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1,2,3-Trifluoro-5-(Trifluoromethyl)Benzene

1,2,3-Trifluoro-5-(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

897648

Chemical Formula C7H2F6
Molecular Weight 200.08
Appearance Colorless liquid
Boiling Point Around 110 - 112 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Depends on temperature, but relatively low for a liquid of this type
Packing & Storage
Packing 1,2,3 - trifluoro - 5 - (trifluoromethyl)benzene packaged in 5 - liter containers.
Storage 1,2,3 - trifluoro - 5 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Ensure the storage location has secondary containment to handle potential spills.
Shipping 1,2,3 - trifluoro - 5 - (trifluoromethyl)benzene is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. Shipment may involve temperature - controlled environments to ensure stability during transit.
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1,2,3-Trifluoro-5-(Trifluoromethyl)Benzene 1,2,3-Trifluoro-5-(Trifluoromethyl)Benzene
General Information
Historical Development
1,2,3-Trifluoro-5- (trifluoromethyl) benzene, the beginning of this product can be traced back to the study of the chemical sages in the past. At that time, Zhugong dedicated himself to expanding the territory of chemistry. At first, the understanding of it was still shallow, and it was only tested in the laboratory. After years of tempering, the experimental techniques have become more and more exquisite, and its physical and chemical properties have gradually become clear. Scholars continue to explore better preparation methods, and strive to improve the yield and purify the quality. From the initial difficult exploration to the follow-up process, every step has been soaked in the efforts of Zhugong. With the passage of time and the continuous improvement of technology, this compound has emerged in various fields such as chemical engineering and materials, and its application has become increasingly widespread. It has become a key point in the development of chemistry, witnessing the long road of chemical exploration.
Product Overview
1,2,3-Trifluoro-5- (trifluoromethyl) benzene, Product Overview
The 1,2,3-trifluoro-5- (trifluoromethyl) benzene studied today is a unique property among organic fluorides. Its properties are colorless and transparent liquids with a special odor, and it is widely used in many fields of chemical industry.
This product has excellent chemical stability due to the presence of fluorine atoms in the molecular structure. In the field of materials science, it is often used as a key raw material for high-performance materials. If a special coating is prepared, the corrosion resistance and wear resistance of the coating can be significantly enhanced, making the coated product durable in harsh environments.
In the field of medicinal chemistry, 1,2,3-trifluoro-5- (trifluoromethyl) benzene also plays an important role. Because it can change the physical and chemical properties of compounds, it helps to develop new special drugs and contributes to the cause of human health.
However, the development of this product also faces challenges. The synthesis process requires precise control of reaction conditions, which requires high technical requirements. However, we chemical researchers should make unremitting efforts to improve technology and make 1,2,3-trifluoro-5- (trifluoromethyl) benzene better serve the society.
Physical & Chemical Properties
1,2,3-Trifluoro-5- (trifluoromethyl) benzene is a unique chemical substance. Its physical and chemical properties are worth studying. Looking at its properties, it is a colorless and transparent liquid at room temperature, with a special odor. As far as its boiling point is concerned, it is in a specific temperature range, which is related to the strength of the intermolecular force. Its density is different from that of water, and its solubility shows a unique law in many solvents, or it is easily soluble in a certain type of organic solvent, but difficult to dissolve in water, which is determined by its molecular structure. Its chemical properties are also characteristic, and fluorine-containing groups give it high chemical stability. Under specific conditions, it can participate in chemical reactions and exhibit unique reactivity. Chemists explore this substance, hoping to gain insight into its characteristics, and find new opportunities for the development of chemical, materials and other fields.
Technical Specifications & Labeling
1,2,3-Trifluoro-5- (trifluoromethyl) benzene, the technical specifications and identification (product parameters) of this chemical are extremely critical. Its preparation requires a precise process, and the selection of raw materials must be pure and free of impurities. Depending on its properties, it may be a colorless and transparent liquid at room temperature, with a special odor and certain volatility.
