation process often involves fine organic synthesis. Or from benzene derivatives, through a series of reactions such as halogenation and nitrification, it can be carefully regulated. It has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to participate in the synthesis of many drugs and pesticides. Due to its unique structure, it can introduce specific functional groups, laying the foundation for the creation of new active compounds.
Although it is an important chemical material, it should be handled with caution. It has certain toxicity and danger. When operating, strictly follow the procedures and take good protection to prevent harm to people and the environment.
Physical & Chemical Properties
1,2,4-Trifluoro-5-nitrobenzene is also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its physical properties, it may appear in a specific state at room temperature, or have a specific color and taste. Melting point and boiling point are also characterizations of its characteristics, which are related to the transition temperature of its phase state.
Discussing chemical properties, because of its fluorine, nitro and other functional groups, it has unique reactivity. Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring and is prone to nucleophilic substitution reactions. The introduction of fluorine atoms changes the electron cloud distribution of the molecule and affects its reaction selectivity. And because of its structural characteristics, it has specific application value in the field of organic synthesis under different reaction conditions or exhibits different chemical behaviors, and can be an important raw material for the synthesis of compounds with special structures.
Technical Specifications & Labeling
"On the technical specifications and labeling (product parameters) of 1,2,4-trifluoro-5-nitrobenzene"
There are 1,2,4-trifluoro-5-nitrobenzene now, and the technical specifications are related to the preparation method. It needs to be made according to the precise ratio, with suitable raw materials, under suitable temperature and pressure, and through exquisite processes. During this period, the heat and duration need to be strictly controlled, and the difference is slightest, or the quality is different.
As for the label, when the product parameters are stated. Such as purity geometry, impurity geometry, this is the key identification of quality. And its physical properties, such as color, odor, melting point, etc., also need to be detailed. In this way, it is possible to make the person used clear at a glance, and to make the best use of it in various industries without making mistakes.
Preparation Method
The method of making 1,2,4-trifluoro-5-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often fluorinated and nitro-containing compounds, such as specific aromatic hydrocarbon halides. First take aromatic hydrocarbon halides, add fluorine sources, such as potassium fluoride, in a suitable solvent, and help them with a phase transfer catalyst to heat up the reaction. This is the fluorination step to obtain fluorine-containing intermediates.
Then, the intermediate and nitrifying reagents, such as mixed acids (nitric acid and sulfuric acid), react at controlled temperature to achieve the purpose of nitrification. During the reaction, pay attention to the temperature and the ratio of reagents to prevent side reactions.
In the catalytic mechanism, the phase transfer catalyst facilitates the transfer of ions in the two phases to promote the reaction. In the production process, raw material pretreatment, reaction condition control, and product separation are all heavy. After multi-step fine operation, high-purity 1,2,4-trifluoro-5-nitrobenzene can be obtained to meet the needs of chemical and other fields.
Chemical Reactions & Modifications
There is a chemical substance today, named 1,2,4-trifluoro-5-nitrobenzene. As a chemical researcher, I often study the chemical reaction and modification of this substance.
The way of its reaction depends on many factors. Temperature, pressure, and the genus of the catalyst can all be controlled. At a specific temperature and catalyst, it can react with a certain reagent to produce new compounds. However, this reaction may be insufficient, the rate is not ideal, and the purity of the product can also be improved.
As for modification, it is hoped to increase its stability, activity, etc. After various attempts, specific groups can be introduced, or their properties can be changed. However, the road to modification is not smooth, and difficulties are often encountered. It is necessary to repeatedly test and ponder in order to find the best way to obtain products with better performance, which can be used in a wider range of fields such as chemical industry.
Synonyms & Product Names
For 1,2,4-trifluoro-5-nitrobenzene, a chemical substance is also used. Its synonymous name and the name of the commodity are also exquisite. Ancient scholars sought to match the names of various chemical substances.
Today, 1,2,4-trifluoro-5-nitrobenzene, or another name, is due to chemical naming rules and habits. The name of the commodity ordered by the merchant may be for easy identification and memory, or according to its characteristics and uses.