In terms of technical specifications, the purity should reach a very high standard, and the impurity content must be strictly controlled. Physical parameters such as boiling point and melting point also have precise ranges to ensure stable product quality. On the label, in addition to clearly marking the chemical name, it is also necessary to indicate the hazardous characteristics, such as whether it is flammable, toxic, etc., so that users can handle it with caution. In this way, this chemical can be used safely and efficiently in various fields.
Preparation Method
The preparation of 1,2,3-trifluoro-5- (trifluoromethyl) benzene is related to the raw materials and production process, reaction steps and catalytic mechanism, which is the most important thing for our chemical researchers.
The selection of raw materials needs to be carefully selected. Based on specific halogenated aromatics and fluorine-containing reagents, the two are properly adapted to be the basis of the reaction. Halogenated aromatics need to have high purity, impurities do not disturb the reaction process; fluorine-containing reagents have moderate activity to promote a smooth reaction.
Production process, the first reaction conditions are controlled. Temperature should be precisely controlled. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow. Pressure is also the key, and the pressure can increase the chance of molecular collision and increase the reaction rate.
The reaction step starts with the fusion of halogenated aromatics and fluorine-containing reagents. With the help of the catalytic mechanism, fluorine atoms ingeniously replace halogen atoms. The catalytic mechanism is crucial, and the specific catalyst can reduce the activation energy of the reaction and make the reaction occur efficiently. This process requires fine monitoring to ensure that each step of the reaction is complete and the purity of the product is up to standard, so that high-quality 1,2,3-trifluoro-5- (trifluoromethyl) benzene can be obtained.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, the changes are endless, and the properties of substances can be changed by human labor. Today there is a thing called 1, 2, 3 - Trifluoro - 5 - (Trifluoromethyl) Benzene, and its chemical reaction and modification have a lot to study.
This compound has many fluorine atoms, and the characteristics of fluorine are active and highly electronegative, making the substance unique in its reactivity. Among many reactions, either electrophilic or nucleophilic, are changed by the presence of fluorine. The way to modify it is to optimize its performance, or increase its stability, or improve its solubility, or adjust its reaction selectivity.
If you want to do a good job, you must first study its rationality. Observe its structure, think about its electron cloud distribution, and explore the reaction mechanism in order to find a good solution for modification. After repeated experiments, adjusting conditions, and changing reagents, we hope to achieve an ideal environment, so that this compound can be used in materials, medicine, and other fields to develop its extraordinary capabilities, adding to the chemical industry and enhancing the charm and function of chemistry.
Synonyms & Product Names
1,2,3-Trifluoro-5- (trifluoromethyl) benzene, its trade name is the same, and it needs to be investigated in the research of chemical industry. The name of the chemical is the same, and it is often born due to the use, location, and research.
As far as 1,2,3-trifluoro-5- (trifluoromethyl) benzene is concerned, the name is based on the chemical industry and characteristics. This name is not limited to science, which is convenient for the exchange of research results. However, in business, it is for the convenience of publicity, the market, or there may be different trade names. This trade name, or one of its special properties, or with an eye to the target customer group, seeks to be exposed in the market.
Therefore, we, the researchers of transformation, face the difference in the name of such things, add discrimination, and explore their essence with the knowledge of science, so as to be able to conduct research on the road of transformation, without the complexity of the name.
Safety & Operational Standards
For 1,2,3-trifluoro-5- (trifluoromethyl) benzene, chemicals are also used. The safety and operation specifications of this object are of paramount importance and should not be ignored.
Where handling this object, the first priority is safety protection. The operator should wear special protective clothing, such as chemical-resistant protective clothing, which can prevent direct contact between the skin and the object and cause damage. Goggles must also be worn to protect the eyes to prevent this object from splashing into the eyes and damaging the eyesight. Protective gloves must be worn, and the material must be adapted to ensure effective protection.