Its synonymous name may be derived from its chemical structure characteristics, or inherit the naming tradition of its predecessors. The name of the commodity is related to the promotion of the market. Although the names are different, they actually refer to the same thing. When studying, scholars must scrutinize their synonymous names and commodity names in order to obtain their true meaning, clarify their nature and use, and use them for all kinds of chemical inquiry without confusion.
Safety & Operational Standards
In the case of 1,2,4-trifluoro-5-nitrobenzene, chemical substances are also used. In the course of research, it is safe to endanger the operation.
This substance is dangerous to a certain extent, and it is sexually active. Its smell is pungent and corrosive. If you accidentally touch the skin, wash it with a lot of water immediately, and wash it with soap. If it enters the eyes, wash it with water as soon as possible, and treat it urgently.
The operation of the product must be carried out in good condition, so that the poison and the substance can be dispersed quickly. The operator should use protective clothing, wear protective gloves, eye masks and gas masks, and have comprehensive protection before operating.
When stored, it should be placed in a place that is dry, dry and well-connected, and a source of ignition and heat. Do not mix with oxidizing or raw materials, etc., to prevent chemical reactions from causing danger.
On the way, also follow the instructions, and keep it in a container to keep it sealed and prevent leakage. The tools are clear and dangerous, and the company and the relevant personnel are aware of the danger of this material and the emergency treatment method.
Therefore, the safe operation of 1,2,4-trifluoro-5-nitrobenzene is the most important of research and development, etc. It should not be slack a little, and everyone must abide by it to ensure safety.
Application Area
1,2,4-Trifluoro-5-nitrobenzene is also a genus of chemical materials. It is widely used in the field of pharmaceutical research and development, and can be used as a key intermediate to help create special new drugs to relieve diseases. In the process of pesticide research and development, it can also be an active ingredient to obtain a good medicine for eliminating damage and protecting seedlings, and to ensure the abundance of crops. And in the context of material science, it can participate in the synthesis of new materials with specific properties, such as materials with excellent insulation or high heat resistance, which are suitable for many industries such as electronics. Looking at this compound, it has many uses and can be used in various fields to develop its capabilities, promote the progress of science and technology, and benefit the prosperity of people's lives.
Research & Development
In modern times, chemistry has flourished, and all kinds of substances are the object of research. Today there is 1, 2, 4 - Trifluoro - 5 - Nitrobenzene, and we are dedicated to studying it, hoping to make some progress.
The properties of this substance are studied in detail, and its shape, odor, and degree of melting are all examined. Knowing its solubility in different solvents, as well as its reaction to other substances, has been determined.
As for the method of its preparation, it has also been explored many times. Either improve the old technique, or create a new way, and strive for high efficiency and purity.
Looking forward to its development, it is expected to shine in the fields of medicine and materials. It can make special drugs to treat diseases; or it can be the foundation of new materials to increase the ability of equipment. We should persevere and conduct in-depth research, hoping to contribute to its development and benefit the world.
Toxicity Research
Yu Taste is dedicated to the study of poisons, and recently focused on 1,2,4-trifluoro-5-nitrobenzene. The study of its toxicity is of great importance to people's livelihood and the environment.
View 1,2,4-trifluoro-5-nitrobenzene, which has a special chemical structure. This structure may make it uniquely toxic. After various experiments, observe its impact on organisms. In microhabitats, if this substance is applied a little, it can be seen that the reproduction of microorganisms is hindered, and its metabolic path is also disturbed.
Furthermore, in animal tests, although it is a small amount, it also causes discomfort to the body. Or cause damage to organs, especially liver and kidney. It shows that its toxicity is not light. And this substance is difficult to degrade in the environment, and it may accumulate for a long time or become a serious problem.
Therefore, the study of toxicity cannot be slowed down. When the mechanism is studied, the countermeasures are found to protect all living things and maintain the peace of the environment.
Future Prospects
Today there is a substance named 1,2,4-trifluoro-5-nitrobenzene. In the eyes of our chemical researchers, this is a substance with great potential. Although it is now or only one of the microparticles in the laboratory, its future development is really promising.