In the place of operation, good ventilation must be required. This substance may be volatile. If the ventilation is not smooth, the gas will accumulate in the room, which is harmful to breathing, and the second may be at risk of ignition and explosion. Therefore, when setting up ventilation equipment, the indoor air will be always fresh and the airflow will be smooth.
When storing, there are also regulations. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Do not mix with oxidants, acids and other substances to prevent chemical reactions from occurring and causing danger. When the storage device is well sealed and clearly marked, indicate the name of the object, characteristics and hazards.
If you accidentally come into contact with this substance, you should deal with it quickly. If the skin touches it, rinse it with a lot of water immediately, and then seek medical treatment. If it enters the eye, rinse it with water as soon as possible. When rinsing, the eye must be turned so that it can be washed and then seek medical attention. If you inhale its gas, leave the scene quickly and go to a fresh air place. If you feel unwell, rush to medical attention.
In short, when handling 1,2,3-trifluoro-5- (trifluoromethyl) benzene, you must follow safety and operating standards, and be careful to be safe.
Application Area
1,2,3-Trifluoro-5- (trifluoromethyl) benzene, the application field of this chemical is of far-reaching significance. In the field of pharmaceutical research and development, it can lay the foundation for the creation of new specific drugs and help doctors overcome diseases. Due to the special properties of fluorine atoms, the activity and stability of compounds can be changed to achieve the purpose of precision treatment.
In the field of materials science, it can be used as a key raw material for the synthesis of special materials. With this material, materials with excellent properties can be prepared, such as high temperature resistance and corrosion resistance, which are widely used in cutting-edge fields such as aerospace and electronics.
Furthermore, it is also indispensable in the research and development of agricultural chemicals. It can be used to synthesize high-efficiency and low-toxicity pesticides, protect farmland crops from pests, maintain agricultural harvests, and benefit people's livelihood. All these show the importance of 1,2,3-trifluoro-5- (trifluoromethyl) benzene in various application fields.
Research & Development
Modern chemistry has been refined, and new things have emerged one after another. Today, there is 1, 2, 3 - Trifluoro - 5 - (Trifluoromethyl) Benzene, which has a specific nature and is the focus of research by scholars.
We have worked hard to explore the microstructure of its structure and study the wonder of its reaction. At first, we analyzed its molecular structure to understand the reason for its chemical properties. We also observed its changes under different conditions, or the rise and fall of temperature, or the addition and subtraction of agents, and recorded its changes in detail, hoping to gain something.
After months of research, it gradually became clear that it is on the way to synthesis, and can be used as a key agent to induce reactions to form new substances. And its stability is good, and it may be useful in various fields of materials. Over time, if we can make good use of it, we will be able to contribute to the development of chemistry, open up new frontiers, and make profound progress.
Toxicity Research
The toxicity of 1, 2, 3-trifluoro-5- (trifluoromethyl) benzene was studied. This substance has specific properties and is often used as a key raw material in various chemical reactions.
In the past, there were many studies on its chemical properties and preparation methods, but in the study of toxicity, there was still a lack of. We investigated its impact on organisms in detail to understand its potential harm.
Take several kinds of experimental organisms and put them into this substance to observe its physiological changes. Over time, the tested organisms showed abnormal behavior, or poor diet, or slow movement. Some biological organs showed signs of disease, especially liver and kidney.
From this perspective, 1,2,3-trifluoro-5- (trifluoromethyl) benzene is quite toxic. Subsequent to production and use, strict protective measures should be set up to prevent its harm and life, and ensure the tranquility of the environment.
Future Prospects
I look at the industry of chemistry today, 1, 2, 3 - Trifluoro - 5 - (Trifluoromethyl) Benzene, this compound has extraordinary prospects. It has potential and great uses in materials science, pharmaceutical research and development and other fields.
In the future, in materials science, it may be possible to assist in the research of new high-performance materials with its unique chemical properties, such as special coatings with super weather resistance and high stability, so that the utensils can last for a long time. In the field of medicine, it may be a key raw material for the creation of new drugs with special effects, overcoming difficult diseases and solving the suffering of patients.