Looking at the structure of this compound, it is unique and delicate, as if it contains endless possibilities. We speculate that in the field of materials science, it may be able to be turned into the cornerstone of new materials, enabling materials to have unprecedented characteristics, such as excellent electrical conductivity and extraordinary stability.
In the field of pharmaceutical research and development, it is also expected to emerge. It may become a sharp blade to overcome difficult diseases and bring good news to thousands of patients. Although the road ahead is long, we are committed to the heart of research, uphold the ambition of exploration, and firmly believe that its future will shine brightly, marking a bright trajectory in the sky of science.
Where to Buy 1,2,4-Trifluoro-5-Nitrobenzene in China?
As a trusted 1,2,4-Trifluoro-5-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2,4-Trifluoro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2,4-trifluoro-5-nitrobenzene?
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One, in the field of medicine, this compound is quite useful. It can be used as a key intermediate in drug synthesis, helping to create a variety of special agents. Because of its special chemical structure, it can accurately participate in many complex chemical reactions, just like a delicate tool in the hands of craftsmen, helping to build the complex structure of drug molecules. After scientific research, the drugs synthesized by it have significant therapeutic effects on specific diseases, or can regulate human physiology, or can fight pathogenic microorganisms, bringing good news to the health of patients.
Both, in the field of materials science, also have extraordinary performance. It can contribute to the development of new materials and improve the specific properties of materials. For example, the introduction of this substance in the synthesis of some polymer materials can improve the stability, flexibility or conductivity of materials. It is like endowing materials with unique endowments that make them stand out in different application scenarios. Whether it is high-end materials used in aerospace or plastic products for daily civilian use, they all show new faces and expand the boundaries of material applications.
The three are important research objects in the journey of scientific research and exploration. Scientists deepen their understanding of the field of organic chemistry by delving into their properties and reaction mechanisms. Its unique chemical behavior and reaction path are like doors to the palace of new knowledge, leading researchers to explore the mysteries of the chemical world, enrich the theoretical system of organic chemistry, pave a solid path for subsequent scientific research and innovation, and make chemical research move towards a deeper realm.
What are the physical properties of 1,2,4-trifluoro-5-nitrobenzene?
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This compound has special physical properties. Its properties are either solid or liquid, depending on the ambient temperature, pressure and other conditions. Under normal temperature and pressure, it mostly exists in a stable state.
On its melting point, due to the unique molecular structure, it has a specific value. The strength of the intermolecular force has a great influence on the melting point. The intermolecular force of the compound is moderate, so that its melting point is within a certain range, but the exact value needs to be determined by fine experiments.
The boiling point is also one of its important physical properties. The boiling point of a compound is related to the difficulty of its gasification. When the external pressure reaches a certain value, the compound is heated to the boiling point, that is, it changes from liquid to gaseous state. The boiling point of this compound reflects the amount of energy required for its molecules to break free from each other.
In terms of solubility, it varies in different solvents. In polar solvents, due to the polarity of the compound part of the structure, it may have a certain solubility. In non-polar solvents, its solubility may be very small. This property depends on the degree of matching between the polarity of the compound molecule and the polarity of the solvent.
Density is also a parameter characterizing its physical properties. Its density is related to the molecular weight and the degree of molecular packing. If the molecular mass is larger and the packing is relatively tight, the density may be higher; otherwise, it is lower. The density value of the compound can be accurately known through experimental measurement.
In addition, the refractive index of the compound cannot be ignored. The refractive index reflects the change of the propagation speed of light in it and is closely related to the molecular structure and electron cloud distribution of the compound. Accurate determination of refractive index is helpful to identify the purity of the compound and determine its structural characteristics.
What are the chemical properties of 1,2,4-trifluoro-5-nitrobenzene?
1% 2C2% 2C4-tribromo-5-nitrobenzene is an organic compound with unique chemical properties and important uses in many fields.