Although the road to research and development may be difficult at present, everyone in scientific research has great ambitions and is determined to study. I firmly believe that in time, 1, 2, 3 - Trifluoro - 5 - (Trifluoromethyl) Benzene will shine brightly, painting a magnificent new chapter for human well-being and technological progress, and uncovering an endless future.
Frequently Asked Questions
What are the main uses of 1,2,3-trifluoro-5- (trifluoromethyl) benzene?
1,2,3-Tribromo-5- (tribromo-methyl) benzene is a highly toxic substance, and its main use involves many dangerous areas, which are rarely touched by ordinary people. In the past, or occasionally used in specific organic synthesis experiments, it is not suitable for ordinary use because of its strong toxicity and great harm.
This substance has strong chemical activity. In the past organic chemistry research process, some researchers may have used it as a raw material to participate in the construction of complex organic compounds. However, its toxicity is very serious. If it is not handled carelessly, it will endanger personal safety and cause serious pollution to the surrounding environment.
Due to its toxicity and potential environmental risks, strict regulations are now in place for its use, storage and disposal in many countries and regions. Even if it is required in specific scientific research scenarios, it must follow extremely high safety standards and procedures to ensure the safety of scientific researchers and the environment. In short, these highly toxic substances are not commonly used for the benefit of people's livelihood, but special chemicals that need to be treated with caution and strictly controlled.
What are the physical properties of 1,2,3-trifluoro-5- (trifluoromethyl) benzene?
1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene is an organic compound. Its physical properties are as follows:
Looking at its morphology, under normal conditions, the compound may be in a solid state. As for the color, it may be white to light yellow powder, or it may be crystalline, depending on its purity and preparation method.
When it comes to melting point, due to its specific molecular structure, it has a relatively fixed melting point value. However, the exact melting point needs to be determined according to experiments, and it is roughly within a certain temperature range. The establishment of this temperature range depends on many factors such as the strength of intermolecular forces and the regularity of structures.
In terms of boiling point, due to the intermolecular forces of the compound including van der Waals forces and possible hydrogen bonds, it wants to transform from liquid to gaseous state, and needs to absorb a certain amount of energy to overcome these forces. Therefore, the boiling point is also a specific value, which reflects the firmness of the intermolecular bonding.
In terms of solubility, in organic solvents, such as common benzene, toluene and other aromatic hydrocarbon solvents, because of their structure similarity, according to the principle of "similarity and miscibility", the compound may have good solubility; in polar solvents, such as water, because of its large polarity difference with water molecules, the interaction force is weak, so the solubility is poor, or slightly soluble or even insoluble.
density is also one of its important physical properties. Its density value depends on the mass of the molecule and the density of the molecule. When studying its behavior in mixing with other substances or in a specific environment, density is a key consideration.
What are the chemical properties of 1,2,3-trifluoro-5- (trifluoromethyl) benzene?
1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene is an organic compound with unique chemical properties, which is now known in ancient Chinese.
This compound contains many bromine atoms, and bromine is a halogen element, which is active. In chemical reactions, due to the presence of bromine atoms, 1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene often has a tendency to electrophilic substitution. Its benzene ring structure has a certain stability, but many bromine atoms are attached to it, which changes the density distribution of electron clouds in the benzene ring.
In the electrophilic substitution reaction, the electron-absorbing effect of bromine atoms causes the electron cloud density of the adjacent and para-site of the benzene ring to decrease relatively, and the electron cloud density of the meta-site is relatively high. Therefore, electrophilic reagents are more likely to attack the meta-site.
And because it contains tribromomethyl, this group also affects the overall properties of the compound. Tribromomethyl has a large steric resistance. In some reactions, it will prevent the reagent from approaching the benzene ring, affecting the reaction rate and selectivity.
In the redox reaction, the valence state of bromine in this compound is relatively stable and is not easy to be oxidized or reduced. However, under the action of specific strong oxidizing agents or reducing agents, the valence state of bromine atoms may be changed,
In addition, 1% 2C2% 2C3 -tribromo-5- (tribromo-methyl) benzene has a certain solubility in organic solvents due to molecular polarity and structure. Different organic solvents have different solubility, which is crucial in separation, purification and reaction medium selection.
What are the synthesis methods of 1,2,3-trifluoro-5- (trifluoromethyl) benzene?
1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzoic acid has many synthesis methods, and the main ones are selected here.
First, the bromination reaction can be carried out with bromine in the presence of a specific catalyst through benzoic acid as the starting material. When benzoic acid is co-placed in the reactor with bromine and suitable catalysts such as iron powder or iron tribromide, under suitable temperature and reaction conditions, bromine atoms gradually replace the hydrogen atoms on the benzene ring to form bromine-containing benzoic acid derivatives. However, this process requires precise control of the reaction temperature, bromine dosage and reaction time to prevent excessive bromination or insufficient reaction. After sufficient bromine atoms are introduced into the benzene ring, the methyl group is brominated. N-bromosuccinimide (NBS) and other brominating reagents can be selected. Under the action of initiators such as benzoyl peroxide, methyl groups can be brominated to obtain the target product 1% 2C2% 2C3-tribromo-5 - (tribromo-methyl) benzoic acid. This path step is relatively clear, but the control of the reaction conditions is strict.
Second, toluene can also be used as the starting material. First, toluene is brominated, and brominated on the benzene ring is catalyzed by bromine and toluene. Because methyl is an ortho-para-site group, bromine atoms are mainly substituted in ortho-sites and para-sites. Subsequent oxidation steps oxidize methyl to carboxyl groups. Commonly used oxidants such as potassium permanganate can achieve the transformation of methyl to carboxyl in a suitable reaction medium. At the same time, if the degree of bromination on the benzene ring does not meet the target requirements, bromine and catalyst can be further added for secondary bromination to achieve the structural requirements of 1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzoic acid. The starting material of this route, toluene, is relatively common and inexpensive, but involves an oxidation step. It is necessary to pay attention to the effect of reaction conditions on the purity and yield of the product.
Third, other compounds containing benzene rings with appropriate substituents can also be considered as starting materials. Through multi-step reactions, bromine atoms and carboxyl groups are gradually introduced, and their positions and numbers are adjusted to finally synthesize 1% 2C2% 2C3 -tribromo-5 - (tribromo methyl) benzoic acid. However, such methods are often cumbersome, and the reaction route needs to be carefully designed and the reaction conditions optimized at each step to improve the efficiency of the overall reaction and the purity of the product.
What are the precautions for using 1,2,3-trifluoro-5- (trifluoromethyl) benzene?
1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF, this is an organic compound. When using it, many matters need to be paid attention to.
First safety protection. This compound may be toxic and irritating. When operating, be sure to wear appropriate protective equipment, such as protective gloves, protective glasses, gas masks, etc., to prevent skin contact, inhalation or accidental ingestion, so as to avoid damage to the body.
Furthermore, pay attention to storage conditions. It should be stored in a cool, dry and well-ventilated place, away from fire sources, heat sources and oxidants. Because it may be flammable, improper storage is prone to fire and other hazards. At the same time, it should be sealed and stored to prevent it from evaporating or reacting with components in the air, affecting its quality and performance.
During use, strictly follow the operating procedures. Accurately control the dosage and do not increase or decrease it at will. According to specific experimental or production needs, use and operate with the help of suitable instruments and methods. If a chemical reaction is involved, it is necessary to fully understand its reaction characteristics and conditions, and strictly control the reaction temperature, time and other parameters to ensure the smooth progress of the reaction and avoid unexpected situations.
In addition, do a good job of waste disposal. After use, the remaining compounds and related waste must not be discarded at will. It is necessary to properly dispose of them in accordance with relevant regulations to prevent pollution to the environment.
1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF used, safety and regulations must be kept in mind and careful operation can ensure the safety of personnel and the smooth development of work.