In this compound, the presence of bromine atoms and nitro groups greatly affects its chemical properties. Bromine atoms have strong electronegativity, which can reduce the electron cloud density of the benzene ring, making the benzene ring more susceptible to electrophilic substitution reactions. The nitro group is also a strong electron-absorbing group, which further enhances this effect. In electrophilic substitution reactions, the reaction check point is selected due to the localization effect of bromine and nitro groups. Generally speaking, bromine is an ortho-and para-localization group, and nitro is an interlocalization group. The combination of the two causes the reaction to mainly occur at specific locations.
Its chemical activity is also reflected in its ability to participate in a variety of chemical reactions. For example, under suitable conditions, bromine atoms can be replaced by other groups, such as reacting with nucleophiles to form new organic compounds, which is an important means of building carbon-heteroatomic bonds in organic synthesis. Nitro groups can also undergo reduction reactions and be converted into other functional groups such as amino groups, thereby expanding the application range of compounds.
In addition, the physical properties of the compound, such as melting point and boiling point, are also closely related to the molecular structure. The bromine atoms and nitro groups in its structure increase the intermolecular force, so that its melting point and boiling point may be higher than that of benzene.
In terms of stability, this compound is relatively stable to a certain extent due to the conjugation system of the benzene ring and the electron-absorbing interaction between the bromine atom and the nitro group, but it still reacts under certain conditions, such as high temperature, strong acid-base or strong oxidizing agent. In summary, the chemical properties of 1% 2C2% 2C4-tribromo-5-nitrobenzene are rich, providing a broad space for organic chemistry research and related industrial applications.
What is the preparation method of 1,2,4-trifluoro-5-nitrobenzene?
1% 2C2% 2C4-tribromo-5-fluorobenzene, this is an important chemical agent, and its preparation method is quite exquisite.
To prepare this substance, the following steps are often followed: First, use suitable starting materials, mostly compounds containing benzene rings, and introduce bromine atoms and fluorine groups by chemical means. Or activate the benzene ring first to enhance its reactivity, and then carry out bromination operation. When brominating, liquid bromine can be selected, and iron or iron tribromide is used as a catalyst to make bromine atoms replace hydrogen atoms at specific positions on the benzene ring one by one.
After the bromine atom is successfully introduced, the fluorine group introduction process is carried out. This step may require the help of special fluorination reagents, and under specific reaction conditions, such as suitable temperature, pressure and solvent environment, the fluoryl group can precisely replace the atoms at the corresponding positions on the benzene ring, and finally obtain 1% 2C2% 2C4-tribromo-5-fluorobenzene.
During this period, each step of the reaction needs to be carefully controlled. Due to a slight deviation in the reaction conditions, the product may be impure or other by-products may be formed. Therefore, from the purity of the raw material to the precise regulation of the reaction equipment are the keys to the preparation of this compound. And after each step of the reaction is completed, many processes such as separation and purification are required to obtain high-purity 1% 2C2% 2C4-tribromo-5-fluorobenzene to meet the needs of different fields.
What should be paid attention to when storing and transporting 1,2,4-trifluoro-5-nitrobenzene?
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First, this material is sensitive and afraid of light and heat. When hiding, it is advisable to choose a cool and dark place to avoid the disturbance of yang inflammation and high temperature. If exposed to the hot sun or a warm place, it may cause its qualitative change and lose its original effect.
Second, it is vulnerable to moisture. Therefore, the storage must keep the environment dry and prevent moisture from invading. If placed in a damp place, the water vapor will gradually stain, and there will be a risk of mildew and rot, and it will not be usable.
When transporting, prevent it from being shaken. This material is brittle and cannot withstand bumps and impacts. If it vibrates too much during the journey, it may be broken and damaged, and it cannot be used. When transporting, handle it with care and caution.
Furthermore, it is necessary to store it in isolation. Do not store it in miscellaneous places with other things, especially with corrosive and reactive things. To prevent interaction, cause its deterioration and failure, and endanger safety.
All these are 1%2C2%2C4-%E4%B8%89%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E6%97%B6%E6%89%80%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B9%8B%E4%BA%8B for storage and transportation. According to this, it can be stored in good quality and in good condition for use.